31,656 results match your criteria Cardiology[Journal]


Inhibition of sodium-glucose cotransporter-2 preserves cardiac function during regional myocardial ischemia independent of alterations in myocardial substrate utilization.

Basic Res Cardiol 2019 Apr 19;114(3):25. Epub 2019 Apr 19.

Department of Cellular and Integrative Physiology, Indiana University School of Medicine, 635 Barnhill Drive, Indianapolis, IN, 46202, USA.

The goal of the present study was to evaluate the effects of SGLT2i on cardiac contractile function, substrate utilization, and efficiency before and during regional myocardial ischemia/reperfusion injury in normal, metabolically healthy swine. Lean swine received placebo or canagliflozin (300 mg PO) 24 h prior to and the morning of an invasive physiologic study protocol. Hemodynamic and cardiac function measurements were obtained at baseline, during a 30-min complete occlusion of the circumflex coronary artery, and during a 2-h reperfusion period. Read More

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http://link.springer.com/10.1007/s00395-019-0733-2
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http://dx.doi.org/10.1007/s00395-019-0733-2DOI Listing
April 2019
1 Read

[Intracardiac and Pulmonary Cement Embolism after Percutaneous Vertebroplasty].

Kardiologiia 2019 Apr 18;59(4):92-96. Epub 2019 Apr 18.

Central Clinical Hospital of the Management Affair of President RF, Moscow.

The article presents a clinical case of embolism with bone cement of the right ventricle of the heart and pulmonary artery after percutaneous vertebroplasty in a patient aged 63 years. According to the results of a comprehensive examination using ultrasound and x-ray methods, three foreign bodies were found: in the right ventricle cavity, in the trunk of the pulmonary artery, in the branches of the left pulmonary artery. Considering the stable condition, normal blood oxygen saturation, the lack of influence of formations on intracardiac hemodynamics, it was decided to refrain from surgery, since the risk of intervention exceeded the possible benefit. Read More

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http://dx.doi.org/10.18087/cardio.2019.4.10255DOI Listing

[Macrophages and Their Role in Destabilization of an Atherosclerotic Plaque].

Kardiologiia 2019 Apr 17;59(4):88-91. Epub 2019 Apr 17.

Institute of Experimental Medicine, St. Petersburg.

The modern data on structure and the functional activity of macrophages are presented in the review. It is shown that they are the nonhomogeneous cell population. Two of their main subpopulations are presented as M1 and M2 phenotypes which perform opposite functions at inflammation development. Read More

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https://lib.ossn.ru/jour/article/view/597
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http://dx.doi.org/10.18087/cardio.2019.4.10254DOI Listing
April 2019
1 Read

[Type 2 Diabetes Mellitus and Heart Failure: Innovative Possibilities for Management of Prognosis].

Kardiologiia 2019 Apr 17;59(4):76-87. Epub 2019 Apr 17.

Peoples Friendship University of Russia (RUDN University).

Type 2 diabetes mellitus (T2DM) has gone beyond the professional interests of one specialty. T2DM, cardiovascular (CV) diseases and chronic kidney disease, considered from the standpoint of a single cardio-reno-metabolic continuum, place a heavy economic burden on society. At the same time, the improvement of diagnostic methods and medical technologies led to distinct decrease in the frequency and mortality from a number of complications of T2DM, including myocardial infarction and stroke, but other states took their place. Read More

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https://lib.ossn.ru/jour/article/view/596
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http://dx.doi.org/10.18087/cardio.2019.4.10253DOI Listing
April 2019
2 Reads

[Paleev Nikolai Romanovich (to the 90th birthday)].

Kardiologiia 2019 Apr 17;59(4):74-75. Epub 2019 Apr 17.

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[Myocardial Contractile Function in Patients with Liver Cirrhosis and Syndrome of Bacterial Overgrowth Syndrome].

Kardiologiia 2019 Apr 17;59(4):67-73. Epub 2019 Apr 17.

Sechenov First Moscow State Medical University (Sechenov University).

Objective: to study myocardial contractile function in patients with liver cirrhosis and ascites in the presence of bacterial overgrowth syndrome (BOS) and pathological bacterial translocation.

Materials And Methods: We included in this study 59 patients with Child-Pugh class B and C liver cirrhosis (LC) of various etiology and ascites. Control group comprised 12 patients with ischemic heart disease complicated by chronic heart failure (CHF). Read More

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http://dx.doi.org/10.18087/cardio.2019.4.10252DOI Listing
April 2019
2 Reads

[The Role of Endothelial Dysfunction in the Development of Cardiotoxic Action of Cytostatics in Patients with Lymphoproliferative Diseases].

