3,415 results match your criteria Caries Research[Journal]


How to Intervene in the Caries Process in Children: A Joint ORCA and EFCD Expert Delphi Consensus Statement.

Caries Res 2020 Jul 1:1-9. Epub 2020 Jul 1.

Centre de Recherche en Odontologie Clinique EA 4847, UFR d'Odontologie, Département d'Odontologie Conservatrice, Université Clermont Auvergne, Clermont-Ferrand, France.

This paper provides recommendations for dentists for the treatment of dental caries in children, with an emphasis on early childhood caries (ECC), primary teeth, and occlusal surfaces in permanent teeth. A consensus workshop followed by an e-Delphi consensus process was conducted with an expert panel nominated by the European Organization for Caries Research (ORCA) and European Federation of Conservative Dentistry (EFCD)/German Association of Conservative Dentistry (DGZ) boards. Based on 3 systematic reviews and a nonsystematic literature search, recommendations were developed. Read More

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http://dx.doi.org/10.1159/000507692DOI Listing
July 2020
2.281 Impact Factor

Is Fluorescence Technology a Promising Tool for Detecting Infected Dentin in Deep Carious Lesions?

Caries Res 2020 Jun 24:1-13. Epub 2020 Jun 24.

Department of Comprehensive Care, Tufts University School of Dental Medicine, Boston, Massachusetts, USA.

The purpose of this study was to determine if the degree of fluorescence detected by fluorescence-aided caries excavation (FACE) correlates with dentin bacterial microbiome diversity, as assessed by 16S rRNA gene amplicon sequencing, and with traditional tactile dentin caries assessment. Unidentified human teeth were obtained from a dental facility. The included teeth had a carious lesion two-thirds into the dentin, verified by radiography, and were red-fluorescing (RF) using FACE technology (SIROInspect; Sirona, Bensheim, Germany). Read More

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http://dx.doi.org/10.1159/000505643DOI Listing

Assessing the Predictive Performance of Probabilistic Caries Risk Assessment Models: The Importance of Calibration.

Caries Res 2020 Jun 9:1-8. Epub 2020 Jun 9.

Department of Oral and Maxillofacial Sciences, 'Sapienza' University of Rome, Rome, Italy.

Probabilistic caries risk assessment models (P-CRA), such as the Cariogram, are promising tools to planning treatments in order to control and prevent caries. The usefulness of these models for informing patients and medical decision-making depends on 2 properties known as discrimination and calibration. Current common assessment of P-CRA models, however, ignores calibration, and this can be misleading. Read More

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http://dx.doi.org/10.1159/000507276DOI Listing

Amount of Dentifrice and Fluoride Concentration Influence Salivary Fluoride Concentrations and Fluoride Intake by Toddlers.

Caries Res 2020 Jun 9:1-8. Epub 2020 Jun 9.

Department of Preventive and Restorative Dentistry, School of Dentistry, São Paulo State University (UNESP), Araçatuba, Brazil,

The present study evaluated fluoride (F) concentrations in saliva of toddlers after brushing with dentifrices containing different F concentrations, applied in different quantities, and estimated F intake from toothbrushing. The study comprised a double-blind, crossover protocol, in which toddlers (n = 18, 2-3 years old) were randomly assigned into six groups, according to possible combinations of dentifrices (0/550/1,100 ppm F, as NaF) and amounts (rice grain, pea size, and transverse technique). Volunteers used a F-free dentifrice during 1 week. Read More

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http://dx.doi.org/10.1159/000503780DOI Listing

Clinical Consequences of Untreated Dental Caries, Individual Characteristics, and Environmental Factors on Self-Reported Oral Health Measures in Adolescents: A Follow-Up Prevalence Study.

Caries Res 2020 Apr 15:1-9. Epub 2020 Apr 15.

School of Dentistry, Federal University of Amazonas, Manaus, Brazil.

Background/aims: This study evaluated the relationships of clinical consequences of untreated dental caries, individual characteristics, and environmental factors on self-reported oral health measures in adolescents.

Methods: A follow-up prevalence study was conducted involving 406 twelve-year-old adolescents selected from public schools in the eastern area of the city of Manaus, Brazil. Baseline data included clinical consequences of untreated caries (PUFA/pufa index), DMFT, sociodemographic characteristics (sex, parental schooling, and family income), psychosocial factors (sense of coherence [SOC-13 scale], oral health beliefs and self-esteem [Rosenberg Self-Esteem Scale]), and social support (SSA questionnaire). Read More

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http://dx.doi.org/10.1159/000506438DOI Listing

Oral Lactobacilli Related to Caries Status of Children with Primary Dentition.

Caries Res 2020 Apr 1:1-11. Epub 2020 Apr 1.

