3,232,422 results match your criteria Case reports in dermatology[Journal]


[Evolution of the incidence of colonized and infected patients by VIM carbapenemase-producing bacteria in a pediatric hospital in Spain].

Rev Esp Quimioter 2018 Dec 13. Epub 2018 Dec 13.

Raquel González Rubio, Escuela Nacional de Sanidad. C/Sinesio Delgado 10, 28029 Madrid. Spain.

Objective: The aim of this study is to describe the evolution of the incidence of infected and colonized patients with carbapenemase VIM-producing bacteria (CPB-VIM) at a national referral pediatric center in Madrid, Spain, between 2012 and 2015.

Methods: Descriptive epidemiological surveillance study. The surveillance system included case detection (screening for BPC colonization in all admitted patients, with periodicity according to the ward) and control measures (contact precautions, identification of previously colonized patients at admission, environmental cleaning, education, supervision of contact precautions, and patient cohort). Read More

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December 2018

A 9-months multidisciplinary rehabilitation protocol based on early post-operative mobilization following a chronic-degenerative patellar tendon rupture in a professional soccer player: a case report.

Eur J Phys Rehabil Med 2018 Dec 14. Epub 2018 Dec 14.

IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

Background: Isolated patellar tendon rupture (PTR) is the final stage of a long-standing tendon chronic degeneration. PTR requires immediate repair in order to avoid important muscle retraction and tendon fibrosis. The aim was to describe the effects of a rehabilitation protocol after chronic-degenerative PTR on subjective functional outcomes, knee range of motion (ROM), size, and strength in a professional football player. Read More

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December 2018

Heter-LP: A Heterogeneous Label Propagation Method for Drug Repositioning.

Methods Mol Biol 2019 ;1903:291-316

Department of Systems and Computer Engineering, Carleton University, Ottawa, ON, Canada.

Using existing drugs for diseases which are not developed for their treating (drug repositioning) provides a new approach to developing drugs at a lower cost, faster, and more secured. We proposed a method for drug repositioning which can predict simple and complex relationships between drugs, drug targets, and diseases. Since biological networks typically present a suitable model for relationships between different biological concepts, our primary approach is to analyze graphs and complex networks in the study of drugs and their therapeutic effects. Read More

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January 2019

A Machine-Learning-Based Drug Repurposing Approach Using Baseline Regularization.

Methods Mol Biol 2019 ;1903:255-267

The University of Wisconsin, Madison, WI, USA.

We present the baseline regularization model for computational drug repurposing using electronic health records (EHRs). In EHRs, drug prescriptions of various drugs are recorded throughout time for various patients. In the same time, numeric physical measurements (e. Read More

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January 2019

Computational Prediction of Drug-Target Interactions via Ensemble Learning.

Methods Mol Biol 2019 ;1903:239-254

Division of Software and Information Systems, School of Computer Science and Engineering, Nanyang Technological University, Singapore, Singapore.

Therapeutic effects of drugs are mediated via interactions between them and their intended targets. As such, prediction of drug-target interactions is of great importance. Drug-target interaction prediction is especially relevant in the case of drug repositioning where attempts are made to repurpose old drugs for new indications. Read More

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January 2019

Transcriptomic Data Mining and Repurposing for Computational Drug Discovery.

Methods Mol Biol 2019 ;1903:73-95

Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Conventional drug discovery in general is costly and time-consuming with extremely low success and relatively high attrition rates. The disparity between high cost of drug discovery and vast unmet medical needs resulted in advent of an increasing number of computational approaches that can "connect" disease with a candidate therapeutic. This includes computational drug repurposing or repositioning wherein the goal is to discover a new indication for an approved drug. Read More

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January 2019
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Methods for Discovering and Targeting Druggable Protein-Protein Interfaces and Their Application to Repurposing.

Methods Mol Biol 2019 ;1903:1-21

Department of Chemical and Biological Engineering, Koc University, Istanbul, Turkey.

