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    1372 results match your criteria Cardiology journal[Journal]

    1 OF 28

    Implantation of bioresorbable scaffolds under guidance of optical coherence tomography: feasibility and pilot clinical results of a systematic protocol.
    Cardiol J 2018 May 18. Epub 2018 May 18.
    Klinikum Frankfurt (Oder), Interventional Cardiology, Germany, Frankfurt/O, Germany; Institute of Cardiovascular Translation Research of the Atlantic (ICTRA), Berlin, Germany.
    Background: We hypothesise that a comprehensive optical coherence tomography (OCT)-guided implantation protocol for bioresorbable scaffolds (BRS) might improve expansion and apposition, thus translating into better clinical outcomes, particularly reducing thrombotic events.

    Methods: Patients considered suitable for BRS therapy in de novo coronary lesions underwent OCT. The predominant type of plaque was classified as lipidic, fibrous or calcific, undergoing tailored plaque preparation accordingly. Read More

    Mechanical efficiency of high versus moderate intensity aerobic exercise in coronary heart disease patients: A randomized clinical trial.
    Cardiol J 2018 May 10. Epub 2018 May 10.
    Infanta Elena University Hospital, Avda. Reyes Católicos 21, 28340 Valdemoro, Spain.
    Background: Mechanical efficiency (ME) refers to the ability of an individual to transfer energy consumed by external work. A decreased ME, could represent an increased energy cost during exercise and may, therefore, be limited in terms of physical activity. This study aimed to compare the influence of two different exercise protocols: moderate continuous training (MCT) versus high intensity interval training (HIIT), as part of a cardiac rehabilitation program on ME values among coronary patients. Read More

    Comparison of short-term clinical outcomes between Resolute Onyx zotarolimus-eluting stents and everolimus-eluting stent in patients with acute myocardial infarction: Results from the Korea Acute Myocardial infarction Registry (KAMIR).
    Cardiol J 2018 May 10. Epub 2018 May 10.
    Chonnam National University Hospital, 671 Jaebongro, Dong-gu, 61469 Gwangju, Korea, Republic Of.
    Background: There are few studies which compare the efficacy and safety of the Resolute Onyx zotarolimus-eluting stent (O-ZES) and everolimus-eluting stent (EES) in patients with acute myocardial infarction (AMI). Therefore, the present study aimed to compare clinical outcomes of O-ZES and EES in patients with AMI undergoing successful percutaneous coronary intervention (PCI).

    Methods: From January 2016 to December 2016, the Korea Acute Myocardial Infarction Registry (KAMIR) enrolled 3,364 consecutive patients. Read More

    The long noncoding RNA THRIL knockdown protects hypoxia-induced injuries of H9C2 cells through regulating miR-99a.
    Cardiol J 2018 May 10. Epub 2018 May 10.
    Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine.
    Background: Myocardial infarction (MI) is a leading cause of disease with high morbidity and mortality worldwide. Recent studies have revealed that long non-coding RNAs (lncRNAs) are involved in heart disease pathogenesis. This study aimed to investigate the effect and the molecular basis of THRIL on hypoxia-injured H9C2 cells. Read More

    Monotherapy of aspirin or warfarin for prevention of ischemic stroke in low-risk atrial fibrillation: A Easter Asian population-based study.
    Cardiol J 2018 May 2. Epub 2018 May 2.
    National Taipei University of Nursing and Health Sciences, Taiwan, Province of China.
    Background: This study aimed to investigate the effectiveness of monotherapy aspirin and warfarin for stroke prevention in low-risk atrial fibrillation (AF) by using a population-based cohort study in Taiwan.

    Methods: A newly diagnosed low-risk AF patient cohort were identified by using National Health Insurance Research Database (NHIRD) in Taiwan in 2008. The study cohort was observed with a follow-up of 2 years to examine the onset of ischemic stroke (IS) (to 2010). Read More

    The subcutaneous implantable cardioverter-defibrillator: A tertiary center experience.
    Cardiol J 2018 May 2. Epub 2018 May 2.
    Department of Medical Sciences Uppsala University, 751 85, Uppsala, Sweden.
    Background: The aim of the study was to evaluate subcutaneous implantable cardioverter-defibrillator (S-ICD) patients with regard to underlying etiology, peri-procedural outcome, appropriate/inappropriate shocks, and complications during follow-up.

