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    485 results match your criteria Case reports in dermatology[Journal]

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    Plaque-Type Syringoma: A Case Report.
    Case Rep Dermatol 2017 Sep-Dec;9(3):190-193. Epub 2017 Oct 4.
    Department of Dermatology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
    Syringomas are benign appendageal tumors originated from eccrine ducts. The lesions usually present as multiple small, firm papules at lower eyelids and cheeks of women. Plaque-type syringoma is an infrequent form of syringoma and to date, 12 cases have been reported. Read More

    Nevus Comedonicus: Case Report.
    Case Rep Dermatol 2017 Sep-Dec;9(3):184-189. Epub 2017 Oct 4.
    Sector of Dermatology and Post-Graduation Course, University Hospital and School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
    Nevus comedonicus is a rare cutaneous anomaly, characterized by the clustering of papules with firm, blackened horny buffers. It in general has a zosteriform pattern and affects both genders equally. In some patients, there is formation of cysts, abscesses, and fistulas, aggravating its psychosocial impact. Read More

    Looking Beyond the Cyclosporine "Swish and Spit" Technique in a Recalcitrant Case of Erosive Lichen Planus Involving the Tongue.
    Case Rep Dermatol 2017 Sep-Dec;9(3):177-183. Epub 2017 Oct 3.
    Postgraduate Institute of Medical Education and Research (PGIMER), Delhi, India.
    Oral lichen planus is a relatively common autoimmune disease affecting the middle-aged population. Although no treatment is necessary for a benign asymptomatic case, in case of erosive lichen planus, topical corticosteroids form the mainstay of treatment. In case of failure, apart from tacrolimus, cyclosporine, using the "swish and spit" technique, is a valid therapeutic intervention. Read More

    Successful Topical Treatment of Pigmented Purpuric Lichenoid Dermatitis of Gougerot-Blum in a Young Patient: A Case Report and Summary of the Most Common Pigmented Purpuric Dermatoses.
    Case Rep Dermatol 2017 Sep-Dec;9(3):169-176. Epub 2017 Sep 15.
    Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.
    We report the case of a 12-year-old girl who presented a rash with reddish-brown patches on the trunk and extremities indicative of pigmented purpuric lichenoid dermatitis of Gougerot-Blum (PPLD). The histological findings were characteristic for PPLD, thus supporting the diagnosis. Topically administered corticosteroid led to a fast resolution of all symptoms. Read More

    Facial Edema in an Elderly Man: An Unusual Presentation of Nonepisodic Angioedema with Eosinophilia.
    Case Rep Dermatol 2017 Sep-Dec;9(3):164-168. Epub 2017 Sep 12.
    Department of Dermatology, Yokohama City Minato Red Cross Hospital, Yokohama, Japan.
    Nonepisodic angioedema with eosinophilia (NEAE) is a rare allergic disease with a young Japanese and East Asian female predominance. NEAE features transient, nonrecurrent angioedema and peripheral blood eosinophilia without visceral organ involvement. Angioedema in NEAE occurs on the extremities, while the trunk and face are rarely involved. Read More

    Certolizumab Pegol-Induced Folliculitis-Like Lichenoid Sarcoidosis in a Patient with Rheumatoid Arthritis.
    Case Rep Dermatol 2017 Sep-Dec;9(3):158-163. Epub 2017 Sep 11.
    Department of Dermatology, Asahikawa City Hospital, Asahikawa, Japan.
    Anti-tumor necrosis factor α (TNF-α) biologic agents are used for treating refractory sarcoidosis. However, sarcoidosis-like epithelioid cell granulomas may develop during anti-TNF-α treatment. A 63-year-old man suffering from rheumatoid arthritis was treated with oral methotrexate and methylprednisolone for 4 years. Read More

    Pachyderma in Primary Cutaneous NK and T-Cell Lymphoma and Leukemia Cutis.
    Case Rep Dermatol 2017 Sep-Dec;9(3):151-157. Epub 2017 Sep 11.
    Department of Dermatology, Liège University Hospital, Liège, Belgium.
    Background: Pachyderma is defined as severely thickened skin with deep folds and is occasionally observed with primary cutaneous NK and T-cell lymphoma (pCNKTCL), primary cutaneous B-cell lymphoma (pCBCL), and leukemia cutis (LC).

