2,135 results match your criteria Case Reports in Medicine [Journal]


A Unique Case of Complete Atrioventricular Block Rapidly Progressing to Diastolic and Systolic Dysfunction in Cardiac Sarcoidosis.

Case Rep Med 2019 6;2019:4341098. Epub 2019 Mar 6.

Internal Medicine, John H. Stroger Jr. Hospital of Cook County, Chicago, IL 60612, USA.

Sarcoidosis is a multisystem granulomatous disease that most commonly affects the lungs but can affect other organs including the heart due to granuloma infiltration. Atrioventricular block is a common manifestation of cardiac sarcoidosis which can progress to sudden cardiac death. We report a case of cardiac sarcoidosis presenting as complete heart block, progressing to diastolic and systolic dysfunction without extracardiac manifestations early in the disease. Read More

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http://dx.doi.org/10.1155/2019/4341098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431385PMC
March 2019
1 Read

Compartment Syndrome following Snakebite Leads to Decompressive Fasciotomies.

Case Rep Med 2019 4;2019:6324569. Epub 2019 Mar 4.

Department of Public Health and Forensic Sciences, and Medical Education, Faculty of Medicine, University of Porto, Porto, Portugal.

Snakebite envenoming is a neglected tropical disease with relevant morbidity and mortality. In this report, we illustrate the clinical course of a suspected snakebite envenoming of a patient that evidenced severe pain, edema, pallor, regional lymphadenopathy, ecchymosis, myonecrosis, and bullous erythema in the right lower limb, specially around the fang marks. The clinical course progressed to compartment syndrome followed with decompressive fasciotomies to reduce pressure within the affected compartment. Read More

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http://dx.doi.org/10.1155/2019/6324569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425384PMC
March 2019
2 Reads

Partial Trisomy of Chromosome 13 with a Novel Translocation (8 ; 13) and Unique Clinical Presentation in a Palestinian Infant.

Case Rep Med 2019 26;2019:4561761. Epub 2019 Feb 26.

Genetic Diagnosis Lab, Islamic University of Gaza, Gaza Strip, State of Palestine.

Partial trisomy 13 is a rare syndrome that usually culminates in death within the first six months of the infant's life. We present a rare case of partial trisomy 13q with exclusive clinical manifestations. The full-term male baby was born by normal vaginal delivery, his birth weight was 3500 grams, and head circumference was 30 cm. Read More

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http://dx.doi.org/10.1155/2019/4561761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413401PMC
February 2019
1 Read

Sitagliptin and Simvastatin Interaction Causing Rhabdomyolysis and AKI.

Case Rep Med 2019 26;2019:2601537. Epub 2019 Feb 26.

Division of Pulmonary and Critical Care, Pikeville Medical Center, Pikeville, KY, USA.

We report a case of rhabdomyolysis and severe acute kidney injury (AKI) requiring dialysis in a 69-year-old male who was recently started on sitagliptin while on chronic simvastatin therapy. This potential interaction is not included in the package insert for sitagliptin. A comprehensive literature review revealed six previous reports of rhabdomyolysis due to drug interaction between sitagliptin and statins including simvastatin, lovastatin, and atorvastatin. Read More

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http://dx.doi.org/10.1155/2019/2601537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413355PMC
February 2019
3 Reads

Transpedicular Endoscopic Surgery for Highly Downmigrated L5-S1 Disc Herniation.

Authors:
Guntram Krzok

Case Rep Med 2019 25;2019:5724342. Epub 2019 Feb 25.

Department of Orthopedic Surgery, SRH Hospital Waltershausen-Friedrichroda, Friedrichroda, Germany.

Endoscopic surgery for highly downmigrated disc herniation at level L5-S1 is a challenging technique. Most surgeons prefer the interlaminar access because of the special anatomy of the L5-S1 disc level, i.e. Read More

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http://dx.doi.org/10.1155/2019/5724342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410447PMC
February 2019

A New Differential Diagnosis: Synthetic Cannabinoid-Associated Gross Hematuria.

Case Rep Med 2019 24;2019:6327819. Epub 2019 Feb 24.

Midwestern University, 555 31st St., Downers Grove, IL 60515, USA.

Recreational use of synthetic cannabinoids (SCs), also known as "K2" or "Spice," is becoming a major public-health concern due to their potential for abuse and harmful consequences. New substances are constantly being added to the content of SCs. The dearth of information on these newly added contents as they are introduced into the black market hinders risk assessments of these compounds. Read More

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http://dx.doi.org/10.1155/2019/6327819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409059PMC
February 2019
2 Reads

Artemether/Lumefantrine for the Treatment of in a Patient on Hemodialysis.