Department of Pediatric Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

Oral lactobacilli are members of a group of bacteria implicated in caries progression, although information regarding their transmission, colonization, and caries-associated species is not well established. This study isolated oral lactobacilli from a group of children with primary dentition for determination of Lactobacillus prevalence, detection of Streptococcus mutans, a major pathogen of caries initiation, and dental caries status of the children. Species of Lactobacillus isolates were determined from examination of 16S rDNA sequences. Read More

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http://dx.doi.org/10.1159/000506468DOI Listing

Chemically Soluble Fluoride in Na2FPO3/CaCO3-Based Toothpaste as an Indicator of Fluoride Bioavailability in Saliva during and after Toothbrushing.

Caries Res 2020 Mar 26:1-9. Epub 2020 Mar 26.

Piracicaba Dental School, University of Campinas - UNICAMP, Piracicaba, Brazil.

The relationship between the concentration of chemically soluble fluoride found in toothpaste and that present in saliva, during and after brushing, was evaluated as an indicator of potentially bioavailable fluoride in toothpaste. Ten adult participants brushed their teeth with the assigned toothpastes: group I: fresh sample of a fluoride toothpaste: Na2FPO3/CaCO3, 1,378 µg F/g of total soluble fluoride (TSF); groups II-IV: aged samples of toothpaste presenting TSF concentrations of 1,160, 900, and 597 µg F/g, respectively; group V: non-F placebo toothpaste. The volunteers brushed their teeth for 1 min with 0. Read More

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http://dx.doi.org/10.1159/000506439DOI Listing

Relationship between Changes in Chemical Composition of Enamel Subsurface Lesions and the Emitted Nonlinear Optical Signals: An in vitro Study.

Caries Res 2020 Feb 27:1-10. Epub 2020 Feb 27.

Laboratoire Charles Coulomb (L2C), University of Montpellier, CNRS, Montpellier, France.

The development of new diagnostic technologies based on the light scattering and autofluorescence properties of dental tissues is required to improve the diagnostic ability of initial caries lesions earlier than previously done and promoting the potential of treatment without surgical intervention. The aim of this study is to correlate fluorescence-based results provided by multiphoton microscopy (MPM) with confocal Raman microscopy records using phosphate level at 960 cm-1 and the organic matrix at ∼2,931 cm-1 in healthy and demineralized human enamel. Measurements on 14 teeth were made using two incident lights of different wavelengths, released by confocal Raman microscopy and MPM. Read More

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http://dx.doi.org/10.1159/000505904DOI Listing
February 2020

Radiographic Yield for Clinical Caries Diagnosis in Young Adults: Indicators for Radiographic Examination.

Caries Res 2020 Feb 26:1-11. Epub 2020 Feb 26.

Department of Preventive and Social Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.

This prospective cohort study investigated the distribution pattern of carious lesions diagnosed by visual tactile and radiographic examinations, assessed the radiographic yield for clinical caries diagnosis, and estimated how accurately commonly used indicators for caries identified young adults who would benefit from radiographs at different thresholds. Overall, 576 patients aged 16-32 years seeking a first consultation were included. Patients were examined for caries and answered a validated questionnaire on sociodemographics and oral health behavior. Read More

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http://dx.doi.org/10.1159/000505905DOI Listing
February 2020

Aquaporins' Influence on Different Dental Erosive Wear Phenotypes in Humans.

Caries Res 2020 Feb 11:1-11. Epub 2020 Feb 11.

Nordic Institute of Dental Materials, Oslo, Norway.

Dental erosive wear is a multifactorial condition of high prevalence. Nowadays, there is an emphasis on discovering individual genetic predisposition for the development of this condition. Aquaporins (AQPs) are water channel proteins expressed in salivary glands, as well as during tooth development. Read More

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http://dx.doi.org/10.1159/000505965DOI Listing
February 2020

Protective Effect of Fluoride Varnish Containing Trimetaphosphate against Dentin Erosion and Erosion/Abrasion: An in vitro Study.

Caries Res 2020 Jan 22:1-4. Epub 2020 Jan 22.

Department of Pediatric Dentistry and Public Health, School of Dentistry, Araçatuba, São Paulo State University (UNESP), Araçatuba, Brazil,

This in vitro study evaluated the protective effect of fluoride varnishes containing sodium trimetaphosphate (TMP) against dentin erosion and abrasion. Specimens of coronal dentin were divided into: placebo, 2.5% NaF, 5% NaF, 2. Read More

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http://dx.doi.org/10.1159/000505179DOI Listing
January 2020
2.281 Impact Factor

Impact of Clustering Oral Symptoms in the Pathogenesis of Radiation Caries: A Systematic Review.

Caries Res 2020 Jan 21:1-14. Epub 2020 Jan 21.

Oral Diagnosis Department, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, Brazil,

Radiation-related caries (RRC) is a disease with a high potential for destruction of the dentition, which impairs quality of life in head-and-neck (HN) cancer (HNC) patients who undergo radiotherapy. In light of the recently described "clustering of oral symptoms theory," the present systematic review (PROSPERO CRD42019132709) aims to assess HN and gastrointestinal (GI) symptom clusters among HNC patients and discusses how these indirect effects of cancer therapy play a pivotal role in the pathophysiology of RRC. The search was performed at PubMed, Scopus, and Embase and resulted in 11 studies that met the inclusion criteria. Read More

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http://dx.doi.org/10.1159/000504878DOI Listing
January 2020

Biomarkers for the Assessment of Fluoride Exposure in Children.

