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    470 results match your criteria Case reports in dermatology[Journal]

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    Epidermolytic Acanthoma on Fingers, Mimicking Flat Warts.
    Case Rep Dermatol 2017 May-Aug;9(2):98-101. Epub 2017 Jul 14.
    Division of Dermatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
    Epidermolytic acanthoma (EA) is a benign cutaneous condition. It is characterized by warty or flat-topped, keratotic papules that show epidermolytic hyperkeratosis in histology. EA has been described to occur in various locations, namely the trunk, face, and genitoscrotal area. Read More

    The Use of Intralesional Steroids in a Case of Localized Pemphigus Foliaceus.
    Case Rep Dermatol 2017 May-Aug;9(2):91-97. Epub 2017 Jul 13.
    Department of Dermatology, Herbert Wertheim College of Medicine, Florida International University, Greater Miami Skin and Laser Center, Miami, Florida, USA.
    A 37-year-old South-Asian male presented to our clinic with a crusty, verrucous-like, scaly plaque of the left ala of the nose. After ruling out infectious and other epidermal bullous diseases, we finalized a diagnosis of localized pemphigus foliaceus, an exceptionally rare disorder with only 15 cases reported in the literature to date. The hyperkeratotic lesions responded favorably to a 3-week regimen of triamcinolone ointment and a onetime intralesional triamcinolone 2. Read More

    Sweet's Syndrome Arising in a Scar.
    Case Rep Dermatol 2017 May-Aug;9(2):86-90. Epub 2017 Jul 13.
    Tripler Army Medical Center, Honolulu, Hawaii, USA.
    Acute febrile neutrophilic dermatosis (Sweet's syndrome) is an uncommon inflammatory cutaneous disorder. It presents with lesions which are tender, erythematous, edematous papules and under histologic examination show dense neutrophilic infiltration of the dermis. These lesions are often accompanied by leukocytosis and fever. Read More

    Extrafacial Granuloma Faciale: A Case Report and Brief Review.
    Case Rep Dermatol 2017 May-Aug;9(2):79-85. Epub 2017 Jul 13.
    Department of Dermatology, Mater Misericordiae Hospital, Brisbane, Queensland, Australia.
    Granuloma faciale (GF) is a rare, inflammatory, cutaneous disorder of unknown aetiology. It presents clinically as one or several well-circumscribed violaceous papules, plaques, and nodules almost exclusively confined to the facial region. Rarely, extrafacial lesions can occur, most often on sun-exposed sites. Read More

    A Disease-Modifying Approach for Advanced Hidradenitis Suppurativa (Regimen with Metformin, Liraglutide, Dapsone, and Finasteride): A Case Report.
    Case Rep Dermatol 2017 May-Aug;9(2):70-78. Epub 2017 Jul 13.
    UNMC Department of Family Medicine, Nebraska Medical Center, Omaha, Nebraska, USA.
    Hidradenitis suppurativa (HS) is a challenging skin disease with limited therapeutic options. Obesity and metabolic syndrome are being increasingly implicated and associated with younger ages and greater metabolic severity. A 19-year-old female with an 8-year history of progressively debilitating cicatricial HS disease presented with obesity, profound anemia, leukocytosis, increased platelet count, hypoalbuminemia, and elevated liver enzymes. Read More

    Wells' Syndrome Successfully Treated with Colchicine.
    Case Rep Dermatol 2017 May-Aug;9(2):65-69. Epub 2017 Jul 13.
    Pathology Department, Complejo Hospitalario Universitario de Pontevedra, EOXI Pontevedra-Salnés, Pontevedra, Spain.
    Eosinophilic cellulitis is an uncommon, inflammatory and chronic disorder of unknown etiology. Corticosteroids are currently considered as the first-line treatment but they are not without significant disadvantages such as contraindications in steroid-resistant cases and patients with frequent recurrences. We report a patient suffering from Wells' syndrome with a 24-year history of symptomatic and generalized skin lesions. Read More

