518 results match your criteria Cardiac Cirrhosis and Congestive Hepatopathy


Differential diagnosis of ascites in internal medicine: clinical case.

Ter Arkh 2018 Aug;90(8):74-80

B.V. Petrovsky Russian Scientific Center of Surgery, Moscow, Russia.

Ascites and hydrothorax may be the symptoms of congestive heart failure and do not always reflects presense of the decompensated liver cirrhosis. Clinical examination of patient with chronic hepatitis C which cyanosis of the lips, cervival veins pulsation, a triple heart rhythm indicated on pathology of the heart (constrictive pericarditis), which was confirmed by instrumental methods. Congestive heart failure has lead to the congestive liver in a young female patient. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.26442/terarkh201890874-80DOI Listing
August 2018
7 Reads

Heart Failure and Liver Disease: Cardiohepatic Interactions.

JACC Heart Fail 2019 Feb 12;7(2):87-97. Epub 2018 Dec 12.

Department of Cardiology, Larissa University General Hospital, Larissa, Greece. Electronic address:

Heart failure (HF) and liver disease often co-exist. This is because systemic disorders and diseases affect both organs (alcohol abuse, drugs, inflammation, autoimmunity, infections) and because of complex cardiohepatic interactions. The latter, which are the focus of this review, include the development of acute cardiogenic liver injury and congestive hepatopathy in HF as well as cardiac dysfunction and failure in the setting of liver cirrhosis, nonalcoholic fatty liver disease, and sequelae following liver transplantation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jchf.2018.10.007DOI Listing
February 2019
10 Reads

Clinical characteristics and thromboembolic risk of atrial fibrillation patients with and without congestive heart failure. Results from the CRATF study.

Medicine (Baltimore) 2018 Nov;97(45):e13074

Cardiology Unit, John Paul II Western Hospital, Grodzisk Mazowiecki.

Congestive heart failure (CHF) and atrial fibrillation (AF) frequently coexist and are associated with increased risk of cardiovascular events.To compare baseline characteristics, comorbidities and pharmacotherapy in AF patients with concomitant CHF to those without CHF.The study included 3506 real-life AF patients with (37. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00005792-201811090-0002
Publisher Site
http://dx.doi.org/10.1097/MD.0000000000013074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250503PMC
November 2018
11 Reads

Significance of congestive heart failure as a cause of pleural effusion: Pilot data from a large multidisciplinary teaching hospital.

Cardiol J 2018 Nov 8. Epub 2018 Nov 8.

Department of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, Poland.

Background: Epidemiological data on the causes of pleural effusion (PE) are scarce. Data on the local prevalence of various causes of PE may play a crucial role in the management strategy of patients with PE. The aim of the study was to investigate the causes of PE and to assess 30-day mortality rate in unselected adult patients treated in a large, multidisciplinary hospital. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5603/CJ.a2018.0137DOI Listing
November 2018
15 Reads

Transcatheter Aortic Valve Replacement to Treat Liver Decompensation.

CASE (Phila) 2018 Oct 9;2(5):186-191. Epub 2018 Aug 9.

Royal Brompton Hospital, London, United Kingdom.

•Critical aortic stenosis can cause severe biventricular disease.•Painless jaundice can present secondary to severe biventricular failure.•TAVR treats high-risk critical aortic stenosis. Read More

View Article

Download full-text PDF

Source
http://www.cvcasejournal.com/article/S2468644118300513/pdf
Web Search
https://www.sciencedirect.com/journal/case
Web Search
https://www.ahajournals.org/doi/abs/10.1161/circintervention
Web Search
https://linkinghub.elsevier.com/retrieve/pii/S24686441183005
Publisher Site
http://dx.doi.org/10.1016/j.case.2018.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200695PMC
October 2018
16 Reads

Heterogeneity of Fibrosis in Liver Biopsies of Patients With Heart Failure Undergoing Heart Transplant Evaluation.

Am J Surg Pathol 2018 Dec;42(12):1617-1624

Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center.

