44,489 results match your criteria Carotid Ultrasound


Radiation-induced vascular changes in the intracranial irradiation field in medulloblastoma survivors: An MRI study.

Radiother Oncol 2019 Apr 10;136:50-55. Epub 2019 Apr 10.

Department of Pediatric Hematology/Oncology/Hemostaseology, University Medical Center of the Johannes Gutenberg-University Mainz, Germany.

Background And Purpose: While survival times after treatment of medulloblastoma are increasing, little is known about radiochemotherapy (RCT)-induced cerebrovascular changes. High resolution vessel wall imaging (VWI) sequences are an emerging tool for the evaluation of cerebrovascular diseases. We performed VWI in medulloblastoma long-term survivors to screen for late sequelae of RCT. Read More

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http://dx.doi.org/10.1016/j.radonc.2019.03.017DOI Listing

Optimal cut-off criteria for duplex ultrasound compared with computed tomography angiography for the diagnosis of restenosis in stented carotid arteries in the international carotid stenting study.

Eur Stroke J 2017 Mar 4;2(1):37-45. Epub 2016 Nov 4.

Department of Neurology, Academic Medical Center, Amsterdam, the Netherlands.

Introduction: Previous studies that reported duplex-ultrasound cut-off criteria, based on blood velocity parameters, for the degree of stenosis in a stented carotid artery were either retrospective, or the reference test was carried out only when a patient was suspected of having restenosis at duplex ultrasound, which is likely to have resulted in verification bias. We performed a prospective study of diagnostic accuracy to find new blood velocity cut-offs in duplex ultrasound for in-stent restenosis.

Patients And Methods: Stented patients within the international carotid stenting study were eligible. Read More

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http://dx.doi.org/10.1177/2396987316678361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453175PMC

Association of nuts and unhealthy snacks with subclinical atherosclerosis among children and adolescents with overweight and obesity.

Nutr Metab (Lond) 2019 8;16:23. Epub 2019 Apr 8.

1Department of Nutrition, School of Health, Qazvin University of Medical Sciences, Qazvin, Iran.

Background: The process of atherosclerosis begins early in childhood and usually remains asymptomatic until later in life. Carotid intima-media thickness (cIMT) as a marker of subclinical atherosclerosis could identify early vascular alterations. Unhealthy snacks consumption is associated with obesity and other CVD risk factors in children and adolescents. Read More

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http://dx.doi.org/10.1186/s12986-019-0350-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454780PMC

Correlations of carotid intima-media thickness with endothelial function and atherosclerosis degree in patients with type 2 diabetes mellitus.

Clin Hemorheol Microcirc 2019 Apr 19. Epub 2019 Apr 19.

Department of Ultrasound, Weihai Central Hospital, Weihai, Shandong, China.

Objective: To investigate the correlation of carotid intima-media thickness (IMT) with endothelial function and atherosclerosis degree in patients with type 2 diabetes mellitus.

Methods: A total of 80 patients with type 2 diabetes mellitus admitted and treated in our hospital from January 2017 to January 2018 were selected and randomly divided into two groups (n = 40). Patients who were definitely diagnosed with type 2 diabetes mellitus were selected as observation group, and individuals who received health examination and were excluded from type 2 diabetes mellitus were enrolled as control group. Read More

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http://dx.doi.org/10.3233/CH-180486DOI Listing

3-D Strain Imaging of the Carotid Bifurcation: Methods and in-Human Feasibility.

Ultrasound Med Biol 2019 Apr 17. Epub 2019 Apr 17.

Medical Ultrasound Imaging Center, Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

Atherosclerotic plaque development in the carotid artery bifurcation elevates the risk for stroke, which is often initiated by plaque rupture. The risk-to-rupture of a plaque is related to its composition. Two-dimensional non-invasive carotid elastography studies have found a correlation between wall strain and plaque composition. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03015629193009
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http://dx.doi.org/10.1016/j.ultrasmedbio.2019.02.023DOI Listing
April 2019
2 Reads

Ranking of stroke and cardiovascular risk factors for an optimal risk calculator design: Logistic regression approach.

Comput Biol Med 2019 Mar 25;108:182-195. Epub 2019 Mar 25.

Stroke Monitoring and Diagnostic Division, AtheroPoint™, Roseville, CA, USA. Electronic address:

Purpose: Conventional cardiovascular risk factors (CCVRFs) and carotid ultrasound image-based phenotypes (CUSIP) are independently associated with long-term risk of cardiovascular (CV) disease. In this study, 26 cardiovascular risk (CVR) factors which consisted of a combination of CCVRFs and CUSIP together were ranked. Further, an optimal risk calculator using AtheroEdge composite risk score (AECRS1. Read More

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http://dx.doi.org/10.1016/j.compbiomed.2019.03.020DOI Listing
March 2019
1.240 Impact Factor

Ultrasonic Vascular Vector Flow Mapping for 2-D Flow Estimation.

Ultrasound Med Biol 2019 Apr 16. Epub 2019 Apr 16.

