1,655,891 results match your criteria Cardiac MRI - Technical Aspects Primer
Rev Bras Ginecol Obstet 2018 Dec 14. Epub 2018 Dec 14.
Department of Postgraduate Program and Obstetrics and Gynecology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil.
Objective: To evaluate the accuracy of the diagnosis of fetal heart diseases obtained through ultrasound examinations performed during the prenatal period compared with the postnatal evaluation.
Methods: A retrospective cohort study with 96 pregnant women who were attended at the Echocardiography Service and whose deliveries occurred at the Complexo Hospitalar Santa Casa de Porto Alegre, in the state of Rio Grande do Sul, Brazil. Risk factor assessment plus sensitivity and specificity analysis were used, comparing the accuracy of the screening for congenital heart disease by means of obstetrical ultrasound and morphological evaluation and fetal echocardiography, considering < 0. Read More
Eur Heart J 2018 Dec 13. Epub 2018 Dec 13.
Department of Cardiology, University of Groningen, Hanzeplein 1, Groningen, the Netherlands.
Aims: We sought to determine subtypes of patients with heart failure (HF) with a distinct clinical profile and treatment response, using a wide range of biomarkers from various pathophysiological domains.
Methods And Results: We performed unsupervised cluster analysis using 92 established cardiovascular biomarkers to identify mutually exclusive subgroups (endotypes) of 1802 patients with HF and reduced ejection fraction (HFrEF) from the BIOSTAT-CHF project. We validated our findings in an independent cohort of 813 patients. Read More
Eur J Cardiothorac Surg 2019 Jan;55(1):163-171
Department of Cardiovascular Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Eur Heart J 2018 Dec;39(47):4136-4138
Division of Cardiovascular Medicine, Department of Medicine, Case Western Reserve University School of Medicine, 11100 Euclid Ave, Mailstop LKS 5038, Cleveland, Ohio, Phone: (216) 844-7760, Fax: (216) 844-8954.
Eur Heart J 2018 Dec;39(47):4139-4142
Department of Medicine I, University Hospital Munich, Ludwig Maximilian University, Campus Innenstadt, Ziemssenstrasse 1, Munich, Germany.
Eur Heart J 2018 Dec;39(47):4127-4131
Imperial College and Consultant and Director of Research, Education & Development, Royal Brompton and Harefield Hospital Trust, London, UK.
J Electrocardiol 2018 Dec 6;52:109-111. Epub 2018 Dec 6.
Internal Medicine Department, Hospital Universitario, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
Lyme disease is the most common tick-borne illness in North America. A 23-year-old female presented to our emergency department with a chief complaint of sudden dyspnea and chest pain. An electrocardiogram revealed a third degree heart block. Read More
J Electrocardiol 2018 Dec 4;52:106-108. Epub 2018 Dec 4.
Cardiovascular Division, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Biomed Pharmacother 2018 Dec 11;111:1-5. Epub 2018 Dec 11.
Department of Cardiology, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 20025, PR China. Electronic address:
The interleukin-1 (IL-1) signaling pathway plays a vital role in multiple mechanisms associated with myocardial ischemia-reperfusion (I/R) injury, including inflammation and apoptosis. An IL-1 receptor antagonist (IL-1Ra) can block IL-1 by competitive binding to the IL-1 receptor type I (IL-1RI) and thus may provide a cardioprotective effect. In the present investigation, we determined whether exogenous administration of recombinant human IL-1Ra (rhIL-1Ra) provides a protective role against myocardial I/R injury. Read More
J Control Release 2018 Dec 11. Epub 2018 Dec 11.
Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, 02841, Republic of Korea. Electronic address:
Cancer nanomedicine using nanoparticle-based delivery systems has shown outstanding promise in recent decades for improving anticancer treatment. However, limited targeting efficiency, low drug loading efficiency and innate toxicity of nanoparticles have caused severe problems, leaving only a few available in the clinic. Here, we newly developed carrier-free nanoparticles of cathepsin B-cleavable peptide (Phe-Arg-Arg-Gly; FRRG)-conjugated doxorubicin (DOX) prodrug (FRRG-DOX) that formed a stable nanoparticle structure with an average diameter of 213 nm in aqueous condition. Read More
Neoplasia 2018 Dec 11;21(1):132-145. Epub 2018 Dec 11.