Liver biopsies are commonly performed in heart transplant candidates to confirm congestive hepatopathy (CH) and to assess the degree of fibrosis. Heterogeneity of fibrosis is frequent in CH, making it difficult to stage fibrosis. In this study, we evaluated the prevalence of heterogeneity of fibrosis and nodular regenerative hyperplasia (NRH) in liver biopsies with CH secondary to heart failure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAS.0000000000001163DOI Listing
December 2018
9 Reads

FibroSURE and elastography poorly predict the severity of liver fibrosis in Fontan-associated liver disease.

Congenit Heart Dis 2018 Sep 12;13(5):764-770. Epub 2018 Aug 12.

Department of Gastroenterology, Greenville Memorial Hospital, Greenville, South Carolina.

Objective: As the population of patients with Fontan circulation surviving into adulthood increases, hepatic cirrhosis has grown to be a significant cause of morbidity and mortality. Early detection of advanced hepatic fibrosis is imperative for proper intervention and consideration for heart or combined heart/liver transplantation. Noninvasive biomarkers and elastography have been evaluated for their diagnostic utility with variable results in the Fontan population. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/chd.12650DOI Listing
September 2018
15 Reads
1.202 Impact Factor

Risk factors for recurrent bleeding from acute hemorrhagic rectal ulcer.

Scand J Gastroenterol 2018 Jun - Jul;53(7):831-834. Epub 2018 May 31.

a Department of Gastroenterology and Hepatology , Kurashiki Central Hospital , Kurashiki , Japan.

Objectives: Acute hemorrhagic rectal ulcer (AHRU) occurs suddenly with painless massive bleeding from rectal ulcers, usually in patients who have severe underlying disorders. The rate of recurrent bleeding from AHRU is high, but there have been few studies on the risk factors for recurrent bleeding. The aim of this study was to identify risk factors for recurrent bleeding from AHRU. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/00365521.2018.1476912DOI Listing
November 2018
2 Reads

Isolated hepatic non-obstructive sinusoidal dilatation, 20-year single center experience.

World J Hepatol 2018 May;10(5):417-424

Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, United States.

Aim: To characterize isolated non-obstructive sinusoidal dilatation (SD) by identifying associated conditions, laboratory findings, and histological patterns.

Methods: Retrospectively reviewed 491 patients with SD between 1995 and 2015. Patients with obstruction at the level of the small/large hepatic veins, portal veins, or right-sided heart failure were excluded along with history of cirrhosis, hepatic malignancy, liver transplant, or absence of electrocardiogram/cardiac echocardiogram. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4254/wjh.v10.i5.417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971228PMC
May 2018
3 Reads

Increasing Health Care Burden of Chronic Liver Disease Compared With Other Chronic Diseases, 2004-2013.

Gastroenterology 2018 09 23;155(3):719-729.e4. Epub 2018 May 23.

Baylor College of Medicine, Houston, Texas.

Background & Aims: Chronic liver disease (CLD) is a common and expensive condition, and studies of CLD-related hospitalizations have underestimated the true burden of disease. We analyzed data from a large, diverse health care system to compare time trends in CLD-related hospitalizations with those in congestive heart failure (CHF) or chronic obstructive pulmonary disease (COPD).

Methods: We collected data from a large health care system in Texas on hospitalizations related to CLD (n = 27,783), CHF (n = 60,415), and COPD (n = 34,199) from January 1, 2004 through December 31, 2013. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2018.05.032DOI Listing
September 2018
2 Reads

A subclinical high tricuspid regurgitation pressure gradient independent of the mean pulmonary artery pressure is a risk factor for the survival after living donor liver transplantation.

BMC Gastroenterol 2018 May 15;18(1):62. Epub 2018 May 15.

Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan.

Background: Portopulmonary hypertension (POPH) is characterized by pulmonary vasoconstriction, while hepatopulmonary syndrome (HPS) is characterized by vasodilation. Definite POPH is a risk factor for the survival after orthotopic liver transplantation (OLT), as the congestive pressure affects the grafted liver, while subclinical pulmonary hypertension (PH) has been acknowledged as a non-risk factor for deceased donor OLT. Given that PH measurement requires cardiac catheterization, the tricuspid regurgitation pressure gradient (TRPG) measured by echocardiography is used to screen for PH and congestive pressure to the liver. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-018-0793-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952890PMC
May 2018
8 Reads

Pretransplantation Cystatin C, but not Creatinine, Predicts 30-day Cardiovascular Events and Mortality in Liver Transplant Recipients With Normal Serum Creatinine Levels.