    Methods: All patients who underwent S-ICD implantation from February 2013 to March 2017 at an academic hospital in Vienna were included. Medical records were examined and follow-up interrogations of devices were conducted. Read More

    Loss of AMIGO2 causes dramatic damage to cardiac preservation after ischemic injury.
    Cardiol J 2018 May 2. Epub 2018 May 2.
    Xixi Hospital of Hangzhou, Hengbu Street 2, Xihu District, Hangzhou, Zhejiang, China, 310023 Hangzhou, China.
    Background: Recent studies have identified amphoterin-induced gene and open reading frame (AMIGO) 2. The role of AMIGO2 in tumour research is well-studied, but its role in ischemic heart diseases is seldom reported. In the present study, the role of AMIGO2 in myocardial infarction is under investigation for the first time. Read More

    Effect of LCZ696, a dual angiotensin receptor neprilysin inhibitor, on isoproterenol-induced cardiac hypertrophy, fibrosis, and hemodynamic change in rats.
    Cardiol J 2018 May 2. Epub 2018 May 2.
    Okayama University.
    Background: Recent clinical studies have shown that treatment with LCZ696, a complex containing the angiotensin receptor blocker valsartan and neprilysin inhibitor sacubitril, improves the prognosis of heart failure patients with a reduced ejection fraction. This study evaluated whether LCZ696 affects left ventricular hypertrophy, fibrosis, and hemodynamics in isoproterenol (ISO)-treated rats compared with valsartan alone.

    Methods: Male Wistar rats received subcutaneous saline (n = 10), subcutaneous ISO (2. Read More

    Impact of left atrial appendage closure on cardiac functional and structural remodeling: A Difference-in-Difference analysis of propensity score matched samples.
    Cardiol J 2018 May 2. Epub 2018 May 2.
    Chung-Ang University Hospital, 102 Heukseok ro, Dongjak gu, 06548 Seoul, Korea, Republic Of; Quang Nam Central General Hospital, 01 Pham Van Dong, Nui Thanh, Quang Nam, Vietnam, 562314 Quang Nam, Viet Nam.
    Background: Although the safety and efficacy of left atrial appendage (LAA) closure (LAAC) in nonvalvular atrial fibrillation (NVAF) patients have been well documented in randomized controlled trials and real-world experience, there are limited data in the literature about the impact of LAAC on cardiac remodeling. The aim of the study was to examine the impact of LAAC on cardiac functional and structural remodeling in NVAF patients.

    Method: s: Between March 2014 and November 2016, 47 NVAF patients who underwent LAAC were included in this study (LAAC group). Read More

    Established and potential echocardiographic markers of embolism and their therapeutic implications in patients with ischemic stroke.
    Cardiol J 2018 May 2. Epub 2018 May 2.
    Department of Neurology and Ischemic Strokes, Medical University of Lodz, Zeromskiego 113, 90- 549 Lodz, Poland.
    Cardiogenic strokes comprised 11% of all strokes and 25% of ischemic strokes. An accurate identification of the cause of stroke is necessary in order to prepare an adequate preventive strategy. In this review the confirmed and potential causes of embolic strokes are presented, which can be detected in echocardiography in the context of present treatment guidelines and gaps in evidence. Read More

    Treatment of patients with acute coronary syndrome: Recommendations for medical emergency teams: Focus on antiplatelet therapies. Updated experts' standpoint.
    Cardiol J 2018 Apr 19. Epub 2018 Apr 19.
    Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
    A group of Polish experts in cardiology and emergency medicine, encouraged by the European Society of Cardiology (ESC) guidelines, have recently published common recommendations for medical emergency teams regarding the pre-hospital management of patients with acute coronary syndrome. Due to the recent publication of the 2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation and 2017 focused update on dual antiplatelet therapy in coronary artery disease the current panel of experts decided to update the previous standpoint. Moreover, new data coming from studies presented after the previous document was issued were also taken into consideration. Read More