Drug repurposing is a creative and resourceful approach to increase the number of therapies by exploiting available and approved drugs. However, identifying new protein targets for previously approved drugs is challenging. Although new strategies have been developed for drug repurposing, there is broad agreement that there is room for further improvements. Read More

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January 2019

Statistical Network Inference for Time-Varying Molecular Data with Dynamic Bayesian Networks.

Methods Mol Biol 2019 ;1883:25-48

German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.

In this chapter, we review the problem of network inference from time-course data, focusing on a class of graphical models known as dynamic Bayesian networks (DBNs). We discuss the relationship of DBNs to models based on ordinary differential equations, and consider extensions to nonlinear time dynamics. We provide an introduction to time-varying DBN models, which allow for changes to the network structure and parameters over time. Read More

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January 2019

Chromoblastomycosis Caused by Fonsecaea nubica: First Report in Northern China and Literature Review.

Mycopathologia 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatovenereology, West China Hospital, Sichuan University, No. 37, Guo Xue Xiang, Wuhou District, Chengdu, 610041, Sichuan Province, China.

Chromoblastomycosis is found worldwide with higher incidence in tropical and subtropical regions. Fonsecaea spp. is one of the major causative agents of this disease. Read More

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December 2018

Relationship of leptin, growth hormone, and insulin-like growth factor levels with body mass index and disease severity in patients with fibromyalgia syndrome.

Acta Neurol Belg 2018 Dec 13. Epub 2018 Dec 13.

Physical Medicine and Rehabilitation Clinic, Bingöl State Hospital, Bingöl, Turkey.

Objective: A high prevalence of obesity in fibromyalgia syndrome (FMS) predisposes patients to metabolic changes. It is not clear how the clinical manifestations of the disease affect metabolism. This study aimed to investigate leptin, growth hormone (GH), and insulin-like growth factor (IGF-1) levels in FMS, and their relationship with body mass index (BMI) and disease severity. Read More

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December 2018

Pembrolizumab for Locally Advanced or Metastatic Urothelial Cancer Where Cisplatin is Unsuitable: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.

Pharmacoeconomics 2018 Dec 13. Epub 2018 Dec 13.

University College London Hospitals NHS Foundation Trust, London, UK.

As part of its Single Technology Appraisal (STA) process, the National Institute for Health and Care Excellence (NICE) invited the manufacturer (Merck Sharp & Dohme) of pembrolizumab (Keytruda) to submit evidence of its clinical and cost effectiveness for the treatment of locally advanced or metastatic urothelial cancer where cisplatin is unsuitable. The School of Health and Related Research Technology Appraisal Group at the University of Sheffield was commissioned to act as the independent Evidence Review Group (ERG). The ERG produced a detailed review of the evidence for the clinical and cost effectiveness of the technology, based on the company's submission (CS) to NICE. Read More

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December 2018

Obinutuzumab in Combination with Chemotherapy for the First-Line Treatment of Patients with Advanced Follicular Lymphoma : An Evidence Review Group Evaluation of the NICE Single Technology Appraisal.

Pharmacoeconomics 2018 Dec 13. Epub 2018 Dec 13.

Institute of Health Policy and Management/Institute for Medical Technology Assessment, Erasmus University, Rotterdam, The Netherlands.

The National Institute for Health and Care Excellence (NICE), as part of the institute's single technology appraisal (STA) process, invited the company that makes obinutuzumab (Roche Products Limited) to submit evidence of the clinical and cost effectiveness of the drug in combination with chemotherapy, with or without obinutuzumab as maintenance therapy for adult patients with untreated, advanced follicular lymphoma (FL) in the UK. Kleijnen Systematic Reviews Ltd (KSR), in collaboration with Erasmus University Rotterdam, was commissioned to act as the Evidence Review Group (ERG). This paper describes the company's submission, the ERG review, and NICE's subsequent decisions. Read More

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December 2018

Low serum folic acid can be a potential independent risk factor for erectile dysfunction: a prospective case-control study.

Int Urol Nephrol 2018 Dec 13. Epub 2018 Dec 13.