Transplant Proc 2018 May;50(4):1094-1099

Department of Anesthesiology and Pain Medicine, Laboratory for Cardiovascular Dynamics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background: The connection between renal dysfunction and cardiovascular dysfunction has been consistently shown. In patients with liver cirrhosis, renal dysfunction shows a tight correlation with prognosis after liver transplantation (LT); therefore, precise renal assessment is mandatory. Cystatin C, a sensitive biomarker for assessing renal function, has shown superiority in detecting mild renal dysfunction compared to classical biomarker creatinine. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00411345183012
Publisher Site
http://dx.doi.org/10.1016/j.transproceed.2018.01.049DOI Listing
May 2018
3 Reads

Assessment of Advanced Liver Fibrosis and the Risk for Hepatic Decompensation in Patients With Congestive Hepatopathy.

Hepatology 2018 10 22;68(4):1633-1641. Epub 2018 Sep 22.

Division of Gastroenterology & Hepatology, Department of Medicine.

Congestive hepatopathy (CH) arises from chronically elevated right-sided heart pressures transmitted to the liver by passive venous congestion. Over time, CH can lead to hepatic bridging fibrosis, decompensated cirrhosis, and hepatocellular carcinoma. Currently, there are no evidence-based guidelines to direct appropriate screening or management of patients with CH, partly because of the inability of current clinical tools (serum tests, imaging studies, liver stiffness measurements, and liver biopsy) to accurately estimate hepatic fibrosis or the risk for hepatic decompensation. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hep.30048
Publisher Site
http://dx.doi.org/10.1002/hep.30048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173624PMC
October 2018
12 Reads

Using T1 mapping in cardiovascular magnetic resonance to assess congestive hepatopathy.

Abdom Radiol (NY) 2018 Oct;43(10):2679-2685

Department of Radiology, MLC 5031, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.

The goal of this study was to assess the ability of quantitative T1 cardiovascular magnetic resonance (CMR) imaging to calculate liver extracellular volume (ECV) in patients with varying degrees of congestive hepatopathy (CH). T1 measurements and ECV calculations were performed retrospectively in three cohorts of patients: normal cardiac function, tetralogy of fallot (TOF) repair and Fontan palliation. All CMR studies included modified look-locker inversion recovery (MOLLI) T1 mapping scans performed pre- and post-injection of a gadolinium-based contrast agent (GBCA). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00261-018-1528-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120811PMC
October 2018
10 Reads

Liver fibrosis marker, 7S domain of collagen type IV, in patients with pre-capillary pulmonary hypertension.

Int J Cardiol 2018 05 8;258:269-274. Epub 2018 Feb 8.

Department of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.

Background: Pulmonary hypertension (PH) causes right ventricular dysfunction and central venous congestion, and may lead to congestive hepatopathy. The serum 7S domain of collagen type IV (P4NP 7S) is an established marker of liver fibrosis in chronic liver disease. We aimed to determine whether P4NP 7S is related to hemodynamic parameters, and assessed the potential values of P4NP 7S to predict mortality. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2018.01.138DOI Listing
May 2018
4 Reads

Risk and Prognosis of Acute Liver Injury Among Hospitalized Patients with Hemodynamic Instability: A Nationwide Analysis.

Ann Hepatol 2018 January-February;17(1):119-124

Division of Gastroenterology & Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Risk and Prognosis of Acute Liver Injury Among Hospitalized Patients with Hemodynamic Instability: A Nationwide Analysis Introduction and aim. Critically ill patients in states of circulatory failure are at risk of acute liver injury, from mild elevations in aminotransferases to substantial rises consistent with hypoxic hepatitis or "shock liver". The present study aims to quantify the national prevalence of acute liver injury in patients with hemodynamic instability, identify risk factors for its development, and determine predictors of mortality. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5604/01.3001.0010.7543DOI Listing
October 2018
6 Reads

Congestive hepatopathy.