Case Rep Med 2019 12;2019:1326171. Epub 2019 Feb 12.

Infectious Diseases Department, Hospital Prof. Doutor Fernando Fonseca, EPE, IC 19, 2720-276 Amadora, Portugal.

The combination of artemether/lumefantrine is indicated for the treatment of acute uncomplicated malaria. There have been no clinical trials to assess the efficacy of this medication in patients with renal impairment. While it is unlikely that artemether/lumefantrine would be removed during dialysis, clinical experience regarding drug use in this setting is limited. Read More

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http://dx.doi.org/10.1155/2019/1326171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390258PMC
February 2019

Late Response of Antiretroviral Therapy in an HIV-1-Infected Patient due to Hepatitis B and C Coinfections: The First Case Report in Nepal.

Case Rep Med 2019 11;2019:2070973. Epub 2019 Feb 11.

Sukraraj Tropical & Infectious Disease Hospital, Teku, Kathmandu, Nepal.

Aim: Dual coinfection of HCV and HBV in HIV-1-infected population is a leading cause of morbidity and mortality. Also, they share routes of HIV transmission; however, it might be associated with an independent factor like injecting drug use for HCV and unsafe sex for HBV. This case report suggests that hepatitis virus coinfection may lead to late response of antiretroviral therapy (ART) in HIV-1 patients. Read More

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http://dx.doi.org/10.1155/2019/2070973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388324PMC
February 2019
1 Read

Case Report on Pleural Empyema Thoracis and Urinary Tract Infection Caused by from Lagos, Nigeria.

Case Rep Med 2019 7;2019:5321484. Epub 2019 Feb 7.

Molecular Biology & Biotechnology Department, Nigerian Institute of Medical Research, Lagos, Nigeria.

has been implicated as an important cause of invasive diseases such as septicaemia in neonates and immune-compromised adults with high risk of misdiagnosis, mistreatment, and poor outcomes. Here, we report three new cases of infections in three different hospitalised patients with empyema thoracis (one case) and urinary tract infections (two cases) in a tertiary Hospital in Lagos, Nigeria, and the diagnosis was confirmed with the MALDI-TOF MS instrument. The patients were admitted and treated with parenteral antibiotics (ciprofloxacin, cefotaxime, and ceftriaxone) and discharged after clinical cure. Read More

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http://dx.doi.org/10.1155/2019/5321484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383417PMC
February 2019

Endovascular Treatment of Ruptured Renal Artery Aneurysm: A Case-Based Literature Review.

Case Rep Med 2019 6;2019:3738910. Epub 2019 Feb 6.

Resident, Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.

Renal artery aneurysms are extremely uncommon with a reported incidence of less than one percent in general population. They are being more frequently detected due to increasing availability and use of abdominal imaging. Renal artery aneurysm rupture is an extremely unusual cause of acute flank pain with hemodynamic instability. Read More

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http://dx.doi.org/10.1155/2019/3738910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381552PMC
February 2019
1 Read

Myocarditis Caused by in the Absence of Endocarditis: Case Report and Review of the Literature.

Case Rep Med 2019 10;2019:3701016. Epub 2019 Feb 10.

Internal Medicine Department, University Hospital of Patras, Rio, Greece.

Brucellosis remains an important public health problem with endemic characteristics in many countries. Brucellosis can affect almost all organs and systems of human body. Cardiac complications are unusual, occurring in less than 2% of patients and usually manifest as endocarditis. Read More

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http://dx.doi.org/10.1155/2019/3701016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387729PMC
February 2019
1 Read

Gitelman Syndrome: A Rare Cause of Seizure Disorder and a Systematic Review.

Case Rep Med 2019 5;2019:4204907. Epub 2019 Feb 5.

Resident Physician, Abington Hospital-Jefferson Health, Abington, PA, USA.

Gitelman syndrome is one of the few inherited causes of metabolic alkalosis due to salt losing tubulopathy. It is caused by tubular defects at the level of distal convoluted tubules, mimicking a thiazide-like tumor. It usually presents in late childhood or in teenage as nonspecific weakness, fatigability, polyuria, and polydipsia but very rarely with seizures. Read More

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http://dx.doi.org/10.1155/2019/4204907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379858PMC
February 2019
1 Read

Misdiagnosis: Acute Chest Syndrome That Evolved into Acute Respiratory Distress Syndrome in a Patient without a Documented History of Hemoglobinopathy.

Case Rep Med 2019 3;2019:2893056. Epub 2019 Feb 3.

Program Director, Pulmonary and Critical Care Fellowship, Newark Beth Israel Medical Center, Newark, NJ, USA.

