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    507 results match your criteria Case reports in dermatology[Journal]

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    A Case of Ceftriaxone-Induced Acute Generalized Exanthematous Pustulosis/Generalized Pustular Psoriasis Overlap.
    Case Rep Dermatol 2018 Jan-Apr;10(1):69-75. Epub 2018 Mar 27.
    Department of Dermatology, Shanghai Skin Disease Hospital, Shanghai, China.
    Acute generalized exanthematous pustulosis, characterized by subcorneal or superficial intraepidermal pustules, is induced by drugs in more than 90% of cases. Psoriasis is an autoimmune disease triggered by different conditions in genetically susceptible people. Generalized pustular psoriasis is an acute and severe clinical form of psoriasis, which usually occurs in patients with psoriasis undergoing aggravating factors. Read More

    Incidental Squamous Cell Carcinoma in an Epidermal Inclusion Cyst: A Case Report and Review of the Literature.
    Case Rep Dermatol 2018 Jan-Apr;10(1):61-68. Epub 2018 Mar 22.
    Department of Otolaryngology - Head and Neck Surgery, Loma Linda University, Loma Linda, California, USA.
    Epidermal inclusion cysts are common lesions that rarely develop into squamous cell carcinoma (SCC). Neoplastic change in these cysts can be associated with prominent symptoms such as pain, rapid growth, or ulceration. This study describes the case of a 64-year-old woman with a 4-year history of a largely asymptomatic neck mass, which after routine excision was found to be an epidermal inclusion cyst harboring well-differentiated SCC. Read More

    The Importance of Excluding Cutaneous T-Cell Lymphomas in Patients with a Working Diagnosis of Papuloerythroderma of Ofuji: A Case Series.
    Case Rep Dermatol 2018 Jan-Apr;10(1):46-54. Epub 2018 Feb 21.
    Division of Dermatology, University of Ottawa, Ottawa, Ontario, Canada.
    Papuloerythroderma of Ofuji (PEO) is an erythroderma-like eruption with flat-topped papules that spare the skin folds (a "deck-chair sign" finding). Many infections, medications, and systemic diseases have been associated with PEO, including cutaneous T-cell lymphomas (CTCL). The relationship between the clinical presentation of PEO and CTCL remains poorly elucidated. Read More

    A Case of Vulvar Schwannoma Mimicking Epidermoid Cyst.
    Case Rep Dermatol 2018 Jan-Apr;10(1):41-45. Epub 2018 Feb 15.
    Department of Medical Mycology, Shanghai Dermatology Hospital, Shanghai, China.
    Schwannoma is a generally benign tumor of the peripheral nerve sheath arising from Schwann cells. Most schwannomas are found on the head and neck. Here, we describe a rare case of benign vulvar schwannoma located at the labium majus which was similar to an epidermoid cyst in clinical appearance. Read More

    Extensive Lepromatous Lymphadenitis Preceding Lesions on the Face and Earlobes: An Unusual Presentation of Leprosy in Singapore.
    Case Rep Dermatol 2018 Jan-Apr;10(1):35-40. Epub 2018 Feb 14.
    Division of General Medicine, National University Health Systems, Singapore, Singapore.
    Leprosy is also known as Hansen disease, as in some countries the diagnosis of leprosy carries a negative stigma and patients fear being shunned as outcasts. Presently, leprosy is primarily limited to specific geographical regions in resource-poor countries. As a result, there is increased difficulty for the younger generation of physicians today to correctly identify leprosy due to a lack of exposure and a low-index of suspicion, particularly in developed countries. Read More

    Successful Treatment of Inflammatory Linear Verrucous Epidermal Nevus with Concomitant Psoriasis Using Etanercept.
    Case Rep Dermatol 2018 Jan-Apr;10(1):29-34. Epub 2018 Feb 14.
    Consultant Internist, Hera General Hospital, Makkah, Saudi Arabia.
    Linear psoriasis is a rare form of the disease characterized by the linear distribution of lesions involving dermatome or along Blaschko's lines. Clinically, it may resemble inflammatory linear verrucous epidermal nevus; a combination of history, skin examination, and histopathology are required to ensure correct diagnosis and appropriate therapy. This paper describes a case of a 23-year-old male presenting with unilateral erythematous scaly plaques arranged in a linear path on the left leg. Read More

