1,206 results match your criteria Case reports in gastroenterology[Journal]


Enoxaparin-Induced Liver Injury.

Case Rep Gastroenterol 2020 May-Aug;14(2):315-319. Epub 2020 Jun 10.

Department of Gastroenterology, Bronx Care Health System, Bronx, New York, USA.

Enoxaparin, a form of low-molecular-weight heparin, can cause a rare, underreported, and often reversible form of hepatocellular injury. This report describes a case of enoxaparin-induced hepatotoxicity in a 61-year-old male diagnosed with pulmonary embolism. Elevations of liver enzymes were noted within 1 week of starting the drug, followed by a dramatic improvement upon its discontinuation, with subsequent normalization in the following days. Read More

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http://dx.doi.org/10.1159/000508471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315174PMC

Groove Pancreatitis Associated with Transient Liver Injury Mimicking Ampullary Neoplasm.

Case Rep Gastroenterol 2020 May-Aug;14(2):306-314. Epub 2020 Jun 2.

Department of Hematology and Oncology, Hamad Medical Corporation, Doha, Qatar.

Groove pancreatitis is an unusual form of pancreatitis characterized by fibrous inflammation and pseudo-tumor in the area around the head of the pancreas. The underlying etiology is unknown but is strongly linked to alcohol abuse. We report a 52-year-old male smoker with hypertension, asthma, and alcohol abuse who was admitted with severe epigastric pain radiating to the back. Read More

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http://dx.doi.org/10.1159/000507430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315138PMC

Synchronous Hepatocellular Carcinoma in a Patient with Primary Gastric Cancer: An Exceptional Association.

Case Rep Gastroenterol 2020 May-Aug;14(2):299-305. Epub 2020 May 28.

Department of Gastroenterology, Faculty of Medicine, Ibn Al Jazzar, University Hospital of Sahloul, Sousse, Tunisia.

Hepatocellular carcinoma (HCC) is the most frequent type of liver cancer. Liver cirrhosis of any etiology is considered the main risk factor for the development of HCC. However, HCC in noncirrhotic livers remains an uncommon finding. Read More

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http://dx.doi.org/10.1159/000506188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315167PMC

Factitious Disorder Presenting with Refractory Enterocutaneous Fistula that Underwent 7 Surgeries.

Case Rep Gastroenterol 2020 May-Aug;14(2):291-298. Epub 2020 May 27.

Department of Colorectal Disease, The No.10 People's Hospital of Shanghai, Shanghai, China.

The formation of a post-appendicectomy fistula is rare but devastating. Major etiological factors include leakage from the appendiceal stump, neoplasm of the appendix and/or cecum, infection, inflammatory bowel disease, and distal obstruction. The management of enterocutaneous fistula involves enteral nutrition, drainage, antibiotic coverage, as well as surgical excision and segmental resection of the involved bowel. Read More

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http://dx.doi.org/10.1159/000506936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315171PMC

Sigmoid Volvulus with Widespread Bowel Ischemia after Endoscopic Reduction Successfully Treated with Elective Laparoscopic Surgery.

Case Rep Gastroenterol 2020 May-Aug;14(2):286-290. Epub 2020 May 13.

Department of Surgery, Kishiwada Tokushukai Hospital, Kishiwada, Japan.

An 87-year-old man complaining of abdominal distention was referred to our hospital. Plain radiograph and enhanced computed tomography (CT) showed a dilated sigmoid colon with a coffee bean sign, leading to the diagnosis of sigmoid volvulus. Based on symptoms and the CT and laboratory test findings, we initially treated the patient with endoscopic reduction, resulting in successful reduction of the sigmoid volvulus with widespread presumed mucosal ischemia. Read More

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http://dx.doi.org/10.1159/000507611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265717PMC

Cytomegalovirus Colitis with a Cobblestone Appearance.

Case Rep Gastroenterol 2020 May-Aug;14(2):279-285. Epub 2020 May 13.

Department of Gastroenterology, National Hospital Organization Hakodate National Hospital, Hakodate, Japan.

Cytomegalovirus (CMV) colitis with a cobblestone appearance is rare, and its endoscopic and pathological features remain poorly described. A 78-year-old woman was admitted to our hospital for disturbance of consciousness, high-grade fever, and diarrhea occurring up to 7 times a day. Sigmoidoscopy revealed a circumferential ulcer with mucosal defect, an ulcer with a cobblestone appearance extending from the upper rectum to the sigmoid colon, and an irregular ulcer on the lower rectum. Read More

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http://dx.doi.org/10.1159/000507649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265724PMC

Massive Hepatomegaly Secondary to Amyloidosis with Normal Liver Chemistries.