Caries Res 2020 Jan 21:1-10. Epub 2020 Jan 21.

School of Health and Life Sciences, Teesside University, Middlesbrough, United Kingdom,

Due to practical difficulties in quantifying fluoride exposure, the ability of various biomarkers to predict exposure has been investigated previously. However, the results are inadequate for validation of their application and usefulness. This study aimed to investigate the association between contemporary/recent biomarkers of fluoride exposure and total daily fluoride intake (TDFI) of children with large differences in fluoride exposure through drinking water. Read More

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http://dx.doi.org/10.1159/000504166DOI Listing
January 2020

Differences in the Natural Enamel Surface and Acquired Enamel Pellicle following Exposure to Citric or Hydrochloric Acid.

Caries Res 2020 Jan 21:1-8. Epub 2020 Jan 21.

Centre for Clinical, Oral and Translational Sciences, King's College London Faculty of Dental, Oral and Craniofacial Sciences, London, United Kingdom.

Objectives: The aim of this study was to investigate variations in the interaction between enamel, that is, the acquired enamel pellicle (AEP) and citric or hydrochloric acid.

Materials And Methods: A 24-h AEP was formed on natural enamel specimens (n = 40) from pooled whole mouth human saliva. Samples were randomly allocated to citric (0. Read More

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http://dx.doi.org/10.1159/000504746DOI Listing
January 2020

Prevention of Enamel Softening by Rinsing with a Calcium Solution before Dental Erosion.

Caries Res 2020 Jan 7:1-7. Epub 2020 Jan 7.

Clinic of Preventive Dentistry, Periodontology and Cariology, Center for Dental Medicine, University of Zurich, Zurich, Switzerland.

Objectives: This in situ study aimed to evaluate whether rinsing with a calcium-containing solution prior to an erosive attack reduces the softening of enamel.

Materials And Methods: A total of 240 bovine enamel samples with determined baseline surface microhardness (KHN) were allocated to 5 runs in which each of the 12 volunteers performed the following experiment: 4 enamel samples were inserted in a custom-made intraoral appliance and carried in the mouth (upper jaw) for 30 min before each volunteer either rinsed his mouth for 60 s with a fluoride- and stannous ion-containing dental erosion protection mouth rinse as positive control (run 1), milk (run 2), a solution prepared from a 500-mg calcium effervescent tablet dissolved in 100 mL (run 3) or 200 mL (run 4) water, or did not perform any rinsing with a test solution before the erosive attack (run 5, negative control). To simulate the erosive attack, volunteers rinsed their mouth with a commercial soft drink (Sprite Zero) for 60 s and afterwards with water to stop the erosive process. Read More

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http://dx.doi.org/10.1159/000504747DOI Listing
January 2020

Editorial.

Caries Res 2020 7;54(1). Epub 2020 Jan 7.

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http://dx.doi.org/10.1159/000505319DOI Listing
January 2020

How to Intervene in the Caries Process: Early Childhood Caries - A Systematic Review.

Caries Res 2020 Jan 7:1-11. Epub 2020 Jan 7.

Department of Paediatric and Preventive Dentistry, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.

For an Organisation for Caries Research/European Federation of Conservative Dentistry consensus, this systematic review is aimed to assess the question of how to manage the caries process in the case of early childhood caries (ECC). Medline via PubMed was searched systematically regarding management of ECC. First priority was existing systematic reviews or randomized clinical trials otherwise cohort studies dealing with management of ECC, primarily with carious anterior teeth. Read More

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http://dx.doi.org/10.1159/000504335DOI Listing
January 2020

Effects of the Consumption of Probiotic Yogurt Containing Bifidobacterium lactis Bb12 on the Levels of Streptococcus mutans and Lactobacilli in Saliva of Students with Initial Stages of Dental Caries: A Double-Blind Randomized Controlled Trial.

Caries Res 2020 10;54(1):68-74. Epub 2019 Dec 10.

Nutrition and Metabolic Diseases Research Center and Hyperlipidemia Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran,

Dental caries, caused by oral microbiota, is one of the most common human diseases. The present study aimed to investigate the effect of consumption of probiotic yogurt containing Bifidobacterium lactis Bb12 on salivary Streptococcus mutans and lactobacilli in students with initial stages of dental caries. In this double-blind randomized placebo-controlled clinical trial, 66 students (18-30 years) with initial stages of dental caries were selected and randomly assigned into 2 groups: the intervention group received 300 g/day of probiotic yogurt and the control group received 300 g/day of conventional yogurt for 2 weeks. Read More

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http://dx.doi.org/10.1159/000504164DOI Listing
December 2019
5 Reads

ORCA Announcements.