    Trends in hypertension prevalence, awareness, treatment and control among Polish adults 75 years and older during 2007-2014.
    Cardiol J 2018 Apr 19. Epub 2018 Apr 19.
    Department of Hypertension, Angiology and Internal Disease, Poznan University of Medical Science, ul.Dluga 1/2, 61-848 Poznan, Poland.
    Background: The aim of this study was to assess changes in the prevalence, awareness and treatment of hypertension and its effectiveness between 2007 (WOBASZ Senior study) and 2013-2014 (WOBASZ II) in a sample of the Polish population over the age of 75 years.

    Methods: Sampling had three stages, stratified according to voivodeships, type of community, and gender. Finally, the WOBASZ II study included 467 persons (290 women and 177 men). Read More

    Predictors of periprocedural complications in patients undergoing percutaneous coronary interventions within coronary bypass grafts.
    Cardiol J 2018 Apr 19. Epub 2018 Apr 19.
    2nd Department of Cardiology, Jagiellonian University Medical College, Krakow, Poland.
    Background: During the first decade following the coronary bypass grafting, at least 10 of the patients require percutaneous coronary interventions (PCI) due to graft failure. Saphenous vein grafts (SVG) are innately at a higher risk of periprocedural complications. The present study aimed to investigate predictors of periprocedural complications of PCI within coronary artery bypass grafts. Read More

    P2Y12 antagonist ticagrelor inhibits the release of procoagulant extracellular vesicles from activated platelets: Preliminary results.
    Cardiol J 2018 Apr 19. Epub 2018 Apr 19.
    1st Chair and Department of Cardiology, Medical University of Warsaw, Warsaw, Poland; Vesicle Observation Centre, and Laboratory of Experimental Clinical Chemistry, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands.
    Background: Activated platelets release platelet extracellular vesicles (PEVs). Adenosine diphosphate (ADP) receptors P2Y1 and P2Y12 both play a role in platelet activation, The present hypothesis herein is that the inhibition of these receptors may affect the release of PEVs.

    Methods: Platelet-rich plasma from 10 healthy subjects was incubated with saline, P2Y1 antagonist MRS2179 (100 µM), P2Y12 antagonist ticagrelor (1 µM), and a combination of both antagonists. Read More

    Initial experience with the subcutaneous implantable cardioverter-defibrillator with the real costs of hospitalization analysis in a single Polish center.
    Cardiol J 2018 Apr 3. Epub 2018 Apr 3.
    Medical University of Warsaw, Poland.
    Background: The recent introduction of an entirely subcutaneous implantable cardioverter-defibrillator (S-ICD) represents an important progress in the defibrillation technology towards a less invasive approach. This is a single-center observational study of S-ICD implantations in Poland.

    Methods: The S-ICD was implanted in 11 patients with standard indications for an ICD. Read More

    Epidemiology and chronobiology of out-of-hospital cardiac arrest in a subpopulation of southern Poland: A two-year observation.
    Cardiol J 2018 Apr 3. Epub 2018 Apr 3.
    Department of Cardiology and Internal Medicine, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Poland.
    Background: Although recent studies indicate temporal variations in the incidence of out-of-hospital cardiac arrest (OHCA), the Polish experience in this research is scarce to date. Epidemiology of OHCA and circadian is evaluated herein, weekly and seasonal variations of OHCA frequency among the adult population of the Opole district, Poland.