Abdom Radiol (NY) 2018 Aug;43(8):2037-2051

Department of Radiology, Mayo Clinic College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

Passive hepatic congestion may result from a variety of distinct cardiovascular conditions. Injury to the liver caused by congestion is often asymptomatic and may not be recognized clinically. Diagnosis of congestive hepatopathy is important as it has the potential to cause complications including hepatic fibrosis and development of benign and malignant liver masses. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00261-017-1387-xDOI Listing
August 2018
5 Reads

Is Exaggerated Release of Arginine Vasopressin an Endocrine Disorder? Pathophysiology and Treatment.

Authors:
San-E Ishikawa

J Clin Med 2017 Oct 31;6(11). Epub 2017 Oct 31.

Department of Endocrinology and Metabolism, International University of Health and Welfare Hospital, Nasushiobara 329-2763, Tochigi, Japan.

Exaggerated release of arginine vasopressin (AVP) is profoundly involved in impaired water excretion and related hyponatremia. Such disorders underlie syndromes of inappropriate secretion of antidiuretic hormone (SIADH) and edematous diseases, such as congestive heart failure and decompensated liver cirrhosis. All the causes are fundamentally from non-endocrine diseases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jcm6110102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704119PMC
October 2017
1 Read

Severity of coronary artery disease is associated with non-alcoholic fatty liver dis-ease: A single-blinded prospective mono-center study.

PLoS One 2017 26;12(10):e0186720. Epub 2017 Oct 26.

Department of Internal Medicine 1, Hospital of the Goethe University, Frankfurt, Germany.

Background And Aims: Liver steatosis has shown to be associated with coronary artery disease (CAD). The aim of our study was to evaluate the association between the presence and severity of CAD and Non-alcoholic fatty liver disease (NAFLD) assessed by transient elastography (TE) and controlled attenuation parameter (CAP).

Methods: 576 Patients undergoing coronary angiography were enrolled in this prospective study, receiving at least 10 TE and CAP measurements using the FibroScan® M-probe. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186720PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658076PMC
November 2017
18 Reads

Anesthetic management during the first combined heart-liver transplant performed in Korea: a case report.

Korean J Anesthesiol 2017 Oct 14;70(5):571-576. Epub 2017 Jun 14.

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Herein, we describe the anesthetic management during the first combined heart-liver transplant (CHLT) performed in Korea. Though CHLT is a rare procedure, accumulating evidence suggests that it is a feasible option for patients with coexisting heart and liver failure. A 45-year-old female patient presented with severe cardiac dysfunction requiring extracorporeal membrane oxygenation (ECMO) support and secondary congestive hepatopathy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4097/kjae.2017.70.5.571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645592PMC
October 2017
4 Reads

Benign nodules in post-Fontan livers can show imaging features considered diagnostic for hepatocellular carcinoma.

Abdom Radiol (NY) 2017 11;42(11):2623-2631

Department of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.

Purpose: To describe the imaging appearance of hyperenhancing nodules arising in post-Fontan patients and to identify specific features best correlated with malignancy.

Methods: Hyperenhancing hepatic nodules visible on CT and/or MRI in post-Fontan patients were identified retrospectively and reviewed by subspecialty radiologists. Nodules with characteristic imaging findings of focal nodular hyperplasia (FNH) were defined as typical, the remainder were defined as atypical, described in detail according to LIRADS criteria, and length of stability over time was recorded. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00261-017-1181-9DOI Listing
November 2017
30 Reads

Histology and Glutamine Synthetase Immunoreactivity in Liver Biopsies From Patients With Congestive Heart Failure.

Gastroenterology Res 2017 Jun 30;10(3):182-189. Epub 2017 Jun 30.

Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, USA.

Background: Long-standing congestive heart failure can induce a constellation of histopathology changes in the liver that can range from mild sinusoidal dilation to advanced fibrosis and loss of normal perivenular expression of glutamine synthetase (GS). Liver biopsies might be performed to assess the perioperative risk of these patients or to determine the need of synchronous liver transplant. We aimed to assess interobserver agreement in recognizing these liver histologic features in patients undergoing evaluation for heart transplantation and to examine whether immunohistochemistry of GS will aid the diagnosis of cardiac hepatopathy (CH). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14740/gr875eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505284PMC
June 2017
9 Reads

Impact of Cirrhosis in Patients Who Underwent Surgical Aortic Valve Replacement.

