60,198 results match your criteria Career Development International[Journal]


Medical student burnout: Impact of the gap year in burnout prevention.

Work 2020 Jul 1. Epub 2020 Jul 1.

Department of Orthopaedic Surgery, Warren Alpert Medical School of Brown University, Providence, RI, USA.

Objective: Burnout is a common response to stress and is pervasive among medical students. An increasing proportion of students are taking "gap years" following undergraduate education and before matriculation to medical school. This study evaluates rates of and risk factors for burnout, with a particular focus on students who took gap years. Read More

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http://dx.doi.org/10.3233/WOR-203203DOI Listing

A Novel Paradigm for Expert Core Facility Staff Training.

Trends Cell Biol 2020 Jul 1. Epub 2020 Jul 1.

Nikon Imaging Center at Harvard Medical School, Boston, MA, USA. Electronic address:

Scientific research relies on a range of technologies, many of which are developing at a fast pace. Technical experts able to advise researchers on experimental design and validate the performance1 of shared instruments are increasingly recognized as critical members of the research community. Here I describe a novel postdoctoral fellowship program designed to train expert imaging scientists, which could easily be adapted for other technologies. Read More

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http://dx.doi.org/10.1016/j.tcb.2020.06.001DOI Listing

Changes in beliefs during driver training and their association with risky driving.

Accid Anal Prev 2020 Jun 30;144:105583. Epub 2020 Jun 30.

Klaipeda University,Klaipeda State University of Applied Sciences, Klaipeda, Lithuania.

Objective: Researchers continue to seek reasons for novice drivers' over-representation in crashes. Evidence on how early interventions might mitigate this global phenomenon remains inconclusive. This study explores changes in novice drivers' beliefs during pre-licensure training and within their first one-year independent provisional license period, and how these changes might help to predict subsequent risky driving. Read More

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http://dx.doi.org/10.1016/j.aap.2020.105583DOI Listing

A structured approach to career mobility and development for new practitioners.

Am J Health Syst Pharm 2020 Jul 4. Epub 2020 Jul 4.

Fisch College of Pharmacy The University of Texas at Tyler Tyler, TX.

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http://dx.doi.org/10.1093/ajhp/zxaa145DOI Listing

What should be included in web-based simulation for new nurses?

Nurse Educ Today 2020 Jun 20;92:104508. Epub 2020 Jun 20.

College of Nursing, Ewha Womans University, Seoul, Republic of Korea. Electronic address:

Purpose: The purpose of this study was to investigate newly graduated nurses' educational needs for web-based simulation (WBS) education.

Methods: A cross-sectional descriptive study was conducted with 132 registered nurses, regardless of their career length, working at a hospital in Korea. Data accrued through a self-reported questionnaire asking nurses about their educational needs. Read More

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http://dx.doi.org/10.1016/j.nedt.2020.104508DOI Listing

HOW FULL IS YOUR TANK? A QUALITATIVE EXPLORATION OF FACULTY VOLUNTEERISM IN A NATIONAL PROFESSIONAL DEVELOPMENT PROGRAM.

Acad Pediatr 2020 Jun 30. Epub 2020 Jun 30.

Department of Pediatrics University of Colorado School of Medicine, Mail Stop B158, Children's Hospital Colorado, 13123 East 16th Avenue, Aurora, Colorado, USA, 80045. Electronic address:

Objective: Professional development programs (PDPs) within academic professional organizations rely on faculty volunteers, but little is known about the volunteering process and experience. Our aim was to gain insights into the initial decision to volunteer, the experience of volunteering and the decision to re-volunteer or not (i.e. Read More

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http://dx.doi.org/10.1016/j.acap.2020.06.140DOI Listing

Introductions to the Community: Early-Career Researchers in the Time of COVID-19.

Authors:

Cell Stem Cell 2020 Jul;27(1):13-14

COVID-19 has unfortunately halted lab work, conferences, and in-person networking, which is especially detrimental to researchers just starting their labs. Through social media and our reviewer networks, we met some early-career stem cell investigators impacted by the closures. Here, they introduce themselves and their research to our readers. Read More

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http://dx.doi.org/10.1016/j.stem.2020.06.011DOI Listing

Exploring stories of learning and professional development: interactions between GP personal tutors and medical students.