Healthcare Business Unit, Hitachi, Ltd., Tokyo, Japan.

A vascular vector flow mapping (VFM) method visualizes 2-D cardiac flow dynamics by estimating the radial component of flow from the Doppler velocities and wall motion velocities using the mass conservation equation. Although VFM provides 2-D flow, the algorithm is applicable only to bounded regions. Here, a modified VFM algorithm, vascular VFM, is proposed so that the velocities are estimated regardless of the flow geometry. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03015629193008
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http://dx.doi.org/10.1016/j.ultrasmedbio.2019.02.014DOI Listing
April 2019
1 Read

Plasm YKL-40 Levels Are Associated with Hypertension in Patients with Obstructive Sleep Apnea.

Biomed Res Int 2019 13;2019:5193597. Epub 2019 Mar 13.

Department of Otolaryngology, Beijing AnZhen Hospital, Capital Medical University, Beijing 100029, China.

Background: Obstructive sleep apnea (OSA) is a common disease. It can cause many serious complications. OSA may increase the risk of hypertension. Read More

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http://dx.doi.org/10.1155/2019/5193597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436335PMC
March 2019
1 Read

Efficacy and safety of 20% albumin fluid loading in healthy subjects: a comparison of four resuscitation fluids.

J Appl Physiol (1985) 2019 Apr 18. Epub 2019 Apr 18.

Flinders University, Australia.

Recently, buffered salt solutions and 20% albumin (small volume resuscitation) have been advocated as an alternative fluid for intravenous resuscitation. The relative comparative efficacy and potential adverse effects of these solutions have not been evaluated. In a randomized, double blind, cross over study of 6 healthy male subjects we compared the pulmonary and hemodynamic effects of intravenous administration of 30 ml/kg of 0. Read More

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http://dx.doi.org/10.1152/japplphysiol.01058.2018DOI Listing

Assessment of cardiac and vessel functions in childhood psoriasis

Turk J Med Sci 2019 Apr 18;49(2):617-623. Epub 2019 Apr 18.

Background/aim: Psoriasis is a chronic inflammatory disease. The effect of psoriasis on the cardiovascular system has not been studied in children before. We studied ventricular strain and vascular functions to assess early cardiovascular effects of psoriasis during childhood. Read More

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http://online.journals.tubitak.gov.tr/openDoiPdf.htm?mKodu=s
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http://dx.doi.org/10.3906/sag-1812-139DOI Listing
April 2019
2 Reads

Utility of transoral pharyngeal ultrasonography for puncture drainage of peritonsillar abscess.

Clin Case Rep 2019 Apr 19;7(4):839-840. Epub 2019 Feb 19.

Department of Neurology St. Marianna University School of Medicine Kawasaki Japan.

Puncture drainage is usually needed to treat peritonsillar abscess. However, inadvertent carotid artery puncture may result in devastating complications. Preoperative transoral carotid ultrasonography (TOCU) is useful to delineate the anatomical relationship between the abscess and carotid artery. Read More

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http://dx.doi.org/10.1002/ccr3.2032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452502PMC
April 2019
2 Reads

A Transoral Excision of a Deep Parotid Lobe Lesion Using Ultrasound-Guided Wire Localization: A Multi-disciplinary Team Approach.

J Maxillofac Oral Surg 2019 Jun 26;18(2):245-248. Epub 2018 Jul 26.

Present Address: Department of Head and Neck Surgery, University College London Hospital, 250 Euston Rd, Bloomsbury, London, NW1 2BU UK.

Purpose: Removing deep parotid lobe lesions often requires a mandibulotomy procedure which carries with it a risk of significant morbidity. A transoral approach may help mitigate against complications but is technically demanding due to limited access in an area with a close relation to the internal carotid artery.

Methods: We describe a multi-disciplinary approach with the use of intraoral ultrasound-guided wire localization of a low-grade acinic cell carcinoma located in the deep lobe of the right parotid gland. Read More

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http://dx.doi.org/10.1007/s12663-018-1137-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441451PMC

Angiopoietin-2 as a Marker of Retinopathy in Children and Adolescents With Sickle Cell Disease: Relation to Subclinical Atherosclerosis.

J Pediatr Hematol Oncol 2019 Apr 15. Epub 2019 Apr 15.

Departments of Pediatric.

Objectives: Angiopoietin-2 (Ang-2) is a multifaceted cytokine that functions in both angiogenesis and inflammation. A proangiogenic state has been found in adults with sickle cell disease (SCD), mainly because of elevated Ang-2 levels. We determined Ang-2 level in 40 children and adolescents with SCD compared with 40 healthy controls and assessed its relation to retinopathy as well as carotid intimamedia thickness (CIMT). Read More

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http://dx.doi.org/10.1097/MPH.0000000000001486DOI Listing
April 2019
2 Reads

Effect of carotid image-based phenotypes on cardiovascular risk calculator: AECRS1.0.

Med Biol Eng Comput 2019 Apr 15. Epub 2019 Apr 15.