    Aim: To describe the clinical, histological, and therapeutic particularities of a series of pCNKTCL, pCBCL, and LC patients with pachyderma.

    Results: In a series of pCNKTCL (n = 70), pCBCL (n = 12), and LC (n = 2) patients followed up during 9 years, 6 cases of pachyderma were observed. Read More

    An Unusual Presentation of Pyoderma Gangrenosum Leading to Systemic Inflammatory Response Syndrome.
    Case Rep Dermatol 2017 Sep-Dec;9(3):146-150. Epub 2017 Sep 11.
    Department of Dermatology, Fiona Stanley Hospital, Murdoch, Washington, Australia.
    This is a report of an atypical presentation of pyoderma gangrenosum (PG) in a 26-year-old male who had a negative septic screen. The patient had a life-threatening presentation requiring an intensive care unit (ICU) admission for vasopressor support. It was thought that the likely cause of circulatory collapse was an overwhelming cytokine reaction or systemic inflammatory response syndrome (SIRS) secondary to extensive PG lesions rather than septic shock. Read More

    Itolizumab - A New Biologic for Management of Psoriasis and Psoriatic Arthritis.
    Case Rep Dermatol 2017 May-Aug;9(2):141-145. Epub 2017 Aug 23.
    Derma-Care Skin and Cosmetology Centre, Mangalore, India.
    Psoriasis is a chronic, relapsing, inflammatory, immune-mediated systemic disease with mainly skin and joint manifestations. The available treatment options to cure psoriasis include topical therapy, phototherapy, and biological therapy. Biological therapy has become a promising option due to the rapid action and less adverse effects associated with its use. Read More

    Cholesterotic Fibrous Histiocytoma in a Patient with Metabolic Syndrome.
    Case Rep Dermatol 2017 May-Aug;9(2):136-140. Epub 2017 Aug 17.
    Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
    Among the many variants of dermatofibroma, dermatofibroma with cholesterol cleft (cholesterotic fibrous histiocytoma) is extremely rare. Here, we describe the case of a 50-year-old male patient with a cholesterotic fibrous histiocytoma on his left lower leg. He presented with a hyperkeratotic nodule 6 mm in diameter with a brown surface on the extensor surface of his left lower leg. Read More

    Verruciform Xanthoma of a Lower Lip Lesion: A New Case and Review of the Literature.
    Case Rep Dermatol 2017 May-Aug;9(2):130-135. Epub 2017 Aug 17.
    Department of Dermatology, Near East University Faculty of Medicine, Nicosia, Cyprus.
    A non-smoking man in his seventh decade presented with a lesion he had had for about 5 years on the right external surface of the lip 1 mm from the vermilion border. On physical examination, a yellowish-coloured, non-tender, verrucous mass of 0.5 × 0. Read More

    Cutaneous Nocardiosis Simulating Cutaneous Lymphatic Sporotrichosis.
    Case Rep Dermatol 2017 May-Aug;9(2):119-129. Epub 2017 Aug 17.
    Sector of Dermatology and Post-Graduation Course in Dermatology, University Hospital and School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
    Sporotrichosis is the subcutaneous mycosis caused by several species of the Sporothrix genus. With worldwide occurrence, the State of Rio de Janeiro is presently undergoing a zoonotic sporotrichosis epidemic. The form of lymphocutaneous nocardiosis is rare, being caused especially by Nocardia brasiliensis. Read More

    A Case of Aplasia Cutis Congenita Type VI: Bart Syndrome.
    Case Rep Dermatol 2017 May-Aug;9(2):112-118. Epub 2017 Aug 3.
    Dermatology Department, King Fahad Armed Force Hospital, Jeddah, Saudi Arabia.
    Aplasia cutis congenita type VI, also known as Bart syndrome, is a rare genetic mechanobullous disorder characterized by congenital localized absence of skin, mucocutaneous blistering lesions, and nail abnormalities. We present the case of a 4-h-old male newborn who presented with complete absence of skin over the anteromedial aspect of both lower legs associated with nail dystrophy since birth. After a few days, he developed blisters that were consistent with epidermolysis bullosa in histopathological examination. Read More