Acute chest syndrome (ACS) is a feared complication of sickle cell disease. Here is a case of a patient who presented with symptoms suggestive of acute chest syndrome yet had a delayed diagnosis presumably due to the lack of documented history of sickle cell disease of the patient, consequently evolving into acute respiratory distress syndrome (ARDS). He was subsequently diagnosed with heterozygous sickle cell SC disease on hemoglobin electrophoresis. Read More

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http://dx.doi.org/10.1155/2019/2893056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378019PMC
February 2019
2 Reads

Treatment of Ethylene Glycol Poisoning with Oral Ethyl Alcohol.

Case Rep Med 2019 30;2019:7985917. Epub 2019 Jan 30.

Senior Resident, Department of Internal Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, India.

Ethylene glycol poisoning is not uncommon in India. The ill effects are primarily caused by its toxic metabolites: glycolic acid and oxalic acid. A 70-year-old female presented to our hospital with ataxia after ingestion of ethylene glycol. Read More

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http://dx.doi.org/10.1155/2019/7985917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374870PMC
January 2019

Severe Influenza A(H1N1) Virus Infection Complicated by Myositis, Refractory Rhabdomyolysis, and Compartment Syndrome.

Case Rep Med 2019 30;2019:1540761. Epub 2019 Jan 30.

Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut 06510, USA.

Myositis is a rare and morbid complication of influenza infection that can rapidly progress to rhabdomyolysis with acute renal failure. Here, we describe a 35-year-old obese woman with severe influenza A(H1N1) virus infection complicated by myositis, refractory rhabdomyolysis, and compartment syndrome. Read More

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http://dx.doi.org/10.1155/2019/1540761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374868PMC
January 2019
1 Read

"Crack, Reduce, and Implant": A Safe Phaco Technique in a Case with Hard Brown Cataract.

Case Rep Med 2019 27;2019:9043417. Epub 2019 Jan 27.

Department of Ophthalmology, Faculty of Medicine, Pamukkale University, Denizli, Turkey.

This report describes two maneuvers in different steps of phaco surgery in a case with hard cataract, which provide debulking of the central dense nucleus and prevents posterior capsule rupture (PCR). In the current case, clear corneal incisions were created, and anterior chamber was filled with ophthalmic viscosurgical device (OVD). Anterior capsule was punctured, and capsulorhexis was completed. Read More

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http://dx.doi.org/10.1155/2019/9043417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369501PMC
January 2019

Diffuse Alveolar Hemorrhage Caused by Warfarin after Rifampicin Discontinuation.

Case Rep Med 2019 23;2019:4917856. Epub 2019 Jan 23.

Department of General Medicine, Oita University Faculty of Medicine, Yufu 879-5593, Japan.

An 83-year-old man under warfarin therapy presented for assessment of prolonged prothrombin time and cough. High-resolution computed tomography findings of the chest showed diffuse alveolar hemorrhage. His international normalized ratio (INR) was 11. Read More

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http://dx.doi.org/10.1155/2019/4917856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364120PMC
January 2019
2 Reads

A Rare Occurrence of Isolated Brain Metastases from Gastric Cancer.

Case Rep Med 2019 20;2019:8075421. Epub 2019 Jan 20.

Tufts University School of Medicine, Boston, MA 02111, USA.

Background: Gastric cancer is the fourth most common cancer worldwide and the second most common cause of cancer-related death. The majority of newly diagnosed gastric cancer cases present either as locally advanced tumor growth or with distant metastases.

Case Report: Here, we describe a case of isolated brain metastases in a male patient with gastric cancer. Read More

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http://dx.doi.org/10.1155/2019/8075421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360578PMC
January 2019
1 Read

Dravet Syndrome in Lebanon: First Report on Cases with Mutations.

Case Rep Med 2019 21;2019:5270503. Epub 2019 Jan 21.

Institut Jérôme Lejeune, Paris, France.

Dravet syndrome, also known as severe myoclonic epilepsy in infancy, is a rare disease characterized by the appearance of different types of seizures in a healthy baby, triggered by various factors and stressful events. We report 8 Lebanese cases referred for molecular analysis of the gene. Results were positive in 7 cases and revealed de novo variants at the heterozygous state in different exons of the gene for all except one, where the variant was intronic. Read More

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http://dx.doi.org/10.1155/2019/5270503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360541PMC
January 2019
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A Case of Alveolar Bleeding from Clotting Abnormality by Cefmetazole.

Case Rep Med 2019 21;2019:3574064. Epub 2019 Jan 21.

Department of Internal Medicine, Suwa Central Hospital, Chino, Nagano, Japan.