    Methods: The retrospective analysis of 815 OHCA cases with presumed cardiac etiology was made based on dispatch cards from the Emergency Medical Center in Opole registered during a 2 year period (2006-2007). Read More

    The relationship between pulse waveform analysis indices, endothelial function and clinical outcomes in patients with peripheral artery disease treated using percutaneous transluminal angioplasty during a one-year follow-up period.
    Cardiol J 2018 Apr 3. Epub 2018 Apr 3.
    Cardiovascular Diseases Department, Jagiellonian University Medical College, Krakow, Poland.
    Background: The aim of the current study was to assess the relationship between potential predictors of clinical outcomes after percutaneous transluminal angioplasty (PTA) of peripheral arteries during a one-year follow-up. Indices of endothelial function (EF), arterial pulse waveform analysis (aPWA) and markers of peripheral arteries ischemia were among those mostly examined.

    Methods: The study comprised of 72 individuals with PAD who underwent PTA of the peripheral arteries. Read More

    Prevention of in-stent restenosis with endothelial progenitor cell (EPC) capture stent placement combined with regional EPC transplantation: An atherosclerotic rabbit model.
    Cardiol J 2018 Apr 3. Epub 2018 Apr 3.
    The Affiliated Wujin Hospital, Jiang University, 2nd North Yonging Road, 213017 Changzhou, China.
    Background: Even with drug-eluting stents, the risk of in-stent restenosis (ISR) remains high. The goal of this study was to investigate the use of an endothelial progenitor cell (EPC) capture stent plus regional EPC transplantation to reduce the ISR rate.

    Methods: Endothelial progenitor cell capture stents were fabricated using fibrin gel and anti-CD34 plus anti-VEGFR-2 dual antibodies. Read More

    Percutaneous renal artery denervation in patients with chronic systolic heart failure: a randomized controlled trial.
    Cardiol J 2018 Apr 3. Epub 2018 Apr 3.
    Department of Cardiology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine.
    B: ACKGROUND: Renal denervation (RDN) is as an effective treatment for heart failure, but its effects on cardiac function of patients with heart failure (HF) are not well documented. Here, the aim was to investigate RDN's effect on patients with chronic systolic HF, by conducting a single-center, prospective, randomized, and controlled study. M: ETHODS: Sixty patients with chronic systolic HF were randomly assigned to the RDN or control groups, receiving percutaneous catheter-based RDN with radiofrequency ablation and drug treatment respectively. Read More

    Feasibility of zero or near zero fluoroscopy during catheter ablation procedures.
    Cardiol J 2018 Apr 3. Epub 2018 Apr 3.
    University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland.
    Background: Awareness of risks associated with radiation exposure to patients and medical staff has significantly increased. It has been reported before that the use of advanced three-dimensional electro-anatomical mapping (EAM) system significantly reduces fluoroscopy time, however this study aimed for zero or near zero fluoroscopy ablation to assess its feasibility and safety in ablation of atrial fibrillation (AF) and other tachyarrhythmias in a "real world" experience of a single tertiary care center.

    Methods: This was a single-center study where ablation procedures were attempted without fluoroscopy in 34 consecutive patients with different tachyarrhythmias under the support of EAM system. Read More

    Increased plasma cathepsin S and trombospondin-1 in patients with acute ST segment elevation myocardial infarction.
    Cardiol J 2018 Apr 3. Epub 2018 Apr 3.
    Department of Laboratory Medicine, , Örebro University hospital,, 70185, Örebro, Sweden.
    Background: The role of cathepsins in the pathological progression of atherosclerotic lesions in ischemic heart disease have been defined in detail more than numerous times. This investigation examined the platelet-specific biomarker trombospondin-1 (TSP-1) and platelet function ex vivo, and compared this with cathepsin S (Cat-S; a biomarker unrelated to platelet activation but also associated this with increased mortality risk) in patients with ST segment elevation myocardial infarction (STEMI).

    Methods: The STEMI patients were divided into two groups depending on the degree of coronary vessel occlusion: those with closed (n = 90) and open culprit vessel (n = 40). Read More

    The impact of renal function on the prognostic value of N-terminal B-type natriuretic peptide in patients with coronary artery disease.
    Cardiol J 2018 Apr 3. Epub 2018 Apr 3.
    West China Hospital of Sichuan University, 37 Guo Xue Xiang, 610041 chengdu, China.
    Background: The impact of renal function on the prognostic value of N-terminal B-type natriuretic peptide (NT-proBNP) remains unclear in coronary artery disease (CAD). This study sought to investigate the value of using NT-proBNP level to predict prognoses of CAD patients with different estimated glomerular filtration rates (eGFRs).

