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    3127 results match your criteria Cardiomyopathy Takotsubo

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    Recurrence of Postoperative Stress-Induced Cardiomyopathy Resulting from Status Epilepticus.
    Case Rep Crit Care 2017 22;2017:8063837. Epub 2017 Jan 22.
    Department of Critical Care Medicine, Naval Medical Center Portsmouth, Portsmouth, VA, USA.
    Introduction. Classically, stress-induced cardiomyopathy (SIC), also known as takotsubo cardiomyopathy, displays the pathognomonic feature of reversible left ventricular apical ballooning without coronary artery stenosis following stressful event(s). Temporary reduction in ejection fraction (EF) resolves spontaneously. Read More

    Takotsubo Syndrome After Cardiopulmonary Resuscitation During Emergency Cesarean Delivery.
    Obstet Gynecol 2017 Mar;129(3):521-524
    Departments of Obstetrics and Gynecology and Cardiology, Klinikum Kempten Oberallgäu, Kempten, Germany.
    Background: Takotsubo syndrome is a rare, stress-related, and reversible form of acute heart failure primarily affecting postmenopausal women. It is characterized by left ventricular dysfunction with a classic apical and midventricular wall motion abnormality (apical ballooning).

    Case: A 28-year-old woman, gravida 2 para 1, at 30 4/7 weeks of gestation was admitted with fetal bradycardia, a fully dilated cervix, and breech presentation. Read More

    Transient left atrial dysfunction is a feature of Takotsubo syndrome.
    J Cardiovasc Magn Reson 2017 Feb 6;19(1):15. Epub 2017 Feb 6.
    University Heart Center Lübeck, Medical Clinic II (Cardiology/Angiology/Intensive Care Medicine), University Hospital Schleswig-Holstein, Ratzeburger Allee 160, 23538, Lübeck, Germany.
    Background: Takotsubo syndrome (TTS) is characterized by a transient left and/or right ventricular dysfunction as a consequence of a distinctive pattern of regional wall motion abnormalities. However, a systematic evaluation of the left atrial (LA) function in patients with TTS is lacking. The aim of the present study was therefore to comprehensively assess LA performance indexes and function in patients with TTS. Read More

    ST-segment Elevation: Myocardial Infarction or Simulacrum?
    Rev Cardiovasc Med 2016 ;17(3-4):85-99
    Aurora Cardiovascular Services, St. Luke's Medical Center, University of Wisconsin School of Medicine and Public Health, Milwaukee, WI.
    A rapid diagnosis of ST-segment elevation myocardial infarction (STEMI) is mandatory for optimal treatment of an acute coronary syndrome. However, a small number of patients with suspected STEMI are afflicted with other medical conditions. These medical conditions are rare, but important clinical entities that should be considered when evaluating a STEMI alert. Read More

    [Takotsubo cardiomyopathy: incidence, etiology, complications, therapy and prognosis].
    Vnitr Lek 2016 ;62(12):1021-1027
    Takotsubo syndrome is presented by acute heart failure and looks like acute coronary syndrome and truly mimics its clinical and ECG features. It is characterised by transient contractility disorder of mostly apical part of left ventricle without any presence of occlusive coronary disease. It is found in 1-2 % patients admitted to the hospital care for acute coronary syndrome. Read More

    Delayed normalization of electrocardiograms in patients with takotsubo cardiomyopathy due to aneurysmal subarachnoid hemorrhage.
    World Neurosurg 2017 Jan 27. Epub 2017 Jan 27.
    Department of Cardiology, Miyazaki Medical Association Hospital, 738-1 Funato, Shinbeppu-cho, Miyazaki, Miyazaki 880-0834, Japan.
    Background: Takotsubo cardiomyopathy (TCM) is caused by excessive physical and mental stress, and sometimes causes potentially fatal arrhythmias such as torsades de pointes. This study characterized the features of TCM due to aneurysmal subarachnoid hemorrhage (SAH), particularly the delayed normalization of electrocardiograms compared to that of transthoracic echocardiograms.