Department of Biomedical Engineering, College of Engineering, The Ohio State University, Columbus, OH 43210; The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210. Electronic address:
The organization of the extracellular matrix has a profound impact on cancer development and progression. The matrix becomes aligned throughout tumor progression, providing "highways" for tumor cell invasion. Aligned matrix is associated with breast density and is a negative prognostic factor in several cancers; however, the underlying mechanisms regulating this reorganization remain poorly understood. Read More
Heart Rhythm 2018 Dec 11. Epub 2018 Dec 11.
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA.
Background: Stroke risk stratification scores (e.g., CHADS-VASc) are used to tailor therapeutic recommendations for patients with atrial fibrillation (AF) in different risk groups. Read More
Heart Rhythm 2018 Dec 11. Epub 2018 Dec 11.
Department of Cardiac Electrophysiology, The Barts Heart Center, St Bartholomew's Hospital, London, UK; Institute of Cardiovascular Science, University College London, London, UK.
Background: The relationship between the surface ECG T-wave to intracardiac repolarization is poorly understood.
Objectives: This study aimed to examine the association between intracardiac ventricular repolarization and the T-wave on the body surface ECG (SECG).
Methods: 10 normal heart patients (age 35 +/- 15yrs, 6Male), were studied. Read More
Heart Rhythm 2018 Dec 11. Epub 2018 Dec 11.
University Hospital Rangueil, Toulouse, France; Unité Inserm U 1048, Toulouse, France. Electronic address:
Background: relationships between hemodynamic consequences of premature ventricular contractions (PVCs) and development of PVC-induced cardiomyopathy (PVC-CM) have not been investigated so far.
Objective: to correlate concealed mechanical bradycardia and/or post-extrasystolic potentiation (PEP) to PVC-CM.
Methods: Invasive arterial pressure from 17 patients with PVC-CM and 16 controls with frequent PVCs were retrospectively analyzed. Read More
Heart Rhythm 2018 Dec 11. Epub 2018 Dec 11.
Cardiology Division, Department of Medicine, Queen Mary Hospital, the University of Hong Kong, Hong Kong SAR, China;; Division of Cardiology, Department of Medicine, the University of Hong Kong Shenzhen Hospital, China;; Shenzhen Institutes of Research and Innovation, University of Hong Kong, China. Electronic address:
Background: The major risk of implanting leadless pacemaker at the right ventricular apex is cardiac perforation.
Objective: We described and prospectively evaluated the safety and feasibility of a technique for mid-septal implantation of the Micra leadless pacemaker.
Methods: We positioning the device at the center of the cardiac silhouette in the right anterior oblique (RAO) view, towards the left in the left anterior oblique (LAO) view and away from the sternum in the left lateral view. Read More
Int J Antimicrob Agents 2018 Dec 11. Epub 2018 Dec 11.
National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS- Via Portuense, 292- 00149 Rome, Italy. Electronic address:
Chronic Hepatitis C (CHC) is a complex disease that can affect different metabolic processes, including glucose and lipids metabolic pathways, with a significant impact on development of heart disease and stroke. The recent therapy with Direct Antiviral Agents (DAAs) beyond the high efficacy on CHC eradication, showed a beneficial impact on glucose and lipid metabolism. This review aims to describe current evidences about the association between HCV infection and impairment of glucose and lipids metabolism and discuss potential public health implications at the light of new DAA therapy and their availability at global level. Read More
J Mol Cell Cardiol 2018 Dec 11. Epub 2018 Dec 11.
Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, United States. Electronic address:
Huntington's disease (HD) is a fatal hereditary neurodegenerative disorder, best known for its clinical triad of progressive motor impairment, cognitive deficits and psychiatric disturbances, is caused by CAG-repeat expansion in exon 1 of Huntingtin (HTT). However, in addition to the neurological disease, mutant HTT (mHTT), which is ubiquitously expressed in all tissues, impairs other organ systems. Not surprisingly, cardiovascular dysautonomia as well as the deterioration of circadian rhythms are among the earliest detectable pathophysiological changes in individuals with HD. Read More
J Mol Cell Cardiol 2018 Dec 11. Epub 2018 Dec 11.
