3,233,087 results match your criteria Case Reports in Medicine [Journal]


[Innovative New Evacuation Concept with Emergency Mattresses].

Z Orthop Unfall 2018 Dec 14;156(6):723-724. Epub 2018 Dec 14.

Sicherheitsmanagement, Klinikverbund Südwest GmbH, Sindelfingen.

Indication: In-hospital patients with limited mobility are extremely vulnerable in cases of emergency or fire. In the past, several large fires in multi-story hospitals have resulted in deaths.

Methods: For this reason, we have developed an evacuation mattress that incorporates the functions of an evacuation towel with the comfort of a normal mattress. Read More

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December 2018
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[Megaimplants of the Proximal Femur: Current Concepts].

Z Orthop Unfall 2018 Dec 14;156(6):685-691. Epub 2018 Dec 14.

Klinik und Poliklinik für Orthopädie und Sportorthopädie, Klinikum rechts der Isar, Technische Universität München.

In addition to their outstanding significance in the field of tumor orthopaedics, megaprostheses are becoming increasingly important for revision arthroplasty. Despite their wide application, the reported complication and failure rates remain high. The analysis of failure mechanisms roughly allows a breakdown into mechanical and non-mechanical causes; soft-tissue failure, loosening and periprosthetic infection play outstanding roles. Read More

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December 2018
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Association of Antenatal Depression with Clinical Subtypes of Preterm Birth.

Am J Perinatol 2018 Dec 14. Epub 2018 Dec 14.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, Massachusetts.

Objective:  To estimate the association between antenatal depression and spontaneous preterm birth (SPTB) relative to medically indicated preterm birth (MPTB).

Study Design:  This was a secondary analysis of a nested case-control study of preterm birth (PTB). The exposure was a clinical diagnosis of antenatal depression. Read More

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December 2018
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Partial Costotransversectomy and Corpectomy for Thoracic Spinal Metastatic Disease: Operative Technique and Nuances: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2018 Dec 14. Epub 2018 Dec 14.

Department of Neurologic Surgery, Mayo Clinic Florida, Jacksonville, Florida.

We describe the operative approach and management for thoracic metastatic disease in a 78-yr-old man with worsening mechanical lower back and left-sided thoracic radicular pain. Imaging of the thoracic spine revealed an osteolytic T11 mass with destruction of the left T11 pedicle and transverse process. Biopsy confirmed spinal metastasis from the liver. Read More

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December 2018

Clipping of Basilar Perforator Pure Arterial Malformation Aneurysm: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2018 Dec 14. Epub 2018 Dec 14.

University of Miami, Department of Neurosurgery, Miami, Florida.

Pure arterial malformations are rarely-encountered intracranial lesions, often mistaken for arteriovenous malformations. A minority of these lesions may harbor associated aneurysms. In a recent series of 12 patients with pure arterial malformations, 3 patients had associated aneurysms. Read More

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December 2018

Two Extraordinary Sellar Neuronal Tumors: Literature Review and Comparison of Clinicopathologic Features.

Am J Clin Pathol 2018 Dec 14. Epub 2018 Dec 14.

Department of Pathology, Duke University Medical Center, Durham, NC.

Objectives: The list of tumors involving the pituitary gland has been expanded to include a variety of neuronal and paraneuronal tumors in the 2017 World Health Organization tumor classification of endocrine organs. All the entities included in this category are distinctly rare, with limited case reports in the literature.

Methods: We illustrate two extraordinary sellar tumors with neuronal differentiation: a sellar paraganglioma and a sellar neurocytoma, with thorough literature review and comparison of the clinicopathologic features of these entities. Read More

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December 2018

Just the Tip: Resection of a Narcotic Catheter-Tip Granuloma: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2018 Dec 14. Epub 2018 Dec 14.

Department of Neurosurgery, University of Miami, Jackson Memorial Hospital, Miami, Florida.