Andrology & STDs Department, Kasr Al-Ainy Faculty of Medicine, Cairo University, Giza, Egypt.

Purpose: The purpose of the study was to compare serum level of folic acid (FA) in patients with erectile dysfunction (ED) versus healthy controls and to assess its correlation with other well-known confounders for ED.

Methods: Our prospective study compared FA in 60 patients with ED versus 30 healthy controls. Patients were excluded if they had any hormonal disorders, Peyronie's disease, or decompensated systemic illnesses. Read More

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December 2018

Anaerobic treatment of residuals from tanks transporting food and fodder.

Environ Sci Pollut Res Int 2018 Dec 13. Epub 2018 Dec 13.

Faculty of Agricultural and Environmental Sciences, University of Rostock, Justus-von-Liebig-Weg 6, 18059, Rostock, Germany.

The anaerobic digestion of wastewater from the cleaning of tank cars transporting food and fodder was investigated in both bench and pilot scales with a single-stage, mesophilic (39 °C), completely mixed process. The promising results lead to the planning and building of a 1200-m full-scale biogas plant at TS-Clean cleaning station in Fahrbinde, Germany. Due to softened water used in the cleaning of the car tanks, the alkalinity in the digester decreased as predicted by the physicochemical model developed for this treatment process. Read More

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December 2018
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Desalination and removal of pesticides from surface water in Mekong Delta by coupling electrodialysis and nanofiltration.

Environ Sci Pollut Res Int 2018 Dec 13. Epub 2018 Dec 13.

Institut Européen des Membranes-IEM, UMR-5635, ENSCM, CNRS, Univ Montpellier, Montpellier, France.

The shortage of drinking water is a major problem in the rural areas of the Mekong Delta, especially, when surface water, a main local direct drinking water source is being threatened by pesticide pollution and salinity intrusion. A hybrid process coupling electrodialysis (ED) and nanofiltration (NF) is proposed as an effective process easy to setup in a small plant to treat complex matrix with high salinity and pesticide concentration as is the Mekong Delta surface water. Performance of the ED-NF integration was evaluated with synthetic solutions based on the comparison with a single NF step generally used for pesticide removal. Read More

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December 2018

Depression, ART Adherence, and Receipt of Case Management Services by Adults with HIV in North Carolina, Medical Monitoring Project, 2009-2013.

AIDS Behav 2018 Dec 13. Epub 2018 Dec 13.

North Carolina Department of Health and Human Services, Division of Public Health, Communicable Disease Branch, Raleigh, NC, 27603, USA.

Depression among persons with HIV is associated with antiretroviral therapy (ART) interruption and discontinuation, virological failure, and poor clinical and survival outcomes. Case management services can address needs for emotional counseling and other supportive services to facilitate HIV care engagement. Using 2009-2013 North Carolina Medical Monitoring Project data from 910 persons engaged in HIV care, we estimated associations of case management utilization with "probable current depression" and with 100% ART dose adherence. Read More

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December 2018

Health Care Facility Characteristics are Associated with Variation in Human Immunodeficiency Virus Pre-exposure Prophylaxis Initiation in Veteran's Health Administration.

AIDS Behav 2018 Dec 13. Epub 2018 Dec 13.

VA Puget Sound Health Care System, Health Services Research and Development, Seattle, WA, USA.

To quantify health care facility-level variation in pre-exposure prophylaxis (PrEP) use in the Veteran's Health Administration (VHA); to identify facility characteristics associated with PrEP use. Retrospective analysis of the health care facility-level rate of PrEP initiation in VHA through June 30, 2017. Standardized PrEP initiation rates were used to rank facilities. Read More

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December 2018

Opening-wedge osteotomies of the distal femur: minor advantages for a biplanar compared to a uniplanar technique.

Knee Surg Sports Traumatol Arthrosc 2018 Dec 13. Epub 2018 Dec 13.

Institute of Biomechanics, Paracelsus Medical University Salzburg, Strubergasse 21, 5020, Salzburg, Austria.

