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    3378 results match your criteria Cardiology in the Young[Journal]

    1 OF 68

    Additional mechanism for left ventricular dysfunction: chronic pulmonary regurgitation decreases left ventricular preload in patients with tetralogy of Fallot.
    Cardiol Young 2017 Oct 11:1-6. Epub 2017 Oct 11.
    1Children's Hospital,University of Helsinki,Helsinki University Central Hospital,Helsinki,Finland.
    Background: Right ventricular dysfunction in patients with tetralogy of Fallot and significant pulmonary regurgitation may lead to systolic dysfunction of the left ventricle due to altered ventricular interaction. We were interested in determining whether chronic pulmonary regurgitation affects the preload of the left ventricle. In addition, we wanted to study whether severe chronic pulmonary regurgitation would alter the preload of the left ventricle when compared with patients having preserved pulmonary valve annulus. Read More

    Evolution of the concept of oxygen transport in the critically ill, with a focus on children after cardiopulmonary bypass.
    Cardiol Young 2017 Oct 11:1-6. Epub 2017 Oct 11.
    Clinical Physiology Research Center,Capital Institute of Pediatrics,Beijing,China.
    The concept of oxygen transport, defined as the relation between oxygen consumption (VO2) and delivery (DO2), is of fundamental importance in critically ill patients. The past 200 years have witnessed a stepwise progressive improvement in the understanding of pathophysiological disturbances in the balance of DO2 and VO2 in critically ill patients including those after cardiopulmonary bypass surgery. Intermittent spectacular technological achievements have accelerated the rate of progress. Read More

    Infants born with critical CHD in Arizona and capacities of birth centres for screening and management.
    Cardiol Young 2017 Oct 11:1-8. Epub 2017 Oct 11.
    4John's Hopkins All Children's Heart Institute,St. Petersburg,Florida,United States of America.
    Objectives: The aims of this study were to identify locations of births in Arizona with critical CHD, as well as to assess the current use of pulse-oximetry screening and capacities of birth centres to manage a positive screen. Study design Infants (n=487) with a potentially critical CHD were identified from the Arizona Department of Health Services from 2012 and 2013; charts were retrospectively reviewed. Diagnosis was confirmed using echocardiographies. Read More

    Challenges for bilateral pulmonary artery stenting due to occluded femoral veins.
    Cardiol Young 2017 Oct 11:1-3. Epub 2017 Oct 11.
    Department of Pediatric Cardiology,Institute of Cardio Vascular Diseases,Madras Medical Mission,Chennai,Tamil Nadu,India.
    When the inferior caval vein is occluded or abnormal, jugular and hepatic veins provide alternative routes for interventions. For pulmonary artery stenting, transhepatic access may give a relatively straighter route than that from the jugular veins. We describe the challenges and strategies during transhepatic bilateral pulmonary artery stenting after arterial switch operation complicated by occluded inferior caval vein and congested hepatic veins. Read More

    Comparison of the therapeutic effects and side effects of tadalafil and sildenafil after surgery in young infants with pulmonary arterial hypertension due to systemic-to-pulmonary shunts.
    Cardiol Young 2017 Nov;27(9):1686-1693
    1Pediatric Department,Isfahan University of Medical Sciences,Isfahan,Iran.
    Young children with CHD and large systemic-to-pulmonary shunts eventually develop pulmonary hypertension. At present, phosphodiesterase type-5 inhibitors such as sildenafil have been used to control pulmonary pressure before and after cardiac surgery. Recently, tadalafil has been utilised in older children with similar efficacy, but it has been used to a lesser extent in young infants. Read More

    Is mesocardia with left-sided caval vein draining to coronary sinus a contraindication for a percutaneous pulmonary valve implantation? A case description.
    Cardiol Young 2017 Oct 4:1-5. Epub 2017 Oct 4.
    1Centre for Congenital Heart Disease,Heart and Diabetes Centre,Bad Oeynhausen,Ruhr University of Bochum,North Rhine Westphalia,Germany.
    Introduction Although the right jugular vein approach for percutaneous pulmonary valve implantation is well described, there are no reports that describe a percutaneous pulmonary valve implantation through a left superior caval vein to coronary sinus pathway. Case A 14-year-old female with tetralogy of Fallot, mesocardia, left superior caval vein draining into the coronary sinus, and hemiazygos continuation of the inferior caval vein underwent ventricular septal defect closure, with homograft insertion from the right ventricle to the pulmonary artery, patch augmentation of the left pulmonary artery, and creation of an atrial communication. Thereafter followed numerous catheterisations and interventions with stent implantation for stenosis of the left pulmonary artery and the homograft, as did device closure of the atrial communication. Read More