Educ Prim Care 2020 Jul 3:1-7. Epub 2020 Jul 3.

Department of Primary care and population health, UCL , London, UK.

Background: The demanding environment at medical school results in some students being prone to a high risk of mental health issues. GMC recommendations include positioning personal tutors for pastoral support and to act as academic role models. Tutors who are clinicians, such as GPs, could help students develop their academic and professional narratives. Read More

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http://dx.doi.org/10.1080/14739879.2020.1786467DOI Listing

Predicting Mental Health and Psychological Wellbeing in Mothers of Children with Autism Spectrum Disorder: Roles of Intolerance of Uncertainty and Coping.

Autism Res 2020 Jul 3. Epub 2020 Jul 3.

Wales Autism Research Centre, School of Psychology, Cardiff University, Cardiff, UK.

Research has consistently shown that parents of children with autism spectrum disorder (ASD) are more likely to report chronic stress and symptoms of psychopathology when compared to parents of typically developing children and children with other psychological or physical conditions. Certain individual characteristics might either put parents at risk or allow them to cope more effectively under the strenuous conditions of raising children with neurodevelopmental conditions. Previous research has suggested that higher levels of intolerance of uncertainty and certain coping styles are associated with higher parental levels of anxiety and depression. Read More

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http://dx.doi.org/10.1002/aur.2341DOI Listing

A Case Report: Insulinoma in a Military Pilot Detected by 68Ga-Dotatate PET/CT.

Mil Med 2020 Jul 3. Epub 2020 Jul 3.

Department of Endocrinology, San Antonio Military Medical Center, 3551 Roger Brooke Dr, San Antonio, TX 78219.

A 37-year-old active duty male Air Force instructor pilot, with no prior medical history, was found unresponsive at his home after awakening with symptoms of altered mental status when the Emergency Medical Service (EMS) was called. The patient was found to be hypoglycemic with a glucose of 37 mg/dL. The patient recovered after administration of a dextrose bolus. Read More

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http://dx.doi.org/10.1093/milmed/usaa100DOI Listing

Attitudes towards medical artificial intelligence talent cultivation: an online survey study.

Ann Transl Med 2020 Jun;8(11):708

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

Background: To investigate the attitude and formal suggestions on talent cultivation in the field of medical artificial intelligence (AI).

Methods: An electronic questionnaire was sent to both medical-related field or non-medical field population using the WenJuanXing web-application via social media. The questionnaire was designed to collect: (I) demographic information; (II) perception of medical AI; (III) willingness to participate in the medical AI related teaching activities; (IV) teaching content of medical AI; (V) the role of medical AI teaching; (VI) future career planning. Read More

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http://dx.doi.org/10.21037/atm.2019.12.149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327345PMC

Teaching clinicians practical genomic medicine: 7 years' experience in a tertiary care center.

Genet Med 2020 Jul 3. Epub 2020 Jul 3.

Recanati Genetic Institute, Rabin Medical Center-Beilinson Hospital, Petach Tikva, Israel.

Purpose: Increased implementation of complex genetic technologies in clinical practice emphasizes the urgency of genomic literacy and proficiency for medical professionals. We evaluated our genomic education model.

Methods: We assessed the 5-day, extended format program, encompassing lectures, videos, interactive tests, practice cases, and clinical exercises. Read More

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http://dx.doi.org/10.1038/s41436-020-0868-4DOI Listing

Strategies for Provider Well-Being in the Emergency Department.

Emerg Med Clin North Am 2020 Aug 8;38(3):729-738. Epub 2020 Jun 8.

Department of Emergency Medicine, Maimonides Medical Center, Brooklyn, NY, USA.

A variety of operational and administrative factors have the potential to decrease wellness and negatively impact emergency physicians, in terms of both their on-the-job performance and their long-term career satisfaction. Among these are the issues of workload balance, physiologic and circadian stresses, and larger issues of malpractice risk and institutional support. This overview covers both emerging research on how these problems affect emergency physicians and strategies to help mitigate these challenges. Read More

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http://dx.doi.org/10.1016/j.emc.2020.03.005DOI Listing

Reflections on the Fellows-in-Training and Early Career Section: Passing the Torch.