Purpose: Valgus malalignment of the distal femur may be treated with corrective osteotomy. The purpose of this study was to compare the primary stability of a lateral opening-wedge osteotomy (LOWO) using a uniplanar compared to a biplanar technique. A study was carried out to test both surgeries, with both an intact medial cortex and with a deliberate attached cut of the medial cortex simulating a fracture. Read More

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December 2018

Laparoscopic Roux-En-Y Fistulo-Jejunostomy, a Preferred Technique after Failure of Endoscopic and Radiologic Management of Fistula Post Sleeve Gastrectomy.

Obes Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Digestive Surgery, Archet II Hospital, University of Nice-Sophia-Antipolis, 151 Route de Saint-Antoine, 06200, Nice, France.

Background: Laparoscopic sleeve gastrectomy represents the most performed bariatric procedure in France. Staple line leak is the major short-term complication of the procedure. Patients with persistent fistula after sleeve gastrectomy, after failure of endoscopic and radiological treatment, are candidates for salvage surgery. Read More

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December 2018

Preytaxis and Travelling Waves in an Eco-epidemiological Model.

Bull Math Biol 2018 Dec 13. Epub 2018 Dec 13.

Centre for Mathematical Biology, Department of Mathematical Sciences, University of Bath, Bath, BA2 7AY, UK.

Preytaxis is the attraction (or repulsion) of predators along prey density gradients and a potentially important mechanism for predator movement. However, the impact preytaxis has on the spatial spread of a predator invasion or of an epidemic within the prey has not been investigated. We investigate the effects preytaxis has on the wavespeed of several different invasion scenarios in an eco-epidemiological system. Read More

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December 2018

Prophylactic treatment of migraine with and without aura with acetyl-DL-leucine: a case series.

J Neurol 2018 Dec 13. Epub 2018 Dec 13.

Department of Neurology, Ludwig Maximilians University, Munich, Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.

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December 2018

Low-level laser therapy versus trunk stabilization exercises on sternotomy healing after coronary artery bypass grafting: a randomized clinical trial.

Lasers Med Sci 2018 Dec 13. Epub 2018 Dec 13.

Department of Physical Therapy for Internal Medicine, Faculty of Physical Therapy, Cairo University, Giza, Egypt.

The aim of this study was to investigate the effects of low-level laser therapy (LLLT) versus trunk stabilization exercises on sternotomy healing following coronary artery bypass grafting (CABG) surgery. Forty-five male patients who had acute sternal instability post-CABG surgery in the age range of 45-65 years were divided randomly into three equal groups (n = 15). The laser group received LLLT, while the exercise group received trunk stabilization exercises. Read More

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December 2018
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The Influence of a Xanthine-Catechin Chemical Matrix on in vitro Macrophage-Activation Triggered by Antipsychotic Ziprasidone.

Inflammation 2018 Dec 14. Epub 2018 Dec 14.

Postgraduate Program of Pharmacology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil.

Ziprasidone (ZIP) is an effective antipsychotic with low side effects than other second-generation antipsychotics. Despite this, there are reports of adverse events and previous studies associating the use of ZIP the inflammatory response. It is possible to infer that bioactive molecules present in some foods could attenuate peripheral inflammatory and oxidative stress potentially triggered ZIP. Read More

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December 2018

A rare presentation of appendicitis inside the femoral canal: case report and literature review.

Surg Case Rep 2018 Dec 13;4(1):143. Epub 2018 Dec 13.

Department of General surgery, Redcliffe Hospital, Redcliffe, QLD, 4020, Australia.

Background: Femoral hernia accounts for 3% of all the hernias, and in 0.5-5% of cases, the appendix can migrate through the femoral hernia and is called de Garengeot hernia. It is a very rare condition, and the incidence of appendicitis in this type of hernia is as low as 0. Read More

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December 2018

Long-term outcome of a dilated cardiomyopathy patient after mitral valve surgery combined with tissue-engineered myoblast sheets-report of a case.

Surg Case Rep 2018 Dec 13;4(1):142. Epub 2018 Dec 13.

Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka, 565-0871, Japan.

Background: Dilated cardiomyopathy (DCM) is a life-threatening heart muscle disease characterized by progressive heart failure, which often requires left ventricular assist device (LVAD) implantation or heart transplantation (HTx). A tissue engineering strategy using cell sheets for end-stage heart failure has emerged in recent years.

Case Presentation: Here, we describe a 50-year-old DCM patient with severe symptoms of heart failure with severe mitral regurgitation (MR) who was not a candidate for LVAD or HTx. Read More

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December 2018

Giant gastrointestinal stromal tumor of the mediastinum associated with an esophageal hiatal hernia and chest discomfort: a case report.

Surg Case Rep 2018 Dec 13;4(1):144. Epub 2018 Dec 13.

Department of Surgery, Iwate Medical University School of Medicine, Iwate, Japan.

Background: Gastrointestinal stromal tumors (GISTs) grow relatively slowly and without specific symptoms; therefore, they are typically incidental findings. We report a rare gastric GIST in the mediastinum associated with chest discomfort and an esophageal hiatal hernia.

Case Presentation: An 81-year-old woman with chest discomfort was admitted to the hospital, where barium esophagography showed a sliding esophageal hiatal hernia and a tumor of the lower esophagus and gastric wall. Read More

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December 2018

Rare anatomic variation of the hepatic arterial blood supply: case report and literature review.

Surg Radiol Anat 2018 Dec 13. Epub 2018 Dec 13.

Department of General and Minimally Invasive Surgery, Centre Hospitalier de Luxembourg, 4, rue Ernest Barblé, 1210, Luxembourg City, Luxembourg.

Purpose: Our aim is to present a rare case of anatomic variation of the arterial blood supply to the liver because preoperative knowledge of hepatic vascular variations is mandatory in hepatic surgery and liver transplantation.

Methods: We present a case of unusual arterial blood supply to the liver, a right hepatic artery coming from the splenic artery, associated to a classical common hepatic artery and a left hepatic artery from the left gastric artery. Preoperative diagnosis was made using CT-scan and 3D reconstruction. Read More

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December 2018

Hepatic steatosis and reduction in steatosis following bariatric weight loss surgery differs between segments and lobes.

Eur Radiol 2018 Dec 13. Epub 2018 Dec 13.

Liver Imaging Group, Department of Radiology, University of California San Diego, 200 W. Arbor Drive #8756, San Diego, CA, 92103-8756, USA.

Objectives: The purpose of this study was to (1) evaluate proton density fat fraction (PDFF) distribution across liver segments at baseline and (2) compare longitudinal segmental PDFF changes across time points in adult patients undergoing a very low-calorie diet (VLCD) and subsequent bariatric weight loss surgery (WLS).

Methods: We performed a secondary analysis of data from 118 morbidly obese adult patients enrolled in a VLCD-WLS program. PDFF was estimated using magnitude-based confounder-corrected chemical-shift-encoded (CSE) MRI in each hepatic segment and lobe at baseline (visit 1), after completion of VLCD (visit 2), and at 1, 3, and 6 months (visits 3-5) following WLS. Read More

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December 2018

Decrease in interpretation time for both novice and experienced readers using a concurrent computer-aided detection system for digital breast tomosynthesis.

Eur Radiol 2018 Dec 13. Epub 2018 Dec 13.

Advanced Medical Device Research Division, Korea Electrotechnology Research Institute, 111 Hanggaul-ro, Sangnok-gu, Ansan-si, Gyeonggi-do, 15588, Republic of Korea.

Objectives: To compare the diagnostic performance and interpretation time of digital breast tomosynthesis (DBT) for both novice and experienced readers with and without using a computer-aided detection (CAD) system for concurrent read.

Methods: CAD system was developed for concurrent read in DBT interpretation. In this observer performance study, we used an enriched sample of 100 DBT cases including 70 with and 30 without breast cancers. Read More

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December 2018

Modifiable Risk-factors for Keratinocyte Cancers in Australia: A Case-control Study.