Kardiologiia 2019 Apr 17;59(4):64-66. Epub 2019 Apr 17.

Sechenov First Moscow State Medical University (Sechenov University).

Understanding mechanisms of chemotherapy cardiotoxicity is an important problem due to the lack of clear understanding of its occurrence. Development of endothelial dysfunction is considered to be one of possible ways in implementation of these side effects. The analysis of endothelin-1 and e-selectin levels in 26  patients with lymphoproliferative diseases before and after the completion of the treatment program was been performed. Read More

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http://dx.doi.org/10.18087/cardio.2019.4.10251DOI Listing

[Non-Central Influences of α2-Adrenergic and Imidazoline Agonist Interactions in Isolated ardiomyocytes Cardiac Cells].

Kardiologiia 2019 Apr 17;59(4):52-63. Epub 2019 Apr 17.

Institute of Theoretical and Experimental Biophysics, Pushchino.

Aim: to investigate the functional interaction of α2-adrenergic and imidazoline receptors recently identified on the sarcolemma of isolated cardiomyocytes for regulation of the intracellular calcium and the production of the signal molecule of nitric oxide (NO).

Materials And Methods: experiments were performed on isolated left ventricular cardiomyocytes of Wistar rats. Potential-dependent Ca2+-currents were measured from the whole-cell by the patch-clamp method in "perforated-patch" configuration. Read More

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https://lib.ossn.ru/jour/article/view/591
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http://dx.doi.org/10.18087/cardio.2019.4.10241DOI Listing
April 2019
1 Read

[Pressure and Volume Characteristics of the Left Ventriclе in Its Diastolic and Systolic Dysfunction].

Kardiologiia 2019 Apr 17;59(4):45-51. Epub 2019 Apr 17.

National Medical Research Centre of Cardiology, Moscow.

The Aim of the study was a detailed investigation of pressure volume-loop (PV-loop) curves in the rat heart during development of doxorubicin cardiomyopathy.

Materials And Methods: Cardiomyopathy in rats has been developed after 4 weeks doxorubicin administration (2 mg / kg weekly).

Results: Echocardiographic study of rats in 8 weeks from onset of doxorubicin administration showed preponderance of systolic dysfunction (67 %) with decrease of left ventricular (LV) ejection fraction (EF) by 30 %. Read More

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http://dx.doi.org/10.18087/cardio.2019.4.2647DOI Listing

[Decreased Heart Rate Variability in Sickle Cell Anemia as Effect of Pulmonary Arterial Hypertension].

Kardiologiia 2019 Apr 17;59(4):39-44. Epub 2019 Apr 17.

Central State Medical Academy, President Management Department RF.

Decreased heart rate variability (HRV) is associated with increased mortality risk in various diseases. The objective of this investigation:to study HRV in patients with sickle cell anemia (SCA) and to assess the effect of pulmonary arterial hypertension (PAH) on HRV in these patients. Materials and methods. Read More

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http://dx.doi.org/10.18087/cardio.2019.4.10237DOI Listing

[Visualisation and Radiofrequency Ablation of Sympathetic Innervation Loci in the Left Atrium in Patients with Paroxysmal Atrial Fibrillation].

Kardiologiia 2019 Apr 16;59(4):33-38. Epub 2019 Apr 16.

National Medical Research Center named after acad. E. N. Meshalkin, Novosibirsk.

Introduction: A novel cardiac gamma camera utilizes the radiopharmaceutical Iodine-123-Meta-iodobenzylguanidine (123I-MIBG) to visualize cardiac sympathetic innervation. Physiological accumulation of 123I-mIBG provides an anatomical quantitative determination of the structures of the autonomic nervous system (ANS) with discrete uptake areas (DUA) of sympathetic activity located in the left atrium (LA) corresponding to the main ganglionic plexi (GP) clusters that could not previously be visualized.

Aim: to visualize the DUA of the heart in patients with paroxysmal atrial fibrillation (AF) and to assess the effect of radiofrequency ablation (RFA) on DUA in LA. Read More

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http://dx.doi.org/10.18087/cardio.2019.4.10249DOI Listing
April 2019
1 Read

[Progression of Chronic Heart Failure: Prognostic Criteria and Non-Drug Prevention].

