46,833 results match your criteria Cardiac Tumors


Management of fetal tumors.

Best Pract Res Clin Obstet Gynaecol 2019 Jan 14. Epub 2019 Jan 14.

Fetal Medicine Unit, Department of Obstetrics and Gynaecology, Mount Sinai Hospital and University of Toronto, Toronto, Canada. Electronic address:

In this review article, we discuss the most common fetal tumors, their prenatal management, and outcomes. Overall, the most important outcome predictors are tumor histology, size, vascularity, and location. Very large lesions, lesions causing cardiac failure, and hydrops and lesions obstructing the fetal airway have the poorest outcome, as they may cause fetal death or complications at the time of delivery. Read More

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http://dx.doi.org/10.1016/j.bpobgyn.2019.01.006DOI Listing
January 2019

Imaging, Surgical, and Pathology Findings of a Myxoid Aortic Sarcoma: When Distal Embolization Uncovers a Bigger Problem.

Aorta (Stamford) 2018 Apr 15;6(2):65-67. Epub 2019 Feb 15.

Division Cardiac Surgery, Indiana University, Indianapolis, Indiana.

Aortic sarcomas are a very rare condition typically characterized by a deceiving presentation. Making a correct diagnosis is based on the application of an algorithm which allows to identify the primary disease site and to obtain a tissue diagnosis. Surgical aortic resection with adjuvant therapy offers the best palliation, particularly in cases of well-differentiated tumors with no evidence of diffuse metastatic spread. Read More

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http://dx.doi.org/10.1055/s-0039-1678548DOI Listing

Rapidly growing breast desmoid tumor with intra-thoracic involvement after reconstructive surgery for breast cancer.

Breast J 2019 Feb 12. Epub 2019 Feb 12.

Department of Surgical Oncology, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.

Desmoid tumors are very rare soft tissue neoplasia that are slow growing and locally aggressive. They grow anywhere in the body and are rarely develop in the breast . Histopathologic examination confirms diagnosis. Read More

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http://doi.wiley.com/10.1111/tbj.13212
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http://dx.doi.org/10.1111/tbj.13212DOI Listing
February 2019
2 Reads

Intravenous leiomyomatosis with different surgical approaches: Three case reports.

World J Clin Cases 2019 Feb;7(3):347-356

Department of Vascular Surgery, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, Guangdong Province, China.

Background: Intravenous leiomyomatosis (IVL) is a rare and complicated disease, which requires surgery by a multidisciplinary team. However, the optimal surgical approach has not been determined.

Case Summary: Here we report three cases of IVL treated with different surgical approaches. Read More

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http://dx.doi.org/10.12998/wjcc.v7.i3.347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369390PMC
February 2019
1 Read

Symptomatic improvement using everolimus in infants with cardiac rhabdomyoma.

Ann Pediatr Cardiol 2019 Jan-Apr;12(1):45-48

Department of Pediatric Cardiology, Care Hospital, Hyderabad, Telangana, India.

Background: Cardiac rhabdomyoma (CR) often shows spontaneous regression and needs close follow-up. These tumors may be associated with tuberous sclerosis complex (TSC), caused by the disinhibition of m-TOR protein.

Objective: The aim of the study is to observe the efficacy of everolimus in infants with significant CR. Read More

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http://dx.doi.org/10.4103/apc.APC_79_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343372PMC
February 2019
1 Read

Cardiac Metastases of Small-Bowel Carcinoid.

Circ Cardiovasc Imaging 2019 Feb;12(2):e008405

Biophysics and Nuclear Medicine (S.E.G., C.B., A.I.), University Hospitals of Strasbourg, University of Strasbourg, France.

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http://dx.doi.org/10.1161/CIRCIMAGING.118.008405DOI Listing
February 2019

A preliminary study of the local biomechanical environment of liver tumors in vivo.

Med Phys 2019 Feb 7. Epub 2019 Feb 7.

Institute for Medical Imaging Technology, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 20030, China.

Purpose: Biomechanical properties can be used as biomarkers to diagnose tumors, monitor tumor development, and evaluate treatment efficacy. The purpose of this preliminary study is to characterize the biomechanical environment of two typical liver tumors, hemangiomas (HEMs) and hepatocellular carcinomas (HCCs), and to investigate the potential of using strain metrics as biomarkers for tumor diagnosis, based on a limited clinical dataset.