    A vascular endothelial growth factor A genetic variant is associated with improved ventricular function and transplant-free survival after surgery for non-syndromic CHD.
    Cardiol Young 2017 Sep 20:1-7. Epub 2017 Sep 20.
    1Department of Cardiothoracic Surgery,The Children's Hospital of Philadelphia,Philadelphia,Pennsylvania,United States of America.
    Background: We have previously shown that the minor alleles of vascular endothelial growth factor A (VEGFA) single-nucleotide polymorphism rs833069 and superoxide dismutase 2 (SOD2) single-nucleotide polymorphism rs2758331 are both associated with improved transplant-free survival after surgery for CHD in infants, but the underlying mechanisms are unknown. We hypothesised that one or both of these minor alleles are associated with better systemic ventricular function, resulting in improved survival.

    Methods: This study is a follow-up analysis of 422 non-syndromic CHD patients who underwent neonatal cardiac surgery with cardiopulmonary bypass. Read More

    Educational level and employment status in adults with congenital heart disease.
    Cardiol Young 2017 Sep 13:1-7. Epub 2017 Sep 13.
    1Department of Congenital Heart Disease - Paediatric Cardiology,Deutsches Herzzentrum Berlin,Germany.
    Purpose Through this study we aimed to assess the educational level and employment status of adults with CHD in Germany.

    Methods: Data were acquired from an online survey carried out in 2015 by the German National Register for Congenital Heart Defects. A total of 1458 adults with CHD participated in the survey (response rate: 37. Read More

    Acute kidney injury following first-stage palliation in hypoplastic left heart syndrome: hybrid versus Norwood palliation.
    Cardiol Young 2017 Sep 11:1-8. Epub 2017 Sep 11.
    4Division of Cardiology,Carman and Ann Adams Department of Pediatrics,Children's Hospital of Michigan,Wayne State University School of Medicine,Detroit,Michigan,United States of America.
    Objective: The aim of this study was to evaluate the prevalence of acute kidney injury after first-stage surgical palliation in patients with a single ventricle and to explore associated risk factors and outcomes. Design and patients This single-centre retrospective study included neonates who underwent either Norwood or Hybrid procedure from 2008 to 2015 for a single ventricle. Postoperative acute kidney injury was defined using the paediatric risk, injury, failure, loss, end-stage renal disease (pRIFLE), criteria within 72 hours of the procedure. Read More

    Endocarditis of a congenital coronary fistula in a child.
    Cardiol Young 2017 Sep 11:1-4. Epub 2017 Sep 11.
    Sophia Kinderziekenhuis,Department of Pediatric Cardiology,Erasmus Medical Centre Rotterdam,Rotterdam,The Netherlands.
    Endocarditis of congenital coronary fistulas in the cardiac chambers is rare, especially in the paediatric age group. We describe the case of a 9-year-old boy with a fistula from the dilated right coronary artery to the junction of the superior caval vein to the right atrium, complicated by endocarditis. Treatment consisted of 6 weeks of antibiotics and interventional closure of the fistula 3 months later with an Amplatzer vascular plug. Read More

    Neutrophil gelatinase-associated lipocalin reflects inflammation and is not a reliable renal biomarker in neonates and infants after cardiopulmonary bypass: a prospective case-control study.
    Cardiol Young 2017 Sep 11:1-9. Epub 2017 Sep 11.
    2Department of Pediatric Cardiology and Congenital Heart Disease,Deutsches Herzzentrum Muenchen,Technische Universitaet,Germany.
    Introduction Acute kidney injury is a frequent complication after cardiac surgery with cardiopulmonary bypass in infants. Neutrophil gelatinase-associated lipocalin has been suggested to be a promising early biomarker of impending acute kidney injury. On the other hand, neutrophil gelatinase-associated lipocalin has been shown to be elevated in systemic inflammatory diseases without renal impairment. Read More