J Am Coll Cardiol 2020 Jul;76(1):118-121

Inova Heart and Vascular Institute, Inova Fairfax Medical Center, Falls Church, Virginia.

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http://dx.doi.org/10.1016/j.jacc.2020.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324094PMC

Top tips for interprofessional education and collaborative practice research: a guide for students and early career researchers.

J Interprof Care 2020 Jul 2:1-6. Epub 2020 Jul 2.

AKM-STATS , Scotland, Oxford, UK.

Interprofessional research within the contexts of education and health and social care practice has grown exponentially within the past three decades. To maintain the momentum of high-quality research, it is important that early career researchers embarking on their first research journey and new to interprofessional education or interprofessional collaborative practice feel supported in making their contribution to the field. This guide, developed by the Center for the Advancement of Interprofessional Education (CAIPE) Research Group, has been written with these groups in mind who are embarking on their first research journey, and new to the interprofessional field. Read More

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http://dx.doi.org/10.1080/13561820.2020.1777092DOI Listing

Does 'Fear of COVID-19' trigger future career anxiety? An empirical investigation considering depression from COVID-19 as a mediator.

Int J Soc Psychiatry 2020 Jul 2:20764020935488. Epub 2020 Jul 2.

Department of Business Administration, North Western University, Khulna, Bangladesh.

Background: Due to the outbreak of COVID-19, the mental health of the people all around the world is severely disrupted.

Aim: The purpose of this study is to identify whether 'Fear of COVID-19' impacted on future workforces' career anxiety at the first place and whether depression from COVID-19 has any indirect effect on 'Fear of COVID-19' and future workforces' career anxiety.

Method: Based on three different scales related to 'Fear of COVID-19', depression and career anxiety, a structured questionnaire was developed and the survey data was collected for this study. Read More

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http://dx.doi.org/10.1177/0020764020935488DOI Listing

Skeletal muscle microvascular insulin resistance in type 2 diabetes is not improved by eight weeks of regular walking.

J Appl Physiol (1985) 2020 Jul 2. Epub 2020 Jul 2.

Department of Nutrition and Exercise Physiology, University of Missouri, United States.

We aimed to examine if individuals with type 2 diabetes (T2D) exhibit suppressed leg vascular conductance and skeletal muscle capillary perfusion in response to a hyperinsulinemic-euglycemic clamp, and to test whether these two variables are positively correlated. Subsequently, we examined if T2D-associated skeletal muscle microvascular insulin resistance, as well as overall vascular dysfunction, would be ameliorated by an eight-week walking intervention (45 minutes at 60% of heart rate reserve, 5 sessions/week). We report that, relative to healthy subjects, overweight and obese individuals with T2D exhibit depressed insulin-stimulated increases in leg vascular conductance, skeletal muscle capillary perfusion, and Akt phosphorylation. Read More

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http://dx.doi.org/10.1152/japplphysiol.00174.2020DOI Listing

Self-supervised learning of physics-guided reconstruction neural networks without fully sampled reference data.

Magn Reson Med 2020 Jul 2. Epub 2020 Jul 2.

Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota, USA.

Purpose: To develop a strategy for training a physics-guided MRI reconstruction neural network without a database of fully sampled data sets.

Methods: Self-supervised learning via data undersampling (SSDU) for physics-guided deep learning reconstruction partitions available measurements into two disjoint sets, one of which is used in the data consistency (DC) units in the unrolled network and the other is used to define the loss for training. The proposed training without fully sampled data is compared with fully supervised training with ground-truth data, as well as conventional compressed-sensing and parallel imaging methods using the publicly available fastMRI knee database. Read More

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http://dx.doi.org/10.1002/mrm.28378DOI Listing

Tips for Navigating the Academic Job Market.

Authors:
Darrell Hudson

Health Promot Pract 2020 Jul 2:1524839920938802. Epub 2020 Jul 2.

Brown School at Washington University in St. Louis, MO, USA.