    Scabies Associated with Granulomatous Dermatitis.
    Case Rep Dermatol 2017 May-Aug;9(2):60-64. Epub 2017 Jul 13.
    Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida, USA.
    Scabies is a relatively common parasitic infection, which has sometimes been associated with the formation of granuloma annulare. We report the case of an 86-year-old female who developed a non-necrotizing granulomatous dermatitis after a scabies infestation. This case highlights the importance of considering scabies in the differential diagnosis when granulomatous dermatitis is noted histologically that cannot be explained by other causes. Read More

    Efficacy and Tolerability of Polyphenon E in "Difficult-to-Treat" Multiple Genital Warts in an HIV-Positive Male Subject.
    Case Rep Dermatol 2017 May-Aug;9(2):55-59. Epub 2017 Jun 27.
    Medical Department, Difa Cooper, Caronno, Italy.
    A 55-year-old man, nonsmoker, with a HIV-positive history came to our attention in February 2017. He was on treatment with Stribild(TM), 1 capsule daily (150 mg elvitegravir, 150 mg cobicistat, 200 mg emtricitabine, and 245 mg tenofovir disoproxil). The CD4+/CD8+ cellular count was 326/µL (normal values: 404-1,612); the CD3+/CD8+ cellular count was 819/µL (normal values: 220-1,219). Read More

    Delayed Diagnosis of Basal Cell Carcinoma of the Upper Lip: The Possible Role of Incidental Multinucleated Foreign Body Giant Cells.
    Case Rep Dermatol 2017 May-Aug;9(2):50-54. Epub 2017 Jun 16.
    Department of Dermatology, University of Texas Medical Branch, Galveston, Texas, USA.
    Herpes simplex and basal cell carcinoma (BCC) can have similar clinical presentations due to overlapping lesional morphology. We describe the unusual case of a BCC masquerading as herpes labialis due to a possible false-positive Tzanck smear. The confounding diagnosis led to a failed trial of valacyclovir and subsequent loss of the patient for 1 year before the lesion was biopsied and diagnosed as a BCC. Read More

    Trichoscopic Findings of Erosive Pustular Dermatosis of the Scalp Associated with Gefitinib.
    Case Rep Dermatol 2017 May-Aug;9(2):44-49. Epub 2017 Jun 14.
    Department of Dermatology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
    Alopecia associated with epidermal growth factor receptor (EGFR) inhibitor therapy is a rare cutaneous side effect with the potential to progress to scarring alopecia. Thus, dermatologists should make an early diagnosis. We present the case of a 57-year-old Japanese female with scarring alopecia associated with gefitinib, which is an EGFR inhibitor, including trichoscopic findings. Read More

    Erythema Gyratum Repens-Like Purpura in a Patient with Sjögren Syndrome.
    Case Rep Dermatol 2017 May-Aug;9(2):40-43. Epub 2017 Jun 14.
    Department of Dermatology, Tokyo Medical University, Tokyo, Japan.
    The etiology of purpura in Sjögren syndrome (SS) includes cryoglobulinemia, hypergammaglobulinemia, and leukocytoclastic vasculitis (LCV). The clinical symptoms of LCV associated with SS comprise palpable or nonpalpable purpura and urticarial vasculitis. Here, we report a case of LCV presenting as erythema gyratum repens (EGR)-like purpura in a 62-year-old woman with rheumatoid arthritis and SS. Read More

    Eruptive Seborrheic Keratoses Restricted to Plaque/Patch-Stage Mycosis Fungoides.
    Case Rep Dermatol 2017 May-Aug;9(2):35-39. Epub 2017 Jun 8.
    Department of Dermatology, CHU Sart Tilman, University of Liège, Liège, Belgium.
    Eruptive seborrheic keratoses (ESK) are rare in dermatology. They are usually inflammatory in nature and may be encountered as Leser-Trélat sign. ESK may also be simultaneously observed with hepatic angiomas, chemotherapy, segmental neurofibromatosis, HIV or erythrodermic pityriasis rubra pilaris, psoriasis, and drug eruption. Read More

    A Case of Facial Partial Unilateral Lentiginosis Treated with Low-Fluence 1,064 nm Q-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser.
    Case Rep Dermatol 2017 May-Aug;9(2):30-34. Epub 2017 Jun 1.
    Department of Dermatology, Cheil General Hospital and Women's Healthcare Center, Dankook University College of Medicine, Cheonan, Republic of Korea.
    Partial unilateral lentiginosis (PUL) is an unusual pigmentary disorder characterized by numerous lentigines grouped within an area of normal skin. Although treatment is not necessary, many patients with facial PUL seek medical help for cosmetic reasons. There is no established standard treatment for PUL. Read More