    Incidental Treatment of a Subclinical Chronic Tension-Type Headache by Cosmetic Use of Botulinum Toxin A: A Case Report.
    Case Rep Dermatol 2017 Sep-Dec;9(3):249-253. Epub 2017 Nov 27.
    Department of Plastic and Breast Surgery, Zealand University Hospital, Roskilde, Denmark.
    Background: Headache is a common disorder of the nervous system; chronic headache in particular may affect quality of life negatively. The pathophysiology is multifactorial and not completely elucidated. Studies have demonstrated the beneficial effects of botulinum toxin A on chronic migraine headaches, but failed to show the same effect on chronic tension-type headaches. Read More

    Large-Cell Transformed Mycosis Fungoides Coexisting with Mycosis Fungoides Bullosa: A Case Report and Review of the Literature.
    Case Rep Dermatol 2017 Sep-Dec;9(3):243-248. Epub 2017 Nov 27.
    Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
    Mycosis fungoides is the most common form of cutaneous T-cell lymphoma. Both large-cell transformed mycosis fungoides and mycosis fungoides bullosa are rare presentations and predict unfavorable prognosis. We report the case of a 61-year-old woman who presented with generalized erythematous scaly annular plaques, and histopathology confirmed the diagnosis of mycosis fungoides. Read More

    Giant Congenital Melanocytic Nevi: An Update and Emerging Therapies.
    Case Rep Dermatol 2018 Jan-Apr;10(1):24-28. Epub 2018 Feb 8.
    cDepartment of Pediatrics, Richmond University Medical Center, New York, NY, USA.
    Giant congenital melanocytic nevi (GCMN) are a rare occurrence. Gain-of-function mutation in the NRAS gene is found to be associated with GCMN, causing abnormal proliferation of embryonic melanoblasts. The two major complications associated with GCMN are malignant melanoma and neurocutaneous melanosis. Read More

    Non-Melanoma Skin Cancers at Sites of Previous Frostbite: Case Report and Review.
    Case Rep Dermatol 2018 Jan-Apr;10(1):17-23. Epub 2018 Feb 1.
    bDepartment of Biomedical Sciences, Nazarbayev University School of Medicine, Astana, Kazakhstan.
    The association between ultraviolet radiation exposure and skin cancer is well established. Limited studies have reported an association between frostbite and the development of non-melanoma skin cancer but evidence for a proven link is insufficient and possible carcinogenic mechanisms have not been fully explored. In this report, 3 cases of non-melanoma skin cancer (1 case of basal cell carcinoma and 2 cases of squamous cell carcinoma of the skin) which developed at a site of previous frostbite caused by exposure to extremely cold temperatures in Astana, the capital city of Kazakhstan, are described. Read More

    Sarcomatoid Tumor following Radium Treatment.
    Case Rep Dermatol 2018 Jan-Apr;10(1):13-16. Epub 2018 Jan 31.
    aDepartment of Plastic and Breast Surgery, Zealand University Hospital, Roskilde, Denmark.
    Haemangiomas are benign skin lesions that usually regress spontaneously, but radiotherapy has previously been used to assist the regression and healing of the lesions. Radium and X-rays were used as a treatment for benign skin lesions such as haemangioma until the carcinogenic effect of ionising radiation in humans was described. We report a patient diagnosed with a sarcomatoid carcinoma. Read More

    Acute Erythroderma in a Patient Receiving TNF-α-Blocking Therapy for Hidradenitis Suppurativa.
    Case Rep Dermatol 2018 Jan-Apr;10(1):7-12. Epub 2018 Jan 31.
    Dermatology, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.
    Tumor necrosis factor-α (TNF-α) normally binds to TNF-α receptors, leading to the inflammatory response of autoimmune diseases. Adalimumab is a TNF-inhibiting, anti-inflammatory, biological medication which binds to TNF-α, thus reducing this inflammatory response. The use of TNF-α-inhibiting medication, such as adalimumab, being the first FDA-approved treatment for hidradenitis suppurativa, has drastically changed the management of dermatological diseases. Read More

