3,228,505 results match your criteria Case reports in endocrinology[Journal]


[The Rezūm system in the treatment of male lower urinary tract symptoms (LUTSs) due to benign prostatic obstruction (BPO)].

Aktuelle Urol 2018 Dec 6;49(6):519-524. Epub 2018 Dec 6.

Spital Thurgau AG, Urologie, Frauenfeld.

The classical algorithm of the management of male lower urinary tract symptoms (LUTSs) due to benign prostatic hyperplasia (BPH) includes a surgical approach in case pharmacological therapy has failed. Emerging minimally-invasive treatments (MITs) offer potential for rapid symptomatic relief, reducing the morbidity of invasive BPH surgery. Convective interstitial radiofrequency water vapour thermal ablation of the prostate with the Rezūm system is a novel MIT for the treatment of bothersome moderate-to-severe lower urinary tract symptoms associated with BPH. Read More

View Article
December 2018
8 Reads

Hypercortisolism in Newly Diagnosed Type 2 Diabetes: A Prospective Study of 384 Newly Diagnosed Patients.

Horm Metab Res 2018 Dec 6. Epub 2018 Dec 6.

Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.

Cross-sectional studies in small and selected populations report a high prevalence of hypercortisolism in patients with type 2 diabetes (T2D), which could have therapeutic implications, if confirmed. We therefore estimated the prevalence of hypercortisolism in a large and unselected cohort of recently diagnosed T2D patients. Consecutive patients with recently diagnosed T2D first underwent an overnight dexamethasone (1 mg) suppression test (OD). Read More

View Article
December 2018
1 Read

Effect of Sodium Glucose Co-Transporter-2 Inhibition on the Aldosterone/Renin Ratio in Type 2 Diabetes Mellitus.

Horm Metab Res 2018 Dec 6. Epub 2018 Dec 6.

Department of Clinical Biochemistry, Saolta University Health Care Group (SUHCG), Galway University Hospitals, Galway, Ireland.

The aldosterone to renin ratio (ARR) is recommended for case detection of primary aldosteronism (PA). Several factors including medications can undermine its diagnostic accuracy. The objective was to explore the effect of Sodium Glucose Co-Transporter-2 Inhibition on the ARR in patients with type 2 diabetes mellitus (T2DM) who were prescribed a Sodium Glucose Co-Transporter-2 Inhibitor (SGLT-2i) as part of routine clinical care. Read More

View Article
December 2018
1 Read

Submuscular gluteal abcess: An unusual presentation of rare sacral tuberculosis.

Int J Surg Case Rep 2018 Nov 24;54:55-59. Epub 2018 Nov 24.

Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital - Faculty of Medicine Universitas, Jl. Pangeran Diponegoro No. 71, Salemba, Central Jakarta, 10430, Indonesia. Electronic address:

Introduction: Both gluteal abscess and sacral tuberculosis are rare entities in spinal tuberculosis cases. Even in endemic country, this atypical presentation may be the cause of delayed diagnosis and treatment.

Presentation Of Case: A 51-year-old woman was admitted with painless massive lump on both of her thighs that have been enlarging for the past 6 months. Read More

View Article
November 2018
2 Reads

Clostridium septicum: A usual suspect? Aortic rupture following right hemicolectomy: A case report.

Int J Surg Case Rep 2018 Nov 22;54:51-54. Epub 2018 Nov 22.

Department of Surgery, Epworth Health, Melbourne Australia; Gastrointestinal Clinical Institute, Epworth HealthCare, Melbourne Australia.

Introduction: There is a known association between Clostridium Septicum, mycotic aneurysm and colon neoplasm.

Case Presentation: We report the case of a 90 year old female admitted with abdominal pain to the general surgery unit. Admission CT scan demonstrated a thick walled caecum and pericaecal inflammation suspicious for a perforated carcinoma. Read More

View Article
November 2018
1 Read

A giant sacrococcygeal teratoma in adult female: A case report.