Kardiologiia 2019 Apr 16;59(4):26-32. Epub 2019 Apr 16.

Republic Scientific and Practical Center "Cardiology", Minsk.

Purpose: to study frequency of progression of chronic heart failure (CHF), to develop multifactorial models for evaluation of risk of progression, and measures of non-drug secondary prevention of CHF.

Materials And Methods: We included in this study 531 patients with functional class (FC) I-III CHF (FC I - n=254, FC II - n=255, FC III - n=22). Examination included clinical-instrumental, clinical-functional, and laboratory (with determination of NT-proBNP concentration) investigations, use of the AUDIT and Morisky Green questionnaires. Read More

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https://lib.ossn.ru/jour/article/view/587
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http://dx.doi.org/10.18087/cardio.2019.4.10248DOI Listing
April 2019
2 Reads

[Selection of Patients with Resistant Arterial Hypertension for the Catheter-Based Renal Sympathetic Denervation].

Kardiologiia 2019 Apr 16;59(4):21-25. Epub 2019 Apr 16.

Samara State Medical University.

Purpose: elaboration of algorithm for selection of patients with resistant arterial hypertension (AH) for Catheter-Based Renal Sympathetic Denervation (CBRSD).

Materials And Methods: We examined 284 patients with resistant AH. On stage 1 we excluded most frequent causes of secondary AH. Read More

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http://dx.doi.org/10.18087/cardio.2019.4.10234DOI Listing

[Dynamics of Coronary Calcification and Its Association with the Clinical Course of Ischemic Heart Disease and Osteopenic Syndrome].

Kardiologiia 2019 Apr 16;59(4):12-20. Epub 2019 Apr 16.

Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo Kemerovo State Medical University.

Purpose: to study the relationship between degree of calcification of coronary arteries, osteopenic syndrome, and clinical course of ischemic heart disease (IHD) during 3-5 years of follow-up in men after coronary artery bypass grafting (CABG). Materials and methods. We included in this prospective study 111 men admitted for CABG under cardiopulmonary bypass. Read More

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https://lib.ossn.ru/jour/article/view/584
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http://dx.doi.org/10.18087/cardio.2019.4.10247DOI Listing
April 2019
3 Reads

[Association of Strategy of Direct Stenting of Infarct-Related Artery with Reduction of Mortality in Woman with ST-Elevation Myocardial Infarction].

Kardiologiia 2019 Apr 16;59(4):5-11. Epub 2019 Apr 16.

Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Sciences.

Aim of this study was to evaluate the impact of direct stenting (DS) strategy on the results of treatment of female patients with STelevation myocardial infarction (STEMI) undergoing percutaneous coronary interventions (PCIs).

Materials And Methods: Among 1297 patients with STEMI admitted to the coronary care unit and subjected to PCIs from 2006 to 2015 there were 330 women (25.4 %). Read More

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http://dx.doi.org/10.18087/cardio.2019.4.10246DOI Listing

Seasonality in Mortality in a Cardiology Department: A Five-Year Analysis in 500 Patients.

Cardiology 2019 Apr 18;142(2):67-72. Epub 2019 Apr 18.

Servicio de Cardiología, Hospital Universitario Gregorio Marañón, CIBERCV, Madrid, Spain,

Background: Previous studies have indicated that cardiovascular mortality follows a seasonal trend. The aim of this work was to determine the evolution of mortality throughout the year in a cardiology department.

Methods: All admissions and deaths occurring in our Cardiology Department over a 5-year period (2013-2017) were recorded retrospectively. Read More

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https://www.karger.com/Article/FullText/497815
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http://dx.doi.org/10.1159/000497815DOI Listing
April 2019
6 Reads

Sex Influence on the Efficacy and Safety of Sacubitril/Valsartan.

Cardiology 2019 Apr 18;142(2):73-78. Epub 2019 Apr 18.

Servicio de Cardiología, Hospital Universitario Gregorio Marañón, CIBERCV, Madrid, Spain,

Background: Women are underrepresented in sacubitril/valsartan (SV) clinical trials. The aim of this study was to assess sex-specific differences in efficacy, tolerability, and safety of SV in real-world heart failure with reduced ejection fraction (HFrEF) patients.

Methods: A prospective registry in 10 centers including all patients who started SV during the last 6 months was analyzed in this study. Read More

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https://www.karger.com/Article/FullText/498984
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http://dx.doi.org/10.1159/000498984DOI Listing
April 2019
1 Read

Medical Misinformation: Vet the Message!