    Infliximab-Induced Aseptic Meningitis during the Treatment of Psoriatic Arthritis.
    Case Rep Dermatol 2017 May-Aug;9(2):26-29. Epub 2017 May 22.
    aDepartment of Dermatology, Shonan Fujisawa Tokushukai Hospital, Fujisawa, Japan.
    A 42-year-old Japanese man presented with persistent headache during treatment for psoriatic arthritis (PsA) with infliximab. Treatment with infliximab was initiated 3 years before and the psoriatic skin lesions with arthritis were well controlled. However, after 21 doses of infliximab, the skin lesions and joint pain exacerbated and became intractable. Read More

    Successful Treatment of Chronic Staphylococcus aureus-Related Dermatoses with the Topical Endolysin Staphefekt SA.100: A Report of 3 Cases.
    Case Rep Dermatol 2017 May-Aug;9(2):19-25. Epub 2017 May 22.
    Department of Dermatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.
    Staphylococcus aureus plays an important role in skin and soft tissue infections and contributes to the pathophysiology of complex skin disorders such as atopic dermatitis. Bacterial resistance against commonly used antibiotics has increased considerably in the last decades demanding alternative treatment approaches. We present 3 cases where patients with chronic and recurrent S. Read More

    Sweet's Syndrome Successfully Treated with Granulocyte and Monocyte Adsorption Apheresis.
    Case Rep Dermatol 2017 May-Aug;9(2):13-18. Epub 2017 May 22.
    aDepartment of Dermatology, Gifu University Graduate School of Medicine, Gifu, Japan.
    Sweet's syndrome is a neutrophilic dermatosis characterized by an abrupt onset of painful erythematous lesions showing neutrophilic infiltrates in the dermis. Fever and an elevated neutrophil level are generally observed. Sweet's syndrome may be idiopathic, malignancy-associated, or drug-induced (mainly involving granulocyte colony-stimulating factor (G-CSF) administration). Read More

    Cutaneous Corynebacterium Infection Presenting with Disseminated Skin Nodules and Ulceration.
    Case Rep Dermatol 2017 May-Aug;9(2):8-12. Epub 2017 May 16.
    aDepartment of Dermatology, University Hospital Zurich, Zurich, Switzerland.
    In the context of the European migrant crisis, more and more cases of cutaneous diphtheria are seen. A typical presentation includes painful cutaneous ulcerations with grayish-whitish pseudomembranes. Here we present 2 male Eritrean patients suffering from cutaneous nontoxigenic Corynebacterium diphtheriae (patient 1) and Corynebacterium striatum (patient 2) infection. Read More

    Overlapping DRESS and Stevens-Johnson Syndrome: Case Report and Review of the Literature.
    Case Rep Dermatol 2017 May-Aug;9(2):1-7. Epub 2017 May 8.
    Department of Dermatology and Venereology, Erasme Hospital, ULB, Brussels, Belgium.
    Drug-induced severe cutaneous adverse reactions (SCARs) include acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS), and epidermal necrolysis (Stevens-Johnson syndrome [SJS], toxic epidermal necrolysis). The identification of the causal drug is crucial in order to avoid further exposure, but making the right differential diagnosis of the type of SCAR is equally important since treatment, follow-up, and prognosis of different SCARs are not the same. These syndromes are distinct entities with different clinical, biological, and histological patterns, but sometimes the early distinction between 2 SCARs can be extremely challenging, and overlapping conditions could therefore be taken into consideration, although true overlapping SCARs are very rare when using strict diagnostic criteria (described by the RegiSCAR group). Read More