The catheter tip "granuloma" is a rare inflammatory mass that forms in about 3% of patients with an intradural catheter, most commonly from a morphine pump. It has also been seen with other narcotic pumps, narcotic-non-narcotic combinations, and baclofen pumps. Mass formation is associated with increased opioid dose and concentration. Read More

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December 2018

Appropriate use criteria adoption for PCI at an academic medical center.

Eur Heart J 2018 Dec;39(47):4136-4138

Division of Cardiovascular Medicine, Department of Medicine, Case Western Reserve University School of Medicine, 11100 Euclid Ave, Mailstop LKS 5038, Cleveland, Ohio, Phone: (216) 844-7760, Fax: (216) 844-8954.

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December 2018

Catheter ablation of a right epicardial accessory pathway via the small cardiac vein: Two case reports: Small cardiac vein-related accessory pathway.

J Electrocardiol 2018 Dec 4;52:106-108. Epub 2018 Dec 4.

Cardiovascular Division, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

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December 2018

Two distinct mechanisms of selection in working memory: Additive last-item and retro-cue benefits.

Cognition 2018 Dec 11;183:282-302. Epub 2018 Dec 11.

University of Zurich, Switzerland. Electronic address:

In working memory research, individual items are sometimes said to be in the "focus of attention". According to one view, this occurs for the last item in a sequentially presented list (last-item benefit). According to a second view, this occurs when items are externally cued during the retention interval (retro-cue benefit). Read More

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December 2018

Odorous compounds sources and transport from a swine deep-pit finishing operation: A case study.

J Environ Manage 2018 Dec 11;233:12-23. Epub 2018 Dec 11.

USDA Agricultural Research Service, National Laboratory for Agriculture and the Environment, 1015 N. University Boulevard, Ames, IA, 50011, United States.

Odor emissions from swine finishing operations are an air quality issue that affects residents at the local level. A study was conducted at a commercial swine deep-pit finishing operation in central Iowa to monitor odorous compounds emitted and transported offsite. Gaseous compounds were sampled using either sorbent tubes or canisters with GC/MS analysis, and particulates matter (PM) were sampled with high volume samplers and thermally extracted onto sorbent tubes for GC/MS analysis. Read More

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December 2018

Can catchment-scale urban stormwater management measures benefit the stream hydraulic environment?

J Environ Manage 2018 Dec 11;233:1-11. Epub 2018 Dec 11.

Waterway Ecosystem Research Group, School of Ecosystem and Forest Science, The University of Melbourne, Burnley, Victoria, 3121, Australia.

The potential for catchment-scale stormwater control measures (SCMs) to mitigate the impact of stormwater runoff issues and excess stormwater volume is increasingly recognised. There is, however, limited understanding about their potential in reducing in-channel disturbance and improving hydraulic conditions for stream ecosystem benefits. This study investigates the benefits that SCM application in a catchment have on in-stream hydraulics. Read More

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December 2018

Promoting opioid overdose prevention and recovery: An exploratory study of an innovative intervention model to address opioid abuse.

Int J Drug Policy 2018 Dec 11;64:21-29. Epub 2018 Dec 11.

NJ Division of Mental Health and Addiction Services, Office of Planning, Research, Evaluation and Prevention, 222 South Warren Street, Trenton, NJ 08625-0700, United States. Electronic address:

Background: Fatal opioid overdose is a national public health concern in the United States and a critical problem confronting New Jersey's addiction treatment system. New Jersey developed an innovative program, the Opioid Overdose Recovery Program (OORP), to address the epidemic and the issue of low treatment admissions following a non-fatal overdose. The OORP utilizes an intervention model with peer recovery specialists (RSs) and patient navigators (PNs) to engage individuals within emergency departments (EDs) immediately following an opioid overdose reversal. Read More

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December 2018

When is a "cryptic" species not a cryptic species: A consideration from the Holarctic micro-landsnail genus Euconulus (Gastropoda: Stylommatophora).