Authors:

Caries Res 2020 5;54(1):96-98. Epub 2019 Dec 5.

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http://dx.doi.org/10.1159/000505110DOI Listing
December 2019

Is There an Association between Asthma and Dental Caries and Molar Incisor Hypomineralisation?

Caries Res 2020 29;54(1):87-95. Epub 2019 Nov 29.

Department of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilians-Universität München, Munich, Germany,

This epidemiological study aimed to compare the caries and molar incisor hypomineralisation (MIH) experience in asthmatic and non-asthmatic adolescents assessed at 10 and 15 years of age. 730 adolescents from ongoing birth cohort studies (GINIplus/LISA) from Munich, Germany, were examined for carious lesions at the age of 10 and 15 years to determine caries experience under inclusion of non-cavitated carious lesions D1-2T and the tooth-related decay-missing-filled index. Furthermore, MIH was scored on all permanent teeth according to the criteria of the European Academy of Paediatric Dentistry. Read More

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http://dx.doi.org/10.1159/000504382DOI Listing
November 2019

Effects of Dentifrices Differing in Fluoride Content on Remineralization Characteristics of Dentin in vitro.

Caries Res 2020 27;54(1):75-86. Epub 2019 Nov 27.

Department of Operative Dentistry, Periodontology and Preventive Dentistry, RWTH Aachen University, Aachen, Germany.

Objectives: The aim of this study was to compare the caries preventive effect of highly fluoridated dentifrices and gels on sound dentin as well as on artificial dentin caries-like lesions.

Methods: Bovine dentin specimens (n = 240), with 2 different surfaces each (1 sound surface [sound treatment (ST)] and one caries lesion [demineralized treatment (DT)]), were prepared and randomly allocated to one highly (6 × 120 min demineralization/day [H]) and one lowly cariogenic (6 × 60 min demineralization/day [L]) pH-cycling model. Treatments during pH-cycling (28 days) were: brushing 2×/day with: 0 ppm F [H0/L0], 1,450 ppm F [H1,450/L1,450], 2,800 ppm F [H2,800/L2,800], 5,000 ppm F [H5,000/L5,000], 5,000 ppm F plus TCP [H5,000+TCP/L5,000+TCP], and 12,500 ppm F [H12,500/L12,500] containing dentifrices/gels. Read More

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http://dx.doi.org/10.1159/000504165DOI Listing
November 2019

Toward Preventing Enamel Hypoplasia: Modeling Maternal and Neonatal Biomarkers of Human Calcium Homeostasis.

Caries Res 2020 30;54(1):55-67. Epub 2019 Oct 30.

Department of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.

Aim: The aim of this study was to assess biomarkers of calcium homeostasis and tooth development, in mothers during pregnancy and their children at birth, for enamel hypoplasia (EH) in the primary maxillary central incisor teeth.

Methods: Bayesian methodology was used for secondary data analyses from a randomized, controlled trial of prenatal vitamin D3 supplementation in healthy mothers (N = 350) and a follow-up study of a subset of the children. The biomarkers were serum calcium (Ca), phosphorus (P), intact parathyroid hormone (iPTH), total circulating 25-dihydroxyvitamin D (25(OH)D), and 1,25-dihydroxyvitamin D (1,25(OH)2D). Read More

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http://dx.doi.org/10.1159/000502793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299520PMC
October 2019
2.281 Impact Factor

Terminology of Erosive Tooth Wear: Consensus Report of a Workshop Organized by the ORCA and the Cariology Research Group of the IADR.

Caries Res 2020 14;54(1):2-6. Epub 2019 Oct 14.

Department of Cariology, Operative Dentistry and Dental Public Health, Oral Health Research Institute, Indiana University School of Dentistry, Indianapolis, Indiana, USA.

Our understanding of erosive tooth wear and its contributing factors has evolved considerably over the last decades. New terms have been continuously introduced, which frequently describe the same aspects of this condition, whereas other terms are being used inappropriately. This has led to unnecessary confusion and miscommunication between patients, professionals, and researchers. Read More

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http://dx.doi.org/10.1159/000503308DOI Listing
October 2019
2.281 Impact Factor

Terminology of Dental Caries and Dental Caries Management: Consensus Report of a Workshop Organized by ORCA and Cariology Research Group of IADR.

Caries Res 2020 7;54(1):7-14. Epub 2019 Oct 7.

Section of Dental Pathology, Operative Dentistry and Endodontics, Department of Dentistry and Oral Health, University of Aarhus, Aarhus, Denmark.

A 2-day workshop of ORCA and the IADR Cariology Research Group was organized to discuss and reach consensus on definitions of the most commonly used terms in cariology. The aims were to identify and to select the most commonly used terms of dental caries and dental caries management and to define them based on current concepts. Terms related to definition, diagnosis, risk assessment, and monitoring of dental caries were included. Read More

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http://dx.doi.org/10.1159/000503309DOI Listing
October 2019
1 Read

An Experimental Review of Optical Coherence Tomography Systems for Noninvasive Assessment of Hard Dental Tissues.