There are many unwritten rules in the academy, and much of the advice that doctoral students receive about the academic job search is from their mentors. For many doctoral students, navigating the academic job market can be bewildering. In this article, an associate professor of public health with experience navigating the job market as well as experience on numerous job search committees provides tips on preparing for and navigating the esoteric academic job market for early career professionals seeking academic faculty positions. Read More

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http://dx.doi.org/10.1177/1524839920938802DOI Listing

Introduction to a special issue on kidney development and disease.

Anat Rec (Hoboken) 2020 Jul 2. Epub 2020 Jul 2.

Department of Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.

Enriching our understanding of the anatomy of the kidneys, in development, health, and disease, has been the primary focus of Professor John Bertram's distinguished research career to date. Among other notable achievements, his landmark analyses of nephron number in over 400 human kidneys (the Monash Series), and his refinement of stereological techniques for renal structural analyses, have proven him an international leader in renal anatomy research. In this Special Issue, we (some of John's collaborators, colleagues, and former students) celebrate John's career with a series of 20 review and original research articles relevant to his expertise: (a) renal anatomy, physiology, and pathology, (b) kidney development, podocyte biology, and applications of renal stem cells, (c) renal developmental programming, and (d) contemporary methodologies in renal research; his accomplishments as a Head (Chair) of an Anatomy Department are also illustrated. Read More

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http://dx.doi.org/10.1002/ar.24467DOI Listing

Scholarship for Social Change: Reflections of an Accidental Academic.

Authors:
Meg A Bond

Am J Community Psychol 2020 Jul 2. Epub 2020 Jul 2.

University of Massachusetts Lowell, Lowell, MA, USA.

In this article, I describe how I stumbled my way into an academic career doing research to promote social change toward greater equity and inclusion. I reflect on how my path has been informed by my own experiences with harassment, marginalization, and privilege. These reflections build upon the belief that we are all informed by our histories, vantage points, and social locations and that those forces shape the questions we ask, the way we ask them, how and where we look for evidence, and what we do with the results once we get them. Read More

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http://dx.doi.org/10.1002/ajcp.12440DOI Listing

Radiation therapy technologists' involvement and opinion in research: A national survey in Italy.

Tech Innov Patient Support Radiat Oncol 2020 Sep 20;15:11-14. Epub 2020 Jun 20.

Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.

Introduction: This survey describes Italian RTTs' involvement and opinions in research activities related to radiation oncology. Primary aim was to assess the degree of involvement of the national RTTs community in research and to describe how RTTs can integrate their skills collaborating with other professionals.

Materials And Methods: A ten-items multiple-choice questionnaire, with 2-8 possible responses, was developed by a steering committee and generated on a survey platform. Read More

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http://dx.doi.org/10.1016/j.tipsro.2020.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322338PMC
September 2020

Feasibility of a smartphone app to enhance physical activity in progressive MS: a pilot randomized controlled pilot trial over three months.

PeerJ 2020 23;8:e9303. Epub 2020 Jun 23.

Institute of Neuroimmunology and Multiple Sclerosis (INIMS), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Background: People with chronic progressive multiple sclerosis (CPMS) have limited options in medical treatment. Enhancing physical activity (PA) might promote neuroregeneration in multiple sclerosis (MS) and positively influence disability, thus providing an alternative to medical treatment. Previous studies indicate that evidence-based patient information (EBPI) is essential for inducing behavioral change, e. Read More

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http://dx.doi.org/10.7717/peerj.9303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319035PMC

Modeling, state estimation, and optimal control for the US COVID-19 outbreak.

Sci Rep 2020 Jul 1;10(1):10711. Epub 2020 Jul 1.

McKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, USA.

The novel coronavirus SARS-CoV-2 and resulting COVID-19 disease have had an unprecedented spread and continue to cause an increasing number of fatalities worldwide. While vaccines are still under development, social distancing, extensive testing, and quarantining of confirmed infected subjects remain the most effective measures to contain the pandemic. These measures carry a significant socioeconomic cost. Read More

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http://dx.doi.org/10.1038/s41598-020-67459-8DOI Listing

Transnational Networks' Contribution to Health Policy Diffusion: A Mixed Method Study of the PerformanceBased Financing Community of Practice in Africa.