Mol Phylogenet Evol 2018 Dec 11. Epub 2018 Dec 11.

Department of Botany and Zoology, Masaryk University, Kotlářská 2, CZ-61137, Brno, Czechia. Electronic address:

Naive use of molecular data may lead to ambiguous conclusions, especially within the context of "cryptic" species. Here, we integrated molecular and morphometric data to evaluate phylogenetic relationships in the widespread terrestrial micro-snail genus, Euconulus. We analyzed mitochondrial (16S + COII) and nuclear (ITS1 + ITS2) sequence across 94 populations from Europe, Asia and North America within the nominate species E. Read More

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December 2018

Integrating multilocus DNA data and 3D geometric morphometrics to elucidate species boundaries in the case of Pyrenaearia (Pulmonata: Hygromiidae).

Mol Phylogenet Evol 2018 Dec 11. Epub 2018 Dec 11.

Department of Zoology and Animal Cell Biology, Faculty of Pharmacy, University of the Basque Country, EHU/UPV, Paseo de la Universidad 7, 01006 Vitoria-Gasteiz, Araba, Spain; Biodiversity Research Group CIEA Lucio Lascaray, Avda. Miguel de Unamuno 3, 01006, Araba, Spain. Electronic address:

To accurately delimit species the use of multiple character types is essential as all speciation processes are not equally reflected in different data (e.g. morphological, molecular or ecological characters). Read More

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December 2018

International priorities for home care education, research, practice, and management: Qualitative content analysis.

Nurse Educ Today 2018 Dec 7;73:83-87. Epub 2018 Dec 7.

Case Western Reserve University, United States of America. Electronic address:

Background: Despite growing demand for home care nursing, there is a growing home care workforce shortage, due in part to hospital-centric nursing curricula that lead students to undervalue of home care and community practice setting (Van Iersel et al., 2018a, 2018b).

Objectives: Articulate an international vision for the future of home care education, research, practice, and management shared by experienced home care nurses working in leadership roles. Read More

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December 2018

Linking biodiversity to ecosystem services supply: Patterns across aquatic ecosystems.

Sci Total Environ 2018 Dec 3;657:517-534. Epub 2018 Dec 3.

Department of Biology & CESAM, University of Aveiro, Campus de Santiago, 3810-193 Aveiro, Portugal.

Global initiatives have been increasingly focusing on mainstreaming the values of biodiversity and ecosystem services into decision-making at all levels. Due to the accelerated rate at which biodiversity is declining and its consequences for the functioning of ecosystems and subsequently, the services they provide, there is need to develop comprehensive assessments of the services and the benefits nature delivers to society. Based on expert evaluation, we identified relevant flow linkages in the supply-side of the socio-ecological system, i. Read More

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December 2018
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Integrated chemical exposure assessment of coastal green turtle foraging grounds on the Great Barrier Reef.

Sci Total Environ 2018 Nov 22;657:401-409. Epub 2018 Nov 22.

Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, 20 Cornwall St, Woolloongabba, Qld 4102, Australia.

The Great Barrier Reef receives run-off from 424,000 km catchment area across coastal Queensland, incorporating diffuse agricultural run-off, and run-off point sources of land-based chemical pollutants from urban and industrial development. Marine biota, such as green turtles (Chelonia mydas), are exposed to these diverse chemical mixtures in their natural environments, and the long term effects on turtle and ecosystem health remain unknown. This study was part of a larger multi-disciplinary project characterising anthropogenic chemical exposures from the marine environment and turtle health. Read More

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November 2018

When "thirsty" means "less able to activate the signalling wave trigged by a pulse of ozone": A case of study in two Mediterranean deciduous oak species with different drought sensitivity.

Sci Total Environ 2018 Dec 4;657:379-390. Epub 2018 Dec 4.