Authors:
Joseph A Hill

Cardiology 2019 Apr 18;142(2):63-65. Epub 2019 Apr 18.

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA,

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https://www.karger.com/Article/FullText/497263
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http://dx.doi.org/10.1159/000497263DOI Listing
April 2019
1 Read

What Is a Better Procedural Methodology for Endomyocardial Biopsy.

Authors:
Teruhiko Imamura

Cardiology 2019 Apr 18;142(2):66. Epub 2019 Apr 18.

Division of Cardiology, University of Chicago Medical Center, Chicago, Illinois, USA,

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http://dx.doi.org/10.1159/000499340DOI Listing

Postconditioning with Lactate-Enriched Blood in Patients with ST-Segment Elevation Myocardial Infarction.

Authors:
Takashi Koyama

Cardiology 2019 Apr 18;142(2):79-80. Epub 2019 Apr 18.

Department of Cardiology, Saitama Municipal Hospital, Saitama City, Japan,

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http://dx.doi.org/10.1159/000499036DOI Listing

JAMA Cardiology.

Authors:

JAMA Cardiol 2019 Apr;4(4):306

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http://dx.doi.org/10.1001/jamacardio.2018.3191DOI Listing

Effect of a Quality of Care Improvement Initiative in Patients With Acute Coronary Syndrome in Resource-Constrained Hospitals in China: A Randomized Clinical Trial.

JAMA Cardiol 2019 Apr 17. Epub 2019 Apr 17.

Department of Cardiology, Cardiovascular Institute and Fuwai Hospital, Beijing, China.

Importance: Prior observational studies suggest that quality of care improvement (QCI) initiatives can improve the clinical outcomes of acute coronary syndrome (ACS). To our knowledge, this has never been demonstrated in a well-powered randomized clinical trial.

Objective: To determine whether a clinical pathway-based, multifaceted QCI intervention could improve clinical outcomes among patients with ACS in resource-constrained hospitals in China. Read More

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http://dx.doi.org/10.1001/jamacardio.2019.0897DOI Listing
April 2019
2 Reads

Anatomic Relationship of the Complex Tricuspid Valve, Right Ventricle, and Pulmonary Vasculature: A Review.

JAMA Cardiol 2019 Apr 17. Epub 2019 Apr 17.

CARIM School for Cardiovascular Diseases, Maastricht University Medical Center/Maastricht University, Maastricht, the Netherlands.

Importance: Severe functional or secondary tricuspid regurgitation (TR) is associated with poor long-term outcomes in natural history studies as well as specific disease states. An understanding of the physiologic causes of the TR is lacking precluding a systematic approach to treatment.

Observations: The complex anatomic relationship between the tricuspid valve apparatus and structure of the right side of the heart lends insight into the functional changes seen with secondary TR. Read More

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http://dx.doi.org/10.1001/jamacardio.2019.0535DOI Listing
April 2019
1 Read

Facilitating Conversion of Implantable Cardioverter-Defibrillator Therapy to Pacing Only-Time to Adapt.

JAMA Cardiol 2019 Apr 17. Epub 2019 Apr 17.

The Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamacardio.2019.0882DOI Listing

Targeting ATP citrate lyase to reduce LDL cholesterol.

Authors:
Karina Huynh

Nat Rev Cardiol 2019 Apr 16. Epub 2019 Apr 16.

Nature Reviews Cardiology, .

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http://dx.doi.org/10.1038/s41569-019-0201-6DOI Listing
April 2019
1 Read

[Predictors for development of major cardiovascular events in elderly patients with severe and extremely severe chronic obstructive pulmonary disease in combination with early stages of chronic kidney disease].

Kardiologiia 2019 Apr 13;59(3S):52-60. Epub 2019 Apr 13.

State Budgetary Institution of Health Care, Territorial Clinical Hospital #2, Krasnykh Partizan 6, k. 2, Krasnodar, Russia 350012.

Aim: To study the structure of major cardiovascular events (MCVE) and to identify their independent predictors in elderly patients with severe and extremely severe chronic obstructive pulmonary disease (COPD) in combination with early stages of chronic kidney disease (CKD).

Materials And Methods: The study included 172 elderly patients with stage 3-4 COPD associated with stage 1-2 CKD. Initially, risk factors for MCVE were identified and levels of vitamin D (25 (ОН) D) were measured for all patients. Read More

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http://dx.doi.org/10.18087/cardio.2539DOI Listing
April 2019
3 Reads

[Predictors for development of major cardiovascular events in elderly patients with severe and extremely severe chronic obstructive pulmonary disease in combination with early stages of chronic kidney disease].

