33,372 results match your criteria Cardiology[Journal]


Coronary Subclavian Steal Syndrome: A Contemporary Review.

Cardiology 2020 Jul 10:1-7. Epub 2020 Jul 10.

Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA,

Coronary subclavian steal syndrome (CSSS) is a rare cause of angina. It occurs in patients with prior coronary artery bypass grafting and, specifically, a left internal mammary artery (LIMA) to left anterior descending artery (LAD) graft and co-existent significant subclavian artery stenosis. In this context, there is retrograde blood flow through the LIMA to LAD graft to supply the subclavian artery beyond the significant stenosis. Read More

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http://dx.doi.org/10.1159/000508652DOI Listing

Beginning with the End in Mind - The Case for Primordial and Primary Cardiovascular Prevention in Youth.

Can J Cardiol 2020 Jul 9. Epub 2020 Jul 9.

Department of Pediatrics, Section of Cardiology, University of Colorado School of Medicine, Aurora, Colorado.

Cardiovascular disease (CVD) remains the leading cause of death worldwide. While there is little direct evidence that ties the presence of risk factors in childhood with adult cardiovascular disease, there are multiple indirect lines of evidence that, when synthesized, make a strong case for maintaining cardiovascular health through childhood and adolescence, as well as screening for and treating risk factors when they develop to diminish lifetime risk. This review summarizes these lines of evidence and asserts that it is imperative that primordial and primary cardiovascular risk reduction begin early. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.07.002DOI Listing

Fetal Umbilical Arterial Pulsatility Correlates With 2-Year Growth and Neurodevelopmental Outcomes in Congenital Heart Disease.

Can J Cardiol 2020 Jul 9. Epub 2020 Jul 9.

Fetal & Neonatal Cardiology Program, University of Alberta, Edmonton, Alberta, Canada; Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada. Electronic address:

Background: Children with congenital heart disease (CHD) are at risk of adverse long-term neurodevelopmental outcomes believed in part secondary to prenatal insults. Placental pathology and altered fetal middle cerebral arterial (MCA) flow suggestive of brain sparing have been documented in fetal CHD.

Methods: We included children with d-TGA and HLHS who had a 3 trimester fetal echocardiogram between 2004 and 2014 at which time UA and MCA pulsatility indices (PI) were measured. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.06.024DOI Listing

Deep Learning Applied to Electrocardiogram Interpretation.

Can J Cardiol 2020 Apr 2. Epub 2020 Apr 2.

Alliance for Cardiovascular Diagnostic and Treatment Innovation, Institute of Computational Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1016/j.cjca.2020.03.035DOI Listing

The Sky Is Not Falling: Surgical Perspectives on a New Transcatheter Paradigm.

Can J Cardiol 2020 Mar 19. Epub 2020 Mar 19.

Division of Cardiac Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, Ohio, USA. Electronic address:

The role of cardiac surgeons in the treatment of aortic valve disease is changing with the expansion of transcatheter aortic valve replacement. Recent trials in patients at low surgical risk will further this paradigm shift, and the future cardiac surgeons in this space remain uncertain. In this Viewpoint article, we discuss the role that surgeons can play in the future of structural heart medicine. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.03.016DOI Listing

Yoga for the prevention of cardiovascular disease.

Nat Rev Cardiol 2020 Jul 9. Epub 2020 Jul 9.

Centre for Chronic Disease Control, New Delhi, India.

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http://dx.doi.org/10.1038/s41569-020-0412-xDOI Listing

Searching Novel Approaches to Cardiovascular Risk: Hypertensive Disorders of Pregnancy.

Cardiology 2020 Jul 8:1-4. Epub 2020 Jul 8.

Operative Unit of Cardiology, S. Antonio Abate Hospital, ASP Trapani, Erice, Italy,

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http://dx.doi.org/10.1159/000508651DOI Listing

Rheumatic Fever Licks at the Joints, but Bites at the Heart.

Cardiology 2020 Jul 8:1-4. Epub 2020 Jul 8.

Department of Medicine, Division of Cardiovascular Medicine, The Ohio State University, Columbus, Ohio, USA,

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http://dx.doi.org/10.1159/000508659DOI Listing

Pediatric Dyslipidemia-Beyond Familial Hypercholesterolemia.

Can J Cardiol 2020 Mar 23. Epub 2020 Mar 23.

