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    300 results match your criteria Case reports in endocrinology[Journal]

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    A False Positive I-131 Metastatic Survey Caused by Radioactive Iodine Uptake by a Benign Thymic Cyst.
    Case Rep Endocrinol 2017 20;2017:6469015. Epub 2017 Dec 20.
    Division of Endocrinology and Diabetes, The Robert Larner, M.D. College of Medicine at The University of Vermont, Burlington, VT, USA.
    Thyroid carcinoma is the most common endocrine malignancy in the United States with increasing incidence and diagnosis but stable mortality. Differentiated thyroid cancer rarely presents with distant metastases and is associated with a low risk of morbidity and mortality. Despite this, current protocols recommend remnant ablation with radioactive iodine and evaluation for local and distant metastasis in some patients with higher risk disease. Read More

    Localized Subcutaneous Insulin-Derived Amyloidosis Excised after Evaluation Using Ultrasonography in a Patient with Type 2 Diabetes Mellitus.
    Case Rep Endocrinol 2017 18;2017:3985214. Epub 2017 Dec 18.
    Manda Memorial Hospital Diabetes Center, Sapporo, Japan.
    A 62-year-old man with type 2 diabetes mellitus, who had been on insulin therapy for the past 20 years, was found to have subcutaneous mass formation in the abdomen during a workup of worsened glycemic control. Because of suspected amyloid deposition, he was advised to avoid injections to the mass, which led to improvement of glycemic control. However, he strongly requested mass excision and was hospitalized. Read More

    Effects of Mifepristone on Nonalcoholic Fatty Liver Disease in a Patient with a Cortisol-Secreting Adrenal Adenoma.
    Case Rep Endocrinol 2017 19;2017:6161348. Epub 2017 Nov 19.
    Corcept Therapeutics, 149 Commonwealth Drive, Menlo Park, CA 94025, USA.
    Cushing syndrome (CS), a complex, multisystemic condition resulting from prolonged exposure to cortisol, is frequently associated with nonalcoholic fatty liver disease (NAFLD). In patients with adrenal adenoma(s) and NAFLD, it is essential to rule out coexisting endocrine disorders like CS, so that the underlying condition can be properly addressed. We report a case of a 49-year-old woman with a history of hypertension, prediabetes, dyslipidemia, biopsy-confirmed steatohepatitis, and benign adrenal adenoma, who was referred for endocrine work-up for persistent weight gain. Read More

    Adrenal Oncocytic Neoplasm with Paradoxical Loss of Important Mitochondrial Steroidogenic Protein: The 18 kDA Translocator Protein.
    Case Rep Endocrinol 2017 26;2017:6734695. Epub 2017 Nov 26.
    Department of Pathology, Jackson Memorial Hospital/University of Miami Miller School of Medicine, Miami, FL 33136, USA.
    The adrenal glands produce a variety of hormones that play a key role in the regulation of blood pressure, electrolyte homeostasis, metabolism, immune system suppression, and the body's physiologic response to stress. Adrenal neoplasms can be asymptomatic or can overproduce certain hormones that lead to different clinical manifestations. Oncocytic adrenal neoplasms are infrequent tumors that arise from cells in the adrenal cortex and display a characteristic increase in the number of cytoplasmic mitochondria. Read More

    Rare Cause of Recurrent Hypoglycemia: Insulin Autoimmune Syndrome.
    Case Rep Endocrinol 2017 26;2017:6423852. Epub 2017 Nov 26.
    Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
    We report a case of insulin autoimmune syndrome associated with several autoantibodies, presenting with recurrent hypoglycemia, predominantly in the postprandial period, which improved by dietary management and spontaneously resolved within two months. Differentiation from other causes of hyperinsulinemic hypoglycemia, such as insulinoma, is important to avoid unnecessary invasive procedures or surgical interventions. The 75-gram oral glucose tolerance test (OGTT) and mixed meal test showed a typical pattern, which may be useful indirect evidence of insulin autoimmune syndrome. Read More