Department of Agriculture, Food and Environment, University of Pisa, Via del Borghetto 80, Pisa 56124, Italy; CIRSEC, Centre for Climatic Change Impact, University of Pisa, Via del Borghetto 80, Pisa 56124, Italy.

There is a lack of knowledge about the possibility that plants facing abiotic stressors, such as drought, have an altered perception of a pulse of O and incur in alterations of their signalling network. This poses some concerns as to whether defensive strategy to cope episodic O peaks in healthy plants may fail under stress. In this study, a set of saplings of two Mediterranean deciduous species, Quercus cerris and Q. Read More

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December 2018

Role of the androgen receptor gene CAG repeat polymorphism on the sequence of pubertal events and adiposity in girls with high dehydroepiandrosterone sulfate.

J Pediatr Adolesc Gynecol 2018 Dec 11. Epub 2018 Dec 11.

Institute of Maternal and Child Research, School of Medicine, University of Chile, Santiago, Chile. Electronic address:

Study Objective: The Androgen Receptor (AR) harbors a variable repeat of a variable number of glutamine residues [(CAG)n] which seems to affect inversely AR transcriptional activity. We assessed whether (CAG)n affect the sequence of the androgen-sensitive pubertal events and body composition in prepubertal girls.

Design: and participants: Nested case-control study within the Growth and Obesity Cohort Study of 1196 low-middle income children (≈50% girls) from Santiago, Chile. Read More

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December 2018
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Expanding the Molecular Characterization of Thoracic Inflammatory Myofibroblastic Tumors beyond ALK gene rearrangements.

J Thorac Oncol 2018 Dec 11. Epub 2018 Dec 11.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address:

Background: Half of inflammatory myofibroblastic tumors (IMTs) regardless of anatomic location harbor ALK gene rearrangements and overexpress ALK protein. The wide application of next generation sequencing (NGS) and the clinical benefit to tyrosine kinase inhibitors have opened new opportunities for investigation of ALK-negative IMT.

Design: In this study we investigate a series of pediatric and adult thoracic IMT for abnormalities in a wide spectrum of actionable kinases, by applying a variety of molecular and NGS techniques, including FISH, targeted RNA sequencing and NanoString. Read More

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December 2018
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A two-thresholds policy to interrupt transmission of West Nile Virus to birds.

J Theor Biol 2018 Dec 11. Epub 2018 Dec 11.

Department of Mathematics & Statistics, York University, Toronto, ON, M3J 1P3, Canada.

This paper proposes a model of West Nile Virus (WNV) including threshold control policies concerning the culling of mosquitoes and birds under different conditions. Two thresholds are introduced to estimate whether and which control strategy should be implemented. For each mosquito threshold level [Formula: see text] the dynamical behaviour of the proposed non-smooth system is investigated as the bird threshold level [Formula: see text] varies, focusing on the existence of sliding domains, the existence of pseudo-equilibria, real or virtual of the endemic equilibria, global stability of these steady states, and the most interesting case of the occurrence of a novel globally asymptotically stable pseudo-attractor. Read More

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December 2018
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Reducing the Complexity of Mathematical Models for the Plant Circadian Clock by Distributed Delays.

J Theor Biol 2018 Dec 11. Epub 2018 Dec 11.

Sainsbury Laboratory, University of Cambridge, Bateman Street, Cambridge, CB2 1LR, UK. Electronic address:

A major bottleneck in the modelling of biological networks is the parameter explosion problem - the exponential increase in the number of parameters that need to be optimised to data as the size of the model increases. Here, we address this problem in the context of the plant circadian clock by applying the method of distributed delays. We show that using this approach, the system architecture can be simplified efficiently - reducing the number of parameters - whilst still preserving the core mechanistic dynamics of the gene regulatory network. Read More

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December 2018

Ribosomal protein eL42 contributes to the catalytic activity of the yeast ribosome at the elongation step of translation.

Biochimie 2018 Dec 11. Epub 2018 Dec 11.

