141 results match your criteria Case reports in nephrology and dialysis[Journal]


Giant Brachial Aneurysm after Arteriovenous Fistula Ligation: A Review of the Different Surgical Approaches.

Case Rep Nephrol Dial 2020 May-Aug;10(2):57-64. Epub 2020 May 27.

Department of Vascular Surgery, San Salvatore Hospital, University of L'Aquila, L'Aquila, Italy.

The aim of this paper is to describe the case of a patient successfully treated for left brachial arterial aneurysm occurring 15 years after renal transplantation and consequent 8 years after arteriovenous fistula (AVF) ligation. We describe our experience and our surgical approach. A 45-year-old man presented to our attention for a large pulsatile formation on the volatile face of the left forearm, which he reported to have enlarged in the last year. Read More

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http://dx.doi.org/10.1159/000507427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315194PMC

Cat Rearing: A Potential Risk of Fulminant Sepsis Caused by in a Hemodialysis Patient.

Case Rep Nephrol Dial 2020 May-Aug;10(2):51-56. Epub 2020 May 13.

Department of Hematology, Jyoban Hospital of Tokiwa Foundation, Fukushima, Japan.

is a commensal organism colonized in oral flora of dogs and cats and causes severe sepsis through bite wound in immunocompromised patients. To date, hemodialysis has not been reported as a risk of infection. A 75-year-old woman with end-stage renal disease secondary to hypertension suddenly developed septic shock. Read More

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http://dx.doi.org/10.1159/000507425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265706PMC

Acute Kidney Injury Associated with Minimal Change Nephrotic Syndrome in an Elderly Patient Successfully Treated with both Fluid Management and Specific Therapy Based on Kidney Biopsy Findings.

Case Rep Nephrol Dial 2020 Jan-Apr;10(1):42-50. Epub 2020 Apr 22.

Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

Oliguric acute kidney injury (AKI) with minimal change nephrotic syndrome (MCNS) has long been recognized. Several mechanisms such as hypovolemia due to hypoalbuminemia and the nephrosarca hypothesis have been proposed. However, the precise mechanism by which MCNS causes AKI has not been fully elucidated. Read More

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http://dx.doi.org/10.1159/000507426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204776PMC

Catheter Access Management for Acute Peritoneal Dialysis.

Case Rep Nephrol Dial 2020 Jan-Apr;10(1):35-41. Epub 2020 Apr 14.

Pediatric Intensive Care Unit, Bachir Ben Nacer Hospital, Biskra, Algeria.

Insertion of a peritoneal dialysis (PD) catheter is frequently done by interventional nephrologists, but these procedures are typically only performed for adults. Almost all invasive procedures in children are performed by pediatric surgeons. If a pediatric surgeon is unavailable, the initiation of PD in acute situations may be delayed, thus increasing the risk of complications and chronic kidney disease. Read More

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http://dx.doi.org/10.1159/000506674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184793PMC

A Case of Acute Kidney Injury in a Patient with Renal Hypouricemia without Intense Exercise.

Case Rep Nephrol Dial 2020 Jan-Apr;10(1):26-34. Epub 2020 Mar 30.

Department of Nephrology, Shinshu University School of Medicine, Matsumoto, Japan.

Exercise-induced acute kidney injury (EIAKI) frequently develops in patients with renal hypouricemia (RHUC). However, several cases of RHUC with acute kidney injury (AKI) but without intense exercise have been reported. We encountered a 15-year-old male with RHUC who experienced AKI. Read More

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http://dx.doi.org/10.1159/000506673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154233PMC

Effective Management of Peritoneal Dialysis-Associated Hydrothorax in a Child: A Case Report.

Case Rep Nephrol Dial 2020 Jan-Apr;10(1):18-25. Epub 2020 Feb 12.

Department of Child Health, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta Pusat, Indonesia.

Peritoneal dialysis (PD) confers many advantages, including a better quality of life for children with end-stage renal disease; however, the procedure is associated with several complications, including pleuroperitoneal leaks. Here, we report an unusual case of hydrothorax caused by long-term PD in a child, which was further complicated by pneumonia. A 9-year-old boy who had received CAPD for 22 months presented with dyspnea, swelling, and increased body weight. Read More

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http://dx.doi.org/10.1159/000506119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098331PMC
February 2020

Long-Term Effects of High-Dose Tolvaptan for Autosomal Dominant Polycystic Kidney Disease Patients.

Case Rep Nephrol Dial 2020 Jan-Apr;10(1):9-17. Epub 2020 Feb 12.

Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.

Tolvaptan, a vasopressin V2 receptor antagonist, was initially approved in Japan for treatment of autosomal dominant polycystic kidney disease (ADPKD). Recently, a retrospective study showed that the effect of tolvaptan on kidney function could be sustained for a long period. However, the long-term efficacy and safety of high-dose tolvaptan (120 mg/day) in individual cases remain unknown. Read More

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http://dx.doi.org/10.1159/000506118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098338PMC
February 2020

A Case of Frequently Relapsing Minimal-Change Nephrotic Syndrome with Steroid-Induced Psychiatric Syndrome Treated by Low-Dose, Short-Term Steroid Therapy in Combination with Cyclosporine.