Departments of Medicine and Biochemistry, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada. Electronic address:

Dyslipidemia is seen with increasing prevalence in young Canadians, mainly mild to moderate hypertriglyceridemia secondary to obesity. This review focuses on pediatric dyslipidemias excluding familial hypercholesterolemia (FH), but including both severe and mild to moderate hypertriglyceridemia, combined hyperlipidemia, and elevated lipoprotein(a) [Lp(a)]. We suggest that for Canadian children and adolescents with dyslipidemia, atherosclerotic cardiovascular disease (ASCVD) risk assessment should include both low-density lipoprotein cholesterol and triglycerides measurement. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.03.020DOI Listing

The GLP-1R Agonist Liraglutide Increases Myocardial Glucose Oxidation Rates via Indirect Mechanisms and Mitigates Experimental Diabetic Cardiomyopathy.

Can J Cardiol 2020 Mar 8. Epub 2020 Mar 8.

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada; Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada; Cardiovascular Research Centre, University of Alberta, Edmonton, Alberta, Canada. Electronic address:

Background: Type 2 diabetes (T2D) increases risk for cardiovascular disease. Of interest, liraglutide, a therapy for T2D that activates the glucagon-like peptide-1 receptor to augment insulin secretion, reduces cardiovascular-related death in people with T2D, though it remains unknown how liraglutide produces these actions. Notably, the glucagon-like peptide-1 receptor is not expressed in ventricular cardiac myocytes, making it likely that ventricular myocardium-independent actions are involved. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.02.098DOI Listing

Coronavirus Disease 2019 (COVID-19) and Cardiac Injury.

JAMA Cardiol 2020 Jul 8. Epub 2020 Jul 8.

Departement of Cardiology, University Hospital of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1001/jamacardio.2020.2453DOI Listing

Late Coronary Stent Thrombosis in a Patient With Coronavirus Disease 2019.

JAMA Cardiol 2020 Jul 8. Epub 2020 Jul 8.

Hospital Universitario de La Princesa, Madrid, Spain.

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http://dx.doi.org/10.1001/jamacardio.2020.2459DOI Listing

Natural History of Asymptomatic Severe Aortic Stenosis and the Association of Early Intervention With Outcomes: A Systematic Review and Meta-Analysis.

JAMA Cardiol 2020 Jul 8. Epub 2020 Jul 8.

Institute of Health Policy, Management and Evaluation, Applied Health Research Centre (AHRC), Li Ka Shing Knowledge Institute of St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

Importance: Whether intervention should be performed in patients with asymptomatic severe aortic stenosis (AS) remains debated.

Objective: To meta-analyze the natural history of asymptomatic severe AS and examine the association of early intervention with survival.

Data Sources: PubMed, Embase, and Cochrane databases were searched from inception to February 1, 2020. Read More

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http://dx.doi.org/10.1001/jamacardio.2020.2497DOI Listing

Life and Death, Hope and Despair in the Era of Coronavirus Disease 2019.

Authors:
Siu-Hin Wan

JAMA Cardiol 2020 Jul 8. Epub 2020 Jul 8.

Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1001/jamacardio.2020.2420DOI Listing

Effect of C-Reactive Protein on Lipoprotein(a)-Associated Cardiovascular Risk in Optimally Treated Patients With High-Risk Vascular Disease: A Prespecified Secondary Analysis of the ACCELERATE Trial.

JAMA Cardiol 2020 Jul 8. Epub 2020 Jul 8.

MonashHeart, Department of Cardiology, Monash University, Clayton, Victoria, Australia.

Importance: Although lipoprotein(a) (Lp[a]) is a causal genetic risk factor for atherosclerotic cardiovascular disease, it remains unclear which patients with established atherosclerotic cardiovascular disease stand to benefit the most from Lp(a) lowering. Whether inflammation can modulate Lp(a)-associated cardiovascular (CV) risk during secondary prevention is unknown.

Objective: To examine whether Lp(a)-associated CV risk is modulated by systemic inflammation in optimally treated patients at high risk of CV disease. Read More

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http://dx.doi.org/10.1001/jamacardio.2020.2413DOI Listing

Coronavirus Disease 2019 (COVID-19) and Cardiac Injury-Reply.

JAMA Cardiol 2020 Jul 8. Epub 2020 Jul 8.

Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.

