Search Our Scientific Publications & Authors

Ann Thorac Surg 2019 Jan 11. Epub 2019 Jan 11.

Pediatr Crit Care Med 2019 Jan 11. Epub 2019 Jan 11.

Green Lane Paediatric and Congenital Cardiac Services, Starship Children's Hospital, Auckland, New Zealand.

Objectives: To raise awareness among pediatric intensive care specialists of catecholaminergic polymorphic ventricular tachycardia; an uncommon cause of polymorphic ventricular tachycardia and ventricular fibrillation arrest in children and young adults where epinephrine (adrenaline), even when given according to international protocols, can be counter-productive and life-threatening. We review three cases of cardiac arrest in children, later proven to be catecholaminergic polymorphic ventricular tachycardia related, where delay in recognition of this condition resulted in significantly longer resuscitation efforts, more interventions, and a longer time to return of spontaneous circulation.

Design: Retrospective case series. Read More

Resuscitation 2019 Jan 9. Epub 2019 Jan 9.

Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway; Department of Anaesthesia and Intensive Care Medicine, St.Olav Hospital, Trondheim, Norway.

During paediatric cardiopulmonary resuscitation (CPR), patients may transition between pulseless electrical activity (PEA), asystole, ventricular fibrillation/tachycardia (VF/VT), and return of spontaneous circulation (ROSC). The aim of this study was to quantify the dynamic characteristics of this process.

Methods: ECG recordings were collected in patients who received CPR at the Children's Hospital of Philadelphia (CHOP) between 2006 and 2013. Read More

Resuscitation 2019 Jan 9. Epub 2019 Jan 9.

Laboratory of Emergency Medical Services, Seoul National University Hospital Biomedical Research Institute, Seoul, Republic of Korea; Department of Emergency Medicine, Dongkuk University Ilsan Hospital, Republic of Korea. Electronic address:

Background: Dispatcher-assisted cardiopulmonary resuscitation (DA-CPR) programs are implemented to augment bystander CPR and improve outcomes of patients with out-of-hospital cardiac arrest (OHCA). To understand the pathway of how DA-CPR improves outcomes of OHCA, we aimed to evaluate the effect of DA-CPR on defibrillation and return of spontaneous circulation (ROSC) with survival to hospital discharge within 90 minutes.

Methods: We conducted a population-based observational study of all adults with OHCA with presumed cardiac aetiology treated by emergency medical services (EMS) between 2013 and 2016, using a national OHCA registry. Read More

Resuscitation 2019 Jan 9. Epub 2019 Jan 9.

Kyoto University Health Service, Yoshida-Honmachi, Sakyo-ku, Kyoto, 606-8501, Japan.

Background: Cardiopulmonary resuscitation (CPR) performed by bystanders is a key factor for out-of-hospital cardiac arrest (OHCA) survival. This study aimed to evaluate the relationship between CPR performed by off-duty medical professionals vs. laypersons and one-month survival with favorable neurological outcome after OHCA. Read More

J Pain Symptom Manage 2019 Jan 9. Epub 2019 Jan 9.

School of Nursing, Medical College, Chang Gung University, Department of Nursing, Chang Gung Memorial Hospital at Kaohsiung, and Division of Hematology-Oncology, Chang Gung Memorial Hospital at Linkou, 259 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan, Taiwan, 333, R.O.C. Electronic address:

Context/objective: Half of advanced cancer patients do not have accurate prognostic awareness (PA). However, few randomized clinical trials (RCTs) have focused on facilitating patients' PA to reduce their life-sustaining treatments (LSTs) at end of life (EOL). To address these issues, we conducted a double-blinded RCT on terminally ill cancer patients. Read More

J Cardiothorac Vasc Anesth 2018 Dec 5. Epub 2018 Dec 5.

Department of Anesthesiology and Resuscitation, Okayama University Hospital, Okayama, Japan.

Objective: Hyperchloremia recently has been shown to have an association with the development of acute kidney injury (AKI) in critically ill patients. However, there is little information about the prevalence of an abnormal chloride concentration after pediatric cardiac surgery and its association with postoperative AKI. The aim of this study was to determine the prevalence of hyperchloremia and its association with AKI in pediatric patients after cardiac surgery. Read More

Emergencias 2018 Dic;30(6):415-418

Unidad de Investigación en Emergencia y Desastre. Universidad de Oviedo, España.