Department of Molecular Physiology and Biophysics, Cardiovascular Research Institute of Vermont, University of Vermont, Burlington, VT, United States. Electronic address:
Rationale: Truncation mutations in the MYBPC3 gene, encoding for cardiac myosin-binding protein C (MyBP-C), are the leading cause of hypertrophic cardiomyopathy (HCM). Whole heart, fiber and molecular studies demonstrate that MyBP-C is a potent modulator of cardiac contractility, but how these mutations contribute to HCM is unresolved.
Objectives: To readdress whether MYBPC3 truncation mutations result in loss of MyBP-C content and/or the expression of truncated MyBP-C from the mutant allele and determine how these mutations effect myofilament sliding in human myocardium. Read More
Arch Biochem Biophys 2018 Dec 11. Epub 2018 Dec 11.
Department of Cardiovascular Disease, Mayo Medical School, Rochester, MN, 55905, USA. Electronic address:
The number of patients with heart failure with reduced ejection fraction (HFrEF) and preserved ejection fraction (HFpEF) is increasing, and for HFpEF, no therapies have clinical benefit. It has been hypothesized that PKG attenuates pathological remodelling, and increasing cGMP would be beneficial for patients with HF. However, neither the RELAX nor NEAT-HFpEF trial showed benefit. Read More
J Appl Clin Med Phys 2018 Dec 14. Epub 2018 Dec 14.
Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Purpose: For prone breast treatment, daily image-guided radiation therapy (IGRT) allows couch shifting to correct breast position relative to the treatment field. This work investigates the dosimetric effect of reducing kV imaging frequencies and the feasibility of optimizing the frequency using patient anatomy or their first 3-day shifts.
Method: Thirty-seven prone breast patients who had been treated with skin marker alignment followed by daily kV were retrospectively analyzed. Read More
PLoS One 2018 14;13(12):e0209088. Epub 2018 Dec 14.
Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Background: We investigated the role of nutritional risk index (NRI) in predicting 1-year mortality in patients with acute decompensated heart failure (ADHF).
Methods: Among 5,625 cohort patients enrolled in Korean Acute Heart Failure (KorAHF) Registry, a total of 5,265 patients who were possible to calculate NRI [NRI = (1.519 x serum albumin [g/dl]) + (41. Read More
PLoS One 2018 14;13(12):e0207980. Epub 2018 Dec 14.
Department of Cardiology, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
Purpose: Quantitative computed tomography (QCT) provides important prognostic information of coronary atherosclerosis. We investigated intraobserver and interobserver QCT reproducibility in asymptomatic individuals, patients with acute chest pain without acute coronary syndrome (ACS), and patients with acute chest pain and ACS.
Methods: Fifty patients from each cohort, scanned between 01/02/2010-14/11/2013 and matched according to age and gender, were retrospectively assessed for inclusion. Read More
J Cardiovasc Med (Hagerstown) 2018 Dec 12. Epub 2018 Dec 12.
Department of Cardiology, 'Sapienza' University of Rome, Rome, Italy.
Dermatol Surg 2018 Dec 13. Epub 2018 Dec 13.
Oaro Dermatology Clinic, Seoul, Republic of Korea.
Background: Thread lifting with absorbable sutures has recently gained prominence for rejuvenating ptotic and sagging soft tissues in aging face. A barbed, delayed absorbable polyglyconate monofilament shows significantly high tensile loads with superior flexibility and elasticity.
Objective: To evaluate the safety and efficacy of novel thread lifting regimen with barbed polyglyconate suture for counteracting the descent and laxity of the aging face. Read More
Med Sci Sports Exerc 2018 Dec 13. Epub 2018 Dec 13.
Department of Sport, Exercise and Health, Faculty of Medicine, University of Basel, Basel, Switzerland.
