Search Our Scientific Publications & Authors

Cancer Chemother Pharmacol 2018 Dec 10. Epub 2018 Dec 10.

Medical Oncology Department, Abderrahmane Mami Hospital, Rue de l'Hopital, Ariana, Tunisia.

The original version of this article unfortunately contained a mistake. The given name and family name were swapped. Read More

Plast Reconstr Surg Glob Open 2018 Oct 2;6(10):e1840. Epub 2018 Oct 2.

Department of Plastic Surgery, Yale University, Cedar Street, New Haven, Conn.

Background: Telemedicine is a rapidly growing tool since its invention in the 1950s. Recently, it has expanded to the field of plastic surgery. In the Connecticut VA System, there is 1 plastic surgeon at a central location for the state of Connecticut and southern Massachusetts. Read More

Case Rep Orthop 2018 8;2018:7430297. Epub 2018 Nov 8.

Department of Orthopaedic Surgery, New York-Presbyterian Hospital, New York, USA.

"Floating elbow" injuries of the arm traditionally represent a combination of humeral shaft and forearm fractures which require anatomic rigid open reduction and internal fixation of all fractures to allow for early range of motion exercises of the elbow. There are published variants of the floating elbow injury which include ipsilateral diaphyseal humeral fracture, proximal ulna fracture with proximal radioulnar joint disruption, and ipsilateral diaphyseal humeral fracture with elbow dislocation and both bones forearm fracture. We present the case of a 21-year-old woman whose left arm became caught between the side of a waterslide and adjacent rocks at a park. Read More

Indian J Orthop 2018 Nov-Dec;52(6):596-601

Department of Orthopaedic Surgery, Korea University Anam Hospital, Seoul, Korea.

Background: Tears of the triangular fibrocartilage complex (TFCC) can result in instability of the distal radioulnar joint (DRUJ) and ulnar-sided wrist pain. This study evaluates clinical results of arthroscopic transosseous repair for both proximal and distal components of TFCC tear with DRUJ instability.

Materials And Methods: Ten patients who underwent both proximal component and distal component of TFCC repair were retrospectively reviewed. Read More

Plast Reconstr Surg 2018 Nov 26. Epub 2018 Nov 26.

Background: Economic conditions affect surgical volumes, particularly for elective procedures. In this study, we aimed to identify the effects of the 2008 US economic downturn on hand surgery volumes to guide surgeons and managers when facing future economic crises.

Methods: We used the California State Ambulatory Surgery and Services Databases from January 2005 to December 2011, which includes the entire period of the Great Recession (December 2007 to June 2009). Read More

Hand Surg Rehabil 2018 Dec 5. Epub 2018 Dec 5.

Service de traumatologie orthopédie I, Hôpital militaire d'instruction Mohamed V, Hay Ryad (avenue des FAR), 10000 Rabat, Morocco.

Carpal tunnel syndrome (CTS) is the most frequent among entrapment neuropathies. The usual etiology is idiopathic, but can be caused by space-occupying lesions, a relatively rare condition. This condition becomes exceptional when the space-occupying lesion corresponds to a rare tumor whose location is atypical. Read More

Joint Bone Spine 2018 Dec 6. Epub 2018 Dec 6.

Rheumatology Department, Norfolk & Norwich University Hospital, Colney Lane, Norwich, NR4 7UY. UK.

Am J Trop Med Hyg 2018 Dec 10. Epub 2018 Dec 10.

Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

From April to September 2017, Bangladesh experienced a huge outbreak of acute Chikungunya virus infection in Dhaka. This series describes the clinical and laboratory features of a large number of cases (690; 399 confirmed and 291 probable) suffered during that period. This observational study was carried out at Dhaka Medical College Hospital, Bangladesh. Read More

Curr Rheumatol Rev 2018 Dec 10. Epub 2018 Dec 10.

Department of Orthopedic Surgery, SUNY Upstate Medical University, Syracuse, New York. United States.

Background: Scapholunate interosseous ligament (SLIL) injury following a fall on an outstretched hand may lead to carpal instability and in some cases require long term rehabilitation following repair. Rehabilitation, especially in athletes, may include pushups, but little is known as to what type of pushup may be safer.