Caries Res 2020 18;54(1):43-54. Epub 2019 Sep 18.

Department of Biomedical Engineering, Rutgers, the State University of New Jersey, Piscataway, New Jersey, USA,

Optical coherence tomography (OCT) is a noninvasive, high-resolution, cross-sectional imaging technique. To date, OCT has been demonstrated in several areas of dentistry, primarily using wavelengths around 1,300 nm, low numerical aperture (NA) imaging lenses, and detectors insensitive to the polarization of light. The objective of this study is to compare the performance of three commercially available OCT systems operating with alternative wavelengths, imaging lenses, and detectors for OCT imaging of dental enamel. Read More

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http://dx.doi.org/10.1159/000502375DOI Listing
September 2019

T2 Mapping as a Tool for Assessment of Dental Pulp Response to Caries Progression: An in vivo MRI Study.

Caries Res 2020 11;54(1):24-35. Epub 2019 Sep 11.

Institute of Physiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

Among radiological methods, magnetic resonance imaging (MRI) excels in its ability to image soft tissue at great contrast and without the need of harmful radiation. This study tested whether in vivo MRI based on standard MRI sequences run on a standard clinical MRI system can be used to quantify dental pulp response to caries progression using the T2 mapping method. In the study, 74 teeth were scanned on a 3-T MRI system, and caries was assessed according to the International Caries Detection and Assessment System (ICDAS). Read More

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http://dx.doi.org/10.1159/000501901DOI Listing
September 2019
2 Reads

Effects of Bovine Serum Albumin and High pH Pre-Treatment on the Remineralisation of Enamel Subsurface Lesions in vitro.

Caries Res 2020 5;54(1):36-42. Epub 2019 Sep 5.

Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, Melbourne, Victoria, Australia,

Accumulated intra-lesion protein such as serum albumin has been speculated to impede remineralisation of carious enamel lesions. The aim of this study was to assess whether intra-lesion bovine serum albumin (BSA) affected subsequent remineralisation of enamel subsurface lesions. Confocal microscopy was used to confirm localisation of BSA in artificial enamel subsurface lesions and its subsequent degradation by a high pH sodium hypochlorite treatment. Read More

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http://dx.doi.org/10.1159/000502337DOI Listing
September 2019
5 Reads

How to Intervene in the Root Caries Process? Systematic Review and Meta-Analyses.

Caries Res 2019 14;53(6):599-608. Epub 2019 Aug 14.

Cariology Unit, Department of Oral Rehabilitation, University of Talca, Talca, Chile.

The aim of this review as part of the preparation for a workshop organized by the European Federation of Conservative Dentistry (EFCD) in conjunction with the European Organisation for Caries Research (ORCA) was to systematically analyze available evidence of non-, micro- as well as invasive interventions for root caries lesions (RCLs). For each treatment strategy, a separate systematic review was either performed (micro-invasive and choice of restorative material) or updated (non-invasive and excavation technique) each of them following PRISMA guidelines, and if possible meta-analyses were performed. Besides the general advice to improve tooth brushing with fluoride toothpaste main findings for non-invasive interventions in RCLs, the use of dentifrices containing 5,000 ppm F- as well as professionally applied chlorhexidine varnish or silver diamine fluoride seemed to be more efficacious to arrest root caries compared to conventional fluoride toothpaste or placebo respectively. Read More

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http://dx.doi.org/10.1159/000501588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943811PMC
July 2020
1 Read

Do Patients with Extrinsic Black Tooth Stains Have a Lower Dental Caries Experience? A Systematic Review and Meta-Analysis.

Caries Res 2019 7;53(6):617-627. Epub 2019 Aug 7.

Department of Pediatric Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Studies have suggested that individuals affected by extrinsic black tooth stains have less dental caries experience in comparison to those without this condition. The aim of the present study was to perform a systematic review and meta-analysis to determine whether there is scientific evidence demonstrating that extrinsic black stains are a protective factor for the occurrence of dental caries. This systematic review was developed in accordance with the PRISMA statement and the research question was determined using the PECO strategy. Read More

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http://dx.doi.org/10.1159/000500476DOI Listing

Changes in Adolescents' Oral Health Status: Responsiveness of the Child Perception Questionnaire11-14.

Caries Res 2020 30;54(1):15-23. Epub 2019 Jul 30.

Faculty of Medicine and Dentistry, Catholic University of Louvain, Brussels, Belgium,

Changes in oral health status following treatment should be assessed clinically as well as by patients' reported outcomes. This study investigated changes on oral-health-related quality of life (OHRQoL) of adolescents enrolled in a comprehensive oral health care program for caries and gingival conditions. The sensitivity of the Child Perception Questionnaire11-14 (CPQ11-14) to detect clinical changes, that is, its responsiveness, was assessed. Read More

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http://dx.doi.org/10.1159/000501587DOI Listing
July 2019
3 Reads

40-Year Longitudinal Caries Development in German Adolescents in the Light of New Caries Measures.