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http://dx.doi.org/10.1001/jamacardio.2020.2456DOI Listing

Association of Clonal Hematopoiesis of Indeterminate Potential With Inflammatory Gene Expression in Patients With Severe Degenerative Aortic Valve Stenosis or Chronic Postischemic Heart Failure.

JAMA Cardiol 2020 Jul 8. Epub 2020 Jul 8.

Department of Medicine, Cardiology, Goethe University Hospital, Frankfurt, Germany.

Importance: Cytokine release syndrome is a complication of coronavirus disease 2019. Clinically, advanced age and cardiovascular comorbidities are the most important risk factors.

Objective: To determine whether clonal hematopoiesis of indeterminate potential (CHIP), an age-associated condition with excess cardiovascular risk defined as the presence of an expanded, mutated somatic blood cell clone in persons without other hematological abnormalities, may be associated with an inflammatory gene expression sensitizing monocytes to aggravated immune responses. Read More

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http://dx.doi.org/10.1001/jamacardio.2020.2468DOI Listing

Coronavirus Disease 2019 (COVID-19) and Cardiac Injury.

JAMA Cardiol 2020 Jul 8. Epub 2020 Jul 8.

Department of Public Health, Syracuse University, Syracuse, New York.

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http://dx.doi.org/10.1001/jamacardio.2020.2450DOI Listing

Cardiac Damage Staging in Aortic Stenosis: A Perspective From the Cardiac Catheterization Laboratory.

Can J Cardiol 2020 Mar 30. Epub 2020 Mar 30.

Institut universitaire de cardiologie et de pneumologie de Québec-Université Laval/Québec Heart & Lung Institute-Laval University, Québec City, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2020.03.033DOI Listing

Novel Technique for the Treatment of Coronary Artery Perforation.

Can J Cardiol 2020 Mar 20. Epub 2020 Mar 20.

Interventional Cardiology Unit, Rambam Healthcare Campus, Haifa, Israel; Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.

Coronary artery perforation is a rare complication of percutaneous coronary intervention (PCI); its rate is estimated at 0.4- 0.7% of all PCIs. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.03.017DOI Listing

Understanding Outcomes of Dialysis Patients Undergoing Transcatheter Aortic Valve Implantation.

Authors:
Daniel J P Burns

Can J Cardiol 2020 Mar 31. Epub 2020 Mar 31.

Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2020.03.036DOI Listing

Chronic Persistence of Hemorrhage, Microvascular Obstruction, and Edema After Myocardial Infarction: Utility of Cardiac Magnetic Resonance Imaging.

Can J Cardiol 2020 Apr 6. Epub 2020 Apr 6.

Schulich Heart Program, Sunnybrook Research Institute, xxx; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2020.03.045DOI Listing

Beta-Blocker Therapy After Myocardial Infarction: Is There an Expiry Date?

Can J Cardiol 2020 Apr 11. Epub 2020 Apr 11.

Leon H. Charney Division of Cardiology, Department of Medicine, New York University Grossman School of Medicine, New York, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2020.04.007DOI Listing

Dapagliflozin reduces left ventricular mass.

Authors:
Gregory B Lim

Nat Rev Cardiol 2020 Jul 6. Epub 2020 Jul 6.

Nature Reviews Cardiology, .

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http://dx.doi.org/10.1038/s41569-020-0417-5DOI Listing

Benefit of dapagliflozin is independent of LVEF.

Authors:
Gregory B Lim

Nat Rev Cardiol 2020 Jul 6. Epub 2020 Jul 6.

Nature Reviews Cardiology, .

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http://dx.doi.org/10.1038/s41569-020-0419-3DOI Listing

Myosin activator improves cardiac function.

Authors:
Gregory B Lim

Nat Rev Cardiol 2020 Jul 6. Epub 2020 Jul 6.

Nature Reviews Cardiology, .

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http://dx.doi.org/10.1038/s41569-020-0418-4DOI Listing

Notes From Cardiology Clinic: Health Care Heroine, Unpaid and Unappreciated.

Authors:
David D Waters

Can J Cardiol 2020 Jun 5. Epub 2020 Jun 5.

Division of Cardiology, Zuckerberg San Francisco General Hospital, and Department of Medicine, University of California, San Francisco, California, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2020.04.028DOI Listing

Links between Child and Adolescent Psychiatric Disorders and Cardiovascular Risk.

Can J Cardiol 2020 Jul 3. Epub 2020 Jul 3.