    Atrial septal defect morphology and stenting in hypoplastic left heart syndrome after hybrid palliation.
    Cardiol Young 2017 Sep 11:1-9. Epub 2017 Sep 11.
    3Bambino Gesù Pediatric Hospital,Medical and Surgical Department of Pediatric Cardiology,Rome,Italy.
    Aims The aim of this study was to describe atrial septal defect morphology in hypoplastic left heart syndrome, to report the incidence of restrictiveness and its relationship with defect morphology, to correlate restriction with midterm outcome, and to describe our interventional approach to restrictive defect. Methods and results From 2011 to 2015, 31 neonates with hypoplastic left heart syndrome underwent hybrid procedure with pulmonary artery banding and ductal stenting at our Institution. Restrictive physiology of the atrial septal defect was based on Doppler gradient >6 mmHg through the defect and on clinical signs of pulmonary hypertension. Read More

    Multidisciplinary family-centred psychosocial care for patients with CHD: consensus recommendations from the AEPC Psychosocial Working Group.
    Cardiol Young 2017 Sep 11:1-7. Epub 2017 Sep 11.
    6Department of Child Health,Queen's University,Belfast,Northern Ireland.
    Because of the enormous advances in the medical treatment of CHD, the long-term survival of patients suffering from this disease has increased significantly. Currently, about 90% of patients reach adulthood, which entails many new challenges both for patients and their families and for healthcare professionals. The main objective of family-centred psychosocial care is to strengthen the emotional resilience of chronically ill patients and their families by adopting a holistic approach. Read More

    Recombinant factor VIIa as a rescue therapy in severe haemoptysis in a patient with a Fontan circulation.
    Cardiol Young 2017 Sep 11:1-3. Epub 2017 Sep 11.
    2Adult Congenital Cardiology,St Thomas' Hospital, Guys and St Thomas' NHS foundation trust,London,United Kingdom.
    We describe the successful use of recombinant factor VIIa (rFVIIa) in the control of massive haemoptysis in a 17-year-old patient with a Fontan circulation. The patient was intubated and ventilated in the ICU with deteriorating gas exchange. Conventional methods to control the haemoptysis were ineffective, and rFVIIa was successfully administered as a rescue therapy. Read More

    Enhancement of diuresis with metolazone in infant paediatric cardiac intensive care patients.
    Cardiol Young 2017 Sep 11:1-5. Epub 2017 Sep 11.
    2Department of Pediatrics,Baylor College of Medicine,Houston,Texas,United States of America.
    Background: Few data are available regarding the use of metolazone in infants in cardiac intensive care. Researchers need to carry out further evaluation to characterise the effects of this treatment in this population.

    Methods: This is a descriptive, retrospective study carried out in patients less than a year old. Read More

    Differences in clinical outcomes and cost between complex and simple arterial switches.
    Cardiol Young 2017 Sep 11:1-8. Epub 2017 Sep 11.
    1Division of Pediatric Cardiac Surgery,University of Utah,Salt Lake City,Utah,United States of America.
    Background: This study evaluates the morbidity, mortality, and cost differences between patients who underwent either a simple or a complex arterial switch operation.

    Methods: A retrospective study of patients undergoing an arterial switch operation at a single institution was performed. Simple cases were defined as patients with d-transposition of the great arteries with usual coronary anatomy or circumflex artery originating from the right with either intact ventricular septum or ventricular septal defect. Read More

    Thoracoscopic treatment of left-to-right shunt in a child with scimitar syndrome.
    Cardiol Young 2017 Sep 11:1-4. Epub 2017 Sep 11.
    Department of Pediatric Surgery,Ege Universitesi Tip Fakultesi,Izmir,Turkey.
    Scimitar syndrome represents a rare variant of partial anomalous pulmonary venous connection with right lung hypoplasia, dextrocardia, and concomitant airway-vessel abnormalities. Surgical correction is preferred in symptomatic patients or in patients with increased left-to-right shunt. In this report, the first case of scimitar syndrome with dual arterial supply and venous drainage to be treated with thoracoscopic approach is presented. Read More