Case Rep Gastroenterol 2020 May-Aug;14(2):271-278. Epub 2020 May 13.

WWAMI Medical Education Program and Department of Biological Sciences, University of Idaho, Moscow, Idaho, USA.

Amyloid light chain (AL) amyloidosis is a disease of misfolded, fibrous proteins, either kappa or lambda subtype, that can be deposited into one or more organs, caused by a proliferation of plasma cells. The liver is uncommonly the main organ system affected and rarely the only organ affected by amyloid deposition. With hepatic involvement, the most common presenting findings are hepatomegaly and elevation of serum alkaline phosphatase. Read More

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http://dx.doi.org/10.1159/000507612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265701PMC

Over-the-Scope Clip to the Rescue! A Novel Tool for Refractory Acute Nonvariceal Upper Gastrointestinal Hemorrhage.

Case Rep Gastroenterol 2020 May-Aug;14(2):261-270. Epub 2020 May 12.

Department of Gastroenterology, Staten Island University Hospital, Northwell Health, Staten Island, New York, USA.

Nonvariceal upper gastrointestinal hemorrhage (NVUGIH) is more prevalent than lower gastrointestinal hemorrhage and carries a high risk of mortality in the elderly, especially those with significant cardiovascular comorbidities. Traditional endoscopic methods, such as through-the-scope clips, electrocautery, and epinephrine injection, are frequently used to control these bleeds; however, they carry a 10% risk of rebleeding, and this itself carries a mortality risk of 36%. The larger over-the-scope clips (OTSC) that were initially used for the closure of fistulas and perforations are now gradually being implemented to manage NVUGIH. Read More

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http://dx.doi.org/10.1159/000507610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265719PMC

Fatal Spontaneous Tumor Lysis Syndrome in a Patient with Metastatic Colon Cancer: A Clinical Case of Rare Oncological Emergency.

Case Rep Gastroenterol 2020 May-Aug;14(2):255-260. Epub 2020 May 7.

Department of Internal Medicine, Hospital Harzklinikum Dorothea Christiane Erxleben GmbH, Wernigerode, Germany.

Tumor lysis syndrome (TLS) is a potentially life-threatening complication of chemotherapy. It usually occurs in rapidly proliferating hematological malignancies. TLS is deemed spontaneous (STLS) when it occurs prior to any cytotoxic or definite treatment. Read More

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http://dx.doi.org/10.1159/000507648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250380PMC

Ultimate Stomaless Technique of Two-Stage Operation for Lower Rectal Cancer Performed on a Patient with a High Body Mass Index: The Reborn Operation (Novel Pull-Through Method).

Case Rep Gastroenterol 2020 Jan-Apr;14(1):248-254. Epub 2020 Apr 29.

Division of Surgery, Gastroenterological Center, Medico Shunju Shiroyama Hospital, Osaka, Japan.

A 58-year-old Japanese man, with a body mass index of 41.7 kg/m2 (height: 179.8 cm; weight: 133. Read More

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http://dx.doi.org/10.1159/000507076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252201PMC

Amoxicillin-Clavulanate-Induced Ischaemic Colitis.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):242-247. Epub 2020 Apr 29.

Gastroenterology Unit, Department of Clinical and Experimental Sciences, University of Brescia and Spedali Civili, Brescia, Italy.

Ischaemic colitis (IC) is the most frequent form of ischaemia of the digestive tract. Due to the worldwide increasing use of medications, there is a growing interest in drug-induced IC. This study reports a rare case of IC directly due to amoxicillin-clavulanate intake. Read More

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http://dx.doi.org/10.1159/000507014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250379PMC

Porta Hepatis Injury during Laparoscopic Cholecystectomy.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):234-241. Epub 2020 Apr 28.

Department of General Surgery, Al-Assad University Hospital, Faculty of Medicine, Damascus University, Damascus, Syrian Arab Republic.

Iatrogenic porta hepatis injury is a rare but devastating surgical complication of laparoscopic cholecystectomy. There are no systematic studies examining the best treatment strategy in patients with this injury. We present a case of a 23-year-old woman with a large abscess in the right hepatic lobe due to an extreme vasculobiliary injury after laparoscopic cholecystectomy. Read More

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http://dx.doi.org/10.1159/000507431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204780PMC

Unresectable Ectopic Hepatocellular Carcinoma Treated with Sorafenib.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):226-233. Epub 2020 Apr 27.