    Iatrogenic Cushing's Syndrome with Subsequent Adrenal Insufficiency in a Patient with Psoriasis Vulgaris Using Topical Steroids.
    Case Rep Endocrinol 2017 13;2017:8320254. Epub 2017 Nov 13.
    Department of Endocrinology and Metabolic Diseases, Mugla Sitki Kocman University, Faculty of Medicine, 48000 Mugla, Turkey.
    Iatrogenic Cushing's syndrome (ICS) is usually related to prolonged and/or high-dose oral or parenteral steroid use. Psoriasis vulgaris (PV) is chronic inflammatory disease and characterized by periods of attack and remission. Topical steroid (TS) is the first choice of treatment for localized and mild PV. Read More

    Thyrotoxicosis Associated with a Hypopharyngeal Toxic Nodular Thyroid.
    Case Rep Endocrinol 2017 2;2017:5128563. Epub 2017 Nov 2.
    Division of Nuclear Medicine, Department of Diagnostic Radiology, Dalhousie University, Halifax, NS, Canada.
    Ectopic thyroid is a rare developmental anomaly which may be either asymptomatic or present with thyroid dysfunction as well as pressure symptoms. Here we present a novel case of thyrotoxicosis associated with a hypopharyngeal multinodular thyroid in a female. Removal of the ectopic thyroid led to normalization of the thyroid status. Read More

    Celiac Disease in Patients with Cystic Fibrosis-Related Bone Disease.
    Case Rep Endocrinol 2017 2;2017:2652403. Epub 2017 Nov 2.
    Pulmonary Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
    Both cystic fibrosis (CF) and celiac disease can cause low bone mineral density (BMD) and fractures. Celiac disease may occur at a higher frequency in patients with CF than the general population, and symptoms of these conditions may overlap. We report on two patients presenting with CF-related bone disease in the past year who were subsequently found to have concurrent celiac disease. Read More

    Coexistence of GH-Producing Pituitary Macroadenoma and Meningioma in a Patient with Multiple Endocrine Neoplasia Type 1 with Hyperglycemia and Ketosis as First Clinical Sign.
    Case Rep Endocrinol 2017 1;2017:2390797. Epub 2017 Nov 1.
    Service of Endocrinology and Nutrition, University Clinical Hospital of Salamanca, Paseo de San Vicente No. 58, 37007 Salamanca, Spain.
    We present the clinical case of a patient who was admitted with an onset of diabetes mellitus (DM) with associated ketosis and whose clinical, hormonal, and radiological evolution revealed the presence of primary hyperparathyroidism, pancreatic neuroendocrine tumor, and GH-producing pituitary macroadenoma in the context of multiple endocrine neoplasia type 1 (MEN1). DM is relatively common in cases of acromegaly, but it is not generally associated with ketosis. Simultaneously, the patient presented a meningioma, which is associated with pituitary macroadenoma only in extremely rare cases. Read More

    Coexistence of Primary Hyperaldosteronism and Graves' Disease, a Rare Combination of Endocrine Disorders: Is It beyond a Coincidence-A Case Report and Review of the Literature.
    Case Rep Endocrinol 2017 30;2017:4050458. Epub 2017 Oct 30.
    Department of Endocrinology, Colombo South Teaching Hospital, Kalubowila, Sri Lanka.
    Background: Primary hyperaldosteronism is a known cause for secondary hypertension. In addition to its effect on blood pressure, aldosterone exhibits proinflammatory actions and plays a role in immunomodulation/development of autoimmunity. Recent researches also suggest significant thyroid dysfunction among patients with hyperaldosteronism, but exact causal relationship is not established. Read More

    Diabetes Mellitus Secondary to Acute Pancreatitis in a Child with Wolf-Hirschhorn Syndrome.
    Case Rep Endocrinol 2017 24;2017:3892467. Epub 2017 Oct 24.
    Paediatric Endocrinology Department, Mafraq Hospital, P.O. Box 2951, Abu Dhabi, UAE.
    Wolf-Hirschhorn Syndrome (WHS) is a rare genetic disease caused by deletion in the short arm of chromosome 4. It is characterized by typical fascial features and a varying degree of intellectual disabilities and multiple systemic involvement. Epidemiological studies confirmed the association of acute pancreatitis with the development of diabetes. Read More

