131,843 results match your criteria Carotid Ultrasound
Neuroimage 2018 Dec 12. Epub 2018 Dec 12.
Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China. Electronic address:
Reduction in cerebral blood flow (CBF), one of the major metrics for cerebral perfusion, is associated with many brain disorders. Therefore, early characterization of CBF prior to occurrence of symptoms is essential for prevention of cerebral ischemic disorders. We hypothesized that large artery atherosclerosis might be a potential indicator for decline in cerebral perfusion. Read More
Neuroradiology 2018 Dec 14. Epub 2018 Dec 14.
Henan Provincial People's Hospital, Zhengzhou University, 7 Weiwu Road, Zhengzhou, 450003, Henan Province, China.
Purpose: The effects and complications of hybrid procedure (combined carotid endarterectomy and carotid stenting) to revascularize chronic long-segment occlusion of internal carotid artery (ICA) are currently unknown and the purpose of this study.
Methods: Sixty-five patients with long-segment occlusion of ICA were prospectively enrolled and divided into two groups of revascularization with hybrid operation (n = 30) and medication group (n = 35), and clinical and angiographic data were analyzed.
Results: The duration from symptom onset to revascularization ranged 17-120 days (mean 40. Read More
Sci Rep 2018 Dec 14;8(1):17864. Epub 2018 Dec 14.
Pediatric Endocrinology group, (Girona Biomedical Research Institute) IDIBGI, Girona, Spain.
Although alkaline phosphatase (ALP) correlates with cardiovascular risk in adults, there are no studies in children. We evaluated the association between serum ALP levels, calcium-phosphorus product (Ca*P) and cardiovascular risk markers in healthy children. Children aged 7. Read More
J Neurointerv Surg 2018 Dec 14. Epub 2018 Dec 14.
Lyerly Neurosurgery, Baptist Neurological Institute, Baptist Health, Jacksonville, Florida, USA.
Background: Treatment of acute cerebrovascular pathology, such as acute ischemic stroke or intracranial aneurysms, presents a challenge if an extracranial or intracranial stent is required; immediate platelet inhibition is vital. To date, there is no standardized approach for antiplatelet inhibition in an acute setting.
Objective: To report our preliminary experience and lessons learnt using cangrelor in acute neurointervention. Read More
J Vasc Surg 2018 Dec 11. Epub 2018 Dec 11.
CAMC Health Education and Research Institute, Charleston, WVa.
Background: The incidence of carotid in-stent stenosis has been reported to vary between 1% and 30%. Most published studies have short follow-up, which may lead to underestimation of the incidence of in-stent stenosis. This study analyzed the incidence of ≥50% and ≥80% in-stent stenosis using validated duplex ultrasound criteria and its clinical implications. Read More
Comput Biol Med 2018 Nov 13;104:267-277. Epub 2018 Nov 13.
Department of Electronic Engineering, Information School, Yunnan University, Kunming, Yunnan, 650091, China.
An ultrasound simulation model incorporating incident and reflected wave propagations is proposed to provide a realistic data source for validation of transit time (TT)-based local pulse wave velocity (PWV) estimation algorithms. First, the incident wave (IW) and reflected wave (RW) at a certain position over a common carotid artery (CCA) are estimated. Then, the propagating pulse waves (PWs) along the CCA are modelled with the synthesizations of the estimated IWs and RWs, whose occurrences are delayed in opposite sequences according to a preset PWV. Read More
Clin Chim Acta 2018 Dec 11. Epub 2018 Dec 11.
Department of Clinical-Laboratory and Experimental-Research Medicine, Toho University Sakura Medical Center, 564-1 Shimoshizu, Sakura 285-8741, Japan. Electronic address:
Background: The levels of plasma sLR11, released from intimal SMCs, are positively associated with intima-media thickness (IMT) in asymptomatic subjects. We have evaluated the yet unknown pathological significance of sLR11 for plaque conditions in patients with carotid artery stenosis.
Methods: The presence of LR11 in carotid plaques was investigated using autopsy specimens. Read More
Life Sci 2018 Dec 11. Epub 2018 Dec 11.