    Panniculitis Associated with MEK Inhibitor Therapy: An Uncommon Adverse Effect.
    Case Rep Dermatol 2017 Jan-Apr;9(1):80-85. Epub 2017 Mar 21.
    aDepartment of Dermatology, Université Paul Sabatier-Toulouse III et Institut Universitaire du Cancer de Toulouse, Toulouse, France.
    The combination of MEK inhibitor (cobimetinib, trametinib) and BRAF inhibitor (vemurafenib, dabrafenib) is now the first-line treatment in patients with BRAF V600-mutated metastatic melanoma. This association reduces cutaneous adverse events induced by BRAF inhibitors alone, including photosensitivity, hand-foot syndrome, hyperkeratosis, alopecia, skin papillomas, keratoacanthomas, and squamous-cell carcinomas. While panniculitis has exceptionally been reported with BRAF inhibitors, this rare side effect has never been described with the use of MEK inhibitors. Read More

    Angioimmunoblastic T-Cell Lymphoma Mimicking Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS Syndrome).
    Case Rep Dermatol 2017 Jan-Apr;9(1):74-79. Epub 2017 Mar 21.
    aDepartment of Dermatology, University Hospital Zurich, Zurich, Switzerland.
    Angioimmunoblastic T-cell lymphoma (AITCL) is a rare, aggressive lymphoma which derives from follicular helper T cells, commonly affecting the elderly population. It accounts for 2% of all non-Hodgkin lymphomas, with a reported 5-year overall survival rate of less than 30%. Very often, the clinical picture of AITCL encompasses systemic symptoms such as generalized lymphadenopathy, hepatosplenomegaly, skin rash, anemia, and polyclonal hypergammaglobulinemia. Read More

    Necrolytic Acral Erythema in Seronegative Hepatitis C.
    Case Rep Dermatol 2017 Jan-Apr;9(1):69-73. Epub 2017 Mar 17.
    Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
    Necrolytic acral erythema (NAE) is a distinctive skin disorder. The exact cause and pathogenesis is still unclear. Most studies report an association of NAE with hepatitis C virus (HCV) infection. Read More

    Flare-Up of Rheumatoid Arthritis by Anti-CTLA-4 Antibody but Not by Anti-PD1 Therapy in a Patient with Metastatic Melanoma.
    Case Rep Dermatol 2017 Jan-Apr;9(1):65-68. Epub 2017 Mar 9.
    aDepartment of Dermatology, University Hospital of Zürich, Zurich, Switzerland.
    A 47-year-old female patient with rheumatoid arthritis (RA) treated with methotrexate, was diagnosed with metastatic melanoma. After surgical removal of the tumor, the patient started treatment with ipilimumab while methotrexate was stopped. One week after initiation of ipilimumab, the patient developed typical symptoms of RA. Read More

    Visual Loss Induced by Adalimumab Used for Plaque Psoriasis.
    Case Rep Dermatol 2017 Jan-Apr;9(1):60-64. Epub 2017 Mar 3.
    Maimonides Medical Center, Brooklyn, New York, USA.
    A 61-year-old Caucasian male with severe plaque psoriasis without joint involvement was initiated on adalimumab therapy. Shortly thereafter he presented to the emergency room with acute loss of vision in the right eye. A comprehensive systemic workup was instituted which included magnetic resonance imaging (MRI) with and without gadolinium of the brain and orbits. Read More

    Psoriatic Alopecia in a Patient with Systemic Lupus Erythematosus.
    Case Rep Dermatol 2017 Jan-Apr;9(1):51-59. Epub 2017 Mar 3.
    Division of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
    Psoriasis is a chronic, recurrent, and relatively common inflammatory dermatologic condition, which demonstrates various clinical manifestations including hair loss. It was once believed that alopecia was not a presentation of scalp psoriasis, but it is now widely accepted that psoriatic alopecia exists. Although the majority of patients get hair regrowth, it can potentially lead to permanent hair loss. Read More

    Pruritic Urticarial Papules and Plaques of Pregnancy Occurring Postpartum Treated with Intramuscular Injection of Autologous Whole Blood.
    Case Rep Dermatol 2017 Jan-Apr;9(1):151-156. Epub 2017 Apr 27.
    Department of Dermatology, Cheil General Hospital and Women's Healthcare Center, Dankook University College of Medicine, Cheonan, Republic of Korea.
    Pruritic urticarial papules and plaques of pregnancy (PUPPP) is one of the most common diseases associated with pregnancy. In most cases, the skin lesions develop in the third trimester of primigravidas. There are no systemic alterations seen in PUPPP; however, most patients report severe pruritus. Read More