    Recurrence of Melanoma after Starting Apremilast for Psoriasis.
    Case Rep Dermatol 2017 May-Aug;9(2):108-111. Epub 2017 Aug 3.
    Division of Dermatology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
    This is a report on a 32-year-old man with a history of two previous melanomas with concurrent plaque-type psoriasis. His history dates to 2009, when he was diagnosed with his first melanoma on the right occiput, Clark's level IV, tumor thickness 1.53 mm, nonulcerated, mitotic index 1/mm(2). Read More

    The Successful Use of a Novel Microwave Device in the Treatment of a Plantar Wart.
    Case Rep Dermatol 2017 May-Aug;9(2):102-107. Epub 2017 Jul 27.
    Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
    Plantar warts, caused by the human papilloma virus (HPV), are a commonly encountered condition presenting in clinic. In adults, an array of various therapies exists, frequently with modest results particularly with plantar lesions. Microwaves have had limited uses for medical purposes. Read More

    Epidermolytic Acanthoma on Fingers, Mimicking Flat Warts.
    Case Rep Dermatol 2017 May-Aug;9(2):98-101. Epub 2017 Jul 14.
    Division of Dermatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
    Epidermolytic acanthoma (EA) is a benign cutaneous condition. It is characterized by warty or flat-topped, keratotic papules that show epidermolytic hyperkeratosis in histology. EA has been described to occur in various locations, namely the trunk, face, and genitoscrotal area. Read More

    The Use of Intralesional Steroids in a Case of Localized Pemphigus Foliaceus.
    Case Rep Dermatol 2017 May-Aug;9(2):91-97. Epub 2017 Jul 13.
    Department of Dermatology, Herbert Wertheim College of Medicine, Florida International University, Greater Miami Skin and Laser Center, Miami, Florida, USA.
    A 37-year-old South-Asian male presented to our clinic with a crusty, verrucous-like, scaly plaque of the left ala of the nose. After ruling out infectious and other epidermal bullous diseases, we finalized a diagnosis of localized pemphigus foliaceus, an exceptionally rare disorder with only 15 cases reported in the literature to date. The hyperkeratotic lesions responded favorably to a 3-week regimen of triamcinolone ointment and a onetime intralesional triamcinolone 2. Read More

    Sweet's Syndrome Arising in a Scar.
    Case Rep Dermatol 2017 May-Aug;9(2):86-90. Epub 2017 Jul 13.
    Tripler Army Medical Center, Honolulu, Hawaii, USA.
    Acute febrile neutrophilic dermatosis (Sweet's syndrome) is an uncommon inflammatory cutaneous disorder. It presents with lesions which are tender, erythematous, edematous papules and under histologic examination show dense neutrophilic infiltration of the dermis. These lesions are often accompanied by leukocytosis and fever. Read More

    Extrafacial Granuloma Faciale: A Case Report and Brief Review.
    Case Rep Dermatol 2017 May-Aug;9(2):79-85. Epub 2017 Jul 13.
    Department of Dermatology, Mater Misericordiae Hospital, Brisbane, Queensland, Australia.
    Granuloma faciale (GF) is a rare, inflammatory, cutaneous disorder of unknown aetiology. It presents clinically as one or several well-circumscribed violaceous papules, plaques, and nodules almost exclusively confined to the facial region. Rarely, extrafacial lesions can occur, most often on sun-exposed sites. Read More

    A Disease-Modifying Approach for Advanced Hidradenitis Suppurativa (Regimen with Metformin, Liraglutide, Dapsone, and Finasteride): A Case Report.
    Case Rep Dermatol 2017 May-Aug;9(2):70-78. Epub 2017 Jul 13.
    UNMC Department of Family Medicine, Nebraska Medical Center, Omaha, Nebraska, USA.
    Hidradenitis suppurativa (HS) is a challenging skin disease with limited therapeutic options. Obesity and metabolic syndrome are being increasingly implicated and associated with younger ages and greater metabolic severity. A 19-year-old female with an 8-year history of progressively debilitating cicatricial HS disease presented with obesity, profound anemia, leukocytosis, increased platelet count, hypoalbuminemia, and elevated liver enzymes. Read More

