17,585 results match your criteria Cardiogenic Shock

Understanding the diagnosis and management of multisystem inflammatory syndrome in adults (MIS-A) in the UK: results of a national Delphi process.

Clin Med (Lond) 2022 May;22(3):266-270

Guy's and St Thomas' NHS Foundation Trust, London, UK.

Infection with SARS-CoV-2 may trigger a delayed hyper-inflammatory illness in children called paediatric multisystem inflammatory syndrome temporally associated with COVID-19 (PIMS-TS). A similar syndrome is increasingly recognised in adults termed multisystem inflammatory syndrome in adults (MIS-A) and may present acutely to medical or surgical specialties with severe symptoms, such as acute abdominal pain or cardiogenic shock. No national guidelines exist in the UK for the management of MIS-A and there is limited evidence to guide treatment plans. Read More

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A Comprehensive Appraisal of Risk Prediction Models for Cardiogenic Shock.

Shock 2022 May;57(5):617-629

Section of Interventional Cardiology, Division of Cardiovascular Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.

Abstract: Despite advances in early revascularization, percutaneous hemodynamic support platforms, and systems of care, cardiogenic shock (CS) remains associated with a mortality rate higher than 50%. Several risk stratification models have been derived since the 1990 s to identify patients at high risk of adverse outcomes. Still, limited information is available on the differences between scoring systems and their relative applicability to both acute myocardial infarction and advanced decompensated heart failure CS. Read More

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Pheochromocytoma-Induced Cardiogenic Shock.

Acta Chir Belg 2022 May 18:1-5. Epub 2022 May 18.

Department of Abdominal Surgery, Grand Hôpital de Charleroi, Gilly, Belgium.

Background: Pheochromocytoma is a rare catecholamine-secreting tumor of neuroendocrine origin. It has a prevalence of <1% in adults with hypertension. In some cases, hypertension is associated with the classical triad of headache, sweating, and tachycardia. Read More

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Nephrology Considerations in the Management of Durable and Temporary Mechanical Circulatory Support.

Kidney360 2022 Mar 14;3(3):569-579. Epub 2022 Jan 14.

Selzman Institute for Kidney Health, Section of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas.

Durable and temporary mechanical circulatory support (MCS) use is growing for a range of cardiovascular indications. Kidney dysfunction is common in people evaluated for or receiving durable or temporary MCS and portends worse outcomes. This kidney dysfunction can be due to preexisting kidney chronic kidney disease (CKD), acute kidney injury (AKI) related to acute cardiovascular disease necessitating MCS, AKI due to cardiac procedures, and acute and chronic MCS effects and complications. Read More

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Acute myocardial infarction and sudden cardiac arrest caused by anomalous left coronary artery arising from the noncoronary cusp.

J Cardiol Cases 2022 May 3;25(5):312-315. Epub 2022 Jan 3.

Department of Cardiology, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.

Anomalous left coronary artery arising from the noncoronary cusp (LCANCC) is a rare congenital disorder. We herein describe a 17-year-old female patient with sudden cardiac arrest followed by refractory cardiogenic shock. LCANCC-induced acute myocardial infarction with left main coronary artery involvement was subsequently diagnosed, and the patient required a durable left ventricular assist device. Read More

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Prognostic Role of Residual Thrombus Burden Following Thrombectomy: Insights From the TOTAL Trial.

Circ Cardiovasc Interv 2022 May 17;15(5):e011336. Epub 2022 May 17.

Division of Cardiology, Peter Munk Cardiac Centre, Toronto General Hospital, University Health Network, Canada (M.A., M.K., C.K., V.D.).

Background: It is unclear whether more effective forms of thrombus removal than current aspiration catheters would lead to improved outcomes. We sought to evaluate the prognostic role of residual thrombus burden (rTB), after manual thrombectomy, in patients undergoing primary percutaneous coronary intervention with routine manual thrombectomy in the TOTAL trial (Thrombectomy Versus PCI Alone).

Methods: This is a single-arm analysis of patients from the TOTAL trial who underwent routine manual aspiration thrombectomy. Read More

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Prophylactic Mechanical Circulatory Support Use in Elective Percutaneous Coronary Intervention for Patients With Stable Coronary Artery Disease.

Circ Cardiovasc Interv 2022 May 17;15(5):e011534. Epub 2022 May 17.

Duke Clinical Research Institute, Duke University Medical Center, Durham, NC (M.Z., G.M.G., P.Z., D.M.W., S.V.R., T.Y.W.).

Background: Mechanical circulatory support (MCS) devices can be used in high-risk percutaneous coronary intervention (PCI). Our objective was to describe trends and outcomes of prophylactic MCS use in elective PCI for patients with stable coronary artery disease in the American College of Cardiology National Cardiovascular Data Registry's CathPCI registry.