Department of Psychiatry, Hospital for Sick Children Department of Psychiatry, Faculty of Medicine, University of Toronto.

This narrative review, emphasizing children and adolescents, addresses the link between five psychiatric disorders and cardiovascular risk: attention deficit hyperactivity disorder (ADHD), autism spectrum disorders, anxiety disorders, depression, and bipolar disorders. The evidence regarding cardiovascular risk factors, non-invasive measures of early atherosclerosis, and cardiovascular disease prevalence and/or mortality is summarized. Whereas multiple studies have examined stimulant treatment of ADHD in relation to cardiovascular death, and autonomic-vagal function in autism spectrum disorders, little is known regarding atherosclerotic cardiovascular disease in these conditions. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.06.023DOI Listing

Primary aldosteronism in hypertension: more than a factoid.

Can J Cardiol 2020 Jul 3. Epub 2020 Jul 3.

Department of Medicine and Robarts Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.1016/j.cjca.2020.06.022DOI Listing

The Rise of Open-Sourced Machine Learning in Small and Imbalanced Datasets: Predicting In-Stent Restenosis.

Can J Cardiol 2020 Feb 8. Epub 2020 Feb 8.

Division of Cardiology and Cardiovascular Research Institute, Cardiology, Department of Medicine, University of California, San Francisco, California, USA; Bakar Computational Health Sciences Institute, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1016/j.cjca.2020.02.002DOI Listing
February 2020

Canadian Cardiovascular Society Clinical Practice Update on the Assessment and Management of Syncope.

Can J Cardiol 2020 Jul 2. Epub 2020 Jul 2.

Department of Emergency Medicine, Queen's University, Kingston, Ontario, Canada.

Syncope is a symptom that occurs in multiple settings and has a variety of underlying causes, ranging from benign to life threatening. Determining the underlying diagnosis and prognosis can be challenging and often results in an unstructured approach to evaluation, which is ineffective and costly. In this first ever document, the Canadian Cardiovascular Society (CCS) provides a clinical practice update on the assessment and management of syncope. Read More

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http://dx.doi.org/10.1016/j.cjca.2019.12.023DOI Listing

Quadriceps strength and mortality in older patients with heart failure.

Can J Cardiol 2020 Jul 2. Epub 2020 Jul 2.

Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.

Background: This study was performed to test the hypothesis that low quadriceps isometric strength (QIS) were associated with greater risk of mortality and have the additive prognostic significance to heart failure (HF) severity and gait speed in older patients with heart failure.

Methods: A retrospective cohort study was performed in 1273 patients ≥60 years old with HF (mean age 75 ± 8 years, 59.1% men), in all of whom usual gait speed and maximal QIS had been evaluated during hospitalization. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.06.019DOI Listing

Childhood obesity and cardiovascular disease risk: working towards solutions.

Can J Cardiol 2020 Jul 2. Epub 2020 Jul 2.

Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada; Centre for Metabolism, Obesity, and Diabetes Research, McMaster University, Hamilton, Ontario, Canada. Electronic address:

The prevalence of obesity in childhood is high and continues to increase globally. It is currently estimated that 381 million children worldwide have overweight or obesity. This disease stems from multiple, complex pathways that can present early in life. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.06.020DOI Listing

Comparison of 1-Year Pre- and Post-Transcatheter Aortic Valve Replacement Hospitalization Rates: A Population-Based Cohort Study.

Can J Cardiol 2020 Jan 20. Epub 2020 Jan 20.

Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.

Background: Rehospitalization rates post-transcatheter aortic valve replacement (TAVR) are high; however, it is not known how these compare with pre-TAVR hospitalization rates. Our objective was to determine the association between the index TAVR and hospitalization rates pre- and postprocedure.

Methods: A retrospective observational study was performed including all TAVR procedures performed in Ontario, Canada, between 2013 and 2017. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.01.009DOI Listing
January 2020

Prenatal Diagnosis of Transposition of the Great Arteries Reduces Postnatal Mortality: A Population-Based Study.

Can J Cardiol 2020 Jan 20. Epub 2020 Jan 20.

The Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address:

Background: Transposition of the great arteries (TGA) may present as a life-threatening neonatal malformation. Although prenatal detection facilitates the perinatal management, the impact on outcome is controversial.