Methods: Magnetic resonance (MR) tagging was used to quantify the motion and deformation of the two types of liver tumors. Read More

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http://doi.wiley.com/10.1002/mp.13434
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http://dx.doi.org/10.1002/mp.13434DOI Listing
February 2019
2 Reads

Mortality due to cardiovascular disease, respiratory disease, and cancer in adults with cerebral palsy.

Dev Med Child Neurol 2019 Feb 6. Epub 2019 Feb 6.

Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.

Aim: To compare mortality rates for cardiovascular disease, cancer, and respiratory disease between adults with cerebral palsy (CP) and the general population.

Method: A cohort study was conducted using data from adults with CP in England, identified through a primary care data set (the Clinical Practice Research Datalink), with linked data on death registrations from the Office for National Statistics. Cause of death was categorized according to International Classification of Diseases codes. Read More

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http://dx.doi.org/10.1111/dmcn.14176DOI Listing
February 2019
1 Read

Solitary fibrous tumor of the pleura with Doege-Potter syndrome: Second recurrence in a 93-year-old female.

SAGE Open Med Case Rep 2019 12;7:2050313X18823468. Epub 2019 Jan 12.

Division of Thoracic Surgery, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

Solitary fibrous tumors are rare mesenchymal tumors most commonly arising from the pleura. When associated with paraneoplastic syndrome of hypoglycemia caused by the secretion of a high-molecular-weight form of insulin-like growth factor II, it is referred to as the Doege-Potter syndrome. Surgery with complete tumor resection is the only curative treatment. Read More

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http://dx.doi.org/10.1177/2050313X18823468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349974PMC
January 2019
2 Reads

Racial/Ethnic Disparities in Mortality: Contributions and Variations by Rurality in the United States, 2012⁻2015.

Int J Environ Res Public Health 2019 Feb 2;16(3). Epub 2019 Feb 2.

Centers for Disease Control and Prevention, Office of Minority Health and Health Equity, 4770 Buford Highway, TW-3, Atlanta, GA 30341, USA.

The value of disaggregating non-metropolitan and metropolitan area deaths in illustrating place-based health effects is evident. However, how place interacts with characteristics such as race/ethnicity has been less firmly established. This study compared socioeconomic characteristics and age-adjusted mortality rates by race/ethnicity in six rurality designations and assessed the contributions of mortality rate disparities between non-Hispanic blacks (NHBs) and non-Hispanic whites (NHWs) in each designation to national disparities. Read More

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http://dx.doi.org/10.3390/ijerph16030436DOI Listing
February 2019

[Clinical study on two reconstruction methods of proximal gastrectomy and piggyback jejunal interposition for Siewert Ⅱ or Ⅲ adenocarcinoma of esophagogastric junction].

Zhonghua Wai Ke Za Zhi 2019 Feb;57(2):114-118

Department of Digestive Minimally Invasive Surgery, Shanxi Provincial Cancer Hospital, Taiyuan 030013, China Zong Liang is working on the Department of Gastrointestinal Surgery, Northern Jiangsu People's Hospital, Yangzhou 225001, China.

To evaluate the clinical efficacy of two different digestive tract reconstruction methods in the Siewert Ⅱ or Ⅲ adenocarcinoma of esophagogastric junction underwent proximal gastrectomy and piggyback jejunal interposition. A total of 84 patients with Siewert Ⅱ or Ⅲ AEG who underwent proximal gastrectomy and interposition jejunal anastomosis were enrolled prospectively according to the exclusion criteria, from October 2015 to August 2017 at Department of Digestive Minimally Invasive Surgery, Shanxi Cancer Hospital. There were 61 male and 23 female patients, aged 48-69 years with an average age of 59. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5815.2019.02.008DOI Listing
February 2019
1 Read

Twenty Years of Clinical Experience with Cardiac Myxomas: Diagnosis, Treatment, and Follow Up.

J Cardiovasc Imaging 2019 Jan;27(1):37-47

Division of Cardiology, Hospital of the Government of the City of Buenos Aires Dr. Cosme Argerich, Buenos Aires, Argentina.