Cephalosporins are one of the most commonly used first-line antibiotics. In this report, we describe the case of a patient who developed alveolar bleeding due to clotting abnormality following the use of cefmetazole, one of cephalosporins containing an -methylthiotetrazole (NMTT) side chain. Compared to other antibiotics, cephalosporins with an NMTT side chain cause a higher degree of bleeding events. Read More

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http://dx.doi.org/10.1155/2019/3574064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360626PMC
January 2019
1 Read

45,X/46,XY Mosaicism and Normozoospermia in a Patient with Male Phenotype.

Case Rep Med 2019 20;2019:2529080. Epub 2019 Jan 20.

The Fertility Clinic Skive Regional Hospital, Skive Regional Hospital, Resenvej 25, 7800 Skive, Denmark.

The phenotypic spectrum of 45,X/46,XY mosaic males varies greatly. Previous reports have only described cases with either oligozoospermia, growth retardation, or elevated gonadotropins. However, the present case presented with normozoospermia, and normal height, sperm DNA fragmentation index (DFI), and gonadotropins. Read More

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http://dx.doi.org/10.1155/2019/2529080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360613PMC
January 2019
1 Read

Separating Acute Rheumatic Fever from Nonrheumatic Streptococcal Myocarditis.

Case Rep Med 2019 16;2019:4674875. Epub 2019 Jan 16.

Department of Internal Medicine, University of Missouri-Kansas City, Kansas City, MO, USA.

Introduction: Streptococcal pharyngitis has been historically complicated with systemic involvement manifesting as acute rheumatic fever, which is a serious condition that can lead to permanent damage to heart valves. A recent association between streptococcal pharyngitis and nonrheumatic heart disease is emerging in literature. We present a case of nonrheumatic streptococcal myocarditis diagnosed using cardiac MRI. Read More

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http://dx.doi.org/10.1155/2019/4674875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360030PMC
January 2019
1 Read

A Novel Mutation in the Adult-Onset Alexander's Disease Gene.

Case Rep Med 2019 10;2019:2986538. Epub 2019 Jan 10.

Brookwood Baptist Health Medical Education, 817 Princeton Ave SW, POB2, Suite 106, Birmingham, AL 35211, USA.

The case describes a 25-year-old Caucasian female diagnosed with Alexander's disease (AxD) as an outpatient after extensive inpatient workup. Her presenting complaints included incontinence, clumsiness, seizures, dysphagia, and dysarthria. She was also found to have pancytopenia and dysautonomia. Read More

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http://dx.doi.org/10.1155/2019/2986538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348877PMC
January 2019
1 Read

Cardiac Arrest in the Airport Revealing Cocaine Body Packing: A Case Report.

Case Rep Med 2019 6;2019:6183154. Epub 2019 Jan 6.

Department of Medical and Toxicological Critical Care, Lariboisière Hospital, Paris-Diderot University, INSERM UMRS1144, Paris, France.

Ingestion of large amounts of cocaine packages is a well-known method for cross-border transportation. Intestinal obstruction and life-threatening sympathomimetic toxidrome including seizures, ventricular dysrhythmia, and cardiac arrest resulting from the rupture of cocaine packages may occur. Here, we report a case of a 34-year-old pregnant woman who had a sudden cardiac arrest while waiting for her bags at Paris-Charles de Gaulle Airport, France. Read More

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http://dx.doi.org/10.1155/2019/6183154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339722PMC
January 2019
2 Reads

Hemorrhagic Spinal Schwannoma in Thoracolumbar Area with Total Paraplegia.

Case Rep Med 2019 2;2019:7190739. Epub 2019 Jan 2.

Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Hemorrhagic schwannoma in the medulla spinalis is a rare occurrence. It is a variant of the slow-growing nerve sheath tumor that usually has subtle clinical symptoms. Injury to the spinal schwannoma that was previously suspected by spinal manipulations may accelerate the progression of symptoms and cause an acute presentation of paraplegia. Read More

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http://dx.doi.org/10.1155/2019/7190739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334320PMC
January 2019
2 Reads

A Case of Parvovirus-Related Haemophagocytic Lymphohistiocytosis in a Patient with HbH Disease.

Case Rep Med 2018 24;2018:8057045. Epub 2018 Dec 24.

Department of Haematology, Tan Tock Seng Hospital, Singapore.

Hemophagocytic lymphohistiocytosis (HLH) is rare and life-threatening medical emergency. Parvovirus infection is rarely associated with HLH. We report a case of parvovirus-related HLH in a patient with alpha thalassaemia (HbH disease). Read More

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https://www.hindawi.com/journals/crim/2018/8057045/
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http://dx.doi.org/10.1155/2018/8057045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323427PMC
December 2018
5 Reads

Sarcoidosis Presenting as Acute Respiratory Distress Syndrome.