Methods: This study reviewed the differences in prenatal diagnosis of TGA from 2009 to 2014 among the 5 geographic areas in Ontario and compared the management, morbidity, and mortality among neonates with a prenatal (prenatal cohort; n = 70) vs a postnatal (postnatal cohort; n = 76) anomaly diagnosis. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.01.010DOI Listing
January 2020

The Changing Epidemiology of Cardiovascular Disease: Two Steps Forward, One Step Back.

Authors:
Daniel G Hackam

Can J Cardiol 2020 Jun 18. Epub 2020 Jun 18.

Division of Clinical Pharmacology, Departments of Medicine, Clinical Neurological Sciences, and Epidemiology and Biostatistics, Western University, London, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2020.03.010DOI Listing

Recent Trends in Hospitalizations for Cardiovascular Disease, Stroke, and Vascular Cognitive Impairment in Canada.

Can J Cardiol 2020 Jun 18. Epub 2020 Jun 18.

Heart and Stroke Foundation of Canada, Toronto, Ontario, Canada. Electronic address:

Background: We analyzed hospitalization rates for a broad set of cardiovascular diseases, stroke, and vascular cognitive impairment (VCI) between 2007 and 2016 in Canada to characterize population-level trends and demographic and provincial/territorial variation in inpatient health care utilization.

Methods: Record-level administrative hospitalization data from April 1, 2007 to March 31, 2017 for individuals aged 0-105 years were obtained from the Canadian Institute for Health Information Discharge Abstract Database. Data were available for all provinces and territories, except Quebec. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.03.007DOI Listing

Closer to the Heart: Incentivizing Improved Care and Outcomes for Patients with Heart Failure.

Can J Cardiol 2020 Jul 1. Epub 2020 Jul 1.

Department of Medicine, University of Toronto, Toronto, ON, Canada; Institute for Clinical Evaluative Sciences (ICES), Toronto and Ottawa, ON, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; Department of Medicine, Sinai Health System, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.cjca.2020.06.018DOI Listing

Is the Die Cast by Surgeon's Choice or Patient's Anatomy? Late Outcomes in Tetralogy of Fallot.

Can J Cardiol 2020 Apr 1. Epub 2020 Apr 1.

University of Texas Southwestern, Children's Health Dallas, Dallas, Texas, USA.

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http://dx.doi.org/10.1016/j.cjca.2020.03.039DOI Listing

The Yield of Routine Cardiac Imaging in Breast Cancer Patients Receiving Trastuzumab-based Treatment: A Retrospective Cohort Study.

Can J Cardiol 2019 Dec 28. Epub 2019 Dec 28.

Women's College Hospital (WCH), Toronto, Ontario, Canada; Ted Rogers Program in Cardiotoxicity Prevention, Division of Cardiology, Peter Munk Cardiac Center, University Health Network, Toronto, Ontario, Canada; Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, Ontario, Canada; WCH Institute for Health Systems Solutions and Virtual Care, Toronto, Ontario, Canada. Electronic address:

Background: There are limited data on the yield of routine cardiac imaging for trastuzumab-treated patients with breast cancer.

Methods: We conducted a retrospective cohort study of patients with breast cancer treated with adjuvant trastuzumab between 2007 and 2012 at Princess Margaret Cancer Centre (Toronto, Canada). We classified imaging tests as clinically prompted or routinely ordered and determined whether each test led to changes in patient care. Read More

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http://dx.doi.org/10.1016/j.cjca.2019.12.021DOI Listing
December 2019

Examining Coronary Revascularization Practice Patterns for Diabetics: Perceived Barriers, Facilitators, and Implications for Knowledge Translation.

Can J Cardiol 2019 Nov 27. Epub 2019 Nov 27.

British Columbia Centre for Improved Cardiovascular Health, Vancouver, British Columbia, Canada; Division of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada.

Background: The FREEDOM trial provided robust evidence that coronary artery bypass grafting (CABG) was superior to percutaneous coronary intervention (PCI) for coronary revascularization in patients with diabetes mellitus (DM) and multivessel coronary artery disease (MV-CAD). The present study examined practice pattern changes and perceived barriers and facilitators to implementing FREEDOM trial evidence in British Columbia (BC).

Methods: Using a population-based database of cardiac procedures in BC, PCI:CABG ratios from 2007-2014 were compared before and after publication of the FREEDOM trial in the 4 tertiary cardiac centres that provided both CABG and PCI. Read More

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http://dx.doi.org/10.1016/j.cjca.2019.11.026DOI Listing
November 2019

Interleukin-9 Aggravates Isoproterenol-Induced Heart Failure by Activating Signal Transducer and Activator of Transcription 3 Signalling.