Caries Res 2019 26;53(6):609-616. Epub 2019 Jul 26.

Department of Preventive and Pediatric Dentistry, University of Greifswald, Greifswald, Germany.

This study assessed the 40-year longitudinal caries development in German adolescents in the light of the sixth National Oral Health Survey in Children (NOHSC, 2016) employing initial DMFT (IDMFT), Significant Caries Index (SiC) and Specific Affected Caries Index (SaC). On the basis of the current NOHSC (randomized cluster selection using school list or regional community school surveys, 55,956 12-year-old sixth-graders examined by 482 calibrated community/study dentists) DMFT, SiC, a novel IDMFT including initial lesions (IT) and the recently introduced SaC were calculated and also recalculated for national and international surveys from the last 4 decades. In 2016, 78. Read More

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http://dx.doi.org/10.1159/000501263DOI Listing
July 2020
5 Reads

Fluoride in Saliva and Oral Mucosa after Brushing with 1,450 or 5,000 ppm Fluoride Toothpaste.

Caries Res 2019 15;53(6):675-681. Epub 2019 Jul 15.

Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark.

The aim was to measure and compare fluoride concentrations in oral mucosa and saliva following a single brushing with either 1,450 or 5,000 ppm fluoride toothpaste. Fourteen healthy participants provided saliva and oral mucosa samples in the morning before tooth brushing. Then participants brushed their teeth with 1,450 ppm fluoride toothpaste, and saliva and mucosa samples were collected after 1, 2, 4, and 6 h. Read More

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http://dx.doi.org/10.1159/000501264DOI Listing

Risk of Dental Caries in Primary Teeth with Developmental Defects of Enamel: A Longitudinal Study with a Multilevel Approach.

Caries Res 2019 10;53(6):667-674. Epub 2019 Jul 10.

Department of Paediatric Dentistry and Orthodontics, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

The risk of dental caries seems to be greater in the presence of developmental defects of enamel (DDE). The aim was to determine whether the presence of DDE in the primary teeth of preschool children increases the risk of dental caries in the primary dentition after a period of approximately 2 years. This study was conducted in two stages: baseline (T0) and follow-up (T1). Read More

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http://dx.doi.org/10.1159/000501029DOI Listing

Responsiveness of Oral Health-Related Quality of Life Questionnaires to Dental Caries Interventions: Systematic Review and Meta-Analysis.

Caries Res 2019 5;53(6):585-598. Epub 2019 Jul 5.

Faculty of Medicine and Dentistry, Catholic University of Louvain (UCL), Brussels, Belgium,

This systematic review and meta-analysis were undertaken to assess the responsiveness of validated oral health-related quality of life (OHRQoL) questionnaires to dental caries interventions in children, adolescents, and young adults. Studies eligible were randomized clinical trials (RCTs), controlled clinical trials (CCTs), and prospective case series (PCS), which had OHRQoL questionnaires answered before and after caries intervention(s). The main outcome was improvement in OHRQoL mean scores following caries intervention. Read More

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http://dx.doi.org/10.1159/000500855DOI Listing

Fluoride Varnish and Dental Caries in Preschoolers: A Systematic Review and Meta-Analysis.

Caries Res 2019 20;53(5):502-513. Epub 2019 Jun 20.

Department of Community and Preventive Dentistry, School of Dentistry, Rio de Janeiro State University, Rio de Janeiro, Brazil.

The aim of this study was to assess the effectiveness of fluoride varnish (FV) in reducing dentine caries at the patient, tooth, and surface levels as well as caries-related hospitalizations in preschoolers. We performed a systematic review of clinical trials of FV, alone or associated with an oral health program, compared with placebo, usual care, or no intervention. Bibliographical search included electronic searches of seven databases, registers of ongoing trials, and meeting abstracts, as well as hand searching. Read More

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http://dx.doi.org/10.1159/000499639DOI Listing
July 2020
4 Reads

Caries Trends in the Primary Dentition of 6- to 7-Year-old Schoolchildren in Germany from 1994 to 2016: Results from the German National Oral Health Surveys in Children.

Caries Res 2019 13;53(6):659-666. Epub 2019 Jun 13.

Department of Preventive and Pediatric Dentistry, University of Greifswald, Greifswald, Germany.

Long-term nationally representative caries data in the primary dentition are rare, but nonetheless central to assess needs in caries prevention and treatment. This study evaluated the prevalence and trends of caries levels in the primary dentition of 6- to 7-year-olds in Germany as a whole and its federal states individually. In 2016, employing a randomized cluster selection, 6- to 7-year-old first graders were included in the National German Oral Health Survey performed regularly since 1994/95. Read More

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http://dx.doi.org/10.1159/000500854DOI Listing
July 2020
3 Reads

Developing and Testing Electronic Health Record-Derived Caries Indices.