Objective: To determine biomechanical differences between two pushup position (neutral or extended). Read More

Sports Biomech 2018 Dec 11:1-16. Epub 2018 Dec 11.

d Department of Biomedical Engineering , National Cheng Kung University , Tainan , Taiwan.

This study examined the morphologic changes of the ulnar nerve in different elbow positions by ultrasonography and the effects of fatigue on forearm muscle control during overhand movements. We enrolled 12 tennis players who performed flat serves and 15 baseball pitchers who performed fastball pitching. The motion capture was conducted with 14 reflective markers attached on anatomic landmarks of the participant for tennis serve and baseball pitching data collection. Read More

Cochrane Database Syst Rev 2018 Dec 2;12:CD011215. Epub 2018 Dec 2.

School of Korean Medicine, Pusan National University, Beom-eu, Meulgeum, Yangsan, Korea, South, 626-870.

Background: Carpal tunnel syndrome (CTS) is a compressive neuropathic disorder at the level of the wrist. Acupuncture and other methods that stimulate acupuncture points, such as electroacupuncture, auricular acupuncture, laser acupuncture, moxibustion, and acupressure, are used in treating CTS. Acupuncture has been recommended as a potentially useful treatment for CTS, but its effectiveness remains uncertain. Read More

Curr Rheumatol Rev 2018 Dec 5. Epub 2018 Dec 5.

Department of Orthopedic Surgery, SUNY Upstate Medical University, Syracuse, NY. United States.

Morphology may provide the basis for the understanding of wrist mechanics. We used classification systems based on cadaver dissection of lunate and capitate types to evaluate a normal database of 70 wrist radiographs in 35 subjects looking for associations between bone shapes. Kappa statistics and a log-linear mixed -effects model with a random intercept were used. Read More

Clin Dysmorphol 2019 Jan;28(1):7-16

Greenwood Genetic Center, Greenwood, South Carolina.

Mucolipidosis-IIIγ (ML-IIIγ) is a recessively inherited slowly progressive skeletal dysplasia caused by mutations in GNPTG. We report the genetic and clinical findings in the largest cohort with ML-IIIγ so far: 18 affected individuals from 12 families including 12 patients from India, five from Turkey, and one from the USA. With consanguinity confirmed in eight of 12 families, molecular characterization showed that all affected patients had homozygous pathogenic GNPTG genotypes, underscoring the rarity of the disorder. Read More

Tech Hand Up Extrem Surg 2018 Nov 30. Epub 2018 Nov 30.

Christine M. Kleinert Institute, University of Louisville, Louisville, KY.

Arthritis of scaphotrapeziotrapezoid joint is common and can be seen in association with first carpal metacarpal (CMC) arthritis. Untreated scaphotrapeziotrapezoid arthritis may be a cause of residual pain after CMC arthroplasty. There are various treatment options described in the literature ranging from arthrodesis, resection arthroplasty, interpositional arthroplasty, and implant arthroplasty. Read More

Orthop Traumatol Surg Res 2018 Nov 29. Epub 2018 Nov 29.

Faculté de médecine de Tours, service d'orthopédie traumatologie, université François-Rabelais de Tours, CHRU de Trousseau, 1C, avenue de la République, 37170 Chambray-les-Tours, France.

Background: In patients with rheumatoid arthritis, the surgical treatment of wrist lesions relies on synovectomy combined with stabilisation and realignment of the carpal bones. The objective of this study was to evaluate the outcomes and define the indications of extensor carpi radialis longus (ECRL) transfer to the extensor carpi ulnaris (ECU) as described by Clayton and Ferlic.

Hypothesis: ECRL-to-ECU transfer combined with synovectomy can prevent the development and/or progression of rheumatoid deformities at the wrist. Read More

J Hand Surg Am 2018 Nov 28. Epub 2018 Nov 28.

Department of Orthopedics, VOICES Health Policy Research Center, Stanford University, Redwood City, CA; One Medical, San Francisco, CA.

Purpose: Carpal tunnel surgery is one of the most common procedures completed on the upper limb in the United States. There is currently no evidence-based high-value clinical care pathway to inform the management of carpal tunnel syndrome (CTS). We created an evidence-based care pathway and implemented a quality improvement initiative to evaluate its effect on patient time, quality, and cost in a tertiary care ambulatory surgery center. Read More

J Hand Surg Am 2018 Nov 27. Epub 2018 Nov 27.