    Methods: Ten patients with TCM were selected from the 450 SAH patients treated in our hospital between January 2007 and November 2015. Read More

    [Takotsubo cardiomyopathy recurrence in patient with chronic kidney disease: case report and literature review].
    G Ital Nefrol 2016 Nov-Dec;33(6)
    Takotsubo cardiomyopathy (CT) is a syndrome characterized by an acute and transient left ventricular dysfunction, electrocardiographic abnormalities suggestive of acute coronary syndrome, chest pain and/or dyspnea, left ventricular mid-apical segments akinesia and normal coronary angiography. It is mainly observed in postmenopausal women after an intense physical or mental stress. The course is usually favourable but sometimes severe complications occur. Read More

    Clinical and echocardiographic analysis of patients suffering from recurrent takotsubo cardiomyopathy.
    J Geriatr Cardiol 2016 Nov;13(11):888-893
    First Department of Medicine, Faculty of Medicine, University Medical Centre Mannheim (UMM), University of Heidelberg, Mannheim, Germany; DZHK (German Center for Cardiovascular Research), Partner Site, Heidelberg-Mannheim, Mannheim, Germany.
    Background: Recurrence of takotsubo cardiomyopathy (TTC) is a well-known complication. However, current literature lists only a few isolated cases. We aimed to determine the incidence and clinical significance of recurrent TTC. Read More

    Recurrent takotsubo with prolonged QT and torsade de pointes and left ventricular thrombus.
    J Saudi Heart Assoc 2017 Jan 6;29(1):44-52. Epub 2016 Aug 6.
    Department of Cardiovascular Disease, International Medical Center, Jeddah, Saudi Arabia.
    Takotsubo cardiomyopathy, also known as "takotsubo syndrome," refers to transient apical ballooning syndrome, stress cardiomyopathy, or broken heart syndrome and is a recently recognized syndrome typically characterized by transient and reversible left ventricular dysfunction that develops in the setting of acute severe emotional or physical stress. Increased catecholamine levels have been proposed to play a central role in the pathogenesis of the disease, although the specific pathophysiology of this condition remains to be fully determined. At present, there have been very few reports of recurrent takotsubo cardiomyopathy. Read More

    Genome-wide association study in takotsubo syndrome - Preliminary results and future directions.
    Int J Cardiol 2017 Jan 15. Epub 2017 Jan 15.
    University Heart Center of Lübeck, Medical Clinic II, Department of Cardiology, Angiology, Intensive Care Medicine, Lübeck, Germany; German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany; Institute for Integrative and Experimental Genomics, University of Lübeck, Lübeck, Germany.
    Background: Takotsubo syndrome (TS) is an acute non-ischemic cardiomyopathy characterized by transient regional systolic dysfunction of the left and/or right ventricle with still unknown etiology. The aim of the current study was to conduct for the first time a genome-wide association study (GWAS) in a cohort of TS patients to identify potential genetic risk variants.

    Methods: This single-center study was conducted at the University Heart Center Lübeck from 2008 to 2016. Read More

    Pheochromocytoma Multisystem Crisis Behaving Like Interstitial Pneumonia: An Autopsy Case.
    Intern Med 2017 15;56(2):149-152. Epub 2017 Jan 15.
    Department of Cardiology, Fuchu Hospital, Japan.
    Pheochromocytoma multisystem crisis is a rare and life-threatening disease that is associated with numerous symptoms and which is also difficult to diagnose. We herein report an autopsy case of a 61-year-old man who died due to pheochromocytoma multisystem crisis. The patient complained of vomiting and breathlessness. Read More