    Wells' Syndrome Successfully Treated with Colchicine.
    Case Rep Dermatol 2017 May-Aug;9(2):65-69. Epub 2017 Jul 13.
    Pathology Department, Complejo Hospitalario Universitario de Pontevedra, EOXI Pontevedra-Salnés, Pontevedra, Spain.
    Eosinophilic cellulitis is an uncommon, inflammatory and chronic disorder of unknown etiology. Corticosteroids are currently considered as the first-line treatment but they are not without significant disadvantages such as contraindications in steroid-resistant cases and patients with frequent recurrences. We report a patient suffering from Wells' syndrome with a 24-year history of symptomatic and generalized skin lesions. Read More

    Scabies Associated with Granulomatous Dermatitis.
    Case Rep Dermatol 2017 May-Aug;9(2):60-64. Epub 2017 Jul 13.
    Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida, USA.
    Scabies is a relatively common parasitic infection, which has sometimes been associated with the formation of granuloma annulare. We report the case of an 86-year-old female who developed a non-necrotizing granulomatous dermatitis after a scabies infestation. This case highlights the importance of considering scabies in the differential diagnosis when granulomatous dermatitis is noted histologically that cannot be explained by other causes. Read More

    Efficacy and Tolerability of Polyphenon E in "Difficult-to-Treat" Multiple Genital Warts in an HIV-Positive Male Subject.
    Case Rep Dermatol 2017 May-Aug;9(2):55-59. Epub 2017 Jun 27.
    Medical Department, Difa Cooper, Caronno, Italy.
    A 55-year-old man, nonsmoker, with a HIV-positive history came to our attention in February 2017. He was on treatment with Stribild(TM), 1 capsule daily (150 mg elvitegravir, 150 mg cobicistat, 200 mg emtricitabine, and 245 mg tenofovir disoproxil). The CD4+/CD8+ cellular count was 326/µL (normal values: 404-1,612); the CD3+/CD8+ cellular count was 819/µL (normal values: 220-1,219). Read More

    Delayed Diagnosis of Basal Cell Carcinoma of the Upper Lip: The Possible Role of Incidental Multinucleated Foreign Body Giant Cells.
    Case Rep Dermatol 2017 May-Aug;9(2):50-54. Epub 2017 Jun 16.
    Department of Dermatology, University of Texas Medical Branch, Galveston, Texas, USA.
    Herpes simplex and basal cell carcinoma (BCC) can have similar clinical presentations due to overlapping lesional morphology. We describe the unusual case of a BCC masquerading as herpes labialis due to a possible false-positive Tzanck smear. The confounding diagnosis led to a failed trial of valacyclovir and subsequent loss of the patient for 1 year before the lesion was biopsied and diagnosed as a BCC. Read More

    Trichoscopic Findings of Erosive Pustular Dermatosis of the Scalp Associated with Gefitinib.
    Case Rep Dermatol 2017 May-Aug;9(2):44-49. Epub 2017 Jun 14.
    Department of Dermatology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
    Alopecia associated with epidermal growth factor receptor (EGFR) inhibitor therapy is a rare cutaneous side effect with the potential to progress to scarring alopecia. Thus, dermatologists should make an early diagnosis. We present the case of a 57-year-old Japanese female with scarring alopecia associated with gefitinib, which is an EGFR inhibitor, including trichoscopic findings. Read More

    Erythema Gyratum Repens-Like Purpura in a Patient with Sjögren Syndrome.
    Case Rep Dermatol 2017 May-Aug;9(2):40-43. Epub 2017 Jun 14.
    Department of Dermatology, Tokyo Medical University, Tokyo, Japan.
    The etiology of purpura in Sjögren syndrome (SS) includes cryoglobulinemia, hypergammaglobulinemia, and leukocytoclastic vasculitis (LCV). The clinical symptoms of LCV associated with SS comprise palpable or nonpalpable purpura and urticarial vasculitis. Here, we report a case of LCV presenting as erythema gyratum repens (EGR)-like purpura in a 62-year-old woman with rheumatoid arthritis and SS. Read More