Stroke Monitoring and Diagnostic Division, AtheroPoint™, 208 Otter Glen CT, Roseville, CA, 95661, USA.

Today, the 10-year cardiovascular risk largely relies on conventional cardiovascular risk factors (CCVRFs) and suffers from the effect of atherosclerotic wall changes. In this study, we present a novel risk calculator AtheroEdge Composite Risk Score (AECRS1.0), designed by fusing CCVRF with ultrasound image-based phenotypes. Read More

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http://dx.doi.org/10.1007/s11517-019-01975-2DOI Listing
April 2019
3 Reads

Long-Term Outcome of Symptomatic Patients Undergoing Hybrid Revascularisation for Extracranial Carotid Artery Tandem Stenosis.

Eur J Vasc Endovasc Surg 2019 Apr 12. Epub 2019 Apr 12.

Department of Vascular Surgery, University Medical Centre Utrecht, Utrecht University, the Netherlands. Electronic address:

Objectives: Carotid tandem lesions are a multilevel significant (>50%) atherosclerotic disease involving both the internal carotid artery (ICA) and either the ipsilateral common carotid artery (CCA) or the innominate artery (IA). These lesions may be challenging to treat. Current guidelines offer no definitive recommendation on the optimal treatment algorithm. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10785884183086
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http://dx.doi.org/10.1016/j.ejvs.2018.11.016DOI Listing
April 2019
2 Reads

Study of MRI brain findings and carotid US features in systemic sclerosis patients, relationship with disease parameters.

Arthritis Res Ther 2019 Apr 15;21(1):95. Epub 2019 Apr 15.

Division of Rheumatology, University of California in Los Angeles (Emeritus), Los Angeles, USA.

Background/objectives: Systemic sclerosis (SSc) is an autoimmune disease associated with immune abnormalities and widespread vascular lesions, including increased intimal and medial thickness. These changes may be reflected in early atherosclerosis and cardiovascular risks. We aimed in this study to examine the carotid artery intima-media thickness and MRI brain findings in SSc patients and compared them to a group of normal controls. Read More

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http://dx.doi.org/10.1186/s13075-019-1877-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466742PMC
April 2019
1 Read

Prevalence of extracranial carotid atherosclerosis in the patients with coronary artery disease in a tertiary hospital in Malaysia.

Medicine (Baltimore) 2019 Apr;98(15):e15082

Division of Neurology, Department of Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia.

There is limited information regarding the prevalence of extracranial carotid atherosclerosis in the patients with coronary artery disease (CAD) undergoing coronary artery bypass graft (CABG) surgery in South East Asia. The primary objective was to assess the prevalence of extracranial carotid stenosis, raised carotid intima media thickness (CIMT), and plaques in the patients with CAD undergoing elective CABG. The secondary objective was to evaluate the risk factors for extracranial carotid atherosclerosis. Read More

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http://dx.doi.org/10.1097/MD.0000000000015082DOI Listing
April 2019
2 Reads

Evaluation of subclinical atherosclerosis by ultrasound radiofrequency data technology in patients with Behçet's disease.

Int J Rheum Dis 2019 Apr 15. Epub 2019 Apr 15.

Department of Radiology, Diskapi Yildirim Beyazit Training and Research Hospital, University of Health Sciences, Ankara, Turkey.

Aim: We aimed to evaluate subclinical atherosclerosis based on carotid intima-media thickness (CIMT) and arterial stiffness measurements in patients with Behçet's disease (BD), using ultrasound (US) radiofrequency (RF) data technology.

Methods: We included 33 BD patients and 33 healthy controls in this study. The participants did not have any primary cardiovascular risk factors, such as diabetes mellitus, hypertension, hyperlipidemia and obesity. Read More

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http://dx.doi.org/10.1111/1756-185X.13579DOI Listing
April 2019
1 Read

Clinical feasibility study of 3D intracranial magnetic resonance angiography using compressed sensing.

J Magn Reson Imaging 2019 Apr 13. Epub 2019 Apr 13.

Department of Radiology, Peking University First Hospital, Beijing, China.

Background: Compressed sensing (CS) has been widely used to improve the speed of MRI, but the feasibility of application in 3D intracranial MR angiography (MRA) needs to be evaluated in clinical practice.

Purpose: To evaluate the clinical feasibility of CS-MRA in comparison with conventional 3D-MRA (Con-MRA).

Study Type: Retrospective. Read More

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http://dx.doi.org/10.1002/jmri.26752DOI Listing
April 2019
1 Read
3.210 Impact Factor

CETP activity is not associated with carotid intima-media thickness in patients with poorly controlled type 2 diabetes.

Acta Diabetol 2019 Apr 12. Epub 2019 Apr 12.

Department of Endocrinology, Diabetes and Metabolic Disorders, Dijon University Hospital, Dijon, France.