    Efficacy and safety of recombinant tissue plasminogen activator for venous thrombosis after paediatric heart surgery.
    Cardiol Young 2017 Sep 11:1-8. Epub 2017 Sep 11.
    1The Heart Institute,Cincinnati Children's Hospital Medical Center,Cincinnati,Ohio,United States of America.
    Objective: Reports in the literature of treatment with recombinant tissue plasminogen activator following cardiac surgery are limited. We reviewed our experience to provide a case series of the therapeutic use of tissue plasminogen activator for the treatment of venous thrombosis in children after cardiac surgery. The data describe the morbidity, mortality, and clinical outcomes of tissue plasminogen activator administration for treatment of venous thrombosis in children following cardiac surgery. Read More

    First-stage palliation strategy for univentricular heart disease may impact risk for acute kidney injury.
    Cardiol Young 2017 Sep 11:1-8. Epub 2017 Sep 11.
    1The Heart Institute,Cincinnati Children's Hospital Medical Center,Cincinnati,Ohio,United States of America.
    Objective: Norwood palliation for patients with single ventricle heart disease is associated with a significant risk for acute kidney injury, which portends a worse prognosis. We sought to investigate the impact of hybrid stage I palliation (Hybrid) on acute kidney injury risk.

    Design: This study is a single-centre prospective case-control study of seven consecutive neonates with single ventricle undergoing Hybrid palliation. Read More

    Unique levoatriocardinal veins in neonates with hypoplastic left heart syndrome and intact atrial septum.
    Cardiol Young 2017 Sep 11:1-3. Epub 2017 Sep 11.
    Department of Pediatrics,Japan Community Healthcare Organization Kyushu Hospital,Kitakyushu,Japan.
    We had two cases of neonates with hypoplastic left heart syndrome and intact atrial septum who had unique levoatriocardinal veins. Contrast-enhanced CT and angiography revealed that previously unknown communicating vessels ran from the top of the left atrium and drained into the right atrium. We emphasise that transcatheter atrial septostomy should be performed not through these communicating vessels but using the trans-septal approach in neonates with hypoplastic left heart syndrome and an intact atrial septum. Read More

    A focussed single-view hand-held echocardiography protocol for the detection of rheumatic heart disease.
    Cardiol Young 2017 Sep 11:1-10. Epub 2017 Sep 11.
    2Children's National Health System,Washington,District of Columbia,United States of America.
    Background: Echocardiographic screening represents an opportunity for reduction in the global burden of rheumatic heart disease. A focussed single-view screening protocol could allow for the rapid training of healthcare providers and screening of patients.

    Objective: The aim of this study was to determine the sensitivity and specificity of a focussed single-view hand-held echocardiographic protocol for the diagnosis of rheumatic heart disease in children. Read More

    Cardiovascular CT for evaluation of single-ventricle heart disease: risks and accuracy compared with interventional findings.
    Cardiol Young 2017 Sep 11:1-12. Epub 2017 Sep 11.
    1Advanced Cardiac Imaging,Minneapolis Heart Institute and Foundation,Minneapolis,Minnesota,United States of America.
    Objective: We sought to evaluate the risk and image quality from cardiovascular CT in patients across all stages of single-ventricle palliation, and to define accuracy by comparing findings with intervention and surgery.

    Methods: Consecutive CT scans performed in patients with single-ventricle heart disease were retrospectively reviewed at a single institution. Diagnosis, sedation needs, estimated radiation dose, and adverse events were recorded. Read More

    Percutaneous closure of aorta-right atrial tunnel in a newborn.
    Cardiol Young 2017 Sep 8:1-2. Epub 2017 Sep 8.
    Division of Pediatric Cardiology,Erciyes University School of Medicine,Kayseri,Turkey.
    A tunnel between the aorta and right atrium in a newborn was occluded with 5×6 Amplatzer Duct Occluder II-Additional Size. Our case is different because of enlarged right atrium and atypical location of tunnel orifice. Read More