Am J Cardiol 2017 Aug 30;120(4):648-654. Epub 2017 May 30.

Department of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address:

Cirrhosis is known to adversely affect cardiac surgery outcomes. Our objective was to quantify the morbidity, mortality, and cost that cirrhosis adds to surgical aortic valve replacement. From 1998 to 2011, 423,789 patients in the Nationwide Inpatient Sample Healthcare Cost Utilization Project underwent isolated aortic valve replacement; 2,769 (0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amjcard.2017.05.034DOI Listing
August 2017
15 Reads

Liver stiffness assessed by Fibrosis-4 index predicts mortality in patients with heart failure.

Open Heart 2017 28;4(1):e000598. Epub 2017 Apr 28.

Department of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.

Objective: Liver dysfunction due to heart failure (HF) is known as congestive hepatopathy. It has recently been reported that liver stiffness assessed by transient elastography reflects increased central venous pressure. The Fibrosis-4 (FIB4) index (age (years) × aspartate aminotransferase (IU/L)/platelet count (10/L) × square root of alanine aminotransferase (IU/L)) is expected to be useful for evaluating liver stiffness in patients with non-alcoholic fatty liver disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/openhrt-2017-000598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471867PMC
April 2017
30 Reads

FIB-4 stage of liver fibrosis predicts incident heart failure among HIV-infected and uninfected patients.

Hepatology 2017 10 30;66(4):1286-1295. Epub 2017 Aug 30.

Vanderbilt University School of Medicine, Nashville, TN.

Liver fibrosis is common, particularly in individuals who are infected with human immunodeficiency virus (HIV). HIV-infected individuals have excess congestive heart failure (CHF) risk compared with uninfected people. It remains unknown whether liver fibrosis stage influences the CHF risk or if HIV or hepatitis C virus (HCV) infection modifies this association. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.29285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609079PMC
October 2017
35 Reads

Heart Disease and the Liver: Pathologic Evaluation.

Gastroenterol Clin North Am 2017 06;46(2):421-435

Department of Pathology and Cell Biology, Columbia University, 630 West 168th Street, PH 15 West, Rm 1574, New York, NY 10032-3725, USA. Electronic address:

Liver injury due to acute and chronic heart failure has long been recognized. This article discusses the concepts of acute cardiogenic liver injury (ACLI) and cardiac or congestive hepatopathy (CH) along with their clinical manifestations and sequelae. Histologically, ACLI manifests as centrilobular hepatocellular necrosis, whereas CH is associated with centrilobular hepatocyte atrophy, dilated sinusoids, and perisinusoidal fibrosis, progressing to bridging fibrosis and ultimately cirrhosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gtc.2017.01.012DOI Listing
June 2017
8 Reads

Hepatic Fibrosis Is Universal Following Fontan Operation, and Severity is Associated With Time From Surgery: A Liver Biopsy and Hemodynamic Study.

J Am Heart Assoc 2017 Apr 26;6(5). Epub 2017 Apr 26.

Division of Cardiology, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

Background: Congestive hepatopathy is a recognized complication of Fontan physiology. Data regarding the incidence of hepatopathy and risk factors are lacking.

Methods And Results: Liver biopsies and cardiac catherizations were performed as part of an evaluation offered to all patients ≥10 years after Fontan. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/JAHA.116.004809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524062PMC
April 2017
15 Reads

Safety Profile of Liver FibroScan in Patients with Cardiac Pacemakers or Implantable Cardioverter-Defibrillators.

Can J Gastroenterol Hepatol 2017 27;2017:7298032. Epub 2017 Feb 27.

Division of Gastroenterology, Department of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.

. Emerging evidence suggests that nonalcoholic fatty liver disease (NAFLD) is associated with coronary artery diseases and arrhythmias. The FibroScan (Echosens, France), a widely available, noninvasive device, is able to detect liver fibrosis and steatosis within this patient population. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2017/7298032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350419PMC
January 2018
4 Reads

Thiazolidinediones and Advanced Liver Fibrosis in Nonalcoholic Steatohepatitis: A Meta-analysis.