En: On-site bystander use of automated external defibrillators (AEDs) was analized in Asturias, Spain, between January 2012 and December 2014. Hospital management and neurologic state on discharge were also studied. Our retrospective observational population-based design had 3 phases comrpising: 1) a telephone survey of facilities with onsite public-access AEDsc, 2) analysis of relevant case records held by the Asturian emergency medical service, and 3) analysis of relevant hospital case records. Read More

Can J Rural Med 2019 Jan-Mar;24(1):13-17

Golden and District Hospital, Golden, BC, Canada.

Introduction: The purpose of our study was to determine if regular cardiopulmonary resuscitation (CPR) practise improved the quality of nurses' chest compressions in a rural hospital.

Methods: The study was a prospective interventional trial measuring the effectiveness of brief, monthly CPR practice for rural nurses. The quality of nurses' chest compressions was measured before and after monthly practise with an interactive feedback device at the Golden and District Hospital, a rural facility in BC. Read More

Palliat Support Care 2019 Jan 14:1-6. Epub 2019 Jan 14.

New York Medical College,Department of Health Policy and Management,Valhalla, NY.

Objective: In the United States, approximately 20% patients die annually during a hospitalization with an intensive care unit (ICU) stay. Each year, critical care costs exceed $82 billion, accounting for 13% of all inpatient hospital costs. Treatment of sepsis is listed as the most expensive condition in US hospitals, costing more than $20 billion annually. Read More

Perfusion 2019 Jan 14:267659118823999. Epub 2019 Jan 14.

Department of Cardiovascular Surgery, Nagano Children's Hospital, Azumino, Japan.

Bidirectional Glenn procedure outcomes are very good; therefore, extracorporeal membrane oxygenation use as extracorporeal cardiopulmonary resuscitation is uncommon. We describe a 13-month-old female who required extracorporeal cardiopulmonary resuscitation for ventricular tachycardia provoked by transient myocarditis 6 months post-bidirectional Glenn procedure. After extracorporeal membrane oxygenation induction with cannulation on the cervical vessels, small skin incision was created on the subxiphoid area without sternotomy and the atrium was cannulated. Read More

Medicine (Baltimore) 2019 Jan;98(2):e14079

Department of Diagnostic Pathology.

Rationale: Pneumatosis intestinalis (PI) and hepatic portal venous gas (HPVG) are rare but potentially lethal conditions in which gas pathologically accumulates in the portal vein and intestinal wall, respectively. Proposed mechanisms include flatus escaping through an injured intestinal mucosa into the submucosa and thence into the portal venous system, or bacterial translocation (BT) of gas-forming enteric microorganisms from the gut into and through the intestinal wall to other organs. However, there has been no clear histopathological evidence to support these hypotheses. Read More

Eur Heart J Acute Cardiovasc Care 2019 Jan 11:2048872618823349. Epub 2019 Jan 11.

1 Department of Cardiology, Herlev and Gentofte Hospital, University of Copenhagen, Gentofte, Denmark.

Background:: Research regarding out-of-hospital cardiac arrest (OHCA) survival of diabetes patients is sparse and it remains unknown whether initiatives to increase OHCA survival benefit diabetes and non-diabetes patients equally. We therefore examined overall and temporal survival in diabetes and non-diabetes patients following OHCA.

Methods:: Adult presumed cardiac-caused OHCAs were identified from the Danish Cardiac Arrest Registry (2001-2014). Read More

Circ Cardiovasc Qual Outcomes 2019 Jan;12(1):e005444

Resuscitation 2019 Jan 7. Epub 2019 Jan 7.

Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada; Alberta Health Services, Calgary, Alberta, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Canada; Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada. Electronic address:

Objective: To compare mortality and neurodevelopmental outcomes of extremely low gestational age neonates who received delivery room extensive cardiopulmonary resuscitation (DR-CPR) to those who did not require DR-CPR.