    A rapid echocardiographic screening protocol for rheumatic heart disease in Samoa: a high prevalence of advanced disease.
    Cardiol Young 2017 Oct;27(8):1599-1605
    4Department of Biology,Brigham Young University,Provo,Utah,United States of America.
    Background: Echocardiography has been proposed as a method to screen children for rheumatic heart disease. The World Heart Federation has established guidelines for echocardiographic screening. In this study, we describe a rapid echocardiogram screening protocol according to the World Heart Federation guidelines in Samoa, endemic for rheumatic heart disease. Read More

    Down syndrome and transposition of the great arteries.
    Cardiol Young 2017 Oct;27(8):1630-1632
    Paediatric Cardiology Clark Clinic,Royal Belfast Hospital for Sick Children,Belfast,BT12 6BE,Northern Ireland.
    There is an old adage in paediatric cardiology that, despite the high prevalence and wide spectrum of CHD, transposition of the great arteries does not occur in trisomy 21. We present a case of transposition of the great arteries, ventricular septal defect, and pulmonary stenosis in a patient with trisomy 21. Read More

    Fungal endocarditis in paediatrics: a review of 192 cases (1971-2016).
    Cardiol Young 2017 Oct;27(8):1481-1487
    Velammal Medical College Hospital and Research Institute,Microbiology and Interventional Cardiology,Velammal Village,Tuticorin Ring Road,Anuppanadi,Madurai,TN,India.
    Background: The aims of this article were to review the published literature on fungal endocarditis in children and to discuss the aetiology and diagnosis, with emphasis on non-invasive methods and various treatment regimes.

    Methods: We systematically reviewed published cases and case series of fungal endocarditis in children. We searched the literature, including PubMed and individual references for publications of original articles, single cases, or case series of paediatric fungal endocarditis, with the following keywords: "fungal endocarditis", "neonates", "infants", "child", and "cardiac vegetation". Read More

    Initial assessment of a novel delivery system (NuDEL™ ®) for the covered Cheatham-Platinum stent.
    Cardiol Young 2017 Oct;27(8):1465-1469
    1Departments of Paediatric and Adult Congenital Cardiology,Evelina London Children's Hospital,Guy's and St Thomas' NHS Foundation Trust,King's College London,London, United Kingdom.
    Aims We sought to evaluate the first-in-man use of a new system for implantation of covered stents in patients with complex structural and CHD. Methods and results Retrospective data were collected of the first 13 NuDEL™ delivery systems used in patients. The NuDEL™ comprises a covered Cheatham-Platinum stent mounted on a balloon-in-balloon and pre-loaded in a long delivery sheath. Read More

    Persistent fifth aortic arch: the "great pretender" in clinical practice.
    Cardiol Young 2017 Aug 30:1-7. Epub 2017 Aug 30.
    1Department of Congenital Heart Disease,Royal Brompton Hospital,London,United Kingdom.
    Persistence of the embryonic "fifth aortic arch" in postnatal life is a rare, enigmatic - and at times controversial - condition, with variable anatomical forms and physiological consequences. First described in humans over 40 years ago by Van Praagh, the condition was labelled the "great pretender" by Gerlis 25 years later, because of its apparent propensity to mimic anatomically similar structures. Despite many subsequent case reports citing the condition, the true developmental origin of these structures remains unresolved, and has been the subject of debate among embryologists for more than a century. Read More

    Giant coronary artery aneurysms complicating Kawasaki disease in Mexican children.
    Cardiol Young 2017 Aug 29:1-5. Epub 2017 Aug 29.
    4Teaching Department,National Institute of Paediatrics,Mexico City,Mexico.
    Background: One of the most important complications of Kawasaki disease is the development of giant coronary aneurysms. Risk factors for their development are still not clear.

    Methods: A retrospective analysis was conducted at the National Institute of Paediatrics in Mexico City, Mexico. Read More

    Femoral vein homograft as Sano shunt results in improved pulmonary artery growth after Norwood operation.
    Cardiol Young 2017 Aug 29:1-8. Epub 2017 Aug 29.
    2Department of Cardiothoracic Surgery,Le Bonheur Children's Hospital and University of Tennessee Health Science Center,Memphis,Tennessee,United States of America.
    Objective: To evaluate differences in interstage growth of pulmonary arteries between use of polytetrafluoroethylene and femoral vein homograft as Sano shunt during stage-I Norwood palliation.