Methods: Among 2 108 715 consecutive patients with stable coronary artery disease undergoing elective PCI in the CathPCI registry between 2009 and 2018, we examined patterns of prophylactic use of MCS. Read More

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Association of Congenital and Acquired Cardiovascular Conditions With COVID-19 Severity Among Pediatric Patients in the US.

JAMA Netw Open 2022 May 2;5(5):e2211967. Epub 2022 May 2.

Children's Health of Orange County, Orange, California.

Importance: Identifying the associations between severe COVID-19 and individual cardiovascular conditions in pediatric patients may inform treatment.

Objective: To assess the association between previous or preexisting cardiovascular conditions and severity of COVID-19 in pediatric patients.

Design, Setting, And Participants: This retrospective cohort study used data from a large, multicenter, electronic health records database in the US. Read More

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Moderate Hypothermia vs Normothermia and 30-Day Mortality in Patients With Cardiogenic Shock Receiving Venoarterial ECMO.

Tatsuki Uemura

JAMA 2022 May;327(19):1928

Department of Emergency Medicine and Critical Care, Center Hospital of the National Center for Global Health and Medicine, Tokyo, Japan.

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Moderate Hypothermia vs Normothermia and 30-Day Mortality in Patients With Cardiogenic Shock Receiving Venoarterial ECMO-Reply.

JAMA 2022 May;327(19):1928-1929

Université de Lorraine, Centre d'Investigations Cliniques Plurithématique CHRU de Nancy, Nancy, France.

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30-day In Vivo Study of a Fully Maglev Extracorporeal Ventricular Assist Device.

Artif Organs 2022 May 17. Epub 2022 May 17.

Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.

Objective: Cardiogenic shock (CS) often occurs in patients suffering from rapidly progressing end-stage heart failure or acute myocardial infarction. Mechanical circulatory support may be used for patients who do not respond to medication or revascularization to stabilize hemodynamics. Extracorporeal ventricular assist device (Extra-VAD) has been reported successful for patients with cardiogenic shock. Read More

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Optimal surgical timing after post-infarction ventricular septal rupture.

Cardiol J 2022 May 17. Epub 2022 May 17.

Department of Cardiology, Hospital Universitario Ramón y Cajal, IRYCIS, CIBERCV, Madrid, Spain.

Background: Ventricular septal rupture (VSR) following acute myocardial infarction (AMI) is a dangerous condition. Surgical VSR closure is the definitive therapy, but there is controversy regarding the surgical timing and the bridging therapy between diagnosis and intervention. The objective of this study is to analyze the ideal time of surgical repair and to establish the contribution of mechanical circulatory support (MCS) devices on the prognosis. Read More

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Cardiac power output index to define hemodynamic response to Impella support in cardiogenic shock.

Hoong Sern Lim

Int J Artif Organs 2022 May 16:3913988221100278. Epub 2022 May 16.

Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

Background: Early assessment of response to Impella in cardiogenic shock may guide escalation of mechanical circulatory support. Therapeutic goal and response to Impella have not previously been defined. This study tested the hypothesis that targeting 3-h post- Impella cardiac power output index (CPOi)-"hemodynamic response"-in cardiogenic shock is associated with 12-h lactate clearance. Read More

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Machine learning based model for risk prediction after ST-Elevation myocardial infarction: Insights from the North India ST elevation myocardial infarction (NORIN-STEMI) Registry.

Int J Cardiol 2022 May 13. Epub 2022 May 13.

Department of Cardiology, GB, Pant Institute of Postgraduate Medical Education and Research, New Delhi, India. Electronic address:

Background: Risk prediction following ST-Elevation Myocardial Infarction (STEMI) in resource limited countries is critical to identify patients at an increased risk of mortality who might benefit from intensive management.

Methods: North India ST-Elevation Myocardial Infarction (NORIN-STEMI) is an ongoing registry that has prospectively enrolled 3,635 STEMI patients. Of these, 3191 patients with first STEMI were included. Read More

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Mechanical Circulatory Support Weaning with Angiotensin Receptor/Neprilysin Inhibitor (ARNI) in Cardiogenic Shock.

Can J Cardiol 2022 May 13. Epub 2022 May 13.

Unit of Cardiac Intensive Care Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.

This case highlights the potent afterload-reducing effect of intra-aortic balloon pump (IABP) in acute heart failure with reduced ejection fraction (AHFrEF). The AHFrEF is characterized by prominent afterload sensitivity and IABP removal may precipitate pulmonary edema and cardiogenic shock even after adequate decongestion; angiotensin receptor/neprilysin inhibitor initiation during IABP support may bridge towards IABP weaning in such afterload-sensitive patients. Read More

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Impact of pulmonary hypertension in patients with hypertrophic cardiomyopathy presented with cardiogenic shock/acute decompensated heart failure.