    Methods: A retrospective analysis was conducted from a single registered database. Read More

    Proteomics study of serum exosomes in Kawasaki disease patients with coronary artery aneurysms.
    Cardiol J 2018 Apr 3. Epub 2018 Apr 3.
    Guangzhou Women and Children' s Medical Center, China.
    Background: To study the protein profile of the serum exosomes of patients with coronary artery aneurysms (CAA) caused by Kawasaki disease (KD).

    Methods: Two-dimensional electrophoresis (2-DE) was used to identify proteins from the exosomes of serum obtained from children with CAA caused by KD, as well as healthy controls. Differentially expressed proteins were identified using matrix-assisted laser desorption/ionization time-of-flight/time-of-flight mass spectrometry (MALDI-TOF/TOF MS) analysis. Read More

    Diagnostic and prognostic value of QRS duration and QTc interval in patients with suspected myocardial infarction.
    Cardiol J 2018 04 3. Epub 2018 Apr 3.
    University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland.
    Background: While prolongation of QRS duration and QTc interval during acute myocardial infarction (AMI) has been reported in animals, limited data is available for these readily available electrocardiography (ECG) markers in humans.

    Methods: Diagnostic and prognostic value of QRS duration and QTc interval in patients with suspected AMI in a prospective diagnostic multicentre study were prospectively assessed. Digital 12-lead ECGs were recorded at presentation. Read More

    Invasive reperfusion after 12 hours of the symptom onset remains beneficial in patients with ST-segment elevation myocardial infarction: Evidence from a meta-analysis of published data.
    Cardiol J 2018 Apr 3. Epub 2018 Apr 3.
    Xinjiang Medical University.
    Background: Early myocardial reperfusion therapy ( < 12 h) in patients with acute myocardial infarction (AMI) can significantly improve their prognosis. However, the effect of late reperfusion ( > 12 h) remains controversial. In this study, the effects of late reperfusion versus standard drug therapy on the outcomes of patients with AMI were evaluated by systematic review and meta-analysis. Read More

    Thermic sealing in femoral catheterisation: First experience with the Secure Device.
    Cardiol J 2018 Apr 3. Epub 2018 Apr 3.
    Medical University of Graz.
    Background: Devices currently used to achieve hemostasis of the femoral artery following percutaneous cardiac catheterization are associated with vascular complications and remnants of artificial materials are retained at the puncture site. The SECURE arterial closure device induces hemostasis by utilizing thermal energy, which causes collagen shrinking and swelling. In comparison to established devices, it has the advantage of leaving no foreign material in the body following closing. Read More

    How does the risk of cardiovascular death and cardiovascular risk factor profiles differ between socioeconomic classes in Poland: A country in transition.
    Cardiol J 2018 Mar 23. Epub 2018 Mar 23.
    Third Department of Cardiology, Medical University of Silesia, Ziolowa 47, 40-635 Katowice, Poland.
    Background: Socioeconomic status (SES) is an important factor of cardiovascular diseases (CVD) development. A decline in death from CVD among subjects with high SES is observed in developed countries. The aim of this study was to assess differences in cardiovascular risk between socioeconomic classes in Poland, a country currently in transition. Read More

    Valve in valve implantation of the CoreValve Evolut R in degenerated surgical aortic valves.
    Cardiol J 2018 Mar 23. Epub 2018 Mar 23.
    Department of Cardiology, Charité - Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, Germany.
    Background: The new CoreValve Evolut R has an improved design to minimize paravalvular leakage (PVL) and allows repositioning of the valve. For patients with degenerated bioprosthetic aortic valves, transcatheter aortic valve implantation (TAVI) represents a less invasive option. Herein reported are valve-in-valve (ViV) implantations of this new valve. Read More

    Medium and long-term prognosis of transcatheter aortic valve implantation from the perspective of left ventricular diastolic function.
    Cardiol J 2018 Mar 23. Epub 2018 Mar 23.
    Teikyo University School of Medicine, 2-11-1 Kaga,Itabashi,Tokyo, 1738605 Tokyo, Japan.
    Background: The effects of left ventricular (LV) diastolic function are well known in cardiac surgery, but unclear in transcatheter aortic valve implantation (TAVI). The objective of this study was to examine the association of preoperative LV diastolic function with medium to long-term outcomes of TAVI.