Int J Surg Case Rep 2018 Nov 22;54:47-50. Epub 2018 Nov 22.

Department of General Surgery, King Abdulla University Hospital, Faculty of Medicine, Jordan University of Science and Technology, P.O. Box (3030), Irbid, 22110, Jordan. Electronic address:

Introduction: Sacrococcygealteratoma is very rare in adults with only few cases reported in literature. It is a slow growing benign cystic tumor with 1-2% chance for malignant transformation and may attain a huge size causing pressure effect on pelvic and intra-abdominal organs. When grows caudally, it causes discomfort, skin excoriation and cosmetic disfigurement. Read More

View Article
November 2018
4 Reads

Case report: Disseminated pulmonary mucormycosis involving spleen in diabetic patient with aggressive surgical approach.

Int J Surg Case Rep 2018 Nov 29;54:42-46. Epub 2018 Nov 29.

Department of General Surgery, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.

Introduction: Mucormycosis is a life threatening fungal infection that occurs in immunocompromised patients.

Presentation Of Case: A 36-year-old Saudi male with known case of Insulin-Dependent Diabetes Mellitus (IDDM), who was presented with productive cough and diarrhea. Computed tomography (CT) revealed a disseminated fungal invasion of the lungs and spleen with invading the fundus of the stomach. Read More

View Article
November 2018

The adoption of sustainable practices: A supplier's perspective.

J Environ Manage 2018 Dec 3;232:692-701. Epub 2018 Dec 3.

Chinese Academy of Environmental Planning, Beijing, China.

Suppliers' adoption of sustainable practices plays a critical role for global companies to improve environmental performance. Based on the absorptive capacity theory, this study empirically explores how suppliers' knowledge bases and power relationships influence their adoption of sustainability practices. A longitudinal case study with eight suppliers has been conducted. Read More

View Article
December 2018
4 Reads

How much of a market is involved in a biodiversity offset? A typology of biodiversity offset policies.

J Environ Manage 2018 Dec 3;232:679-691. Epub 2018 Dec 3.

Stockholm Resilience Centre, Stockholm University, Kräftriket 2B, SE-114 19, Stockholm, Sweden.

Biodiversity offsets (BO) are increasingly promoted and adopted by governments and companies worldwide as a policy instrument to compensate for biodiversity losses from infrastructure development projects. BO are often classified as 'market-based instruments' both by proponents and critics, but this representation fails to capture the varieties of how BO policies actually operate. To provide a framing for understanding the empirical diversity of BO policy designs, we present an ideal-typical typology based on the institutions from which BO is organised: Public Agency, Mandatory Market and Voluntary Offset. Read More

View Article
December 2018

Occurrence and levels of micropollutants across environmental and engineered compartments in Austria.

J Environ Manage 2018 Dec 3;232:636-653. Epub 2018 Dec 3.

Institute for Water Quality and Resource Management, TU Wien, Karlsplatz 13/226, 1040, Vienna, Austria.

Occurrence and concentration of a broad spectrum of micropollutants are investigated in Austrian river catchments, namely polycyclic aromatic hydrocarbons (PAHs), polybrominated diphenyl ethers (PBDEs), organotin compounds, perfluoroalkyl acids (PFAAs) and metals. The parallel analysis across multiple environmental and engineered compartments sheds light on the ratio of dissolved and particulate transport and on differences in concentration levels between point and diffuse emission pathways. It is found that some PAHs and organotins are present in rivers, groundwater and bulk deposition at higher concentrations than in municipal wastewater effluents. Read More

View Article
December 2018
1 Read

A systematic review of sudden unexpected death in epilepsy (SUDEP) in childhood.

Epilepsy Behav 2018 Dec 3;90:99-106. Epub 2018 Dec 3.

Population, Policy and Practice Unit, UCL Great Ormond Street Institute of Child Health, London, United Kingdom.

