250 results match your criteria Cardiomyopathy Cocaine


Apical Hypertrophic Cardiomyopathy Prompting Aneurysm, Thrombus, and Cardiac Arrest in a 56-Year-Old Female.

Cureus 2022 Jun 18;14(6):e26067. Epub 2022 Jun 18.

Cardiology, Lincoln Medical Center, New York City, USA.

Hypertrophic cardiomyopathy (HCM) is the most prevalent genetic cardiac disease while apical hypertrophic cardiomyopathy (apHCM) is a rare subset of HCM. The significance of this case report is to present apHCM, its chronological course, and its association with left ventricular aneurysm, thrombosis, and cardiac arrest. We present the case of a 56-year-old female with a past medical history of apHCM who was admitted for substernal chest pain, developed a ventricular storm (VT), and subsequently suffered cardiac arrest; resuscitation of spontaneous circulation (ROSC) was eventually achieved after 10 minutes. Read More

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Profound Vagal Tone and Bradycardia Mimicking Asystole: A Resuscitation Case Report.

Case Rep Cardiol 2022 8;2022:4759950. Epub 2022 Mar 8.

Cardiology Department, Tipperary University Hospital, Clonmel, Tipperary, Ireland.

A 48-year-old man presented with dizziness. When he arrived at the emergency department, he collapsed and became pulseless. Prior to his collapse, he was asymptomatic and now even participated in multiple marathon and ultra-running events per year. Read More

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Heavy Burden of Toxic Dilated Cardiomyopathy Among Young Adults: A Retrospective Study and Review of the Literature.

Can J Cardiol 2022 01 11;38(1):49-58. Epub 2021 Nov 11.

Institut Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Québec City, Québec, Canada. Electronic address:

Background: Dilated cardiomyopathy (DCM) is a well described entity for heart failure (HF) with reduced left ventricular ejection fraction (LVEF). Recently, drugs and other substance of abuse have been recognised as potential triggers for DCM. The aim of this study was to assess the survival in patients ≤ 65 years of age with toxic cardiomyopathy (TCM). Read More

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January 2022

Cardiac Complications of Common Drugs of Abuse: Pharmacology, Toxicology, and Management.

Can J Cardiol 2021 Nov 1. Epub 2021 Nov 1.

Department of Medicine and Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada. Electronic address:

Cardiovascular complications from drugs of abuse are becoming more apparent because of increased usage worldwide. Substance abuse can cause acute and chronic cardiovascular complications and is increasing in prevalence especially in young adults. These substances contribute to the development of acute coronary syndrome, type 2 myocardial injury, arrhythmias, and cardiomyopathies, and have numerous other cardiovascular complications. Read More

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November 2021

Changing Incidence and Mechanism of Pregnancy-Associated Myocardial Infarction in the State of California.

J Am Heart Assoc 2021 11 20;10(21):e021056. Epub 2021 Oct 20.

Department of Internal Medicine and Cardiology University of California Riverside School of Medicine Riverside CA.

Background The objective of this study was to evaluate the temporal trends in pregnancy-associated myocardial infarction (PAMI) in the State of California and explore potential risk factors and mechanisms. Methods and Results The California State Inpatient Database was analyzed from 2003 to 2011 for patients with () codes for acute myocardial infarction and pregnancy or postpartum admissions; risk factors were analyzed and compared with pregnant patients without myocardial infarction. A total of 341 patients were identified with PAMI from a total of 5 266 380 pregnancies (incidence of 6. Read More

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November 2021

Reverse Takotsubo Cardiomyopathy Precipitated by Chronic Cocaine and Cannabis Use.

Cardiovasc Toxicol 2021 12 24;21(12):1012-1018. Epub 2021 Aug 24.

Drug Health Services, Royal Prince Alfred Hospital, Level 6, King George V Building, 83-117 Missenden Road, Camperdown, NSW, 2050, Australia.

This case report describes a 31-year-old man with 10 years of cocaine and cannabis dependence who developed reverse Takotsubo cardiomyopathy (rTC), a rare variant of Takotsubo cardiomyopathy. He presented to the Emergency Department (ED) with severe left temporal headache and vomiting which began whilst smoking cannabis and several hours after smoking methamphetamine and using cocaine via insufflation. Computed tomography and angiography of the brain was normal, and the headache resolved with analgesia. Read More

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December 2021

A 33-year-old man with a history of recurrent pneumonia presenting with hypoxemic respiratory failure.

Allergy Asthma Proc 2021 Sep 13;42(5):439-442. Epub 2021 Jul 13.

The patient was a 33-year-old man with a history of recurrent pneumonia, autism, bipolar disorder, hypothyroidism, intermittent asthma, and nonischemic cardiomyopathy attributed to cocaine use who was admitted with hypoxemic respiratory distress with bilateral infiltrates seen on a chest radiograph. He was treated for community-acquired pneumonia but progressed to respiratory failure that required intubation and broad-spectrum antibiotic therapy. His medical history was notable for short stature, abnormal facial features, and, since childhood, at least two pneumonias per year that required antibiotics. Read More

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September 2021

Cocaine induced heart failure: report and literature review.

J Community Hosp Intern Med Perspect 2021 Jun 21;11(4):547-550. Epub 2021 Jun 21.

Department of Internal Medicine, Division of Cardiology, Trinitas Regional Medical Center, Elizabeth, NJ, USA.

Heart failure is a complex clinical syndrome associated with high mortality and morbidity, creating a major public healthcare problem. It has a variety of etiologies, including substance abuse. Cocaine-induced cardiotoxicity is caused by direct effects of inhibition of sodium channels and indirect effects by inhibiting catecholamine uptake leading to increased sympathetic activity. Read More

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Drugs of Abuse and Heart Failure.

J Card Fail 2021 11 13;27(11):1260-1275. Epub 2021 Jun 13.

Duke Clinical Research Institute, Durham, North Carolina; Division of Cardiology, Duke University School of Medicine, Durham, North Carolina.

Substance use is common among those with heart failure (HF) and is associated with worse clinical outcomes. Alcohol, tobacco, cannabis, and cocaine are commonly abused substances that can contribute to the development and worsening of HF. Heavy alcohol consumption can lead to dilated cardiomyopathy, whereas moderate intake may decrease incident HF. Read More

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November 2021

Atypical presentation of Takayasu aortitis and myocarditis contributing to sudden death in a young Canadian first nations adult.

Cardiovasc Pathol 2021 Sep-Oct;54:107347. Epub 2021 May 24.

Department of Pathology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address:

This is a rare presentation of Takayasu arteritis in a 30-year-old Canadian First Nations woman with cardiac and aortic root-predominant disease, which manifested in complete heart block. She had a past medical history significant for substance misuse. At presentation, cardiac magnetic resonance imaging identified diffuse thickening of the left atrium and ventricular outflow tract with left ventricular cavity dilation and preserved systolic function. Read More

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December 2021

Psoriasis as risk factor for non-ischemic dilated cardiomyopathy: a population-based cross-sectional study.

BMC Cardiovasc Disord 2021 03 31;21(1):161. Epub 2021 Mar 31.

Department of Cardiology, Jersey Shore University Medical Center, Neptune, NJ, USA.

Background: Psoriasis is a chronic inflammatory skin condition commonly associated with psoriatic arthritis, malignancy, diabetes, inflammatory bowel disease, and cardiovascular disease. Several reports and studies have reported an association between psoriasis and non-ischemic dilated cardiomyopathy (NIDCM). We aim to study the relationship between psoriasis and non-ischemic dilated cardiomyopathy in a large population-based study. Read More

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Cocaine, cardiomyopathy, and heart failure: a systematic review and meta-analysis.

Sci Rep 2020 11 13;10(1):19795. Epub 2020 Nov 13.

Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.

Although the cardiotoxic effects of cocaine are universally recognized, the association between cocaine and cardiomyopathy and/or heart failure is poorly understood. To conduct a comprehensive review and meta-analysis on the association between cocaine, heart failure, and cardiomyopathy, we first conducted a broad-term search in PubMed, Embase, Web of Science, and Scopus for human studies containing primary data on the relationship between cocaine and heart failure or cardiomyopathy. We were interested in studies with data beyond acute coronary syndromes. Read More

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November 2020

Identification and analysis of miRNAs in the normal and fatty liver from the Holstein dairy cow.

Anim Biotechnol 2022 Jun 24;33(3):468-479. Epub 2020 Aug 24.

Development Planning Office, Henan University of Science and Technology, Luoyang, China.

MicroRNAs (miRNAs) are a class of non-coding short RNAs with ∼22 nts in length, which play important roles in the regulation of numerous biological processes in animals. In this study, two small RNA libraries from fatty (S01) and normal livers (S02) from Holstein Dairy Cow (HDC) were sequenced through deep sequencing. A total of 12,964,411 and 15,426,289 clean reads were obtained, representing 370 known and 182 novel miRNAs, respectively. Read More

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The cardiovascular health of prisoners who use cannabis: An exploratory study among hospitalised prisoners.

Therapie 2020 Nov - Dec;75(6):579-589. Epub 2020 Jul 9.

Pharmacoepidemiology research team, INSERM 1027, university of Toulouse, 31000 Toulouse, France; Addictovigilance center, department of medical and clinical pharmacology, Toulouse university hospital, 31000 Toulouse, France. Electronic address:

Objective: It is essential that health professionals who practice medicine in prison rely on accurate knowledge about their patients to provide them with adapted care. The use of cannabis can influence the health status of prisoners, but data are lacking regarding the potentially related adverse health consequences. The objective of this descriptive study was to describe the cardiovascular outcomes related to cannabis use in prisoners from several detention centres hospitalised in a French hospital. Read More

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September 2021

Cocaine-induced myocarditis.

Med Clin (Barc) 2021 06 14;156(12):631-632. Epub 2020 Jul 14.

Servicio de Radiodiagnóstico, Hospital Universitario Río Hortega, Valladolid, España.

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Slow on the Uptake, Progression to Heartbreak.

J Investig Med High Impact Case Rep 2020 Jan-Dec;8:2324709620936832

Emory University, Atlanta, GA, USA.

The prevalence of serotonin syndrome increases over the past several years as more serotonergic medications are being used in clinical practice. It is a potentially lethal condition caused by excessive serotonergic activity. Common causes of serotonin syndrome are the use of prescription medications, illicit drugs, or a combination of substances, leading to an increase in the activity of serotonin in the central and peripheral nervous system. Read More

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Prevalence, trends and in-hospital outcomes of takotsubo syndrome among United States cannabis users.

Int J Cardiol 2020 10 6;316:43-46. Epub 2020 Jun 6.

Division of Cardiology, Atlanta VA Medical Center, Decatur, GA, USA; Division of Cardiology, Medical College of Georgia, Augusta, GA, USA; Division of Cardiology, Morehouse School of Medicine, Atlanta, GA, USA.

Background: Recent reports suggest a link between increased cannabis (marijuana) use and stress-cardiomyopathy (Takotsubo Syndrome, TTS) and related complications. Amidst recent trends in cannabis legalization and a paucity of data, it remains essential to evaluate the prevalence, trends and outcomes of TTS in cannabis users on a large-scale.

Method: We studied prevalence and trends in TTS among adult cannabis users vs. Read More

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October 2020

Cardiac magnetic resonance in cocaine-induced myocardial damage: cocaine, heart, and magnetic resonance.

Heart Fail Rev 2022 01;27(1):111-118

Fondazione Toscana Gabriele Monasterio, Via Giuseppe Moruzzi, 156124, Pisa, Italy.

The use of cocaine constitutes a major health problem. Cocaine use is associated with acute and chronic complications that might involve any system, the most common being the cardiovascular system. The precise incidence of cocaine-induced cardiomyopathy remains mysterious and probably underreported. Read More

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January 2022

Beta Blocker Therapy in Heart Failure Patients with Active Cocaine Use: A Systematic Review.

Cardiol Res Pract 2020 8;2020:1985379. Epub 2020 May 8.

Division of Cardiology, New York Medical College, Metropolitan Hospital Center, New York, NY 10029, USA.

Background: Cocaine use is associated with multiple cardiovascular complications including heart failure. The use of different types of beta blockers in heart failure patients with active cocaine use is still a matter of debate. In this review, our objective is to systematically review the available literature regarding the use of beta blockers in the treatment of heart failure patients with concurrent cocaine use. Read More

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Recent advances in three-dimensional electroanatomical mapping guidance for the ablation of complex atrial and ventricular arrhythmias.

J Interv Card Electrophysiol 2021 Jun 26;61(1):37-43. Epub 2020 May 26.

Cardiology and Arrhythmology Clinic, University Hospital "Ospedali Riuniti Umberto I - Lancisi - Salesi", Ancona, Italy.

Purpose: To provide a brief overview of some relevant technological advances in the field of three-dimensional electroanatomical mapping (3D-EAM) that have recently entered the clinical arena and their role in guiding catheter ablation (CA) of complex atrial and ventricular arrhythmias.

Methods: In this technical report, we describe the general features of three novel algorithms featured in the updated CARTO PRIME™ mapping module for CARTO®3 version 7 3D-EAM system (Biosense Webster Inc., Diamond Bar, CA, USA): local activation time (LAT) hybrid, coherent mapping and map replay modules. Read More

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Acute Coronary Syndrome: Common Complications and Conditions That Mimic ACS.

FP Essent 2020 Mar;490:29-34

Womack Army Medical Center Cardiology, Bldg 4-2817 2817 Reilly Road, Fort Bragg, NC 28310.

Complications after acute myocardial infarction (MI) can be serious and potentially life-threatening. Coronary reperfusion therapy and revascularization can reduce the risk of these complications, but they still occur. Arrhythmias and conduction abnormalities are among the most common complications, and occur most often in hemodynamically unstable patients. Read More

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[Cocaine-induced acute myocarditis].

Ann Cardiol Angeiol (Paris) 2019 Nov 23;68(5):367-370. Epub 2019 Sep 23.

Service de cardiologie, centre hospitalier d'Avignon, 305, rue Raoul-Follereau, 84000 Avignon, France.

Cocaine is a potent sympathomimetic drug usually associated with cardiotoxicity, including ventricular arrhythmia, systemic hypertension and acute myocardial infarction. It constitutes the most frequent cause of drug-related death reported by medical examiners in the US, and these events are most often related to the cardiovascular manifestations of the drug. However; to the best of our knowledge; cocaine induced acute myocarditis has very rarely been reported. Read More

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November 2019

Association of recreational drug consumption, cardiac toxicity and heart transplantation

Can J Surg 2019 10;62(5):356-357

From the Department of Cardiac Surgery, Montreal Heart Institute and Université de Montréal, Montreal, Que. (Carrier); and the Department of Medicine, Montreal Heart Institute and Université de Montréal, Montreal, Que. (Giraldeau, Parent, Ducharme).

Summary: Cardiac toxicity from recreational drug use remains difficult to establish. We report the cases of 3 young patients who were hospitalized for cardiogenic shock. All were bridged to transplantation with implantation of a left ventricular assist device (LVAD). Read More

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October 2019

Diffuse myocardial calcification in a drug addict, complicating advanced life support.

J Pak Med Assoc 2019 Sep;69(9):1372-1375

Bezmialem Vakif University, TURKEY.

Myocardial calcification is a rare echocardiographic finding, which is often found in patients who have suffered from a myocardial infarction. Rarely, myocardial calcification may be present in individuals without a significant medical history. Until today, there has not been a published case report emphasising the relation between myocardial calcification and cocaine usage. Read More

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September 2019

[Hypoxic hepatitis in a patient with endomyocardial fibrosis].

Medicina (B Aires) 2019 ;79(4):284-286

Servicio de Salud Mental, Instituto de Investigaciones Médicas Alfredo Lanari, Universidad de Buenos Aires, Argentina.

Endomyocardial fibrosis is a restrictive cardiomyopathy with high morbidity and mortality rates, prevalent in the sub-Saharan Africa region but infrequent in our population. It has a close relation with blood hypereosinophilia. Hypoxic hepatitis is frequently observed in intensive care units and its diagnosis is clinical. Read More

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September 2019

A Case of Isolated Left Ventricular Non-Compaction Cardiomyopathy in a HIV Patient Presenting With Acute Heart Failure.

Cardiol Res 2019 Aug 31;10(4):236-240. Epub 2019 Jul 31.

Department of Medicine, BronxCare Hospital Center, Bronx, NY 10457, USA.

The etiology of cardiomyopathy in a HIV patient is multifactorial. Identifying the etiology of cardiomyopathy in a HIV patient needs extensive evaluation. Common causes include ischemic cardiomyopathy, myocarditis due to viral infections and opportunistic infections, cocaine abuse, alcoholic heart disease, drug toxicity or due to nutritional deficiencies. Read More

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Transient Left Ventricular Acute Failure after Cocaine Use.

Curr Drug Res Rev 2019 ;11(2):142-144

Department of Anesthesiology and Intensive Care, Hopital d'Instruction des Armees Sainte-Anne, Toulon, France.

Background: Cocaine is one of the most widely used illicit drugs, and it is the most common cause of drug-related death. The association of cocaine use with acute heart failure is a rare occurrence.

Case Report: We report the case of a 31 years-old woman who presented Takotsubo cardiomyopathy with severe cardiogenic shock after cocaine abuse. Read More

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Cocaine Abuse: An Attack to the Cardiovascular System-Insights from Cardiovascular MRI.

Radiol Cardiothorac Imaging 2019 Jun 13;1(2):e180031. Epub 2019 Jun 13.

Department of Radiological, Oncological and Anatomopathological Sciences, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.

Cocaine is the most commonly used illicit drug in the European Union. Its cardiac effects are numerous and diverse, both in acute and chronic abuse, and include myocardial infarction, myocarditis, catecholamine-induced cardiomyopathy, and chronic cardiomyopathy (subclinical, hypertrophic, and dilated phases). Their clinical manifestations are vastly overlapping, and differential diagnosis should be performed using a thorough diagnostic workup featuring clinical history, laboratory tests, electrocardiography, stress test, noninvasive imaging modalities, and coronary angiography. Read More

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Can acute stress be fatal? A systematic cross-disciplinary review.

Stress 2019 05 15;22(3):286-294. Epub 2019 Feb 15.

b Psychiatric Centre Copenhagen, Department O, Rigshospitalet , Copenhagen University Hospital ,  Copenhagen , Denmark.

In this review it is discussed if acute stress can be fatal. The review is based on literature searches on PubMed, PsycINFO as well as Web of Science. Literature concerning the conditions excited delirium syndrome (ExDS), malignant catatonia, takotsubo cardiomyopathy (TCM), and capture myopathy (CM) is reviewed and compared. Read More

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