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    3215 results match your criteria Cardiomyopathy Takotsubo

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    Takotsubo cardiomyopathy after intravenous epinephrine administration following cardiac arrest provoked by pneumoperitoneum - a case report.
    Pol Merkur Lekarski 2017 Apr;42(250):165-169
    Józef Struś Hospital, Poznań, Poland: Department of General and Colorectal Surgery.
    In stress-induced takotsubo cardiomyopathy (TC) high levels of catecholamines, including epinephrine, may be detected in blood. On the other hand, administration of exogenous epinephrine may occasionally result in TC.

    A Case Report: The authors describe a case of a 58-year-old, otherwise healthy female, with TC which occurred after intravenous injection of 1 mg of epinephrine against cardiac arrest provoked by pneumoperitoneum performed before planned laparoscopic cholecystectomy. Read More

    Glycocalyx shedding is markedly increased during the acute phase of Takotsubo cardiomyopathy.
    Int J Cardiol 2017 Apr 28. Epub 2017 Apr 28.
    The Queen Elizabeth Hospital, Department of Cardiology, Australia; The University of Adelaide, Australia. Electronic address:
    Background: Acute myocardial infarction (AMI) and other forms of myocardial acute oxidative stress are associated with variable "shedding" of the endothelial glycocalyx (GCS) which can be quantitated ex vivo by release into plasma of glycocalyx components such as Syndecan-1 (SD-1). Previous studies have implicated release of both catecholamines and BNP as potential accentuating factors in GCS: since these are prominent aspects of the pathogenesis of Takotsubo cardiomyopathy (TTC), we hypothesised that TTC is associated with increased GCS and the extent of GCS is predictable on the basis of NT-proBNP and catecholamine releases.

    Methods: SD-1 concentrations were measured in 48 TTC patients acutely and after 3months, and compared with those in 12 healthy controls, and 17 patients with AMI. Read More

    Impact of myocardial bridging on in-hospital outcome in patients with takotsubo syndrome.
    J Cardiol 2017 May 15. Epub 2017 May 15.
    Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
    Background: Prevalence of myocardial bridging of the left anterior descending coronary artery (LAD) in patients with takotsubo syndrome (TTS) has been demonstrated. However, the impact of myocardial bridging on in-hospital outcome has not been fully evaluated.

    Methods: A total of 144 consecutive patients with TTS were enrolled. Read More

    Recurrent Stress Cardiomyopathy During COPD Exacerbation: Are Beta-adrenergic Agonists Only to Blame?
    Cureus 2017 Apr 14;9(4):e1166. Epub 2017 Apr 14.
    Cardiology, North Bronx Health Network Jacobi Medical Center.
    Takotsubo cardiomyopathy (TCM) is a variant of stress-induced cardiomyopathy, characterized by transient left ventricular dysfunction that may be associated with emotional or physical triggers. We present the case of a 51-year-old Caucasian female with severe chronic obstructive pulmonary disease (COPD) who presented with syncope and was found to have her second lifetime episode of stress-induced cardiomyopathy. Eight months prior, she had been admitted with a COPD exacerbation and was found to have left ventricular (LV) dysfunction with ejection fraction (EF) of 22% attributed to TCM with subsequent normalization of her left ventricular function. Read More

    Transient left ventricular outflow tract obstruction with systolic anterior motion of the mitral valve: A stunning cause.
    Echocardiography 2017 May 12. Epub 2017 May 12.
    Department of Cardiology, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands.
    Left ventricular outflow tract obstruction (LVOTO) and systolic anterior motion (SAM) of the mitral valve may have various etiologies, of which hypertrophic cardiomyopathy is the most common. More rarely, an acute coronary syndrome, myocardial stunning, and takotsubo cardiomyopathy may give rise to LVOTO and SAM. Here, we present a 70-year-old female patient with a non-ST-elevation acute coronary syndrome treated with percutaneous coronary intervention. Read More