Department of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.

Ectopic hepatocellular carcinoma (HCC) is a rare malignancy, which manifests similar morphology and immunohistochemistry to intrahepatic HCC. Herein, we report a case of ectopic HCC in a 73-year-old male. The patient presented to our hospital with gradually progressing right lower abdominal pain, and enhanced computed tomography revealed multiple nodules in the peritoneum without intrahepatic mass. Read More

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http://dx.doi.org/10.1159/000506929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204886PMC

Severe Postoperative Chronic Constipation Related to Anorectal Malformation Managed with Osteopathic Manipulative Treatment.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):220-225. Epub 2020 Apr 27.

Department of Clinical Pediatrics, Manima Not-for-Profit Healthcare and Assistance, Milan, Italy.

Constipation is frequent amongst infants who have undergone surgery for anorectal malformation (ARM). Faecal retention, due to a dysfunctional enteric reflex of defaecation, can cause abdominal cramps, pseudoincontinence and, in the worst cases, megacolon. Prokinetic protocols are used to stimulate at least 1 bowel movement per day, including laxatives, enema, stools softeners and dietary schedules. Read More

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http://dx.doi.org/10.1159/000506937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204772PMC

Laparoscopic Splenectomy in a Patient with Sclerosing Angiomatoid Nodular Transformation.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):212-219. Epub 2020 Apr 22.

Department of Diagnostic Pathology, Omura Municipal Hospital, Omura, Japan.

Sclerosing angiomatoid nodular transformation (SANT) of the spleen is a specific, tumor-forming, non-neoplastic, vascular lesion with few reported cases worldwide. Herein, we describe the case of a patient who underwent laparoscopic splenectomy for SANT. A 47-year-old woman underwent upper gastrointestinal endoscopy for suspected gastric submucosal tumor. Read More

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http://dx.doi.org/10.1159/000506934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204771PMC

Cecal Volvulus: A Rare Cause of Intestinal Obstruction.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):206-211. Epub 2020 Apr 22.

Hepato-Pancreato-Biliary Unit, Department of General Surgery, Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico.

Cecal volvulus is a rare cause of intestinal obstruction, with multifactorial etiologies. This is a case report describing a 52-year-old female with a cecal volvulus diagnosis made during the laparotomy procedure, which was treated with a right hemicolectomy with a side-to-side ileotransverse anastomosis. The aim of this report is to emphasize the importance of a diagnosis and appropriate treatment in this rare pathology in abdominal procedures. Read More

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http://dx.doi.org/10.1159/000506933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204782PMC

Rapidly Growing Desmoid-Type Fibromatosis of the Mesentery of the Small Intestine after Distal Gastrectomy for Gastric Cancer.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):197-205. Epub 2020 Apr 21.

Department of Gastrointestinal Surgery, Hokkaido Cancer Center, Sapporo, Japan.

We report the case of a 55-year-old man with a surgical history of distal gastrectomy with Roux-en-Y reconstruction performed 3 years prior to the present episode. During the follow-up, a newly developed, rapidly growing intraabdominal mass was detected in the mesentery of the small intestine. Although the patient had been asymptomatic, surgical resection was planned with the suspicion of malignancy, especially lymph node recurrence of the gastric cancer, owing to its rapid growth. Read More

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http://dx.doi.org/10.1159/000506926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204778PMC

A Rare Presentation of Poorly Differentiated Lung Carcinoma with Duodenal Metastasis and Literature Review.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):186-196. Epub 2020 Apr 21.

Gastroenterology and Hepatology, East Orange Department of Veteran's Affair, East Orange, New Jersey, USA.

Lung cancer is a common malignancy which is frequently found to metastasize to distant sites including bone, liver, and adrenal glands. There are rare reports of metastases to the gastrointestinal (GI) tract, with the duodenum being the most uncommon. We present a rare case of a poorly differentiated lung carcinoma metastasizing to the duodenum. Read More

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http://dx.doi.org/10.1159/000506927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204736PMC

Oropharyngeal Candidiasis as a Presenting Symptom of Crohn's Disease.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):178-185. Epub 2020 Apr 17.

Department of Pathology, Hamad General Hospital, Hamad Medical Corporation Qatar, Doha, Qatar.