Background: Cardiac myxomas are the most frequent cardiac tumors. Although histologically benign, in some cases myxomas may be lethal, due to impairment of cardiac dynamics and their thromboembolic potential. The study aimed to assess the clinical presentation of cardiac myxomas and their correlation with echocardiographic features and to describe the perioperative results and long-term outcome of surgically treated patients. Read More

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http://dx.doi.org/10.4250/jcvi.2019.27.e7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358422PMC
January 2019
1 Read

Multiple calcified amorphous tumors in a patient with end-stage renal disease.

J Echocardiogr 2019 Jan 30. Epub 2019 Jan 30.

Department of Cardiovascular Medicine, University of Tokyo Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1007/s12574-019-00416-1DOI Listing
January 2019

Heart failure in cancer: role of checkpoint inhibitors.

J Thorac Dis 2018 Dec;10(Suppl 35):S4323-S4334

Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany.

The introduction of immune checkpoint inhibitors have greatly improved clinical outcomes in several cancer types, revolutionizing the management of a wide variety of tumors endowed with poor prognosis. Despite its success, high grade immune related adverse events were observed in patients treated with checkpoint inhibitors. While cardiotoxicity was largely underestimated in initial studies, numerous reports of fulminant myocarditis and fatal heart failure (HF) have been recently described. Read More

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http://jtd.amegroups.com/article/view/24914/19525
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http://dx.doi.org/10.21037/jtd.2018.10.07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328397PMC
December 2018
2 Reads

Surprising Bone and Soft Tissue Lesions of the Chest: Pictorial Review.

Semin Musculoskelet Radiol 2019 Feb 30;23(1):85-96. Epub 2019 Jan 30.

Department of Radiology, Ghent University, UZ-Gent, Gent, Belgium.

Although plain radiographs of the chest are usually requested to evaluate the heart, lung, and mediastinum, many bone and soft tissue, metabolic, and congenital lesions can be visible presenting as surprising lesions. Thorough analysis of the lesion characteristics on the chest radiograph, eventually in conjunction with more advanced imaging techniques and in combination with the clinical findings, will lead to the correct diagnosis. Read More

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http://dx.doi.org/10.1055/s-0038-1675549DOI Listing
February 2019
1 Read

Early Cardiac Mitochondrial Molecular and Functional Responses to Acute Anthracycline Treatment in Wistar Rats.

Toxicol Sci 2019 Jan 24. Epub 2019 Jan 24.

CNC - Center for Neuroscience and Cell Biology, University of Coimbra, UC-Biotech, Biocant Park, Cantanhede, Portugal.

Doxorubicin (DOX) is an anticancer drug widely used to treat human and non-human tumors but the late and persistent cardio-toxicity reduces the therapeutic utility of the drug. The full mechanism(s) of DOX-induced acute, sub-chronic and delayed toxicity, which has a preponderant mitochondrial component, remains unclear; therefore, it is clinically relevant to identify early markers to identify patients who are predisposed to DOX-related cardiovascular toxicity.To address this, Wistar rats (16 weeks old) were treated with a single DOX dose (20 mg/Kg, i. Read More

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http://dx.doi.org/10.1093/toxsci/kfz026DOI Listing
January 2019
1 Read

Burn-induced neuroepithelial changes as a delayed cause of mortality in major burns: a case report and literature review.

Int J Burns Trauma 2018 20;8(6):145-148. Epub 2018 Dec 20.

College of Medicine, King Saud bin Abdulaziz University for Health Sciences Riyadh, Saudi Arabia.

Background: Mortality in major burns is caused mainly by multisystem organ failure. Brain lesions in burn patients are rare and predominantly traumatic in nature. Here, we present an unusual case of burn-induced glioma causing rapid neurological deterioration and death. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334216PMC
December 2018
1 Read

Multicomponent non-pharmacological intervention to prevent delirium for hospitalised people with advanced cancer: study protocol for a phase II cluster randomised controlled trial.

BMJ Open 2019 Jan 28;9(1):e026177. Epub 2019 Jan 28.

IMPACCT - Improving Palliative, Aged and Chronic Care through Clinical Research and Translation, University of Technology Sydney, Sydney, New South Wales, Australia.

Introduction: Delirium is a significant medical complication for hospitalised patients. Up to one-third of delirium episodes are preventable in older inpatients through non-pharmacological strategies that support essential human needs, such as physical and cognitive activity, sleep, hydration, vision and hearing. We hypothesised that a multicomponent intervention similarly may decrease delirium incidence, and/or its duration and severity, in inpatients with advanced cancer. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-026177DOI Listing
January 2019
2 Reads

[Cortical blindness as initial manifestation of nonbacterial thrombotic endocarditis].