Int J Health Policy Manag 2020 Apr 27. Epub 2020 Apr 27.

CEPED (IRD-Université de Paris), Université de Paris, ERL INSERM SAGESUD, Paris, France.

Background: Transnational networks such as Communities of Practice (CoPs) are flourishing, yet their role in diffusing health systems reforms has been seldom investigated. Over the past decade, performance-based financing (PBF) has rapidly spread in Africa. This study explores how, through the PBF Community of Practice's attributes, structure, and strategies, PBF diffusion was fostered in sub-Saharan Africa (SSA). Read More

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http://dx.doi.org/10.34172/ijhpm.2020.57DOI Listing

Doctor Retention: A Cross-sectional Study of How Ireland Has Been Losing the Battle.

Int J Health Policy Manag 2020 Apr 22. Epub 2020 Apr 22.

Department of Mathematics & Statistics, University of Limerick, Limerick, Ireland.

Background: The failure of some high-income countries to retain their medical graduates is one driver of doctor immigration from low- and middle-income countries. Ireland, which attracts many international medical graduates, implemented a doctor retention strategy from early 2015. This study measures junior doctors' migration intentions, the reasons they leave and likelihood of them returning. Read More

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http://dx.doi.org/10.34172/ijhpm.2020.54DOI Listing

The Rise of the Consucrat.

Authors:
Evelyne de Leeuw

Int J Health Policy Manag 2020 Mar 14. Epub 2020 Mar 14.

Centre for Health Equity, Training and Evaluation CHETRE, University of New South Wales, South Western Sydney Local Health District and Ingham Institute, Sydney, NSW, Australia.

Some agents representing the 'receiving end' of the medical-industrial complex could be called 'career consumers.' We identify these consucrats as a new class of intersectional representation of 'those affected' in healthcare delivery systems. We describe them in the context of (similar) abocrats and femocrats but show that consucrats face more complex and different level intersectional challenges. Read More

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http://dx.doi.org/10.34172/ijhpm.2020.36DOI Listing

The Effects of Timing of a Leucine-Enriched Amino Acid Supplement on Body Composition and Physical Function in Stroke Patients: A Randomized Controlled Trial.

Nutrients 2020 Jun 29;12(7). Epub 2020 Jun 29.

Department of Rehabilitation Medicine, Showa University Fujigaoka Rehabilitation Hospital, 2-1-1, Aoba ward, Yokohama, Kanagawa 236-0001, Japan.

The combination of exercise and nutritional intervention is widely used for stroke patients, as well as frail or sarcopenic older persons. As previously shown, supplemental branched chain amino acids (BCAAs) or protein to gain muscle mass has usually been given just after exercise. This study investigated the effect of the timing of supplemental BCAAs with exercise intervention on physical function in stroke patients. Read More

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http://dx.doi.org/10.3390/nu12071928DOI Listing

Increased Pain Reporting by Head and Neck Cancer Patients at Radiation Oncology Consultation: A Quality-of-Life Analysis.

Laryngoscope 2020 Jul 1. Epub 2020 Jul 1.

Department of Radiation Oncology, University of Cincinnati, Cincinnati, Ohio, U.S.A.

Objectives: Head and neck cancers (HNC) are associated with significant morbidity. Quality-of-life (QoL) analyses can assist with understanding subjective factors shaping the patient experience. Here, we assess for patient and/or tumor factors associated with increased pain reporting at the time of initial radiation oncology consultation at a single institution in 2015. Read More

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http://dx.doi.org/10.1002/lary.28784DOI Listing

Prevalence of sports injuries in Korean fencers aged 14-40 years.

J Sports Med Phys Fitness 2020 Jun 30. Epub 2020 Jun 30.

Center for Sport Science in Jeju, Jeju Special Self- Governing Provincial Sports Council, Jeju, Korea -

Background: Although sites and types of injury frequently occurring in fencers have been well described, the type of injury caused by the use of fencing movements is still unknown. This study aimed to provide basic data for injury prevention by understanding the sports injury status in fencers.