Oropharyngeal candidiasis is a common condition in immunosuppressed patients. Inflammatory bowel disease (IBD) is a prevalent medical condition which commonly presents with intestinal and extra intestinal manifestations. Crohn's disease (CD) tends to present more with extraintestinal symptoms. Read More

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http://dx.doi.org/10.1159/000506931DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204888PMC

Ferrous Sulfate-Induced Esophageal Injury Leading to Esophagitis Dissecans Superficialis.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):172-177. Epub 2020 Apr 17.

Division of Gastroenterology, Department of Medicine, Rutgers, New Jersey Medical School, Newark, New Jersey, USA.

Medication-induced esophagitis is a well-known but relatively rare clinical diagnosis, most common in patients with preexisting esophageal dysmotility, obstruction, or altered anatomy. Esophagitis dissecans superficialis (EDS) is a rare endoscopic finding characterized by sloughing of large fragments of the esophageal mucosal lining. The causes of EDS include prior trauma, heavy smoking history, ingestion of alcoholic and hot beverages, and immunosuppression. Read More

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http://dx.doi.org/10.1159/000506935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204857PMC

Pyogenic Liver Abscess Secondary to Sigmoid Diverticulitis: An Unusual Presentation.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):165-171. Epub 2020 Apr 17.

Southmead Hospital, North Bristol Trust, Bristol, United Kingdom.

Pyogenic liver abscesses, despite being a rare complication of diverticulitis and inflammatory bowel disease, are potentially serious life-threatening pathologies. Diverticular diseases can lead to disruption of the colonic mucosal barrier and can serve as a route for bacterial infection via the portal venous system. This patient had such a delayed presentation due to his atypical symptoms; he developed large abscess formation, detected by computed tomography, eventually requiring an ultrasound-guided drain followed by a colonoscopy. Read More

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http://dx.doi.org/10.1159/000506932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204770PMC

Endocytoscopic Observation of Non-Ampullary Mucosal Duodenal Cancer.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):156-164. Epub 2020 Apr 14.

Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan.

Our previous study of duodenal adenoma using an endocytoscopy system (ECS) demonstrated that disappearance of goblet cells and spindle-shaped nuclei with loss of polarity were characteristic features. In addition, round duct openings and finger-like projections were observed in tubular adenoma and villous adenoma, respectively. Here, we retrospectively investigated six cases of histologically proven sporadic non-ampullary mucosal duodenal cancer (NAMDC) using ECS. Read More

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http://dx.doi.org/10.1159/000506930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184857PMC

Colonic Diverticular Bleeding Associated with Bowel Cleansers before Colonoscopy.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):150-155. Epub 2020 Apr 8.

Department of Gastroenterology, National Hospital Organization, Hakodate National Hospital, Hakodate, Japan.

To date, colonic diverticular bleeding associated with bowel cleansers has not been reported, and its endoscopic and pathological features remain largely unclear. We report a case of colonic diverticular bleeding associated with a bowel cleanser (137 g of polyethylene glycol [NIflec®]) before colonoscopy (CS). CS revealed colonic diverticular bleeding in the sigmoid colon. Read More

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http://dx.doi.org/10.1159/000507015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184855PMC

Primary Hepatic Angiosarcoma: A Rare Liver Malignancy - Varying Manifestations but Grave Prognosis.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):137-149. Epub 2020 Apr 8.

Gastroenterology and Hepatology Unit, Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.

Primary hepatic angiosarcoma (PHA) is a rare mesenchymal liver tumor, accounting for 0.1-2% of primary liver malignancies. The clinical presentations of PHA are variable, from asymptomatic to liver failure or complicated with tumor rupture. Read More

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http://dx.doi.org/10.1159/000506928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184854PMC

Spontaneous Resolution of Hemorrhagic Pseudocyst-Associated Pseudoaneurysm in Groove Pancreatitis.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):131-136. Epub 2020 Apr 8.

Department of Internal Medicine, Konkuk University Chungju Hospital, Chungju, Republic of Korea.

Hemorrhagic pseudocyst (HP) and pseudocyst-associated pseudoaneurysms (PPs) are complications of pseudocyst. Angiography with embolization has been advocated as the first-line intervention for HP. A 47-year-old man with groove pancreatitis combined with HP near the pancreatic head was treated conservatively. Read More

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http://dx.doi.org/10.1159/000502836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184797PMC

Clinicopathology and Diagnosis Delay in a 40-Year-Old with Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE).