Kardiologiia 2019 Apr 13;59(3S):43-51. Epub 2019 Apr 13.

Privolzhsky Research Medical University, Minin and Pozharsky square 10/1, Nizhny Novgorod 603950.

The aim of the study was to evaluate efficacy, safety and treatment compliance for different ASA forms (Aspirin Cardio, Cardiomagnyl and Trombo Ass) in a 6-month study.

Materials And Methods: A prospective 6-month open, comparative study originally included 600 patients with IHD and stable angina who received chronic therapy with different forms of aspirin. In the prospective part of the study, these patients were subdivided into four groups: group 1 consisted of 200 patients switched to Aspirin Cardio; group 2 - 200 pa - tients receiving chronic therapy with this drug; group 3 - 100 patients continuing on the Trombo Ass treatment; and group 4 - 100 pa - tients who had been treated with Cardiomagnyl for a long time. Read More

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http://dx.doi.org/10.18087/cardio.2536DOI Listing
April 2019
1 Read

[Automatic detection of ventricular and supraventricular wide QRS arrhythmias using complex of morphological criteria and algorithms].

Kardiologiia 2019 Apr 13;59(3S):36-42. Epub 2019 Apr 13.

Institute of Cardiological Technics (INCART), Vyborg highway, 22A, St. Petersburg 194214; Scientific, Clinical and Educational Cardiology Center, University Embankment 7-9, St. Petersburg 194214.

Aim: The aim of study is a detection of ventricular and supraventricular wide QRS arrhythmias using complex of morphological criteria and algorithms by method of automatic analysis.

Materials And Methods: For 100 patients (m/f - 61/39, Me (min; max) - 44.5 (10; 85) years) of researched group the analysis of 14306 single wide ectopic complexes (QRS 120-230 ms) has been done. Read More

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http://dx.doi.org/10.18087/cardio.2659DOI Listing
April 2019
2 Reads

[Blood lipids and angina pectoris (by epidemiological cardiological Rose questionnaire) in the population of 25-45 years of Novosibirsk].

Kardiologiia 2019 Apr 13;59(3S):30-35. Epub 2019 Apr 13.

Research Institute of Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (IIPM - Branch of IC G SB RAS); B. Bogatkov Str., 175/1, Novosibirsk, 630089, Russian Federation.

The aim of the study was to investigate the prevalence of angina pectoris (AP) according to the standardized epidemiological questionnaire of Rose in the population of 25-45 years of Novosibirsk and to identify its association with some lipid and non-lipid risk factors for coronary heart disease (CHD).

Material And Methods: Cross-sectional survey of the population aged 25-45 in Novosibirsk was carried out. The study included 1439 people (656 men and 783 women). Read More

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http://dx.doi.org/10.18087/cardio.2600DOI Listing
April 2019
1 Read

[Circadian rhythms of thyroid hormones in patients with ischemic heart disease, arterial hypertension, and atrial fibrillation].

Kardiologiia 2019 Apr 13;59(3S):23-29. Epub 2019 Apr 13.

V.I. Razumovsky Saratov State Medical University, Bolshaya Kazachjya 112, Saratov 410012.

Aim: To evaluate the interrelationship between diurnal changes in thyrotropic hormone (TTH), free triiodothyronine (FT3), and clinical features of IHD in combination with AH and atrial fibrillation (AF).

Materials And Methods: Levels of TTH, FT3, and plasma cortisol were measured in 133 patients with IHD and AH with or without paroxysmal AF. The studied indexes included duration of IHD, AH, and AF; presence or absence of AF and AH; incidence rate of AF episodes per week; severity of exertional angina; systolic and diastolic BP; and EchoCG data. Read More

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http://dx.doi.org/10.18087/cardio.2506DOI Listing
April 2019
1 Read

[Impact of Diabetes Mellitus and blood glucose levels on the results of treatment of patients with ST-elevation myocardial infarction undergoing percutaneous coronary interventions].

Kardiologiia 2019 Apr 13;59(3S):16-22. Epub 2019 Apr 13.

"Tyumen Cardiology Research Center", Branch of the Federal State Budgetary Science Institution "Tomsk National Research Medical Center of the Russian Academy of Sciences", Melnikayte 111, Tyumen 625026.