Case Rep Nephrol Dial 2020 Jan-Apr;10(1):1-8. Epub 2020 Jan 10.

Department of Nephrology, National Center for Global Health and Medicine, Tokyo, Japan.

Adults with minimal-change nephrotic syndrome (MCNS) generally receive oral prednisolone (PSL) at an initial dosage of 1.0 mg/kg/day for a minimum of 4 weeks, with 80% of patients achieving clinical remission. However, relapses are frequent, necessitating repeated treatment with high-dose PSL. Read More

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http://dx.doi.org/10.1159/000505313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984147PMC
January 2020

Daratumumab for Treatment of Antibody-Mediated Rejection after ABO-Incompatible Kidney Transplantation.

Case Rep Nephrol Dial 2019 Sep-Dec;9(3):149-157. Epub 2019 Nov 13.

Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.

We report the effectiveness of daratumumab, a human IgGκ monoclonal antibody targeting CD38 on plasma cells, for therapy-refractory antibody-mediated rejection (AMR) due to blood group antibodies in a 59-year-old man who received a living ABO-incompatible kidney transplantation. Standard treatment options for AMR due to blood group antibodies including immunoadsorption, lymphocyte depletion with anti-human T-lymphocyte globulins, intravenous methylprednisolone pulses and eculizumab limited tissue injury, however failed to sufficiently suppress blood group antibody production. After administration of daratumumab as a rescue therapy, blood group antibody titers decreased and remained at low levels without further immunoadsorption and allowed kidney graft function to recover. Read More

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http://dx.doi.org/10.1159/000503951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902247PMC
November 2019

Delayed Admission and Management of Pediatric Acute Kidney Injury and Multiple Organ Dysfunction Syndrome in Children with Multiple Wasp Stings: A Case Series.

Case Rep Nephrol Dial 2019 Sep-Dec;9(3):137-148. Epub 2019 Nov 13.

Department of Child Health, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.

Multiple wasp stings may cause fatal complications, such as anaphylactic reactions, intravascular hemolysis, rhabdomyolysis, acute kidney injury (AKI), increased levels of liver enzymes, clotting abnormalities, or even death. AKI-related mortality due to multiple wasp stings may reach 25%, occurring within the early onset of disease; therefore, renal function should be continuously monitored within the first few days following the stings. Herein, we report 2 cases of AKI due to multiple stings of wasp (). Read More

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http://dx.doi.org/10.1159/000504043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902257PMC
November 2019

Donepezil Treatment for Alzheimer's Disease in Chronic Dialysis Patients.

Case Rep Nephrol Dial 2019 Sep-Dec;9(3):126-136. Epub 2019 Sep 5.

First Urology Department, Laiko General Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Donepezil is one of the cholinesterase inhibitors that are indicated for the treatment of mild to moderate Alzheimer's disease (AD). Pharmacokinetic analysis has shown that donepezil is primarily eliminated by renal excretion rather than biliary excretion in humans. Therefore, patients with impaired renal function are at high risk of toxicity caused by accumulation of this drug. Read More

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http://dx.doi.org/10.1159/000502682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787415PMC
September 2019
2 Reads

Gastrointestinal Manifestations in a Patient with Calciphylaxis: A Case Report.

Case Rep Nephrol Dial 2019 May-Aug;9(2):119-125. Epub 2019 Aug 28.

Department of Renal Medicine, Wide Bay Hospital and Health Service, Bundaberg, Queensland, Australia.

Calciphylaxis is a rare condition usually seen in patients with significant renal disease, affecting 1-4' of patients undergoing haemodialysis. Although the disease usually manifests as lesions in the subcutaneous tissue, there have been rare occurrences of calciphylaxis presenting as lesions in the gastrointestinal tract, leading to complications of bowel necrosis and haemorrhage. In view of this, we report the case of suspected gastrointestinal tract calciphylaxis in a 63-year-old patient with end-stage kidney disease (ESKD) who presented with painful swelling in the medial and lateral aspect of both thighs. Read More

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http://dx.doi.org/10.1159/000502436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787423PMC
August 2019
2 Reads

Progressive Renal Dysfunction due to IgG4-Related Kidney Disease Refractory to Steroid Therapy: A Case Report.

Case Rep Nephrol Dial 2019 Jan-Apr;9(1):1-7. Epub 2019 Feb 8.

Division of Nephrology, Department of Internal Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan.

Recently, as the number of case reports of IgG4-related kidney disease (IgG4-RKD) has increased, the histopathological features and clinical approach have been clarified. IgG4-RKD generally has a benign prognosis due to the efficacy of steroid therapy and rarely requires dialysis. Herein, we report a case of IgG4-RKD that presented with a subacute onset, advanced to end-stage kidney disease, and finally required maintenance hemodialysis despite steroid therapy. Read More

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http://dx.doi.org/10.1159/000496465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787412PMC
February 2019
1 Read

Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia.