    Methods: A retrospective review of all patients who survived to the second stage following Norwood-Sano operation at two institutions was performed. Either polytetrafluoroethylene or the valved segment of femoral vein homograft was used for construction of the Sano shunt. Read More

    Asymptomatic atresia of the anomalous pulmonary vein in a patient with scimitar syndrome presenting in childhood.
    Cardiol Young 2017 Aug 29:1-5. Epub 2017 Aug 29.
    3Department of Pediatrics,Division of Cardiology Children's National Medical Center,George Washington University School of Health Sciences,Washington,District of Columbia,United States of America.
    An asymptomatic 6-year-old boy with a history of right lung hypoplasia was referred for cardiology evaluation. Echocardiography demonstrated right pulmonary artery hypoplasia with flow reversal in that vessel. The right pulmonary veins were not visualised in the echocardiogram. Read More

    Utilisation of early intervention services in young children with hypoplastic left heart syndrome.
    Cardiol Young 2017 Aug 29:1-8. Epub 2017 Aug 29.
    17National Heart, Lung, and Blood Institute,Bethesda,Pediatric Heart Network, Maryland,United States of America.
    Objective: Children with hypoplastic left heart syndrome are at a risk for neurodevelopmental delays. Current guidelines recommend systematic evaluation and management of neurodevelopmental outcomes with referral for early intervention services. The Single Ventricle Reconstruction Trial represents the largest cohort of children with hypoplastic left heart syndrome ever assembled. Read More

    Characterisation of three-dimensional mapping in Wolff-Parkinson-White syndrome with septal aneurysmal dyskinesis.
    Cardiol Young 2017 Aug 29:1-3. Epub 2017 Aug 29.
    3Department of Cardiology,Japan Community Healthcare Organization,Kyushu Hospital,Kitakyushu,Fukuoka,Japan.
    A 21-year-old man with Wolff-Parkinson-White syndrome and aneurysmal septal dyskinesis underwent radiofrequency catheter ablation of the accessory pathways. Before radiofrequency catheter ablation, the activation wavefront arose from the aneurysmal septum, whereas the propagation of the left ventricle was normalised after radiofrequency catheter ablation. These findings demonstrate the importance of the electro-mechanical interaction in patients with Wolff-Parkinson-White syndrome and ventricular dysfunction. Read More

    Punch-out lesion following regression of a large left ventricular outflow rhabdomyoma.
    Cardiol Young 2017 Aug 29:1-2. Epub 2017 Aug 29.
    Department of Pediatric Cardiology, Hadassah,Hebrew University Medical Center,Jerusalem,Israel.
    Abstracts We report the case of a patient with rhabdomyoma of the left ventricular outflow tract, causing severe obstruction at birth. The tumour regressed completely by 6 years of age, leaving a punch-out lesion. The potential for spontaneous regression of these tumours and the formation of a myocardial lesion following rhabdomyoma regression are discussed. Read More

    Feasibility of a healthcare system-based tetralogy of Fallot patient registry.
    Cardiol Young 2017 Aug 29:1-7. Epub 2017 Aug 29.
    1Department of Surgery,University of North Carolina School of Medicine,Chapel Hill,North Carolina,United States of America.
    Background: Patient-reported outcomes and epidemiological studies in adults with tetralogy of Fallot are lacking. Recruitment and longitudinal follow-up investigation across institutions is particularly challenging. Objectives of this study were to assess the feasibility of recruiting adult patients with tetralogy of Fallot for a patient-reported outcomes study, describe challenges for recruitment, and create an interactive, online tetralogy of Fallot registry. Read More

    Cardiac surgery in adults with high-surgical complexity CHD: results of a network collaborative programme.
    Cardiol Young 2017 Aug 29:1-7. Epub 2017 Aug 29.
    1Cardiovascular Department,Istituto Clinico Ligure di Alta Specialità (ICLAS),Rapallo,Italy.
    Background: Adults with CHD often exhibit complex cardiac abnormalities, whose management requires specific clinical and surgical expertise. To enable easier access of these patients to highly specialised care, we implemented a collaborative programme that incorporates medical and surgical specialists belonging to both paediatric and adult cardiovascular institutions.