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Helwan University, Ein Helwan, Cairo 11795, Egypt. Electronic address:
Aims: Cerebral ischemia reperfusion (I/R) is a neurovascular disease leading to cerebral damage. It was found that postmenopausal women are liable to more dangerous effects than men at same age in stroke. The objective of this study is to investigate the neuroprotective effect of zeranol against cerebral ischemia reperfusion in ovariectomized rats. Read More
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1893-1896
Department of Otolaryngology Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
To explore the application and to evaluate the advantage of image navigation assisted nasal endoscopic surgery in optic nerve decompression. Sixty patients accepted the image navigation assisted nasal endoscopic surgery therapy in optic nerve decompression were included in this retrospective study and followed up for about six months to four years. The visual acuity was improved in 16 cases with visual acuity above light. Read More
Laryngoscope 2018 Dec 13. Epub 2018 Dec 13.
Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital Zurich, Zurich, Switzerland.
Objectives/hypothesis: To investigate the association between epistaxis and atherosclerotic cardiovascular disease.
Study Design: Case-control cohort study.
Methods: This study included patients from the tertiary-care ear, nose, and throat department at the University Hospital of Zurich between December 1, 2016 and June 1, 2017. Read More
Proteomics Clin Appl 2018 Dec 13:e1800135. Epub 2018 Dec 13.
A. K. Lucas-Herald, B. Mansoorian, W. Mullen, C. Delles, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, G12 8TA, UK.
Background: Progeria-like syndromes offer a unique insight into ageing. Here we present the case of a boy affected with mandibuloacral dysplasia and compound heterozygous mutations in ZMPSTE24.
Methods: Capillary electrophoresis-mass spectroscopy was used for proteome analysis to analyse peptides previously found to be differentially regulated in chronic kidney disease (273 peptides defining the CKD273 classifier), coronary artery disease (238 peptides defining the CAD238 classifier) and ageing (116 peptides defining the AGE116 classifier). Read More
Emerg Med Australas 2018 Dec 10. Epub 2018 Dec 10.
Emergency Department, Mater Hospital Brisbane, Brisbane, Queensland, Australia.
Diab Vasc Dis Res 2018 Dec 14:1479164118816661. Epub 2018 Dec 14.
1 School of Medicine, Tzu Chi University, Hualien, Taiwan.
Background:: Sclerostin and Dickkopf-1 are extracellular inhibitors of the canonical Wnt/β-catenin signalling pathway, which is implicated in the development of arterial stiffness. However, the correlation between aortic stiffness and sclerostin or Dickkopf-1 levels in patients with type 2 diabetes mellitus is unknown.
Methods:: Fasting blood samples were collected from 125 patients with type 2 diabetes mellitus. Read More
Pediatr Cardiol 2018 Dec 13. Epub 2018 Dec 13.
Department of Pediatrics, Pediatric Cardiology, Yale School of Medicine, 333 Cedar St, LLCI 302, New Haven, CT, 06510, USA.
The objective of this study is to identify fetal echocardiographic measures that predict postnatal coarctation of the aorta (CoA). A retrospective review of patients from 2013 to 2017 identified 13 cases of prenatal diagnosis of CoA confirmed postnatally and 14 cases of prenatal diagnosis of CoA with normal arches postnatally. There were 30 controls. Read More
eNeurologicalSci 2018 Dec 22;13:46-48. Epub 2018 Nov 22.
Krankenanstalt Rudolfstiftung, Juchgasse 25, A-1030 Wien, Austria.
Takotsubo syndrome (TTS) is a transient transient left ventricular dysfunction, predominantly affecting elderly women and often preceded by emotional or physical stress. TTS may be the cause as well as the consequence of stroke. We report a 82-years old female with a history of long-standing untreated arterial hypertension who was hospitalized because of a left-sided tongue paralysis and dysarthria. Read More
Biomark Insights 2018 29;13:1177271918812467. Epub 2018 Nov 29.
School of Life Sciences and Centre for Health Technologies, University of Technology Sydney, Broadway, NSW, Australia.
Atherosclerosis is the underlying cause of most myocardial infarction (MI) and ischaemic stroke episodes. An early sign of atherosclerosis is hypertrophy of the arterial wall. It is known that increased intima media thickness (IMT) is a non-invasive marker of arterial wall alteration, which can easily be assessed in the carotid arteries by high-resolution B-mode ultrasound. Read More
J Stroke Cerebrovasc Dis 2018 Dec 11. Epub 2018 Dec 11.
Meshalkin National Medical Research Center, Ministry of Public Health of the Russian Federation, Novosibirsk, Russian Federation.
Background: The objectives of our research were to identify whether the new method of carotid endarterectomy (CEA) with autoarterial remodeling of bifurcation of the common carotid artery (ARBCCA) influences daily parameters of blood pressure and heart rate (HR) while monitoring them on a daily basis and to assess the efficacy of the suggested method.