Acta Derm Venereol 2018 Dec 13. Epub 2018 Dec 13.

Department of Clinical Epidemiology and Applied Biostatistics, University Hospital Tübingen, DE-72076 Tübingen, Germany.

Keratinocyte cancer (KC) is the most common malignancy in Caucasians. The incidence of KC has increased over the past 40 years. This case-control study investigated the environmental and host risk-factors responsible for development of KC in Australia's high-risk population. Read More

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December 2018

Neptunium(iv)-hydroxamate complexes: their speciation, and kinetics and mechanism of hydrolysis.

Dalton Trans 2018 Dec 14. Epub 2018 Dec 14.

National Nuclear Laboratory, Central Laboratory, Sellafield, Cumbria CA20 1PG, UK.

Simple hydroxamic acids such as acteohydroxamic acid (AHA) have been identified as suitable reagents for the control of Pu and Np in advanced separation processes for nuclear fuel reprocessing such as the Advanced PUREX or UREX based recycle processes, due to their ability to strip the tetravalent form of Pu and Np from tri-butyl phosphate into nitric acid. However, both free and metal bound hydroxamates are known to undergo acid catalysed hydrolysis at low pH, the kinetics of which must be characterised before implementation of PUREX/UREX based reprocessing flowsheets. In support of this implementation, a comprehensive thermodynamic and kinetic model that describes both the complex speciation and hydrolysis of AHA in the presence of Np(iv) has been developed. Read More

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December 2018

Aortic treatment of native infection by reconstruction with the Omniflow II biologic prosthesis.

J Vasc Surg Cases Innov Tech 2018 Dec 4;4(4):296-300. Epub 2018 Dec 4.

Department of Thoracic and Cardiovascular Surgery, Trousseau University Hospital, Tours, France.

Aortic infection is a challenging condition. Fortunately, surgical revision of infected aorta with in situ reconstruction can provide long-term cure. The material for aortic repair remains an area of debate. Read More

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December 2018

Aneurysmal degeneration and rupture of deep vein conduit with formation of an arterial-vaginal fistula 13 years after creation of a femoral-femoral bypass.

J Vasc Surg Cases Innov Tech 2018 Dec 4;4(4):287-291. Epub 2018 Dec 4.

Department of Surgery, UT Southwestern Medical Center, Dallas, Tex.

The autologous deep vein is a suitable alternative to prosthetic or cadaveric grafts as a bypass conduit because of its superior durability and lower risk of complications. Aneurysmal degeneration of deep vein grafts is rarely seen but can potentially be fatal when it does occur. We describe the case of an 87-year-old woman who presented with acute vaginal bleeding due to the rupture of an aneurysmal femorofemoral bypass vein graft into the vagina. Read More

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December 2018

Minimally invasive treatment of vascular complications after neoaortoiliac system reconstruction using autologous vein grafts.

J Vasc Surg Cases Innov Tech 2018 Dec 4;4(4):283-286. Epub 2018 Dec 4.

Department of Vascular Surgery, Leiden University Medical Center, Leiden, the Netherlands.

Treatment of complications after neoaortoiliac system vein reconstruction is a complex clinical problem with poor results. Endovascular treatment might offer an acceptable outcome in selected cases. We report two rare complications after neoaortoiliac system vein reconstruction for an infected aortic graft. Read More

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December 2018

Aortic endograft explantation in the setting of prior heterotopic renal allograft.

J Vasc Surg Cases Innov Tech 2018 Dec 4;4(4):275-277. Epub 2018 Dec 4.

Division of Vascular Surgery, University of Rochester, Rochester, NY.

It is rare to require explantation of an aortic endograft placed for endovascular aneurysm repair (EVAR). Sustained aneurysm growth in the setting of prior endovascular repair, despite secondary interventions and use of adjuncts, is the most common cause of EVAR explantation. An infected endograft and aneurysm rupture after EVAR represent more urgent or emergent indications for explantation and have a significantly greater associated morbidity and mortality. Read More

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December 2018

Paraplegia after coronary artery bypass surgery: An uncommon complication in a patient with history of thoracic endovascular aortic repair.