    The Rare Case of Pemphigus Vegetans in Association with Malnutrition Children in the Multidisciplinary Management.
    Case Rep Dermatol 2017 Jan-Apr;9(1):145-150. Epub 2017 Apr 27.
    Division of Allergy-Immunology, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Bandung, Indonesia.
    Pemphigus vegetans is a clinical variant of pemphigus vulgaris, accounting for 1-2% of all very rare pemphigus cases in children. The involvement of the oral mucosa in this disease is usually accompanied by severe pain that aggravates the patient's malnourished condition. Conversely, malnutrition may also reduce vulnerability towards autoimmune diseases. Read More

    Interruption of Sneddon-Wilkinson Subcorneal Pustulation with Infliximab.
    Case Rep Dermatol 2017 Jan-Apr;9(1):140-144. Epub 2017 Apr 27.
    aDepartment of Dermatology, University Hospital of Zurich, Zurich, Switzerland.
    Subcorneal pustular dermatosis (SCPD, Sneddon-Wilkinson disease) is a rare chronic-relapsing skin disorder that typically manifests as flaccid sterile pustules without systemic symptoms. Although the accumulation of neutrophils is acknowledged to be a hallmark of SCPD, its exact pathomechanism is still not known. Several chemotactic factors have been implicated in neutrophil recruitment and invasion, including the proinflammatory cytokine TNF-α. Read More

    Rapid Involution of Pustules during Topical Steroid Treatment of Acute Generalized Exanthematous Pustulosis.
    Case Rep Dermatol 2017 Jan-Apr;9(1):135-139. Epub 2017 Apr 27.
    Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland.
    Acute generalized exanthematous pustulosis (AGEP) is a dramatic generalized pustular rash of severe onset, which is considered a serious cutaneous adverse reaction to drugs. However, even though the clinical features are impressive and are often accompanied by systemic inflammation, it can be controlled quickly and safely by topical steroids subsequent to interruption of the offending drug. Here, we describe the management of a case and the evolution of the pustular rash. Read More

    Isolated Actinic Lichen Planus of the Lower Lip.
    Case Rep Dermatol 2017 Jan-Apr;9(1):131-134. Epub 2017 Apr 27.
    National University Hospital, Singapore, Singapore.
    Oral lichen planus (LP) is a common manifestation in patients with LP; however, isolated lip LP is rare and may mimic other conditions such as lichenoid drug eruptions, actinic cheilitis, and early carcinoma in situ in the absence of typical skin lesions. Actinic lichen planus (ALP) is a variant of LP occurring on light-exposed areas in patients with dark skin. We report the case of a Chinese female with isolated ALP of the lower lip, mimicking herpes simplex infection at presentation. Read More

    Atypical Clinical and Serological Manifestation of Pemphigus Vegetans: A Case Report and Review of the Literature.
    Case Rep Dermatol 2017 Jan-Apr;9(1):121-130. Epub 2017 Apr 27.
    aDepartment of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.
    Pemphigus vegetans (PVeg) is a rare variant of pemphigus vulgaris characterized by pustules and/or papillomatous vegetations, preferentially affecting intertriginous and periorificial areas. Exceptional manifestations may be misdiagnosed resulting in delayed diagnosis and treatment. Diagnosis is confirmed by immunofluorescence and detection of anti-desmoglein (Dsg) 3 and/or anti-Dsg1 antibodies. Read More

    Fuchs Syndrome: Medical Treatment of 1 Case and Literature Review.
    Case Rep Dermatol 2017 Jan-Apr;9(1):114-120. Epub 2017 Apr 18.
    Department of Odontology, University Hospital of Montpellier, Montpellier, France.
    Fuchs syndrome is a particular type of erythema multiforme major; the lesions are only found on the mucosae and specifically affect oral, ocular, and genital mucosae. The cause is not always immediately apparent, which is why this pathology requires a rigorous, detailed clinical examination to eliminate a differential diagnosis. The severity of the symptoms, particularly of oral and ocular symptoms, requires immediate treatment. Read More