Department of Orthopaedic Surgery, Penn State Hershey Medical Center, Hershey, PA.

Purpose: To compare the efficacy of opioid versus nonopioid analgesic regimens after elective, soft tissue hand surgery. We hypothesized that there would be no difference in patient-perceived pain relief between these 2 groups.

Methods: This prospective, randomized, double-blinded controlled trial included patients undergoing elective soft tissue hand procedures (carpal tunnel release, trigger finger release, first dorsal compartment release, or ganglion cyst excision). Read More

J Hand Surg Am 2018 Nov 27. Epub 2018 Nov 27.

Hand and Elbow Section, Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL.

Purpose: The aim of this study was to assess the treatment and complications of a distinct type of partial intra-articular distal radius fracture.

Methods: Seven patients treated by the senior author between 2008 and 2013 for a partial intra-articular distal radius fracture with isolated involvement of the volar lunate facet were included. All fragments had the distinctive shape of a triangular-base pyramid (tetrahedron) extending from the metaphysis distally. Read More

Hand (N Y) 2018 Dec 2:1558944718813721. Epub 2018 Dec 2.

3 Centro Universitário Serra dos Órgãos, Teresópolis, Brazil.

Background: The purpose of this study was to evaluate the safety and efficacy of ambulatory open surgical treatment for carpal tunnel syndrome with local anesthesia and without tourniquet ischemia, sedation by an anesthesiologist, or hospitalization.

Methods: A retrospective analysis of 60 consecutive cases performed during 1 year was conducted, excluding other compressive or noncompressive neuropathies. The criteria for treatment efficacy were improvements in symptoms and recurrence rates, and the safety criterion was the presence of complications. Read More

J Orthop Sports Phys Ther 2018 Nov 30:1-27. Epub 2018 Nov 30.

Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Universidad Rey Juan Carlos, Alcorcón, Spain.

Study Design: A randomized clinical trial.

Background: Carpal tunnel syndrome (CTS) results in substantial costs for the society and can be treated by either nonsurgical or surgical approaches.

Objective: To evaluate cost-effectiveness differences of manual physical therapy versus surgery in women with CTS. Read More

J Orthop Sports Phys Ther 2018 Nov 30:1-38. Epub 2018 Nov 30.

Sports Medicine Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH.

Study Design: Systematic review with meta-analysis.

Background: Needling has been shown to decrease pain in the short-term; however, its effects on muscle force production are unclear.

Objective: Evaluate the evidence regarding the comparative effects of needling on muscle force production. Read More

J Bone Joint Surg Am 2018 Dec;100(23):e148

Department of Orthopaedic Surgery (C.J.D. and C.A.G.), Division of Public Health Services, Department of Surgery (C.J.D.), and Division of General Medical Sciences (A.L.A. and J.M.D.), Washington University School of Medicine, St. Louis, Missouri.

Background: Overlapping surgery is attracting increased scrutiny. The American College of Surgeons states that the attending surgeon must be present for all critical portions of a surgical procedure; however, critical portions of surgical procedures are not defined. We hypothesized that a Delphi panel process would measure consensus on critical portions of 3 common hand surgical procedures. Read More

Musculoskelet Surg 2018 Dec 4. Epub 2018 Dec 4.

Department of Trauma and Handsurgery, Heinrich Heine University Hospital Duesseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany.

Background: Radial head arthroplasty represents a widely accepted treatment for elbow injuries with non-reconstructible radial head fractures. The aim of this retrospective multicenter study was to assess mid-term results of patients with clearly defined elbow injuries including type III fractures of the radial head according to Mason's classification type III after primary arthroplasty using a cemented bipolar design.

Materials And Methods: In 45 cases a primary cemented bipolar arthroplasty of the radial head was implanted for elbow injuries combined with an acute Mason type III radial head fracture. Read More

Med Arch 2018 Oct;72(4):253-256

Department of Orthopedics and Traumatology, Vito Fazzi Hospital, Lecce, Italy.

Introduction: The SNAC wrist (Scaphoid nonunion advanced collapse) is one of the complications following scaphoid fractures treated conservatively and one of the causes of wrist arthritis that the hand surgeon has to face most frequently. In these cases surgical management is usually warranted.