    Methods: Eighty patients who underwent TAVI were classified into grades I, II and III based on preoperative LV diastolic function. Read More

    Long-term outcomes of mitral valve annuloplasty versus subvalvular sparing replacement for severe ischemic mitral regurgitation.
    Cardiol J 2018 Mar 23. Epub 2018 Mar 23.
    Fuwai Hospital,National Center for Cardiovascular Disease, Chinese Academy of Medical Science, Peking Union Medical College.
    Background: Although practice guidelines recommend surgery for patients with severe chronic ischemic mitral regurgitation (CIMR), they do not specify whether to repair or replace the mitral valve. The purpose of this study was to evaluate the long-term outcomes in patients with severe CIMR undergoing mitral valve annuloplasty (MVA) versus subvalvular sparing mitral valve replacement (MVR).

    Methods: 392 consecutive patients who underwent MVA or subvalvular sparing MVR for treatment of severe CIMR were retrospectively reviewed. Read More

    Sheep can be used as animal model of regional myocardial remodelling and controllable work.
    Cardiol J 2018 Mar 23. Epub 2018 Mar 23.
    KU Leuven - University of Leuven, Herestraat 49, 3000 Leuven, Belgium.
    Background: A-V-sequential pacing has been shown to induce reversible conduction delay and subsequent asymmetric remodelling of the left ventricle (LV) in dogs and pigs. Both species have disadvantages in animal experiments. Therefore aim of this study focusses at developing a more feasible and easy-to-use animal model in sheep. Read More

    Silencing of c-Ski augments TGF-β1-induced epithelial-mesenchymal transition in cardiomyocyte H9C2 cells.
    Cardiol J 2018 Mar 23. Epub 2018 Mar 23.
    The First People's Hospital of Shanghai, 100# Hongkou District, Shanghai, 200082 Shanghai, China.
    Background: The shRNA lentiviral vector was constructed to silence c-Ski expression in cardiac muscle cells, with the aim of exploring the role of c-Ski in transforming growth factor β1 (TGF-β1)-induced epithelial-mesenchymal transitions (EMT) in H9C2 cells.

    Methods: RT-PCR and western blot were used to detect c-Ski expression at protein and messenger ribonucleic acid (mRNA) levels in 5 different cell lines. Then, lentiviral vector was constructed to silence or overexpress c-Ski in H9C2 cells. Read More

    Intra-ventricular thrombus resolution after anticoagulation therapy with rivaroxaban in patient with poor anticoagulation quality.
    Cardiol J 2018 ;25(1):151-154
    Department of Cardiology. Hospital Universitario Virgen de la Arrixaca, Ctra. Madrid-Cartagena s/n, 30120 Murcia, Spain; Instituto de Investigación Biosanitaria (IMIB-Arrixaca), CIBER-CV, Spain.

    Effects of hyperbaric oxygen on vascular endothelial function in patients with slow coronary flow.
    Cardiol J 2018 ;25(1):106-112
    Department of Cardiology, The Third Hospital of Hebei Medical University.
    Background: To improve therapy for slow coronary flow (SCF), the effects of hyperbaric oxygen (HBO) therapy on vascular endothelial function in SCF patients is the focus of this investigation.