Case Rep Gastroenterol 2020 Jan-Apr;14(1):124-130. Epub 2020 Apr 2.

Department of Gastroenterology, Saint George Hospital University Medical Center, Beirut, Lebanon.

Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an autosomal recessive and fatal multisystem metabolic disorder. It presents with wide-ranging gastrointestinal and neurologic symptoms. It is caused by a mutation in the TYMP gene which impairs thymidine phosphorylase (TP) activity, therefore leading to the accumulation of thymidine and deoxyuridine in plasma and tissues. Read More

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http://dx.doi.org/10.1159/000506187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184788PMC

Minor Papillary Relief in a Type IA Choledochal Cyst: A Case Report and Review of the Literature.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):116-123. Epub 2020 Apr 2.

Department of Gastroenterology and Hepatology, The Brooklyn Hospital Center, Affiliate of The Icahn School of Medicine at Mount Sinai, Brooklyn, New York, USA.

Choledochal cysts are an anatomical conundrum as they present with nonspecific symptoms generally delaying diagnosis and treatment. Its lag time remains critical, as cholangiocarcinoma, a fatal sequelae, contributes to its morbidity and mortality. Herein, we present a case of a type 1A choledochal cyst. Read More

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http://dx.doi.org/10.1159/000506226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184792PMC

Identifying Cystic Vein Perfusion Area Employing Indocyanine Green Fluorescence Imaging during Laparoscopic Extended Cholecystectomy for Clinical T2 Gallbladder Cancer.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):110-115. Epub 2020 Feb 25.

Department of Surgery, Iwate Medical University, Yahaba, Japan.

We present an original surgical technique for identifying the perfusion area of the cystic vein with indocyanine green (ICG) fluorescence imaging and laparoscopic extended cholecystectomy with lymphadenectomy for a 56-year-old woman with diagnosis of clinical T2 gallbladder cancer (GBC). First, we encircled Calot's triangle using the Glissonean approach from the ventral side of the gallbladder plate and then taped the hilar Glissonean pedicles; these were temporally clamped, and ICG was injected into the vein. The perfusion area of the cystic vein was scrutinized, specifically the stained area of the hepatic parenchyma was marked, and extended cholecystectomy was performed along the resection line. Read More

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http://dx.doi.org/10.1159/000506361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098343PMC
February 2020

Cytomegalovirus Enterocolitis in a Patient with Refractory Immune-Related Colitis.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):103-109. Epub 2020 Feb 25.

Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

Although most immune-related adverse events (irAEs) secondary to immune checkpoint inhibitors can be managed with immunosuppressive therapies; they can induce reactivation of infectious diseases, including cytomegalovirus (CMV). Here, we show a case of CMV enterocolitis during steroid therapy for an irAE. A 77-year-old man with unresectable malignant melanoma was treated with ipilimumab. Read More

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http://dx.doi.org/10.1159/000506186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098339PMC
February 2020

Multidisciplinary Treatment of Advanced Hepatocellular Carcinoma.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):98-102. Epub 2020 Feb 21.

Department of Hepatobiliary and Pancreatic Surgery, Shulan (Hangzhou) Hospital, Hangzhou, China.

Current strategy for treatment of hepatocellular carcinoma (HCC) based on Barcelona-Clinic Liver Cancer (BCLC) criteria dictates that patients with advanced-stage HCC are to only receive treatment with tyrosine kinase inhibitors. However, they prolong overall survival just by slightly more than 6 months. In this article, we present a patient with HCC diagnosed at an advanced stage who received multidisciplinary treatment consisting of transarterial chemoembolization, hepatic resection, pulmonary resection, radiofrequency ablation, tyrosine kinase inhibitors, and radiotherapy, and has survived for more than 2 years since diagnosis and counting. Read More

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http://dx.doi.org/10.1159/000506185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098351PMC
February 2020

Right Hemihepatectomy via an Anterior Approach for Hepatocellular Carcinoma in a Situs Inversus Totalis Patient.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):91-97. Epub 2020 Feb 20.

Department of Hepatic Surgery, the Affiliated Foshan Hospital of Sun Yat-sen University, Foshan, China.

Situs inversus totalis (SIT) is a rare congenital condition in which the usual position of the organs is reversed from left to right as a mirror image of the normal situation. Due to the abnormal transposition, this represents a technical challenge for the surgeon. In the present study, right hemihepatectomy via the anterior approach was performed for a 68-year-old hepatocellular carcinoma (HCC) patient with SIT. Read More

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http://dx.doi.org/10.1159/000506183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098364PMC
February 2020

Amiodarone-Induced Acute Liver Injury.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):87-90. Epub 2020 Feb 20.