Medicina (B Aires) 2019 ;79(1):61-63

Instituto de Cardiología y Cirugía Cardiovascular (ICyCC), Hospital Universitario Fundación Favaloro, Buenos Aires, Argentina.

Nonbacterial thrombotic endocarditis, formerly known as marantic endocarditis, it is an infrequent entity in which sterile, fibrin vegetations develop on heart valve leaflets. It is often diagnosed at the time of autopsy or in latestage malignancies. The most common malignancies associated with nonbacterial thrombotic endocarditis are lung, pancreatic, gastric cancer and adenocarcinomas of an unknown primary site. Read More

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January 2019
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Simultaneous integrated boost with helical arc radiotherapy of total skin (HEARTS) to treat cutaneous manifestations of advanced, therapy-refractory cutaneous lymphoma and leukemia - dosimetry comparison of different regimens and clinical application.

Radiat Oncol 2019 Jan 28;14(1):17. Epub 2019 Jan 28.

School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan.

Background: Helical irradiation of the total skin (HITS) was modified as simultaneous integrated boost (SIB)-helical arc radiotherapy of total skin (HEARTS) technique and applied to an acute myeloid leukemia (AML) patient with disseminated leukemia cutis.

Methods: The original HITS plan was revised for different regimens, i.e. Read More

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https://ro-journal.biomedcentral.com/articles/10.1186/s13014
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http://dx.doi.org/10.1186/s13014-019-1220-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348688PMC
January 2019
4 Reads

Current strategies for the targeted treatment of high-grade serous epithelial ovarian cancer and relevance of BRCA mutational status.

J Ovarian Res 2019 Jan 28;12(1). Epub 2019 Jan 28.

Department of Health of Woman and Child, Gynecologic Oncology Unit, Catholic University of Sacred Heart, Largo Agostino Gemelli 8, 00168, Rome, Italy.

Epithelial ovarian cancer is the most lethal gynecologic malignancy. In most women, it is diagnosed at an advanced stage, which largely explains the poor prognosis of this malignancy. Germline mutations of the genes BRCA1 and BRCA2, which encode proteins essential for the repair of double-strand DNA breaks through homologous recombination, lead to increased cancer predisposition. Read More

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http://dx.doi.org/10.1186/s13048-019-0484-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348631PMC
January 2019

Evolution of radiotherapy techniques in breast conservation treatment.

Gland Surg 2018 Dec;7(6):576-595

Radiation Oncology Associates and Genesis Cancer Care Pty Ltd., Macquarie University Hospital, Sydney, Australia.

Radiation therapy (RT) is an important component of breast cancer treatment that reduces local recurrence and improves survival after breast conservation. Breast conservation rates have increased significantly since the late 1980s and techniques have improved with greater awareness of the impact of radiation on the heart. An overview of randomized controlled trials of breast conservation using standard whole breast irradiation, whole breast hypofractionation, accelerated partial breast irradiation (APBI) and intraoperative radiation are reviewed. Read More

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http://dx.doi.org/10.21037/gs.2018.11.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323255PMC
December 2018

Near Total Occlusion of Right Ventricle by Cardiac Mass.

J Cardiothorac Vasc Anesth 2018 Dec 25. Epub 2018 Dec 25.

Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD.

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http://dx.doi.org/10.1053/j.jvca.2018.12.018DOI Listing
December 2018
2 Reads

[Intravenous leiomyomatosis].

Pathologe 2019 Feb;40(1):80-84

Klinik für Kardiovaskuläre Chirurgie, Universitätsklinikum Düsseldorf, Düsseldorf, Deutschland.

Intravenous leiomyomatosis (IVLM) is an unusual neoplasm derived from uterine smooth muscle cells seen in patients with uterine leiomyomas. The typical histological features of IVLM consist of benign smooth muscle cells present within venous vascular spaces of the uterine wall. Increasing intravascular and intracardial spread of IVLM may lead to life-threatening clinical complications. Read More

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http://dx.doi.org/10.1007/s00292-019-0566-7DOI Listing
February 2019
1 Read

Tissue acidosis does not mediate the hypoxia selectivity of [Cu][Cu(ATSM)] in the isolated perfused rat heart.