JAMA Intern Med 2017 05;177(5):633-640

Department of Medical Sciences, University of Turin, Turin, Italy.

Importance: Nonalcoholic steatohepatitis (NASH) is projected to be the leading cause of liver transplantation by 2020. Advanced fibrosis (stage F3-F4) on liver biopsy independently predicts all-cause and liver-related mortality in NASH. There are no known efficacious treatments for advanced fibrosis related to NASH. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamainternmed.2016.9607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470366PMC
May 2017
4 Reads

Liver health in adults with Fontan circulation: A multicenter cross-sectional study.

J Thorac Cardiovasc Surg 2017 Mar 12;153(3):656-664. Epub 2016 Nov 12.

Department of Cardiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass; Division of Cardiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.

Objectives: Liver disease is an important contributor to morbidity and mortality in patients after Fontan surgery. There has been no large-scale survey of liver health in this population. We sought to explore the prevalence and predictors of liver disease in a multicenter cohort of adults with Fontan physiology. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtcvs.2016.10.060DOI Listing
March 2017
24 Reads

Infective spondylodiscitis in patients on maintenance hemodialysis: a case series.

Ren Fail 2017 Nov 16;39(1):179-186. Epub 2016 Nov 16.

a Department of Nephrology , College of Medicine, Kidney Research Center, Linkou Chang Gung Memorial Hospital, Chang Gung University , Taoyuan , Taiwan.

Infective spondylodiscitis is a rare disease. This case review describes the clinical course, risk factors, and outcomes of adult patients on maintenance hemodialysis who presented with infective spondylodiscitis at a single medical center in Taiwan. There were 18 cases (mean age: 64. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/0886022X.2016.1256313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014531PMC
November 2017
11 Reads

Prevalence and characterization of fibrosis in surveillance liver biopsies of patients with Fontan circulation.

Hum Pathol 2016 11 27;57:106-115. Epub 2016 Jul 27.

Division of Gastroenterology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104.

The Fontan operation is a widely used palliative procedure in patients with single-ventricle anatomy that results in liver injury. As timely identification of liver fibrosis may result in management changes to Fontan patients, the aim of our study was to identify clinically meaningful semi quantitative/quantitative pathologic parameters for biopsy assessment. We performed a retrospective review of 74 liver needle biopsies from Fontan patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.humpath.2016.07.006DOI Listing
November 2016
21 Reads

[Cardiac damage in liver cirrhosis in alcohol abusers].

Ter Arkh 2016;88(8):99-104

Department of Intermediate-Level Therapy, Peoples' Friendship University of Russia, Moscow, Russia, City Clinical Hospital Sixty-Four, Moscow, Russia, Laboratory of Biochemistry, Research Institute of Narcology, Moscow, Russia.

Aim: to estimate the contribution of liver cirrhosis (LC) to the development of heart diseases in alcohol abusers.

Subjects And Methods: The investigation included 80 patients with alcoholic LC without a history of cardiovascular and respiratory diseases and, as a control group, 32 alcohol abusers without a history of chronic diseases of the liver and cardiovascular and respiratory systems; 45 patients with alcoholic cardiomyopathy (ACM) and congestive heart failure without a history of coronary heart disease and valvular diseases, among whom 11 patients were found to have LC. In addition to standard clinical examination, all the patients underwent electrocardiography, by estimating the corrected QT interval (QTc), standard echocardiography; and those without ACM underwent estimation of left ventricular (LV) kinetics using speckle-tracking echocardiography. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17116/terarkh201688899-104DOI Listing
February 2017
4 Reads

A Prediction Rule to Stratify Mortality Risk of Patients with Pulmonary Tuberculosis.

PLoS One 2016 16;11(9):e0162797. Epub 2016 Sep 16.

Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal.

Tuberculosis imposes high human and economic tolls, including in Europe. This study was conducted to develop a severity assessment tool for stratifying mortality risk in pulmonary tuberculosis (PTB) patients. A derivation cohort of 681 PTB cases was retrospectively reviewed to generate a model based on multiple logistic regression analysis of prognostic variables with 6-month mortality as the outcome measure. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0162797PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026366PMC
August 2017
12 Reads

Predictive value of biomarkers of hepatic fibrosis in adult Fontan patients.