Case Rep Nephrol Dial 2019 May-Aug;9(2):92-101. Epub 2019 Jul 29.

Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Juntendo University, Tokyo, Japan.

Hereditary renal hypouricemia is characterized by hypouricemia with hyper-uric acid clearance due to a defect in renal tubular transport. Patients with hereditary renal hypouricemia have a higher risk of exercise-induced acute kidney injury (EAKI) and reduced kidney function. Although the best preventive measure is avoiding exercise, there are many kinds of jobs that require occupational exercise. Read More

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http://dx.doi.org/10.1159/000501877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738254PMC
July 2019
1 Read

Three Patients with Lithium-Associated Hyperparathyroidism: Literature Review Regarding Medical and Surgical Management.

Case Rep Nephrol Dial 2019 May-Aug;9(2):108-118. Epub 2019 Aug 20.

UCLA Department of Surgery, Division of Endocrine Surgery, Los Angeles, California, USA.

Lithium (Li) carbonate has been established as a mood stabilizer and an efficacious treatment for bipolar disorder since its discovery by Dr. John Cade in 1948. Li interacts significantly with organ systems and endocrine pathways. Read More

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http://dx.doi.org/10.1159/000502399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751439PMC
August 2019
2 Reads

Faecal Microbiota Transplantation Eradicated Extended-Spectrum Beta-Lactamase-Producing from a Renal Transplant Recipient with Recurrent Urinary Tract Infections.

Case Rep Nephrol Dial 2019 May-Aug;9(2):102-107. Epub 2019 Aug 20.

Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.

Renal transplant recipients (RTRs) are highly susceptible to infections, and antimicrobial resistance is an increasing problem with limited treatment options. Faecal microbiota transplantation (FMT) is effective for recurrent infection and may be used for patients with intestinal carriage of multidrug-resistant (MDR) microorganisms. We present a RTR who suffered from recurrent urinary tract infections (UTIs) caused by extended-spectrum beta-lactamase-producing (ESBL+) . Read More

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http://dx.doi.org/10.1159/000502336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751418PMC
August 2019
1 Read

PLA2R-Negative Membranous Nephropathy Presenting as a Prodrome of IgG4-Related Autoimmune Pancreatitis.

Case Rep Nephrol Dial 2019 May-Aug;9(2):85-91. Epub 2019 Jun 26.

Department of Gastroenterology, Venizeleion Hospital, Heraklion, Greece.

Membranous nephropathy (MN) with tubulointerstitial nephritis (TIN) is an established manifestation of immunoglobulin G4 (IgG4)-related disease (IgG4-RD). A pathological feature aiming to distinguish between primary and secondary MN is the presence or absence of glomerular staining for phospholipase A2 receptor (PLA2R), respectively. Isolated MN without TIN has been rarely reported in the context of IgG4-RD. Read More

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http://dx.doi.org/10.1159/000501260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616050PMC
June 2019
2 Reads

Severe Complications from an Unexpectedly High Serum Mycophenolic Acid Concentration in a Patient with Renal Failure Secondary to Lupus Nephritis: A Case Report.

Case Rep Nephrol Dial 2019 May-Aug;9(2):72-78. Epub 2019 Jun 4.

Shizuoka Children's Hospital, Shizuoka, Japan.

Mycophenolate mofetil (MMF) is used widely to treat lupus nephritis and is considered safer than other immunosuppressive drugs. Reports on severe complications related to MMF are sparse. We report a case of a patient with lupus nephritis in whom severe complications were possibly caused by MMF. Read More

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http://dx.doi.org/10.1159/000500516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587195PMC
June 2019
4 Reads

Postinfectious Glomerulonephritis with Crescents in an Elderly Diabetic Patient after Acute Gastroenteritis: Case Report.

Case Rep Nephrol Dial 2019 May-Aug;9(2):64-71. Epub 2019 May 23.

Department of Medicine, S.M.M.H. Medical College Saharanpur, Saharanpur, India.

Postinfectious glomerulonephritis (PIGN) is primarily a disease of childhood. It occurs after upper respiratory tract infection or skin infections. Streptococcus is the most common causative agent, but in the elderly, staphylococcus is the main culprit. Read More

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http://dx.doi.org/10.1159/000500304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547268PMC
May 2019
8 Reads

IgG4-Related Kidney Disease: A Curious Case of Interstitial Nephritis with Hypocomplementemia.

Case Rep Nephrol Dial 2019 May-Aug;9(2):49-54. Epub 2019 May 16.

Division of Nephrology, University Medicine Cluster, National University Hospital, Singapore, Singapore.