    A Case of Subcutaneous Sarcoidosis Occurring along the Superficial Veins of the Forearms: A Distinctive Cutaneous Manifestation Masquerading Venous Tropic Action in the Underlying Systemic Disease?
    Case Rep Dermatol 2017 Jan-Apr;9(1):108-113. Epub 2017 Apr 7.
    aDepartment of Dermatology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
    Sarcoidosis is a multisystem disease of unknown etiology, developing granulomas in any tissues and organs. Approximately 25% of sarcoidosis patients have cutaneous involvement with various clinical manifestations, which are categorized into specific or nonspecific diseases based on the histopathology; the former represents the typical sarcoid granulomas. Subcutaneous sarcoidosis is one of the specific skin lesions and often affects extremities, to a much lesser extent with other anatomical sites. Read More

    Concomitant B Hairy Cell Leukemia and Mycosis Fungoides in an Elderly Man.
    Case Rep Dermatol 2017 Jan-Apr;9(1):103-107. Epub 2017 Apr 7.
    aDivision of Dermatology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
    The development of both a T- and B-cell lymphoproliferative disorder in one patient is an unlikely coincidence due to the low prevalence of each malignancy. We report a 65-year-old man with a previously documented history of B hairy cell leukemia, who presented with a new-onset acneiform eruption of his scalp, face, trunk, back, and extremities. Routine pathology of the skin lesions with immunohistochemical stains and molecular studies were consistent with a folliculotropic mycosis fungoides. Read More

    Painful Leg Ulceration in a Poorly Controlled Hypertensive Patient: A Case Report of Martorell Ulcer.
    Case Rep Dermatol 2017 Jan-Apr;9(1):95-102. Epub 2017 Apr 7.
    bFiona Stanley Hospital, Murdoch, WA, Australia.
    Martorell ulcer is a form of lower limb ulceration, preceded by a small area of excruciating pain. It often appears as a solitary lesion on the outer aspect of the lower limb, and is primarily associated with poorly controlled hypertension and diabetes. Treatment of the ulcer involves awareness and early correct diagnosis, adequate control of blood pressure, management of infection, and wound care. Read More

    Papulonodular Secondary Syphilis Presenting as Multiple Distinct Cutaneous Lesions in an HIV-Positive Transgender Woman.
    Case Rep Dermatol 2017 Jan-Apr;9(1):90-94. Epub 2017 Mar 29.
    Department of Dermatology, Weill Cornell Medical College, New York, New York, USA.
    We present the first reported case of papulonodular secondary syphilis in an HIV-positive transgender female. Syphilis is classified into primary, secondary, latent, and tertiary stages, with secondary syphilis having notably diverse cutaneous manifestations. Our patient presented with diverse lesions throughout her body, all pathologically consistent with papulonodular secondary syphilis. Read More

    Unilateral Linear Punctate Palmoplantar Keratoderma: A Case Report.
    Case Rep Dermatol 2017 Jan-Apr;9(1):86-89. Epub 2017 Mar 29.
    bAtopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
    Punctate palmoplantar keratoderma (PPPK) is a rare entity with an estimated prevalence rate of 1.17/100,000. PPPK usually presents with bilateral asymptomatic, tiny, hyperkeratotic punctate papules and plaques on the palmoplantar surface. Read More

    Refractory Cutaneous IgA Vasculitis Treated with Omega-3 Fatty Acids.
    Case Rep Dermatol 2016 Sep-Dec;8(3):333-340. Epub 2016 Nov 29.
    Department of Nephrology, Fundació Puigvert, Barcelona, Spain.
    Background: Omega-3 fatty acids (O3FA) have been used to treat IgA nephropathy (IgAN) but not cutaneous IgA vasculitis (IgAV).

    Case Report: A 47-year-old female was referred for cutaneous vasculitis. She had a 24-year history of flares of palpable purpura, arthralgia associated with hematuria, and proteinuria. Read More

    A Case Report of Cushing's Disease Presenting as Hair Loss.
    Case Rep Dermatol 2017 Jan-Apr;9(1):45-50. Epub 2017 Feb 21.
    Department of Dermatology, Roger Williams Medical Center, Providence, RI, USA.
    Cushing's syndrome is a rare endocrine disorder that comprises a large group of signs and symptoms resulting from chronic exposure to excess corticosteroids. Most cases of Cushing's syndrome are due to increased adrenocorticotropic hormone production from a pituitary adenoma, which is referred to as Cushing's disease. Most of the signs and symptoms are nonspecific and common in the general population, making a diagnosis often challenging. Read More