Purpose: The aim was to determine the minimum secondary exhaustion criteria cut-offs (i.e. max respiratory exchange ratio [RERmax], max heart rate [HRmax], max rating of perceived exertion [RPEmax], and max blood lactate concentration [BLmax]) necessary to determine maximum oxygen uptake (VO2max) during cardiopulmonary exercise tests (CPET), by balancing type I and type II errors. Read More
J Nurs Care Qual 2018 Dec 12. Epub 2018 Dec 12.
Valley Nephrology Associates, Roanoke, Virginia (Drs Saunders and Ahmadzadeh and Ms Wright); Duke University School of Nursing, Durham, North Carolina (Drs Bush and Granger); and Duke Heart Center Nursing Research Program, Durham, North Carolina (Dr Granger).
Background: The commonly employed medication reconciliation process leaves room for mismanagement of medications in the complex end-stage renal disease patient population.
Purpose: The purpose of this quality improvement project was to implement and evaluate a multidisciplinary education and feedback intervention designed to improve self-management for adults with end-stage renal disease.
Methods: A pre-post, same subject repeated measures design was used to evaluate the intervention. Read More
Anesth Analg 2019 Jan;128(1):33-42
Department of Perioperative Medicine, Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.
Postoperative atrial fibrillation (poAF) is the most common adverse event after cardiac surgery and is associated with increased morbidity, mortality, and hospital and intensive care unit length of stay. Despite progressive improvements in overall cardiac surgical operative mortality and postoperative morbidity, the incidence of poAF has remained unchanged at 30%-50%. A number of evidence-based recommendations regarding the perioperative management of atrial fibrillation (AF) have been released from leading cardiovascular societies in recent years; however, it is unknown how closely these guidelines are being followed by medical practitioners. Read More
Anesth Analg 2019 Jan;128(1):19-20
Missoula Anesthesiology and The International Heart Institute of Montana, Missoula, Montana.
A A Pract 2018 Dec 13. Epub 2018 Dec 13.
From the Department of Anesthesia, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, Georgia.
We present a case of a 41-year-old man who suffered cardiac arrest after induction of general anesthesia for an ambulatory ophthalmologic procedure. In this report, we highlight the use of focused transthoracic echocardiography by the anesthesia team to guide a prolonged resuscitation. Emergency room and critical care physicians have described the use of focused echocardiography to aid in diagnosing correctible causes of cardiac arrest, predicting outcomes, and in decision making regarding termination of resuscitation. Read More
A A Pract 2018 Dec 13. Epub 2018 Dec 13.
From the Department of Anesthesiology & Perioperative Care, University of California, Irvine, California.
ε-Aminocaproic acid is routinely used in cardiac surgery to prevent excess bleeding. It is rarely associated with thrombotic events. This case report illustrates the formation of intracardiac thrombi leading to massive pulmonary embolism during a coronary artery bypass graft surgery, secondary to the administration of ε-aminocaproic acid as confirmed by intraoperative transesophageal echocardiogram. Read More
J Strength Cond Res 2018 Dec 13. Epub 2018 Dec 13.
College of Education and Professional Studies, University of Central Oklahoma, Edmond, Oklahoma.
Clark, JC, Baghurst, T, and Redus, BS. Self-selected motivational music on the performance and perceived exertion of runners. J Strength Cond Res XX(X): 000-000, 2018-Music is used by athletes and exercisers to improve performance outcomes, but it is less known whether its properties can enhance performance at maximal intensity. Read More
Am J Physiol Heart Circ Physiol 2018 Dec 14. Epub 2018 Dec 14.
Internal Medicine-Division of Geriatrics, University of Utah, United States.
Blood flow regulation is a critical factor for tissue oxygenation and substrate supply. Increased reactivity of arteries to vasoconstrictors may increase vascular resistance, resulting in reduced blood flow. Here, we aimed to investigate the effect of high fat (HF) diet on stiffness and vasoconstrictor reactivity of white and brown adipose tissue (WAT and BAT) resistance arteries and also investigated the interconversion of both the adipose depots during HF diet condition. Read More
Am J Physiol Heart Circ Physiol 2018 Dec 14. Epub 2018 Dec 14.
Graduate Center for Nutritional Sciences, University of Kentucky, United States.