Aim: The impact of cholesteryl ester transfer protein (CETP) on atherosclerotic development in humans remains unclear. Plasma cholesteryl ester transfer was shown to be associated with carotid intima-media thickness in type 2 diabetic (T2D) patients with adequate metabolic control. Since glycation of CETP may influence cholesteryl ester transfer processes, it is important to determine if plasma cholesteryl ester transfer is still a determinant of carotid intima-media thickness (IMT) in patients with poorly controlled diabetes. Read More

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http://dx.doi.org/10.1007/s00592-019-01340-7DOI Listing

Comparison of the effect of the right lateral tilt position and Trendelenburg position on the right internal jugular vein in healthy volunteers: A prospective observational study.

J Vasc Access 2019 Apr 12:1129729819838169. Epub 2019 Apr 12.

1 Department of Anesthesiology and Reanimation, Konya Education and Research Hospital, University of Health Sciences, Ministry of Health, Konya, Turkey.

Background: Central venous cannulation is an invasive procedure commonly used by many physicians. The aim of this study was to evaluate the effects of the right lateral tilt position on the cross-sectional area and size of the right internal jugular vein, and the relationship between the right internal jugular vein and the carotid artery.

Method: Forty healthy volunteers aged over 18 years were included in this prospective, observational study. Read More

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http://dx.doi.org/10.1177/1129729819838169DOI Listing

Utility of Complementary Magnetic Resonance Plaque Imaging and Contrast-Enhanced Ultrasound to Detect Carotid Vulnerable Plaques.

J Am Heart Assoc 2019 Apr;8(8):e011302

1 Department of Neurology National Cerebral and Cardiovascular Center Osaka Japan.

Background We aimed to improve the assessment quality of plaque vulnerability with combined use of magnetic resonance imaging and contrast-enhanced ultrasound ( CEUS ). Methods and Results We prospectively enrolled 71 patients with internal carotid artery stenosis who underwent carotid endarterectomy and performed preoperative CEUS and magnetic resonance plaque imaging. We distinguished high-signal-intensity plaques ( HIP s) and non- HIP s based on magnetization-prepared rapid acquisition with gradient echo images. Read More

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http://dx.doi.org/10.1161/JAHA.118.011302DOI Listing
April 2019
1 Read

Association between resting heart rate, VOmax and carotid intima-media thickness in middle-aged men.

Int J Cardiol Heart Vasc 2019 Jun 29;23:100347. Epub 2019 Mar 29.

Department of Sports Medicine, National Fitness Center, Republic of Korea.

Introduction: Low resting heart rate (RHR) and high cardiorespiratory fitness (VOmax) are associated with a reduction in cardiovascular events (CV). Carotid intima-media thickness (CIMT) has been suggested as a predictor of CV. The purpose of this study was to investigate the association between RHR, VOmax and CIMT. Read More

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http://dx.doi.org/10.1016/j.ijcha.2019.100347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441756PMC

Evaluation of the atherosclerotic burden in hypertensive patients with prediabetes.

Clin Investig Arterioscler 2019 Apr 7. Epub 2019 Apr 7.

Centro de Investigaciones Médico-Sanitarias, Universidad de Málaga, Málaga, España.

Aim: To assess the atherosclerotic burden in hypertensive patients with prediabetes without cardiovascular disease.

Patients And Methods: We included patients with hypertension and prediabetes (fasting blood glucose: 100-125mg/dL and/or glycohemoglobin A1c: 5.7-6. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02149168193001
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http://dx.doi.org/10.1016/j.arteri.2019.01.003DOI Listing
April 2019
1 Read

Effect of uric acid serum levels on carotid arterial stiffness and intima-media thickness: A high resolution Echo-Tracking Study.

Monaldi Arch Chest Dis 2019 Mar 27;89(1). Epub 2019 Mar 27.

Highly Specialized Rehabilitation Hospital in Motta Di Livenza, Cardiac Prevention and Rehabilitation Unit.

Serum uric acid (UA) has been shown to be a predictor of cardiovascular (CV) morbidity and mortality, and it may play a role in the pathogenesis of CV disease affecting vascular structure and function. However, there is limited evidence of its specific association with carotid artery stiffness and structure. The aim of our study was to evaluate whether UA is associated with early signs of atherosclerosis, namely local carotid arterial stiffness and intima-media thickening. Read More

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http://dx.doi.org/10.4081/monaldi.2019.1007DOI Listing
March 2019
1 Read

Peripatetic carotid artery simulating a carotid dissection on catheter angiography and CT angiography: a case report.

Clin Imaging 2019 Mar 30;56:73-76. Epub 2019 Mar 30.

Department of Diagnostic Radiology, Michigan Medicine, 1500 E Medical Center Dr, Ann Arbor, MI 48109, USA.

Retropharyngeal carotid arteries are a common clinically relevant anatomic variant. "Peripatetic" carotid arteries refer to change in position to and from a retropharyngeal location, and are a newly described finding. Knowledge of this phenomenon is important to avoid potential procedural complications as well as misdiagnosis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08997071193006
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http://dx.doi.org/10.1016/j.clinimag.2019.03.017DOI Listing
March 2019
2 Reads

Optimization of topological complexity for one-dimensional arterial blood flow models.