    A Case of Erythema Multiforme Major Developed after Sequential Use of Two Immune Checkpoint Inhibitors, Nivolumab and Ipilimumab, for Advanced Melanoma: Possible Implication of Synergistic and/or Complementary Immunomodulatory Effects.
    Case Rep Dermatol 2018 Jan-Apr;10(1):1-6. Epub 2018 Jan 18.
    Department of Dermatology, Division of Medical Sciences, University of Fukui, Fukui, Japan.
    Immune checkpoint inhibitors, such as ipilimumab and nivolumab, reverse the imbalance of antitumor self-tolerance and enhance T-cell responses. Currently, ipilimumab and nivolumab have a reported therapeutic impact on unresectable or metastatic melanomas; however, they also induce immune-related adverse events (irAEs). Ipilimumab-induced cutaneous irAEs are mostly low grade and manageable, although all-grade rash may occur in approximately 45% of all patients. Read More

    Acrodermatitis Continua of Hallopeau with Bone Resorption in an 8-Year-Old Patient: A Case Report.
    Case Rep Dermatol 2017 Sep-Dec;9(3):259-264. Epub 2017 Dec 18.
    Department of Dermatology, King Saud University Medical City, Riyadh, Saudi Arabia.
    Acrodermatitis continua of Hallopeau (ACH) is an uncommon inflammatory disease manifesting as sterile pustular eruption of the fingers and toes. The disease is of a chronic relapsing nature and is often refractory to treatment. With longstanding disease, osteitis with consequent bone resorption of the underlying phalanges can occur, leading to disability. Read More

    Cutaneous Metastases from Salivary Duct Carcinoma of the Submandibular Gland.
    Case Rep Dermatol 2017 Sep-Dec;9(3):254-258. Epub 2017 Dec 5.
    Department of Plastic and Breast Surgery, Zealand University Hospital - Roskilde, Roskilde, Denmark.
    Salivary duct carcinoma is a rare and highly aggressive malignant neoplasm that frequently metastasises to other organs, but cutaneous metastasis is uncommon. There are only 6 cases reported in the literature with metastases to the skin and in all cases the tumour originates from the parotid gland. We present a case of skin metastases from the submandibular gland that was mistaken for basal cell carcinoma. Read More

    Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit.
    Case Rep Dermatol 2017 Sep-Dec;9(3):236-242. Epub 2017 Nov 14.
    Department of Rheumatology, Presence Saint Joseph Hospital, Chicago, Illinois, USA.
    A lichenoid drug eruption is a rare side effect which can occur following the administration of several different medications. Here we describe a unique case of fenofibrate as the causative agent of a lichenoid drug eruption. This case highlights a rare and clinically significant dermatologic side effect of fenofibrate. Read More

    Swan Neck Deformity Mimicking Claw Hand Caused by Arthritis in Leprosy.
    Case Rep Dermatol 2017 Sep-Dec;9(3):231-235. Epub 2017 Nov 14.
    Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Bandung, Indonesia.
    Swan neck deformity is a hyperextension of the proximal interphalangeal (PIP) joints and flexion of the distal interphalangeal (DIP) joints. Claw hand is a hyperextension of the metacarpal joints and flexion of the PIP joints, accompanied by reduced motor strength. A 23-year-old female, who was released from leprosy treatment, presented with a bend of the second to fifth fingers of both hands. Read More

    Carcinoma Cuniculatum of the Right Thenar Region with Bone Involvement and Lymph Node Metastases.
    Case Rep Dermatol 2017 Sep-Dec;9(3):225-230. Epub 2017 Nov 10.
    Department of Dermatology, Municipal Hospital Hietzing, Vienna, Austria.
    Squamous cell carcinoma (SCC) is the second most common type of skin cancer after basal cell carcinoma (BCC). The overall prevalence of BCC is 3 times higher than that of SCC, but this can vary when looking at specific locations such as the hand, where SCC is much more common than BCC. Carcinoma (or epithelioma) cuniculatum is a rare variant of SCC. Read More