    Successful Treatment of a Bullous Pemphigoid Patient with Rituximab Who Was Refractory to Corticosteroid and Omalizumab Treatments.
    Case Rep Dermatol 2017 Jan-Apr;9(1):38-44. Epub 2017 Feb 10.
    Akdeniz University Faculty of Medicine, Dermatology and Venereology Department, Antalya, Turkey.
    Omalizumab is a humanized monoclonal antibody which is an FDA-approved treatment of severe allergic asthma and inhibits IgE binding to FcεRI. According to increasing evidence of IgE inhibition, omalizumab was suggested as a therapeutic approach for bullous pemphigoid (BP). Rituximab has been reported to be effective in various autoimmune diseases, including autoimmune bullous dermatoses. Read More

    Severe, Malignant Acanthosis Nigricans Associated with Adenocarcinoma of the Endometrium in a Young Obese Female.
    Case Rep Dermatol 2017 Jan-Apr;9(1):30-37. Epub 2017 Feb 10.
    Department of Dermatology, Mater Misericordiae Hospital, Brisbane, QLD, Australia.
    Acanthosis nigricans (AN) is a dermatopathy associated with insulin-resistance, drugs, endocrine disorders, chromosomal abnormalities (benign AN), and neoplasia (malignant AN). Malignant AN (MAN) is a rare paraneoplastic skin syndrome most commonly associated with gastric adenocarcinoma and other intra-abdominal malignancies. We report the case of a 28-year-old female with AN associated with obesity, insulin resistance, and endometrial adenocarcinoma. Read More

    Calciphylaxis Presenting with Various Symptoms: A Case Report.
    Case Rep Dermatol 2017 Jan-Apr;9(1):25-29. Epub 2017 Feb 8.
    Department of Dermatology, School of Medicine, Iwate Medical University, Morioka, Japan.
    Calciphylaxis causes ischemia in multiple organs and skin ulcers owing to progressive calcification in small and medial arteries. It has a poor prognosis and often occurs in patients with hyperparathyroidism associated with end-stage renal failure and those undergoing hemodialysis. Here, we present a case of calciphylaxis associated with a wide range of symptoms, including lower thigh skin ulcers, a rectovaginal fistula, and femoral neck fracture. Read More

    Psoriasiform Diaper Rash Possibly Induced by Oral Propranolol in an 18-Month-Old Girl with Infantile Hemangioma.
    Case Rep Dermatol 2016 Sep-Dec;8(3):369-373. Epub 2016 Dec 22.
    Department of Dermatology, Centre Hospitalier de Saint-Brieuc, Saint-Brieuc, France.
    Propranolol, a nonselective blocker of β-adrenergic receptors, has become the first-line treatment for complicated infantile hemangiomas. Therefore, its use in the pediatric population has expanded in recent years. In adults, β-blockers have been reported to be the most common causative agents for drug-induced psoriasis. Read More

    Unilateral Idiopathic Calcinosis Cutis: A Case Report.
    Case Rep Dermatol 2017 Jan-Apr;9(1):20-24. Epub 2017 Jan 27.
    Department of Dermatology, King Saud Medical City, Riyadh, Saudi Arabia.
    Calcinosis cutis is a rare disorder characterized by the deposition of calcium in the skin and subcutaneous tissue. Unilateral idiopathic calcinosis cutis has only rarely been reported in the literature. Here, we report the case of a 7-year-old healthy girl who presented with multiple asymptomatic hard nodules on the right side of her body. Read More

    A 28-Year-Old Male Patient with Nail Tumors, Skin Lesions, and Epilepsy.
    Case Rep Dermatol 2017 Jan-Apr;9(1):12-19. Epub 2017 Jan 26.
    Department of Dermatology, Reinier de Graaf Gasthuis, Delft, The Netherlands.
    Background: Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by the development of benign hamartomas in multiple organs. Most patients with TSC exhibit cutaneous manifestations.