    A Novel Mutation of thein a Saudi Infant with Primary Hypoaldosteronism.
    Case Rep Endocrinol 2017 23;2017:8431475. Epub 2017 Oct 23.
    Department of Pediatrics, Prince Sultan Military Medical City, Riyadh 11159, Saudi Arabia.
    Isolated hypoaldosteronism is a rare autosomal recessive disease presenting with severe salt wasting and failure to thrive in infancy. A 6-month-old Saudi girl born to consanguineous parents was referred from primary health care for failure to thrive and developmental delay. Laboratory tests revealed hyponatremia, hyperkalemia, and metabolic acidosis with high renin and low aldosterone. Read More

    Short Stature Homeobox-Containing Haploinsufficiency in Seven Siblings with Short Stature.
    Case Rep Endocrinol 2017 30;2017:7287351. Epub 2017 Aug 30.
    Division of Pediatric Endocrinology, Department of Pediatrics, Nemours Children's Health System, Jacksonville, FL, USA.
    Deficiency of the short stature homeobox-containing (SHOX) gene is a frequent cause of short stature in children (2-15%). Here, we report 7 siblings with SHOX deficiency due to a point mutation in the SHOX gene. Index case was a 3-year-old male who presented for evaluation of short stature. Read More

    Severe Thyrotoxicosis Secondary to Povidone-Iodine from Peritoneal Dialysis.
    Case Rep Endocrinol 2017 24;2017:2683120. Epub 2017 Aug 24.
    Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
    A 73-year-old male on home peritoneal dialysis (PD) with recent diagnosis of atrial fibrillation presented with fatigue and dyspnea. Hyperthyroidism was diagnosed with TSH < 0.01 mIU/L and FT4 > 100 pmol/L. Read More

    A Case of Hyperparathyroidism due to a Large Intrathyroid Parathyroid Adenoma with Recurrent Episodes of Acute Pancreatitis.
    Case Rep Endocrinol 2017 26;2017:5376741. Epub 2017 Jul 26.
    Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori 036-8562, Japan.
    We report a case of a 66-year-old woman who developed hyperparathyroidism due to a large intrathyroid parathyroid adenoma with episodes of acute pancreatitis. She had previously been treated for acute pancreatitis twice. Serum calcium was 12. Read More

    A Recurrent Episode of Dermatomyositis Associated with Papillary Thyroid Cancer.
    Case Rep Endocrinol 2017 19;2017:7985953. Epub 2017 Jul 19.
    Department of Endocrinology, Swedish American Hospital, 1253 N. Alpine Road, Rockford, IL 61107, USA.
    Objective: It is uncommon for dermatomyositis to be associated with papillary thyroid cancer. We report an unusual case of papillary thyroid cancer presenting with dermatomyositis.

    Methods: The case history, imaging and laboratory data is reviewed. Read More

    A Case of Male Osteoporosis: A 37-Year-Old Man with Multiple Vertebral Compression Fractures.
    Case Rep Endocrinol 2017 16;2017:6328524. Epub 2017 Jul 16.
    Division of Endocrinology, Department of Medicine, Jewish General Hospital, McGill University, Montreal, QC, Canada H3T 1E2.
    While the contributing role of testosterone to bone health is rather modest compared to other factors such as estradiol levels, male hypogonadism is associated with low bone mass and fragility fractures. Along with stimulating physical puberty by achieving virilization and a normal muscle mass and improving psychosocial wellbeing, the goals of testosterone replacement therapy in male hypogonadism also include attainment of age-specific bone mineral density. We report on a 37-year-old man who presented with multiple vertebral compression fractures several years following termination of testosterone replacement therapy for presumed constitutional delay in growth and puberty. Read More

    Adrenal Ganglioneuroblastoma in Adults: A Case Report and Review of the Literature.
    Case Rep Endocrinol 2017 21;2017:5796236. Epub 2017 Jun 21.
    Endocrinology Service, Department of Biomedical Sciences for Health, University of Milan, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
    Incidentally discovered adrenal masses are very common given the increased number of imaging studies performed in recent years. We here report a clinical case of a 20-year-old woman who presented with left flank pain. Ultrasound examination revealed a contralateral adrenal mass, which was confirmed at computed tomography (CT) scan. Read More