    Autonomic function in Takotsubo syndrome long after the acute phase.
    Int J Cardiol 2017 Mar 4;231:222-224. Epub 2017 Jan 4.
    Department of Clinical and Experimental Medicine, University of Parma, Italy.
    Objectives: Although it is well documented that an exaggerated sympathetic stimulation plays a role in the development of Takotsubo Syndrome (TS) during the acute phase, only few studies have focused on autonomic adaptations in stress-induced cardiomyopathy long after the acute phase. Aim of the study was to investigate whether an impairment of the autonomic function is still present long after a TS event. This was done by comparing the response to a maximal exercise test in TS patients after apparent recovery (>1-year after the acute event) with that obtained in healthy subjects and in post-myocardial infarction (post-MI) patients. Read More

    Clinical features and three-year outcomes of Takotsubo (stress) cardiomyopathy: Observational data from one center.
    Hellenic J Cardiol 2016 Nov 16. Epub 2016 Nov 16.
    Department of Radiology, Nuclear Medicine and Medical Physics, Vilnius University, Lithuania.
    Objective: The natural history, management, and outcome of Takotsubo (stress) cardiomyopathy (TTC) is not clear. The aim of this study was to investigate clinical features, define prognostic predictors, and assess the clinical course and outcomes of patients with TTC.

    Methods: We analyzed 64 patients (52 women) meeting the proposed Mayo Clinic diagnostic criteria for TTC. Read More

    Acute pulmonary edema caused by takotsubo cardiomyopathy in a pregnant woman undergoing transvaginal cervical cerclage: A case report.
    Medicine (Baltimore) 2017 Jan;96(1):e5536
    Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
    Background: The physiological changes associated with pregnancy may predispose pregnant women to pulmonary edema. Other known causes of pulmonary edema during pregnancy include tocolytic drugs, preeclampsia, eclampsia, and peripartum cardiomyopathy.

    Methods: We describe a rare case of pulmonary edema caused by takotsubo cardiomyopathy in a pregnant woman at 14 weeks of gestation who was undergoing emergency transvaginal cervical cerclage. Read More

    Left ventricular function after takotsubo is not fully recovered in long-term follow-up: A speckle tracking echocardiography study.
    Cardiol J 2017 Jan 10. Epub 2017 Jan 10.
    Klinika Kardiochirurgii i Chirurgii Naczyniowej Uniwersyteckie Centrum Kliniczne ul. Dębinki 7, 80-211 Gdańsk.
    Background: Complete improvement of left ventricle (LV) systolic function is an essential feature of takotsubo cardiomyopathy (TTC). It is suggested that 2-dimensional speckle tracking echocardiography (2D STE) can evaluate LV dysfunction more accurately than conventional echocardiography. Thus, the purpose of this research was to assertain whether LV function recovery is complete after the acute phase of TTC using 2D STE commencing 6 months after discharge. Read More

    Application of Cardiac Troponin in Cardiovascular Diseases Other Than Acute Coronary Syndrome.
    Clin Chem 2017 Jan 10;63(1):223-235. Epub 2016 Oct 10.
    Department of Medical Sciences and.
    Background: Increased cardiac troponin concentrations in acute coronary syndrome (ACS) identify patients with ongoing cardiomyocyte necrosis who are at increased risk. However, with the use of more precise assays, cardiac troponin increases are commonly noted in other cardiovascular conditions as well. This has generated interest in the use of cardiac troponin for prognostic assessment and clinical management of these patients. Read More

    Cardiogenic Shock due to Psychosis-Induced Inverted Takotsubo Cardiomyopathy Bridged-to-Recovery with a Percutaneous Left Ventricular Assist Device.
    Case Rep Cardiol 2016 12;2016:5498650. Epub 2016 Dec 12.
    Department of Cardiovascular Sciences, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
    Inverted Takotsubo cardiomyopathy, a less common variant in the spectrum of stress-induced cardiomyopathy, is increasingly being reported. This report describes an acute psychiatric illness leading to the onset of this syndrome. The patient presented here developed cardiogenic shock but successfully recovered with the use of a percutaneous left ventricular assist device. Read More

    Takotsubo cardiomyopathy: a known unknown foe of asthma.
    J Asthma 2017 Jan 5. Epub 2017 Jan 5.
    a Department of Respiratory Medicine , University Hospital of Larissa, Faculty of Medicine, University of Thessaly, BIOPOLIS , 41500 , Larissa , Greece.
    Introduction: Patients with uncontrolled asthma are at a greater risk of asthma attacks requiring emergency room visits or hospital admissions. Takotsubo cardiomyopathy is potentially a significant complication in a course of status asthmaticus.