The aim of this study was to evaluate the impact of diabetes mellitus (DM) and glucose levels on the results of treatment of patients with ST-elevation myocardial infarction (STEMI) undergoing percutaneous coronary interventions (PCIs).

Materials And Methods: Data were collected from all patients (n=1280) with STEMI who were admitted to the coronary care unit and underwent PCIs from 2006 to 2015. 212 (16. Read More

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http://dx.doi.org/10.18087/cardio.2520DOI Listing
April 2019
1 Read

[Possibilities of estimation of breast cancer targeted therapy cardiotoxicity in routine clinical practice].

Kardiologiia 2019 Apr 13;59(3S):10-15. Epub 2019 Apr 13.

Kursk State Medical University (KSMU), K. Marx st., 3, Kursk 305041, Russia.

Aims: To estimate cardiotoxicity of targeted therapy of breast cancer by the results of methods of investigation, which are used in routine clinical practice.

Methods And Results: We have made a retrospective analysis of medical documentation of patients with breast cancer, which are given trastuzumab in mono regimen and as a part of antitumor chemotherapy. An average number of chemotherapy's courses is 10,3±1,9. Read More

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http://dx.doi.org/10.18087/cardio.2550DOI Listing

[Evaluation of endothelial dysfunction and the possibility of its correction at the present stage in patients with cardiovascular diseases].

Kardiologiia 2019 Apr 13;59(3S):4-9. Epub 2019 Apr 13.

Privolzhsky Research Medical University, Minin and Pozharsky square 10/1, Nizhny Novgorod 603950.

The review describes the current understanding of endothelial dysfunction, methods of its evaluation, and highlights the advantages and disadvantages of various techniques. The role of nitric oxide and endothelin as important markers of endothelial dysfunction is shown, and the methods of their determination in clinical practice are described. The authors conclude that in order to improve the life expectancy and quality of life of patients with cardiovascular diseases, reduce the risk and frequency of complications and mortality rates, it is necessary to study the function of endothelium in more detail and to look for ways of drug correction, taking into account the pathogenetic mechanisms of its formation. Read More

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http://dx.doi.org/10.18087/cardio.2524DOI Listing

[The Clinical use of Stress Echocardiography in Ischemic Heart Disease Cardiovascular Ultrasound (2017)15:7. Translation authors: Arystan A.Zh., Fettser D.V.]

Kardiologiia 2019 Apr 13;59(3):78-96. Epub 2019 Apr 13.

City Clinical Hospital №52 Moscow.

Stress echocardiography is an established technique for the assessment of extent and severity of coronary artery disease. The combination of echocardiography with a physical, pharmacological or electrical stress allows detecting myocardial ischemia with an excellent accuracy. A transient worsening of regional function during stress is the hallmark of inducible ischemia. Read More

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https://lib.ossn.ru/jour/article/view/579
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http://dx.doi.org/10.18087/cardio.2019.3.10244DOI Listing
April 2019
2 Reads

[Infective Endocarditis Causing Native and Prosthetic Heart Valve Dysfunction].

Kardiologiia 2019 Apr 13;59(3):68-77. Epub 2019 Apr 13.

Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo.

Infective endocarditis (IE) is the disease that has high inhospital mortality. Heart valves dysfunction - both native and prosthetic - is the primary IE complication requiring a surgical intervention. The IE causes and its course have been discussed in this review. Read More

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http://dx.doi.org/10.18087/cardio.2019.3.10245DOI Listing
April 2019
3 Reads

[Ghrelin Physiology and Pathophysiology: Focus on the Cardiovascular System].

Kardiologiia 2019 Apr 13;59(3):60-67. Epub 2019 Apr 13.

Research Institute for Complex Issues of Cardiovascular Diseases Kemerovo State Medical University.

Ghrelin is a multifunctional peptide hormone, mainly synthesized by P / D1 cells of the stomach fundus mucosa. Its basic effect, which is realized via GHS-R1 α receptor in the arcuate and the ventromedial nucleuses of hypothalamus, is stimulation of the synthesis of pituitary hormones. Ghrelin is involved in control of appetite and energy balance, regulation of carbohydrate and lipid metabolism, cell proliferation and apoptosis, as well as modulation of functioning of gastrointestinal, cardiovascular, pulmonary and immune systems. Read More

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https://lib.ossn.ru/jour/article/view/569
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http://dx.doi.org/10.18087/cardio.2019.3.10220DOI Listing
April 2019
2 Reads

[Progress and Problems of Practical Cardiology in Russia at the Present Stage].