Materials And Methods: It is a prospective randomized comparative study. The first group (n = 100) included patients that underwent ARBCCA, the second group (n = 100) included patients that underwent "classic" CEA with xenopericardial patch closure. Read More
Int J Cardiol 2018 Dec 5. Epub 2018 Dec 5.
Department of Biomedical and Molecular Sciences, Queen's University, 18 Stuart Street, Kingston, K7L 3N6, ON, Canada; Department of Medicine, Division of Cardiology, Cardiovascular Imaging Network at Queen's (CINQ), Queen's University, 76 Stuart Street, Kingston, K7L 2V7, ON, Canada. Electronic address:
Background: Coronary Artery Disease (CAD) is the leading cause of death worldwide. Ultrasound-detected carotid plaque has been previously shown to predict significant CAD. Despite this evidence, carotid plaque assessment has not been implemented in cardiac risk screening, likely due to the cost associated with a formal carotid ultrasound examination. Read More
Cell Transplant 2018 Dec 14:963689718817760. Epub 2018 Dec 14.
1 Department of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing, China.
There has been no gold standard for intraoperative monitoring in carotid endarterectomy (CEA) till now. The purpose of the current study was to investigate the value of near-infrared spectroscopy (NIRS) monitoring in CEA and explore the thresholds for intraoperative cerebral hypoperfusion. Eighty-four consecutive patients who underwent CEA surgery in Xuan Wu Hospital of Capital Medical University from August 2015 to June 2016 were enrolled in this study. Read More
J Neurosurg 2018 Nov 1:1-4. Epub 2018 Nov 1.
A carotid web is a shelf-like intraluminal filling defect typically arising from the posterolateral wall of the proximal internal carotid artery. It is recognized as a possible cause of ischemic stroke in young adults. However, its etiopathogenesis is controversial and remains to be fully elucidated. Read More
J Neurosurg 2018 Nov 1:1-12. Epub 2018 Nov 1.
OBJECTIVEThe foramen lacerum is a relevant skull base structure that has been neglected for many years. From the endoscopic endonasal perspective, the foramen lacerum is a key structure due to its location at the crossroad between the sagittal and coronal planes. The objective of this study was to provide a detailed investigation of the surgical anatomy of the foramen lacerum and its adjacent structures based on anatomical dissections and imaging studies, propose several relevant key surgical landmarks, and demonstrate the surgical technique for its full exposure with several illustrative cases. Read More
J Neurosurg 2018 Nov 1:1-10. Epub 2018 Nov 1.
OBJECTIVETumors involving Meckel's cave remain extremely challenging because of the surrounding complex neurovascular structures and deep-seated location. The authors investigated a new minimal-access technique using the endoscopic transorbital approach (eTOA) through the superior eyelid crease to Meckel's cave and middle cranial fossa lesions and reviewed the most useful surgical procedures and pitfalls of this approach.METHODSBetween September 2016 and January 2018, the authors performed eTOA in 9 patients with tumors involving Meckel's cave and the middle cranial fossa. Read More
J Neurosurg Pediatr 2018 Dec 1:1-8. Epub 2018 Dec 1.
OBJECTIVECarotid body tumors (CBTs), extraadrenal paragangliomas, are extremely rare neoplasms in children that often require multimodal surgical treatment, including preoperative anesthesia workup, embolization, and resection. With only a few cases reported in the pediatric literature, treatment paradigms and surgical morbidity are loosely defined, especially when carotid artery infiltration is noted. Here, the authors report two cases of pediatric CBT and provide the results of a systematic review of the literature. Read More
Acta Biochim Biophys Sin (Shanghai) 2018 Dec 13. Epub 2018 Dec 13.
Institute for Health and Sport, Victoria University, Melbourne VIC, Australia.
Rheumatology (Oxford) 2018 Dec 12. Epub 2018 Dec 12.
Department of Rheumatology, Translational Immunology and Medical Outpatient Clinic, University Hospital Basel, Basel, Switzerland.
Objectives: To assess changes of arterial vessel wall morphology in large vessel GCA patients (LV-GCA) by repeated US.
Methods: Patients with LV-GCA on US examination were followed up 6, 12 and 24 months after diagnosis by US of the temporal, vertebral, carotid (common, internal, external), subclavian, axillary, femoral (deep, superficial and common) and popliteal arteries. Clinical and laboratory data were assessed at each visit. Read More
Neurosurgery 2018 Dec 13. Epub 2018 Dec 13.