Sci Rep 2019 Jan 24;9(1):499. Epub 2019 Jan 24.

School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.

Copper-64-Diacetyl-bis(N-methylthiosemicarbazone) [Cu][Cu(ATSM)] is a hypoxia-targeting PET tracer with applications in oncology and cardiology. Upon entering a hypoxic cell, [Cu][Cu(II)(ATSM)] is reduced to a putative [Cu][Cu(I)(ATSM)] species which dissociates to deposit radiocopper, thereby providing hypoxic contrast. This process may be dependent upon protonation arising from intracellular acidosis. Read More

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http://dx.doi.org/10.1038/s41598-018-36145-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346098PMC
January 2019
1 Read

An atlas for clinical target volume definition, including elective nodal irradiation in definitive radiotherapy of biliary cancer.

Oncol Lett 2019 Feb 28;17(2):1784-1790. Epub 2018 Nov 28.

Radiation Oncology Unit, Department of Experimental, Diagnostic and Specialty Medicine, S. Orsola-Malpighi Hospital, I-40138 Bologna, Italy.

Radiotherapy (RT) is a treatment option for advanced biliary tract cancer (BTC), often combined with sequential and/or concurrent chemotherapy. The use of modern RT techniques requires accurate clinical target volume (CTV) definition and delineation. However, guidelines for CTV delineation in BTC are lacking. Read More

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http://dx.doi.org/10.3892/ol.2018.9774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341831PMC
February 2019
1 Read

Unusual endobronchial prostatic metastatic tumor occluding right main bronchus.

Asian Cardiovasc Thorac Ann 2019 Jan 23:218492319827668. Epub 2019 Jan 23.

2 Department of Thoracic Surgery, Liverpool Heart & Chest Hospital, Liverpool, UK.

Endobronchial metastasis from extrapulmonary solid tumors is rare, and endobronchial metastasis from the prostate is even more unusual. An 80-year-old patient presented with significant dyspnea secondary to metastatic stromal cell sarcoma of the prostate, which occluded the right main bronchus. The tumor, causing complete collapse of the right lung, was found on computed tomography and confirmed by bronchoscopy. Read More

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http://dx.doi.org/10.1177/0218492319827668DOI Listing
January 2019
5 Reads

[Differential Diagnosis of Erythrocytosis - Background and Clinical Relevance].

Dtsch Med Wochenschr 2019 Jan 23;144(2):128-135. Epub 2019 Jan 23.

Due to its rare incidence, erythrocytosis frequently represents a challenge for the treating doctors. The erythropoiesis (= production of erythrocytes) is located in the bone marrow, and the hormone erythropoietin (EPO) takes control in its regulation. Therefore, measurement of EPO in serum is one of the main diagnostic steps. Read More

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http://dx.doi.org/10.1055/a-0739-8340DOI Listing
January 2019
4 Reads

Focusing on the premature death of redeployed miners in China: an analysis of cause-of-death information from non-communicable diseases.

Global Health 2019 01 22;15(1). Epub 2019 Jan 22.

School of Public Health, China Medical University, Shenyang, People's Republic of China.

Background: Reducing premature deaths is an important step towards achieving the World Health Organization's sustainable development goal. Redeployed miners are more prone to disease or premature death due to the special occupational characteristics. Our aims were to describe the deaths of redeployed miners, assess the losses due to premature death and identify their main health problems. Read More

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https://globalizationandhealth.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12992-019-0450-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341550PMC
January 2019
5 Reads
2.250 Impact Factor

Right atrial myxoma detected in a child two months after open-heart surgery.

Asian Cardiovasc Thorac Ann 2019 Jan 22:218492319827658. Epub 2019 Jan 22.

2 Damascus University Cardiac Surgery Hospital, Damascus, Syria.

Primary cardiac tumors are rare, and myxomas represent the most common type. Myxoma in a child is very rare. Herein, we present the case of a 4-year-old boy who was diagnosed with a right atrial mass two months after open-heart surgery for removal of a supra-mitral ring and repair of an interatrial septum aneurysm. Read More

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http://dx.doi.org/10.1177/0218492319827658DOI Listing
January 2019
1 Read

A One-Step Autotransplantation Can Facilitate the Excision of Cardiac Tumors Invading the Lung.