Methods: Preterm neonates born at <29 weeks' gestational age between January 2010 and September 2011 and assessed at Canadian Neonatal Follow-Up Network centers were studied. Neonates who received DR-CPR were compared to those who did not require DR-CPR using univariate and multivariable analyses. Read More

Resuscitation 2019 Jan 7. Epub 2019 Jan 7.

Karolinska Institutet, Department of Medicine, Solna, Sweden; Center for Resuscitation Science, Stockholm, Sweden. Electronic address:

Background: Donation after brain death (DBD) is current praxis in Sweden. Circulatory death is far more common. Donation from patients suffering Out-of-Hospital Cardiac Arrest (OHCA) may have the potential to increase the organ-donor pool. Read More

Coron Artery Dis 2019 Jan 8. Epub 2019 Jan 8.

Department of Emergency Medicine and Chest Pain Center.

Background: There is no consensus on optimal antiplatelet and anticoagulation therapy after coronary stenting.

Methods: We identified randomized controlled trials (RCTs) published in PubMed, Cochrane Library, and Embase using the following keywords: 'antiplatelet', 'dual therapy', 'triple therapy', 'antithrombosis', 'indication for anticoagulation', 'percutaneous coronary intervention', and 'RCTs'. Primary safety end points were relative bleeding events, and secondary efficacy end points were major adverse cardiovascular events including stent thrombosis, death, myocardial infarction, and stroke. Read More

Circ Arrhythm Electrophysiol 2019 Jan;12(1):e006924

Center for Progress in Resuscitation (J.C., J.B., L.S., T.D.R., P.J.K., H.K.), University of Washington, Seattle.

Background: Quantitative measures of the ventricular fibrillation (VF) ECG waveform can assess myocardial physiology and predict cardiac arrest outcomes, making these measures a candidate to help guide resuscitation. Chest compressions are typically paused for waveform measure calculation because compressions cause ECG artifact. However, such pauses contradict resuscitation guideline recommendations to minimize cardiopulmonary resuscitation interruptions. Read More

Pediatr Emerg Care 2019 Jan 7. Epub 2019 Jan 7.

From the Divisions of Pediatric Surgery.

Aims: The aims of this study were to document the injury pattern in pediatric traumatic craniocervical dissociation (CCD) and identify features of survivors.

Methods: Pediatric traumatic CCDs, diagnosed between January 2004 and July 2016, were reviewed. Survivors and nonsurvivors were compared. Read More

Iran J Nurs Midwifery Res 2019 Jan-Feb;24(1):66-72

Department of Medical-Surgical Nursing, Hamadan University of Medical Sciences, Hamadan, Iran.

Background: Identifying the status of clinical education helps to improve the achievement of educational goals. This study aimed to compare the achievement of clinical skills in the final year nursing students.

Materials And Methods: In this descriptive analytical study, 157 nursing students in the seventh and eighth semesters were selected through a census method, who were compared with each other. Read More

Korean J Anesthesiol 2019 Jan 9. Epub 2019 Jan 9.

Department of Anesthesiology and Pain Medicine, Gangneung Asan Hospital, Gangneung, Korea.

In breast surgery, regional anesthesia has been mainly used for postoperative analgesia rather than primary anesthesia. Serratus anterior plane block is a new method for ultrasound-guided thoracic wall block, which is less invasive, and relative safe than conventional regional anesthetic techniques. We report a case of breast surgery under serratus anterior plane block with monitored anesthesia care in a 78-year-old patient with a medical history of cardiopulmonary resuscitation due to stress-induced cardiomyopathy caused by pneumonia. Read More

J Am Coll Cardiol 2019 Jan;73(1):70-88

Department of Medicine, Division of Cardiology, Duke University, Durham, North Carolina.

Sudden cardiac arrest (SCA) is one of the largest causes of mortality globally, with an out-of-hospital survival below 10% despite intense research. This document outlines challenges in addressing the epidemic of SCA, along the framework of respond, understand and predict, and prevent. Response could be improved by technology-assisted orchestration of community responder systems, access to automated external defibrillators, and innovations to match resuscitation resources to victims in place and time. Read More

Br J Nurs 2019 Jan;28(1):22-23

Graduate Tutor in Adult Nursing, Northumbria University.