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
A A Pract 2018 Dec 7. Epub 2018 Dec 7.
Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin.
A patient presented with a stab injury caused by a knife penetrating the orbital floor and maxillary sinus along the skull base with the tip situated adjacent to the left internal carotid artery. A flexible fiberoptic bronchoscope loaded with an endotracheal tube was initially positioned superior to the vocal cords and advanced into the trachea immediately following induction. The blade was removed after occluding endovascular balloons were positioned distal and proximal to the potential internal carotid artery injury site. Read More
A A Pract 2018 Dec 11. Epub 2018 Dec 11.
From the Department of Anesthesiology, Northwestern Memorial Hospital, Chicago, Illinois.
An 86-year-old female with previously diagnosed congenitally absent right internal carotid artery presented for total shoulder arthroplasty. Bedside ultrasonography confirmed the anomaly and identified several arterial collateral vessels. No aberrant vessels were seen traversing the brachial plexus. Read More
Acta Medica (Hradec Kralove) 2018 ;61(3):86-92
Division of Rheumatology, Department of Internal Medicine, Malatya State Hospital, Malatya, Turkey.
Background: Vasculopathy is a major cause of mortality and morbidity in Behcet's Disease (BD). Subclinical atherosclerosis can even be detected in the early stage of BD. Soluble tumor necrosis factor-like (TNF) weak inducer of apoptosis (TWEAK) is known as a good marker of the inflammation in vascular tree. Read More
Neurosurg Rev 2018 Dec 12. Epub 2018 Dec 12.
Department of Neurosurgery, Goethe-University Hospital, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.
Patients with ruptured aneurysms of carotid bifurcation artery seem to suffer less often from cerebral vasospasm and early brain injury and have a better clinical outcome. Aim of our study was to identify differences in clinical course and outcome in aneurysms of terminus segments (carotid bifurcation artery and basilar tip) compared to aneurysms of other aneurysm locations except carotid bifurcation artery and basilar tip. Patients with SAH were entered into a prospectively collected database (1999 to June 2014). Read More
Acta Neurol Belg 2018 Dec 12. Epub 2018 Dec 12.
Uniwersytet Medyczny im Piastow Slaskich we Wroclawiu, Wrocław, Dolnośląskie, Poland.
Stenosis of arteries that supplies blood to the brain is one of the main causes of ischemic stroke which is the third most common cause of deaths in Europe. Atherosclerosis of carotid and vertebral arteries is responsible for 20% of the ischemic stroke cases. Stenosis may be either asymptomatic or manifested with typical neurological symptoms including motor and sensory disturbances as well as disturbances in vision and speech. Read More
Radiol Med 2018 Dec 12. Epub 2018 Dec 12.
Department of BIOMORF, University of Messina, Messina, Italy.
Carotid atherosclerosis is very important in the pathogenesis of cerebral ischemia. Ultrasonography (US) and magnetic resonance imaging (MRI) are the predominant noninvasive techniques capable to identify the presence and stage of intra-plaque hemorrage. In this work, we propose a novel dedicated phantom that can be used for both US and MRI scanners to evaluate carotid atherosclerotic lesions. Read More
J Mol Neurosci 2018 Dec 12. Epub 2018 Dec 12.
Institute of Biomedicine, Jinan University, Guangzhou, China.
Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) belong to the same peptide family and exert a variety of biological functions. Both PACAP and VIP have protective effects in several tissues. While PACAP is known to be a stronger retinoprotective peptide, VIP has very potent anti-inflammatory effects. Read More
Exp Ther Med 2018 Dec 12;16(6):5327-5333. Epub 2018 Oct 12.
Department of Cardiology, Dongguan Third People's Hospital, Dongguan, Guangdong 523326, P.R. China.
Leptin has been reported to be expressed in carotid atherosclerotic plaques, where it can promote lesion instability. Matrix metalloproteinases (MMPs) produced by smooth muscle cells (SMCs) are known to contribute to the weakening of atherosclerotic plaques via the degradation of extracellular matrix (ECM) proteins. The present study investigated whether leptin promotes plaque rupture by increasing the expression of MMP in SMCs and . Read More
Exp Ther Med 2018 Dec 16;16(6):5253-5257. Epub 2018 Oct 16.
Department of Neurosurgery, Jingmen First People's Hospital, Jingmen, Hubei 448000, P.R. China.