Sorbonne Université, Campus Pierre et Marie Curie, Laboratoire "Enzymologie de l'ARN", SU-UR6; (Bâtiment B); Case courrier 60 - 4, Place Jussieu, F-75252, Paris Cedex 05, France.

The GGQ minidomain of the ribosomal protein eL42 was previously shown to contact the CCA-arm of P-site bound tRNA in human ribosome, indicating a possible involvement of the protein in the catalytic activity. Here, using Schizosaccharomyces pombe (S. pombe) cells, we demonstrate that the GGQ minidomain and neighboring region of eL42 is critical for the ribosomal function. Read More

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December 2018

Degradation Rate Observations as a Function of Drug Load in Solid State Drug Products.

J Pharm Sci 2018 Dec 11. Epub 2018 Dec 11.

Analytical Research & Development, Pfizer Inc, Sandwich, UK.

Degradation rates of solid state drug products generally increase as the drug load decreases. A model for quantifying this effect based on surface area ratios is proposed here. This model relates the degradation rate to an estimate of the proportion of drug substance in contact with the excipient, and that the drug substance in contact with excipients degrades more quickly. Read More

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December 2018

Fracture of a Transcatheter Atrial Septal Defect Occluder Device Causing Mitral Valve Perforation.

Ann Thorac Surg 2018 Dec 11. Epub 2018 Dec 11.

Department of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland; Department of Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland.

Transcatheter atrial septal defect (ASD) device closure has gained increasing popularity over the past decades due to shorter hospital stay and the absence of skin scars. However, concern about the seriousness of device-related complications is accumulating. We report a case of device fracture in a young asymptomatic woman almost 4 years after percutaneous secundum ASD closure, resulting in mitral valve perforation. Read More

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December 2018
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Clinicopathological and molecular analysis of multinodular and vacuolating neuronal tumors of the cerebrum.

Hum Pathol 2018 Dec 11. Epub 2018 Dec 11.

Department of Pathology, Seoul National University Hospital and Seoul National University College of Medicine, Seoul, Republic of Korea; Institute of Neuroscience, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

Multinodular and vacuolating neuronal tumor (MVNT) of the cerebrum is a recently recognized rare neuronal tumor, and its pathogenesis is unclear. We analyzed 7 cases of histologically typical MVNT: six were adults [mean age: 43.0years (range: 23-56)] and one was a child (10-year-old). Read More

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December 2018

Counterfactual Thinking, Causation, and Covariation in Mock Juror Assessments of Negligence: Twenty-Five Years Later.

Authors:
Jason A Cantone

Psychol Rep 2018 Dec 14:33294118816945. Epub 2018 Dec 14.

George Mason University, Fairfax, VA, USA.

In the past three decades, researchers have examined counterfactual thinking and causation in decision making. However, little work has applied these findings to trial settings. The present research examined two conflicting theories regarding counterfactual thinking and causation to elaborate on earlier work examining counterfactual thinking in negligence law cases. Read More

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December 2018

Atypical Prenatal Ultrasound Presentation and Neuropathological Findings in a Neonate With Alpha Thalassemia Major: A Case Report.

Pediatr Dev Pathol 2018 Dec 14:1093526618817655. Epub 2018 Dec 14.

1 Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Canada.

Alpha thalassemia major is a hemoglobinopathy caused by the inactivation or deletion of all 4 α-globin alleles. We describe a case of α-thalassemia major with atypical ultrasound and neuropathological findings. The mother had her first prenatal visit at 27 4/7 gestational weeks. Read More

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December 2018

The Shocking Time It Takes to Initiate ECT: A Clinically and Legally Complicated Case of Catatonia.

Prim Care Companion CNS Disord 2018 Dec 13;20(6). Epub 2018 Dec 13.

Department of Psychiatry, Henry Ford Behavioral Health Services, Henry Ford Health System, Detroit, Michigan, USA.