Kardiologiia 2019 Apr 13;59(3):53-59. Epub 2019 Apr 13.

National Medical Research Centre of Cardiology.

Mortality of the population due to diseases of the cardiovascular system is the most acute problem in Russia. According to the World Health Organization, the standardized death rate from cardiovascular diseases in the Russian Federation remains one of the highest in Europe. This review presents statistical data on morbidity and mortality from cardiovascular diseases in the Russian Federation and analyzes the delivery of medical care to patients with these diseases in 2017. Read More

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http://dx.doi.org/10.18087/cardio.2019.3.10242DOI Listing
April 2019
1 Read

[In memory of Mikhail Yakovlevich Ruda].

Kardiologiia 2019 Apr 13;59(3):567. Epub 2019 Apr 13.

. Read More

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[Electrhopysiological Effect of the Polyamine Spermine in Normoxic and Ischemic Ventricular Myocardium].

Kardiologiia 2019 Apr 13;59(3):43-51. Epub 2019 Apr 13.

Institute of Experimental Cardiology of National Medical Research Center for Cardiology.

Cytoplasmic polyamines (PA) are involved in control of many cellular functions and are well known as regulators of so called inward-rectifier potassium ion channels. Nevertheless, functional significance of extracellular PA in the heart is poorly elucidated. Aim of this study was to study effects of endogenous PA spermine in the ventricular myocardium. Read More

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http://dx.doi.org/10.18087/cardio.2019.3.10240DOI Listing

[Post Radiotherapy Lesions of the Heart Valves. Principles of Diagnosis and Results of Treatment].

Kardiologiia 2019 Apr 12;59(3):36-42. Epub 2019 Apr 12.

A. N. Bakoulev Scientific Center for Cardiovascular Surgery.

Background: The use of radiation therapy for the treatment of tumors of the chest сan lead to the development of cardiac pathology, including that of the valves and coronary arteries.

Study Aim: to analyze the specifics of post-radiation lesions of the valvular apparatus and coronary arteries, and to assess the immediate results and risks of surgical correction of detected defects. Materials and  methods. Read More

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http://dx.doi.org/10.18087/cardio.2019.3.10239DOI Listing
April 2019
1 Read

[Lipid Lowering Therapy with Statins in Patients with Heterozygous Familial Hypercholesterolemia].

Kardiologiia 2019 Apr 12;59(3):27-35. Epub 2019 Apr 12.

Petrozavodsk State University.

Aim: to analyze adherence of FH patients with familial hypercholesterolemia (FH) to the statin therapy and reveal factors, which influence it; to assess the degree of target level of low-density lipoprotein cholesterol (LDLCH) achievement by FH patients on statin therapy. Materials and methods. We included in this study 203 FH patients aged >18 years (mean age 50. Read More

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https://lib.ossn.ru/jour/article/view/563
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http://dx.doi.org/10.18087/cardio.2019.3.10238DOI Listing
April 2019
2 Reads

[Single Pill Indapamide and Perindopril Arginine Combination: Optimal Coupling of Vascular Protection and Hemodynamic Risk Factors Reduction in Patients with Essential Arterial Hypertension].

Kardiologiia 2019 Apr 12;59(3):18-26. Epub 2019 Apr 12.

A. I. Yevdokimov Moscow State University of Medicine and Dentistry Sechenov First Moscow State Medical University (Sechenov University).

Objective: to investigate the impact of indapamide / perindopril single-pill combination (I / P SPC) on arterial stiffness parameters, blood pressure (BP) level and BP variability (BPV) in middle-aged patients with stage II grade 1-2 essential arterial hypertension (EAH). Materials and methods. We retrospectively formed a group of patients with stage II grade 1-2 EAH who had not previously received regular antihypertensive therapy (AHT) (n=52, mean age 52. Read More

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http://dx.doi.org/10.18087/cardio.2019.3.10236DOI Listing
April 2019
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[Central Aortic Pressure: Reference and Diagnostic Values].

Kardiologiia 2019 Apr 12;59(3):11-17. Epub 2019 Apr 12.

Research Institute of Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences.

Objective: Practical application of central aortic pressure (CAP) parameters is limited by the absence of generally recognized reference and threshold diagnostic indices. The purpose of this work is to establish their values in the general population of Novosibirsk. Materials and Methods. Read More

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https://lib.ossn.ru/jour/article/view/560
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http://dx.doi.org/10.18087/cardio.2019.3.10235DOI Listing
April 2019
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[Polymorphism A1166C of AGTR1 Gene and the State of Intrarenal Blood Flow in Patients with Essential Arterial Hypertension 1-2 Degrees].