Caries Res 2019 5;53(6):650-658. Epub 2019 Jun 5.

Department of Preventive and Restorative Dental Sciences, University of California, San Francisco, San Francisco, California, USA.

Caries indices, the basis of epidemiologic caries measures, are not easily obtained in clinical settings. This study's objective was to design, test, and validate an automated program (Valid Electronic Health Record Dental Caries Indices Calculator Tool [VERDICT]) to calculate caries indices from an electronic health record (EHR). Synthetic use case scenarios and actual patient cases of primary, mixed, and permanent dentition, including decayed, missing, and filled teeth (DMFT/dmft) and tooth surfaces (DMFS/dmfs) were entered into the EHR. Read More

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http://dx.doi.org/10.1159/000499700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864222PMC
July 2020
11 Reads

Erosion-Protective Capacity of the Salivary Pellicle of Female and Male Subjects Is Not Different.

Caries Res 2019 4;53(6):636-642. Epub 2019 Jun 4.

Department of Preventive Dentistry, Periodontology and Cariology, University Medical Center Göttingen, Göttingen, Germany.

This study aimed to analyse if the erosion-protective potential of the salivary pellicle is different between female and male subjects. Bovine enamel and dentin specimens (each n = 3) were exposed to the oral cavity of healthy female or male volunteers (each n = 25, females: 25.8 ± 3. Read More

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http://dx.doi.org/10.1159/000500046DOI Listing
July 2020
15 Reads
2.281 Impact Factor

Casein Phosphopeptide-Amorphous Calcium Phosphate Attenuates Virulence and Modulates Microbial Ecology of Saliva-Derived Polymicrobial Biofilms.

Caries Res 2019 4;53(6):643-649. Epub 2019 Jun 4.

The University of Queensland School of Dentistry, Brisbane, Queensland, Australia.

Background: Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) acts as a salivary biomimetic that provides bioavailable calcium and phosphate ions to augment fluoride-mediated remineralisation of early caries lesions. However, there are indications that it may also have beneficial ecological effects on the oral microbiome.

Objective: This in vitro study investigated whether CPP-ACP could influence microbial counts, acidogenicity, and the relative abundance of specific caries- and health-associated bacterial -species in polymicrobial biofilms. Read More

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http://dx.doi.org/10.1159/000499869DOI Listing
July 2020
3 Reads

Effect of Silver Diamine Fluoride Treatment on Microbial Profiles of Plaque Biofilms from Root/Cervical Caries Lesions.

Caries Res 2019 28;53(5):555-566. Epub 2019 May 28.

Department of Cariology, Restorative Sciences, and Endodontics, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.

Purpose: To assess the effect of silver diamine fluoride (SDF) on microbial profiles present in plaque from root/cervical carious lesions, and its association with caries lesion arrest.

Materials And Methods: Twenty patients with at least one soft cavitated root/cervical carious lesion were included. One lesion/patient was randomly selected and treated with 38% SDF. Read More

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https://www.karger.com/Article/FullText/499578
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http://dx.doi.org/10.1159/000499578DOI Listing
July 2020
27 Reads

Improving Toothbrushing with a Smartphone App: Results of a Randomized Controlled Trial.

Caries Res 2019 27;53(6):628-635. Epub 2019 May 27.

Department of Preventive and Pediatric Dentistry, University of Greifswald, Greifswald, Germany.

Objectives: Performing proper toothbrushing is a complicated process for children. Therefore, the aim of this study was to investigate the effect of a smartphone app for improving manual toothbrushing via a gravitation sensor.

Methods: In this prospective, controlled, single-blinded, randomized clinical trial, 49 children (mean age 5. Read More

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http://dx.doi.org/10.1159/000499868DOI Listing
July 2020
1 Read

Overall Effects of Risk Factors Associated with Dental Caries Indices Using the Marginalized Zero-Inflated Negative Binomial Model.

Caries Res 2019 22;53(5):541-546. Epub 2019 May 22.

Department of Community Oral Health, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

The purpose of this paper is to identify risk factors for decayed, missing, and filled permanent teeth (DMFT) in a population of 12-15-year-old schoolchildren and to apply the marginalized zero-inflated negative binomial (MZINB) model for determination and estimation of the overall effects of the risk factors. A cross-sectional survey comprising 764 students aged between 12 and 15 years was used to analyze the association between caries in children and some background characteristics in children and their parents. Information on the samples' social, behavioral, and demographic status was obtained through a series of closed questions. Read More

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https://www.karger.com/Article/FullText/498892
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http://dx.doi.org/10.1159/000498892DOI Listing
July 2020
10 Reads
2.281 Impact Factor

Fluoride Dentifrice Overcomes the Lower Resistance of Fluorotic Enamel to Demineralization.

Caries Res 2019 21;53(5):567-575. Epub 2019 May 21.