IgG4-related kidney disease has been relatively newly recognized over the last two decades as a combination of an autoimmune and allergic disorder, with elevated serum IgG4 level and hypocomplementemia among its characteristic features. Here we report the case of a man with interstitial nephritis presenting with acute kidney injury and hypocomplementemia but normal serum IgG4 level and provide a literature review of IgG4-related kidney disease. This case highlights the importance of IgG4-related kidney disease as an important differential diagnosis in any patient presenting with a clinical syndrome mimicking acute interstitial nephritis with hypocomplementemia. Read More

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http://dx.doi.org/10.1159/000500296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547283PMC
May 2019
5 Reads

Significance of Crescentic Glomeruli in Acute Kidney Injury with Rheumatoid Arthritis.

Case Rep Nephrol Dial 2019 Jan-Apr;9(1):42-48. Epub 2019 Apr 30.

Division of Nephrology, Allegheny General Hospital, Allegheny Health Network, Drexel University School of Medicine, Pittsburgh, Pennsylvania, USA.

Crescentic glomerulonephritis (GN) without immune reactants or deposits (referred to as pauci-immune) is typically characterized by the presence of anti-neutrophilic cytoplasmic antibodies (ANCA). While ANCA-negative patients might be expected to have a more benign course, they often have poor renal outcomes, especially without treatment with steroids and immune-modulating therapy. Pauci-immune crescentic GN can also co-exist with other autoimmune conditions, including rheumatoid arthritis (RA). Read More

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https://www.karger.com/Article/FullText/500105
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http://dx.doi.org/10.1159/000500105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528077PMC
April 2019
16 Reads

Severe, Symptomatic Hypocalcemia due to Denosumab Administration: Treatment and Clinical Course.

Case Rep Nephrol Dial 2019 Jan-Apr;9(1):33-41. Epub 2019 Apr 23.

Department of Internal Medicine, Mercer University School of Medicine - Savannah Campus, Savannah, Georgia, USA.

Denosumab is a receptor activator of nuclear factor kappa-B (RANK) ligand inhibitor used in the treatment of osteoporosis. Blockade of RANK ligand prevents osteoclastic resorption of bone, but in doing so impairs the parathyroid hormone (PTH)-driven maintenance of serum calcium. A subsequent elevation of PTH remains active at sites other than bone, potentially lowering serum phosphate by inhibiting proximal tubular reabsorption. Read More

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http://dx.doi.org/10.1159/000499824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514500PMC
April 2019
4 Reads

Rapidly Progressive Glomerulonephritis with Delayed Appearance of Anti-Glomerular Basement Membrane Antibody Successfully Treated with Multiple Courses of Steroid Pulse Therapy.

Case Rep Nephrol Dial 2019 Jan-Apr;9(1):25-32. Epub 2019 Apr 16.

Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Patients with anti-glomerular basement membrane (GBM) antibody glomerulonephritis typically exhibit rapidly progressive glomerulonephritis (RPGN). The renal outcome as well as the prognosis of this disease is worse than other forms of RPGN such as those from microscopic polyangiitis. Therefore, early therapeutic intervention is essential to improve its prognosis. Read More

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http://dx.doi.org/10.1159/000499401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514513PMC
April 2019
29 Reads

MPGN Type 3 Associated with Pemphigus Herpetiformis Mimicking PGNMID and Dermatitis Herpetiformis.

Case Rep Nephrol Dial 2019 Jan-Apr;9(1):15-24. Epub 2019 Mar 21.

Department of Nephrology, Juntendo University Faculty of Medicine, Tokyo, Japan.

A 45-year-old man suffering from dermal blistering disease with proteinuria and hematuria underwent renal biopsy. The renal biopsy specimen suggested proliferative glomerulonephritis with monoclonal IgG deposits under routine light, immunofluorescence and electron microscopy. The staining for IgG subclasses (IgG1 and IgG2) and κ/λ light chain indicated secondary immune complex type MPGN type 3. Read More

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https://www.karger.com/Article/FullText/498939
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http://dx.doi.org/10.1159/000498939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465718PMC
March 2019
25 Reads

Monotypic IgG1-kappa Atypical Anti-Glomerular Basement Membrane Nephritis: A Case Report.

Case Rep Nephrol Dial 2019 Jan-Apr;9(1):8-14. Epub 2019 Feb 28.

Division of Academic Affairs and Research, Orlando Regional Healthcare, Orlando, Florida, USA.

Anti-glomerular basement membrane (anti-GBM) glomerulonephritis is a rare disease caused by autoantibodies against the glomerular basement membrane. Atypical anti-GBM nephritis is clinically less aggressive and characterized by the absence of circulating autoantibodies to the basement membrane. A previously healthy 53-year-old white woman presented with a rising creatinine over a short observation period. Read More

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https://www.karger.com/Article/FullText/498844
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http://dx.doi.org/10.1159/000498844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465719PMC
February 2019
8 Reads

Lumbar Artery Bleed as a Complication of Percutaneous Renal Biopsy and a Proposed Workflow for Massive Bleeding.