    Eruptive Seborrheic Keratoses Restricted to Plaque/Patch-Stage Mycosis Fungoides.
    Case Rep Dermatol 2017 May-Aug;9(2):35-39. Epub 2017 Jun 8.
    Department of Dermatology, CHU Sart Tilman, University of Liège, Liège, Belgium.
    Eruptive seborrheic keratoses (ESK) are rare in dermatology. They are usually inflammatory in nature and may be encountered as Leser-Trélat sign. ESK may also be simultaneously observed with hepatic angiomas, chemotherapy, segmental neurofibromatosis, HIV or erythrodermic pityriasis rubra pilaris, psoriasis, and drug eruption. Read More

    A Case of Facial Partial Unilateral Lentiginosis Treated with Low-Fluence 1,064 nm Q-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser.
    Case Rep Dermatol 2017 May-Aug;9(2):30-34. Epub 2017 Jun 1.
    Department of Dermatology, Cheil General Hospital and Women's Healthcare Center, Dankook University College of Medicine, Cheonan, Republic of Korea.
    Partial unilateral lentiginosis (PUL) is an unusual pigmentary disorder characterized by numerous lentigines grouped within an area of normal skin. Although treatment is not necessary, many patients with facial PUL seek medical help for cosmetic reasons. There is no established standard treatment for PUL. Read More

    Infliximab-Induced Aseptic Meningitis during the Treatment of Psoriatic Arthritis.
    Case Rep Dermatol 2017 May-Aug;9(2):26-29. Epub 2017 May 22.
    aDepartment of Dermatology, Shonan Fujisawa Tokushukai Hospital, Fujisawa, Japan.
    A 42-year-old Japanese man presented with persistent headache during treatment for psoriatic arthritis (PsA) with infliximab. Treatment with infliximab was initiated 3 years before and the psoriatic skin lesions with arthritis were well controlled. However, after 21 doses of infliximab, the skin lesions and joint pain exacerbated and became intractable. Read More

    Successful Treatment of Chronic Staphylococcus aureus-Related Dermatoses with the Topical Endolysin Staphefekt SA.100: A Report of 3 Cases.
    Case Rep Dermatol 2017 May-Aug;9(2):19-25. Epub 2017 May 22.
    Department of Dermatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.
    Staphylococcus aureus plays an important role in skin and soft tissue infections and contributes to the pathophysiology of complex skin disorders such as atopic dermatitis. Bacterial resistance against commonly used antibiotics has increased considerably in the last decades demanding alternative treatment approaches. We present 3 cases where patients with chronic and recurrent S. Read More

    Sweet's Syndrome Successfully Treated with Granulocyte and Monocyte Adsorption Apheresis.
    Case Rep Dermatol 2017 May-Aug;9(2):13-18. Epub 2017 May 22.
    aDepartment of Dermatology, Gifu University Graduate School of Medicine, Gifu, Japan.
    Sweet's syndrome is a neutrophilic dermatosis characterized by an abrupt onset of painful erythematous lesions showing neutrophilic infiltrates in the dermis. Fever and an elevated neutrophil level are generally observed. Sweet's syndrome may be idiopathic, malignancy-associated, or drug-induced (mainly involving granulocyte colony-stimulating factor (G-CSF) administration). Read More

    Cutaneous Corynebacterium Infection Presenting with Disseminated Skin Nodules and Ulceration.
    Case Rep Dermatol 2017 May-Aug;9(2):8-12. Epub 2017 May 16.
    aDepartment of Dermatology, University Hospital Zurich, Zurich, Switzerland.
    In the context of the European migrant crisis, more and more cases of cutaneous diphtheria are seen. A typical presentation includes painful cutaneous ulcerations with grayish-whitish pseudomembranes. Here we present 2 male Eritrean patients suffering from cutaneous nontoxigenic Corynebacterium diphtheriae (patient 1) and Corynebacterium striatum (patient 2) infection. Read More