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December 2018

Internet-based cognitive and behavioural therapies for post-traumatic stress disorder (PTSD) in adults.

Cochrane Database Syst Rev 2018 Dec 14;12:CD011710. Epub 2018 Dec 14.

Division of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Hadyn Ellis Building, Maindy Road, Cardiff, UK, CF24 4HQ.

Background: Therapist-delivered trauma-focused psychological therapies are an effective treatment for post-traumatic stress disorder (PTSD). These have become the accepted first-line treatments for the disorder. Despite the established evidence-base for these therapies, they are not always widely available or accessible. Read More

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December 2018

A review of lifestyle, metabolic risk factors and blood-based biomarkers for early diagnosis of pancreatic ductal adenocarcinoma.

J Gastroenterol Hepatol 2018 Dec 14. Epub 2018 Dec 14.

Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health|, University of Oxford, Oxford, UK.

We aimed to review the epidemiologic literature examining lifestyle, metabolic risk factors, and blood-based biomarkers including multi-omics (genomics, proteomics, and metabolomics) and to discuss how these predictive markers can inform early diagnosis of pancreatic ductal adenocarcinoma (PDAC). A search of the PubMed database was conducted in June 2018 to review epidemiologic studies of (1) lifestyle and metabolic risk factors for PDAC, genome-wide association studies (GWAS), and risk prediction models incorporating these factors and (2) blood-based biomarkers for PDAC (conventional diagnostic markers, metabolomics, and proteomics). Prospective cohort studies have reported at least twenty possible risk factors for PDAC, including smoking, heavy alcohol drinking, adiposity, diabetes, and pancreatitis, but the relative risks (RR) and population attributable fractions of individual risk factors are small (mostly <10%). Read More

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December 2018
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Platelet-Rich Fibrin as a Grafting Material in Periapical Surgery: A Case Series.

Int J Periodontics Restorative Dent 2018 Dec 14. Epub 2018 Dec 14.

Positive effects of platelet-rich fibrin (PRF) on soft tissue healing are well documented, but its role in hard-tissue healing remains contested. The present case series documents the use of PRF as the sole grafting material in periapical bone defects. PRF was prepared and condensed into the bone defects after debridement. Read More

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December 2018

Musculoskeletal injuries and absenteeism among healthcare professionals-ICD-10 characterization.

PLoS One 2018 14;13(12):e0207837. Epub 2018 Dec 14.

Department of Occupational Health, Centro Hospitalar Universitário São João, Porto, Portugal.

Introduction: Healthcare workers account for 10% of the EU's total workforce, with a significant proportion of those employed in hospitals. Musculoskeletal injuries are the predominant group of injuries in healthcare professionals due to the physical demands of their work, such as the mobilization and positioning of the dependent patients. The management of this type of problem should take into account direct and indirect costs, such as periods of incapacity for work due to illness, hiring and training of new employees during periods of absence, reduced levels of productivity and the effects on production and quality of work. Read More

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December 2018
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Expression of CD25 fluctuates in the leukemia-initiating cell population of CD25-positive AML.

PLoS One 2018 14;13(12):e0209295. Epub 2018 Dec 14.

Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu, Mie, Japan.

CD25 is expressed on leukemic cells in 10-20% cases of acute myeloid leukemia (AML), and its expression is associated with poor prognosis. We reevaluated the relationship between CD25 expression and the leukemia-initiating cell (LIC) properties of AML using a patient-derived xenograft model. We divided lineage marker-negative (Lin-) CD34+CD38- or Lin-CD34+ cells from CD25-positive AML into CD25-positive and -negative populations, and then transplanted each population into NOD. Read More

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December 2018
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Economic impact of dengue in Mexico considering reported cases for 2012 to 2016.

PLoS Negl Trop Dis 2018 Dec 14;12(12):e0006938. Epub 2018 Dec 14.

Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.