J Heart Lung Transplant 2017 Feb 27;36(2):211-219. Epub 2016 Jul 27.

Department of Cardiology, Boston Children's Hospital, Harvard Medical School; Division of Cardiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

Background: Hepatic fibrosis is highly prevalent in individuals with Fontan circulation. FibroSure (LabCorp, Burlington, NC) and hyaluronic acid (HA) have been validated for assessment of hepatic fibrosis in several forms of liver disease. We sought to determine whether these tests could identify Fontan patients with advanced hepatic fibrosis or cirrhosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.healun.2016.07.011DOI Listing
February 2017
28 Reads

Non-alcoholic fatty liver disease-From the cardiologist perspective.

Anatol J Cardiol 2016 07;16(7):534-41

Gr. T. Popa University of Medicine and Pharmacy and Sf. Spiridon Emergency Hospital; Iaşi-România.

Non-alcoholic fatty liver disease (NAFLD) includes a range of disorders characterized by excess accumulation of triglycerides within the liver. While simple steatosis may be clinically stable, non-alcoholic steatohepatitis (NASH) can be progressive. Inflammation is believed to be the driving force behind NASH and the progression to fibrosis and subsequent cirrhosis. Read More

View Article

Download full-text PDF

Source
http://www.journalagent.com/z4/download_fulltext.asp?pdir=an
Publisher Site
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331403PMC
http://dx.doi.org/10.14744/AnatolJCardiol.2016.7049DOI Listing
July 2016
6 Reads

Imaging Findings of Congestive Hepatopathy.

Radiographics 2016 Jul-Aug;36(4):1024-37. Epub 2016 Jun 10.

From the Departments of Radiology (M.L.W., D.M.H., P.M.Y., P.A.A., R.L.E., S.K.V.), Cardiovascular Diseases (E.R.F.), and Pediatric Cardiology (J.T.P.), Mayo Clinic, 200 First St SW, Rochester, MN 55905.

Congestive hepatopathy (CH) refers to hepatic abnormalities that result from passive hepatic venous congestion. Prolonged exposure to elevated hepatic venous pressure may lead to liver fibrosis and cirrhosis. Liver dysfunction and corresponding clinical signs and symptoms typically manifest late in the disease process. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1148/rg.2016150207DOI Listing
March 2017
38 Reads

Right and left ventricular assist devices support and liver dysfunction: prognostic and therapeutic implications.

Curr Opin Cardiol 2016 May;31(3):287-91

aMayo Clinic College of Medicine, Rochester, Minnesota, USA *Dr Simon Maltais and Dr John M. Stulak contributed equally to the writing of this article.

Purpose Of Review: Advanced heart failure is a chronic, systemic disease, which affects other organs in ways that are incompletely understood. Patients with advanced heart failure commonly develop congestive hepatopathy, which may lead to progressive hepatic injury and fibrosis. Because the independent adverse effects of hepatic dysfunction on early and late outcomes after continuous flow left ventricular assist devices have also not been entirely demonstrated, we review its impact on this patient population. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HCO.0000000000000288DOI Listing
May 2016
3 Reads

Hepatocellular carcinoma on cirrhosis complicated with tumoral thrombi extended to the right atrium: results in three cases treated with major hepatectomy and thrombectomy under hypothermic cardiocirculatory arrest and literature review.

World J Surg Oncol 2016 Mar 12;14:83. Epub 2016 Mar 12.

Unit of Surgery, Department of Surgery and Translational Medicine, Careggi University Hospital, Florence, Italy.

Background: Hepatocellular carcinoma (HCC) with the presence of tumor thrombus in hepatic veins and vena cava, until the atrium (RATT), is correlated with poor prognosis and with risk of tricuspid valve occlusion, congestive heart failure, and pulmonary embolism.

Methods: Three patients with HCC on cirrhotic liver with RATT were studied. Operative technique, pre-operative and post-operative liver function tests, blood loss and transfusions, post-operative morbidity and mortality, and the overall survival and the disease free survival were analyzed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12957-016-0831-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789284PMC
March 2016
9 Reads

The story of spironolactones from 1957 to now: from sodium balance to inflammation.