Stuart Barker, Graduate Tutor in Adult Nursing, Northumbria University ( stuart.j.barker@northumbria. Read More

Pediatr Crit Care Med 2019 Jan;20(1):91-92

Department of Pediatrics, Akron Children's Hospital, Akron, OH.

Eur J Emerg Med 2019 Jan 5. Epub 2019 Jan 5.

Department of Emergency Medicine, University Hospital Ghent.

Objectives: Early recognition and appropriate bystander response has proven effect on the outcome of many critically ill patients, including those in cardiac arrest. We wanted to audit prehospital bystander response in our region and identify areas for improvement.

Patients And Methods: We prospectively collected data, including Emergency Medical Services dispatch center audio files, on all patients with a decreased level of consciousness presenting to the Ghent University Hospital prehospital emergency care unit (n=151). Read More

J Family Med Prim Care 2018 Nov-Dec;7(6):1493-1500

Department of Family and Community Medicine, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.

Background And Objective: Basic life support (BLS) and cardiopulmonary resuscitation (CPR) are urgently required and must be performed when cardiac arrest occurs. These lifesaving procedures must be learned by healthcare professionals. In developed countries, members of the public, academics, and students learn how to carry out these emergency procedures. Read More

Nan Fang Yi Ke Da Xue Xue Bao 2018 Dec;38(12):1514-1520

College of Forensic Medicine, Southern Medical University, Guangzhou 510515, China.

Objective: To analyze the morphological features and forensic pathological characteristics of cardiac ruptures of different causes for their differential diagnosis.

Methods: We analyzed the data of 44 autopsy cases of cardiac rupture from 2014 to 2017 in our institute, including 11 cases caused by blunt violence with intact pericardium, 4 caused by cardiopulmonary resuscitation (CPR), 9 by myocardial infarction, and 20 by aorta dissection rupture.The gross features and histopathological characteristics of cardiac rupture and pericardial effusion were analyzed and compared. Read More

Resuscitation 2018 Oct 26. Epub 2018 Oct 26.

Division of Intensive Care, Department of Anaesthesiology, Intensive Care and Pain Medicine, Helsinki University Hospital and University of Helsinki, Finland; Emergency Medicine and Services, Helsinki University Hospital and Department of Emergency Medicine, University of Helsinki, Finland. Electronic address:

Aim Of The Study: To evaluate in an established porcine post cardiac arrest model the effect of a mild hypercapnic ventilatory strategy on outcome.

Methods: The left anterior descending coronary artery was occluded in 14 pigs and ventricular fibrillation induced and left untreated for 12 min. Cardiopulmonary resuscitation was performed for 5 min prior to defibrillation. Read More

J Formos Med Assoc 2019 Jan 4. Epub 2019 Jan 4.

Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.

Background: Extracorporeal membrane oxygenation (ECMO) provides short-term cardiopulmonary support for patients with acute cardiac and respiratory failure. This study reported the survival rate for pediatric patients from Taiwan's national cohort.

Methods: Patients under the age of 18 who received ECMO from January 1, 2002 to December 31, 2012 were identified from the Taiwan National Health Insurance Research Database. Read More

J Am Heart Assoc 2019 Jan;8(1):e009436

5 Kyoto University Health Service Kyoto Japan.

Background Little is known about whether cardiopulmonary resuscitation ( CPR ) training can increase bystander CPR in the community or the appropriate target number of CPR trainings. Herein, we aimed to demonstrate community-wide aggressive dissemination of CPR training and evaluate temporal trends in bystander CPR . Methods and Results We provided CPR training (45-minute chest compression-only CPR plus automated external defibrillator use training or the conventional CPR training), targeting 16% of residents. Read More

Brain Stimul 2018 Dec 27. Epub 2018 Dec 27.

School of Biomedical Engineering and Imaging Medicine, Army Medical University, Chongqing, China. Electronic address:

Background: Transcranial direct current stimulation (tDCS) modulates neuronal activity and is a potential therapeutic tool for many neurological diseases. However, its beneficial effects on post cardiac arrest syndrome remains uncertain.