Department of Internal Medicine, Geisinger Medical Center, Danville, Pennsylvania, USA.

Amiodarone is a lipophilic structure with a half-life of 25-100 days. Long-term oral amiodarone is associated with photosensitivity, thyroid dysfunction, and pulmonary and hepatic toxicity. Intravenous amiodarone can lead to sweating, heating sensation, nausea, phlebitis at the injection site, and rarely acute hepatitis. Read More

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http://dx.doi.org/10.1159/000506184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098330PMC
February 2020

Endoscopic Retrograde Cholangiopancreatography Leading to Pharyngeal Perforation.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):80-86. Epub 2020 Feb 20.

Division of Gastroenterology, Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USA.

Endoscopic retrograde cholangiopancreatography (ERCP) had become the favored method to access the pancreaticobiliary system because it is a safer and less invasive method compared to surgery. However, as with any procedure, ERCP comes with its own risks and potential complications. We present a unique case of a patient who underwent ERCP and developed necrotizing infection of the neck and a submandibular abscess. Read More

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http://dx.doi.org/10.1159/000506182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098341PMC
February 2020

Hemospray® during Emergency Endoscopy: Indonesia's First Experience from 37 Patients.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):70-79. Epub 2020 Feb 6.

Division of Gastroenterohepatology, Department of Internal Medicine, Hasan Sadikin General Hospital-Faculty of Medicine, University of Padjadjaran, Bandung, Indonesia.

Gastrointestinal bleeding (GIB) is one of the main indications for performing endoscopy; this condition can be life threatening. In some cases, emergency endoscopy (EE) is necessary to identify the source and stop the bleeding. Recently, hemostatic powder was introduced, one of which was Hemospray® (Cook Medical, Winston-Salem, NC, USA), which showed promising results for rapid hemostasis in primary treatment and salvage when conventional methods fails. Read More

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http://dx.doi.org/10.1159/000505775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036561PMC
February 2020

Perforation of the Small Intestine after Introduction of Lenvatinib in a Patient with Advanced Hepatocellular Carcinoma.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):63-69. Epub 2020 Feb 5.

Department of Gastroenterology, Toyama University Hospital, Toyama, Japan.

Lenvatinib is a first-line standard treatment for advanced hepatocellular carcinoma (HCC) with better anti-tumor effects than sorafenib, as shown by greater inhibition of the kinases of fibroblast growth factor receptor and vascular endothelial growth factor (VEGF) receptor. This report describes a patient with advanced HCC who experienced perforation of the small intestine 1 month after starting the treatment with lenvatinib. This patient likely had partial necrosis of a metastasis to the small intestine before starting lenvatinib treatment, with subsequent ischemic changes leading to perforation of the small intestine. Read More

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http://dx.doi.org/10.1159/000505774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036537PMC
February 2020

Hepatic Epithelioid Hemangioendothelioma: Difficult Differential Diagnosis from Angiosarcoma.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):56-62. Epub 2020 Jan 29.

Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.

Hepatic epithelioid hemangioendothelioma (EHE) is extremely rare, and preoperative diagnosis is difficult because hepatic EHE has clinicopathological features that are similar to those of angiosarcoma. However, it is important to differentiate hepatic EHE from angiosarcoma because the latter is an aggressive tumor with poor prognosis. We herein report a case of hepatic EHE that was difficult to distinguish from angiosarcoma by tumor biopsy. Read More

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http://dx.doi.org/10.1159/000505513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036556PMC
January 2020

Peroral Endoscopic Myotomy in a Patient with Achalasia Cardia with Prior Heller's Myotomy.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):48-55. Epub 2020 Jan 22.

Asian Institute of Gastroenterology, Hyderabad, India.

Achalasia cardia is an esophageal myenteric plexus disorder characterized by absence of or incomplete lower esophageal sphincter relaxation and esophageal aperistalsis; Heller's myotomy is the main treatment of choice due to a lower failure rate. Recently, peroral endoscopic myotomy (POEM) has been reported as an alternative treatment for achalasia due to persistent symptoms after Heller's myotomy. An Indian male, aged 18 years, was admitted to the hospital due to dysphagia which had started more than 3 years ago. Read More

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http://dx.doi.org/10.1159/000505512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011739PMC
January 2020

An Epileptic Patient with Recurrent Hyperbilirubinemia Caused by Gilbert Syndrome.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):39-47. Epub 2020 Jan 22.