    Lichen Planus Pemphigoides Induced by Enalapril: A Case Report and a Review of Literature.
    Case Rep Dermatol 2017 Sep-Dec;9(3):217-224. Epub 2017 Oct 31.
    Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
    Lichen planus pemphigoides (LPP) is a rare autoimmune bullous dermatosis. The clinical presentation of LPP may mimic bullous pemphigoid making the diagnosis difficult. A thorough clinical, histopathological, and immunological evaluation is essential for the diagnosis of LPP. Read More

    Treatment of Multiple Actinic Keratosis and Field of Cancerization with Topical Piroxicam 0.8% and Sunscreen 50+ in Organ Transplant Recipients: A Series of 10 Cases.
    Case Rep Dermatol 2017 Sep-Dec;9(3):211-216. Epub 2017 Oct 20.
    Department of Systems Medicine, Division of Dermatology, University of Rome Tor Vergata, Rome, Italy.
    Organ transplant recipient (OTR) subjects are at high risk of skin cancer such as squamous cell carcinoma and basal cell carcinoma. Actinic keratosis (AK) is considered the precursor of these non-melanoma skin cancers. Sun protection is mandatory in subjects with AK and this preventive strategy is very important in OTR. Read More

    CD30+ Cutaneous Anaplastic Large-Cell Lymphoma of the Upper Eyelid: A Case Report.
    Case Rep Dermatol 2017 Sep-Dec;9(3):206-210. Epub 2017 Oct 20.
    Department of Dermatology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.
    CD30+ cutaneous anaplastic large-cell lymphoma is part of the CD30+ T-cell lymphoproliferative disorders. This type of lymphoma is in most cases indolent, with a high survival rate. We report the case of a 59-year-old patient with a 1-month lasting crusty lesion of the upper eyelid. Read More

    Diffuse Dermal Angiomatosis of the Breast: A Distinct Entity in the Spectrum of Cutaneous Reactive Angiomatoses - Clinicopathologic Study of Two Cases and Comprehensive Review of the Literature.
    Case Rep Dermatol 2017 Sep-Dec;9(3):194-205. Epub 2017 Oct 13.
    Kempf und Pfaltz Histologische Diagnostik, Zurich, Switzerland.
    Diffuse dermal angiomatosis (DDA) is a rare reactive angioproliferation in the skin and considered to be a subtype in the group of cutaneous reactive angiomatoses. DDA is clinically characterized by livedoid patches and plaques with tender ulceration. Its histologic features are a reactive diffuse proliferation of bland endothelial cells and pericytes within the dermis, forming small capillary vessels. Read More

    Plaque-Type Syringoma: A Case Report.
    Case Rep Dermatol 2017 Sep-Dec;9(3):190-193. Epub 2017 Oct 4.
    Department of Dermatology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
    Syringomas are benign appendageal tumors originated from eccrine ducts. The lesions usually present as multiple small, firm papules at lower eyelids and cheeks of women. Plaque-type syringoma is an infrequent form of syringoma and to date, 12 cases have been reported. Read More

    Nevus Comedonicus: Case Report.
    Case Rep Dermatol 2017 Sep-Dec;9(3):184-189. Epub 2017 Oct 4.
    Sector of Dermatology and Post-Graduation Course, University Hospital and School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
    Nevus comedonicus is a rare cutaneous anomaly, characterized by the clustering of papules with firm, blackened horny buffers. It in general has a zosteriform pattern and affects both genders equally. In some patients, there is formation of cysts, abscesses, and fistulas, aggravating its psychosocial impact. Read More

    Looking Beyond the Cyclosporine "Swish and Spit" Technique in a Recalcitrant Case of Erosive Lichen Planus Involving the Tongue.
    Case Rep Dermatol 2017 Sep-Dec;9(3):177-183. Epub 2017 Oct 3.
    Postgraduate Institute of Medical Education and Research (PGIMER), Delhi, India.
    Oral lichen planus is a relatively common autoimmune disease affecting the middle-aged population. Although no treatment is necessary for a benign asymptomatic case, in case of erosive lichen planus, topical corticosteroids form the mainstay of treatment. In case of failure, apart from tacrolimus, cyclosporine, using the "swish and spit" technique, is a valid therapeutic intervention. Read More