    Overlapping DRESS and Stevens-Johnson Syndrome: Case Report and Review of the Literature.
    Case Rep Dermatol 2017 May-Aug;9(2):1-7. Epub 2017 May 8.
    Department of Dermatology and Venereology, Erasme Hospital, ULB, Brussels, Belgium.
    Drug-induced severe cutaneous adverse reactions (SCARs) include acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS), and epidermal necrolysis (Stevens-Johnson syndrome [SJS], toxic epidermal necrolysis). The identification of the causal drug is crucial in order to avoid further exposure, but making the right differential diagnosis of the type of SCAR is equally important since treatment, follow-up, and prognosis of different SCARs are not the same. These syndromes are distinct entities with different clinical, biological, and histological patterns, but sometimes the early distinction between 2 SCARs can be extremely challenging, and overlapping conditions could therefore be taken into consideration, although true overlapping SCARs are very rare when using strict diagnostic criteria (described by the RegiSCAR group). Read More

    Panniculitis Associated with MEK Inhibitor Therapy: An Uncommon Adverse Effect.
    Case Rep Dermatol 2017 Jan-Apr;9(1):80-85. Epub 2017 Mar 21.
    aDepartment of Dermatology, Université Paul Sabatier-Toulouse III et Institut Universitaire du Cancer de Toulouse, Toulouse, France.
    The combination of MEK inhibitor (cobimetinib, trametinib) and BRAF inhibitor (vemurafenib, dabrafenib) is now the first-line treatment in patients with BRAF V600-mutated metastatic melanoma. This association reduces cutaneous adverse events induced by BRAF inhibitors alone, including photosensitivity, hand-foot syndrome, hyperkeratosis, alopecia, skin papillomas, keratoacanthomas, and squamous-cell carcinomas. While panniculitis has exceptionally been reported with BRAF inhibitors, this rare side effect has never been described with the use of MEK inhibitors. Read More

    Angioimmunoblastic T-Cell Lymphoma Mimicking Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS Syndrome).
    Case Rep Dermatol 2017 Jan-Apr;9(1):74-79. Epub 2017 Mar 21.
    aDepartment of Dermatology, University Hospital Zurich, Zurich, Switzerland.
    Angioimmunoblastic T-cell lymphoma (AITCL) is a rare, aggressive lymphoma which derives from follicular helper T cells, commonly affecting the elderly population. It accounts for 2% of all non-Hodgkin lymphomas, with a reported 5-year overall survival rate of less than 30%. Very often, the clinical picture of AITCL encompasses systemic symptoms such as generalized lymphadenopathy, hepatosplenomegaly, skin rash, anemia, and polyclonal hypergammaglobulinemia. Read More

    Necrolytic Acral Erythema in Seronegative Hepatitis C.
    Case Rep Dermatol 2017 Jan-Apr;9(1):69-73. Epub 2017 Mar 17.
    Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
    Necrolytic acral erythema (NAE) is a distinctive skin disorder. The exact cause and pathogenesis is still unclear. Most studies report an association of NAE with hepatitis C virus (HCV) infection. Read More

    Flare-Up of Rheumatoid Arthritis by Anti-CTLA-4 Antibody but Not by Anti-PD1 Therapy in a Patient with Metastatic Melanoma.
    Case Rep Dermatol 2017 Jan-Apr;9(1):65-68. Epub 2017 Mar 9.
    aDepartment of Dermatology, University Hospital of Zürich, Zurich, Switzerland.
    A 47-year-old female patient with rheumatoid arthritis (RA) treated with methotrexate, was diagnosed with metastatic melanoma. After surgical removal of the tumor, the patient started treatment with ipilimumab while methotrexate was stopped. One week after initiation of ipilimumab, the patient developed typical symptoms of RA. Read More

    Visual Loss Induced by Adalimumab Used for Plaque Psoriasis.
    Case Rep Dermatol 2017 Jan-Apr;9(1):60-64. Epub 2017 Mar 3.
    Maimonides Medical Center, Brooklyn, New York, USA.
    A 61-year-old Caucasian male with severe plaque psoriasis without joint involvement was initiated on adalimumab therapy. Shortly thereafter he presented to the emergency room with acute loss of vision in the right eye. A comprehensive systemic workup was instituted which included magnetic resonance imaging (MRI) with and without gadolinium of the brain and orbits. Read More