    Methods: Ninety-eight patients who exhibited chest discomfort were retrospectively analyzed, and di-agnosed with SCF by coronary artery angiography at the Third Hospital of Hebei Medical University, Shijiazhuang, China from 2014 to 2016. The patients were divided into two groups according to the following treatment: HBO group (n = 48) and the control group (n = 50). Read More

    Patent foramen ovale closure versus medical therapy after cryptogenic stroke: An updated meta-analysis of all randomized clinical trials.
    Cardiol J 2018 Mar 7. Epub 2018 Mar 7.
    Hurley Medical Center/Michigan State University.
    Background: Cryptogenic strokes can be attributed to paradoxical emboli through patent foramen ovale (PFO). However, the effectiveness of PFO closure in preventing recurrent stroke is uncertain and the results of previous randomized clinical trials (RCTs) have been inconclusive. Hence, this study provides an updated meta-analysis of all RCTs comparing PFO closure with medical therapy for secondary prevention of cryptogenic stroke. Read More

    Predictive value of CHA2DS2-VASc and CHA2DS2-VASc-HS scores for failed reperfusion after thrombolytic therapy in patients with ST-elevation myocardial ınfarction.
    Cardiol J 2018 Mar 7. Epub 2018 Mar 7.
    Doctor Ersin Aslan Research and Training Hospital, Şahinbey, Gaziantep, Turkey.
    Background: Thrombolytic therapy is recommended for patients with acute ST-segment elevation myocardial infarction (STEMI) who cannot undergo primary percutaneous coronary intervention within the first 120 min. The aim of this study wasz to demonstrate the value of CHA₂DS₂-VASc and CHA₂DS₂-VASc-HS scores in predicting failed reperfusion in STEMI patients treated with thrombolytic therapy.

    Methods: A total of 537 consecutive patients were enrolled in the study; 139 had failed thrombolysis while the remaining 398 fulfilled the criteria for successful thrombolysis. Read More

    Mast cell derived carboxypeptidase A3 is decreased among patients with advanced coronary artery disease.
    Cardiol J 2018 Mar 7. Epub 2018 Mar 7.
    University Center for Cardiology, Gdansk, Poland; Gdansk University of Technology, Gdansk, Poland; Pomeranian Cardiology Centers, Wejherowo, Poland, Dębinki 2, 80-211 Gdańsk, Poland.
    Background: Coronary artery disease (CAD) affects milions of people and can result in myocardial infarction (MI). Previously, mast cells (MC) have been extensively investigated in the context of hypersensitivity, however as regulators of the local inflammatory response they can potentially contribute to CAD and/or its progression. The aim of the study was to assess if serum concentration of MC proteases: carboxypeptidase A3, cathepsin G and chymase 1 is associated with the extension of CAD and MI. Read More

    Two-dimensional versus three-dimensional transesophageal echocardiography in percutaneous left atrial appendage occlusion.
    Cardiol J 2018 Mar 7. Epub 2018 Mar 7.
    1st Department of Cardiology, Congenital Heart Diseases and Electrotherapy, Silesian Center for Heart Diseases, Curie-Sk lodowskiej 9, 41-800 Zabrze, Poland.
    Background: Real-time three-dimensional transesophageal echocardiography (RT3D TEE) enables better visualization of the left atrial appendage (LAA) and may be superior to real-time two-dimensional transesophageal echocardiography (RT2D TEE) for LAA occlusion (LAAO). The aim of this study was to assess inter- and intra-observer variability of RT2D TEE and RT3D TEE measurements of LAA, and to assess the accordance of RT2D TEE and RT3D TEE with appropriate occluder selection.

    Methods: Transesophageal echocardiography was performed in 40 patients during LAAO. Read More

    Predictive and protective role of high-density lipoprotein cholesterol in acute myocardial infarction.
    Cardiol J 2018 Mar 7. Epub 2018 Mar 7.
    Medical Research Institute, Pusan National University Hospital.
    Background: It is unclear whether high-density lipoprotein cholesterol (HDL-C) level predicts cardiovascular events and has a protective effect in patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI) and statin treatment.

    Methods: A total of 15,290 AMI patients receiving statins were selected from the Korean Myocardial Infarction Registry. Baseline HDL-C level was used to identify patients with low (Group A), normal (B), and high (C) HDL-C levels according to the Adult Treatment Panel III criteria. Read More

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