    Case Study: We present a 43-year-old female patient who presented with status asthmaticus further complicated with takotsubo cardiomyopathy. Read More

    Takotsubo cardiomyopathy: FDG myocardial uptake pattern in fasting patients. Comparison of PET/CT, SPECT, and ECHO results.
    J Nucl Cardiol 2017 Jan 4. Epub 2017 Jan 4.
    Nuclear Medicine Department, Medical University of Warsaw, Banacha 1a, 02-097, Warsaw, Poland.
    Background: The aim of this study was to assess the accumulation pattern of 18F-FDG in fasting patients with takotsubo cardiomyopathy (TTC) and to correlate the results with perfusion scintigraphy and echocardiography.

    Methods: 18 consecutive patients with TTC were identified by clinical symptoms, cardiac catheterization, and echocardiography. Coronary angiography (CA) and transthoracic echocardiography (TTE) were performed on the day of the onset of symptoms. Read More

    Takotsubo cardiomyopathy associated with Miller-Fisher syndrome.
    Am J Emerg Med 2016 Dec 22. Epub 2016 Dec 22.
    Department of Cardiology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA. Electronic address:
    51-year-old female who presented with progressive paresthesia, numbness of the lower extremities, double vision, and trouble walking. Physical exam was remarkable for areflexia, and ptosis. Her initial EKG showed nonspecific ST segment changes and her Troponin T was elevated to 0. Read More

    Combined therapy with beta-blockers and ACE-inhibitors/angiotensin receptor blockers and recurrence of Takotsubo (stress) cardiomyopathy: A meta-regression study.
    Int J Cardiol 2017 Mar 23;230:281-283. Epub 2016 Dec 23.
    Icahn School of Medicine at Mount Sinai, New York, NY, United States; Division of Cardiology, Elmhurst Hospital Center, Elmhurst, NY, United States.

    Myocardial strain may be useful in differentiating Takotsubo cardiomyopathy from left anterior descending coronary artery ischemia.
    Int J Cardiol 2017 Mar 21;230:359-363. Epub 2016 Dec 21.
    Department of Medicine, Section of Cardiology, University of Chicago, Chicago, IL, USA. Electronic address:
    Background: Stress-induced cardiomyopathy (SCM) is characterized by transient apical wall motion abnormalities of the left ventricle (LV) in the absence of obstructive coronary artery disease. Although the echocardiographic findings of SCM mimic those of left anterior descending coronary artery ischemia or infarction (LAD), the regional LV wall motion pattern and degree of RV involvement may differ.

    Methods: We sought to systematically assess regional LV and RV function with myocardial strain imaging to assess if ventricular involvement may differ between SCM and LAD. Read More

    Takotsubo Cardiomyopathy Associated with Primary Hyperthyroidism Secondary to Toxic Multinodular Goiter.
    Int J Angiol 2016 Dec 23;25(5):e121-e122. Epub 2015 Mar 23.
    Department of Endocrinology, Gold Coast University Hospital, Gold Coast, Australia; School of Medicine, Griffith University, Gold Coast, Australia.
    Takotsubo cardiomyopathy is increasingly recognized as a distinct clinical entity. An association with thyroid disease has been identified in several case reports, mostly in the context of Grave disease. We report the case of a 67-year-old woman presenting with takotsubo cardiomyopathy and thyrotoxicosis secondary to toxic multinodular goiter. Read More