J R Soc Interface 2018 Dec;15(149):20180546

1 Norwegian University of Science and Technology , Trondheim , Norway.

As computational models of the cardiovascular system are applied in modern personalized medicine, maximizing certainty of model input becomes crucial. A model with a high number of arterial segments results in a more realistic description of the system, but also requires a high number of parameters with associated uncertainties. In this paper, we present a method to optimize/reduce the number of arterial segments included in one-dimensional blood flow models, while preserving key features of flow and pressure waveforms. Read More

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http://dx.doi.org/10.1098/rsif.2018.0546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303799PMC
December 2018

Carotid artery wave intensity in mid- to late-life predicts cognitive decline: the Whitehall II study.

Eur Heart J 2019 Apr 8. Epub 2019 Apr 8.

National Centre for Cardiovascular Preventions and Outcomes, UCL Institute of Cardiovascular Science, 1 St. Martin's Le Grand, London, UK.

Aims: Excessive arterial pulsatility may contribute to cognitive decline and risk of dementia via damage to the fragile cerebral microcirculation. We hypothesized that the intensity of downstream-travelling pulsatile waves measured by wave intensity analysis in the common carotid artery during mid- to late-life would be associated with subsequent cognitive decline.

Methods And Results: Duplex Doppler ultrasound was used to calculate peak forward-travelling compression wave intensity (FCWI) within the common carotid artery in 3191 individuals [mean ± standard deviation (SD), age = 61 ± 6 years; 75% male] assessed as part of the Whitehall II study in 2003-05. Read More

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http://dx.doi.org/10.1093/eurheartj/ehz189DOI Listing
April 2019
11 Reads

Prevalence of heterozygous familial hypercholesterolemia and combined hyperlipidemia phenotype in very young survivors of myocardial infarction and their association with the severity of atheromatous burden.

J Clin Lipidol 2019 Mar 11. Epub 2019 Mar 11.

Department of Cardiology, 401 General Military Hospital of Athens, Athens, Greece.

Background: Heterozygous familial hypercholesterolemia (HeFH) and combined hyperlipidemia (CHL) phenotype are associated with premature myocardial infarction (MI).

Objective: To assess the prevalence of HeFH and CHL phenotype among young survivors of MI and compare patients' characteristics with these 2 lipid disorders.

Methods: We recruited 382 young survivors of MI (≤40 years). Read More

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http://dx.doi.org/10.1016/j.jacl.2019.02.007DOI Listing
March 2019
2 Reads

Correlation between of small dense low-density lipoprotein cholesterol with acute cerebral infarction and carotid atherosclerotic plaque stability.

J Clin Lab Anal 2019 Apr 6:e22891. Epub 2019 Apr 6.

Department of Clinical Laboratory, Affiliated Hospital of North China University of Science and Technology, Tangshan, China.

Background: Acute cerebral infarction (ACI) is seriously harmful to human health worldwide. However, at present, the risk of disease onset is still not accurately predicted for some people.

Methods: Five hundred and nineteen patients with ACI and 300 healthy controls were included in this study. Read More

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http://dx.doi.org/10.1002/jcla.22891DOI Listing
April 2019
1 Read

Carotid artery imaging: The study of intra-plaque vascularization and hemorrhage in the era of the "vulnerable" plaque.

J Neuroradiol 2019 Apr 4. Epub 2019 Apr 4.

Department of Medical Imaging, AOU of Cagliari, University of Cagliari, Cagliari, Italy.

Intraplaque hemorrhage (IPH) is one of the main factors involved in atherosclerotic plaque (AP) instability. Its recognition is crucial for the correct staging and management of patients with carotid artery plaques to limit ischemic stroke. Imaging plays a crucial role in identifying IPH, even if the great variability of intraplaque vascularization and the limitations of our current imaging technologies make it difficult. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01509861183031
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http://dx.doi.org/10.1016/j.neurad.2019.03.009DOI Listing
April 2019
7 Reads

Clinical Applications of Superb Microvascular Imaging in the Liver, Breast, Thyroid, Skeletal Muscle, and Carotid Plaques.

J Ultrasound Med 2019 Apr 5. Epub 2019 Apr 5.

Department of Ultrasound, Shaoxing People's Hospital, Shaoxing Hospital, Zhejiang University School of Medicine, Shaoxing, China.

This article reviews the clinical applications of Superb Microvascular Imaging (SMI; Canon Medical Systems, Otawara, Japan) in the liver, breast, thyroid, skeletal muscle, and carotid plaques. Diseases that are closely associated with angiogenesis can be diagnosed by SMI in a relatively early phase, and using SMI can prevent adverse reactions associated with the contrast agents used in contrast-enhanced ultrasound. Super Microvascular Imaging also shows particular value in grading disease activities and monitoring therapeutic responses. Read More

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http://dx.doi.org/10.1002/jum.15008DOI Listing
April 2019
1 Read

Antiviral treatment does not improve subclinical atheromatosis in patients with chronic hepatitis caused by hepatitis C virus.