    Psoriatic Alopecia in a Patient with Systemic Lupus Erythematosus.
    Case Rep Dermatol 2017 Jan-Apr;9(1):51-59. Epub 2017 Mar 3.
    Division of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
    Psoriasis is a chronic, recurrent, and relatively common inflammatory dermatologic condition, which demonstrates various clinical manifestations including hair loss. It was once believed that alopecia was not a presentation of scalp psoriasis, but it is now widely accepted that psoriatic alopecia exists. Although the majority of patients get hair regrowth, it can potentially lead to permanent hair loss. Read More

    Pruritic Urticarial Papules and Plaques of Pregnancy Occurring Postpartum Treated with Intramuscular Injection of Autologous Whole Blood.
    Case Rep Dermatol 2017 Jan-Apr;9(1):151-156. Epub 2017 Apr 27.
    Department of Dermatology, Cheil General Hospital and Women's Healthcare Center, Dankook University College of Medicine, Cheonan, Republic of Korea.
    Pruritic urticarial papules and plaques of pregnancy (PUPPP) is one of the most common diseases associated with pregnancy. In most cases, the skin lesions develop in the third trimester of primigravidas. There are no systemic alterations seen in PUPPP; however, most patients report severe pruritus. Read More

    The Rare Case of Pemphigus Vegetans in Association with Malnutrition Children in the Multidisciplinary Management.
    Case Rep Dermatol 2017 Jan-Apr;9(1):145-150. Epub 2017 Apr 27.
    Division of Allergy-Immunology, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Bandung, Indonesia.
    Pemphigus vegetans is a clinical variant of pemphigus vulgaris, accounting for 1-2% of all very rare pemphigus cases in children. The involvement of the oral mucosa in this disease is usually accompanied by severe pain that aggravates the patient's malnourished condition. Conversely, malnutrition may also reduce vulnerability towards autoimmune diseases. Read More

    Interruption of Sneddon-Wilkinson Subcorneal Pustulation with Infliximab.
    Case Rep Dermatol 2017 Jan-Apr;9(1):140-144. Epub 2017 Apr 27.
    aDepartment of Dermatology, University Hospital of Zurich, Zurich, Switzerland.
    Subcorneal pustular dermatosis (SCPD, Sneddon-Wilkinson disease) is a rare chronic-relapsing skin disorder that typically manifests as flaccid sterile pustules without systemic symptoms. Although the accumulation of neutrophils is acknowledged to be a hallmark of SCPD, its exact pathomechanism is still not known. Several chemotactic factors have been implicated in neutrophil recruitment and invasion, including the proinflammatory cytokine TNF-α. Read More

    Rapid Involution of Pustules during Topical Steroid Treatment of Acute Generalized Exanthematous Pustulosis.
    Case Rep Dermatol 2017 Jan-Apr;9(1):135-139. Epub 2017 Apr 27.
    Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland.
    Acute generalized exanthematous pustulosis (AGEP) is a dramatic generalized pustular rash of severe onset, which is considered a serious cutaneous adverse reaction to drugs. However, even though the clinical features are impressive and are often accompanied by systemic inflammation, it can be controlled quickly and safely by topical steroids subsequent to interruption of the offending drug. Here, we describe the management of a case and the evolution of the pustular rash. Read More

    Isolated Actinic Lichen Planus of the Lower Lip.
    Case Rep Dermatol 2017 Jan-Apr;9(1):131-134. Epub 2017 Apr 27.
    National University Hospital, Singapore, Singapore.
    Oral lichen planus (LP) is a common manifestation in patients with LP; however, isolated lip LP is rare and may mimic other conditions such as lichenoid drug eruptions, actinic cheilitis, and early carcinoma in situ in the absence of typical skin lesions. Actinic lichen planus (ALP) is a variant of LP occurring on light-exposed areas in patients with dark skin. We report the case of a Chinese female with isolated ALP of the lower lip, mimicking herpes simplex infection at presentation. Read More