Department of Neurology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

Gilbert syndrome (GS) is characterized by intermittent indirect bilirubin elevation. Several antiepileptic drugs (AEDs) impair the liver function to different degrees, such as valproic acid, lamotrigine, phenobarbital, phenytoin, and carbamazepine. Herein, we present the case of a 26-year-old epileptic patient with frequently recurring mild hyperbilirubinemia during taking AEDs. Read More

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http://dx.doi.org/10.1159/000504645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011721PMC
January 2020

Endoscopic Treatment of Solitary Colonic Ganglioneuroma.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):34-38. Epub 2020 Jan 20.

Department of Gastroenterology, Hashimoto Municipal Hospital, Hashimoto, Japan.

Ganglioneuromas (GNs) in adults are uncommon clinical entities, especially in the colon. Patients with GNs without multiple endocrine neoplasia or neurofibromatosis-I are normally asymptomatic; however, GNs can present with abdominal pain, weight loss, bleeding, and anemia, depending on the size and location. Here, we present a case of solitary colonic GN treated with endoscopic mucosal resection. Read More

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http://dx.doi.org/10.1159/000505510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011718PMC
January 2020

"Obscure" Appendiceal Orifice Polyps Can Be Challenging to Identify by Colonoscopy.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):15-26. Epub 2020 Jan 20.

Department of Medicine, St. Luke's Hospital, Chesterfield, Missouri, USA.

The primary purpose of screening colonoscopy is the detection and subsequent removal of precancerous polyps. However, effective recognition of appendiceal lesions with a standard endoscope is often challenging and is limited to the base of the cecum and appendiceal orifice. The majority of appendiceal polyps are found incidentally following an appendectomy, though rarely they may be discovered during a colonoscopy. Read More

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http://dx.doi.org/10.1159/000505482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011709PMC
January 2020

Rectal Arteriovenous Malformation Treated by Transcatheter Arterial Embolization.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):7-14. Epub 2020 Jan 20.

Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

An 86-year-old man who presented with frequent hematochezia with mild anemia on blood tests was admitted to our hospital. Colonoscopy exhibited a submucosal tumor-like lesion in the lower rectum. CT and MRI showed blood flow into the lesion, but not tumor component. Read More

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http://dx.doi.org/10.1159/000505090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011768PMC
January 2020

Early Postendoscopic Transverse Colo-Colonic Intussusception.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):1-6. Epub 2020 Jan 3.

Department of Gastroenterology, NYU Winthrop University Hospital, Mineola, New York, USA.

Intussusception is defined as telescoping of the proximal bowel (intussusceptum) into the lumen of the distal bowel, otherwise called the intussuscipiens. While it is one of the most common causes of intestinal obstruction in children between the ages of 3 months and 6 years, intussusception accounts for about 1% of such cases in adults. Intussusception is idiopathic in 8-20% of patients and most commonly occurs in the small intestines in adults. Read More

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http://dx.doi.org/10.1159/000505228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984140PMC
January 2020

A Progressive Huge Accessory Spleen in the Greater Omentum.

Case Rep Gastroenterol 2019 Sep-Dec;13(3):539-543. Epub 2019 Dec 19.

Department of Coloproctological Surgery, Faculty of Medicine, Juntendo University, Tokyo, Japan.

Huge accessory spleen (AS) is a rare condition difficult to diagnose. We recently treated a Japanese woman with a progressive huge AS. She had a history of aortic valve replacement for aortic stenosis 1 month prior. Read More

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http://dx.doi.org/10.1159/000504433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959113PMC
December 2019

Linked Color Imaging Highlights Flat Early Gastric Cancer.

Case Rep Gastroenterol 2019 Sep-Dec;13(3):532-538. Epub 2019 Dec 12.

Department of Gastroenterology, National Hospital Organization Hakodate National Hospital, Hakodate, Japan.

While linked color imaging (LCI) may allow flat early gastric cancer to be detected early, the endoscopic and pathological features of lesions detected by LCI remain poorly described. Screening esophagogastroduodenoscopy performed on a 68-year-old woman revealed a yellowish, flat lesion shown to be reddish in its central area, located in the anterior wall of the gastric lower body on white light imaging (WLI). On LCI, the lesion was highlighted as an orangish, flat lesion shown to be purple-colored in its central area, surrounded by lavender-colored tissue. Read More

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http://dx.doi.org/10.1159/000504957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940456PMC
December 2019

An Unconventional Diagnostic Method for Cryptosporidial Enteritis in a Healthy Host: Never Call It Quits!