Case Rep Med 2018 23;2018:6465180. Epub 2018 Dec 23.

Department of Pulmonary and Critical Care Medicine-Jefferson Health, Abington, PA, USA.

Sarcoidosis is a multisystem granulomatous disease of unknown origin. It typically involves the lungs and mediastinal lymph nodes in a chronic fashion. However, acute syndrome has been reported possibly in response to systemic release of proinflammatory cytokines. Read More

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http://dx.doi.org/10.1155/2018/6465180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323477PMC
December 2018
1 Read

Disseminated Histoplasmosis with Miliary Histoplasmosis, Neurohistoplasmosis, and Bacteremia in Probable Neurosarcoidosis.

Authors:
Peter V Bui

Case Rep Med 2018 11;2018:3162403. Epub 2018 Dec 11.

Department of Emergency Medicine, University of Michigan, Ann Arbor, MI, USA.

Introduction: Neurosarcoidosis, either isolated or as part of systemic sarcoidosis, is an uncommon entity and has diagnostic uncertainty. Treatment for neurosarcoidosis can increase the risk of infections, including fungal infections such as disseminated histoplasmosis. Neurosarcoidosis may further predispose patients to infections of the central nervous system. Read More

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http://dx.doi.org/10.1155/2018/3162403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311783PMC
December 2018
5 Reads

Seizure and Acute Vision Loss in a Filipino Lupus Patient: A Case of Posterior Reversible Encephalopathy Syndrome with Intraparenchymal Hemorrhage.

Case Rep Med 2018 9;2018:4238676. Epub 2018 Dec 9.

Section of Rheumatology, Department of Medicine, UP-Philippine General Hospital, Manila, Philippines.

Posterior reversible encephalopathy syndrome (PRES) is a rare and poorly understood neurologic condition that has been described in some patients with systemic lupus erythematosus (SLE). Intracerebral hemorrhage is a unique and atypical presentation of PRES and has been described only in a small number of patients with SLE. We present the case of a 33-year-old female, diagnosed with SLE and active nephritis, who was admitted for seizures. Read More

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https://www.hindawi.com/journals/crim/2018/4238676/
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http://dx.doi.org/10.1155/2018/4238676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304919PMC
December 2018
12 Reads

Posterior Reversible Encephalopathy Syndrome due to Hypomagnesemia: A Case Report and Literature Review.

Case Rep Med 2018 29;2018:1980638. Epub 2018 Nov 29.

Department of Neurology, St. Josef Hospital, The Academic Hospital of Duisburg-Essen University, Mülheimer Strasse 83, 46045 Oberhausen, Germany.

Background: Hypomagnesemia can cause various unspecific neurological complications, which can lead to diagnostic confusion. One of these complications is the posterior reversible encephalopathy syndrome (PRES), which is extremely uncommon and has been reported only twice in the English-language literature.

Case Presentation: We report the case of a 60-year-old man who presented with PRES involving only the cerebellar hemispheres and associated with hypomagnesemia. Read More

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https://www.hindawi.com/journals/crim/2018/1980638/
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http://dx.doi.org/10.1155/2018/1980638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304829PMC
November 2018
17 Reads

Analysis of Treatment of 3 Patients with Acute-on-Chronic Liver Failure.

Case Rep Med 2018 22;2018:7421502. Epub 2018 Nov 22.

Department of Infectious Disease, General Hospital of the Yangtze River Shipping, Wuhan Brain Hospital, Wuhan 430010, China.

Acute-on-chronic liver failure (ACLF) is an acute liver decompensation that occurs within 4 weeks on the basis of chronic liver disease. At present, the treatments of ACLF include general supportive treatment, etiological treatment, prevention and treatment of complications, artificial liver treatment, and liver transplantation. Many studies suggest that stem cell therapy may become a new treatment for patients with ACLF. Read More

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https://www.hindawi.com/journals/crim/2018/7421502/
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http://dx.doi.org/10.1155/2018/7421502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282116PMC
November 2018
12 Reads

Toxicological and Biochemical Analyses of an Autopsy Case Involving Oral Overdose of Multiple Antidiabetic and Antihypertensive Drugs.

Case Rep Med 2018 25;2018:5864658. Epub 2018 Nov 25.

Department of Legal Medicine, Osaka City University Medical School, Asahi-machi 1-4-3, Abeno, Osaka 545-8585, Japan.