Objective/hypothesis: We investigated the effects of repetitive anodal tDCS on neurological outcome and survival in a ventricular fibrillation (VF) cardiac arrest rat model. Read More

Children (Basel) 2019 Jan 3;6(1). Epub 2019 Jan 3.

Centre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, Edmonton, AB T5H 3V9, Canada.

Annually, an estimated 13⁻26 million newborns need respiratory support and 2⁻3 million newborns need extensive resuscitation, defined as chest compression and 100% oxygen with or without epinephrine in the delivery room. Despite such care, there is a high incidence of mortality and neurologic morbidity. The poor prognosis associated with receiving chest compression alone or with medications in the delivery room raises questions as to whether improved cardiopulmonary resuscitation methods specifically tailored to the newborn could improve outcomes. Read More

Am J Perinatol 2019 Jan 4. Epub 2019 Jan 4.

Department of Obstetrics and Gynecology and Women's Health, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.

Objective:  To determine the effects of the Safe Motherhood Initiative's (SMI) obstetric hemorrhage bundle in New York State (NYS).

Methods:  In 2013, the SMI convened interprofessional workgroups on hemorrhage, venous thromboembolism, and hypertension tasked with developing evidence-based care bundles. Participating hospitals submitted data measured before, during, and after implementation of the hemorrhage bundle: maternal mortality, intensive care unit (ICU) admission, cardiovascular collapse, hysterectomy, and transfusion of ≥4 units of red blood cells (RBCs). Read More

South Med J 2019 Jan;112(1):60-65

Common in-flight emergencies include syncope, respiratory symptoms, nausea/vomiting, cardiac symptoms, and seizures. Flight conditions, such as changes in air pressure and humidity, can exacerbate existing chronic medical conditions. In 2017, US airlines carried 849. Read More

J Nurses Prof Dev 2019 Jan/Feb;35(1):6-11

Bette Mariani, PhD, RN, ANEF, is Associate Professor, Villanova University M. Louise Fitzpatrick College of Nursing, Villanova, Pennsylvania. Kelly Ann Zazyczny, MSN, RN, CPN, is System Nurse Manager, Pediatrics and Vascular Access, Main Line Health System, Bryn Mawr Hospital, Bryn Mawr, Pennsylvania. Patricia Decina, MHA, BSN, RN, CPN, is Staff Nurse 5, Main Line Health System, Bryn Mawr Hospital, Bryn Mawr, Pennsylvania. Lisa Waraksa, BSN, RN, CPN, is Staff Nurse 4, Main Line Health System, Bryn Mawr Hospital, Bryn Mawr, Pennsylvania. Patricia Snyder, BSN, RN, CPA, is Clinical Coordinator, Main Line Health System, Bryn Mawr Hospital, Bryn Mawr, Pennsylvania. Elizabeth Gallagher, MSN, RN, CPN, is Staff Nurse 5, Main Line Health System, Bryn Mawr Hospital, Bryn Mawr, Pennsylvania. Carol Hand, MHA, BSN, RNC-NIC, is Clinical Nurse Educator, Neonatal Intensive Care unit, Main Line Health System, Bryn Mawr Hospital, Bryn Mawr, Pennsylvania.

Positive outcomes for pediatric in-hospital cardiopulmonary arrest remain low with little change in mortality rates. Infrequently used clinical knowledge and skills decline quickly, contributing to poor quality of resuscitation. The aim of this pilot study exploring the outcomes of repeated pediatric mock code simulations with structured debriefing demonstrated statistically significant differences in participants' knowledge of pediatric emergencies, with no significant decline in resuscitation skills. Read More

J Am Heart Assoc 2018 Nov;7(21):e010283

1 Department of Emergency Medicine Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.

Background After cardiopulmonary resuscitation, the protective effects of therapeutic hypothermia induced by conventional cooling are limited. Recently, esophageal cooling ( EC ) has been shown to be an effective, easily performed approach to induce therapeutic hypothermia. In this study we investigated the efficacy of EC and its effects on early markers of postresuscitation cardiac and neurological injury in a porcine model of cardiac arrest. Read More

Circ J 2018 Dec 29. Epub 2018 Dec 29.