    Methods: We report a 28-year-old patient with multiple pink papules at the proximal nail fold of several toes. Read More

    Azathioprine Hypersensitivity Syndrome: Two Cases of Febrile Neutrophilic Dermatosis Induced by Azathioprine.
    Case Rep Dermatol 2017 Jan-Apr;9(1):6-11. Epub 2017 Jan 19.
    Paul Sabatier University, University Hospitals of Toulouse, Toulouse, France; Department of Dermatology, University Hospitals of Toulouse, Toulouse, France.
    Background: Azathioprine is an immunosuppressive agent used in the treatment of immune-mediated diseases. Azathioprine hypersensitivity syndrome is a rare adverse reaction occurring a few days to weeks after the administration of azathioprine.

    Case 1: A 36-year-old male with ulcerative colitis presented with erythematous plaques, pustules and erosions on the lower back, buttocks and thighs associated with high fever (39°C) 2 weeks after the initiation of azathioprine 100 mg/day. Read More

    Papular Epidermal Nevus with "Skyline" Basal Cell Layer Syndrome - Natural Course: Case Report and Literature Review.
    Case Rep Dermatol 2017 Jan-Apr;9(1):1-5. Epub 2017 Jan 10.
    Department of Dermatology, University Hospital Basel, Basel, Switzerland; Department of Biomedicine, University Hospital Basel, Basel, Switzerland.
    Papular epidermal nevus with "skyline" basal cell layer (PENS) is a very rare type of keratinocytic nevus and is associated with extracutaneous findings such as neurological symptoms in about 50% of the cases. Therefore, it is also referred to as PENS syndrome. Clinically visible hyperkeratotic papules and plaques already appear at birth or shortly thereafter, while neurological symptoms such as epilepsy and mental retardation manifest themselves during childhood. Read More

    Giant Basal Cell Carcinomas Arising on the Bilateral Forearms of a Patient: A Case Report and Review of Nonsurgical Treatment Options.
    Case Rep Dermatol 2016 Sep-Dec;8(3):363-368. Epub 2016 Dec 13.
    Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
    Giant basal cell carcinomas (GBCCs) are large basal cell carcinomas (BCCs; <5 cm) with a greater propensity to invade and metastasize than standard BCCs. The presence of 2 GBCCs in a single individual is rare. We present the case of a 71-year-old Caucasian male with bilateral GBCCs on the dorsal forearms, measuring 130 cm(2) and 24 cm(2), respectively, that developed over a 21-year period. Read More

    Bazex Syndrome in Lung Squamous Cell Carcinoma: High Expression of Epidermal Growth Factor Receptor in Lesional Keratinocytes with Th2 Immune Shift.
    Case Rep Dermatol 2016 Sep-Dec;8(3):358-362. Epub 2016 Dec 8.
    Department of Dermatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
    An 82-year-old Japanese man was referred for detailed examination of hyperkeratotic erythematous plaques on his palms and soles for 6 months. Two weeks before his first visit, he had undergone lung lobectomy for right lung squamous cell carcinoma (SCC). Laboratory findings showed elevations of eosinophil counts, serum IgE, thymus and activation-regulated chemokine, SCC antigen, and soluble interleukin-2 receptor levels. Read More

    Pyoderma Gangrenosum and Erythema Nodosum Revealing Takayasu's Arteritis.
    Case Rep Dermatol 2016 Sep-Dec;8(3):354-357. Epub 2016 Dec 7.
    University Hospital Basel, Basel, Switzerland; University of Basel, Basel, Switzerland.
    We report a Caucasian female who presented with simultaneous erythema nodosum and pyoderma gangrenosum due to underlying Takayasu's arteritis. Takayasu's arteritis is a chronic large vessel vasculitis of unknown cause. The disease has a worldwide distribution but is most commonly seen in Asian populations. Read More

    Necrobiotic Xanthogranuloma in a Patient with Multiple Myeloma.
    Case Rep Dermatol 2016 Sep-Dec;8(3):350-353. Epub 2016 Dec 1.
    Department of Dermatology, Municipal Hospital Hietzing, Vienna, Austria.
    An 82-year-old woman presented with a 9-month history of multiple, well-defined skin lesions on her neck and upper chest, progressively increasing in size. Histological examination of a skin biopsy showed a regular epidermis. In the dermis, granulomatous changes with central necrobiosis were found which extended focally into the subcutaneous fat. Read More

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