Case Rep Nephrol Dial 2018 Sep-Dec;8(3):268-276. Epub 2018 Dec 11.

Department of Medicine, National University Health System, Singapore, Singapore.

Injuries to extrarenal arteries caused by percutaneous biopsy needles are very rare but highly lethal due to delay in recognition. Here we report the case of an inadvertent lumbar artery puncture after native renal biopsy and provide a literature review and a proposed workflow for management of massive bleed after renal biopsy. This case highlights evidence-based management considerations regarding massive bleed after renal biopsy, including the first-line imaging modality and the need to consider extrarenal site bleed. Read More

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https://www.karger.com/Article/FullText/495106
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http://dx.doi.org/10.1159/000495106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341319PMC
December 2018
25 Reads

A Case Report of Cronkhite-Canada Syndrome Complicated by Membranous Nephropathy.

Case Rep Nephrol Dial 2018 Sep-Dec;8(3):261-267. Epub 2018 Nov 27.

Division of Nephrology and Hypertension, Mayo Clinic in Arizona, Scottsdale, Arizona, USA.

Cronkhite-Canada syndrome (CCS) is a very rare disorder with less than 500 reported cases. It is characterized by extensive gastrointestinal polyposis and ectodermal anomalies including alopecia, cutaneous hyperpigmentation, and onychodystrophy. Only 3 cases of associated kidney disease (membranous nephropathy [MN]) have been reported. Read More

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https://www.karger.com/Article/FullText/494714
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http://dx.doi.org/10.1159/000494714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323406PMC
November 2018
23 Reads

A Case of Rapid Progressive Kidney Dysfunction with Severely Calcified Stenotic Aorta.

Case Rep Nephrol Dial 2018 Sep-Dec;8(3):253-260. Epub 2018 Nov 27.

Department of Nephrology, Nagano Red Cross Hospital, Nagano, Japan.

Coral reef aorta is rare type of atherosclerotic diseases with severe calcification in the visceral part of the aorta. We present a case of coral reef aorta with severe abdominal aortic stenosis in a 67-year-old man. The patient presented with hypertension, claudication, and rapid progression of renal dysfunction over several months. Read More

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http://dx.doi.org/10.1159/000494716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323407PMC
November 2018
4 Reads

A Case of Self-Limiting Crescentic Immunoglobulin A Glomerulonephritis Associated with Sternoclavicular Arthritis.

Case Rep Nephrol Dial 2018 Sep-Dec;8(3):246-252. Epub 2018 Nov 21.

Division of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Kanagawa, Japan.

Immunoglobulin (Ig) A glomerulonephritis (GN) is a heterogeneous disease affected by various factors. Genetic and other factors "hit" DNA, causing IgA malformation and ultimately glomerular injury. We describe a rare case of crescentic IgA GN with sternoclavicular (SC) arthritis in a 75-year-old woman. Read More

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https://www.karger.com/Article/FullText/494715
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http://dx.doi.org/10.1159/000494715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276760PMC
November 2018
36 Reads

Peritoneal Dialysis Exit Site Pyoderma Gangrenosum: A Case Report.

Case Rep Nephrol Dial 2018 Sep-Dec;8(3):239-245. Epub 2018 Nov 14.

Section of Nephrology, Department of Medicine, Regina, Saskatchewan, Canada.

Background: Pyoderma gangrenosum (PG) is a rare, chronic inflammatory condition exhibiting mucopurulent or hemorrhagic exudates. The majority of cases are associated with inflammatory bowel disease, rheumatological diseases, and hematological malignancies. In the absence of typical serological markers and specific histopathological changes, the diagnosis is often clinical. Read More

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http://dx.doi.org/10.1159/000493188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276769PMC
November 2018
4 Reads

Efficacy of Semiannual Single Fixed Low-Dose Rituximab Therapy in Steroid-Dependent Minimal Change Nephrotic Syndrome: A Case Series.

Case Rep Nephrol Dial 2018 Sep-Dec;8(3):230-237. Epub 2018 Oct 22.

Division of Nephrology, Department of Medicine, Yachiyo Medical Center, Tokyo Women's Medical University, Chiba, Japan.

The frequency of using rituximab to treat refractory nephrotic syndrome has recently been increasing, and the conventional dose of rituximab used to treat it, 375 mg/m body surface area once weekly for 4 weeks, has been modelled on the chemotherapy regimen for B-cell non-Hodgkin's lymphoma. The dose and intervals of rituximab in refractory nephrotic syndrome remain controversial. Clear lymphoma cell hyperplasia is seen in lymphoma patients, but not in nephrotic syndrome patients. Read More

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https://www.karger.com/Article/FullText/493189
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http://dx.doi.org/10.1159/000493189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244099PMC
October 2018
14 Reads

Primary Hyperoxaluria Type 1 with Thrombophilia in Pregnancy: A Case Report.

Case Rep Nephrol Dial 2018 Sep-Dec;8(3):223-229. Epub 2018 Oct 4.