Background: Sudden Unexpected Death in Epilepsy (SUDEP) is a significant cause of death in childhood epilepsy, and causes considerable concern to patients and their families. Despite this, the condition remains poorly understood. This systematic review investigates the risk factors, pathophysiology, and circumstances associated with childhood SUDEP. Read More

View Article
December 2018
12 Reads

Corticosteroid-dependent tuberculous meningitis: A case report.

J Neurol Sci 2018 Nov 17;396:232-234. Epub 2018 Nov 17.

Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan. Electronic address:

View Article
November 2018
1 Read

An environmental flow determination method for integrating multiple-scale ecohydrological and complex ecosystem processes in estuaries.

Sci Total Environ 2018 Nov 22;656:482-494. Epub 2018 Nov 22.

Nelson Mandela University, PO Box 77000, Port Elizabeth 6031, South Africa. Electronic address:

This paper presents an environmental flow methodology that was developed to accommodate shallow, highly dynamic micro-tidal estuaries found along the wave-dominated coast of South Arica. This method differs to most other approaches that primarily focus on larger permanently open systems having unrestricted inlets. Following an adaptive, design science research approach, the 7-step method adopted both ecohydrological and ecosystem-based concepts, encapsulating key hydrologicalhydrodynamic-biogeochemical processes, as well as biotic responses. Read More

View Article
November 2018
2 Reads

Evaluation of hetero-multivalent lectin binding using a turbidity-based emulsion agglutination assay.

Colloids Surf B Biointerfaces 2018 Nov 28;175:84-90. Epub 2018 Nov 28.

Dept. of Chemical Engineering, Texas A&M University, College Station, TX, 77843, USA. Electronic address:

Lectin hetero-multivalency, binding to two or more different types of ligands, has been demonstrated to play a role in case of both LecA (a Pseudomonas aeruginosa adhesin) and Cholera Toxin subunit B (a Vibrio cholerae toxin). In order to screen the ligand candidates that involve in hetero-multivalent binding from large molecular libraries, we present a turbidity-based emulsion agglutination (TEA) assay that can be conducted in a high-throughput format using the standard laboratory instruments and reagents. The benefit of this assay is that it relies on the use of emulsions that can be formed using ultrasonication, minimizing the bottleneck of substrate surface functionalization. Read More

View Article
November 2018
1 Read

Developing crash prediction models using parametric and nonparametric approaches for rural mountainous freeways: A case study on Wyoming Interstate 80.

Accid Anal Prev 2018 Dec 3;123:176-189. Epub 2018 Dec 3.

Department of Mathematics and Statistics, University of Wyoming, 1000 E University Ave, Laramie, WY 82071, USA. Electronic address:

Interstate 80 in Wyoming is one of the busiest freight corridors that is characterized with harsh winter conditions and challenging mountainous roadway sections. The fatality rates in Wyoming are always typically higher than the national level. The 402-mile I-80 corridor in Wyoming was selected by the USDOT FHWA for piloting connected vehicle technology to improve the safety and mobility of heavy trucks. Read More

View Article
December 2018

Combined juvenile polyposis syndrome and hereditary hemorrhagic telangiectasia (JPS/HHT) with MRI and endoscopic correlation.

Clin Imaging 2018 Dec 2;54:37-39. Epub 2018 Dec 2.

Department of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Ave., Boston, MA 02215, USA.

Juvenile polyposis syndrome (JPS) may coexist with hereditary hemorrhagic telangiectasia (HHT) due to implication of the SMAD4 gene in a subset of both diseases. To the best of our knowledge, we present the first case in the radiologic literature on the MRI findings in a patient with this rare combined diagnosis undergoing workup for burden of disease. Read More

View Article
December 2018
2 Reads

Epithelioid Osteoblastoma of the Temporal Bone: A Case Report.

World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.

Department of Pathology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital.