    Successful Topical Treatment of Pigmented Purpuric Lichenoid Dermatitis of Gougerot-Blum in a Young Patient: A Case Report and Summary of the Most Common Pigmented Purpuric Dermatoses.
    Case Rep Dermatol 2017 Sep-Dec;9(3):169-176. Epub 2017 Sep 15.
    Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.
    We report the case of a 12-year-old girl who presented a rash with reddish-brown patches on the trunk and extremities indicative of pigmented purpuric lichenoid dermatitis of Gougerot-Blum (PPLD). The histological findings were characteristic for PPLD, thus supporting the diagnosis. Topically administered corticosteroid led to a fast resolution of all symptoms. Read More

    Facial Edema in an Elderly Man: An Unusual Presentation of Nonepisodic Angioedema with Eosinophilia.
    Case Rep Dermatol 2017 Sep-Dec;9(3):164-168. Epub 2017 Sep 12.
    Department of Dermatology, Yokohama City Minato Red Cross Hospital, Yokohama, Japan.
    Nonepisodic angioedema with eosinophilia (NEAE) is a rare allergic disease with a young Japanese and East Asian female predominance. NEAE features transient, nonrecurrent angioedema and peripheral blood eosinophilia without visceral organ involvement. Angioedema in NEAE occurs on the extremities, while the trunk and face are rarely involved. Read More

    Certolizumab Pegol-Induced Folliculitis-Like Lichenoid Sarcoidosis in a Patient with Rheumatoid Arthritis.
    Case Rep Dermatol 2017 Sep-Dec;9(3):158-163. Epub 2017 Sep 11.
    Department of Dermatology, Asahikawa City Hospital, Asahikawa, Japan.
    Anti-tumor necrosis factor α (TNF-α) biologic agents are used for treating refractory sarcoidosis. However, sarcoidosis-like epithelioid cell granulomas may develop during anti-TNF-α treatment. A 63-year-old man suffering from rheumatoid arthritis was treated with oral methotrexate and methylprednisolone for 4 years. Read More

    Pachyderma in Primary Cutaneous NK and T-Cell Lymphoma and Leukemia Cutis.
    Case Rep Dermatol 2017 Sep-Dec;9(3):151-157. Epub 2017 Sep 11.
    Department of Dermatology, Liège University Hospital, Liège, Belgium.
    Background: Pachyderma is defined as severely thickened skin with deep folds and is occasionally observed with primary cutaneous NK and T-cell lymphoma (pCNKTCL), primary cutaneous B-cell lymphoma (pCBCL), and leukemia cutis (LC).

    Aim: To describe the clinical, histological, and therapeutic particularities of a series of pCNKTCL, pCBCL, and LC patients with pachyderma.

    Results: In a series of pCNKTCL ( = 70), pCBCL ( = 12), and LC ( = 2) patients followed up during 9 years, 6 cases of pachyderma were observed. Read More

    An Unusual Presentation of Pyoderma Gangrenosum Leading to Systemic Inflammatory Response Syndrome.
    Case Rep Dermatol 2017 Sep-Dec;9(3):146-150. Epub 2017 Sep 11.
    Department of Dermatology, Fiona Stanley Hospital, Murdoch, Washington, Australia.
    This is a report of an atypical presentation of pyoderma gangrenosum (PG) in a 26-year-old male who had a negative septic screen. The patient had a life-threatening presentation requiring an intensive care unit (ICU) admission for vasopressor support. It was thought that the likely cause of circulatory collapse was an overwhelming cytokine reaction or systemic inflammatory response syndrome (SIRS) secondary to extensive PG lesions rather than septic shock. Read More

    Itolizumab - A New Biologic for Management of Psoriasis and Psoriatic Arthritis.
    Case Rep Dermatol 2017 May-Aug;9(2):141-145. Epub 2017 Aug 23.
    Derma-Care Skin and Cosmetology Centre, Mangalore, India.
    Psoriasis is a chronic, relapsing, inflammatory, immune-mediated systemic disease with mainly skin and joint manifestations. The available treatment options to cure psoriasis include topical therapy, phototherapy, and biological therapy. Biological therapy has become a promising option due to the rapid action and less adverse effects associated with its use. Read More