Semin Thorac Cardiovasc Surg 2019 Jan 16. Epub 2019 Jan 16.

Division of Cardiovascular and Thoracic Surgery, Duke University Medical Center, Durham, North Carolina.

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http://dx.doi.org/10.1053/j.semtcvs.2019.01.012DOI Listing
January 2019
2 Reads

Systemic transduction of p16 antitumor peptide inhibits lung metastasis of the MBT-2 bladder tumor cell line in mice.

Oncol Lett 2019 Jan 1;17(1):1203-1210. Epub 2018 Nov 1.

Department of Urology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.

p16 (p16) is a key molecule in bladder tumor (BT) development. We previously reported that a p16 antitumor peptide inhibited the growth of subcutaneous BT grafts in mice through restoration of p16 function using a Wr-T peptide transporter system. In the present study, the efficacy of mouse p16 peptide administration in a mouse lung metastasis model for BT and also the toxicity of peptides by cardiac peptide injection were evaluated. Read More

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http://dx.doi.org/10.3892/ol.2018.9655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312983PMC
January 2019
2 Reads

Nonthrombotic pulmonary embolism caused by intravenous leiomyomatosis: A case report.

Medicine (Baltimore) 2019 Jan;98(3):e14118

Heart Center, Cheng-Hsin General Hospital, Taipei.

Rationale: Pulmonary embolism is a potentially devastating medical condition. Although deep-vein thrombosis is the most common etiology, a nonthrombotic pulmonary embolism is not uncommon.

Patient Concerns: A 45-year-old woman was admitted to our hospital for progressive effort dyspnea for 3 weeks. Read More

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http://dx.doi.org/10.1097/MD.0000000000014118DOI Listing
January 2019
2 Reads

Association between tamoxifen use and acute myocardial infarction in women with breast cancer.

Medicine (Baltimore) 2019 Jan;98(3):e13925

College of Medicine, Tzu Chi University, Hualien.

The relationship between tamoxifen use and acute myocardial infarction in women with breast cancer remains uncertain. The goal of the study was to assess whether tamoxifen use could be associated with acute myocardial infarction in women with breast cancer in Taiwan.A population-based case-control study was conducted to analyze the database of the Taiwan National Health Insurance Program. Read More

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http://Insights.ovid.com/crossref?an=00005792-201901180-0001
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http://dx.doi.org/10.1097/MD.0000000000013925DOI Listing
January 2019
3 Reads

Blastic plasmacytoid dendritic cell neoplasm with response to pralatrexate.

Ann Hematol 2019 Mar 16;98(3):801-803. Epub 2019 Jan 16.

Division of Hematology, Shonan Kamakura General Hospital, 1370-1 Okamoto, Kamakura, Kanagawa, 247-0072, Japan.

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http://dx.doi.org/10.1007/s00277-019-03611-3DOI Listing
March 2019
1 Read

Pitfalls in the Interpretation of Publications about Endoscopic Submucosal Dissection of Early Gastric Cancer with Undifferentiated-Type Histology.

Clin Endosc 2019 Jan 17;52(1):30-35. Epub 2019 Jan 17.

Department of Internal Medicine, Hallym University College of Medicine, Chuncheon Sacred Heart Hospital, Chuncheon, Korea.

Endoscopic submucosal dissection (ESD) is a standard treatment for patients with gastrointestinal neoplasms with a negligible risk of lymph node metastasis. ESD enables en bloc resection of gastrointestinal neoplasms and organ preservation, thereby, avoiding surgical treatment. Although small (<2 cm) intramucosal early gastric cancer with undifferentiated-type histology (EGC-UH) without ulceration is included in the expanded criteria for ESD, controversies remain due to different biology and characteristics compared to EGC with differentiated-type histology. Read More

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http://dx.doi.org/10.5946/ce.2018.158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370935PMC
January 2019

Ascites relative enhancement during hepatobiliary phase after Gd-BOPTA administration: a new promising tool for characterising abdominal free fluid of unknown origin.

Eur Radiol 2019 Jan 14. Epub 2019 Jan 14.

Department of Radiology, Bolzano Central Hospital, via Boehler 5, 39100, Bolzano, Italy.

Objectives: To correlate the degree of ascites enhancement during hepatobiliary phase after gadobenate dimeglumine (Gd-BOPTA) administration with ascites aetiology.