    Objectives: The objective of this study was to review the experience gained and to analyse the surgical outcome of major cardiac surgery. Read More

    Premature ventricular contractions as a side effect of filgrastim in a child with B-thalassaemia.
    Cardiol Young 2017 Aug 29:1-4. Epub 2017 Aug 29.
    1Child Health Department,SQUH,Muscat,Oman.
    Premature ventricular contractions are a rare side effect of filgrastim, reported mainly in elderly men. Here we report the case of a 9-year-old child with thalassaemia who developed frequent premature ventricular contractions after three doses of filgrastim were given for deferiprone-induced agranulocytosis. The arrhythmia resolved 3 weeks after discontinuation of filgrastim. Read More

    Children with hypoplastic left heart syndrome have lower quality of life than healthy controls and children with other illnesses.
    Cardiol Young 2017 Aug 29:1-6. Epub 2017 Aug 29.
    1Nationwide Children's Hospital Columbus,Ohio,United States of America.
    Objective: Previous studies suggest that children with congenital cardiac diagnoses report lower quality of life when compared with healthy norms. A few studies have evaluated quality of life specifically in children born with hypoplastic left heart syndrome, a condition requiring several surgeries before age three. The aim of this study was to use an empirically validated and standardised measure - the Pediatric Quality of Life Inventory - to evaluate quality of life in children with hypoplastic left heart syndrome and compare the findings with similar, medically complicated samples. Read More

    "Giant within a giant": a case of typical Kawasaki disease with a giant coronary aneurysm and a large coronary thrombus - a rare case report.
    Cardiol Young 2017 Aug 24:1-3. Epub 2017 Aug 24.
    Department of Cardiology,Government Medical College Kozhikode,Kozhikode,Kerala,India.
    Kawasaki disease is a febrile vasculitis affecting young children, which may lead to coronary aneurysms. Echocardiography, although sensitive in detecting coronary aneurysms, has a limited role in diagnosing coronary thrombus. Here we report the case of a 10-year-old boy who presented with typical features of Kawasaki disease with giant coronary aneurysms. Read More

    Chylothorax following paediatric cardiac surgery: a case-control study.
    Cardiol Young 2017 Aug 24:1-7. Epub 2017 Aug 24.
    1Department of Cardiology,Royal Children's Hospital,Parkville,Victoria,Australia.
    Objectives: The aims of this study were to investigate risk factors for the development of postoperative chylothorax following paediatric congenital heart surgery and to investigate the impact of a management guideline on management strategies and patient outcome.

    Methods: All patients with chylothorax following cardiac surgery at the Royal Children's Hospital, Melbourne, over a 48-month period beginning in January 2008 were identified. A control group, matched for age, date of surgery, and sex, was identified. Read More

    Impaired cerebral autoregulation and elevation in plasma glial fibrillary acidic protein level during cardiopulmonary bypass surgery for CHD.
    Cardiol Young 2017 Aug 24:1-11. Epub 2017 Aug 24.
    4Johns Hopkins Hospital,Baltimore,Maryland,United Sates of America.
    Background: Cerebrovascular reactivity monitoring has been used to identify the lower limit of pressure autoregulation in adult patients with brain injury. We hypothesise that impaired cerebrovascular reactivity and time spent below the lower limit of autoregulation during cardiopulmonary bypass will result in hypoperfusion injuries to the brain detectable by elevation in serum glial fibrillary acidic protein level.

    Methods: We designed a multicentre observational pilot study combining concurrent cerebrovascular reactivity and biomarker monitoring during cardiopulmonary bypass. Read More

    Involvement of patients and parents in research undertaken by the Australian and New Zealand Fontan Registry.
    Cardiol Young 2017 Aug 17:1-5. Epub 2017 Aug 17.
    3Murdoch Children's Research Institute,Melbourne,Victoria,Australia.
    Research that is closely connected with the population it is studying and in which the translational value to healthcare is high is a laudable goal, but it is not often achieved. The Australian and New Zealand Fontan Registry has developed a model for involving patients and parents of children with a Fontan circulation in its research. The model involves consumer participation in the overarching Steering Committee, and has set in place multiple channels of communication allowing the early dissemination of research findings before peer-reviewing, and consumer feedback at all levels of the research. Read More