Curr Probl Cardiol 2022 May 13:101251. Epub 2022 May 13.

New York Medical College at Westchester Medical Center, New York, NY, USA. Electronic address:

Introduction: There have been no studies focusing on how pulmonary hypertension (PH) affects inpatient outcomes in patients with hypertrophic cardiomyopathy (HCM) hospitalized for acute decompensated heart failure or cardiogenic shock. This study explores inpatient outcomes of patients with HCM, and concomitant PH compared to patients with HCM.

Methods: Based on the National Inpatient Sample (NIS) 2016-2018, patients admitted with a primary diagnosis of acute decompensated heart failure or cardiogenic shock were selected. Read More

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Increased risk of purge system malfunction after Impella 5.0 replacement: a case series.

J Artif Organs 2022 May 16. Epub 2022 May 16.

Department of Cardiology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

The Impella 5.0 is an axial-flow percutaneous ventricular assist device used in patients with cardiogenic shock. Although the recommended period of use is 10 days or less, weaning can be delayed because of ongoing hemodynamic instability. Read More

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Surgical Reconstruction of a Giant Left Ventricular Aneurysm with Prior Unloading using a Microaxial-Pump.

Interact Cardiovasc Thorac Surg 2022 May 16. Epub 2022 May 16.

Department of Cardiac Surgery, University Hospital Mainz, Mainz, Germany.

A 46-year-old male patient presented with cardiac decompensation due to a giant left ventricular aneurysm combined with a severely reduced left ventricular function after a silent myocardial infarction. Left ventricular unloading was performed with a microaxial pump as a bridge to surgery. Myocardial function in the basal segments was preserved and surgical ventricular reconstruction was performed successfully. Read More

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Multisystem Inflammatory Syndrome in a Young Adult Following COVID-19 Infection: A Case Report.

Cureus 2022 Apr 11;14(4):e24042. Epub 2022 Apr 11.

Critical Care Medicine, Mayo Clinic Health System, Mankato, USA.

Multisystem inflammatory syndrome (MIS) after a primary infection with coronavirus disease 2019 (COVID-19) was first recognized in 2020 and presents with similar symptoms as Kawasaki disease, toxic shock syndrome, and macrophage activation syndrome/secondary hemophagocytic lymphohistiocytosis. In children, it is called multisystem inflammatory syndrome in children (MIS-C); in adults, it is termed multisystem inflammatory syndrome in adults (MIS-A). This case offers a unique presentation of MIS in a 20-year-old young adult, who turned 21 years old one week after his presentation. Read More

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Levosimendan's effect on venoarterial extracorporeal membrane oxygenation weaning.

Int J Artif Organs 2022 May 14:3913988221098773. Epub 2022 May 14.

Intensive Care Unit, Queen Elizabeth Hospital, Hong Kong, China.

Background: Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) provides temporary haemodynamic support in refractory cardiogenic shock. Recent retrospective studies on levosimendan on V-A ECMO weaning had conflicting results. This study aimed to determine the association between levosimendan on V-A ECMO weaning success in a tertiary centre in Hong Kong. Read More

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Clinical management of postcardiotomy shock in adults.

Med Intensiva (Engl Ed) 2022 May 12. Epub 2022 May 12.

Servicio de Medicina Intensiva, Complejo Hospitalario Universitario de Canarias, San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain.

Postcardiotomy cardiogenic shock represents the most serious expression of low cardiac output syndrome after cardiac surgery. Although infrequent, it is a relevant condition due to its specific and complex pathophysiology and important morbidity-mortality. The diagnosis requires a high index of suspicion and multimodal hemodynamic monitoring, where echocardiography and the pulmonary arterial catheter play a main role. Read More

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Efficacy of mechanical circulatory support used before versus after primary percutaneous coronary intervention in patients with cardiogenic shock from ST-elevation myocardial infarction: A systematic review and meta-analysis.

Cardiovasc Revasc Med 2022 May 6. Epub 2022 May 6.

Division of Cardiology, Texas Tech University Health Sciences Center, Lubbock, TX, USA.

Background: Optimal timing to initiate mechanical circulatory support (MCS) in patients with ST-elevation myocardial infarction (STEMI) complicated by cardiogenic shock (CS) remains unclear with studies showing conflicting results on whether to start before or after primary percutaneous coronary intervention (PPCI). This study aims to examine the association between mortality and MCS initiated before vs after PPCI in patients with STEMI complicated by CS.

Methods: We systematically searched PubMed, Embase, and Scopus for abstracts and full-text articles from inception to October 2021. Read More

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The prognostic value of global myocardium strain by CMR-feature tracking in immune checkpoint inhibitor-associated myocarditis.

Eur Radiol 2022 May 14. Epub 2022 May 14.