View Article
December 2018
1 Read

Ultrasonic scalpel-assisted endoscopic endonasal surgery of infratemporal fossa: our first impressions.

World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.

Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, HNS&FDRc, University of Insubria, Varese, Italy.

Background: Endoscopic endonasal transpterygoid approach is emerging as a valid option for treating selected tumors in the infratemporal fossa. Compared to traditional open approaches, the endoscopic endonasal approach (EEA) presents more difficulty in controlling bleeding and less choice in surgical instruments for endoscopic tumor dissection, which is often performed with bipolar forceps or steel dissectors.

Case Description: We describe the use of an ultrasonic scalpel device for performing endoscopic endonasal resection of two rare infratemporal fossa tumors (mature teratoma and hemangiopericytoma), which has not been reported in the literature so far. Read More

View Article
December 2018
1 Read

Spinal arachnoiditis ossificans: report of a quadruple triggered case.

World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.

Department of Neurological Surgery, Policlinico "G. Rodolico" University Hospital, Via Santa Sofia 86, 95123 - Catania, Italy.

Background: Arachnoiditis ossificans (AO) is a rare condition often associated with previous spine surgery. Here we describe a unique case of a patient affected by ankylosing spondylitis (AS), presenting with progressive neurological deterioration due to AO. We also review the literature on evaluation and management of patients suffering from AO. Read More

View Article
December 2018
1 Read

Cytochrome P450 epoxygenases and cancer: A genetic and a molecular perspective.

Pharmacol Ther 2018 Dec 3. Epub 2018 Dec 3.

Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee;; Department of Veterans Affairs, Nashville, TN, USA. Electronic address:

Cytochrome CYP450 epoxygenases catalyze the epoxidation of polyunsaturated fatty acids including arachidonic acid, eicosapentaenoic acid, and docosahexaenoic acid. The arachidonic acid-derived products are potent pro-angiogenic lipids and promote tumor development and growth. On the other hand, eicosapentaenoic acid- and docosahexaenoic acid-derived products inhibit angiogenesis and play a protective role in certain pathological conditions including cancer. Read More

View Article
December 2018
2 Reads

Biased perspectives on formyl peptide receptors.

Biochim Biophys Acta Mol Cell Res 2018 Dec 3. Epub 2018 Dec 3.

Institute of Medical Biochemistry, Center for Molecular Biology of Inflammation, University of Muenster, Von-Esmarch-Str. 56, D-48149 Muenster, Germany; Cluster of Excellence "Cells in Motion", University of Muenster, D-48149 Muenster, Germany. Electronic address:

The innate immune system is the first line of defense against pathogenic threats. For the early pathogen recognition and activation of cell protective mechanisms, germline-encoded pattern recognition receptors (PRRs) detect characteristic and evolutionary conserved pathogen-associated molecular patterns (PAMPs). PRRs are therefore key elements in the innate immune response; in addition, they sense danger-associated molecular patterns (DAMPs) that are released by host cell molecules under pathophysiological conditions. Read More

View Article
December 2018
2 Reads

Fluorescence polarization assay: Diagnostic evaluation for porcine brucellosis.

J Microbiol Methods 2018 Dec 3. Epub 2018 Dec 3.

Indian Council Agricultural Research-National Institute of Veterinary Epidemiology and Disease Informatics, Yelahanka, Bengaluru 560064, India. Electronic address:

Brucellosis in pigs, caused by the bacterium Brucella suis, is an important zoonotic infection. In the present study, fluorescence polarization assay (FPA) was standardized and compared with indirect enzyme linked immunosorbent assay (iELISA) and competitive ELISA (cELISA) for diagnosis of porcine brucellosis. Test performances were evaluated using representative panel (n = 100), samples from swine brucellosis outbreak (n = 300), samples from brucellosis suspected animals (n = 291) and sera samples from apparently healthy animals (n = 1121). Read More

View Article
December 2018
3 Reads

Bezlotoxumab Use as Adjunctive Therapy with the Third Fecal Microbiota Transplant in Refractory Recurrent Clostridium Difficile Colitis; A Case Report and Concise Literature Review.