Background: Given that dengue disease is growing and may progress to dengue hemorrhagic fever (DHF), data on economic cost and disease burden are important. However, data for Mexico are limited.

Methodology/principal Findings: Burden of dengue fever (DF) and DHF in Mexico was assessed using official databases for epidemiological information, disabilities weights from Shepard et al, the reported number of cases and deaths, and costs. Read More

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December 2018

Toll-like receptor chaperone HSP90B1 and the immune response to Mycobacteria.

PLoS One 2018 14;13(12):e0208940. Epub 2018 Dec 14.

University of Washington, Seattle, WA, United States of America.

Rationale: HSP90B1, also known as gp96, is a chaperone for multiple Toll-like receptors (TLRs) and is necessary for TLR-mediated inflammatory responses in murine myeloid cells. The molecule is also expressed in T-cells though its specific role is unknown. We hypothesized that human HSP90B1 regulates monocyte and T-cell responses to Mycobacterium tuberculosis (Mtb) and bacilli Calmette-Guerin (BCG) and that its variants are associated with susceptibility to TB disease. Read More

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December 2018

Predictors of malaria Rapid Diagnostic Tests' utilisation among healthcare workers in Zamfara State.

PLoS One 2018 14;13(12):e0200856. Epub 2018 Dec 14.

Nigeria Field Epidemiology and Laboratory Training Programme, Abuja, Nigeria.

Introduction: Early diagnosis and prompt and effective treatment is one of the pillars of malaria control. Malaria case management guidelines recommend diagnostic testing before treatment using malaria Rapid Diagnostic Test (mRDT) or microscopy and this was adopted in Nigeria in 2010. However, despite the deployment of mRDT, the use of mRDTs by health workers varies by settings. Read More

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December 2018

Interventions to treat cutaneous leishmaniasis in children: A systematic review.

PLoS Negl Trop Dis 2018 Dec 14;12(12):e0006986. Epub 2018 Dec 14.

Unidad Clínica de Leishmaniasis, Centro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia.

Background: Case management in children with cutaneous leishmaniasis (CL) is mainly based on studies performed in adults. We aimed to determine the efficacy and harms of interventions to treat CL in children.

Methods: We conducted a systematic review of clinical trials and cohort studies, assessing treatments of CL in children (≤12 years old). Read More

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December 2018
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Which Cut-offs for Secondary V[Combining Dot Above]O2max Criteria Are Robust to Diurnal Variations?

Med Sci Sports Exerc 2018 Dec 13. Epub 2018 Dec 13.

Department of Sport, Exercise and Health, Faculty of Medicine, University of Basel, Basel, Switzerland.

Purpose: The aim was to determine the minimum secondary exhaustion criteria cut-offs (i.e. max respiratory exchange ratio [RERmax], max heart rate [HRmax], max rating of perceived exertion [RPEmax], and max blood lactate concentration [BLmax]) necessary to determine maximum oxygen uptake (VO2max) during cardiopulmonary exercise tests (CPET), by balancing type I and type II errors. Read More

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December 2018

Effects of Intimate Partner Violence and Home Environment on Child Language Development in the First 3 Years of Life.

J Dev Behav Pediatr 2018 Dec 13. Epub 2018 Dec 13.

Department of Pediatrics, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH.

Objective: Intimate partner violence (IPV) can adversely affect children's cognitive development, but links between IPV exposure and language development in the earliest years of life remain unknown. The present study examined the effects of IPV and the quality of the home environment on children's language development at age 3 years.

Methods: In a prospective, 5-panel, longitudinal study of 79 mother-child dyads assessed prenatally to age 3 years, we examined standardized measures of receptive and expressive language development at age 3 years. Read More

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December 2018
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A Prospective Comparative Study Between Subcuticular and Sutureless Technique of Skin Closure Following External Dacryocystorhinostomy.

Ophthalmic Plast Reconstr Surg 2018 Dec 7. Epub 2018 Dec 7.