    Treatment of Nonclassic 11-Hydroxylase Deficiency with Ashwagandha Root.
    Case Rep Endocrinol 2017 20;2017:1869560. Epub 2017 Jun 20.
    Department of Medicine, New York City Health + Hospitals/Woodhull, 760 Broadway, Brooklyn, NY 11206, USA.
    An elderly woman presented with acne and male pattern alopecia, which upon diagnostic evaluation was found to be due to nonclassic 11-hydroxylase deficiency. We previously reported that Ashwagandha root ameliorates nonclassic 3--ol dehydrogenase and aldosterone synthase deficiencies. This is the first report of its use being associated with amelioration of nonclassic 11-hydroxylase deficiency, where its apparent effects appear to be dose-related. Read More

    Papillary Thyroid Carcinoma: Ectopic Malignancy versus Metastatic Disease.
    Case Rep Endocrinol 2017 18;2017:9707031. Epub 2017 Jun 18.
    Endocrinology, SJCH, San Juan, PR, USA.
    Papillary thyroid carcinoma frequently metastasizes to regional lymph nodes. However, cervical lymph node metastasis as a sole manifestation of occult papillary thyroid carcinoma is rarely observed. Ectopic thyroid is an uncommon condition defined as the presence of thyroid tissue at a site other than pretracheal area. Read More

    Effect of Intranasal Calcitonin in a Patient with McCune-Albright Syndrome, Fibrous Dysplasia, and Refractory Bone Pain.
    Case Rep Endocrinol 2017 6;2017:7898713. Epub 2017 Jun 6.
    Gynecological Endocrinology Unit, Division of Endocrinology, Hospital de Clinicas de Porto Alegre, Rua Ramiro Barcelos 2350, 90035-003 Porto Alegre, RS, Brazil.
    McCune-Albright syndrome (MAS) is a rare disease defined by the triad of polyostotic fibrous dysplasia of bone, café-au-lait skin spots, and precocious puberty. No available treatment is effective in changing the course of fibrous dysplasia of bone, but symptomatic patients require therapeutic support to reduce bone pain and prevent fractures and deformities. We report the case of a 27-year-old woman with MAS and severe fibrous dysplasia. Read More

    A Case of "Late" Postsurgical Hypoparathyroidism.
    Case Rep Endocrinol 2017 31;2017:3962951. Epub 2017 May 31.
    Department of Head and Neck Surgery, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, SP, Brazil.
    Introduction: Postsurgical hypoparathyroidism normally occurs a short time after thyroid surgery in form of two clinical syndromes of different etiology and prognosis. The first is transitory and might spontaneously recover within a few weeks or months. The second is permanent and needs a definitive treatment. Read More

    Severe Short Stature in an Adolescent Male with Prader-Willi Syndrome and Congenital Adrenal Hyperplasia: A Therapeutic Conundrum.
    Case Rep Endocrinol 2017 30;2017:4271978. Epub 2017 May 30.
    Division of Pediatric Endocrinology, Rhode Island Hospital and Hasbro Children's Hospital, The Warren Alpert Medical School, Brown University, Providence, RI, USA.
    Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency results in excess androgen production which can lead to early epiphyseal fusion and short stature. Prader-Willi syndrome (PWS) is a genetic disorder resulting from a defect on chromosome 15 due to paternal deletion, maternal uniparental disomy, or imprinting defect. Ninety percent of patients with PWS have short stature. Read More

    Clinical Phenotype in a Toddler with a Novel Heterozygous Mutation of the Vitamin D Receptor.
    Case Rep Endocrinol 2017 23;2017:3905905. Epub 2017 May 23.
    Department of Pediatrics, Division of Pediatric Endocrinology and Diabetes, New York University School of Medicine, New York, NY, USA.
    We present the clinical phenotype of a toddler who presented with vitamin D-resistant rickets, with one of the highest initial levels of alkaline phosphatase and parathyroid hormone (PTH) levels reported in the literature. The toddler had novel compound heterozygous mutations in the ligand-binding site of the vitamin D receptor and had an excellent response to calcitriol (1,25(OH)2D). Read More