Methods: IRB-approved retrospective study, need for informed consent was waived. We included 74 consecutive ascitic patients who underwent Gd-BOPTA-enhanced liver MRI including hepatobiliary phase (HBP) images between January 2014 and December 2017. Read More

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http://dx.doi.org/10.1007/s00330-018-5932-yDOI Listing
January 2019
2 Reads

Incidence rate and risk factors of early repolarization in patients with growth hormone-secreting pituitary adenoma: a cohort study.

Ther Clin Risk Manag 2019 28;15:65-72. Epub 2018 Dec 28.

Department of Neurosurgery and Pituitary Tumor Center, The First Affiliated Hospital, SunYat-sen University, Guangzhou, People's Republic of China,

Purpose: To investigate the incidence and risk factors for early repolarization (ER) in patients with growth hormone (GH)-secreting pituitary adenomas.

Methods: From August 2014 to August 2016, patients with GH-secreting pituitary adenomas and non-functioning pituitary adenomas admitted to the First Affiliated Hospital, Sun Yat-sen University, were prospectively enrolled. Logistic regression analysis was used to investigate risk factors for ER development. Read More

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http://dx.doi.org/10.2147/TCRM.S185929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314049PMC
December 2018
3 Reads

Co-delivery doxorubicin and silybin for anti-hepatoma via enhanced oral hepatic-targeted efficiency.

Int J Nanomedicine 2019 28;14:301-315. Epub 2018 Dec 28.

Drug Delivery Research Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, People's Republic of China,

Background: To establish the combination of doxorubicin (DOX) and silybin (SLB) in oral hepatic-targeting liposomes with the goal of reducing cardiotoxic side effects and improve oral hepatoma treatment.

Methods: Distearoylphosphatidylethanolamine-polyethylene glycol-cholic acid-modified liposomes (CA-LP) were used to encapsulate DOX and SLB (CA-LP-DOX/SLB), and the hepatic targeting, efficacy against hepatoma and cardioprotective effects were evaluated by cell toxicity, scratch and apoptosis in vitro studies, and pharmacokinetics and pharmacodynamics in vivo studies.

Results: In vitro cell studies showed that CA-LP-DOX/SLB inhibited HepG2 cell proliferation and HCC97H cell migration, and protected H9c2 cells. Read More

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https://www.dovepress.com/co-delivery-doxorubicin-and-silybi
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http://dx.doi.org/10.2147/IJN.S187888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314320PMC
February 2019
7 Reads

[Application of dexmedetomidine in radiofrequency ablation of liver tumor].

Zhonghua Yi Xue Za Zhi 2019 Jan;99(1):25-29

Department of Interventional Therapy, Affiliated Tumor Hospital of Tianjin Medical University, National Clinical Medical Research Center of Cancer, Tianjin Municipal Key Laboratory of Cancer Prevention and Treatment, Tianjin Clinical Medical Research Center of Malignant Tumors, Tianjin 300060, China.

To evaluate the efficacy and safety of dexmedetomidine as a basic analgesic sedative for patients with radiofrequency ablation of liver tumors. A total of 443 liver cancer patients underwent percutaneous radiofrequency ablation in the 302 Hospital of PLA from January 2015 to December 2016 were retrospectively studied. The experimental group was dexmedetomidine group, with a total of 165 cases. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.01.006DOI Listing
January 2019
2 Reads

Pheochromocytoma-related cardiomyopathy presenting as broken heart syndrome: Case report and literature review.

Int J Surg Case Rep 2019 Jan 9;55:7-10. Epub 2019 Jan 9.

Department of Surgery, Kendall Regional Medical Center, Miami, FL, United States.

Introduction: Pheochromocytoma are neuroendocrine tumors that arise from sympathetic chromaffin cells within the adrenal medulla. They principally secrete catecholamines, potentially causing life-threatening cardiovascular complications. A myriad of symptomatology and clinical findings are associated with pheochromocytoma, including a catecholamine-induced dilated cardiomyopathy. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330378PMC
January 2019
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Relaxin gene therapy: A promising new treatment option for various diseases with aberrant fibrosis or irregular angiogenesis.

Mol Cell Endocrinol 2019 Jan 11. Epub 2019 Jan 11.