    Respiratory and Cardiac Characteristics of ICU Patients Aged 90 Years and Older: A Report of 12 Cases.
    Chin Med Sci J 2016 Mar;31(1):37-42
    Department of Critical Care Medicine, Cancer Hospital and Institute, Chinese Academy of Medical Sciences & Peking Union Medical College, 100021 Beijing, China.
    Objective To investigate the respiratory and cardiac characteristics of elderly Intensive Care Unit (ICU) patients.Methods Twelve senior ICU patients aged 90 years and older were enrolled in this study. We retrospectively collected all patients' clinical data through medical record review. Read More

    Isolated right ventricular takotsubo cardiomyopathy: a case report and literature review.
    Pol Merkur Lekarski 2016 Dec;41(246):283-286
    Department of Internal Medicine, Józef Struś Hospital, Poznań, Poland.
    : In about one quarter of patients with stress-induced takotsubo cardiomyopathy (TC) concomitant involvement of right ventricle (RV) can be observed. Opposite to this biventricular form of TC, isolated right ventricular takotsubo cardiomyopathy (RVTC) was described only in a few cases and so far has not been listed as a specific type of TC. The authors present a case of a 87-year-old demented female admitted with pneumonia in whom echocardiography revealed RV apical ballooning while the left ventricle function was quite normal. Read More

    Post-partum hemorrhage complicated by reverse-Takotsubo cardiogenic shock; a novel therapeutic approach.
    Am J Emerg Med 2016 Dec 19. Epub 2016 Dec 19.
    Department of Critical Care, University Hospital of Larissa, School of Medicine, University of Thessaly, Larissa, Thessaly, Greece. Electronic address:
    Takotsubo Cardiomyopathy (TTC) is a type of transient, yet severe left ventricular systolic dysfunction, rarely complicating extreme emotional stress ("primary" TTC) or critical medical/surgical illness ("secondary" TTC forms). Although usually reversible, TTC may result in cardiogenic shock with dismal prognosis. "Secondary" TTC forms are particularly in danger for this complication, bearing significantly worse short and long-term prognosis. Read More

    Optical Coherence Tomography to Evaluate Plaque Burden and Morphology in Patients With Takotsubo Syndrome.
    J Am Heart Assoc 2016 Dec 22;5(12). Epub 2016 Dec 22.
    Medical Clinic II (Cardiology/Angiology/Intensive Care Medicine), University Heart Center Lübeck University Hospital Schleswig-Holstein, Lübeck, Germany.
    Background: Disrupted atherosclerotic plaques in the left anterior descending coronary artery are discussed controversially as a potential pathophysiological mechanism in Takotsubo syndrome (TTS). Therefore, the aim of the present study was to assess plaque burden and morphology by using optical coherence tomography in patients with TTS.

    Methods And Results: A total of 23 consecutive TTS patients were included in this single-center study and underwent optical coherence tomography imaging of the left main coronary artery and the left anterior descending coronary artery at acute presentation. Read More

    The ECG in the differential diagnosis between takotsubo cardiomyopathy and acute coronary syndrome.
    Expert Rev Cardiovasc Ther 2017 Feb 29;15(2):137-144. Epub 2016 Dec 29.
    a Cardiology and Arrhythmology Clinic , Marche Polytechnic University, University Hospital 'Ospedali Riuniti,' , Ancona , Italy.
    Introduction: Takotsubo cardiomyopathy (TC) is an acquired cardiomyopathy affecting mostly postmenopausal women mimicking an acute coronary syndrome (ACS). TC clinical presentation involves chest pain, elevated cardiac enzymes, wall motion abnormalities and electrocardiographic changes, all of which share striking similarities to ACS. Areas covered: Differential diagnosis between TC and ACS can be complex since there are no reliable and widely-accepted electrocardiographic criteria and, at the moment, only coronary angiography can rule out one of the two diagnoses with good certainty. Read More

    Supra-Hisian Conduction Block as an Unusual Presenting Feature of Takotsubo Cardiomyopathy.
    Pacing Clin Electrophysiol 2016 Dec 21. Epub 2016 Dec 21.
    Department of Cardiology, Amrita Institute of Medical Sciences, Ponekkara, Kochi, Kerala, India.
    Background: Atrioventricular (AV) block is rare in Takotsubo cardiomyopathy (TC).