Can J Cardiol 2020 Jan 24. Epub 2020 Jan 24.

Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China. Electronic address:

Background: Previous studies have demonstrated that inflammation is closely related to the occurrence and development of heart failure (HF). As an inflammation-related cytokine, interleukin (IL)-9 has been reported to be involved in the development of cardiovascular diseases. However, the role of IL-9 in HF in response to isoproterenol (ISO) stimulation has barely been explored. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.01.011DOI Listing
January 2020

Low-Molecular-Weight Heparin vs Warfarin for Thromboprophylaxis in Children with Coronary Artery Aneurysms After Kawasaki Disease: A Pragmatic Registry Trial.

Can J Cardiol 2020 Jul 1. Epub 2020 Jul 1.

Division of Cardiology, Department of Pediatrics, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address:

Background: The substantial risk of thrombosis in large coronary artery aneurysms (CAAs) (maximum z-score ≥ 10) after Kawasaki disease (KD) mandates effective thromboprophylaxis. We sought to determine the effectiveness of anticoagulation (low-molecular-weight heparin [LMWH] or warfarin) for thromboprophylaxis in large CAAs.

Methods: Data from 383 patients enrolled in the International KD Registry (IKDR) were used. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.01.016DOI Listing

Myocardial ischaemia-reperfusion injury and cardioprotection in perspective.

Authors:
Gerd Heusch

Nat Rev Cardiol 2020 Jul 3. Epub 2020 Jul 3.

Institute for Pathophysiology, West German Heart and Vascular Center, University of Duisburg-Essen, Essen, Germany.

Despite the increasing use and success of interventional coronary reperfusion strategies, morbidity and mortality from acute myocardial infarction are still substantial. Myocardial infarct size is a major determinant of prognosis in these patients. Therefore, cardioprotective strategies aim to reduce infarct size. Read More

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http://dx.doi.org/10.1038/s41569-020-0403-yDOI Listing

Sex Differences in Cardiac Resynchronization Therapy Device Implantations and Complications: Tough Questions, Tougher Answers.

Authors:
F Daniel Ramirez

Can J Cardiol 2020 Mar 23. Epub 2020 Mar 23.

Hôpital Cardiologique du Haut Lévêque, CHU Bordeaux, and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque), Bordeaux-Pessac, France. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2020.03.019DOI Listing

Altering Dementia Risk: Can Fitness Overcome Obesity in Relation to Cognition?

Can J Cardiol 2020 Mar 12. Epub 2020 Mar 12.

Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2020.03.008DOI Listing

Interpreting Administrative Data About Transcatheter Aortic Valve Replacement Effects on Hospitalisation Outcomes: The Devil's in the Details.

Can J Cardiol 2020 Apr 14. Epub 2020 Apr 14.

Institut de Cardiologie de Montréal, Department of Cardiology, Université de Montréal, Montréal, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2020.03.050DOI Listing

Precision Medicine in TAVR: How to Select the Right Device for the Right Patient.

Can J Cardiol 2020 Apr 6. Epub 2020 Apr 6.

Sorbonne University, ACTION Group, INSERM UMRS 1166, Institut de Cardiologie, Hôpital Pitié-Salpêtrière, Paris, France.

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http://dx.doi.org/10.1016/j.cjca.2020.03.043DOI Listing

Obese but Fit: The Benefits of Fitness on Cognition in Obese Older Adults.

Can J Cardiol 2020 Jan 16. Epub 2020 Jan 16.

Centre de médecine préventive et d'activité physique (Centre ÉPIC), Montreal Heart Institute, Université de Montréal, Montréal, Québec, Canada; Research Center, Montreal Heart Institute, Université de Montréal, Montréal, Québec, Canada; Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, Québec, Canada. Electronic address:

Background: Obesity is associated with an accelerated cognitive decline. Aerobic fitness has a protective effect on cognition in older adults, but no study has investigated this effect in obese individuals. The present study aimed to 1) compare cognitive function in lower-fit (LoFit) and higher-fit (HiFit) obese individuals compared with nonobese individuals, and 2) examine the association between exercise variables (including hemodynamic variables) and cognitive function in obese individuals. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.01.005DOI Listing
January 2020