    Locally Advanced Thyroglossal Duct Cyst Carcinoma Presenting as a Neck Mass.
    Case Rep Endocrinol 2017 9;2017:7014313. Epub 2017 May 9.
    Department of Endocrinology, Reading Health System, West Reading, PA 19611, USA.
    Thyroglossal duct cyst carcinoma is rare and occurs in just 1% of cases with thyroglossal duct cysts. It is not always possible to distinguish a thyroglossal cyst harboring malignancy from its benign counterparts unless biopsied, thus posing the dilemma. Currently there is no clear consensus on the optimal management of thyroglossal duct cyst carcinoma. Read More

    Humoral Hypercalcemia of Malignancy with a Parathyroid Hormone-Related Peptide-Secreting Intrahepatic Cholangiocarcinoma Accompanied by a Gastric Cancer.
    Case Rep Endocrinol 2017 10;2017:7012520. Epub 2017 May 10.
    Department of Endocrinology and Metabolism, Nagoya City West Medical Center, 1-1-1 Hirate-cho, Kita-ku, Nagoya 462-8508, Japan.
    Humoral hypercalcemia of malignancy (HHM) is caused by the oversecretion of parathyroid hormone-related peptide (PTHrP) from malignant tumors. Although any tumor may cause HHM, that induced by intrahepatic cholangiocarcinoma (ICC) or gastric cancer (GC) is rare. We report here a 74-year-old male who displayed HHM with both ICC and GC and showed an elevated serum PTHrP level. Read More

    Myxedema Crisis Presenting with Seizures: A Rare Life-Threatening Presentation-A Case Report and Review of the Literature.
    Case Rep Endocrinol 2017 2;2017:4285457. Epub 2017 May 2.
    Endocrinology, Colombo South Teaching Hospital, Kalubowila, Sri Lanka.
    Myxedema crisis is a life-threatening extreme form of hypothyroidism with a high mortality rate if left untreated. Myxedema crisis is commonly seen in older patients, especially in women, and is associated with signs of hypothyroidism, hypothermia, hyponatraemia, hypercarbia, and hypoxemia. Patients might present with different organ specific symptoms. Read More

    Hypocalciuric Hypercalcemia due to Impaired Renal Tubular Calcium Excretion in a Type 2 Diabetic Patient.
    Case Rep Endocrinol 2017 11;2017:3694868. Epub 2017 Apr 11.
    Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
    The case we presented here was a 73-year-old gentleman, who was admitted to endocrinology department due to recurrent fatigue for 1 year. He had medical histories of type 2 diabetes for 18 years and developed CKD 4 years ago. He also suffered from dilated cardiomyopathy, and coronary heart disease, moderate sleep apnea syndrome, primary hypothyroidism, and gout. Read More

    Anaplastic Spindle Cell Squamous Carcinoma Arising from Tall Cell Variant Papillary Carcinoma of the Thyroid Gland: A Case Report and Review of the Literature.
    Case Rep Endocrinol 2017 6;2017:4581626. Epub 2017 Apr 6.
    Department of Surgery, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK.
    Tall cell variant (TCV) of papillary thyroid carcinoma (PTC), an aggressive form of thyroid cancer, is characterised by 50% of cells with height that is three times greater than the width. Very rarely, some of these cancers can progress to spindle cell squamous carcinoma (SCSC) resulting in cancers with elements of both SCSC and TCV PTC. Here we report a case of SCSC arising from TCV PTC. Read More

    A Normotensive Patient with Primary Aldosteronism.
    Case Rep Endocrinol 2017 2;2017:5159382. Epub 2017 Apr 2.
    Department of VIP, Fujian Provincial Hospital, Fujian Medical University, 134 East Street, Fuzhou 350001, China.
    This study was to report a case of normotensive patient with primary aldosteronism who was admitted to our department recently. The patient was a 33-year-old male with right adrenal incidentaloma, but without any symptom. He has no history of hypertension, and blood pressure was normal when measured at multiple time points during hospitalization stay. Read More