    Case Report: A 66-year-old female presented with fatigue. Her electrocardiogram revealed 3:2 Mobitz Type II AV block, confirmed to be supra-Hisian by electrophysiological study. Read More

    Takotsubo Cardiomyopathy in Traumatic Brain Injury.
    Neurocrit Care 2016 Dec 20. Epub 2016 Dec 20.
    Department of Neurology, Neurological Intensive Care Unit, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
    Background: Takotsubo cardiomyopathy (TC) is a well-known complication after aneurysmal subarachnoid hemorrhage and has been rarely described in patients with traumatic brain injury (TBI).

    Methods: Case report and review of literature.

    Results: Here, we report a 73-year-old woman with mild traumatic brain injury (TBI) presenting in cardiogenic shock. Read More

    Takotsubo Cardiomyopathy presenting as ST-elevation myocardial infarction: wide triggering spectrum and specific echocardiographical pattern in a consecutive case series report.
    Med Ultrason 2016 Dec;18(4):475-480
    1st Medical Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, Interventional Cardiology Department, Emergency County Hospital, Cluj-Napoca, Romania.
    We report a series of six consecutive cases of Takotsubo Cardiomyopathy (TCM) presenting as ST-elevation acute myocardial infarction and consequently addressed to the emergency coronary angiography, inside a time-frame of one year (2015). This series underlines the wide possible triggering spectrum and clinical severity of TCM and recognizes echocardiography as an essential imaging technique in the diagnosis due to its widespread availability and feasibility in the acute care setting. Read More

    A Case Report of Reversible Takotsubo Cardiomyopathy after Amphetamine/Dextroamphetamine Ingestion in a 15-Year-Old Adolescent Girl.
    J Pediatr 2016 Dec 13. Epub 2016 Dec 13.
    Harvard Medical Toxicology Program, Boston Children's Hospital, Boston, MA; Department of Medicine, Division of Emergency Medicine, Boston Children's Hospital, Boston, MA.
    Stimulant medications are used in the treatment of attention deficit hyperactivity disorder and serious cardiac complications can occur when these medications are abused. We present a 15-year-old adolescent girl who was found to have a Takotsubo cardiomyopathy after acute amphetamine/dextroamphetamine ingestion. Read More

    Takotsubo cardiomyopathy after cesarean section: A case report and literature review.
    J Obstet Gynaecol Res 2017 Feb 9;43(2):392-396. Epub 2016 Dec 9.
    Department of Obstetrics, Aragon Institute for Health Research (IIS Aragón), Zaragoza, Spain.
    Takotsubo cardiomyopathy (TCM) is clinically identical to acute myocardial infarction. We report an unusual case of TCM and review similar cases in pregnant women. A young woman with no pre-existing cardiovascular risk factors suffered sudden dyspnea during a cesarean section. Read More

    A Heartbreaking Renal Transplantation: Is Norepinephrine the Culprit to Blame?
    Transplant Proc 2016 Nov;48(9):3088-3091
    Transplantation Unit, Athens University School of Medicine, "Laiko" General Hospital, Athens, Greece.
    Introduction: Takotsubo cardiomyopathy (TCM), also known as "broken heart syndrome," "apical ballooning syndrome," and "stress-induced cardiomyopathy," was first described in Japanese patients in 1990 by Sato et al. TCM is an increasingly recognized syndrome characterized by transient and reversible systolic dysfunction of the apical and middle segments of the left ventricle. This syndrome resembles acute myocardial infarction in the absence of evident coronary artery occlusion. Read More