Department of Radiology, Zhongshan Hospital, Fudan University and Shanghai Institute of Medical Imaging, No. 180 Fenglin Road, Shanghai, 200032, China.

Objectives: Immune checkpoint inhibitor (ICI)-associated myocarditis is a potentially fatal complication. Sparse published researches evaluated the prognostic value of cardiovascular magnetic resonance feature tracking (CMR-FT) for ICI-associated myocarditis.

Methods: In the single-center retrospective study, 52 patients with ICI-associated myocarditis and CMR were included from August 2018 to July 2021. Read More

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Association between the Right Ventricular Longitudinal Shortening Fraction and Mortality in Acute Respiratory Distress Syndrome Related to COVID-19 Infection: A Prospective Study.

J Clin Med 2022 May 6;11(9). Epub 2022 May 6.

Department of Anesthesiology and Critical Care Medicine, Amiens University Hospital, F-80054 Amiens, France.

Introduction: Right ventricular systolic dysfunction (RVsD) increases acute respiratory distress syndrome mortality in COVID-19 infection (CARDS). The RV longitudinal shortening fraction (RV-LSF) is an angle-independent and automatically calculated speckle-tracking parameter. We explored the association between RV-LSF and 30-day mortality in CARDS patients. Read More

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Impella to Treat Acute Myocardial Infarct-Related Cardiogenic Shock.

J Clin Med 2022 Apr 26;11(9). Epub 2022 Apr 26.

Heart Center, Copenhagen University Hospital Rigshospitalet, 2100 Copenhagen, Denmark.

Acute myocardial infarction complicated by cardiogenic shock (AMICS), is characterized by critically low cardiac output and decreased myocardial contractility. In this situation, a treatment that unloads the myocardium and restores CO without increasing the myocardial oxygen demand is theoretically appealing. Axial flow pumps offer hemodynamic support without increasing myocardial oxygen consumption. Read More

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Incidence and Outcome of Patients with Cardiogenic Shock and Detection of Herpes Simplex Virus in the Lower Respiratory Tract.

J Clin Med 2022 Apr 22;11(9). Epub 2022 Apr 22.

Department of Medicine I, University Hospital, LMU Munich, 81377 Munich, Germany.

(1) Herpes simplex virus (HSV) reactivation in critically ill patients can cause infection in the lower respiratory tract, prolonging mechanical ventilation. However, the association of HSV reactivation with cardiogenic shock (CS) is unclear. As CS is often accompanied by pulmonary congestion and reduced immune system activity, the aim of our study was to determine the incidence and outcome of HSV reactivation in these patients. Read More

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Impact of SARS-CoV-2 Outbreak on Emergency Department Presentation and Prognosis of Patients with Acute Myocardial Infarction: A Systematic Review and Updated Meta-Analysis.

J Clin Med 2022 Apr 21;11(9). Epub 2022 Apr 21.

Department of Translational Medicine, Maggiore della Carità Hospital, University of Eastern Piedmont, 28100 Novara, Italy.

We performed an updated meta-analysis to robustly quantify admission trends of patients with ST-segment elevation MI (STEMI) and non-ST-segment elevation MI (NSTEMI) during the first wave of the pandemic and to characterize on a large basis the risk profile and early prognosis. Studies having the same observation period for the comparison between SARS-CoV-2 outbreak in 2020 versus control period in 2019 were included. Primary endpoints were the relative variation of hospital admissions, the difference of in-hospital mortality for STEMI and NSTEMI. Read More

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Impact of the Total Ischemia Time on No-Reflow Phenomenon in Patients with ST Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.

Anatol J Cardiol 2022 May;26(5):382-387

Department of Cardiovascular Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Background: No-reflow phenomenon after primary percutaneous coronary intervention is a common condition affecting the outcomes; therefore, studying its predictive factors is helpful in identifying patients at high risk. Our objective was to investigate the impact of the total ischemia time on no-reflow phenomenon and its correlation to thrombolysis in myocardial infarction flow grade after primary percutaneous coronary intervention.

Methods: This study was conducted on 545 patients with ST-elevation myocardial infarc-tion who underwent PPCI; the patients were divided into two groups according to the incidence of no-reflow, TIMI flow ≤2 was considered no-reflow. Read More

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Prognostic Impact of Plasma Glucose on Patients With Cardiogenic Shock With or Without Diabetes Mellitus from the SMART RESCUE Trial.

Am J Cardiol 2022 May 9. Epub 2022 May 9.

Division of Cardiology, Department of Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Although the presence of hyperglycemia has been shown to affect the clinical outcome of patients with cardiogenic shock, the extent of hyperglycemia and its association with prognosis have not been fully addressed in a large population. A total of 1,177 consecutive patients with cardiogenic shock were enrolled from January 2014 to December 2018 at 12 hospitals in South Korea. The primary outcome was in-hospital mortality. Read More

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