Oral antidiabetics can cause fatal hypoglycemia; although they can be chemically identified and quantified, biochemical investigations are important for assessing the biological consequences of an overdose. Such cases of overdose involving oral antidiabetics may involve other drugs for treating lifestyle-related diseases, particularly antihypertensives. Here, we report a toxicological and biochemical investigation of drugs and biochemical profiles in a fatal overdose involving multiple oral antidiabetics and antihypertensives. Read More

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https://www.hindawi.com/journals/crim/2018/5864658/
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http://dx.doi.org/10.1155/2018/5864658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286784PMC
November 2018
4 Reads

A Case Report of Acute Airway Compromise due to Subcutaneous Emphysema.

Case Rep Med 2018 25;2018:3103061. Epub 2018 Nov 25.

Cumming School of Medicine, University of Calgary, Alberta Health Services, Department of Surgery, South Health Campus, 4448 Front St SE, Calgary, AB T3M1M4, Canada.

In the acute management of a trauma patient, airway patency is of utmost importance. The present case describes a male patient who presented with delayed severe upper airway obstruction secondary to massive subcutaneous emphysema following blunt traumatic injury two days previously. Airway compromise is a rarely described but serious complication of subcutaneous emphysema. Read More

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http://dx.doi.org/10.1155/2018/3103061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286736PMC
November 2018
2 Reads

Bortezomib-Induced Pulmonary Toxicity: A Case Report and Review of Literature.

Case Rep Med 2018 25;2018:2913124. Epub 2018 Nov 25.

Department of Medicine, Wilmot Cancer Institute, University of Rochester, Rochester, NY, USA.

Bortezomib, a proteasome inhibitor, is an established therapy against multiple myeloma. Bortezomib-induced lung injury, although not appreciated during the introductory time of the medication, has now been highlighted in multiple case reports. The objective of this study is to report a case of bortezomib-induced lung injury, review current literature, and perform exploratory analysis. Read More

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http://dx.doi.org/10.1155/2018/2913124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286773PMC
November 2018
1 Read

A Rare Case of Monophasic Synovial Sarcoma of Thoracic Vertebra.

Case Rep Med 2018 18;2018:2313927. Epub 2018 Nov 18.

Raritan Bay Medical Center, Perth Amboy, NJ, USA.

Synovial sarcoma of spine is an extremely rare malignancy with poor prognosis. It is often metastatic at the time of presentation. Its relative rarity and histological resemblance to other tumors make it diagnostically challenging, requiring the need of immunohistochemistry and cytogenetics for definite diagnosis. Read More

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http://dx.doi.org/10.1155/2018/2313927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276405PMC
November 2018
1 Read

Chorea Hyperglycemia Basal Ganglia Syndrome in a 63-Year-Old Male.

Case Rep Med 2018 5;2018:9101207. Epub 2018 Nov 5.

U.S. Department of Veteran Affairs, Internal Medicine, 1970 Roanoke Blvd., Salem, VA 24153, USA.

Chorea hyperglycemia basal ganglia syndrome (CHBG) is a rare condition that manifests within the setting of uncontrolled nonketotic diabetes mellitus. The objective of this case report is to present a patient found to have CHBG and provide a timeline in terms of his workup and subsequent treatment. We also present a commentary on the current understanding of the pathophysiology and treatment and how this was applied to our patient. Read More

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http://dx.doi.org/10.1155/2018/9101207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247715PMC
November 2018
2 Reads

Reset Osmostat: A Challenging Case of Hyponatremia.

Case Rep Med 2018 4;2018:5670671. Epub 2018 Nov 4.

Woodlands Health Campus 2, Yishun Avenue 2, Singapore 768024.

Hyponatremia is the most common electrolyte abnormality seen in hospitalised patients with up to 15-20% of patients having a sodium level of less than 135 mmol/L (Reddy and Mooradian, 2009). Cases of hyponatremia were first described in the 1950s (George et al., 1955). Read More

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https://www.hindawi.com/journals/crim/2018/5670671/
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http://dx.doi.org/10.1155/2018/5670671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247647PMC
November 2018
8 Reads

Sarcoidosis and Its Splenic Wonder: A Rare Case of Isolated Splenic Sarcoidosis.

Case Rep Med 2018 5;2018:4628439. Epub 2018 Nov 5.

Texas A&M University, College Station, TX, USA.

Sarcoidosis is a systemic granulomatous disease of unknown etiology characterized by presence of noncaseating granulomas in the involved organs. The pulmonary interstitium is most commonly affected but extrapulmonary involvement can occur in almost any other organ system. Such an involvement can occur with or without the presence of pulmonary involvement, but isolated extrapulmonary involvement has been noted only in around 10% of cases. Read More

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http://dx.doi.org/10.1155/2018/4628439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247667PMC
November 2018
4 Reads

Rhabdomyolysis-Induced Acute Kidney Injury in Diabetic Emergency: Underdiagnosed and an Important Association to Be Aware of.