Emergency Medical Center, Kagawa University Hospital.

Background: The aim of the present study was to determine whether instructors could accurately assess chest compression quality visually, considering the association between chest compression depth and rate. Methods and Results: In this prospective, observational study, the quality of chest compressions performed by a simulated actor in a video was visually assessed by certified instructors. The film consisted of 14 case scenarios, each including a combination of depth (2 patterns: adequate, 5-6 cm; and inadequate, <5 cm) and rate (7 categories: compressions 90-150 times/min in increments of 10 times/min). Read More

Prehosp Disaster Med 2019 Jan 3:1-8. Epub 2019 Jan 3.

1Institute of Health and Biomedical Innovation,Queensland University of Technology,Brisbane,Australia.

Background: In addition to the traditional logistics role, pharmacists are undertaking important new roles in disasters. Despite this, little is known about the level of acceptance of these activities by other providers.ProblemThe aim of this study was to determine the international opinion of disaster and health professionals regarding the emerging roles of pharmacists in disasters. Read More

Int J Public Health 2019 Jan 3. Epub 2019 Jan 3.

Collaboration for Evidence, Research and Impact in Public Health, School of Public Health, Faculty of Health Sciences, Curtin University, GPO Box U1987, Perth, WA, 6845, Australia.

Objectives: Drowning is a public health challenge. Children of migrants may be at increased risk as parents may be unaware of local water safety issues. This study explores differences between Australian-born and migrant parents in Western Australia for: (1) swimming ability; (2) supervision; (3) water familiarisation; and (4) cardiopulmonary resuscitation (CPR) training. Read More

PLoS One 2019 2;14(1):e0208113. Epub 2019 Jan 2.

Institute for Emergency Medicine and Department of Anaesthesiology and Intensive Care Medicine, Schleswig-Holstein University Hospital, Campus Kiel, Kiel, Germany.

Background: Cardiac arrest is an event with a limited prognosis which has not substantially changed since the first description of cardiopulmonary resuscitation (CPR) in 1960. A promising new treatment approach may be mechanical CPR devices (mechanical CPR).

Methods: In a retrospective analysis of the German Resuscitation Registry between 2007-2014, we examined the outcome after using mechanical CPR on return of spontaneous circulation (ROSC) in adults with out-of-hospital cardiac arrest (OHCA). Read More

Pediatr Emerg Care 2018 Dec 27. Epub 2018 Dec 27.

Division of Pediatric Emergency Medicine, Morgan Stanley Children's Hospital of New York, Columbia University Medical Center, New York, NY.

Background: Capnography and cardiopulmonary resuscitation (CPR) feedback devices have been shown to improve resuscitation outcomes, with the American Heart Association recommending their use during advanced life support (ALS). Little is known about the availability of these devices, their protocoled use, and the attitudes toward them in the prehospital setting.

Objectives: The objectives of this study were to assess the availability of capnography and CPR feedback devices among prehospital ALS agencies in New York State (NYS), to describe the protocoled use of these devices, and to evaluate the attitudes of providers toward the use of these devices. Read More

Resuscitation 2018 Dec 29. Epub 2018 Dec 29.

Department of Emergency Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, 20, Boramae-ro 5-gil, Dongjak-gu, Seoul 07061, Republic of Korea.

Purpose: We investigated the change in pupil size and pupil light reflex (PLR) using a pupillography capable of continuous measurement both during CPR and immediately following the return-of-spontaneous circulation (ROSC) in out-of-hospital cardiac arrest (OHCA) comatose patients in an emergency department.

Methods: Pupil size and PLR were continuously measured both during CPR and immediately following ROSC until intensive care unit (ICU) admission. The changes in pupil sizes during CPR were categorized into three groups (no change - N, decreased - D, and increased - I groups). Read More

Resuscitation 2018 Dec 28. Epub 2018 Dec 28.

Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.

Resuscitation 2018 Dec 28. Epub 2018 Dec 28.

Departments of Emergency Medicine and Pediatrics, Penn State Hershey Medical Center, 500 University Drive, Hershey, PA, 17033, USA. Electronic address:

Resuscitation 2018 Dec 26;134:10-18. Epub 2018 Dec 26.