    Comparison and Outcome Analysis of Patients with Takotsubo Cardiomyopathy Triggered by Emotional Stress or Physical Stress.
    Front Psychol 2017 27;8:527. Epub 2017 Apr 27.
    First Department of Medicine, Faculty of Medicine, University Medical Centre Mannheim, University of HeidelbergMannheim, Germany.
    Background: Previous studies revealed that takotsubo cardiomyopathy (TTC) is triggered by physical and emotional stresses. This study was performed to determine the short- and long-term prognostic impact of emotional- and physical stress associated with TTC. Methods and results: Our institutional database constituted a collective of 84 patients diagnosed with TTC between 2003 and 2015. Read More

    Drug-Induced Takotsubo Cardiomyopathy.
    J Cardiovasc Pharmacol Ther 2017 Jan 1:1074248417708618. Epub 2017 Jan 1.
    3 Gill Heart Institute, University of Kentucky HealthCare, Lexington, KY, USA.
    Background: The most plausible hypothesis for takotsubo cardiomyopathy (TCM) is a catecholamine surge. Direct administration of catecholamines or medications causing catecholamine surge is frequently used in clinical practice.

    Methods: A Medline/PubMed database search was conducted for case reports or series of drug-induced TCM. Read More

    Epinephrine-induced Takotsubo Cardiomyopathy During Laparoscopic Myomectomy: Case Report and Review of the Literature.
    J Minim Invasive Gynecol 2017 May 6. Epub 2017 May 6.
    Department of Obstetrics and Gynecology.
    Laparoscopic myomectomy, a minimally invasive procedure performed for the management of uterine leiomyomas involves a challenging aspect: excessive local bleeding. Hemorrhage control during laparoscopic myomectomy could be reached through the use of a wide range of vasoconstrictors including epinephrine. Epinephrine is frequently used for the control of local bleeding during surgery; however, it has been associated with several complications. Read More

    Adult T-cell leukemia-lymphoma complicated by Takotsubo cardiomyopathy and HTLV-1-associated myelopathy after treatment with the anti-CCR4 antibody mogamulizumab.
    Rinsho Ketsueki 2017 ;58(4):309-314
    Department of Hematology, Nippon Medical School.
    Adult T-cell leukemia-lymphoma (ATL) caused by human T-lymphotropic virus type 1 (HTLV-1) is generally associated with poor prognosis. The anti-CCR4 antibody mogamulizumab is one of the options for refractory or relapsed ATL. Mogamulizumab is intravenously administered as a single agent at a dose of 1. Read More

    Takotsubo cardiomyopathy after microwave ablation for metastatic liver lesions.
    Cardiovasc Revasc Med 2017 Apr 29. Epub 2017 Apr 29.
    CHVZ, University Hospital UZ Brussel, Brussels, Belgium.
    Takotsubo cardiomyopathy (TCMP) is characterized by transient and reversible left ventricular regional wall motion abnormalities triggered by acute and intense emotional or physical stress. We present a case of a 79 year old woman with a hypertensive crisis after microwave ablation (MWA) for metastatic liver lesions. Initial evaluation suggested an acute coronary syndrome with an ST segment elevation and with elevated serum troponin T. Read More

    DKA-Induced Takotsubo Cardiomyopathy in Patient with Known HOCM.
    Case Rep Crit Care 2017 3;2017:4287125. Epub 2017 Apr 3.
    Overlook Medical Center, Summit, NJ, USA.
    The first published case of Diabetic Ketoacidosis-induced Takotsubo cardiomyopathy was in 2009. Our patient is the 1st reported case of Diabetic Ketoacidosis- (DKA-) induced Takotsubo cardiomyopathy (TC) in a patient with known hypertrophic cardiomyopathy (HOCM) in the United States. In the literature, there are only two examples linking DKA to TC; however, this report focuses on the biochemical and physiological causes of TC in a patient with known HOCM and new-onset DKA. Read More

    Over the Exceptions: Psychiatric Disorder, Medical Stress, and Takotsubo Cardiomyopathy.
    J Cardiovasc Echogr 2017 Apr-Jun;27(2):66-70
    Cardiology and Cardiovascular Physiopathology, University of Perugia, Perugia, Italy.
    Exact natural history and physiopathology of takotsubo cardiomyopathy (TC) are incompletely understood. In the last years, a lot of special cases of TC appeared in the literature. This case report is a typical case of TC, which meets all Mayo Clinic diagnosis criteria, over the exceptions; its main feature is that it has both physical (medical) and emotional (psychiatric) triggers. Read More