Case Rep Med 2018 31;2018:4132738. Epub 2018 Oct 31.

Department of Medicine, Internal Medicine Residency Program, Hackensack Meridian Health, Jersey Shore University Medical Center, Neptune, New Jersey 07753, USA.

Rhabdomyolysis is a potentially life-threatening clinical syndrome associated with muscle injury which can cause a leakage of intracellular contents, manifested from the range of being asymptomatic to a life-threatening condition causing acute kidney injury and severe electrolyte abnormalities. Rhabdomyolysis has been associated with both diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic nonketotic syndrome, though there is an increased association with rhabdomyolysis and acute kidney injury with hyperosmolar nonketonic state compared with patients with diabetic ketoacidosis. Common clinical manifestations are muscle pain, dark urine, and generalized weakness. Read More

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http://dx.doi.org/10.1155/2018/4132738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234448PMC
October 2018
3 Reads

Therapy with Ulipristal Acetate in a Hypertensive Patient.

Case Rep Med 2018 1;2018:1091520. Epub 2018 Nov 1.

Servicio de Obstetricia y Ginecología, Hospital Universitari Sagrat Cor, Barcelona, Spain.

Ulipristal acetate (UPA) is a medical therapy for patients with symptomatic uterine fibroids. The drug has shown efficacy in the control of heavy menstrual bleeding and, as a consequence, in anaemia improvement. We report the case of a hypertensive patient treated with two courses of UPA. Read More

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http://dx.doi.org/10.1155/2018/1091520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236705PMC
November 2018
2 Reads

Hip Mobilization at Preterm Age May Accelerate Developmental Dysplasia Recovery.

Case Rep Med 2018 29;2018:8625721. Epub 2018 Oct 29.

Department of Physical Therapy, Communication Sciences and Disorders and Occupational Therapy, Faculty of Medicine, University of São Paulo, Brazil.

Purpose: Few studies have described mobilization approaches in developmental dysplasia of the hip (DDH). The present study describes the hip mobilization of a preterm infant (born at 33 6/7 weeks of gestational age) diagnosed with DDH.

Design And Methods: During the 43-day hospital stay, the infant was seen twice a week (ten sessions, 20 minutes each). Read More

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http://dx.doi.org/10.1155/2018/8625721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231373PMC
October 2018
3 Reads

Sinking Skin Flap Syndrome: Phenomenon of Neurological Deterioration after Decompressive Craniectomy.

Case Rep Med 2018 23;2018:9805395. Epub 2018 Oct 23.

Department of Internal Medicine, Temple University, Conemaugh Memorial Medical Center, Johnstown, PA, USA.

Sinking skin flap syndrome is rare phenomenon that occurs in patients with large craniectomies. Alteration in normal anatomy and pathophysiology can result in wide variety of symptoms including altered mental status, hemodynamic instability, and dysautonomias. Management is largely conservative. Read More

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https://www.hindawi.com/journals/crim/2018/9805395/
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http://dx.doi.org/10.1155/2018/9805395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218751PMC
October 2018
26 Reads

Macrophage Activation Syndrome, Glomerulonephritis, Pericarditis, and Retinal Vasculitis as Initial Presentation of Systemic Lupus Erythematosus.

Case Rep Med 2018 26;2018:5979386. Epub 2018 Sep 26.

Department of Medicine, Mount Sinai St Luke's and Mount Sinai West, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Macrophage activation syndrome (MAS) is a rare manifestation of systemic lupus erythematosus (SLE) with potentially life-threatening consequences. To the best of our knowledge, this is the first case reported in literature for a constellation of MAS, glomerulonephritis, pericarditis, and retinal vasculitis as initial presentation of SLE. Despite extensive multisystem involvement of his disease, the patient responded well to initial steroid treatment, with mycophenolate mofetil successfully added as a steroid-sparing agent. Read More

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http://dx.doi.org/10.1155/2018/5979386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178166PMC
September 2018
5 Reads

Peritonitis: An Emerging Infection in Peritoneal Dialysis Patients.

Case Rep Med 2018 19;2018:3537283. Epub 2018 Sep 19.

Department of Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, 1945 Route 33, Neptune, NJ 07753, USA.

Recently, the incidence of () associated infection has increased significantly in hospital and ambulatory care settings in parallel to the increasing use of inappropriate antibiotics. According to the CDC, approximately 83,000 patients who developed . experienced at least one recurrence and 29,000 died within 30 days of the initial diagnosis. Read More

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https://www.hindawi.com/journals/crim/2018/3537283/
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http://dx.doi.org/10.1155/2018/3537283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169237PMC
September 2018
19 Reads

When a Seemingly Harmless Prescription Turns into Toxicity.