The deletion of the prorenin receptor (PRR) in adipose tissue elevates systolic blood pressure (SBP) and circulating soluble form of PRR (sPRR) in male mice fed a high-fat diet (HF). However, sex differences in the contribution of adipose-PRR and sPRR to the regulation of the renin-angiotensin system (RAS) in key organs for blood pressure control are undefined. Therefore, we assessed blood pressure and the systemic and intrarenal RAS status in adipose-PRR KO female mice. Read More
Am J Physiol Heart Circ Physiol 2018 Dec 14. Epub 2018 Dec 14.
Institut für Biomedizinische Technik, TU Dresden.
Background-The objective of this study was to quantify repolarization lability and its association with sex, sleep stage and cardiovascular mortality. Methods-We analyzed polysomnographic recordings of 2,263 participants enrolled in the Sleep heart health study (SHHS-2). Beat-to-beat QT interval variability (QTV) was quantified for consecutive epochs of 5 minutes according to the dominant sleep stage (AWAKE, NREM2, NREM3, REM). Read More
Curr Med Res Opin 2018 Dec 14:1-14. Epub 2018 Dec 14.
a Cardiovascular Department , John Hunter Hospital , Newcastle NSW , Australia.
Objective: Pulmonary hypertension may be a consequence of intrinsic elevation in pulmonary vasculature resistance or complicate numerous other conditions affecting the cardiac and respiratory systems. In this review we sought to explore the relationship between pulmonary hypertension and intravenous drug use.
Methods: A narrative review was conducted using PubMed MeSH search with further papers were identified using a standard PubMed search with relevant key terms and various synonyms. Read More
J Exp Psychol Gen 2018 Dec 13. Epub 2018 Dec 13.
UMR CNRS 8240.
Building on the old adage that the deliberate mind corrects the emotional heart, the influential dual process model of moral cognition has posited that utilitarian responding to moral dilemmas (i.e., choosing the greater good) requires deliberate correction of an intuitive deontological response. Read More
Health Psychol 2018 Dec 13. Epub 2018 Dec 13.
Warren Alpert Medical School.
Objective: Self-regulation interventions encouraging daily weighing prevent weight gain in young adults; however, concerns have been raised that such interventions may have undesirable effects on eating pathology, depression, and health-related quality of life (HRQL). The present study examined whether self-regulation interventions and self-weighing frequency were associated with these indices in normal weight individuals and those with overweight or obesity.
Methods: Young adults ( = 599), 18-35 years with a body mass index (BMI) 21. Read More
Psychol Aging 2018 Dec 13. Epub 2018 Dec 13.
Department of Biobehavioral Health and Medicine.
Advancing age is often characterized by preserved or even enhanced emotion regulation, which is thought to manifest in terms of age-related reductions in the within-person association between stressors and negative affect. Existing research from ecological momentary assessment and end-of-day daily diary studies examining such age-related benefits have yielded mixed results, potentially due to differences in samples, design, and measurement of everyday stressors and negative affect. We conducted a coordinated analysis of 5 ecological momentary assessments and 2 end-of-day daily diary studies to examine adult age differences in the within-person association between everyday stressors and negative affect. Read More
Emerg Nurse 2018 Dec 11. Epub 2018 Dec 11.
Jersey General Hospital, St Helier, Jersey.
Atrial fibrillation (AF) is the most common arrhythmia, and there is a one in four lifetime risk of developing the condition for people who are over the age of 40. Vernakalant, a new addition to intravenous antiarrhythmic drugs for cardioversion of AF, is the first atrial-specific antiarrhythmic drug for pharmacological cardioversion of recent onset AF and is more effective than placebo and amiodarone. The drug offers patients an alternative to other pharmacological agents for chemical cardioversion and avoids the risks associated with electrical cardioversion. Read More
J Biomed Opt 2018 Dec;23(12):1-17
Massachusetts General Hospital, Wellman Center for Photomedicine, Boston, Massachusetts, United States.