    Predictive Value of QRS Duration at Admission for In-Hospital Clinical Outcome of Takotsubo Cardiomyopathy.
    Circ J 2016 Dec 2;81(1):62-68. Epub 2016 Dec 2.
    Tokyo CCU Network Scientific Committee.
    Background: Prolonged QRS duration (pQRSd) on electrocardiogram (ECG) is a strong predictor of poor outcome in heart failure, myocardial infarction, and myocarditis, but it is unclear whether pQRSd also predicts poor outcomes of takotsubo cardiomyopathy (TC).Methods and Results:Between 1 January 2010 and 31 December 2012, we retrospectively enrolled 299 patients with TC (mean age, 73.5±11. Read More

    Levosimendan accelerates recovery in patients with takotsubo cardiomyopathy.
    Cardiol J 2016 2;23(6):610-615. Epub 2016 Dec 2.
    Cardiology Department, Ordu University Education and Research Hospital, Ordu, Turkey Cardiology Department, Samsun Education and Research Hospital, Samsun, Turkey Cardiology Department, Van Yuzuncu Yıl University Medicine Faculty, Van, Turkey.
    Background: The aim of this study was to determine the efficacy and safety of levosimendan in takotsubo cardiomyopathy (TC).

    Methods: The study was conducted in a retrospective design and 42 consecutive patients were enrolled in 6 cardiovascular centers in Turkey. The records of TC patients having left ventricular ejection fraction (LVEF) £ 35% were examined at admission, discharge and recovery period including their clinical and echocardiographic data. Read More

    The natural history of takotsubo syndrome: a two-year follow-up study with myocardial sympathetic and perfusion G-SPECT imaging.
    Eur J Nucl Med Mol Imaging 2017 Feb 1;44(2):267-283. Epub 2016 Dec 1.
    Deptartment of Diagnostic Imaging, Nuclear Medicine Unit, N.O.P. - S. Stefano, U.S.L. Toscana Centro, via Suor Niccolina Infermiera 20, 59100, Prato, Italy.
    Purpose: To investigate changes in sympathetic activity, perfusion, and left ventricular (LV) functionality in takotsubo cardiomyopathy (TTC) patients from onset (T0) to post-onset conditions at 1 month (T1), 1-2 years (T2, T3).

    Methods: Twenty-two patients (70 ± 11 years) underwent serial gated single photon emission tomography (G-SPECT) studies with (123)I-mIBG and (99m)Tc-Sestamibi. Statistics were performed using ANOVA/Sheffé post-hoc, correlation test, and receiver operating characteristic (ROC) curve analysis (p < 0. Read More

    Manifestation of Latent Left Ventricular Outflow Tract Obstruction in the Acute Phase of Takotsubo Cardiomyopathy.
    Intern Med 2016;55(23):3413-3420. Epub 2016 Dec 1.
    Department of Cardiology, Niigata City General Hospital, Japan.
    Objective Left ventricular outflow tract (LVOT) obstruction is a complication in 15-25% of patients with Takotsubo cardiomyopathy and sometimes leads to catastrophic outcomes, such as cardiogenic shock or cardiac rupture. However, the underlying mechanisms have not been clarified. Methods and Results We experienced 22 cases of Takotsubo cardiomyopathy during 3 years, and 4 of these 22 cases were complicated with LVOT obstruction in the acute phase (mean age 79±5 years, 1 man, 21 women). Read More

    Extracorporeal membrane oxygenation for pheochromocytoma-induced cardiogenic shock.
    Ann Intensive Care 2016 Dec 28;6(1):117. Epub 2016 Nov 28.
    Intensive Care Unit, Institute of Cardiology, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Paris, France.
    Background: Pheochromocytoma, a rare catecholamine-producing tumor, might provoke stress-induced Takotsubo-like cardiomyopathy and severe cardiogenic shock. Because venoarterial-extracorporeal membrane oxygenation (VA-ECMO) rescue of pheochromocytoma-induced refractory cardiogenic shock has rarely been reported, we reviewed our ICU patients' presentations and outcomes.

    Methods: All pheochromocytoma-induced refractory cardiogenic shock cases managed with VA-ECMO (January 2007-March 2015) were prospectively included and reviewed. Read More

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