Anaerobe 2018 Dec 3. Epub 2018 Dec 3.

ABIM Board Certified in Focused Practice in Hospital Medicine (FPHM), Mercy Clinic Hospitalist, Physician Building, 7301 Rogers Ave, Fort Smith, AR, 72903, United States. Electronic address:

Clostridium difficile is the most commonly reported pathogen to cause nosocomial infections in the United States with a high burden affecting morbidity, mortality and healthcare expenditure. The use of Fecal Microbiota Transplantation (FMT) is one of the current standard therapies for recurrent C. difficile infection (CDIr). Read More

View Article
December 2018
1 Read

Influence of various uropathogens on crystallization of urine mineral components caused by Proteus mirabilis.

Res Microbiol 2018 Dec 3. Epub 2018 Dec 3.

Department of Biology of Bacteria, Faculty of Biology and Environmental Protection, University of Łódź, Banacha 12/16, 90-237 Łódź, Poland. Electronic address:

Infectious urolithiasis is a consequence of long-standing urinary tract infections with urease-positive bacteria, especially Proteus spp. However, because of the often mixed nature of urinary tract infections, in the case of urinary stones formation, several species of bacteria may be involved in the process. The purpose of the study was to determine the impact of the bacterial species: Escherichia coli, Klebsiella pneumoniae, Providencia stuartii, Pseudomonas aeruginosa and Staphylococcus aureus on the crystallization caused by Proteus mirabilis. Read More

View Article
December 2018
1 Read

Hide and Seek.

Surv Ophthalmol 2018 Dec 3. Epub 2018 Dec 3.

Wills Eye Hospital , Thomas Jefferson University, Philadelphia PA.

A 51-year-old woman with a previous history of rheumatoid arthritis experienced painless and progressive visual loss in the left eye for three weeks. Fundus examination revealed optic disc pallor in her left eye. Magnetic resonance imaging of the brain and orbits showed enhancement of the pachymeninges and hypersignal at the left optic nerve. Read More

View Article
December 2018
2 Reads

The X Factor.

Surv Ophthalmol 2018 Dec 3. Epub 2018 Dec 3.

Associate Professor, Departments of Clinical Neurosciences and Surgery, University of Calgary.

A 45-year-old Caucasian woman presented with chronic bilateral, painless, progressive, peripheral vision loss. She was found to have bilateral optic atrophy and non-enhancing multifocal white matter lesions on magnetic resonance imaging of the brain. Cerebrospinal fluid analysis showed elevated myelin basic protein. Read More

View Article
December 2018
3 Reads

Expression of the neuropeptides RFamide and LWamide during development of the coral Acropora millepora in relation to settlement and metamorphosis.

Dev Biol 2018 Dec 3. Epub 2018 Dec 3.

Division of Ecology and Evolution, Bldg 46, Research School of Biology, Australian National University, Canberra, ACT 0200, Australia; ARC Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, QLD 4811, Australia. Electronic address:

Neuropeptides play critical roles in cnidarian development. However, although they are known to play key roles in settlement and metamorphosis, their temporal and spatial developmental expression has not previously been characterized in any coral. We here describe Acropora millepora LWamide and RFamide and their developmental expression from the time of their first appearance, using in situ hybridization and FMRFamide immunohistochemistry. Read More

View Article
December 2018
2 Reads

The potential role of the sphaeractinomyxon collective group (Cnidaria, Myxozoa) in the life cycle of mugiliform-infecting myxobolids, with the morphological and molecular description of three new types from the oligochaete Tubificoides insularis.

J Invertebr Pathol 2018 Dec 3. Epub 2018 Dec 3.