    Why Is Reverse Takotsubo "Reverse"?
    South Med J 2017 May;110(5):381-385
    From the Department of Medicine, Division of Cardiology, Prof Dr C.C. Iliescu Institute of Cardiovascular Diseases, Bucharest, Romania, and the Department of Medicine, Office of Clinical Research, and the Department of Medicine, Division of Cardiology, University of Tennessee Health Science Center, Memphis.
    Objectives: Takotsubo cardiomyopathy (TTC) is an acute cardiac syndrome simulating myocardial infarction that is characterized by transient wall motion abnormalities in the absence of coronary artery obstruction. Reverse TTC (rTTC) is a recently described variant of TTC. This review defines and compares both forms of TTC, stating their resemblances and differences. Read More

    Takotsubo cardiomyopathy in amiodarone-induced hyperthyroidism.
    Endocrinol Diabetes Metab Case Rep 2017 15;2017. Epub 2017 Feb 15.
    Endocrinology Department, Parc Taulí Sabadell University Hospital, Sabadell Barcelona, Spain.
    Summary: Takotsubo cardiomyopathy (TC) is an atypical, severe but reversible form of acute heart insufficiency. It typically presents with left ventricular failure, transient apical and mid-segments hypokinesis, absence of significant coronary stenosis and new electrographic abnormalities and/or elevation in serum cardiac enzymes. Although TC ('broken heart syndrome') has classically been associated with emotional trauma, evidence suggests that other precipitants might exist, including iatrogenic and thyroid-mediated forms. Read More

    Hydrogen sulfide attenuates cardiac injury in takotsubo cardiomyopathy by alleviating oxidative stress.
    Nitric Oxide 2017 Jul 24;67:10-25. Epub 2017 Apr 24.
    Department of Physiology, Hebei Medical University, Shijiazhuang 050017, China; Hebei Collaborative Innovation Center for Cardio-Cerebrovascular Disease, Shijiazhuang 050017, China; Key Laboratory of Vascular Medicine of Hebei Province, Shijiazhuang 050017, China. Electronic address:
    Takotsubo cardiomyopathy (TCM) is characterized by transient left ventricular apical ballooning with the absence of coronary occlusion, which is an acute cardiac syndrome with substantial morbidity and mortality. It was reported that reduced endogenous hydrogen sulfide (H2S) levels may be related to various heart diseases. The present study investigated the mechanism by which H2S administration modulates and protects cardiac function in TCM rats. Read More

    Exploring the Pathophysiology of Takotsubo Cardiomyopathy.
    Curr Cardiol Rep 2017 Jun;19(6):53
    Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 S. Greene street, Baltimore, MD, 21201, USA.
    Purpose Of Review: The purpose of this review is to explore the pathophysiology of Takotsubo cardiomyopathy by appraising the interplay between myocardial perfusion, function, metabolism, and, particularly, sympathetic innervation.

    Recent Findings: A number of hypotheses have been proposed to explain the pathogenesis of Takotsubo cardiomyopathy, which include (1) catecholamine cardiac toxicity, (2) myocardial sympathetic innervation disruption, (3) coronary vasospasm, (4) myocardial microvascular dysfunction, and (5) aborted myocardial infarction. These proposals are primarily derived from findings of nuclear myocardial perfusion, metabolism, and cardiac sympathetic innervation imaging. Read More

    Use of an argatroban-based purge solution in a percutaneous ventricular assist device.
    Am J Health Syst Pharm 2017 May;74(9):e163-e169
    Department of Pharmacy Practice and Science, University of Maryland School of Pharmacy, Baltimore, MD.
    Purpose: The use of an argatroban-based percutaneous ventricular assist device (pVAD) purge solution in a patient with suspected heparin-induced thrombocytopenia (HIT) is described.