J Vasc Surg Cases Innov Tech 2018 Dec 4;4(4):272-274. Epub 2018 Dec 4.

Cardiac Surgery, Marie Lannelongue Hospital, University of Paris Sud, Le Plessis-Robinson, France.

Neurologic lesions are unusual complications after coronary artery bypass surgery. Among them, paraplegia is one of the rarest, with only a few cases reported in the literature. We report a case of paraplegia after coronary artery bypass following previous thoracic endovascular aortic repair. Read More

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December 2018

Microendoscopic discectomy (MED) for lumbar disc herniation: comparison of learning curve of the surgery and outcome with other established case studies.

J Spine Surg 2018 Sep;4(3):630-637

Global Health City, Chennai, Tamil Nadu, India.

Background: To compare the results of a series of microendoscopic discectomies done at a government medical college in South India, with other published series and to analyze the learning curve for the procedure.

Methods: Microendoscopic discectomy (MED) was performed in 40 patients. The cases were in the age group between 20-50 years (mean age, 32. Read More

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September 2018

Extreme lateral lumbar interbody fusion (XLIF) in the management of degenerative scoliosis: a retrospective case series.

J Spine Surg 2018 Sep;4(3):610-615

Department of Neurosurgery, School of Medicine, University of Thessaly, Larissa, Greece.

Background: Surgical treatment of adult degenerative scoliosis (DS) always remains a challenge and often necessitates complex multilevel surgery via traditional open approaches. However, the severity of the procedure, in association with the fact that many of these patients are at an advanced age with several comorbidities, results in high rate of complications. Therefore, during the last decade, minimally invasive procedures have gained a place in the treatment of this pathology. Read More

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September 2018

Prophylactic muscle flap reconstruction after complex spine surgery for degenerative disease: case series and institutional protocol.

J Spine Surg 2018 Sep;4(3):560-567

Department of Orthopaedics, The Ohio State University Wexner Medical Center, Columbus, OH, USA.

Background: Wound complications can occur in up to 20% of patients following multilevel posterior spinal fusion. Currently, the use of local flaps has been reported in high-risk patients with a history of spinal neoplasm, radiation therapy, exposed hardware, multiple spine surgeries, or wound infections. However, there are no reports of prophylactic muscle flap wound closure in patients undergoing multi-level spinal fusion for degenerative pathology. Read More

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September 2018

Presence of both anti-contactin 1 and anti-neurofascin 140 antibodies in a case of chronic inflammatory demyelinating polyneuropathy.

eNeurologicalSci 2018 Dec 22;13:38-39. Epub 2018 Nov 22.

Department of Neurology, University of Florida, Gainesville, FL 32610, United States.

Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired disorder of peripheral nerves and nerve roots. Its cause is unknown, but recently antibodies to nodal and paranodal proteins have been discovered in a small subset of CIDP patients. These contactin and neurofascin-related immune-mediated neuropathies are thought to be variants of CIDP and often respond suboptimally to standard therapy. Read More

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December 2018

Jacobian-Based Task-Space Motion Planning for MRI-Actuated Continuum Robots.

IEEE Robot Autom Lett 2019 Jan 19;4(1):145-152. Epub 2018 Nov 19.

Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH.

Robot-assisted medical interventions, such as robotic catheter ablation, often require the robot to perform tasks on a tissue surface. This paper presents a task-space motion planning method that generates actuation trajectories which steer the end- effector of the MRI-actuated robot along desired trajectories on the surface. The continuum robot is modeled using the pseudo-rigid-body model, where the continuum body of the robot is approximated by rigid links joined by flexible joints. Read More

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January 2019

Post-traumatic pseudoaneurysms of the left gastric artery: A case report.

Trauma Case Rep 2019 Feb 5;19:1-6. Epub 2018 Dec 5.