Gastroenterol Hepatol 2019 Apr 2. Epub 2019 Apr 2.

Servicio de Aparato Digestivo, Hospital Universitario Arnau de Vilanova, Lleida, España; Instituto de investigación Biomédica, Lleida, España; Universidad de Lleida (UdL), Lleida, España.

Introduction: Chronic infection with hepatitis C virus is a risk factor for developing atheromatous plaques, although the possible effect of virus clearance is unknown. Our aim was to determine whether or not subclinical atheromatosis improved and there was any modification in the composition of the plaques 12 months after eradication of hepatitis C virus by direct-acting antiviral agents.

Materials And Methods: Prospective study that included 85 patients with chronic hepatitis C virus infection in different stages of fibrosis who were on direct-acting antiviral agents. Read More

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http://dx.doi.org/10.1016/j.gastrohep.2019.02.002DOI Listing
April 2019
2 Reads

Carotid artery fibromuscular dysplasia: Ultrasound and CT imaging.

Echocardiography 2019 Apr 5. Epub 2019 Apr 5.

Division of Vascular Surgery, Department of Surgery, LSU Health Sciences Center, School of Medicine, New Orleans, Louisiana.

An asymptomatic 54-year-old Caucasian female was found to have a right carotid bruit located high in the cervical region. Carotid duplex ultrasound revealed carotid intimal disease with increased Doppler flow in the mid-distal right internal carotid artery (RICA) with color Doppler turbulence in the distal RICA. Computed tomography angiography (CTA) revealed a typical "string-of-beads" sign in both distal internal carotid artery (ICAs), diagnostic of fibromuscular dysplasia (FMD). Read More

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http://dx.doi.org/10.1111/echo.14322DOI Listing
April 2019
1 Read

Measurement of Internal Jugular Vein and Common Carotid Artery Diameter Ratio by Ultrasound to Estimate Central Venous Pressure.

Cureus 2018 Mar 5;10(3):e2277. Epub 2018 Mar 5.

Department of Internal Medicine, Shifa International Hospital, Islamabad, PAK.

Objective The objective of this study is to find a correlation between internal jugular vein (IJV) and common carotid artery (CCA) diameter ratio and central venous pressure (CVP) measurement and find a cut-off value for the IJV/CCA ratio to predict low CVP i.e. < 10 cm H0, for estimating the volume status in critically ill patients. Read More

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http://dx.doi.org/10.7759/cureus.2277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440552PMC

Extracranial Artery Stenosis Is Associated With Total MRI Burden of Cerebral Small Vessel Disease in Ischemic Stroke Patients of Suspected Small or Large Artery Origins.

Front Neurol 2019 21;10:243. Epub 2019 Mar 21.

Department of Neurology and Stroke Center, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.

Extracranial artery stenosis (ECAS) is related to individual imaging markers of cerebral small vessel disease (cSVD). However, little has been reported on the association between ECAS and the total burden of cSVD as assessed by magnetic resonance imaging (MRI). The purpose of this study was to investigate the relationship between ECAS and cSVD burden in patients with ischemic stroke of suspected small or large artery origin. Read More

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http://dx.doi.org/10.3389/fneur.2019.00243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437037PMC
March 2019
1 Read

Case report: The efficiency and safety of lomitapide in a homozygous familial hypercholesterolemic child.

J Clin Lipidol 2019 Mar 11. Epub 2019 Mar 11.

Lipid Clinic Heart Institute (InCor), University of Sao Paulo Medical School Hospital, Sao Paulo, Brazil; Hospital Israelita Albert Einstein, Sao Paulo, Brazil. Electronic address:

We report for the first time the efficiency and safety of a 49-month compassionate use of the microsomal transfer protein inhibitor lomitapide in a child with homozygous familial hypercholesterolemia. On average, 20 mg of lomitapide caused a 37% reduction in low-density lipoprotein cholesterol levels on top of ezetimibe and atorvastatin. The drug was well tolerated with no changes in liver enzymes and occurrence of steatosis on hepatic ultrasound. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19332874193004
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http://dx.doi.org/10.1016/j.jacl.2019.03.001DOI Listing
March 2019
5 Reads

Segment-specific association of carotid-intima-media thickness with cardiovascular risk factors - findings from the STAAB cohort study.

BMC Cardiovasc Disord 2019 Apr 4;19(1):84. Epub 2019 Apr 4.

Comprehensive Heart Failure Center Würzburg, University and University Hospital Würzburg, Straubmühlweg 15, 97080, Würzburg, Germany.

Background: The guideline recommendation to not measure carotid intima-media thickness (CIMT) for cardiovascular risk prediction is based on the assessment of just one single carotid segment. We evaluated whether there is a segment-specific association between different measurement locations of CIMT and cardiovascular risk factors.