    Summary: A 70-year-old woman in cardiogenic shock was admitted to a coronary care unit after being discovered unresponsive at home. A transthoracic echocardiogram revealed a low ejection fraction and findings consistent with takotsubo cardiomyopathy. Read More

    Multiple sclerosis broke my heart.
    Ann Neurol 2017 May 9;81(5):754-758. Epub 2017 May 9.
    Neurology, Multiple Sclerosis, Myelin Disorders and Neuroinflammation, Pierre Wertheimer Neurological Hospital, Hospices Civils de Lyon, Lyon/Bron.
    We report 5 cases of acute heart failure (AHF) related to multiple sclerosis (MS) relapses. AHF was inaugural in 3 patients, always preceded or accompanied by signs of brainstem dysfunction; it was severe, requiring intensive care management. Echocardiography showed left ventricular hypokinesis. Read More

    Cumulative Impact of Stressful Life Events on the Development of Takotsubo Cardiomyopathy.
    Ann Behav Med 2017 Apr 17. Epub 2017 Apr 17.
    Department of Medicine, Brown University Medical School and The Miriam Hospital, Providence, RI, USA.
    Background: The role of stressful life events in the onset of Takotsubo cardiomyopathy (TC) is unclear.

    Purpose: This study sought to examine associations between type, timing, and number of stressful life events and onset of TC.

    Methods: A case-control study conducted among consecutive incident female TC cases and myocardial infarction (MI) controls admitted to two emergency departments in New England. Read More

    Aborted Sudden Cardiac Death in a Female Patient Presenting with Takotsubo-Like Cardiomyopathy due to Epicardial Coronary Vasospasm.
    Case Rep Cardiol 2017 19;2017:7875240. Epub 2017 Mar 19.
    Department of Cardiology & Vascular Medicine, GRN Hospital Weinheim, Weinheim, Germany.
    Takotsubo cardiomyopathy is characterized by apical ballooning of the left ventricle (LV) in the absence of relevant coronary artery stenosis, which typically occurs in elderly women after emotional stress. Catecholamine cardiotoxicity, metabolic disturbance, and coronary microvascular impairment have previously been proposed as underlying pathophysiologic mechanisms of takotsubo cardiomyopathy, whereas myocardial stunning resulting from epicardial coronary artery vasospasm is not generally accepted as a cause of takotsubo cardiomyopathy. The prognosis of takotsubo cardiomyopathy is generally more favourable compared to myocardial infarction; however, severe complications such as rupture of the LV and life-threatening arrhythmias may occur. Read More

    Can takotsubo cardiomyopathy be diagnosed by autopsy? Report of a presumed case presenting as cardiac rupture.
    BMC Clin Pathol 2017 5;17. Epub 2017 Apr 5.
    Departments of Medicine, Maisonneuve-Rosemont Hospital, 5415 Boulevard de L'Assomption, Montreal, Quebec H1T 2M4 Canada.
    Background: Takostsubo (stress) cardiomyopathy (TC) is a clinical syndrome featuring transient left ventricular dysfunction and wall-motion abnormalities, usually following emotional or physical stress. The diagnosis of TC depends on fulfillment of multiple clinical criteria. Although the pathogenesis has not been firmly established, myocardial cathecholamine toxicity is thought to represent a primary mechanism. Read More

    Takotsubo Cardiomyopathy in a Patient with Undiscovered Sigmoid Colon Cancer.
    Case Rep Cardiol 2017 9;2017:4563203. Epub 2017 Mar 9.
    Department of Cardiology, Chi-Mei Medical Center, Liuoying, Taiwan.
    Takotsubo cardiomyopathy (TTC) is a stress-related cardiomyopathy that is characterized by reversible left systolic dysfunction, which appears to be precipitated by sudden emotional or physical stress in the absence of myocardial infarction. Here we present a rare case that clinically presented with intermittent abdominal pain, initially impressed as non-ST elevation myocardial infarction and congestive heart failure but with a normal coronary angiogram. Her symptoms relieved spontaneously without returning. Read More

    FOLFOX Induced Takotsubo Cardiomyopathy Treated with Impella Assist Device.
    Case Rep Cardiol 2017 7;2017:8507096. Epub 2017 Mar 7.
    Cardiology, University of Miami, Palm Beach Regional Consortium, Atlantis, FL, USA.
    Chemotherapy induced cardiotoxicity is becoming increasingly prevalent with several new agents being used recently. The incidence of Takotsubo cardiomyopathy due to 5-fluorouracil based chemotherapeutic regimens like FOLFOX is not uncommon. It is also seen with platinum based chemotherapy. Read More

    Conventional Coronary Angiography Induced Takotsubo Cardiomyopathy Complicated with Cardiac Tamponade.
    Case Rep Cardiol 2017 1;2017:5631264. Epub 2017 Mar 1.
    Division of Cardiology, Department of Internal Medicine, Gyeongsang National University and Gyeongsang National University Hospital, Jinju, Republic of Korea.
    Takotsubo cardiomyopathy (TCM) is a transient left ventricular dysfunction that typically occurs after emotional or physical stress. TCM has a benign prognosis and serious complications are uncommon. However, though very rarely reported, cardiac tamponade has occurred on some occasions. Read More

    Prognostic Significance of Early Rehospitalization After Takotsubo Cardiomyopathy.
    Am J Cardiol 2017 May 1;119(10):1572-1575. Epub 2017 Mar 1.
    Department of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
    Short-term complications, particularly rehospitalization, after a diagnosis of takotsubo cardiomyopathy (TTC) are poorly described. We sought to characterize the rates, causes, clinical associations, and prognostic implications of early rehospitalization in this patient population. We performed a retrospective observational study of all adult subjects diagnosed with TTC at an academic tertiary care hospital from 2005 to 2015. Read More

    Coincidental coronary artery disease impairs outcome in patients with takotsubo cardiomyopathy.
    QJM 2017 Mar 14. Epub 2017 Mar 14.
    From the First Department of Medicine Cardiology, University Medical Centre Mannheim (UMM), Faculty of Medicine Mannheim, University of Heidelberg, Mannheim, Germany and DZHK (German Centre for Cardiovascular Research) Partner Site Mannheim, Mannheim, Germany.
    Background And Aim: Takotsubo cardiomyopathy (TC) is an important differential diagnosis of coronary artery disease (CAD), mimicking acute coronary syndrome in clinical symptoms, biomarker profiles and ST-elevation in ECG. Absence of occlusive coronary disease is an essential criterion distinguishing both diseases. The aim of the study was to explore the influence of co-existing incidental CAD on poorer clinical outcomes and all-cause mortality in TC. Read More

    Takotsubo cardiomyopathy in amyotrophic lateral sclerosis.
    J Neurol Sci 2017 Apr 8;375:289-293. Epub 2017 Feb 8.
    Department of Neurology, Seoul National University Hospital, Seoul, Republic of Korea. Electronic address:
    Objective: To investigate the frequency, features, and prognosis of takotsubo cardiomyopathy (TTC) in patients with amyotrophic lateral sclerosis (ALS).

    Methods: We reviewed detailed clinical, laboratory, and cardiovascular data from 64 ALS patients (38 men and 26 women) who underwent echocardiographic evaluation for various reasons at a single referral center between January 2011 and December 2015.

    Results: TTC was diagnosed in 9 ALS patients (4 men and 5 women). Read More

    Prevalence of cancer in Takotsubo cardiomyopathy: Short and long-term outcome.
    Int J Cardiol 2017 Jul 22;238:159-165. Epub 2017 Feb 22.
    First Department of Medicine, Faculty of Medicine, University Medical Centre Mannheim (UMM), University of Heidelberg, Mannheim, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site, Heidelberg-Mannheim, Mannheim, Germany.
    Background: Takotsubo Cardiomyopathy (TTC) is a transient disorder of ventricular wall dysfunction, mostly induced by physical or emotional stress. TTC may be associated with adverse cardiac events. The association of cancer and its clinical impact in TTC patients has not been described yet. Read More