Materials And Methods: In the set time frame of 6 years we treated 15 SNAC wrist cases. Read More

J Hand Surg Eur Vol 2018 Dec 4:1753193418817172. Epub 2018 Dec 4.

Capio/CFR Hospital, Hellerup, Denmark.

I summarize my changing views and practices of arthroplasty in hand surgery over the past four decades. I recommend simple resection of the trapeziectomy for advanced arthritis of the first carpometacarpal joint, silicone implants for the metacarpophalangeal joints and the proximal interphalangeal joints, and the total wrist arthroplasty for advanced wrist arthritis and collapse. I also outline technical tips of these procedures. Read More

J Hand Surg Eur Vol 2018 Dec 4:1753193418815546. Epub 2018 Dec 4.

1 Department of Orthopaedic Surgery, Brigham and Women's Hospital, Boston, MA, USA.

The utility of routine preoperative electrodiagnostic studies for carpal tunnel syndrome is controversial. One argument in support of routine preoperative electrodiagnostic study is the acquisition of an objective baseline for comparison in cases of postoperative symptom persistence or recurrence. We identified 1141 patients who underwent carpal tunnel release in 1383 limbs at a tertiary care referral centre from July 2008 to June 2013. Read More

PLoS One 2018 4;13(12):e0207509. Epub 2018 Dec 4.

Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa, United States of America.

Importance: Carpal tunnel syndrome (CTS) is a common and debilitating condition that commonly affects postmenopausal women.

Objective: To determine the effect of menopausal hormone therapy (HT) in healthy postmenopausal women on CTS risk.

Design: We conducted a secondary analysis of the Women's Health Initiative's (WHI) HT trials linked to Medicare claims data. Read More

Turk J Pediatr 2018 ;60(3):344-347

Pediatric Rheumatology, Department of Pediatrics, Faculty of Medicine, Erciyes University, Kayseri, Turkey.

Gökay S, Kardaş F, Kendirci M, Sözeri B. Arthropathy-like findings and a carpal tunnel syndrome as the presenting features of Scheie syndrome: Three cases from the same family. Turk J Pediatr 2018; 60: 344-347. Read More

Medicine (Baltimore) 2018 Nov;97(48):e13229

Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

No surgical procedure perfectly treats advanced Kienböck disease. Although vascularized os pisiform transferring (VOPT) is one of the main therapeutic approaches, reports on long-term follow-up and case series for this technique are scarce.We collected postoperative results in 11 patients with advanced Kienböck disease who underwent VOPT between 1986 and 2001 in our Hospital. Read More

Hand (N Y) 2018 Nov 30:1558944718813669. Epub 2018 Nov 30.

1 NYU Langone Orthopedic Hospital, New York City, USA.

Background: Many patients treated for ulnar nerve compression at the elbow (UNE) are concomitantly treated for carpal tunnel syndrome (CTS). We sought to investigate the association between the conditions.

Methods: The Statewide Planning and Research Cooperative System (SPARCS) database was used to determine the number of patients with UNE concomitantly treated for CTS in New York State from 2003 to 2014. Read More

Cureus 2018 Sep 27;10(9):e3372. Epub 2018 Sep 27.

Internal Medicine, University at Buffalo / Sisters of Charity Hospital, Buffalo, USA.

Myelodysplastic syndrome (MDS) is often associated with autoimmune paraneoplastic manifestations. Seronegative arthritis is among one of them. Very rarely, pseudogout demonstrated as paraneoplastic autoimmune manifestations of MDS has been adumbrated so far. Read More

Hand (N Y) 2018 Nov 28:1558944718815253. Epub 2018 Nov 28.

2 Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.

Adv Ther 2018 Nov 27. Epub 2018 Nov 27.

University of Nevada at Reno, Reno, NV, USA.

Introduction: The objective of the study was to investigate the efficacy and safety of repeated incobotulinumtoxinA injections for the treatment of upper-limb post-stroke spasticity in adults.

Methods: Adults 18-80 years of age with post-stroke upper-limb spasticity who completed the 12-week randomized, double-blind, placebo-controlled main period (MP) of a phase 3 trial (NCT01392300) were eligible to enrol in the 36-week open-label extension period (OLEX). The OLEX included three treatment cycles at fixed 12-week injection intervals; subjects were injected with 400 U incobotulinumtoxinA into the affected upper limb. Read More

J Hand Microsurg 2018 Dec 20;10(3):150-154. Epub 2018 Mar 20.