Department of Community Emergency Health and Paramedic Practice, Monash University, Frankston, Victoria, Australia; Department of Epidemiology and Preventive Medicine, Monash University, Prahran, Victoria, Australia; Centre for Research and Evaluation, Ambulance Victoria, Doncaster, Victoria, Australia; Discipline of Emergency Medicine, University of Western Australia, Crawley, Western Australia, Australia.

Background: Out-of-hospital cardiac arrests (OHCA) precipitated by drug overdose (OD) are becoming an increasing public health problem in developed countries. Empirical data on the global incidence and outcomes are needed to guide preventive and treatment strategies.

Methods: We conducted a systematic review using MEDLINE, Embase, Emcare, All EBM Reviews and CINAHL to identify observational or interventional studies reporting the incidence or outcomes of adult OHCA precipitated by drug OD between 1990 and 2018. Read More

Medicine (Baltimore) 2018 Dec;97(52):e13819

The study was aimed to identify the training received in Emergency Medicine by physicians and the limitations and difficulties self-perceived by those physicians to assist in emergencies, as well as to analyze the differences according to the work context.Observational cross-sectional study made by a survey using a self-administered questionnaire to a representative simple random sample (with replacement) of 294 doctors (n) working at the Primary Health Care centers out of the total of 851 doctors (N) that form the staff of physicians of Primary Health Care system of Asturias (Spain).In rural areas, the most frequently mentioned reasons were the lack of practical skills (32. Read More

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2018 Dec;30(12):1178-1183

Department of Intensive Care Medicine, the First Affiliated Hospital of Xiamen University, Xiamen 361003, Fujian, China. Corresponding author: Zhang Minwei, Email:

Objective: To investigate the effect of exogenous hydrogen sulfide (HS) on intestinal mucosal barrier after cardiopulmonary resuscitation (CPR) in cardiac arrest (CA) rabbits.

Methods: Forty-four male New Zealand rabbits were divided into sham operation group (Sham group, n = 12), post-cardiac arrest syndrome (PCAS) group (n = 16) and H2S intervention group (PCAS+NaHS, n = 16) according to random number table method. The rabbit model of PCAS was established by tracheal clamping and suffocation, and CPR was started at 5 minutes after CA. Read More

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2018 Dec;30(12):1150-1153

Centre of PICU, Children's Hospital of Nanjing Medical University, Nanjing 210008, Jiangsu, China. Corresponding author: Miao Hongjun, Email:

Objective: To explore the clinical application value of the continuous blood purification (CBP) technology in pediatric intensive care unit (ICU).

Methods: A retrospective study was conducted. All CBP patients admitted to pediatric ICU of Children's Hospital of Nanjing Medical University from 2015 to 2017 were enrolled. Read More

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2018 Dec;30(12):1117-1118

Emergency Center of the Third Medical Center of Chinese PLA General Hospital, Beijing 100039, China (Wang LX); Department of Emergency, Xinqiao Hospital, Military Medical University, Chongqing 400037, China (Shi Z); Department of Emergency, Army Medical Center of PLA, Chongqing 400042, China (Qu JF). Corresponding author: Wang Lixiang, Email:

Objective: China's cardiopulmonary resuscitation (CPR) training in the form of a Chinese tutor classes for the training of CPR has spread across the country. It is supported by three Chinese original theoretical systems: "2016 Chinese cardiopulmonary resuscitation expert consensus", "2018 China cardiopulmonary resuscitation training expert consensus", and "Chinese public health guidelines for cardiopulmonary resuscitation". There are five characteristics in the classes, such as the "three analysis" "three-prevention" (precaution, prewarning and early identification), "three-ways" (standardization, diversification and individuation), "three lives" (demutation, transcending and extension), "three dimensional" (time, space and society). Read More

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2018 Dec;30(12):1107-1116

Emergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China (Mi YH); Emergency Center of the Third Medical Center of Chinese PLA General Hospital, Beijing 100039, China (Wang LX); Fuwai Hospital Chinese Academy of Medical Sciences, Beijing 100037, China (Cheng XS). Corresponding author: Wang Lixiang, Email: