487 results match your criteria Cardiology research[Journal]


Echocardiographic Characteristics of Subjects With COVID-19: A Case Series.

Cardiol Res 2020 Aug 3;11(4):260-265. Epub 2020 Jun 3.

Cardiology Department, Hospital Universitario, Universidad Autonoma de Nuevo Leon (UANL), Nuevo Leon, Mexico.

Although coronavirus disease 2019 (COVID-19) manifests in most cases with respiratory symptoms, other presentations can occur. Direct damage to the cardiovascular system has been reported and recently, acute myocardial injury has been identified as a risk factor for mortality. Transthoracic echocardiography is a non-invasive tool that allows the detection of myocardial damage with validated markers (left ventricular ejection fraction and global longitudinal strain). Read More

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http://dx.doi.org/10.14740/cr1084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295558PMC

Single Center Trends in Acute Coronary Syndrome Volume and Outcomes During the COVID-19 Pandemic.

Cardiol Res 2020 Aug 3;11(4):256-259. Epub 2020 Jun 3.

Division of Cardiology, University of California, Los Angeles, CA, USA.

Background: The coronavirus disease 2019 (COVID-19) pandemic has greatly affected healthcare delivery across the world. In this report, we aim to further characterize the changes in cardiac catheterization at our institution, specifically in the setting of acute coronary syndrome (ACS).

Methods: We performed a retrospective analysis of patients undergoing cardiac catheterization between December 23, 2019 and April 12, 2020 at our institution. Read More

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http://dx.doi.org/10.14740/cr1096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295564PMC

Skin Autofluorescence as a Predictor of First Heart Failure Hospitalization in Patients With Heart Failure With Preserved Ejection Fraction.

Cardiol Res 2020 Aug 3;11(4):247-255. Epub 2020 Jun 3.

Hitsumoto Medical Clinic, 2-7-7, Takezakicyou, Shimonoseki City, Yamaguchi 750-0025, Japan. Email:

Background: An autofluorescence (AF) reader can be used to diagnose skin AF non-invasively by measuring local accumulation of advanced glycation end-products. A number of studies have investigated the relationships between skin AF and cardiovascular disease. However, data regarding the usefulness of skin AF as a predictor of chronic heart failure remain limited. Read More

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http://dx.doi.org/10.14740/cr1097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295560PMC

Association of Potentially Inappropriate Medications With All-Cause Mortality in the Elderly Acute Decompensated Heart Failure Patients: Importance of Nonsteroidal Anti-Inflammatory Drug Prescription.

Cardiol Res 2020 Aug 3;11(4):239-246. Epub 2020 Jun 3.

Department of Hospital Pharmaceutics, School of Pharmacy, Showa University, Tokyo, Japan.

Background: Acute decompensated heart failure (ADHF) is the most common cause of readmissions in the hospital. ADHF patients are associated with polypharmacy. It is a common problem among elderly patients due to frequently occurring multiple morbidities and is associated with the use of potentially inappropriate medications (PIMs). Read More

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http://dx.doi.org/10.14740/cr1078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295559PMC

The Determination of the Plaque Burden on the Carotid Artery With Ultrasound Significantly Improves the Risk Prediction in Middle-Aged Subjects Compared to PROCAM: An Outcome Study.

Cardiol Res 2020 Aug 3;11(4):233-238. Epub 2020 Jun 3.

Vascular Risk Foundation (Varifo), Olten, Switzerland.

Background: There are only few data about the predictive value of atherosclerosis imaging beyond traditional risk calculators in younger subjects.

Methods: We assessed cardiovascular risk prediction with the PROCAM (the Prospective Cardiovascular Munster Study) risk equation and with carotid plaque imaging (determination of total plaque area (TPA) and the maximum plaque thickness with ultrasound) in subjects without known cardiovascular diseases. The follow-up was generated during follow-up examinations as part of preventive medical examinations or by telephone calls. Read More

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http://dx.doi.org/10.14740/cr1067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295556PMC

Efficacy of Allopurinol in Cardiovascular Diseases: A Systematic Review and Meta-Analysis.

Cardiol Res 2020 Aug 3;11(4):226-232. Epub 2020 Jun 3.

Thomas Jefferson University, Philadelphia, PA, USA.

Background: Given current evidence, the use of allopurinol for the prevention of major cardiovascular events (acute cardiovascular syndrome (ACS) or cardiovascular mortality) in patients undergoing coronary artery bypass graft (CABG), after index ACS or heart failure remains unknown.

Methods: Multiple databases were queried to identify studies comparing the efficacy of allopurinol in patients undergoing CABG, after ACS or heart failure. The unadjusted odds ratio (OR) was calculated using a random effect model. Read More

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http://dx.doi.org/10.14740/cr1066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295562PMC

Real-World Experience With a Tapered Biodegradable Polymer-Coated Sirolimus-Eluting Stent in Patients With Long Coronary Artery Stenoses.

Cardiol Res 2020 Aug 3;11(4):219-225. Epub 2020 Jun 3.

Department of Cardiology, Ospedale Civile, Cirie, Italy.

Background: Treatment of long coronary stenoses (LCS) with long tapered drug-eluting stents (LT-DES) would offer clinical and economic benefits. However, the feasibility of an interventional strategy based upon the systematic LCS treatment with an LT-DES has not been evaluated so far.

Methods: We performed a multicenter prospective study including consecutive patients with: 1) An LCS > 25 mm at coronary angiography; 2) An attempt to fix the LCS with a single BioMime Morph™ stent, a novel LT-DES available from 30 to 60 mm long. Read More

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http://dx.doi.org/10.14740/cr1055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295557PMC

Upstream Therapy for Atrial Fibrillation Prevention: The Role of Sacubitril/Valsartan.

Cardiol Res 2020 Aug 3;11(4):213-218. Epub 2020 Jun 3.

Department of Cardiology, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.

The therapy or prevention of atrial fibrillation (AF) is defined as upstream therapy when conducted with the use of drugs, e.g., angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor antagonists, statins, and omega-3 fatty acids, not included in the classes of antiarrhythmic drugs recognized by the Vaughan Williams classification. Read More

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http://dx.doi.org/10.14740/cr1073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295563PMC

Causes, Diagnosis, Risk Stratification and Treatment of Bicuspid Aortic Valve Disease: An Updated Review.

Cardiol Res 2020 Aug 3;11(4):205-212. Epub 2020 Jun 3.

Cardiology Department, Nicosia General Hospital, 2029, Nicosia, Cyprus.

The most common congenital heart disease is the bicuspid aortic valve. Understanding the pathophysiology and the altered hemodynamics is a key component for the diagnosis, risk stratification and treatment. Among others, aortic valve stenosis is the most common complication. Read More

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http://dx.doi.org/10.14740/cr1061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295561PMC

A Precipitous Decision: Transcatheter Aortic Valve Replacement in Low-Risk Patients.

Cardiol Res 2020 Jun 3;11(3):200-203. Epub 2020 May 3.

Division of Cardiology, Pittsburgh V.A. Medical Center, University of Pittsburgh, Pittsburgh, PA 15260, USA. Email:

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http://dx.doi.org/10.14740/cr1062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239588PMC

Coronavirus Disease 2019 With Acute Respiratory Distress Syndrome Mimicking Heart Failure Exacerbation: Time to Rethink.

Cardiol Res 2020 Jun 3;11(3):196-199. Epub 2020 May 3.

Detroit Heart Center, Wayne State University, Detroit, MI, USA.

A 67-year-old man with a prior heart failure presented with fever, cough and dyspnea for 4 days. Physical examination showed bilateral rales on the lung exam, yet no lower extremity edema. The combination of symptoms, elevated inflammatory markers, normal baseline pro-B-type natriuretic peptide, PaO/FiO < 300 and positive swab suggested coronavirus disease 2019 (COVID-19) with acute respiratory distress syndrome (ARDS) rather than heart failure exacerbation. Read More

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http://dx.doi.org/10.14740/cr1074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239589PMC

Aggressive Endocarditis in a Young Healthy Patient: A Case Report.

Cardiol Res 2020 Jun 3;11(3):192-195. Epub 2020 May 3.

Department of Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ 07753, USA.

() is a β-hemolytic coagulase-negative staphylococcus causing skin and soft tissue infections with an increasing incidence. Commonly found as normal flora in the perineal region, has been found in rare cases of infective endocarditis causing increased morbidity and mortality. We present a case of a previously healthy young male diagnosed with -caused infective endocarditis. Read More

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http://dx.doi.org/10.14740/cr1037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239590PMC

T-Peak to T-End Improvements After Beta-Blocker Administration in Peripartum Cardiomyopathy Patients.

Cardiol Res 2020 Jun 3;11(3):185-191. Epub 2020 May 3.

Cardiology and Vascular Medicine Department, Hasan Sadikin General Hospital, Universitas Padjadjaran, Bandung, Indonesia.

Background: Many studies have shown that T-peak to T-end (TPTE) interval was associated with sudden cardiac events. Peripartum cardiomyopathy (PPCM) causes reversible left ventricle systolic dysfunction which may deteriorate into sudden cardiac death. This study aimed to evaluate beta-blocker as an antiarrhythmic agent to improve TPTE interval as a prognostic value of sudden cardiac death. Read More

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http://dx.doi.org/10.14740/cr1053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239595PMC

Is the Time of Atrial Fibrillation Recurrence After Duty-Cycled Radiofrequency Ablation Affected by the Pattern of Pulmonary Vein Reconnections?

Cardiol Res 2020 Jun 3;11(3):179-184. Epub 2020 May 3.

Department of Cardiology and Electrophysiology, St. Agnes-Hospital Bocholt, Barloer Weg 125, Bocholt 46397, Germany.

Background: Pulmonary vein isolation (PVI) with multielectrode duty-cycled radiofrequency (PVAC) has been shown to be effective in the treatment of atrial fibrillation (AF). We describe pulmonary vein (PV) reconnection at repeat ablation in patients with AF recurrence after PVAC PVI and analyze the correlation between the time of AF recurrence and the observed PV reconnection patterns.

Methods: Eighty-five patients undergoing a redo PVI for recurrent AF 9. Read More

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http://dx.doi.org/10.14740/cr1050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239587PMC

Comparing Transcatheter Aortic Valve Replacement (AVR) With Surgical AVR in Lower Risk Patients: A Comprehensive Meta-Analysis and Systematic Review.

Cardiol Res 2020 Jun 3;11(3):168-178. Epub 2020 May 3.

Department of Cardiology, Mercy Saint Vincent Medical Center, Toledo, OH 43608, USA.

Background: Transcutaneous aortic valve replacement (TAVR) is a novel percutaneous procedure for severe aortic stenosis and has been recently approved by Food and Drug Administration in lower risk patients. We performed the first ever meta-analysis and literature review of clinical trials comparing both 30-day and 1-year outcomes in lower risk patients undergoing TAVR vs. surgical aortic valve replacement (SAVR, having Society of Thoracic Surgeons score < 4% or equivalent). Read More

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http://dx.doi.org/10.14740/cr1046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239597PMC

Aortic Valve Calcification as a Predictor of Post-Transcatheter Aortic Valve Replacement Pacemaker Dependence.

Cardiol Res 2020 Jun 3;11(3):155-167. Epub 2020 May 3.

Department of Medicine, The Warren Alpert Medical School of Brown University, Providence, RI, USA.

Background: Atrioventricular block requiring permanent pacemaker (PPM) implantation is a common complication of transcatheter aortic valve replacement (TAVR). The mechanism of atrioventricular (AV) block during TAVR is not fully understood, but it may be due to the mechanical stress of TAVR deployment, resulting in possible injury to the nearby compact AV node. Aortic valve calcification (AVC) may worsen this condition and has been associated with an increased risk for post-TAVR PPM implantation. Read More

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http://dx.doi.org/10.14740/cr1011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239596PMC

Diagnostic Accuracy of Cardiac Magnetic Resonance Versus Fractional Flow Reserve: A Systematic Review and Meta-Analysis.

Cardiol Res 2020 Jun 3;11(3):145-154. Epub 2020 May 3.

St. Mary Medical Center, Langhorne, PA, USA.

Background: Fractional flow reserve (FFR) is considered the gold standard for diagnosis of coronary artery disease (CAD). Stress Cardiac magnetic resonance (SCMR) has been recently gaining traction as a non-invasive alternative to FFR.

Methods: Studies comparing the diagnostic accuracy of SCMR versus FFR were identified and analyzed using Review Manager (RevMan) 5. Read More

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http://dx.doi.org/10.14740/cr1028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239594PMC

What is New in Pharmacologic Therapy for Cardiac Resuscitation?

Cardiol Res 2020 Jun 3;11(3):141-144. Epub 2020 May 3.

Roslyn Franklin University of Health Sciences, Chicago, IL, USA.

Antiarrhythmic therapy can be a critical component of cardiac resuscitation. Therapies in this area have seen little advance in the last decade. Bretylium, a very old drug, has been reintroduced for ventricular tachycardia/ventricular fibrillation (VT/VF) therapy. Read More

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http://dx.doi.org/10.14740/cr1058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239592PMC

Frontiers in Cardiology Research.

Authors:
John Somberg

Cardiol Res 2020 Jun 3;11(3):140. Epub 2020 May 3.

Cardiology & Pharmacology, Rush University, Chicago, IL 60612, USA. Email:

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http://dx.doi.org/10.14740/cr1057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239591PMC

Let Us Aggressively Confront the Coronavirus Pandemic.

Authors:
John Somberg

Cardiol Res 2020 Jun 3;11(3):139. Epub 2020 May 3.

Cardiology & Pharmacology, Rush University, Chicago, IL 60612, USA. Email:

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http://dx.doi.org/10.14740/cr1065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239593PMC

Peripheral Embolization of Left Ventricular Thrombus Leading to Acute Bilateral Critical Limb Ischemia: A Rare Phenomenon.

Cardiol Res 2020 Apr 10;11(2):134-137. Epub 2020 Mar 10.

Department of Cardiology, Jersey Shore University Medical Center, Neptune, NJ 07753, USA.

Left ventricular thrombus (LVT) is a well-known complication of myocardial infarction (MI) leading to significant morbidity and mortality. LVT can also lead to systemic thromboembolic events causing threatening limb ischemia. We report a rare case of critical bilateral limb ischemia that resulted from peripheral embolization of LVT post MI, which was managed successfully by emergent surgical intervention and anticoagulation. Read More

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http://dx.doi.org/10.14740/cr1030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092770PMC

Primary Cardiac Undifferentiated High-Grade Intimal Pleomorphic Sarcoma: A Case Series Report.

Cardiol Res 2020 Apr 10;11(2):129-133. Epub 2020 Mar 10.

Division of Cardiology, Atlantic Health System, Overlook Medical Center, 99 Beauvoir Ave, Summit, NJ 07901, USA.

We report two patients with primary cardiac sarcomas. The first patient was admitted for dyspnea on exertion secondary to congestive heart failure. She was later diagnosed with intimal pleomorphic sarcoma involving the right ventricular outflow tract extending into the pulmonary artery, which was further complicated by metastasis to the lung. Read More

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http://dx.doi.org/10.14740/cr1029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092767PMC

Erdheim-Chester Disease With Extensive Pericardial Involvement: A Case Report and Systematic Review.

Cardiol Res 2020 Apr 10;11(2):118-128. Epub 2020 Mar 10.

Department of Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL, USA.

Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis characterized by systemic xanthogranulomatous infiltration. We described the case of a female adult presenting with pericardial effusion. Pericardial infiltration is the most frequent cardiac manifestation of ECD and is the one discussed in this article. Read More

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http://dx.doi.org/10.14740/cr1025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092773PMC

Early Structural Deterioration of a Sutureless Bioprosthetic Aortic Valve.

Cardiol Res 2020 Apr 10;11(2):113-117. Epub 2020 Mar 10.

Division of Cardiology, Department of Medicine, Staten Island University Hospital, Staten Island, NY, USA.

Sutureless bioprosthetic valves such as the Sorin Perceval S valve (SPV) have been used in patients with aortic stenosis that require surgical aortic valve replacement (SAVR). These prostheses have been marketed on the basis of their rapid implantation techniques with avoidance of sutures and reduced aortic cross-clamp times. We report a case of an early failure of a SPV nearly 4 years after implantation in a 58-year-old woman who was low-risk. Read More

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http://dx.doi.org/10.14740/cr1013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092772PMC

Correlation Between the Cardio-Ankle Vascular Index and Renal Resistive Index in Patients With Essential Hypertension.

Cardiol Res 2020 Apr 10;11(2):106-112. Epub 2020 Mar 10.

Hitsumoto Medical Clinic, 2-7-7, Takezakicyou, Shimonoseki City, Yamaguchi 750-0025, Japan. Email:

Background: Renal resistive index (RRI) is a parameter determined by Doppler sonography that reflects renal hemodynamics. Significant relationships connecting increases in the RRI with cardiovascular risk factors and the incidence of cardiovascular disease in hypertensive patients have been reported. This cross-sectional study aimed to clarify the relationship between cardio-ankle vascular index (CAVI), a novel marker of arterial stiffness, and the RRI in patients with essential hypertension with the goal of primary prevention of cardiovascular disease. Read More

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http://dx.doi.org/10.14740/cr1026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092774PMC

Characterization of Sedentary Behavior in Heart Failure Patients With Arthritis.

Cardiol Res 2020 Apr 10;11(2):97-105. Epub 2020 Mar 10.

College of Nursing, Augusta University, Augusta, GA, USA.

Background: Arthritis is one of the most common comorbidities in heart failure (HF) patients, and is associated with decreased activity levels. Few studies have examined sedentary behavior (SB) in HF patients with arthritis, and little is known about the factors that may influence SB in this population.

Methods: This is a retrospective, secondary analysis using data collected from a randomized control trial. Read More

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http://dx.doi.org/10.14740/cr1023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092775PMC

Stress Echocardiography: Concept and Criteria, Structure and Steps, Obstacles and Outcomes, Focused Update and Review.

Cardiol Res 2020 Apr 10;11(2):89-96. Epub 2020 Mar 10.

Cardiology Division, Echocardiology Unit, University Hospital Notre Dame des Secours, PO Box 3, Byblos, Lebanon.

Stress echocardiography (SEC) is a technique established more than 35 years ago; however, it is still poorly implemented in many countries and institutions, and this reluctance may be related to many obstacles such as operator skills, lack of awareness or institutional policy. Stress echo was initially used for assessing coronary artery disease (CAD), with respect to myocardial viability, using wall motion response; however, current use of stress echo extends beyond CAD, such as valvular heart disease and diastolic stress test. Dobutamine is a commonly used agent when pharmaceutical approach is implemented. Read More

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http://dx.doi.org/10.14740/cr851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092766PMC

An Update on the Pathophysiology and Treatment of Cardiorenal Syndrome.

Cardiol Res 2020 Apr 10;11(2):76-88. Epub 2020 Mar 10.

Department of Cardiology, Summa Health, Akron, OH, USA.

Cardiorenal syndrome (CRS) encompasses various disorders of the heart and kidneys; dysfunction of one organ leads to acute or chronic dysfunction of the other. It incorporates the intersection of heart-kidney interactions across several mediums, hemodynamically, through the alterations in neurohormonal markers, and increased venous and renal pressure, all of which are hallmarks of its clinical phenotypes. This article explores the epidemiology, pathology, classification and treatment of each type of CRS. Read More

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http://dx.doi.org/10.14740/cr955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092771PMC

Thyroid and Cardiovascular Disease: A Focused Review on the Impact of Hyperthyroidism in Heart Failure.

Cardiol Res 2020 Apr 10;11(2):68-75. Epub 2020 Mar 10.

Department of Cardiology, University of Tennessee at Chattanooga, 975 E 3rd Street, Chattanooga, TN 37403, USA.

The association between thyroid hormones and cardiovascular conditions has been well studied, specifically, the effects of hypothyroidism on cardiomyopathy, and hyperthyroidism with arrhythmias. Nonetheless, an explicit correlation between hyperthyroidism and cardiomyopathy has yet to be established. Medical databases MEDLINE and PubMed were accessed and queried as primary sources for data acquisition. Read More

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http://dx.doi.org/10.14740/cr1034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092768PMC

Let Us Do Not Forget Durability.

Authors:
John Somberg

Cardiol Res 2020 Apr 10;11(2):67. Epub 2020 Mar 10.

Cardiology & Pharmacology, Rush University, Chicago, IL 60612, USA. Email:

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http://dx.doi.org/10.14740/cr1039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092769PMC

Ventricular Tachycardia in an Infant Without Congenital Anomaly: A Case Report.

Cardiol Res 2020 Feb 26;11(1):61-65. Epub 2020 Jan 26.

Pediatric Cardiology Department, Hotel-Dieu de France University Hospital, Saint Joseph University, Medical School, Alfred Naccache Boulevard, Achrafieh, Beirut,Lebanon.

Ventricular tachycardia (VT) is a serious form of arrhythmia that can be life-threatening; that's why diagnosis and treatment are very important in order to avoid serious complications. We are reporting this case of VT which is a rare entity, especially, in healthy infants. This infant, without cardiac pathology known from birth, presented with poor food intake and grunting with hepatomegaly on clinical examination, and a heartbeat at 200/ min. Read More

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http://dx.doi.org/10.14740/cr1005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011923PMC
February 2020

Incidence of Atrioventricular Block After Valve Replacement in Carcinoid Heart Disease.

Cardiol Res 2020 Feb 26;11(1):56-60. Epub 2020 Jan 26.

Division of Cardiovascular Sciences, University of South Florida Morsani College of Medicine, Tampa, FL 33606, USA.

Background: Carcinoid heart disease (CaHD) is a rare condition that has a high impact on the morbidity and mortality of its patients. Once heart failure symptoms develop in the patient with CaHD, cardiac valve surgery is often the only effective treatment. Although atrioventricular block (AVB) is a known postoperative complication of the valve surgery, the incidence of AVB in this population has not been well described. Read More

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http://dx.doi.org/10.14740/cr986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011921PMC
February 2020

Is Lipoprotein (a) a Risk Factor for Coronary Artery Ectasia?

Cardiol Res 2020 Feb 26;11(1):50-55. Epub 2020 Jan 26.

Cardiology Department, University of Jordan, Amman, Jordan.

Background: The pathophysiology of coronary artery ectasia (CAE) is under investigated and not well understood. Atherosclerosis is considered as the main etiologic factor for CAE in adults where more than 50% of CAE patients have atherosclerosis. Recently, lipoprotein (a) (Lp(a)) has emerged as a powerful risk factor for atherosclerosis and coronary artery disease (CAD). Read More

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http://dx.doi.org/10.14740/cr992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011929PMC
February 2020

Effect of Ivabradine on Left Ventricular Diastolic Function, Exercise Tolerance and Quality of Life in Patients With Heart Failure: A Systemic Review and Meta-Analysis of Randomized Controlled Trials.

Cardiol Res 2020 Feb 26;11(1):40-49. Epub 2020 Jan 26.

Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, China.

Background: Ivabradine is a heart rate-lowering drug that selectively inhibits the funny (I) current of the sinoatrial node. It is currently recommended in patients with heart failure (HF) with reduced ejection fraction (HFrEF) in sinus rhythm and a heart rate of ≥ 70 beats per minute (bpm) at rest. To investigate whether ivabradine has an effect on diastolic dysfunction, exercise tolerance and quality of life (QOL), we conducted a systemic review and meta-analysis of randomized controlled trials (RCTs). Read More

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http://dx.doi.org/10.14740/cr958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011928PMC
February 2020

Preliminary Observations on the Antihypertension Action of Dabigatran Etexilate in Patients With Nonvalvular Atrial Fibrillation: A Prospective Multicenter Single-Arm Interventional Study.

Cardiol Res 2020 Feb 26;11(1):33-39. Epub 2020 Jan 26.

Department of Cardiovascular Diseases, Fukuoka University Chikushi Hospital, 1-1-1 Zokumyouin, Chikushino, Fukuoka 818-8502, Japan.

Background: In Japan, the number of patients with atrial fibrillation continues to grow with the aging of the population. Prevention of cardiogenic cerebral embolism is extremely important in patients with atrial fibrillation. While warfarin has long played a major role for this purpose, a new oral anticoagulant, dabigatran etexilate (dabigatran), has demonstrated superior efficacy and safety in recent years. Read More

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http://dx.doi.org/10.14740/cr1007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011926PMC
February 2020

Paroxysmal Atrial Fibrillation: Insight Into the Intimate Mechanisms of Coagulation.

Cardiol Res 2020 Feb 26;11(1):22-32. Epub 2020 Jan 26.

Department of Cardiology, Medical University of Varna, Varna, Bulgaria.

Background: Atrial fibrillation (AF) is a hypercoagulable state. However, the intimate mechanisms leading to impaired coagulation and the timing of their activation are unclear. The aim of the study was to investigate the factors that initiate the coagulation cascade in the early hours (up to 48 h) of clinical manifestation of paroxysmal atrial fibrillation (PAF). Read More

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http://dx.doi.org/10.14740/cr972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011925PMC
February 2020

Polypharmacy Is Associated With Accelerated Deterioration of Renal Function in Cardiovascular Outpatients.

Cardiol Res 2020 Feb 26;11(1):15-21. Epub 2020 Jan 26.

Graduate School of Pharmacy, Hyogo University of Health Sciences, Kobe, Japan.

Background: Polypharmacy is associated with poor prognosis of patients with various diseases. However, it has not been precisely addressed how polypharmacy affects the clinical characteristics of the cardiovascular outpatients. The aim of this study is to search for the clinical characteristics related to the number of prescribed drugs in the cardiovascular outpatients. Read More

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http://dx.doi.org/10.14740/cr991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011922PMC
February 2020

Kawasaki Disease: Global Burden and Genetic Background.

Cardiol Res 2020 Feb 26;11(1):9-14. Epub 2020 Jan 26.

Cardiovascular Department, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China.

Kawasaki disease (KD) is a childhood vasculitides associated with serious coronary artery lesions. It is the most common cause of pediatric acquired heart disease in developed countries, and is increasingly reported from many rapidly industrializing developing countries. The incidence varies widely among different nations and is highest in North-East Asian countries, where almost 1 in 100 children in Japan having the disease by age of 5, where the lowest incidence reported in sub-Saharan Africa. Read More

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http://dx.doi.org/10.14740/cr993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011927PMC
February 2020

Indications of Cardiac Resynchronization in Non-Left Bundle Branch Block: Clinical Review of Available Evidence.

Cardiol Res 2020 Feb 26;11(1):1-8. Epub 2020 Jan 26.

Cardiology Department, Heart and Vascular Center, Mater Private Hospital, Dublin 7, Ireland.

Cardiac resynchronization therapy (CRT) benefits have been firmly established in patients with heart failure and reduced left ventricular ejection fraction (HFrEF), who remain in New York Heart Association (NYHA) functional classes II and III, despite optimal medical therapy, and have a wide QRS complex. An important and consistent finding in published systematic reviews and in subgroup analyses is that the benefits of CRT are maximum for patients with a broader QRS durations, typically described as QRS duration > 150 ms, and for patients with a typical left bundle branch block (LBBB) QRS morphology. It remains uncertain whether patients with non-LBBB QRS complex morphology clearly benefit from CRT or only modestly respond. Read More

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http://dx.doi.org/10.14740/cr989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011924PMC
February 2020

Left Atrial Tumor Thrombus in a Patient With Squamous Cell Carcinoma of Lung.

Cardiol Res 2019 Dec 24;10(6):382-387. Epub 2019 Nov 24.

Division of Cardiovascular Medicine, Mountain Home VA Medical Center, Lamont Street and Veterans Way, Johnson City, TN 37604, USA.

Tumor thrombus in left atrium (LA) is very rare but a serious complication in patients with malignancy. It has a significant impact on clinical decision making, staging and prognosis in oncological patients. Tumor thrombus is seen in a wide variety of malignancies. Read More

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http://dx.doi.org/10.14740/cr943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879046PMC
December 2019

Aortic Valve Papillary Fibroelastoma: A Sea Anemone in the Heart, A Case Report.

Cardiol Res 2019 Dec 24;10(6):378-381. Epub 2019 Nov 24.

Department of Internal Medicine, University of Nevada - Reno, School of Medicine, Reno, NV, USA.

Cardiac papillary fibroelastomas are benign primary cardiac tumors usually arising from the normal components of the endocardium. Grossly they have a characteristic short pedicle and multiple papillary fronds similar to sea anemone. Clinically they have varying presentations ranging from asymptomatic to severe ischemic or embolic complications. Read More

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http://dx.doi.org/10.14740/cr818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879048PMC
December 2019

Pre-Operative Sildenafil for Patients With Pulmonary Hypertension Undergoing Mitral Valve Surgery: A Systematic Review and Meta-Analysis.

Cardiol Res 2019 Dec 24;10(6):369-377. Epub 2019 Nov 24.

Division of Cardiovascular Medicine, University of the Philippines, Philippine General Hospital, Manila 1000, Philippines.

Background: Pulmonary hypertension is a usual complication of long-standing mitral valve disease. Perioperative pulmonary hypertension is a risk factor for right ventricular failure and is an important cause of morbidity and mortality in patients with pulmonary hypertension undergoing mitral valve surgery. Phosphodiesterase-5 inhibitors particularly sildenafil citrate have proven clinical benefit for pulmonary arterial hypertension but have shown discordant results in group 2 pulmonary hypertension patients. Read More

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http://dx.doi.org/10.14740/cr962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879044PMC
December 2019

Incidence, Characteristics and Atherosclerotic Involvement of Coronary Artery Anomalies in Adult Population Undergoing Catheter Coronary Angiography.

Cardiol Res 2019 Dec 24;10(6):358-368. Epub 2019 Nov 24.

Department of Medicine, GGS Medical College and Hospital, Faridkot, Punjab, India.

Background: Coronary artery anomalies (CAAs) are rare disorders of coronary anatomy with varied clinical presentations. There are widespread geographic variations in incidence and patterns of these anomalies, with limited data from North Indian population. We performed a retrospective study to evaluate the incidence, characteristics and atherosclerotic involvement of CAAs in adult population undergoing catheter coronary angiography. Read More

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http://dx.doi.org/10.14740/cr941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879043PMC
December 2019

Practical Risk Stratification Score for Prediction of Contrast-Induced Nephropathy After Primary Percutaneous Coronary Intervention in Patients With Acute ST-Segment Elevation Myocardial Infarction.

Cardiol Res 2019 Dec 24;10(6):350-357. Epub 2019 Nov 24.

Center for Clinical Epidemiology and Clinical Statistics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Background: Contrast-induced nephropathy (CIN) is a common complication of percutaneous coronary intervention (PCI). This study aimed to develop a new risk stratification score that is simpler and more practical than the standard Mehran risk score (MRS) in prediction of CIN after primary PCI in ST-segment elevation myocardial infarction (STEMI) patients.

Methods: A prognostic prediction research with clinical risk score development was conducted. Read More

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http://dx.doi.org/10.14740/cr939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879045PMC
December 2019

Short-Term Clinical Follow-Up After Thrombolytic Therapy in Patients With Prosthetic Valve Thrombosis: A Single-Center Experience.

Cardiol Res 2019 Dec 24;10(6):345-349. Epub 2019 Nov 24.

Department of Cardiology, King George's Medical University, Shah Mina Road, Lucknow, Uttar Pradesh 226003, India.

Background: Thrombolytic therapy has evolved as an alternative to surgery for prosthetic valve thrombosis (PVT). Therefore, this retrospective, single-center study aimed to evaluate the clinical profile of PVT and the role of thrombolytic therapy in patients with PVT.

Methods: Data from a total of 16 consecutive patients with PVT enrolled between January 2017 and January 2018 at a tertiary care center in India were retrospectively evaluated. Read More

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http://dx.doi.org/10.14740/cr924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879042PMC
December 2019

The Safety and Efficacy of Guidezilla Catheter (Mother-in-Child Catheter) in Complex Coronary Interventions: An Observational Study.

Cardiol Res 2019 Dec 24;10(6):336-344. Epub 2019 Nov 24.

Department of Cardiology, LPS Institute of Cardiology, G.S.V.M. Medical College, Kanpur, Uttar Pradesh, India.

Background: Lesion characteristics (anatomy, calcification, tortuosity and angulation), vessel morphology, and lack of support add complexity of coronary intervention. Guidezilla catheter, acting as an extension of guide catheter system (mother-in-child catheter), helps to overcome these complexities by enhancing backup during complex intervention.

Methods: The present retrospective, single-center study included 13,157 consecutive patients who underwent percutaneous coronary intervention (PCI) through both transfemoral and transradial routes from January 2015 to July 2019 at LPS Institute of Cardiology, G. Read More

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http://dx.doi.org/10.14740/cr949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879049PMC
December 2019

Expedited Removal of a Radial Hemostatic Compression Device Following Cardiac Catheterization Is Safe and Associated With Reduced Time to Discharge.

Cardiol Res 2019 Dec 24;10(6):331-335. Epub 2019 Nov 24.

Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

Background: Radial access for cardiac catheterization has become increasingly adopted, owing much of its popularity to decreased bleeding complications compared with the femoral approach. Hemostatic compression devices (HCDs) for radial catheterization play a key role in this advantage, but the optimal duration of compression is unknown. A shorter duration of compression is encouraged by guidelines, but removing an HCD too quickly could result in serious bleeding. Read More

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http://dx.doi.org/10.14740/cr953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879050PMC
December 2019

Risk Stratification for Transcatheter Aortic Valve Replacement.

Cardiol Res 2019 Dec 24;10(6):323-330. Epub 2019 Nov 24.

Division of Cardiovascular Medicine, East Tennessee State University, Johnson City, TN, USA.

Risk assessment models developed from administrative and clinical databases are used for clinical decision making. Since these models are derived from a database, they have an inherent limitation of being as good as the data they are derived from. Many of these models under or overestimate certain clinical outcomes particularly mortality in certain group of patients. Read More

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http://dx.doi.org/10.14740/cr966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879047PMC
December 2019

Endocarditis Presenting With Septic Shock in an Immunocompetent Female Patient.

Cardiol Res 2019 Oct 4;10(5):318-322. Epub 2019 Oct 4.

Division of Infectious Diseases, Department of Internal Medicine, School of Medicine, University of Patras, 26504, Rion-Patras, Greece.

() is a rare cause of infective endocarditis, despite being a common cause of bacteremia. endocarditis affects most frequently immunocompromised elderly women, especially those with diabetes mellitus. We present a case of a 78-year-old female immunocompetent patient, presenting with septic shock and multiple organ dysfunction syndrome. Read More

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http://dx.doi.org/10.14740/cr940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785298PMC
October 2019
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Very Early Coronary Artery Aneurysm After Primary Percutaneous Coronary Intervention in Patient With HIV and Thrombophilia.

Cardiol Res 2019 Oct 4;10(5):312-317. Epub 2019 Oct 4.

University of Pernambuco, UPE, Recife, Brazil.

The incidence of coronary artery aneurysms ranges from 0.2% to 10.5%. Read More

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http://dx.doi.org/10.14740/cr907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785299PMC
October 2019