Department of General Surgery, Division of Trauma Surgery, Eulji University Hostpital, Daejeon, Republic of Korea.

Post-traumatic pseudoaneurysm of the gastric artery is very rare. Prompt diagnosis and management are necessary because mortality is high due to massive intra-abdominal hemorrhage. A 79-year-old man complained of abdominal pain after slipping down 2 days prior to admission. Read More

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February 2019

Tumor of follicular infundibulum-associated neoplasms.

JAAD Case Rep 2019 Jan 4;5(1):15-18. Epub 2018 Dec 4.

Department Of Dermatology, Penn State Milton S. Hershey Medical Center.

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January 2019

Foreign Body Reaction Associated With Artificial LARS Ligaments: A Retrieval Study.

Orthop J Sports Med 2018 Dec 4;6(12):2325967118811604. Epub 2018 Dec 4.

St John of God Hospital, Subiaco, Perth, Australia.

Background: Artificial ligaments have been developed and used in the treatment of ligamentous injuries since the 1970s. The early generation of artificial ligaments showed promising short-term results but resulted in high rates of rupture and inflammatory reaction in the surrounding tissues.

Purpose: To determine whether the use of Ligament Augmentation and Reconstruction System (LARS) ligaments is associated with the development of intra-articular foreign body reaction. Read More

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December 2018

Axillary Nerve Position in Humeral Avulsions of the Glenohumeral Ligament.

Orthop J Sports Med 2018 Dec 5;6(12):2325967118811044. Epub 2018 Dec 5.

Department of Mathematics and Statistics, Faculty of Science and Engineering, Macquarie University, Sydney, Australia.

Background: The axillary nerve is at risk during repair of a humeral avulsion of the glenohumeral ligament (HAGL).

Purpose: To measure the distance between the axillary nerve and the free edge of a HAGL lesion on preoperative magnetic resonance imaging (MRI) and compare these findings to the actual intraoperative distance measured during open HAGL repair.

Study Design: Case series; Level of evidence, 4. Read More

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December 2018

Similarities and Differences Between Staphylococcal and Streptococcal Toxic Shock Syndromes in Children: Results From a 30-Case Cohort.

Front Pediatr 2018 28;6:360. Epub 2018 Nov 28.

Centre National de Référence des Staphylocoques, Institut des Agents Infectieux, Centre de Biologie et de Pathologie Nord, Hospices Civils de Lyon, Lyon, France.

Toxic shock syndromes (TSS) are severe shocks due to staphylococcal or streptococcal infection that require specific treatments. The early recognition of these shocks is crucial to improve their outcomes. The primary objective of this study was to compare characteristics and outcomes of staphylococcal and streptococcal TSS in children, in order to identify putative early clinical diagnostic criteria. Read More

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November 2018

Orthodontic-surgical management of an unusual dilacerated maxillary incisor.

J Orthod Sci 2018 15;7:24. Epub 2018 Nov 15.

Department of Orthodontics, National Dental Centre Singapore, 5 Second Hospital Avenue, Singapore 168938.

Orthodontic traction of an impacted dilacerated maxillary central incisor is clinically challenging and often results in a long treatment duration. A case of an unusual dilacerated central incisor with a 90° crown-root angulation and palatally displaced crown is presented herein. Using a single stage open window exposure of the crown on the palatal aspect with light orthodontic traction force, the impacted dilacerated central incisor crown was successfully positioned in alignment with the contralateral incisor. Read More

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November 2018

A Systematic Review of Atypical Teratoid Rhabdoid Tumor in Adults.

Front Oncol 2018 28;8:567. Epub 2018 Nov 28.

Division of Neuropathology, University of Alberta Hospital, Edmonton, AB, Canada.

Atypical teratoid/rhabdoid tumor in adults is a relatively rare malignant neoplasm. It is characterized by the presence of rhabdoid cells in combination with loss of either the INI1 or BRG1protein from the tumor cells. A systematic review was conducted using MEDLINE using the terms "atypical teratoid rhabdoid tumor" AND "adult. Read More

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November 2018
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