    [Gender and cardiovascular diseases : Why we need gender medicine].
    Internist (Berl) 2017 Apr;58(4):336-343
    Institut für Geschlechterforschung in der Medizin (GiM), Charité - Universitätsmedizin Berlin, Hessische Str. 3-4, 10115, Berlin, Deutschland.
    Gender medicine is concerned with the question of why diseases are expressed differently in the genders. It takes differences between men and women into account, which are often neglected by traditional medicine. Sex differences can also be found in cardiovascular diseases; therefore, risk factors for cardiovascular diseases have a different significance depending on the sex. Read More

    Gender Differences in Post-Traumatic Stress.
    Biores Open Access 2017 1;6(1):7-14. Epub 2017 Feb 1.
    Dipartimento Emergenza-Urgenza, UNIMORE , Modena, Italy .
    Acute stress can trigger cardiovascular events and disease. The earthquake is an "ideal" natural experiment for acute and chronic stress, with impact mainly on the cardiovascular system. On May 20th and 29th, 2012, two earthquakes of magnitude 5. Read More

    Low MMP-8/TIMP-1 reflects left ventricle impairment in takotsubo cardiomyopathy and high TIMP-1 may help to differentiate it from acute coronary syndrome.
    PLoS One 2017 9;12(3):e0173371. Epub 2017 Mar 9.
    Heart and Lung Center, Helsinki University Hospital and Helsinki University, Helsinki, Finland.
    Background: Matrix metalloproteinase 8 (MMP-8) is the most potent type-I collagen protease. Such collagen mainly constitutes the transient fibrosis in takotsubo cardiomyopathy (TTC) endomyocardial biopsies. High MMP-8 and tissue-inhibitor of matrix metalloproteinase-1 (TIMP-1) levels are implicated in acute coronary syndrome (ACS). Read More

    The Role of Early Focused Cardiac Ultrasound in a Not-So-Typical Presentation of Takotsubo Cardiomyopathy: A Case Report.
    J Emerg Med 2017 May 3;52(5):e169-e173. Epub 2017 Mar 3.
    Department of Emergency Medicine, Bridgeport Hospital, Bridgeport, Connecticut.
    Background: Focused cardiac ultrasound (FoCUS) can be extremely helpful in identifying unexpected diagnoses that can significantly alter treatment options. The diagnosis of Takotsubo cardiomyopathy (TCM) may be difficult to identify.

    Case Report: We describe a 47-year-old woman who presented to the emergency department (ED) with atypical features of TCM. Read More

    Discrimination of stress (Takotsubo) cardiomyopathy from acute coronary syndrome with clinical risk factors and coronary evaluation in real-world clinical practice.
    Int J Cardiol 2017 May 22;235:154-161. Epub 2017 Feb 22.
    Division of Cardiology, Department of Internal Medicine/Cardiovascular Center, Seoul National University Hospital, Seoul, Republic of Korea.
    Background: Diagnosing stress cardiomyopathy (SCMP) apart from acute coronary syndrome (ACS) is challenging since coronary evaluation is not always feasible in real-world clinical practice. We explored the current practice pattern of coronary evaluation in patients suspected to have SCMP and divulged the distinguishable features of SCMP from ACS.

    Methods And Results: From 2010 to 2015, only 219 out of 691 (32%) hospitalized patients suspected to have SCMP have received coronary evaluation in two tertiary hospitals. Read More

    Left ventricular myocardial function assessed by three-dimensional speckle tracking echocardiography in Takotsubo cardiomyopathy.
    Echocardiography 2017 Apr 7;34(4):523-529. Epub 2017 Mar 7.
    Department of Cardiology, The Sakakibara Heart Institute of Okayama, Okayama, Japan.
    Background: We aimed to investigate left ventricular (LV) functional recovery in Takotsubo cardiomyopathy (TC) using three-dimensional (3D) speckle tracking echocardiography.