Laboratory of Animal Pathology, Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal; University Institute of Health Sciences & Institute of Research and Advanced Training in Health Sciences and Technologies (CESPU), Rua Central da Gandra no. 1317, 4585-116 Gandra, Portugal.

Three new types of sphaeractinomyxon (Cnidaria, Myxozoa) are described from the coelomic cavity of the marine oligochaete Tubificoides insularis, collected from the Alvor estuary, Algarve, Portugal. Another known type is also registered from this location and host: Sphaeractinomyxon type 10 of Rangel et al., 2016, which was originally described from the marine oligochaete Tubificoides pseudogaster in the Aveiro estuary, Portugal. Read More

View Article
December 2018

Preterm newborn's postnatal growth patterns: how to evaluate them.

J Pediatr (Rio J) 2018 Dec 3. Epub 2018 Dec 3.

Universidade Federal do Rio Grande do Sul (UFRGS), Departamento de Pediatria, Porto Alegre, RS, Brazil; Hospital de Clínicas de Porto Alegre (HCPA), Serviço de Neonatologia, Porto Alegre, RS, Brazil.

Objectives: There are several factors that influence the postnatal growth of preterm infants. It is crucial to define how to evaluate the growth rate of each preterm child and its individual trajectory, the type of growth curve, either with parameters of prescriptive curves for healthy preterm infants with no morbidities or, in the case of preterm infants and their "bundle of vulnerabilities", growth curves that may represent how they are actually growing, with the aim of directing appropriate nutritional care to each gestational age range.

Data Sources: The main studies with growth curves for growth monitoring and the appropriate nutritional adjustments that prioritized the individual trajectory of postnatal growth rate were reviewed. Read More

View Article
December 2018

Solriamfetol for Excessive Sleepiness in Obstructive Sleep Apnea (TONES 3): A Randomized Controlled Trial.

Am J Respir Crit Care Med 2018 Dec 6. Epub 2018 Dec 6.

Case Western Reserve University, Cleveland, Ohio, United States.

Rationale: Primary treatment of obstructive sleep apnea can be accompanied by a persistence of excessive sleepiness despite adherence. Furthermore, effectiveness of sleep apnea treatment is limited by poor adherence. Currently available pharmacologic options for the treatment of sleepiness in this population are limited. Read More

View Article
December 2018

[Dedifferentiated diaphyseal juxtacortical osteosarcoma of ulna with metastasis to the lung].

Acta Ortop Mex 2018 May-Jun;32(3):167-171

Departamento de Piel y Partes Blandas del Instituto Nacional de Cancerología. Ciudad de México, México.

Dedifferentiated parosteal osteosarcoma is a variant in which a high grade osteosarcoma coexists with a parosteal osteosarcoma. We report the case of a 20-year-old female patient who presented with six months of evolution of pain and functional limitation of the right forearm, with no apparent cause; radiographs were performed, observing a tumoral lesion in the diaphysis of the right ulna. Physical examination showed pain upon palpation in the diaphysis of the ulna and limitation of prone-supination. Read More

View Article
December 2018
2 Reads

[Interlocking femoral nail and total knee Arthroplasty in one stage for a patient with a femoral diaphyseal stress fracture].

Acta Ortop Mex 2018 May-Jun;32(3):163-166

Servicio de Cirugía Ortopédica y Traumatología, Hospital de Sabadell. Institut Universitari Parc Taulí Universitat Autònoma de Barcelona, España.

We present the case of an 81-year-old woman who was followed up by the Rheumatology Service for osteoporosis and treated with bisphosphonates for more than five years. She reported a fracture of the distal third of the contralateral femur by a low energy mechanism, treated with retrograde intramedullary nailing the previous year. She presented a clinic of cruralgia and left gonalgia, without previous trauma. Read More

View Article
December 2018

Catalyst-Controlled 1,2- and 1,1-Arylboration of α-Alkyl Alkenylarenes.