Piracicaba Dental School, University of Campinas, Piracicaba, Brazil,

We evaluated if the low resistance of fluorotic enamel to demineralization could be overcome by fluoride dentifrice (FD) treatment. Paired enamel slabs of sound and fluorotic enamel (n = 20/group) from human teeth presenting Thylstrup and Fejerskov index (TF) scores from 0 to 4 were obtained. Half of the anatomic surface of the enamel slabs was isolated and used as a control (baseline) regarding enamel mineralization and fluoride concentration. Read More

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http://dx.doi.org/10.1159/000499668DOI Listing
July 2020
4 Reads

66th ORCA Congress. Cartagena, Colombia, 3-6 July, 2019.

Authors:

Caries Res 2019 21;53(4):357-410. Epub 2019 May 21.

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http://dx.doi.org/10.1159/000499894DOI Listing

Effect of Different Liners on Pulpal Outcome after Partial Caries Removal: A Preliminary 12 Months Randomised Controlled Trial.

Caries Res 2019 16;53(5):547-554. Epub 2019 May 16.

Department of Conservative Dentistry and Endodontics, Post Graduate Institute of Dental Sciences, Rohtak, India.

Aim: The aim of this double-blinded parallel randomised controlled trial was to compare the effect of different liners on 12-month pulp health outcomes after partial caries removal (PCR) with composite restorations in permanent molars.

Methods: The study was registered at clinicaltrials.gov with registration No. Read More

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http://dx.doi.org/10.1159/000499131DOI Listing
July 2020
4 Reads

Protective Effect of 4% Titanium Tetrafluoride Varnish on Dentin Demineralization Using a Microcosm Biofilm Model.

Caries Res 2019 14;53(5):576-583. Epub 2019 May 14.

Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil,

This study evaluated the effect of titanium tetrafluoride (TiF4) varnish on the development of dentin carious lesions. Bovine root dentin samples were treated for 6 h with: (A) 4% TiF4 varnish (2.45% F); (B) 5. Read More

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http://dx.doi.org/10.1159/000499317DOI Listing
July 2020
3 Reads

Acquired Enamel Pellicle Modification with Casein and Mucin in Different Concentrations and its Impact on Initial Dental Erosion.

Caries Res 2019 14;53(4):457-466. Epub 2019 May 14.

Department of Restorative, Preventive and Pediatric Dentistry, University of Bern, Bern, Switzerland.

Casein and mucin have been shown to improve the erosion-protective properties of the pellicle when applied in combination. The aim of this in vitro study was to optimize the concentrations of these 2 proteins to achieve a maximum protective effect. For the 2 parts of this study, we prepared a total of 195 human enamel specimens and randomly assigned them to 13 groups, corresponding to 11 different casein-mucin concentration-combinations tested and 2 negative control groups (humid chamber). Read More

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http://dx.doi.org/10.1159/000499579DOI Listing
July 2020
7 Reads

Oral and Systemic Effects of Xylitol Consumption.

Caries Res 2019 6;53(5):491-501. Epub 2019 May 6.

Department of Oral and Maxillofacial Diseases, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Recent results of randomized trials testing the efficacy of xylitol in caries prevention have been conflicting. This narrative review reveals the sources of discrepancy. The following databases were searched for the terms "xylitol" or "artificial sweeteners" restricted to the English language: PubMed, Web of Science, Evidenced-Based Medicine, Scopus, and the Cochrane database. Read More

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http://dx.doi.org/10.1159/000499194DOI Listing
July 2020
3 Reads

Critical Appraisal of Oral Pre- and Probiotics for Caries Prevention and Care.

Caries Res 2019 4;53(5):514-526. Epub 2019 Apr 4.

Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark,

In recent years, the concept of preventing caries-related microbial dysbiosis by enhancing the growth and survival of health-associated oral microbiota has emerged. In this article, the current evidence for the role of oral pre- and probiotics in caries prevention and caries management is discussed. Prebiotics are defined as "substrates that are selectively utilized by host microorganisms conferring a health benefit. Read More

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http://dx.doi.org/10.1159/000499037DOI Listing
July 2020
3 Reads

On the Variable Clinical Presentation of Molar-Incisor Hypomineralization.

Caries Res 2019 3;53(4):482-488. Epub 2019 Apr 3.

Melbourne Dental School, University of Melbourne, Melbourne, Victoria, Australia.

Molar-incisor hypomineralization (MIH) is a condition that is defined based on its peculiar clinical presentation. Original reports on the etiology of the condition and possible risk factors were inconclusive, and we refuted the original suggestion that MIH is an idiopathic condition and suggested that MIH has complex inheritance and is due to the interaction of more than one gene and the environment. Our group was the first to suggest MIH has a genetic component that involves genetic variation in genes expressed during dental enamel formation. Read More

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https://www.karger.com/Article/FullText/496542
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http://dx.doi.org/10.1159/000496542DOI Listing
July 2020
7 Reads