    A Rare Complication following Thyroid Percutaneous Ethanol Injection: Plummer Adenoma.
    Case Rep Endocrinol 2017 29;2017:1026139. Epub 2017 Mar 29.
    Department of Endocrinology, University Campus Bio-Medico, Rome, Italy.
    Percutaneous ethanol injection (PEI) is a technique used only for benign thyroid nodules, cystic or mixed cystic-solid with a large fluid component. It is a quite low-cost, safe, and outpatient method of treatment. Rare and severe complications have been described after PEI: jugular vein thrombosis and severe ethanol toxic necrosis of the larynx combined with necrotic dermatitis. Read More

    Normalization of Bilateral Adrenal Gland Enlargement after Treatment for Cryptococcosis.
    Case Rep Endocrinol 2017 26;2017:1543149. Epub 2017 Mar 26.
    Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
    Cryptococcosis usually occurs in immunocompromised patients and can cause enlargement of the adrenal glands, although the morphologic changes after treatment have not been reported in detail. We report the case of 24-year-old man with fevers, headaches, and impaired consciousness who had been treated with glucocorticoids for a protein-losing gastroenteropathy. The cerebrospinal fluid analysis revealed cryptococcal meningitis. Read More

    Usefulness of Stereotactic Radiotherapy Using CyberKnife for Recurrent Lymph Node Metastasis of Differentiated Thyroid Cancer.
    Case Rep Endocrinol 2017 15;2017:7956726. Epub 2017 Mar 15.
    Department of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, Japan.
    A woman in her 60s presented with a recurrent lymph node metastasis from a papillary thyroid carcinoma in the right parapharyngeal space. She had already undergone total thyroidectomy, five resections for cervical lymph node metastases, and right carotid rebuilding. Surgical resection of the current metastasis was impossible. Read More

    Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges.
    Case Rep Endocrinol 2017 12;2017:8313162. Epub 2017 Mar 12.
    Unit of Pediatric Endocrinology, 4th Department of Pediatrics, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.
    Androgen Insensitivity Syndrome (AIS) and its heterogeneous phenotypes comprise the pieces of a challenging clinical problem. The lack of standardized guidelines results in controversies regarding the proper diagnostic and therapeutic approach, including the time and type of intervention. Due to its variable phenotype, AIS is not diagnosed at the proper age that would allow optimal psychological and medical support to the patient. Read More

    A Rapid Biochemical and Radiological Response to the Concomitant Therapy with Temozolomide and Radiotherapy in an Aggressive ACTH Pituitary Adenoma.
    Case Rep Endocrinol 2017 5;2017:2419590. Epub 2017 Mar 5.
    Zagreb University School of Medicine, Department of Endocrinology, University Hospital Center Zagreb, Kispaticeva 12, 10000 Zagreb, Croatia.
    . In the last eight years temozolomide (TMZ) has been used as the last-line treatment modality for aggressive pituitary tumors to be applied after the failure of surgery, medical therapy, and radiotherapy. The objective was to achieve a rapid control of tumor growth and hormone normalization with concurrent chemoradiotherapy in a patient with very aggressive ACTH pituitary adenoma. Read More

    Atypical Complications of Graves' Disease: A Case Report and Literature Review.
    Case Rep Endocrinol 2017 28;2017:6087135. Epub 2017 Feb 28.
    Endocrine Department, Hamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
    Graves' disease (GD) may display uncommon manifestations. We report a patient with rare complications of GD and present a comprehensive literature review. A 35-year-old woman presented with a two-week history of dyspnea, palpitations, and edema. Read More

    Addison's Disease and Possible Cannabis Withdrawal Syndrome Presenting as an Eating Disorder in a Thirty-Year-Old Female.
    Case Rep Endocrinol 2017 1;2017:4096021. Epub 2017 Mar 1.
    Department of Family and Community Medicine, North York General Hospital, University of Toronto, Toronto, ON, Canada.
    A 30-year-old female with a history of anxiety, cannabis use, and Avoidant/Restrictive Food Intake Disorder presented for residential treatment of a Cannabis Use Disorder. Upon arrival, she had not eaten for two days and was found to be hypotensive with electrolyte disturbances. She was admitted to a nearby hospital, where the Internist diagnosed her with Addison's disease. Read More