Angew Chem Int Ed Engl 2018 Dec 6. Epub 2018 Dec 6.

Indiana University, Department of Chemistry, 800 E. Kirkwood Ave, 47401, Bloomington, UNITED STATES.

Two methods are reported that achieve the 1,2- and 1,1-arylboration of α-alkyl alkenylarenes. In the case of 1,2-arylboration, the formation of quaternary centers was achieved through a rare cross-coupling of a tertiary organometallic complex. 1,1-Arylboration was accomplished through catalyst optimization and occurs through a β-hydride elimination/reinsertion cascade. Read More

View Article
December 2018

Early experience of transoral thyroidectomy: Comparison of robotic and endoscopic procedures.

Head Neck 2018 Dec 6. Epub 2018 Dec 6.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Background: The aim of this study was to evaluate the feasibility, safety, and early surgical outcomes of transoral thyroidectomy and to compare robotic and endoscopic procedures.

Methods: A total of 37 patients underwent robotic (23 cases) or endoscopic (14 cases) transoral thyroidectomy. We compared the outcomes of the two procedures. Read More

View Article
December 2018
3 Reads

Inhaled steroids with and without regular salmeterol for asthma: serious adverse events.

Cochrane Database Syst Rev 2018 Dec 3;12:CD006922. Epub 2018 Dec 3.

Population Health Research Institute, St George's, University of London, Cranmer Terrace, London, UK, SW17 0RE.

Background: Epidemiological evidence has suggested a link between use of beta₂-agonists and increased asthma mortality. Much debate has surrounded possible causal links for this association, and whether regular (daily) long-acting beta₂-agonists (LABAs) are safe, particularly when used in combination with inhaled corticosteroids (ICSs). This is an update of a Cochrane Review that now includes data from two large trials including 11,679 adults and 6208 children; both were mandated by the US Food and Drug Administration (FDA). Read More

View Article
December 2018
5 Reads

Mandible reconstruction with patient-specific implants: Case report of five consecutive patients.

Int J Oral Maxillofac Implants 2018 Dec 5. Epub 2018 Dec 5.

The purpose of this case report was to assess whether patient-specific implants (PSI: Xillocs) and soft tissue flaps contribute in reconstructing large mandibular defects. Five patients with a medical situation and history not suitable for free microvascular bone flaps were operated with PSI and evaluated. The mean follow-up time was 12 months. Read More

View Article
December 2018
1 Read

Association of colorectal polyps and cancer with low-dose persistent organic pollutants: A case-control study.

PLoS One 2018 6;13(12):e0208546. Epub 2018 Dec 6.

Department of Preventive Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.

Background: Low-dose persistent organic pollutants (POPs) have recently been linked to immunosenescence, a key mechanism in carcinogenesis, as well as many aging-related chronic diseases. Since feces are the main excretion route of POPs, the large intestine is a potential target organ for these pollutants. We performed a case-control study to evaluate whether exposure to low-dose POPs is related to the risk of colorectal polyps and cancer. Read More

View Article
December 2018

Comparison of brain magnetic resonance imaging between myotonic dystrophy type 1 and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

PLoS One 2018 6;13(12):e0208620. Epub 2018 Dec 6.

Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Background: Anterior temporal lobe hyperintensities detected by brain MRI are a recognized imaging hallmark of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Because similar findings may be present in patients with myotonic dystrophy type 1 (DM1), the brain MRI in these two diseases is often misinterpreted. We compared the MRI findings between the two entities to examine whether they display distinctive characteristics. Read More

View Article
December 2018
4 Reads

Effect estimate comparison between the prescription sequence symmetry analysis (PSSA) and parallel group study designs: A systematic review.

PLoS One 2018 6;13(12):e0208389. Epub 2018 Dec 6.

Groningen Research Institute of Pharmacy, unit PharmacoTherapy, -Epidemiology & -Economics, University of Groningen, Groningen, The Netherlands.