Lehigh Valley Health Network, Allentown, Pennsylvania, USA.

Background: Primary hyperoxaluria type 1 (PH1) is a rare autosomal recessive disease caused by a mutation in the gene, resulting in deficiency of the alanineglyoxylate:aminotransferase enzyme. It is characterized by accumulation of oxalate in the kidneys and other organs.

Case Presentation: A Syrian woman with a history of nephrolithiasis and heterozygosity for factor V Leiden and prothrombin gene mutations presented with postpartum renal failure. Read More

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http://dx.doi.org/10.1159/000493091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206957PMC
October 2018
8 Reads

Bioptically Proven "Anticoagulation-Related Nephropathy" Induced by Dual Antiplatelet Therapy.

Case Rep Nephrol Dial 2018 Sep-Dec;8(3):216-222. Epub 2018 Oct 2.

1st Department of Medicine, Third Faculty of Medicine, Charles University, Prague, Czech Republic.

Anticoagulation-related nephropathy (ARN) is a significant and underdiagnosed complication in patients who receive anticoagulation therapy. It is characterized by acute kidney injury in the setting of excessive anticoagulation defined as an international normalized ratio > 3.0 in patients treated with warfarin. Read More

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https://www.karger.com/Article/FullText/493093
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http://dx.doi.org/10.1159/000493093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206970PMC
October 2018
39 Reads

Bile Cast Nephropathy: A Pathologic Finding with Manifold Causes Displayed in an Adult with Alcoholic Steatohepatitis and in a Child with Wilson's Disease.

Case Rep Nephrol Dial 2018 Sep-Dec;8(3):207-215. Epub 2018 Sep 27.

Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Bile cast nephropathy (BCN) is seen in patients who have acute kidney injury and severe hyperbilirubinemia due to a wide range of hepatobiliary system diseases. Findings seen by renal biopsy include acute tubular injury with necrotic and sloughed epithelial cells, yellow-green pigment within tubular epithelial cells, and pigmented granular casts. Hall's special stain for bile turns these casts green. Read More

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http://dx.doi.org/10.1159/000493231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206956PMC
September 2018
44 Reads

Three Severe Cases of Viral Infections with Post-Kidney Transplantation Successfully Confirmed by Polymerase Chain Reaction and Flow Cytometry.

Case Rep Nephrol Dial 2018 Sep-Dec;8(3):198-206. Epub 2018 Sep 25.

Department of Pediatrics, Kobe University Graduate School of Medicine, Kobe, Japan.

Viral infections in patients with post-kidney transplantation are often difficult to diagnose as well as treat. We herein report three cases with severe viral infections after kidney transplantation. All their causative pathogens could be detected promptly by polymerase chain reaction and flow cytometry during the early stages of infection. Read More

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https://www.karger.com/Article/FullText/493092
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http://dx.doi.org/10.1159/000493092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206958PMC
September 2018
30 Reads

Asymptomatic Lupus Cystitis with Bilateral Hydronephrosis.

Case Rep Nephrol Dial 2018 Sep-Dec;8(3):192-197. Epub 2018 Sep 18.

Department of Internal Medicine, Cipto Mangunkusumo National Teaching Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.

Lupus cystitis is a rare complication of systemic lupus erythematosus (SLE). It is characterized by an increase in bladder wall thickness and may be associated with hydroureteronephrosis. Reports, mostly from East Asian countries, indicate that lupus cystitis usually presents with gastrointestinal tract symptoms such as diarrhea, nausea, or abdominal pain. Read More

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https://www.karger.com/Article/FullText/493090
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http://dx.doi.org/10.1159/000493090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180275PMC
September 2018
31 Reads

Fibrillary Glomerulonephritis with Crescentic and Necrotizing Glomerulonephritis and Concurrent Thrombotic Microangiopathy.

Case Rep Nephrol Dial 2018 May-Aug;8(2):182-191. Epub 2018 Aug 31.

Regina General Hospital, Section of Nephrology, Department of Medicine, Regina, Saskatchewan, Canada.

We present a 77-year-old Caucasian woman who presented with nephrotic-range proteinuria, microhematuria, renal impairment, and extremely elevated blood pressure. She had a long history of well-controlled type 2 diabetes. Renal biopsy revealed fibrillary deposits in the mesangium and glomerular basement membrane consistent with fibrillary glomerulopathy (FGN), with crescentic changes and thrombotic microangiopathy (TMA). Read More

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http://dx.doi.org/10.1159/000492529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167697PMC
August 2018
30 Reads

Minimal Change Nephrotic Syndrome Relapse after 52 Years of Remission: A Case Report.

Case Rep Nephrol Dial 2018 May-Aug;8(2):178-181. Epub 2018 Aug 31.

Department of Nephrology, Hirosaki University Hospital, Hirosaki, Japan.