    Cholesterotic Fibrous Histiocytoma in a Patient with Metabolic Syndrome.
    Case Rep Dermatol 2017 May-Aug;9(2):136-140. Epub 2017 Aug 17.
    Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
    Among the many variants of dermatofibroma, dermatofibroma with cholesterol cleft (cholesterotic fibrous histiocytoma) is extremely rare. Here, we describe the case of a 50-year-old male patient with a cholesterotic fibrous histiocytoma on his left lower leg. He presented with a hyperkeratotic nodule 6 mm in diameter with a brown surface on the extensor surface of his left lower leg. Read More

    Verruciform Xanthoma of a Lower Lip Lesion: A New Case and Review of the Literature.
    Case Rep Dermatol 2017 May-Aug;9(2):130-135. Epub 2017 Aug 17.
    Department of Dermatology, Near East University Faculty of Medicine, Nicosia, Cyprus.
    A non-smoking man in his seventh decade presented with a lesion he had had for about 5 years on the right external surface of the lip 1 mm from the vermilion border. On physical examination, a yellowish-coloured, non-tender, verrucous mass of 0.5 × 0. Read More

    Cutaneous Nocardiosis Simulating Cutaneous Lymphatic Sporotrichosis.
    Case Rep Dermatol 2017 May-Aug;9(2):119-129. Epub 2017 Aug 17.
    Sector of Dermatology and Post-Graduation Course in Dermatology, University Hospital and School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
    Sporotrichosis is the subcutaneous mycosis caused by several species of the Sporothrix genus. With worldwide occurrence, the State of Rio de Janeiro is presently undergoing a zoonotic sporotrichosis epidemic. The form of lymphocutaneous nocardiosis is rare, being caused especially by It appears as a nodular or ulcerated lesion, with multiple painful erythematous nodules or satellite pustules distributed along the lymphatic tract, similar to the lymphocutaneous variant of sporotrichosis. Read More

    A Case of Aplasia Cutis Congenita Type VI: Bart Syndrome.
    Case Rep Dermatol 2017 May-Aug;9(2):112-118. Epub 2017 Aug 3.
    Dermatology Department, King Fahad Armed Force Hospital, Jeddah, Saudi Arabia.
    Aplasia cutis congenita type VI, also known as Bart syndrome, is a rare genetic mechanobullous disorder characterized by congenital localized absence of skin, mucocutaneous blistering lesions, and nail abnormalities. We present the case of a 4-h-old male newborn who presented with complete absence of skin over the anteromedial aspect of both lower legs associated with nail dystrophy since birth. After a few days, he developed blisters that were consistent with epidermolysis bullosa in histopathological examination. Read More

    Recurrence of Melanoma after Starting Apremilast for Psoriasis.
    Case Rep Dermatol 2017 May-Aug;9(2):108-111. Epub 2017 Aug 3.
    Division of Dermatology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
    This is a report on a 32-year-old man with a history of two previous melanomas with concurrent plaque-type psoriasis. His history dates to 2009, when he was diagnosed with his first melanoma on the right occiput, Clark's level IV, tumor thickness 1.53 mm, nonulcerated, mitotic index 1/mm. Read More

    The Successful Use of a Novel Microwave Device in the Treatment of a Plantar Wart.
    Case Rep Dermatol 2017 May-Aug;9(2):102-107. Epub 2017 Jul 27.
    Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
    Plantar warts, caused by the human papilloma virus (HPV), are a commonly encountered condition presenting in clinic. In adults, an array of various therapies exists, frequently with modest results particularly with plantar lesions. Microwaves have had limited uses for medical purposes. Read More

    Epidermolytic Acanthoma on Fingers, Mimicking Flat Warts.
    Case Rep Dermatol 2017 May-Aug;9(2):98-101. Epub 2017 Jul 14.
    Division of Dermatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
    Epidermolytic acanthoma (EA) is a benign cutaneous condition. It is characterized by warty or flat-topped, keratotic papules that show epidermolytic hyperkeratosis in histology. EA has been described to occur in various locations, namely the trunk, face, and genitoscrotal area. Read More