Methods: Subjects from the population-based STAAB cohort study comprising subjects aged 30 to 79 years of the general population from Würzburg, Germany, were investigated. Read More

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http://dx.doi.org/10.1186/s12872-019-1044-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449987PMC

Inflammatory biomarkers and subclinical carotid atherosclerosis in HIV-infected and HIV-uninfected men in the Multicenter AIDS Cohort Study.

PLoS One 2019 4;14(4):e0214735. Epub 2019 Apr 4.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

Background: HIV-infected persons have an increased risk of atherosclerosis relative to uninfected individuals. Inflammatory processes may contribute to this risk. We evaluated the associations of 10 biomarkers of systemic inflammation (CRP, IL-6, sTNF-αR1 and 2), monocyte activation (CCL2, sCD163, sCD14), coagulation (fibrinogen, D-dimer), and endothelial dysfunction (ICAM-1) with subclinical carotid atherosclerosis among participants in the Multicenter AIDS Cohort Study (MACS). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214735PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448851PMC
April 2019
1 Read

Plasma acylcarnitines and progression of carotid artery atherosclerosis in HIV infection.

AIDS 2019 May;33(6):1043-1052

Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York.

Objective: To evaluate plasma acylcarnitine profiles and their relationships with progression of carotid artery atherosclerosis among individuals with and without HIV infection.

Design: Prospective cohort studies of 499 HIV-positive and 206 HIV-negative individuals from the Women's Interagency HIV Study and the Multicenter AIDS Cohort Study.

Methods: Twenty-four acylcarnitine species were measured in plasma samples of participants at baseline. Read More

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http://dx.doi.org/10.1097/QAD.0000000000002142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457128PMC
May 2019
3 Reads

All-Optical Rotational Ultrasound Imaging.

Sci Rep 2019 Apr 3;9(1):5576. Epub 2019 Apr 3.

Department of Medical Physics and Biomedical Engineering, University College London, Malet Place Engineering Building, London, WC1E 6BT, UK.

Miniaturised high-resolution imaging devices are valuable for guiding minimally invasive procedures such as vascular stent placements. Here, we present all-optical rotational B-mode pulse-echo ultrasound imaging. With this device, ultrasound transmission and reception are performed with light. Read More

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http://www.nature.com/articles/s41598-019-41970-z
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http://dx.doi.org/10.1038/s41598-019-41970-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447544PMC
April 2019
3 Reads

Serum Triglycerides Are Related to Chronic Kidney Disease (CKD) Stage 2 in Young and Middle-Aged Chinese Individuals During Routine Health Examination.

Med Sci Monit 2019 Apr 4;25:2445-2451. Epub 2019 Apr 4.

Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China (mainland).

BACKGROUND The aim of this study was to determine the risk factors for early chronic kidney disease (CKD) (GFR 60-89 ml/min/1.73 m²; CKD stage 2) in asymptomatic Chinese individuals undergoing routine health examination. MATERIAL AND METHODS This cross-sectional study enrolled 9100 individuals who received voluntary medical examinations between 10/01/2011 and 09/30/2017. Read More

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http://dx.doi.org/10.12659/MSM.913506DOI Listing

Methotrexate use, not interleukin 33, is associated with lower carotid intima-media thickness in patients with rheumatoid arthritis.

Adv Rheumatol 2019 Apr 3;59(1):15. Epub 2019 Apr 3.

School of Medicine, Federal University of Minas Gerais (Universidade Federal de Minas Gerais - UFMG), Avenida Alfredo Balena, 190, Bairro Santa Efigênia, Belo Horizonte, Minas Gerais, CEP 30130-100, Brazil.

Background: Rheumatoid arthritis is a risk factor for early mortality due to cardiovascular disease. Interleukin-33 appears to protect against the development of atherosclerosis. The purpose of this study was to investigate the relationship between serum levels of interleukin-33 and its soluble receptor with the presence of subclinical carotid atherosclerosis in rheumatoid arthritis patients. Read More

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http://dx.doi.org/10.1186/s42358-019-0060-1DOI Listing
April 2019
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Circulating Microparticles in Patients with Symptomatic Carotid Disease Are Related to Embolic Plaque Activity and Recent Cerebral Ischaemia.

Cerebrovasc Dis Extra 2019 Apr 3;9(1):9-18. Epub 2019 Apr 3.

Radiological Sciences in the Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, United Kingdom.

Background And Purpose: In order to assess the association of microparticles derived from activated platelets (PMP) or endothelial cells (EMP) with risk markers for recurrent embolic events in patients with symptomatic carotid artery disease, we studied the associations between PMP/EMP and three risk markers: plaque haemorrhage (PH), micro-embolic signals and cerebral diffusion abnormalities.