Minimal change nephrotic syndrome (MCNS) is the most common cause of nephrotic syndrome in children and can also present in adults. Corticosteroids generally induce remission of MCNS, and relapses are common after reduction or discontinuation of corticosteroids. We experienced a rare case of steroid-sensitive MCNS where the patient relapsed after 52 years of remission. Read More

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https://www.karger.com/Article/FullText/492614
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http://dx.doi.org/10.1159/000492614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167670PMC
August 2018
16 Reads

Acute Kidney Injury after Pembrolizumab-Induced Adrenalitis and Adrenal Insufficiency.

Case Rep Nephrol Dial 2018 May-Aug;8(2):171-177. Epub 2018 Aug 10.

Division of Nephrology, Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, California, USA.

Pembrolizumab is an immune checkpoint inhibitor that targets the programmed cell death protein 1 (PD-1) antigen and induces an immune response against tumor tissues. It has been successful in inducing remission in patients with severe metastatic disease, often refractory to other chemotherapeutic agents. The risk of injury of other organ systems has been noted with reported cases of glomerular disease and endocrine disease. Read More

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http://dx.doi.org/10.1159/000491631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120420PMC
August 2018
16 Reads

Case Report: Patient with Hepatitis C, p-ANCA, and Cryoglobulin Antibodies Presenting with Necrotizing Crescentic p-ANCA Glomerulonephritis.

Case Rep Nephrol Dial 2018 May-Aug;8(2):161-170. Epub 2018 Aug 10.

UCLA David Geffen School of Medicine, Westwood, California, USA.

Hepatitis C (HCV) infection has a prevalence of 3 million infected individuals in the United States, according to recent Center for Disease Control reports, and can have various renal manifestations. Cryoglobulins, antibodies that precipitate at colder temperatures in vitro, are a relatively common cause of renal disease in HCV infection. The cryoglobulin proteins can form occlusive aggregates in small glomerular capillary lumina or deposit in other areas of the glomerulus, resulting in hypocomplementemia, proteinuria, hematuria, and renal injury. Read More

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https://www.karger.com/Article/FullText/491629
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http://dx.doi.org/10.1159/000491629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120379PMC
August 2018
14 Reads

Disseminated Strongyloidiasis in Association with Nephrotic Syndrome.

Case Rep Nephrol Dial 2018 May-Aug;8(2):155-160. Epub 2018 Aug 10.

Internal Medicine Residency, Guthrie Robert Packer Hospital, Sayre, Pennsylvania, USA.

Strongyloidiasis is a well-known parasitic infection endemic in tropical and subtropical areas of the world. While most infected individuals are asymptomatic, strongyloidiasis-related glomerulopathy has not been well documented. We present a case of disseminated strongyloidiasis in a patient with minimal change nephrotic syndrome treated with high-dose corticosteroids. Read More

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http://dx.doi.org/10.1159/000491632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120380PMC
August 2018
61 Reads

A Case of Chronic Calcium Oxalate Nephropathy due to Short Bowel Syndrome and Cholecystectomy.

Case Rep Nephrol Dial 2018 May-Aug;8(2):147-154. Epub 2018 Aug 10.

Department of Nephrology, Wakayama Medical University, Wakayama, Japan.

Background: Oxalate nephropathy is a rare disease. Especially chronic oxalate nephropathy still has many unknown aspects as compared to acute oxalate nephropathy with relatively well-known causality.

Case Presentation: The patient was a 70-year-old woman who had a history of small bowel resection 25 years before, cholecystectomy 10 years before, and renal stones (calcium oxalate stones) 7 years before. Read More

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http://dx.doi.org/10.1159/000491630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120416PMC
August 2018
24 Reads

A Rare Case of Severe Metabolic Alkalosis with Unusual Hyperproteinemia Treated with Continuous Renal Replacement Therapy and Regional Citrate Anticoagulation.

Case Rep Nephrol Dial 2018 May-Aug;8(2):138-146. Epub 2018 Aug 3.

Department of Anaesthesiology and Intensive Care, 1st Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.

A 23-year-old woman was referred to the tertiary centre with acute kidney injury and severe metabolic alkalosis following an accidental ethylene glycol poisoning. The patient had been treated with continuous haemodiafiltration and regional citrate anticoagulation, and a tracheostomy was performed due to pneumonia. Besides severe metabolic alkalosis and hypernatremia, the laboratory tests revealed total protein of 108 g/L on admission to the tertiary centre. Read More

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http://dx.doi.org/10.1159/000491628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120368PMC
August 2018
4 Reads

Acute Kidney Failure as a Single Complication of Varicella Virus Infection in an Adult Patient.

Case Rep Nephrol Dial 2018 May-Aug;8(2):130-137. Epub 2018 Aug 3.

Department of Nephrology, Hypertension, Dialysis, and Transplantation, University Hospital Center Zagreb, Zagreb, Croatia.