Department of Orthopaedics, Maulana Azad Medical College, New Delhi, India.

Divergent trapezium-trapezoid fracture dislocation is a rare and complex injury. The authors present an unusual case of dislocation of the trapezium-trapezoid complex with scaphoid fracture. A 25-year-old man suffered a road traffic accident leading to complex carpal injury due to axial and rotation forces (steer wheel injury) on the left wrist. Read More

Zhonghua Zhong Liu Za Zhi 2018 Nov;40(11):869-871

Department of Orthopedics, Affiliated Hospital of Inner Mongolia University for The Nationalities, Tongliao 028000, China.

To evaluate the curative effect of proximal fibula graft of vascular anastomosis for giant cell tumor(GCT) of distal radius of bone. 38 patients with distal radius GCT were treated with proximal articular graft of anastomotic vessels. We evaluated the wrist joint function before and after surgery using wrist activity, visual analogue scale(VAS)pain score, grip recovery rate and Cooney scoring system. Read More

Zhonghua Yi Xue Za Zhi 2018 Nov;98(43):3490-3495

Institute of Digitized Medicine, Wenzhou Medical University, Zhejiang 325035, China.

To analyze the influence of simulation mouse use motion under different wrist forcing postures on median nerve, tendons and ligaments in the carpal tunnel. From June to November in 2017, a total of 49 healthy volunteers [aged from 18 to 27 years, 24 males (48 cases of hands) and 25 females (50 cases of hands)] were selected in the Institute of Digitized Medicine and First Affiliated Hospital of Wenzhou Medical University.Three hand postures of the volunteers were simultaneously and continuously measured by using LOGIQ E9 ultrasonic diagnostic apparatus and Zebris foot pressure distribution measurement system. Read More

J Fam Pract 2018 Nov;67(11):678-683

Department of Family Medicine, Uniformed Services University of Health Sciences, Bethesda, MD, USA.

Which devices do-and don't-have evidence to support their use when it comes to injuries like carpal tunnel syndrome, "tennis elbow," or an ankle sprain? Read on. Read More

J Digit Imaging 2018 Nov 26. Epub 2018 Nov 26.

Department of Radiology, Massachusetts General Hospital, 25 New Chardon Street Suite 400B, Boston, MA, 02114, USA.

Despite the well-established impact of sex and sex hormones on bone structure and density, there has been limited description of sexual dimorphism in the hand and wrist in the literature. We developed a deep convolutional neural network (CNN) model to predict sex based on hand radiographs of children and adults aged between 5 and 70 years. Of the 1531 radiographs tested, the algorithm predicted sex correctly in 95. Read More

Hand Surg Rehabil 2018 Nov 21. Epub 2018 Nov 21.

Department of hand surgery, SOS main, CCOM, university hospital of Strasbourg, FMTS, University of Strasbourg, Icube CNRS 7357, 10, avenue Baumann, 67400 Illkirch, France. Electronic address:

The aim of our study was to demonstrate the benefits of combining the Canaletto® implant with carboxymethylcellulose/polyethylene oxide gel in the surgical treatment of carpal tunnel syndrome (CTS) recurrences. Our case series included 39 patients (40 hands, one bilateral case) who underwent revision surgery for recurrent CTS (28 cases) or resistant CTS (12 cases). The mean age of the patients was 56 years. Read More

Am J Case Rep 2018 Nov 24;19:1398-1404. Epub 2018 Nov 24.

Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore, Singapore.

BACKGROUND Amyloid arthropathy and myopathy are complications of amyloidosis that can be associated with non-specific imaging findings, which may be challenging to interpret. The report is of a case of polyarticular amyloid arthropathy and myopathy in a 56-year-old man with multiple myeloma and includes a description of the radiographic, computed tomography (CT), and magnetic resonance imaging (MRI) findings. CASE REPORT A 56-year-old man with multiple myeloma presented with chronic polyarticular pain and swelling. Read More

Orthop Traumatol Surg Res 2018 Nov 20. Epub 2018 Nov 20.