Correlations of carotid intima-media thickness (IMT), atherosclerotic plaque stability, serum inflammatory factors and serum matrix metalloproteinase (MMP)-2 and MMP-9 levels with the condition of disease in patients with acute cerebral infarction were analyzed to explore the predictive value of these risk factors. A total of 56 patients diagnosed with acute cerebral infarction in Jingmen First People's Hospital from February 2016 to January 2017 were selected and divided into the plaque stability group (n=25) and plaque instability group (n=31). Our results showed that the level of total cholesterol (TC) in the plaque instability group was significantly higher than that in the plaque stability group (P<0. Read More
J Cardiovasc Magn Reson 2018 Dec 13;20(1):80. Epub 2018 Dec 13.
Department of Endocrinology and Internal Medicine and Medical Research Laboratories, Aarhus University Hospital, Nørrebrogade 44, 8000, Aarhus C, Denmark.
Background: Women with Turner Syndrome have an increased risk for aortic dissection. Arterial stiffening is a risk factor for aortic dilatation and dissection. Here we investigate if arterial stiffening can be observed in Turner Syndrome patients and is an initial step in the development of aortic dilatation and subsequent dissection. Read More
Front Pediatr 2018 19;6:333. Epub 2018 Nov 19.
Department of Epidemiology, School of Public Health, Shandong University, Jinan, China.
Subclinical target organ damage (TOD) has been common in hypertensive children, but there is limited data in the Chinese pediatric population. This study aimed to investigate the prevalence of subclinical TOD in the Chinese hypertensive children and adolescents. A cross-sectional study was performed in children and adolescents from four schools in Jinan, China between September 2012 and September 2014. Read More
Clin Kidney J 2018 Dec 6;11(6):846-852. Epub 2018 Jun 6.
Department of Internal Medicine-UNESP, Univ Estadual Paulista, Botucatu, Brazil.
Background: In animal models, the mammalian target of rapamycin inhibitors (mTORIs) may prevent atherogenesis by the regulation of homeostasis of cholesterol and by a reduced inflammatory response. The aim of this study is to compare the carotid intima-media thickness (cIMT) between tacrolimus/mycophenolate and tacrolimus/sirolimus at low doses. The cIMT is considered a surrogate marker of atherosclerosis. Read More
Iran J Basic Med Sci 2018 Oct;21(10):998-1003
Addiction Research Center, Shahroud University of Medical Sciences, Shahroud, Iran.
Objectives: According to recent the findings, sulfur dioxide (SO) is produced by the cardiovascular system, influencing some major biological processes. Based on previous research, SO exhibits antioxidant effects and inhibits apoptosis following cardiac ischemia/reperfusion. Therefore, the objective of the current study was to examine the neuroprotective impact of SO2 following global cerebral ischemia/reperfusion (I/R). Read More
Scanning 2018 5;2018:6340425. Epub 2018 Nov 5.
Department of Mechanical, Materials and Aerospace Engineering, School of Engineering, University of Liverpool, L69 3GH, UK.
Using the atomic force microscopy- (AFM-) PeakForce quantitative nanomechanical mapping (QNM) technique, we have previously shown that the adventitia of the human internal mammary artery (IMA), tested under dehydrated conditions, is altered in patients with a high degree of arterial stiffening. In this study, we explored the nanoscale elastic modulus of the tunica media of the IMA in hydrated and dehydrated conditions from the patients with low and high arterial stiffening, as assessed by carotid-femoral pulse wave velocity (PWV). In both hydrated and dehydrated conditions, the medial layer was significantly stiffer in the high PWV group. Read More
Neuroophthalmology 2018 Dec 26;42(6):404-405. Epub 2018 Mar 26.
Department of Ophthalmology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Bilateral intracavernous internal carotid artery aneurysms are rare. They are more common in elderly females and are associated with hypertension. We present the computed tomography angiography findings of an 81-year-old female with history of hypertension who came complaining of diplopia and headache. Read More
Front Neurol 2018 20;9:940. Epub 2018 Nov 20.
Klinik für Neuroradiologie, Klinikum Stuttgart, Stuttgart, Germany.
Various endovascular approaches to treat acute ischemic stroke caused by extra- intracranial tandem occlusions (TO) exist: percutaneous transluminal angioplasty with or without emergent extracranial carotid stenting (ECS) due to high-grade stenosis preceded or followed by intracranial mechanical and/or aspiration thrombectomy (MT). Which treatment strategy to use is still a matter of debate. From our ongoing prospective stroke registry we retrospectively analyzed 1,071 patients with anterior circulation stroke getting endovascular treatment within 6 h of symptom onset. Read More
Front Physiol 2018 22;9:1664. Epub 2018 Nov 22.