Background: Varicella zoster virus (VZV) is distributed worldwide and is highly contagious. In adults and immunosuppressed patients of any age, the clinical course is much more severe. The most severe complications are pneumonia (the main cause of lethal outcomes in this infection), encephalitis, and very rarely Reye syndrome and hepatitis. Read More

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http://dx.doi.org/10.1159/000491627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120375PMC
August 2018
5 Reads

Salvage of Hemodialysis Catheter in Staphylococcal Bacteremia: Case Series, Revisiting the Literature, and the Role of the Pharmacist.

Case Rep Nephrol Dial 2018 May-Aug;8(2):121-129. Epub 2018 Jul 25.

Philadelphia College of Pharmacy, University of the Sciences, Philadelphia, Pennsylvania, USA.

Catheter-related blood stream infections comprise a major concern in hemodialysis patients, leading to increased mortality, morbidity, and cost of treatment. Prompt appropriate systemic antibiotics treatment, which includes administration of appropriate systemic antibiotics and, frequently, catheter removal and replacement, is warranted. However, in hemodialysis patients, repeated catheter insertions may cause central vein stenosis and thrombosis which limits the future availability of hemodialysis access. Read More

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https://www.karger.com/Article/FullText/489923
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http://dx.doi.org/10.1159/000489923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103365PMC
July 2018
9 Reads

Postembolization Intratumoral Chronic Bleeding, without the Classic CT Feature of Active Extravasation, in Tuberous Sclerosis Complex-Related Renal Angiomyolipoma: Two Case Reports.

Case Rep Nephrol Dial 2018 May-Aug;8(2):112-119. Epub 2018 Jun 8.

Department of Radiology, School of Medicine, Juntendo University, Tokyo, Japan.

Two patients with tuberous sclerosis complex each had multiple bilateral renal angiomyolipomas. After undergoing embolization for a ruptured angiomyolipoma, patient 1 experienced long-lasting abdominal fullness; contrast-enhanced computed tomography (CECT) revealed a large chronic hematoma without contrast extravasation. Patient 2 underwent embolization for the largest right renal angiomyolipoma which contained a chronic hematoma. Read More

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http://dx.doi.org/10.1159/000489924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031947PMC
June 2018
3 Reads

Importance of AST-120 (Kremezin®) Adherence in a Chronic Kidney Disease Patient with Diabetes.

Case Rep Nephrol Dial 2018 May-Aug;8(2):107-111. Epub 2018 Jun 8.

Shinjuku Minamiguchi Clinic, Medical Corporation Showakai, Tokyo, Japan.

We report herein an adult case of chronic kidney disease (CKD) associated with diabetes. The patient had been treated with insulin injection for diabetes 10 years ago. At the time of his first visit to our division for further examinations, we diagnosed him as CKD: cause (C) diabetes; glomerular filtration rate (GFR) (G) G5 (estimated [e] GFR, 10. Read More

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https://www.karger.com/Article/FullText/489772
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http://dx.doi.org/10.1159/000489772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031942PMC
June 2018
88 Reads

The Unpredictability of Idiopathic Membranous Nephropathy: An Illustrative Case Report.

Case Rep Nephrol Dial 2018 May-Aug;8(2):103-106. Epub 2018 Jun 1.

Division of Nephrology/Hypertension, Department of Medicine, Northwestern University Feinberg School of Medicine and Northwestern Memorial Hospital, Chicago, Illinois, USA.

The case of a female patient with primary membranous nephropathy is presented. She was treated with corticosteroids and chlorambucil after conservative therapy had failed and went into remission for 5 years. Her nephrotic syndrome recurred but did not respond to the same regimen. Read More

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https://www.karger.com/Article/FullText/489773
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http://dx.doi.org/10.1159/000489773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006632PMC
June 2018
7 Reads

Bile Cast Nephropathy: The Unknown Dangers of Online Shopping.

Case Rep Nephrol Dial 2018 May-Aug;8(2):98-102. Epub 2018 May 31.

Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.

Renal dysfunction in the setting of cholestatic liver disease is multifactorial but most often due to decreased kidney perfusion from intravascular volume depletion, acute tubular injury/necrosis, and hepatorenal syndrome. Drug-induced hepatotoxicity may be associated with a cholestatic injury pattern. We report a case of a 56-year-old man with a diagnosis of bile cast nephropathy, as a complication of drug-induced severe hyperbilirubinemia due to the abuse of intramuscular anabolic steroids bought on the internet to increase muscular mass for bodybuilding training. Read More

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http://dx.doi.org/10.1159/000489771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006645PMC
May 2018
8 Reads

The Case: Chronic Kidney Disease Unmasked by Single-Subject Research.

Case Rep Nephrol Dial 2018 May-Aug;8(2):90-97. Epub 2018 May 16.

Experimental and Clinical Research Center (ECRC), Berlin, Germany.

We present a 42-year-old man with a BMI of 32, who was referred because of proteinuria and decreased renal function. We were impressed by his markedly muscular physique. A renal biopsy was performed, which showed focal segmental glomerular sclerosis (FSGS). Read More

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http://dx.doi.org/10.1159/000489087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006620PMC
May 2018
17 Reads