Service orthopédie et traumatologie, boulevard Tanguy Prigent, 29609 Brest, France.

Objectives: Volkmann's ischemic contracture is rare and surgical treatment remains a challenge. The goal of treatment is to obtain permanent recovery of joint range of motion and strength. The goal of this study was to evaluate the functional and socioprofessional outcome of surgical treatment of Volkmann's ischemic contracture. Read More

Hand Clin 2019 Feb;35(1):85-92

Upper Limb Unit, Wrightington Hospital, Hall Lane, Appley Bridge, Wigan, Lancashire WN6 9EP, UK.

The minimally invasive nature of wrist and small joint arthroscopy renders it particularly suitable for the application of the wide-awake local anesthesia no tourniquet (WALANT) technique. The application of WALANT wrist and small joint arthroscopy has given surgeons the ability to visualize both static and dynamic movements of a joint, to show the pathology and discuss with the patient, and to visualize a patient's repaired structures. This reinforces confidence in surgeons and encourages patients to comply with postoperative rehabilitation. Read More

Hand Clin 2019 Feb;35(1):51-58

Departament of Surgery and Orthopedics, Botucatu Medical School, São Paulo State University, UNESP, Av. Professor Mario Rubens Montenegro s/n, Botucatu, São Paulo 18 618-687, Brazil.

The authors report the introduction and development of wide awake hand surgery under local anesthesia no tourniquet (WALANT) in South America, specifically in Brazil, where thousands of cases have already been performed with this technique. This was largely stimulated by Dr Lalonde's first visit to Brazil in 2012. The authors began with smaller procedures such as trigger fingers and carpal tunnels, which were easily implemented. Read More

J Neuroimaging 2018 Nov 23. Epub 2018 Nov 23.

Department of Orthopedic Surgery, St. Luke's Hospital, Thessaloniki, Greece.

Background And Purpose: We present the clinical, electrophysiological, and nerve ultrasound findings in cases of persistent carpal tunnel syndrome (PCTS).

Methods: Eighteen PCTS patients underwent evaluation with the Boston Carpal Tunnel Syndrome Questionnaire (BCTSQ), electrophysiology, and nerve ultrasound with a mean of 3.5 months (SD ± 1. Read More

Vet Surg 2018 Nov 23. Epub 2018 Nov 23.

Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois Urbana-Champaign, Urbana, Illinois.

Objective: To describe and report outcomes after lateral translation of the manus for limb-sparing management of distal radial osteosarcoma in dogs.

Study Design: Retrospective case series.

Study Population: Eighteen client-owned dogs. Read More

Front Neurol 2018 7;9:923. Epub 2018 Nov 7.

Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, United States.

In this study, we explored whether improved hand function is possible in poststroke chronic hemiparetic individuals with severe upper limb motor impairments when they participate in device-aided task-specific practice. Eight participants suffering from chronic stroke (>1-year poststroke, mean: 11.2 years) with severely impaired upper extremity movement (Upper Extremity Subscale of the Fugl-Meyer Motor Assessment (UEFMA) score between 10 and 24) participated in this study. Read More

Acta Ortop Bras 2018 ;26(5):286-289

Grupo de Mão e Microcirurgia, Instituto de Ortopedia e Traumatología, Hospital das Clinicas (HC-FMUSP), Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.

Objective: Treatment of Kienböck's disease is challenging and the variability of results, despite the surgical technique, shows that there must be other aspects that can influence outcomes. The objective of this study is determine, through arthroscopic approach, the pattern of impairment of the carpal bones in Lichtman stage III patients.

Method: Wrist arthroscopy was performed in patients with symptoms and evidence of lunate necrosis on x-rays, with signs of 3A and 3B stages. Read More

Arthritis Res Ther 2018 Nov 21;20(1):260. Epub 2018 Nov 21.

Department of Rheumatology C1-R, Leiden University Medical Centre, PO Box 9600, Leiden, 2300RC, the Netherlands.

Objective: Subclinical joint inflammation in patients with arthralgia is predictive for progression to rheumatoid arthritis (RA). However, the time course of progression for bone marrow edema (osteitis), synovitis, and/or tenosynovitis is unsettled. This longitudinal study assessed the course of magnetic resonance imaging (MRI)-detected subclinical joint inflammation during progression to RA. Read More