Methods: A total of 584 Korean fencers were included in the survey and were classified according to the injured site, cause of injury, and movement that causes injury. Read More

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http://dx.doi.org/10.23736/S0022-4707.20.10900-9DOI Listing

The Dance of Cystic Fibrosis: Experiences of Living with Cystic Fibrosis as an Adult.

J Clin Nurs 2020 Jul 1. Epub 2020 Jul 1.

South Dakota State University College of Nursing, Rapid City, SD, USA.

Aim: This study sought to understand the experience of living with cystic fibrosis as an adult.

Background: Cystic fibrosis is one of the most difficult chronic diseases to manage long-term because of numerous challenges faced on a day-to-day basis. The majority of studies focus on improving symptom response to new treatment regimens with the hope of prolonging life. Read More

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http://dx.doi.org/10.1111/jocn.15397DOI Listing

Shaping the future of physiology.

J Physiol 2020 Jul;598(13):2511-2512

University of Strathclyde, Glasgow, UK.

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http://dx.doi.org/10.1113/JP280152DOI Listing

Biomedical research in developing countries: Opportunities, methods, and challenges.

Indian J Gastroenterol 2020 Jun 30. Epub 2020 Jun 30.

Department of Surgery and Cancer, Imperial College London, South Kensington, London, SW7 2BU, UK.

Health research is essential for improving global health, health equity, and economic development. There are vast differences in the disease burden, research budget allocation, and scientific publications between the developed and the low-middle-income countries, which are the homes of 85% of the world's population. There are multiple challenges, as well as opportunities for health research in developing countries. Read More

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http://dx.doi.org/10.1007/s12664-020-01056-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325473PMC

Challenging Precedent: Critical Care Nursing and Medical Product Innovation.

Authors:
Karen K Giuliano

Am J Crit Care 2020 Jul;29(4):253-261

About the Author: Karen K. Giuliano is an associate professor, College of Nursing and Institute for Applied Life Sciences, University of Massachusetts, Amherst and a consulting nurse scientist, Center for Nursing Research and Advanced Practice, Orlando Health, Orlando, Florida.

In this presentation, I will share my unconventional journey, starting from my first job as a critical care staff nurse to my current role as tenure-track faculty at the University of Massachusetts Amherst, where I hold a joint position with the Institute for Applied Life Sciences and the College of Nursing. Throughout this journey, I have had many opportunities to participate in interdisciplinary clinical outcomes research and medical product development as a staff nurse, clinical nurse specialist, and project lead from the clinical, industry, and academic perspectives. While passionate about my central clinical research interests in technology innovation and its responsible use in critical and acute care, the foundation of my approach is dedicated to the values and lessons of my earliest experiences in critical care bedside nursing: supporting and preserving the dignity and humanity of person-centered patient care. Read More

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http://dx.doi.org/10.4037/ajcc2020275DOI Listing

Support Group Participation: Effect on Perceptions of Patients with Newly Diagnosed Multiple Sclerosis.

Int J MS Care 2020 May-Jun;22(3):115-121. Epub 2019 Oct 8.

Background: Patients newly diagnosed as having multiple sclerosis (MS) face an overwhelming number of questions about how it will affect their lives. Participation in a support group is one way to obtain information and receive support from others. However, existing support groups are often attended by patients with significant disability, resulting in newly diagnosed patients being hesitant to return. Read More

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http://dx.doi.org/10.7224/1537-2073.2018-099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307875PMC
October 2019

The Spillover Effects of Supportive Neighboring Behavior on Mental Health and Career Satisfaction: A Longitudinal Research on Chinese Low-Income Employees.

Psychol Res Behav Manag 2020 15;13:507-515. Epub 2020 Jun 15.

Department of Construction Management, Kunming University of Science and Technology, Kunming, People's Republic of China.

Background: We examined the effects of supportive neighboring behavior on mental health and career satisfaction among Chinese low-income employees. We further examined the mediating roles of work interference with family (WIF) and of family interference with work (FIW) in this relationship.