    The Use of Intralesional Steroids in a Case of Localized Pemphigus Foliaceus.
    Case Rep Dermatol 2017 May-Aug;9(2):91-97. Epub 2017 Jul 13.
    Department of Dermatology, Herbert Wertheim College of Medicine, Florida International University, Greater Miami Skin and Laser Center, Miami, Florida, USA.
    A 37-year-old South-Asian male presented to our clinic with a crusty, verrucous-like, scaly plaque of the left ala of the nose. After ruling out infectious and other epidermal bullous diseases, we finalized a diagnosis of localized pemphigus foliaceus, an exceptionally rare disorder with only 15 cases reported in the literature to date. The hyperkeratotic lesions responded favorably to a 3-week regimen of triamcinolone ointment and a onetime intralesional triamcinolone 2. Read More

    Sweet's Syndrome Arising in a Scar.
    Case Rep Dermatol 2017 May-Aug;9(2):86-90. Epub 2017 Jul 13.
    Tripler Army Medical Center, Honolulu, Hawaii, USA.
    Acute febrile neutrophilic dermatosis (Sweet's syndrome) is an uncommon inflammatory cutaneous disorder. It presents with lesions which are tender, erythematous, edematous papules and under histologic examination show dense neutrophilic infiltration of the dermis. These lesions are often accompanied by leukocytosis and fever. Read More

    Extrafacial Granuloma Faciale: A Case Report and Brief Review.
    Case Rep Dermatol 2017 May-Aug;9(2):79-85. Epub 2017 Jul 13.
    Department of Dermatology, Mater Misericordiae Hospital, Brisbane, Queensland, Australia.
    Granuloma faciale (GF) is a rare, inflammatory, cutaneous disorder of unknown aetiology. It presents clinically as one or several well-circumscribed violaceous papules, plaques, and nodules almost exclusively confined to the facial region. Rarely, extrafacial lesions can occur, most often on sun-exposed sites. Read More

    A Disease-Modifying Approach for Advanced Hidradenitis Suppurativa (Regimen with Metformin, Liraglutide, Dapsone, and Finasteride): A Case Report.
    Case Rep Dermatol 2017 May-Aug;9(2):70-78. Epub 2017 Jul 13.
    UNMC Department of Family Medicine, Nebraska Medical Center, Omaha, Nebraska, USA.
    Hidradenitis suppurativa (HS) is a challenging skin disease with limited therapeutic options. Obesity and metabolic syndrome are being increasingly implicated and associated with younger ages and greater metabolic severity. A 19-year-old female with an 8-year history of progressively debilitating cicatricial HS disease presented with obesity, profound anemia, leukocytosis, increased platelet count, hypoalbuminemia, and elevated liver enzymes. Read More

    Wells' Syndrome Successfully Treated with Colchicine.
    Case Rep Dermatol 2017 May-Aug;9(2):65-69. Epub 2017 Jul 13.
    Pathology Department, Complejo Hospitalario Universitario de Pontevedra, EOXI Pontevedra-Salnés, Pontevedra, Spain.
    Eosinophilic cellulitis is an uncommon, inflammatory and chronic disorder of unknown etiology. Corticosteroids are currently considered as the first-line treatment but they are not without significant disadvantages such as contraindications in steroid-resistant cases and patients with frequent recurrences. We report a patient suffering from Wells' syndrome with a 24-year history of symptomatic and generalized skin lesions. Read More

    Scabies Associated with Granulomatous Dermatitis.
    Case Rep Dermatol 2017 May-Aug;9(2):60-64. Epub 2017 Jul 13.
    Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida, USA.
    Scabies is a relatively common parasitic infection, which has sometimes been associated with the formation of granuloma annulare. We report the case of an 86-year-old female who developed a non-necrotizing granulomatous dermatitis after a scabies infestation. This case highlights the importance of considering scabies in the differential diagnosis when granulomatous dermatitis is noted histologically that cannot be explained by other causes. Read More