Kardiologiia 2019 Apr 12;59(3):5-10. Epub 2019 Apr 12.

Penza Institute for Further Training of Physicians - Branch Campus of the Russian Medical Academy of Continuous Professional Education.

Aim: to study relationship between genetic disorders and features of intrarenal blood flow in patients with essential arterial hypertension (AH) of 1-2 degree.

Materials And Methods: We examined 100 patients (60 women, 40 men) aged 35 to 58 years with 1-2‑degree essential arterial hypertension (AH) and chronic kidney disease (CKD) stages I-III. Examination included triplex scanning of renal arteries on the ultrasound scanner Vivid-7 Dimension, genotyping of single-nucleotide polymorphism А1166С of the AGTR1 gene by real time polymerase chain reaction (PCR), estimation of glomerular filtration rate (GFR) using CKD-EPI formula. Read More

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http://dx.doi.org/10.18087/cardio.2019.3.10233DOI Listing
April 2019
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Tricuspid valve disease: diagnosis, prognosis and management of a rapidly evolving field.

Nat Rev Cardiol 2019 Apr 15. Epub 2019 Apr 15.

Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada.

Tricuspid valve disease, and particularly tricuspid regurgitation, is a highly prevalent condition with a complex pathophysiology and long-term adverse consequences. Although historically neglected, tricuspid valve disease has gained increasing recognition, with important advances in the assessment and management of this disorder over the past 2 decades. Surgical treatment remains the standard of care, but it continues to have one of the the highest death rates among all cardiac valve-related procedures, and a broad range of patients still do not receive effective therapy for tricuspid valve disease in contemporary clinical practice. Read More

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http://dx.doi.org/10.1038/s41569-019-0186-1DOI Listing
April 2019
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Prognostic Significance of Heart Rate Turbulence Parameters in Patients with Noncompaction Cardiomyopathy.

Cardiology 2019 Apr 12;142(1):56-62. Epub 2019 Apr 12.

University of Kyrenia, Department of Cardiology, Kyrenia, Cyprus,

Background: Noncompaction cardiomyopathy (NC) is a rare congenital heart disease characterized by progressive heart failure and life-threatening arrhythmias. Heart rate turbulence (HRT) has been defined as a noninvasive prognostic method to reveal the cardiac death risk in high-risk patients.

Objectives: We aimed to assess the cardiac autonomic functions and their relations to the mortality in NC patients. Read More

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http://dx.doi.org/10.1159/000499408DOI Listing

Safety of Apixaban Administered via Nasogastric Tube.

Cardiology 2019 Apr 12;142(1):39. Epub 2019 Apr 12.

Bristol-Myers Squibb, Innovative Medicines Development, Princeton, New Jersey, USA,

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http://dx.doi.org/10.1159/000495577DOI Listing

Multiple Autoantibodies against Cardiovascular Receptors as Biomarkers in Hypertensive Heart Disease.

Cardiology 2019 Apr 12;142(1):47-55. Epub 2019 Apr 12.

Heart Center and Beijing Key Laboratory of Hypertension Research, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China,

Objectives: The pathogenesis of hypertensive heart disease (HHD) remains unclear, which might include autoimmunity. The aim of the present study was to determine whether a relationship exists between the presence of autoantibodies against β1, β2, α1 adrenoreceptors, M2-muscarinic receptors, angiotensin II type1 receptors and HHD.

Methods: In the present study, 44 patients diagnosed with HHD, 36 patients with hypertension, and 40 controls were also enrolled. Read More

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http://dx.doi.org/10.1159/000497189DOI Listing
April 2019
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Analyses for Prevalence and Outcome of Tricuspid Regurgitation in China: An Echocardiography Study of 134,874 Patients.

Cardiology 2019 Apr 12;142(1):40-46. Epub 2019 Apr 12.

Department of Cardiology, Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, Shanghai, China.

Background: The aim of this study is to investigate the prevalence and outcome of tricuspid regurgitation (TR) in the Chinese population.

Methods: The echocardiography database, including 134,874 patients at our heart center from 2010 to 2012, was retrospectively analyzed.

Results: The rates of mild, moderate, and severe TR were 2. Read More

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http://dx.doi.org/10.1159/000496601DOI Listing
April 2019
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