Methods: A total of 220 Chinese low-income employees were selected via two-wave longitudinal survey in China; the time distance was five weeks. Read More

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http://dx.doi.org/10.2147/PRBM.S239435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304670PMC

Targeting Tumorigenicity of Breast Cancer Stem Cells Using SAHA/Wnt-b Catenin Antagonist Loaded Onto Protein Corona of Gold Nanoparticles.

Int J Nanomedicine 2020 11;15:4063-4078. Epub 2020 Jun 11.

Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

Background: Among various theories for the origin of cancer, the "stemness phenotype model" suggests a dynamic feature for tumor cells in which non-cancer stem cells (non-CSCs) can inter-convert to CSCs. Differentiation with histone-deacetylase inhibitor, vorinostat (SAHA), can induce stem cells to differentiate as well as enforces non-CSCs to reprogram to CSCs. To avoid this undesirable effect, one can block the Wnt-βcatenin pathway. Read More

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http://dx.doi.org/10.2147/IJN.S234636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295335PMC

Rapid antigen detection and molecular tests for group A streptococcal infections for acute sore throat: systematic reviews and economic evaluation.

Health Technol Assess 2020 Jun;24(31):1-232

Warwick Medical School, University of Warwick, Coventry, UK.

Background: Sore throat is a common condition caused by an infection of the airway. Most cases are of a viral nature; however, a number of these infections may be caused by the group A bacterium. Most viral and bacterial sore throat infections resolve spontaneously within a few weeks. Read More

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http://dx.doi.org/10.3310/hta24310DOI Listing

Tumor Volume Dynamics as an Early Biomarker for Patient-Specific Evolution of Resistance and Progression in Recurrent High-Grade Glioma.

J Clin Med 2020 Jun 27;9(7). Epub 2020 Jun 27.

Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.

Recurrent high-grade glioma (HGG) remains incurable with inevitable evolution of resistance and high inter-patient heterogeneity in time to progression (TTP). Here, we evaluate if early tumor volume response dynamics can calibrate a mathematical model to predict patient-specific resistance to develop opportunities for treatment adaptation for patients with a high risk of progression. A total of 95 T1-weighted contrast-enhanced (T1post) MRIs from 14 patients treated in a phase I clinical trial with hypo-fractionated stereotactic radiation (HFSRT; 6 Gy × 5) plus pembrolizumab (100 or 200 mg, every 3 weeks) and bevacizumab (10 mg/kg, every 2 weeks; NCT02313272) were delineated to derive longitudinal tumor volumes. Read More

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http://dx.doi.org/10.3390/jcm9072019DOI Listing

Online Education for Vaccination Competence Among Health Sciences Students.

Stud Health Technol Inform 2020 Jun;272:267-271

Department of Public and Community Health, Laboratory of Hygiene and Epidemiology, School of Public Health, University of West Attica, Athens, Greece.

The EDUVAC project aims to develop and implement a web-based course on educating vaccination competence among health sciences students. In the current study students' feedback and evaluation is assessed which guided the partners' efforts to improve the final course content and learning material that will be available for open access. After completing the web-based course, most of the students (N=103, 75. Read More

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http://dx.doi.org/10.3233/SHTI200546DOI Listing

Why choose geriatric medicine? A national survey among French postgraduate medical students.

Age Ageing 2020 Jun 27. Epub 2020 Jun 27.

CHU de Rennes, Rennes, France.

Since 2017, geriatric medicine has been available as a postgraduate specialty to French year 7 medical students. We investigated the incentives of the 171 French medical students who opted for geriatric medicine as a postgraduate specialty subsequent to year 6 national qualifying examinations in 2017. A prospective quantitative survey-based study was conducted by means of a questionnaire compiled online and sent by email between December 2017 and May 2018. Read More

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http://dx.doi.org/10.1093/ageing/afaa120DOI Listing

Are chief executive officers more likely to be first-borns?

PLoS One 2020 30;15(6):e0234987. Epub 2020 Jun 30.

Department of Finance and Business Economics, Foster School of Business, University of Washington, Seattle, Washington, United States of America.