    Methods: Twenty-one patients with TC who underwent routine and 3D echocardiography as well as electrocardiography were enrolled. 3D images were analyzed to measure 3D radial strain and area tracking (area change of each LV segment). Read More

    Physically triggered Takotsubo cardiomyopathy has a higher in-hospital mortality rate.
    Int J Cardiol 2017 May 23;235:87-93. Epub 2017 Feb 23.
    Department of Cardiology, Fujita Health University School of Medicine, Toyoake, Japan.
    Background: Takotsubo cardiomyopathy (TC) is a myopathy triggered by severe stressful events. However, little is known about the determinants of in-hospital outcomes. We prospectively determined the effect of different triggers on the prognosis of TC. Read More

    Takotsubo cardiomyopathy secondary to spontaneous right-sided pneumothorax.
    BMJ Case Rep 2017 Mar 1;2017. Epub 2017 Mar 1.
    Department of Cardiology, University of Missouri Kansas City School of Medicine, Kansas City, Missouri, USA.
    Takotsubo cardiomyopathy (TCM) is a unique type of cardiomyopathy characterised by left ventricular systolic dysfunction in association with stressful conditions. Patients with this condition usually present with chest pain and dyspnoea, and the presentation can mimic acute coronary syndrome. We present a case of a woman aged 58 years who presented with progressive dyspnoea and cough. Read More

    Surgical treatment of left ventricular wall rupture, regarded as a consequence of Takotsubo cardiomyopathy.
    SAGE Open Med Case Rep 2017 18;5:2050313X16689210. Epub 2017 Jan 18.
    Scientific Research Institute of Heart Surgery and Organ Transplantation, Bishkek, Kyrgyzstan.
    Objective: We present the case of possible reverse type of TCM in a female patient presented with progressive left ventricular dysfunction and its rupture in pericardium.

    Methods: The detailed history, physical examination, laboratory tests, electrocardiography, serial echocardiography, coronary angiography with left ventriculography were performed to diagnose possible Takotsubo cardiomyopathy in 63-year old woman admitted to our center with complaints of dyspnea, lightheadedness, weakness and signs of hypotension and history of inferior myocardial infarction, acute left ventricular aneurysm, and effusive pericarditis and pleuritis, developed after emotional stress 5 months ago.

    Results: Clinical evaluation revealed unremarkable laboratory tests, normal troponin values, signs of old inferior myocardial infarction on electrocardiogram, and left ventricular (LV) dilatation and dysfunction, akinesia of LV infero-lateral wall with thinning and its rupture and blood shunting in pericardium. Read More

    Stress cardiomyopathy in a patient with hypertrophic cardiomyopathy and myocardial bridging.
    BMJ Case Rep 2017 Feb 21;2017. Epub 2017 Feb 21.
    Department of Ecocardiography, Columbia University, Miami Beach, Florida, USA.
    Stress cardiomyopathy is an acquired cardiomyopathy of unknown aetiology. It usually occurs in women over the age of 70 who have experienced physical or emotional stress. It is most commonly characterised by a transient, left ventricular systolic dysfunction in the apical portion and hyperkinesia in the basal segments, without obstructive coronary artery disease. Read More

    Recurrence of Postoperative Stress-Induced Cardiomyopathy Resulting from Status Epilepticus.
    Case Rep Crit Care 2017 22;2017:8063837. Epub 2017 Jan 22.
    Department of Critical Care Medicine, Naval Medical Center Portsmouth, Portsmouth, VA, USA.
    Introduction. Classically, stress-induced cardiomyopathy (SIC), also known as takotsubo cardiomyopathy, displays the pathognomonic feature of reversible left ventricular apical ballooning without coronary artery stenosis following stressful event(s). Temporary reduction in ejection fraction (EF) resolves spontaneously. Read More

    Early treatment with isoflurane attenuates left ventricular dysfunction and improves survival in experimental Takotsubo.
    Acta Anaesthesiol Scand 2017 Apr 10;61(4):399-407. Epub 2017 Feb 10.
    The Department of Anaesthesiology and Intensive Care Medicine, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
    Background: Takotsubo syndrome (TS) is an acute cardiac condition, often triggered by critical illness, for which no specific treatment exists. Previously, we showed that isoflurane can prevent experimental TS. The aim of this study was to evaluate the potential treatment effects of isoflurane. Read More

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