Case Rep Gastroenterol 2019 Sep-Dec;13(3):526-531. Epub 2019 Dec 12.

Department of Gastroenterology, Staten Island University Hospital, Northwell Health, Staten Island, New York, USA.

Cryptosporidial enteritis has a rising incidence in the USA, mostly affecting immunocompromised individuals and children. It has a self-limiting course in healthy hosts. Herein, we present a unique case of a healthy middle-aged female who presented with a 1-month history of voluminous watery diarrhea and acute blood loss anemia. Read More

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http://dx.doi.org/10.1159/000504956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940464PMC
December 2019

Perforated Jejunal Diverticulitis.

Case Rep Gastroenterol 2019 Sep-Dec;13(3):521-525. Epub 2019 Dec 12.

Internal Medicine, Staten Island University Hospital, Northwell Health, Staten Island, New York, USA.

Small intestinal diverticula are very rare; their incidence ranges from 0.06 to 1.3%, with a higher prevalence after the 6th decade of life. Read More

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http://dx.doi.org/10.1159/000503896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940449PMC
December 2019

Retroperitoneal Liposarcoma with Multilocular Cysts.

Case Rep Gastroenterol 2019 Sep-Dec;13(3):514-520. Epub 2019 Dec 10.

Department of General Surgical Science, Gunma University Graduate School of Medicine, Maebashi, Japan.

In this study, we describe a 60-year-old man with a giant retroperitoneal liposarcoma with multilocular cysts. He was admitted to our hospital because of a 5-month history of abdominal distention. Abdominal computed tomography revealed a giant lobulated cystic mass occupying the retroperitoneal space that contained partially solid fat components. Read More

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http://dx.doi.org/10.1159/000504695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940463PMC
December 2019

Massive Gastrointestinal Bleeding from a Jejunal Dieulafoy Lesion: An Extraordinary Presentation.

Case Rep Gastroenterol 2019 Sep-Dec;13(3):508-513. Epub 2019 Dec 6.

Department of Internal Medicine A, Rambam Health Care Campus, Haifa, Israel.

We present an atypical and rare case of a previously healthy 27-year-old male who presented with acute onset of abdominal pain, bloody diarrhea, and syncope. At the Emergency Department, vital signs were stable with no signs of shock. Physical examination revealed diffuse tenderness of the abdomen and cherry red blood was noted upon rectal examination. Read More

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http://dx.doi.org/10.1159/000495207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940470PMC
December 2019

Fatty Liver and Systemic Atherosclerosis in a Young, Lean Patient: Rule Out Lysosomal Acid Lipase Deficiency.

Case Rep Gastroenterol 2019 Sep-Dec;13(3):498-507. Epub 2019 Dec 4.

Federal Research Center for Nutrition and Biotechnology, Moscow, Russian Federation.

Lysosomal acid lipase deficiency (LALD) is a rare genetic disease characterized by the accumulation of cholesteryl esters and triglycerides in many organs, including the liver, spleen, lymph nodes, bone marrow, and vascular endothelium. Patients with LALD can appear asymptomatic until liver failure or premature sudden death from coronary artery disease, stroke, and aneurysm, which lead to the diagnosis. Herein, we present a diagnostic workup in a young 17-year-old female patient who manifested hepatosplenomegaly, elevated liver enzymes, severe dyslipidemia, and systemic atherosclerosis. Read More

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http://dx.doi.org/10.1159/000504646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940451PMC
December 2019

Isolated Right Ventricular Metastasis in a Woman with Advanced Hepatocellular Carcinoma after Palliative Therapy.

Case Rep Gastroenterol 2019 Sep-Dec;13(3):487-497. Epub 2019 Nov 28.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.

Hepatocellular carcinoma (HCC) with cardiac metastasis represents a group of rarity and poor prognosis. Few case reports have described this patient entity, and it remains unclear regarding the optimal treatment and predicted outcome for these patients. In our case, we represented a 67-year-old female patient with presentations of dyspnea and heart murmur, which conducted to the diagnosis of advanced HCC with isolated right ventricular metastasis. Read More

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http://dx.doi.org/10.1159/000504566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940437PMC
November 2019