Prescription sequence symmetry analysis (PSSA), a case-only design introduced in 1996, has been increasingly used to identify unintentional drug effects, and has potential applications as a hypothesis-testing and a hypothesis-generating method, due to its easy application and effective control of time-invariant confounders. The aim of this study is to systematically compare effect estimates from the PSSA to effect estimates from conventional observational parallel group study designs, to assess the validity and constraints of the PSSA study design. We reviewed the MEDLINE, EMBASE, and Web of Science databases until February 2016 to identify studies that compared PSSA to a parallel group design. Read More

View Article
December 2018

Atypical and severe manifestations of chikungunya virus infection in French Guiana: A hospital-based study.

PLoS One 2018 6;13(12):e0207406. Epub 2018 Dec 6.

Tropical and Infectious Diseases Department, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana.

Background: French Guiana (FG) was the first country in South America to declare chikungunya virus infection (CHIKV). The outbreak affected about 16,000 persons between February 2014 and October 2015, with several atypical cases, but only two fatal cases. We aimed to describe the clinical presentation of patients hospitalized for CHIKV infection, to estimate and identify risk factors of unusual and severe forms in adult patients. Read More

View Article
December 2018

Association of pre-eclampsia risk with maternal levels of folate, homocysteine and vitamin B12 in Colombia: A case-control study.

PLoS One 2018 6;13(12):e0208137. Epub 2018 Dec 6.

Farr Institute of Health Informatics, University College London, London, United Kingdom.

Background: Maternal serum concentrations of folate, homocysteine, and vitamin B12 have been associated with pre-eclampsia. Nevertheless, reported studies involve limited number of cases to reliably assess the nature of these associations. Our aim was to examine the relation of these three biomarkers with pre-eclampsia risk in a large Colombian population. Read More

View Article
December 2018
1 Read

Monitoring the elimination of human African trypanosomiasis: Update to 2016.

PLoS Negl Trop Dis 2018 Dec 6;12(12):e0006890. Epub 2018 Dec 6.

World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland.

Background: Human African trypanosomiasis (HAT) is a neglected tropical disease targeted for elimination 'as a public health problem' by 2020. The indicators to monitor progress towards the target are based on the number of reported cases, the related areas and populations exposed at various levels of risk, and the coverage of surveillance activities. Based on data provided by the National Sleeping Sickness Control Programmes (NSSCP), Non-Governmental Organizations (NGOs) and research institutions-and assembled in the Atlas of HAT-the World Health Organization (WHO) provides here an update to 2016 for these indicators, as well as an analysis of the epidemiological situation. Read More

View Article
December 2018
1 Read

Covered perforation of Meckel's diverticulum ulcer to transverse colon: highlighting the urgent intervention and the avoidance of a dramatic evolution (case report and literature review).

Folia Med Cracov 2018 ;58(3):83-87

Department of Internal Medicine, General Hospital of Veria, Veria, Greece.

Meckel's diverticulum represents a remnant of the proximal end of the omphalomesenteric duct, which constitutes a connection between the middle intestine and the vitelline vesicle. It is the most common congenital anomaly of the gastrointestinal tract and is found in approximately 0.3-2% of the general population. Read More

View Article
January 2018

Risk factors for recoarctation of aorta after Norwood procedure in patients with hypoplastic left heart syndrome.

Folia Med Cracov 2018 ;58(3):11-21

Department of Pediatric Cardiac Surgery, University Children's Hospital, Jagiellonian University Medical College, Wielicka 265, Kraków, Poland.

Background: Recoarctation (reCoA) of the aorta is a common complication afer the Norwood procedure. Untreated, it can lead to failure of the systemic ventricle and death. The main goal of the study is to define risk factors of reCoA after the Norwood procedure in hypoplastic left heart syndrome (HLHS). Read More

View Article
January 2018
  • Page 1 of 64571