    Pituitary Adenoma and Hyperprolactinemia Accompanied by Idiopathic Granulomatous Mastitis.
    Case Rep Endocrinol 2017 22;2017:3974291. Epub 2017 Feb 22.
    General Surgery Department, Liv Hospital, Ulus, Istanbul, Turkey.
    Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory disease of the breast, and its etiology remains not fully elucidated. IGM is observed more often in patients with autoimmune disease. Hyperprolactinemia is observed during pregnancy, lactation, and a history of oral contraceptive use. Read More

    Simultaneous Papillary Carcinoma in Thyroglossal Duct Cyst and Thyroid.
    Case Rep Endocrinol 2017 8;2017:8541078. Epub 2017 Feb 8.
    Division of Endocrinology, Hospital Mario Pena, Belo Horizonte, MG, Brazil.
    Thyroglossal duct cyst (TDC) is a cystic expansion of a remnant of the thyroglossal duct tract. Carcinomas in the TDC are extremely rare and are usually an incidental finding after the Sistrunk procedure. In this report, an unusual case of a 36-year-old woman with concurrent papillary thyroid carcinoma arising in the TDC and on the thyroid gland is presented, followed by a discussion of the controversies surrounding the possible origins of a papillary carcinoma in the TDC, as well as the current management options. Read More

    False Positive Findings on I-131 WBS and SPECT/CT in Patients with History of Thyroid Cancer: Case Series.
    Case Rep Endocrinol 2017 26;2017:8568347. Epub 2017 Jan 26.
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
    Although whole body scan (WBS) with I-131 is a highly sensitive tool for detecting normal thyroid tissue and metastasis of differentiated thyroid cancer (DTC), it is not specific. Additional information, provided by single photon emission computed tomography combined with X-ray computed tomography (SPECT/CT) and by the serum thyroglobulin level, is extremely useful for the interpretation of findings.We report four cases of false positive WBS in patients with DTC: ovarian uptake corresponding to an endometrioma, scrotal uptake due to a spermatocele, rib-cage uptake due to an old fracture, and hepatic and renal uptake secondary to a granuloma and simple cyst, respectively. Read More

    Hypercalcemia of Malignancy in Thymic Carcinoma: Evolving Mechanisms of Hypercalcemia and Targeted Therapies.
    Case Rep Endocrinol 2017 12;2017:2608392. Epub 2017 Jan 12.
    Division of Endocrinology and Metabolism, Rush University Medical Center, Chicago, IL, USA.
    Here we describe, to our knowledge, the first case where an evolution of mechanisms responsible for hypercalcemia occurred in undifferentiated thymic carcinoma and discuss specific management strategies for hypercalcemia of malignancy (HCM).. We report a 26-year-old male with newly diagnosed undifferentiated thymic carcinoma associated with HCM. Read More

    Asymptomatic Congenital Hyperinsulinism due to a Glucokinase-Activating Mutation, Treated as Adrenal Insufficiency for Twelve Years.
    Case Rep Endocrinol 2017 9;2017:4709262. Epub 2017 Jan 9.
    Center for Diabetes, Endocrinology and Metabolism, Shizuoka General Hospital, No. 4-27-1, Kita-Ando, Aoi-ku, Shizuoka, Shizuoka 420-8527, Japan.
    Congenital hyperinsulinism (CHI) caused by a glucokinase- (GCK-) activating mutation shows autosomal dominant inheritance, and its severity ranges from mild to severe. A 43-year-old female with asymptomatic hypoglycemia (47 mg/dL) was diagnosed as partial adrenal insufficiency and the administration of hydrocortisone (10 mg/day) was initiated. Twelve years later, her 8-month-old grandchild was diagnosed with CHI. Read More

    Isolated Liver Metastasis in Hürthle Cell Thyroid Cancer Treated with Microwave Ablation.
    Case Rep Endocrinol 2017 9;2017:2790741. Epub 2017 Jan 9.
    Endocrinology, Diabetes and Metabolism, The Ohio State University Wexner Medical Center, 5th Floor McCampbell Hall, 1581 Dodd Drive, Columbus, OH 43210, USA.
    Hürthle cell thyroid cancer (HCTC) is a less common form of differentiated thyroid cancer. It rarely metastasizes to the liver, and when it does, the metastasis is almost never isolated. Here we report a 62-year-old male with widely invasive Hürthle cell thyroid cancer, who underwent total thyroidectomy and received adjuvant treatment with I-131 with posttreatment scan showing no evidence of metastatic disease. Read More