Methods: Patients with recently symptomatic high-grade carotid artery stenosis (60-99%, 42 patients, 31 men; mean age 75 ± 8 years) and 30 healthy volunteers (HV, 11 men; mean age 56 ± 12 years) were prospectively recruited. Patients were characterised by carotid magnetic resonance imaging (presence of PH [MRI PH]), brain diffusion MRI (cerebral ischaemia [DWI+]) and transcranial Doppler ultrasound (micro-embolic signals [MES+]). Read More

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http://dx.doi.org/10.1159/000495942DOI Listing

Carotid intima-media thickness in chronic obstructive pulmonary disease and survival: A Multicenter Prospective Study.

Clin Respir J 2019 Apr 3. Epub 2019 Apr 3.

Department of Pulmonary Medicine, Selcuk University, Konya, Turkey.

Introduction: Chronic obstructive pulmonary disease (COPD) is associated with increased cardiovascular morbidity and mortality. Carotid intima-media thickness (CIMT) is a non-invasive method assessing atherosclerosis.

Objective: It was aimed to determine relationship and survival between COPD and CIMT. Read More

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http://dx.doi.org/10.1111/crj.13024DOI Listing
April 2019
3 Reads

Risk Factors for Recurrent Carotid-Artery Stenosis Following Stenting Treatment.

Med Sci Monit 2019 Apr 3;25:2429-2434. Epub 2019 Apr 3.

Department of Neurosurgery, Jining No. 1 People's Hospital, Jining, Shandong, China (mainland).

BACKGROUND Carotid artery stenting (CAS) has been regarded as a reliable treatment approach for carotid artery stenosis. However, recurrent carotid artery stenosis after CAS affects long-term outcomes. In this study, we aimed to investigate the potential risk factors for carotid restenosis. Read More

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http://dx.doi.org/10.12659/MSM.913894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459049PMC
April 2019
2 Reads

Carotid stenosis prevalence after radiotherapy in nasopharyngeal carcinoma: A meta-analysis.

Radiother Oncol 2019 Apr 4;133:167-175. Epub 2019 Feb 4.

Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China; Guangdong Province Key Laboratory of Brain Function and Disease, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China; Laboratory of RNA and Major Diseases of Brain and Heart, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. Electronic address:

Purpose: Radiotherapy (RT) is the most effective treatment for nasopharyngeal carcinoma (NPC) but may cause stenosis of the carotid arteries. This meta-analysis evaluates the prevalence of carotid stenosis after radiation therapy.

Materials And Methods: Online search for studies reporting carotid stenosis in patients with NPC who received radiation therapy (RT) compared to NPC patients who did not receive RT and compared to healthy controls. Read More

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http://dx.doi.org/10.1016/j.radonc.2018.11.013DOI Listing
April 2019
2 Reads
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Carotid plaque is a predictor of major adverse cardiac and cerebrovascular events in patients undergoing coronary angiography.

Arch Cardiol Mex 2019 ;89(1):5-11

Department of Cardiology, Hospital Universitario Lucus Augusti (HULA), Lugo, Spain.

Introduction: Carotid disease, measured as carotid intima-media thickness (CIMT) and carotid plaque (CP), is associated with major adverse cardiac and cerebrovascular events (MACCE) in people without the previous atherosclerotic disease; however, there are few published data in patients undergoing coronary angiography. The aim of the study is to determinate if the carotid disease is associated with MACCE after coronary angiography.

Methods: A total of 390 consecutive patients underwent coronary angiography after exercise echocardiography and carotid ultrasonography between 2002 and 2013. Read More

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http://dx.doi.org/10.24875/ACM.M19000015DOI Listing
January 2019
2 Reads

Hemorrhagic occlusive retinal vasculitis leading to the diagnosis of ciliary body melanoma.

Saudi J Ophthalmol 2019 Jan-Mar;33(1):81-83. Epub 2018 Sep 24.

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA.

Hemorrhagic occlusive retinal vasculitis (HORV) is a condition associated with intraocular vancomycin during surgical intervention, most frequently following bilateral sequential cataract surgery. Because of the high rate of ophthalmic vascular complications in this condition, gonioscopic evaluation for identification of neovascularization of the angle and iris is essential. Careful examination can reveal previously asymptomatic and unassociated lesions of the iris or ciliary body. Read More

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http://dx.doi.org/10.1016/j.sjopt.2018.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424716PMC
September 2018
1 Read

Carotid Ultrasound.

Radiol Clin North Am 2019 May 22;57(3):501-518. Epub 2019 Feb 22.

Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, PO Box 208042, New Haven, CT 06520-8042, USA.

Doppler ultrasound (US) is the primary noninvasive imaging modality for detecting, grading, and monitoring extracranial internal carotid artery (ICA) stenosis, which is a well-established surrogate marker for stroke risk. In addition, Doppler US is the primary imaging modality for surveillance of patients following carotid intervention with endarterectomy or stent placement. This article reviews the pathophysiology and epidemiology of stroke, technique for performing a carotid US examination, normal findings, and diagnostic US criteria for evaluating carotid plaque, grading stenosis in the native ICA and following intervention, as well as waveform analysis of the carotid arteries. Read More

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http://dx.doi.org/10.1016/j.rcl.2019.01.008DOI Listing