Case Rep Med 2018 16;2018:9724390. Epub 2018 Sep 16.

Department of Neurology, Albert Einstein Medical Center, Philadelphia, PA, USA.

Valacyclovir neurotoxicity is commonly seen in the elderly and those with impaired renal function. Differential diagnosis can be challenging as a myriad of medical conditions, including herpes zoster virus associated encephalitis, may present in a similar fashion. We present a case of a 71-year-old male who presented with altered mental status in the setting of recent herpes zoster eruption. Read More

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https://www.hindawi.com/journals/crim/2018/9724390/
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http://dx.doi.org/10.1155/2018/9724390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165624PMC
September 2018
29 Reads

The First Report of Multicentric Carpotarsal Osteolysis Syndrome Caused by Mutation in Asian.

Case Rep Med 2018 16;2018:6783957. Epub 2018 Sep 16.

Department of Pediatrics, Faculty of Medicine, Thammasat University, Bangkok, Thailand.

Multicentric carpotarsal osteolysis syndrome (MCTO) is a rare skeletal disorder characterized by aggressive osteolysis associated with progressive nephropathy. The early clinical presentation can mimic polyarticular juvenile idiopathic arthritis. Since 2012, mutations have been discovered in all MCTO patients. Read More

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https://www.hindawi.com/journals/crim/2018/6783957/
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http://dx.doi.org/10.1155/2018/6783957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164201PMC
September 2018
17 Reads

A Very Rare Complication of Hepatitis A Infection: Acute Myocarditis-A Case Report with Literature Review.

Case Rep Med 2018 13;2018:3625139. Epub 2018 Sep 13.

Internal Medicine Department, Beaumont Hospital, Royal Oak, MI, USA.

Hepatitis A is a common viral infection with a benign course but in rare cases can progress to acute liver failure. It usually presents with abdominal pain, nausea, vomiting, diarrhea, jaundice, anorexia, or asymptomatically, but it can also present atypically with relapsing hepatitis and prolonged cholestasis. In addition, extrahepatic manifestations have been reported, including urticarial and maculopapular rash, acute kidney injury, autoimmune hemolytic anemia, aplastic anemia, acute pancreatitis, mononeuritis, reactive arthritis, glomerulonephritis, cryoglobulinemia, Guillain-Barre syndrome, and pleural or pericardial effusion. Read More

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http://dx.doi.org/10.1155/2018/3625139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158949PMC
September 2018
10 Reads

Haploidentical Stem Cell Transplantation: A Gateway to Infrequent Availability of HLA-Matched Related Donors.

Case Rep Med 2018 10;2018:2573657. Epub 2018 Sep 10.

Department of Medicine, Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA.

Haploidentical stem cell transplantation provides a plausible alternative for the patients when a fully matched donor is unavailable. Historically, the decision of considering haploidentical transplant has remained elusive; however, with the recent advances, the consideration of haploidentical grafts as a treatment option has become more apparent for both allografting for diseases and engraftment failure. We are reporting here an anecdotal case of a successful haploidentical engraftment in a patient with the prior graft failure of an HLA-matched related donor. Read More

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https://www.hindawi.com/journals/crim/2018/2573657/
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http://dx.doi.org/10.1155/2018/2573657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151688PMC
September 2018
19 Reads

A Case Report of Sarcoidosis Mimicking Vertebral Metastasis.

Case Rep Med 2018 9;2018:5326324. Epub 2018 Sep 9.

Department of Internal Medicine, Virginia Commonwealth University Health Systems, Richmond, VA, USA.

A 35-year-old African American male, previously healthy, presented with lower back and bilateral lower extremity pain associated with intermitted night sweats and weight loss. Imaging was concerning diffuse vertebral metastatic lesions. He underwent extensive workup to evaluate for metastatic disease. Read More

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http://dx.doi.org/10.1155/2018/5326324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151222PMC
September 2018
1 Read

Mitral Valve Endocarditis due to .

Case Rep Med 2018 4;2018:8613948. Epub 2018 Sep 4.

University Hospital, Department of Cardiology and Cardiovascular Medicine, Eberhard Karls University Tuebingen, 72076 Tuebingen, Germany.

species are Gram-positive, facultative anaerobic, rod-shaped bacteria. They belong to the lactic acid bacteria group and are also known as a usual part of the normal flora of the gastrointestinal tract as well as of the urinary and genital tracts. They are an infrequent human pathogen but can induce several infections such as bacteremia and infectious endocarditis. Read More

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http://dx.doi.org/10.1155/2018/8613948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142765PMC
September 2018
12 Reads