    Horner Syndrome Secondary to Thyroid Surgery.
    Case Rep Endocrinol 2017 4;2017:1689039. Epub 2017 Jan 4.
    Department of Pediatric Surgery, School of Medicine, Eskişehir Osmangazi University, Eskişehir, Turkey.
    Horner syndrome (HS), caused by an interruption in the oculosympathetic pathway, is characterised by myosis, ipsilateral blepharoptosis, enophthalmos, facial anhydrosis, and vascular dilation of the lateral part of the face. HS is a rare complication of thyroidectomy. A 15-year-old female patient presented with solitary solid and large nodule in the right thyroid lobe. Read More

    Vasopressin Bolus Protocol Compared to Desmopressin (DDAVP) for Managing Acute, Postoperative Central Diabetes Insipidus and Hypovolemic Shock.
    Case Rep Endocrinol 2017 3;2017:3052102. Epub 2017 Jan 3.
    Department of Neurology, University of Missouri, Columbia, MO, USA.
    . Management of postoperative central diabetes insipidus (DI) can be challenging from changes in volume status and serum sodium levels. We report a case successfully using a dilute vasopressin bolus protocol in managing hypovolemic shock in acute, postoperative, central DI. Read More

    Artifactual Hypoglycaemia in Systemic Sclerosis and Raynaud's Phenomenon: A Clinical Case Report and Short Review.
    Case Rep Endocrinol 2016 28;2016:7390927. Epub 2016 Dec 28.
    Department of Endocrinology and Metabolism, Concord Repatriation General Hospital, Concord, Sydney, NSW 2139, Australia; Sydney Medical School, University of Sydney, Sydney, NSW 2005, Australia.
    . Artifactual hypoglycaemia, defined as a discrepancy between glucometer (capillary) and plasma glucose levels, may lead to overtreatment and costly investigations. It is not infrequently observed in patients with Raynaud's phenomenon due to vascular capillary distortion, yet this is clinically underappreciated. Read More

    Nodular Lymphocyte Predominant Hodgkin Lymphoma of the Thyroid.
    Case Rep Endocrinol 2016 1;2016:8756723. Epub 2016 Dec 1.
    Endocrinology Department, Hospital de Egas Moniz, Lisboa, Portugal.
    Thyroid lymphomas are rare clinical entities that may result from either the primary intrathyroidor secondary thyroid gland involvement of a lymphoma. Among these, the Hodgkin's subtype is quite uncommon, accounting for 0.6-5% of all thyroid malignancies. Read More

    Unusual Cushing's Syndrome and Hypercalcitoninaemia due to a Small Cell Prostate Carcinoma.
    Case Rep Endocrinol 2016 1;2016:6308058. Epub 2016 Dec 1.
    Pathology Unit, "M. Bufalini" Hospital, ASL of Romagna, Cesena, Italy.
    A 75-year-old man was hospitalized because of severe hypokalaemia due to ACTH dependent Cushing's syndrome. Total body computed tomography (TBCT) and 68 Gallium DOTATATE PET/CT localized a voluminous prostate tumour. A subsequent transurethral prostate biopsy documented a small cell carcinoma positive for ACTH and calcitonin and negative for prostatic specific antigen (PSA) at immunocytochemical study; serum prostatic specific antigen (PSA) was normal. Read More

    A 33-Year-Old Man with Gynaecomastia and Galactorrhea as the First Symptoms of Graves Hyperthyroidism.
    Case Rep Endocrinol 2016 1;2016:1946824. Epub 2016 Dec 1.
    Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
    Graves' hyperthyroidism has a various number of well-recognized manifestations. Galactorrhea is a rare manifestation in this disease. We describe a 33-year-old man who presented with the symptoms of hyperthyroidism, gynaecomastia, and galactorrhea for 2 months. Read More

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