Department of Bioengineering, College of Engineering, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, 133-791, Seoul, Republic of Korea; Institute of Nano Science and Technology (INST), Hanyang University, Republic of Korea. Electronic address:

Relaxin (RLX) is an insulin-like polypeptide hormone that was initially introduced for its pregnancy-related function. Subsequent studies revealed that RLX possesses anti-fibrotic functions in tumors and nonreproductive tissues, such as skin, lungs, and others. This aspect of the RLX has been explored for the treatment of various illnesses, such as cardiac fibrosis, liver fibrosis, and solid tumors. Read More

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http://dx.doi.org/10.1016/j.mce.2019.01.009DOI Listing
January 2019
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Clinical and Ultrasound Characteristics of the Microcystic Elongated and Fragmented (MELF) Pattern in Endometrial Cancer According to the International Endometrial Tumor Analysis (IETA) criteria.

Int J Gynecol Cancer 2019 Jan;29(1):119-125

Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.

Objectives: To describe sonographic features of the microcystic elongated and fragmented (MELF) pattern of myometrial invasion (MI) using the International Endometrial Tumor Analysis (IETA) criteria; to assess the effect of the MELF pattern on preoperative ultrasound evaluation of MI; and to determine the relationship of the MELF pattern to more advanced stage (≥ IB) and lymph node metastases (LNM) in women with endometrioid endometrial cancer (EEC).

Methods/materials: We included 850 women with EEC from the prospective IETA 4 study. Ultrasound experts performed all ultrasound examinations, accordingto the IETA protocol. Read More

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http://ijgc.bmj.com/lookup/doi/10.1136/ijgc-2018-000045
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http://dx.doi.org/10.1136/ijgc-2018-000045DOI Listing
January 2019
6 Reads

The diagnosis and treatment of cardiac lymphangioma: A case report and literature review.

Medicine (Baltimore) 2019 Jan;98(2):e14000

Department of Cardiac Surgery, The First Affiliated Hospital of Bengbu Medical College, Bengbu, People's Republic of China.

Rationale: Cardiac lymphangioma is a rare disease. Until now, there have been only a few cases of cardiac lymphangioma reported in the literature.

Patient Concerns: We report the case of a 57-year-old female patient with cardiac lymphangioma from atrial septum. Read More

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http://dx.doi.org/10.1097/MD.0000000000014000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336646PMC
January 2019
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Resting-State Functional Connectivity of the Middle Frontal Gyrus Can Predict Language Lateralization in Patients with Brain Tumors.

AJNR Am J Neuroradiol 2019 Feb 10;40(2):319-325. Epub 2019 Jan 10.

Departments of Radiology (M.E.L., M.J., K.P., V.H., A.I.H., B.V.)

Background And Purpose: A recent study using task-based fMRI demonstrated that the middle frontal gyrus is comparable with Broca's area in its ability to determine language laterality using a measure of verbal fluency. This study investigated whether the middle frontal gyrus can be used as an indicator for language-hemispheric dominance in patients with brain tumors using task-free resting-state fMRI. We hypothesized that no significant difference in language lateralization would occur between the middle frontal gyrus and Broca area and that the middle frontal gyrus can serve as a simple and reliable means of measuring language laterality. Read More

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http://www.ajnr.org/lookup/doi/10.3174/ajnr.A5932
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http://dx.doi.org/10.3174/ajnr.A5932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375738PMC
February 2019
6 Reads

Long-term results of a phase II study of hypofractionated proton therapy for prostate cancer: moderate versus extreme hypofractionation.

Radiat Oncol 2019 Jan 10;14(1). Epub 2019 Jan 10.

Center for Prostate Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 10408, Republic of Korea.

Background: We performed a prospective phase II study to compare acute toxicity among five different hypofractionated schedules using proton therapy. This study was an exploratory analysis to investigate the secondary end-point of biochemical failure-free survival (BCFFS) of patients with long-term follow-up.

Methods: Eighty-two patients with T1-3bN0M0 prostate cancer who had not received androgen-deprivation therapy were randomized to one of five arms: Arm 1, 60 cobalt gray equivalent (CGE)/20 fractions/5 weeks; Arm 2, 54 CGE/15 fractions/5 weeks; Arm 3, 47 CGE/10 fractions/5 weeks; Arm 4, 35 CGE/5 fractions/2. Read More

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http://dx.doi.org/10.1186/s13014-019-1210-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327508PMC
January 2019
2 Reads