    Atypical Clinical and Serological Manifestation of Pemphigus Vegetans: A Case Report and Review of the Literature.
    Case Rep Dermatol 2017 Jan-Apr;9(1):121-130. Epub 2017 Apr 27.
    aDepartment of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.
    Pemphigus vegetans (PVeg) is a rare variant of pemphigus vulgaris characterized by pustules and/or papillomatous vegetations, preferentially affecting intertriginous and periorificial areas. Exceptional manifestations may be misdiagnosed resulting in delayed diagnosis and treatment. Diagnosis is confirmed by immunofluorescence and detection of anti-desmoglein (Dsg) 3 and/or anti-Dsg1 antibodies. Read More

    Fuchs Syndrome: Medical Treatment of 1 Case and Literature Review.
    Case Rep Dermatol 2017 Jan-Apr;9(1):114-120. Epub 2017 Apr 18.
    Department of Odontology, University Hospital of Montpellier, Montpellier, France.
    Fuchs syndrome is a particular type of erythema multiforme major; the lesions are only found on the mucosae and specifically affect oral, ocular, and genital mucosae. The cause is not always immediately apparent, which is why this pathology requires a rigorous, detailed clinical examination to eliminate a differential diagnosis. The severity of the symptoms, particularly of oral and ocular symptoms, requires immediate treatment. Read More

    A Case of Subcutaneous Sarcoidosis Occurring along the Superficial Veins of the Forearms: A Distinctive Cutaneous Manifestation Masquerading Venous Tropic Action in the Underlying Systemic Disease?
    Case Rep Dermatol 2017 Jan-Apr;9(1):108-113. Epub 2017 Apr 7.
    aDepartment of Dermatology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
    Sarcoidosis is a multisystem disease of unknown etiology, developing granulomas in any tissues and organs. Approximately 25% of sarcoidosis patients have cutaneous involvement with various clinical manifestations, which are categorized into specific or nonspecific diseases based on the histopathology; the former represents the typical sarcoid granulomas. Subcutaneous sarcoidosis is one of the specific skin lesions and often affects extremities, to a much lesser extent with other anatomical sites. Read More

    Concomitant B Hairy Cell Leukemia and Mycosis Fungoides in an Elderly Man.
    Case Rep Dermatol 2017 Jan-Apr;9(1):103-107. Epub 2017 Apr 7.
    aDivision of Dermatology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
    The development of both a T- and B-cell lymphoproliferative disorder in one patient is an unlikely coincidence due to the low prevalence of each malignancy. We report a 65-year-old man with a previously documented history of B hairy cell leukemia, who presented with a new-onset acneiform eruption of his scalp, face, trunk, back, and extremities. Routine pathology of the skin lesions with immunohistochemical stains and molecular studies were consistent with a folliculotropic mycosis fungoides. Read More

    Painful Leg Ulceration in a Poorly Controlled Hypertensive Patient: A Case Report of Martorell Ulcer.
    Case Rep Dermatol 2017 Jan-Apr;9(1):95-102. Epub 2017 Apr 7.
    bFiona Stanley Hospital, Murdoch, WA, Australia.
    Martorell ulcer is a form of lower limb ulceration, preceded by a small area of excruciating pain. It often appears as a solitary lesion on the outer aspect of the lower limb, and is primarily associated with poorly controlled hypertension and diabetes. Treatment of the ulcer involves awareness and early correct diagnosis, adequate control of blood pressure, management of infection, and wound care. Read More

    Papulonodular Secondary Syphilis Presenting as Multiple Distinct Cutaneous Lesions in an HIV-Positive Transgender Woman.
    Case Rep Dermatol 2017 Jan-Apr;9(1):90-94. Epub 2017 Mar 29.
    Department of Dermatology, Weill Cornell Medical College, New York, New York, USA.
    We present the first reported case of papulonodular secondary syphilis in an HIV-positive transgender female. Syphilis is classified into primary, secondary, latent, and tertiary stages, with secondary syphilis having notably diverse cutaneous manifestations. Our patient presented with diverse lesions throughout her body, all pathologically consistent with papulonodular secondary syphilis. Read More

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