    Differential protein analysis of serum exosomes post-intravenous immunoglobulin therapy in patients with Kawasaki disease.
    Cardiol Young 2017 Nov 14;27(9):1786-1796. Epub 2017 Aug 14.
    3Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes,Institute of Life and Health Engineering,College of Life Science and Technology,Jinan University,Guangzhou 510632,Guangdong,China.
    Background: Kawasaki disease, which is characterised by systemic vasculitides accompanied by acute fever, is regularly treated by intravenous immunoglobulin to avoid lesion formation in the coronary artery; however, the mechanism of intravenous immunoglobulin therapy is unclear. Hence, we aimed to analyse the global expression profile of serum exosomal proteins before and after administering intravenous immunoglobulin.

    Methods: Two-dimensional electrophoresis coupled with mass spectrometry analysis was used to identify the differentially expressed proteome of serum exosomes in patients with Kawasaki disease before and after intravenous immunoglobulin therapy. Read More

    The history of paediatric cardiology on stamps.
    Cardiol Young 2017 Aug 14:1-8. Epub 2017 Aug 14.
    Department of Pediatric Cardiology,Ankara Children's Hematology,Oncology Education and Research Hospital,Ankara,Turkey.
    Paediatric cardiology is arguably the sub-specialty in which the greatest advances have been made in both disease diagnosis and treatment over the past half a century. Paediatric cardiology emerged as a discipline in the 1930s. Since then, advances in imaging techniques such as echocardiography, angiography, CT, or magnetic resonance and extracorporeal circulation have provided excellent diagnosis and treatment of CHD. Read More

    Intravenous sotalol use in a complex critically ill child: balancing the systems in choosing antiarrhythmic medication.
    Cardiol Young 2017 Nov 11;27(9):1857-1860. Epub 2017 Aug 11.
    Division of Pediatric Cardiology,University of Washington School of Medicine,Seattle Children's Hospital,Seattle,Washington,United States of America.
    In critically ill children, multi-organ-system disease can influence the choice of antiarrhythmic medication. Intravenous therapy is often necessary. There is a scarcity of paediatric critical-care cases demonstrating the dosing, monitoring, and efficacy of intravenous sotalol. Read More

    Intravenous immunoglobulins in children with new onset dilated cardiomyopathy.
    Cardiol Young 2017 Aug 11:1-9. Epub 2017 Aug 11.
    5Department of Pediatric Infectious Diseases,Academic Medical Center,Emma Children's Hospital,Amsterdam,The Netherlands.
    Background: Dilated cardiomyopathy is a rare but serious disorder in children. No effective diagnostic or treatment tools are readily available. This study aimed to evaluate the efficacy of intravenous immunoglobulins in children with new onset dilated cardiomyopathy. Read More

    Cardiovascular pre-participation screening in young athletes: Recommendations of the Association of European Paediatric Cardiology.
    Cardiol Young 2017 Nov 9;27(9):1655-1660. Epub 2017 Aug 9.
    8Merkezi Klinika,Baku,Azerbaijan.
    Sudden death in young competitive athletes can be avoided by implementation of pre-participation screening programmes. A screening programme should be performed only by trained physicians and should include the athlete's personal and family history, physical examination results, and the readings from a 12-lead-electrocardiogram. The athlete should undergo this screening programme every second year to detect progressive diseases. Read More

    Pulmonary vasodilator therapy in tetralogy of Fallot with pulmonary atresia and major aortopulmonary collaterals: case series and review of literature.
    Cardiol Young 2017 Nov 8;27(9):1861-1864. Epub 2017 Aug 8.
    Department of Pediatric Cardiology,Onassis Cardiac Surgery Center,Athens,Greece.
    We present the use of pulmonary vasodilators in three adult patients with unrepaired tetralogy of Fallot, pulmonary atresia, aortopulmonary collaterals, and segmental pulmonary arterial hypertension. Patients improved by 1-2 NYHA classes with modest exercise-tolerance increase, and remained stable without side effects during 2.5, 10, and 14 years. Read More

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