Orbit Oculoplasty Reconstructive and Aesthetic Services, Aditya Birla Sankara Nethralaya, Kolkata, India.

Purpose: To compare the cosmetic outcome of the surgical scar of external dacryocystorhinostomy by the subcuticular versus sutureless technique.

Methods: This was a prospective interventional randomized control study conducted at tertiary level hospital. Fifty patients of primary-acquired nasolacrimal duct obstruction were included in this study. Read More

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December 2018
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Orbital Floor and Rim Reconstruction With a Titanium Orbital Implant and Acellular Dermis.

Ophthalmic Plast Reconstr Surg 2018 Dec 7. Epub 2018 Dec 7.

Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas, U.S.A.

Reconstruction of the orbital rim and floor following tumor excision is traditionally performed with bone grafts, vascularized grafts, or free flaps. The authors describe a case of an osteosarcoma of the maxillary sinus and a second case of an ossifying fibroma of the orbital floor, both of which required reconstruction of the orbital floor and rim. In both of these cases, reconstruction of the orbital floor and rim was performed with a titanium implant whose anterior portion was bent inferiorly to recreate the orbital rim. Read More

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December 2018

Bony Orbital Volume Expansion in Thyroid Eye Disease.

Ophthalmic Plast Reconstr Surg 2018 Dec 7. Epub 2018 Dec 7.

Doheny Eye Institute, Division of Orbital and Ophthalmic Plastic Surgery, University of California-Los Angeles, Los Angeles, California, U.S.A.

Purpose: To quantify changes to the bony orbital volume (BOV) in patients with thyroid eye disease (TED) relative to normal controls.

Methods: In this case-control study, all patients affected with TED seen over a 2-year period were screened for study entry. Eligible participants were adults with clinical evidence of TED and CT scans of their orbits obtained during the course of their routine care. Read More

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December 2018
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Alternatives for Pediatric Anticoagulation: The Case for Bivalirudin.

Authors:
Naveen Nathan

Anesth Analg 2019 Jan;128(1)

Northwestern University Feinberg School of Medicine

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January 2019

Single Suture Synostosis and Isolated Cleft Palate in Non-Apert Syndrome Patients.

J Craniofac Surg 2018 Dec 13. Epub 2018 Dec 13.

Birmingham Children's Hospital, Birmingham, UK.

Introduction: Single suture craniosynostosis (SSC) and isolated cleft palate (ICP) in non-Apert syndrome patients rarely occur together. Management includes airway optimization, timing surgery appropriately, and assessing both cranial vault aesthetics and speech outcomes. The aim of this study was to compare treatment pathways and outcomes in patients with both conditions to standard treatment for these conditions in isolation. Read More

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December 2018

Autologous Fat Injection for the Correction of Facial Depression Resulting From Silent Sinus Syndrome.

J Craniofac Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Otolaryngology-Head and Neck Surgery, Gil Medical Center, Gachon University School of Medicine, Incheon, Republic of Korea.

The case of a 59-year-old woman who underwent endoscopic sinus surgery for right maxillary sinusitis 5 years before visiting our otorhinolaryngologic department complaining of right-sided facial depression was described in this study. Computed tomography (CT) scans revealed right facial depression and retraction of the orbital floor due to a hypoplastic right maxillary sinus. Symptoms and CT findings corresponded with silent sinus syndrome. Read More

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December 2018

Third Molar Eruption and Hardware Fungal Infection Following Treatment of Mandibular Angle Fracture.

J Craniofac Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Plastic Surgery, University of Virginia Health System.

Appropriate management of lower 3rd molars is crucial to successful treatment of mandibular angle fractures. A unique case of a patient who presented for initial management of a left mandibular angle fracture with an unerupted lower 3rd molar was discussed in this study. After treatment with open reduction and internal fixation of the fracture, the lower 3rd molar erupted and the patient subsequently developed fungal osteomyelitis and hardware failure. Read More

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December 2018
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