Photobiomodulation (PBM) therapy, previously known as low-level laser therapy, was discovered more than 50 years ago, yet there is still no agreement on the parameters and protocols for its clinical application. Some groups have recommended the use of a power density less than 100 mW/cm2 and an energy density of 4 to 10 J/cm2 at the level of the target tissue. Others recommend as much as 50 J/cm2 at the tissue surface. Read More
G Ital Nefrol 2018 Dec;35(6)
Unità di Fisiopatologia dell'Insufficienza Renale Acuta e Cronica - Dipartimento di Medicina e Chirurgia, Università degli Studi di Parma.
Acute Kidney Injury (AKI) is an important issue for the healthcare system, as it is associated with high mortality and increased risk of readmission, with consequent elevated healthcare resource utilization. We investigated the incidence of AKI based on the examination of the discharge cards of all patients admitted between January 1 2011 and December 31 2015 at the Parma University Hospital, as well as the frequency and type of 30-day hospital readmission in the patients discharged with a first AKI diagnosis (index admission). The mean pooled 5-year incidence of AKI was 2. Read More
G Ital Nefrol 2018 Dec;35(6)
U.O.C. Nefrologia, Università cattolica del sacro cuore. Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia.
ADH is a hormone secreted by neurohypophysis that plays different roles based on the target organ. At the renal level, this peptide is capable of causing electrolyte-free water absorption, thus playing a key role in the hydro-electrolytic balance. There are pathologies and disorders that jeopardize this balance and, in this field, ADH receptor inhibitors such as Vaptans could play a key role. Read More
Isr Med Assoc J 2018 Dec;20(12):749-753
Heart Institute, Kaplan Medical Center, Rehovot, Israel.
Background: Early identification of patients with a likelihood of cardiac improvement has important implications for management strategies.
Objectives: To evaluate whether tissue Doppler imaging (TDI) and two-dimensional (2D) strain measures may predict left ventricular (LV) improvement in patients with recent onset dilated cardiomyopathy (ROCM).
Methods: Clinical and comprehensive echo were performed at baseline and at 6 months. Read More
Clin Lab 2018 Oct;64(11)
Clin Lab 2018 Oct;64(11)
Background: This study was performed to determine the mRNA expression levels of limb-bud and heart (LBH) in peripheral blood mononuclear cells (PBMCs) from patients with rheumatoid arthritis (RA), and to assess the associations of LBH rs7579944 and rs906868 polymorphisms with RA in a Chinese population. Methods: Real-time transcription-polymerase chain reaction analysis was used to determine the LBH mRNA expression in PBMCs from 53 patients with RA and 58 healthy controls, and LBH rs7579944 and rs906868 polymorphisms were genotyped in 328 RA patients and 449 healthy controls. Results: The LBH mRNA expression levels were significantly decreased in RA patients compared with healthy controls (p = 0. Read More
Multimed Man Cardiothorac Surg 2018 Dec 6;2018. Epub 2018 Dec 6.
Institute of Genetic Medicine, Newcastle University, United Kingdom.
The phenotypic features of the heart with ventricular septal defects will be shown in this video tutorial. There is still no agreement as to whether it's best to categorize lesions on the basis of their geography or their borders. Both geography and borders are features that are of importance. Read More
Multimed Man Cardiothorac Surg 2018 Dec 4;2018. Epub 2018 Dec 4.
Department of Cardiac Surgery and Transplantation, S. Camillo Hospital, Rome, Italy.
Although the benefits of minimally invasive cardiac surgery are well recognized, most surgeons have little experience in the treatment of triple valve disease through a minithoracotomy approach. In this video tutorial, we present a case of concomitant aortic valve replacement with mitral and tricuspid valve repair through a lateral minithoracotomy. Read More
Multimed Man Cardiothorac Surg 2018 Dec 4;2018. Epub 2018 Dec 4.
SS. Antonio e Biagio e Cesare Arrigo Hospital of Alessandria Piedmont Italy.
"One-stage" transmediastinal replacement of the thoracic aorta provides an alternative treatment to single or multiple stage hybrid procedures for patients with ascending, arch, and descending thoracic aorta aneurysm. The patient is placed on bypass and cooled. During circulatory arrest, after surgical treatment of the aortic valve and root where appropriate, the entire ascending aorta is excised and the transverse arch is opened longitudinally. Read More