    Efficacy and Tolerability of Polyphenon E in "Difficult-to-Treat" Multiple Genital Warts in an HIV-Positive Male Subject.
    Case Rep Dermatol 2017 May-Aug;9(2):55-59. Epub 2017 Jun 27.
    Medical Department, Difa Cooper, Caronno, Italy.
    A 55-year-old man, nonsmoker, with a HIV-positive history came to our attention in February 2017. He was on treatment with Stribild, 1 capsule daily (150 mg elvitegravir, 150 mg cobicistat, 200 mg emtricitabine, and 245 mg tenofovir disoproxil). The CD4+/CD8+ cellular count was 326/µL (normal values: 404-1,612); the CD3+/CD8+ cellular count was 819/µL (normal values: 220-1,219). Read More

    Delayed Diagnosis of Basal Cell Carcinoma of the Upper Lip: The Possible Role of Incidental Multinucleated Foreign Body Giant Cells.
    Case Rep Dermatol 2017 May-Aug;9(2):50-54. Epub 2017 Jun 16.
    Department of Dermatology, University of Texas Medical Branch, Galveston, Texas, USA.
    Herpes simplex and basal cell carcinoma (BCC) can have similar clinical presentations due to overlapping lesional morphology. We describe the unusual case of a BCC masquerading as herpes labialis due to a possible false-positive Tzanck smear. The confounding diagnosis led to a failed trial of valacyclovir and subsequent loss of the patient for 1 year before the lesion was biopsied and diagnosed as a BCC. Read More

    Trichoscopic Findings of Erosive Pustular Dermatosis of the Scalp Associated with Gefitinib.
    Case Rep Dermatol 2017 May-Aug;9(2):44-49. Epub 2017 Jun 14.
    Department of Dermatology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
    Alopecia associated with epidermal growth factor receptor (EGFR) inhibitor therapy is a rare cutaneous side effect with the potential to progress to scarring alopecia. Thus, dermatologists should make an early diagnosis. We present the case of a 57-year-old Japanese female with scarring alopecia associated with gefitinib, which is an EGFR inhibitor, including trichoscopic findings. Read More

    Erythema Gyratum Repens-Like Purpura in a Patient with Sjögren Syndrome.
    Case Rep Dermatol 2017 May-Aug;9(2):40-43. Epub 2017 Jun 14.
    Department of Dermatology, Tokyo Medical University, Tokyo, Japan.
    The etiology of purpura in Sjögren syndrome (SS) includes cryoglobulinemia, hypergammaglobulinemia, and leukocytoclastic vasculitis (LCV). The clinical symptoms of LCV associated with SS comprise palpable or nonpalpable purpura and urticarial vasculitis. Here, we report a case of LCV presenting as erythema gyratum repens (EGR)-like purpura in a 62-year-old woman with rheumatoid arthritis and SS. Read More

    Eruptive Seborrheic Keratoses Restricted to Plaque/Patch-Stage Mycosis Fungoides.
    Case Rep Dermatol 2017 May-Aug;9(2):35-39. Epub 2017 Jun 8.
    Department of Dermatology, CHU Sart Tilman, University of Liège, Liège, Belgium.
    Eruptive seborrheic keratoses (ESK) are rare in dermatology. They are usually inflammatory in nature and may be encountered as Leser-Trélat sign. ESK may also be simultaneously observed with hepatic angiomas, chemotherapy, segmental neurofibromatosis, HIV or erythrodermic pityriasis rubra pilaris, psoriasis, and drug eruption. Read More

    A Case of Facial Partial Unilateral Lentiginosis Treated with Low-Fluence 1,064 nm Q-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser.
    Case Rep Dermatol 2017 May-Aug;9(2):30-34. Epub 2017 Jun 1.
    Department of Dermatology, Cheil General Hospital and Women's Healthcare Center, Dankook University College of Medicine, Cheonan, Republic of Korea.
    Partial unilateral lentiginosis (PUL) is an unusual pigmentary disorder characterized by numerous lentigines grouped within an area of normal skin. Although treatment is not necessary, many patients with facial PUL seek medical help for cosmetic reasons. There is no established standard treatment for PUL. Read More

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