Department of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany.
Intraventricular hemorrhage (IVH) is a frequent major damage to the brain of premature babies ≤32 weeks gestational age, and its incidence (20-25%) has not significantly changed lately. Because of the intrinsic fragility of germinal matrix blood vessels, IVH occurs following disruption of subependymal mono-layer arteries and is generally attributed to ischemia-reperfusion alterations or venous congestion, which may be caused by turn of the head. Therefore, supine position with the head in a midline position is considered a standard position for preterm infants during their first days of life. Read More
Phys Med Biol 2018 Nov 14. Epub 2018 Nov 14.
Laboratory of Biorheology and Medical Ultrasonics , University of Montreal Hospital Research Center, 900 St-Denis, Montreal, Quebec, CANADA.
Ultrasound noninvasive vascular elastography (NIVE) has shown its potential to measure strains of carotid arteries to predict plaque instability. When two-dimensional (2-D) strain estimation is performed, either in longitudinal or cross-sectional view, only in-plane motions are considered. The motions in elevation direction (i. Read More
Med Biol Eng Comput 2018 Dec 7. Epub 2018 Dec 7.
Biomedical Flow Dynamics Laboratory, Institute of Fluid Science, Tohoku University, Sendai, Miyagi, 980-8577, Japan.
Computational fluid dynamics (CFD) studies of intracranial hemodynamics often use Newtonian viscosity model to close the shear rate term in the Navier-Stokes equation. This is based on a commonly accepted hypothesis which state that non-Newtonian effects can be neglected in intracranial blood flow. This study aims to examine the validity of such hypothesis to guide future CFD studies of intracranial hemodynamics. Read More
Eur Radiol 2018 Dec 6. Epub 2018 Dec 6.
Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Objectives: To compare visualization of carotid plaques and vessel walls between 3D T1-fast spin echo imaging with conventional SPACE (T1-SPACE) and with a prototype compressed sensing T1-SPACE (CS-T1-SPACE) METHODS: This retrospective study was approved by the institutional review board. Participants comprised 43 patients (36 males, 7 females; mean age, 71 years) who underwent carotid MRI including T1-SPACE and CS-T1-SPACE. The quality of visualization for carotid plaques and vessel walls was evaluated using a 5-point scale, and signal intensity ratios (SRs) of the carotid plaques were measured and normalized to the adjacent sternomastoid muscle. Read More
Eur J Nutr 2018 Dec 6. Epub 2018 Dec 6.
Hypertension in Africa Research Team (HART), North-West University, Private Bag X1290, Potchefstroom, 2522, South Africa.
Purpose: Despite selenium's beneficial effects in counteracting oxidative stress, inflammation, and vascular endothelial dysfunction, controversial results exist regarding the long-term associations between selenium and atherosclerosis, arterial stiffness, and hypertension. We investigated in normal and selenium-deficient groups (and the total group), whether serum selenium relates to measures of large artery structure and function over 10 years.
Methods: This longitudinal study included black adults from rural and urban areas in South Africa. Read More
Drug Metab Dispos 2018 Dec 6. Epub 2018 Dec 6.
University of Georgia
Permethrin (PER), a Type I pyrethroid, is the most widely used insecticide in domestic settings in the U.S. The overall objective of this study was to assess the efficiency of the blood-brain barrier (BBB) as an obstacle to the cis (CIS) and trans (TRANS) isomers of PER, and to determine whether its barrier function changes during maturation of the rat. Read More
Lancet 2018 Dec 3. Epub 2018 Dec 3.
Unit of Epidemiology and Global Health, Umeå University, Umeå, Sweden.
Background: Primary prevention of cardiovascular disease often fails because of poor adherence among practitioners and individuals to prevention guidelines. We aimed to investigate whether ultrasound-based pictorial information about subclinical carotid atherosclerosis, targeting both primary care physicians and individuals, improves prevention.
Methods: Visualization of asymptomatic atherosclerotic disease for optimum cardiovascular prevention (VIPVIZA) is a pragmatic, open-label, randomised controlled trial that was integrated within the Västerbotten Intervention Programme, an ongoing population-based cardiovascular disease prevention programme in northern Sweden. Read More