We investigate the link between birth order and the career outcome of becoming Chief Executive Officer (CEO) of a company. CEOs are more likely to be the first-born, i.e. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0234987PLOS

The relationship between neurovascular coupling, vision and sensory performance, and concussion history in Special Operations Forces combat soldiers.

Clin Neuropsychol 2020 Jun 30:1-11. Epub 2020 Jun 30.

Matthew Gfeller Sport-Related Traumatic Brain Injury Research Center, Department of Exercise and Sport Science, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

To determine the relationship between neurovascular coupling (NVC), vision and sensory performance in Special Operations Forces (SOF) combat soldiers with and without concussion history. We studied 61 SOF combat soldiers (male, age = 33.8 ± 3. Read More

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http://dx.doi.org/10.1080/13854046.2020.1783367DOI Listing

Shift happens: the gender composition in clinical neuropsychology over five decades.

Clin Neuropsychol 2020 Jun 30:1-23. Epub 2020 Jun 30.

Psychology Department, Ohio University, Athens, Ohio, USA.

The current study utilizes five decades of data to demonstrate cohort differences in gender representation in governance, speaking at conferences, serving on editorial boards, and in scholarly productivity in clinical neuropsychology. Broadly examining gender disparities across domains of professional attainment helps illuminate the areas in which inequity in clinical neuropsychology is most pronounced and in need of ameliorative resources. Data from 1967 to 2017 were coded from publicly available information from the four major professional associations for clinical neuropsychology in the U. Read More

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http://dx.doi.org/10.1080/13854046.2020.1778791DOI Listing

Diversity and Inclusion in the Epidemiology Workforce, a Response to DeVilbiss et al.

Am J Epidemiol 2020 Jun 30. Epub 2020 Jun 30.

Boston University, Slone Epidemiology Center, Boston, MA.

Increasing participation by promoting diversity and inclusion in professional society membership has become an important topic for many scientific fields. In a recent issue of AJE, DeVilbiss et al reported results from a survey conducted by the SER Diversity and Inclusion Committee in which they measured several aspects of participation by sociodemographic and cultural variables among its members, Here, we summarize the major findings of their survey, put their results within the greater context of the epidemiology workforce, and provide suggestions on how the committee could expand its influence by considering measuring variables related to career outcomes and trajectories. This suggestion is based on an attempt to link the interventions being facilitated by SER, the participation indices it is trying to improve, and the greater mission of the SER to build sustainable career trajectories that produce the best science that will improve the health of human populations. Read More

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http://dx.doi.org/10.1093/aje/kwaa105DOI Listing

A Smorgasbord of Opportunities Exist to Improve Diversity, Inclusion, Representation, and Participation in Epidemiology: More Informed Action is Necessary Since Current Approaches are Insufficient.

Am J Epidemiol 2020 Jun 30. Epub 2020 Jun 30.

Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina; Intramural Program, National Institute on Minority Health and Health Disparities, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland.

The authors of the DeVilbiss et al. manuscript have taken on the noble and worthy cause to improve diversity, inclusion, representation, and participation across the Society for Epidemiologic Research (SER) membership - a reflection/microcosm of society. The objective of this commentary is to underscore the importance of diversity and to offer initiative ideas, which should be centered around inequity stemming from the widespread historical and contemporary maldistribution of power (e. Read More

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http://dx.doi.org/10.1093/aje/kwaa104DOI Listing

Improving Diversity and Promoting Inclusion in the Society for Epidemiologic Research Through Choice of Conference Location.

Am J Epidemiol 2020 Jun 30. Epub 2020 Jun 30.

National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina.

Scientific conferences provide attendees opportunities to network, share research, learn new skills and ideas, and initiate collaborations. Conference attendance is especially important for students and early career researchers who are establishing their research careers or looking for jobs. However, attending conferences can be expensive, and the high cost of conference attendance may hit students and early career researchers the hardest. Read More

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http://dx.doi.org/10.1093/aje/kwaa107DOI Listing

Experience adds up! The attitudes of medical students towards a career in general practice.

Educ Prim Care 2020 Jun 30. Epub 2020 Jun 30.

Medical Sciences Division, University of Oxford.

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http://dx.doi.org/10.1080/14739879.2020.1786729DOI Listing