G Ital Nefrol 2016 Feb;33 Suppl 66:33.S66.12

After the discovery of aldosterone (1953), many synthetic steroids were tested for their ability to block the sodium retaining and potassium excreting effect of synthetic mineralocorticoids in adrenalectomized rats. In the same years Kagawa discovered that 17-spirolactone steroids were effective to block mineralocorticoid effects, but when used alone they did not produce any effect in adrenalectomized rats. After the description of the first case of primary aldosteronism (1955), spironolactone (SP) was considered the main treatment before surgery to control blood pressure and kaliemia and for long-term treatment in patients with bilateral adrenal hyperplasia. Read More

View Article

Download full-text PDF

Source
February 2016
3 Reads

[UNMODIFIED DIAMETER V. PORTA. IN 79-YEAR-OLD PATIENT WITH CONGESTIVE HEART FAILURE AND SEVERE PULMONARY HYPERTENSION IN THE SETTING OF COMPLEX CONGENITAL HEART DISEASE--PATENT FORAMEN OVALE AT THE CONFLUENCE OF THE LEFT PULMONARY VEINS INTO THE V. CAVA SUPERIOR AND MIXED (HCV) LIVER CIRRHOSIS].

Eksp Klin Gastroenterol 2015 (6):99-102

The clinical observation and analysis of the reasons for late diagnosis of congenital heart disease is presented. A feature of this observation is diagnosed complex congenital heart defect with shunting of blood in elderly woman with the second disease--chronic viral hepatitis C and cirrhosis of the liver. Long-term compensation circulation and lack of pulmonary fibrosis in our patient with patent foramen ovale was due to the presence of a second malformation--confluence of the left pulmonary veins in vena cava superior that apparently contributed to the constant lung tissue haemooxygenation. Read More

View Article

Download full-text PDF

Source
February 2016
4 Reads

[First Open Study of Syndrome of Acute Decompensation of Heart Failure and Concomitant diseases in Russian Federation: Independent Registry ORAKUL].

Kardiologiia 2015 ;55(5):12-21

Aim of the study was to assess mortality and rate of repetitive hospital admissions on days 30, 90, 180, 360, of observation as well as prevalence of concomitant diseases in patients with congestive heart failure (CHF). The register was formed in 41 centers of 20 cities of Russian Federation. Number of included patients with signs of chronic heart failure (CHF) was 2498. Read More

View Article

Download full-text PDF

Source
January 2016
2 Reads

Frequency of Cardiovascular Events and Effect on Survival in Liver Transplant Recipients for Cirrhosis Due to Alcoholic or Nonalcoholic Steatohepatitis.

Exp Clin Transplant 2016 Feb 17;14(1):79-85. Epub 2015 Nov 17.

From the University of Alabama Medical School, University of Alabama, Birmingham, AL, USA.

Objectives: Frequency of liver transplants because of nonalcoholic steatohepatitis is increasing. Data are conflicting on nonalcoholic steatohepatitis as a risk factor for cardiovascular events after transplant.

Materials And Methods: We reviewed medical records of liver transplant recipients (between years 2005 and 2010) for alcoholic cirrhosis or nonalcoholic steatohepatitis for cardiovascular events (arrhythmia, congestive heart failure, coronary disease, pulmonary hypertension, or stroke) and patient survival within 3 years. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.6002/ect.2015.0089DOI Listing
February 2016
21 Reads

Microfibrillar-Associated Protein 4: A Potential Biomarker for Screening for Liver Fibrosis in a Mixed Patient Cohort.

PLoS One 2015 13;10(10):e0140418. Epub 2015 Oct 13.

Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.

Background And Aims: A method for assessment of liver fibrosis and cirrhosis without the need for a liver biopsy is desirable. Microfibrillar-associated protein 4 (MFAP4) is a suggested biomarker for identification of high-risk patients with severe fibrosis stages. This study aimed to examine associations between plasma MFAP4 (pMFAP4) and transient elastography or chronic hepatitis C virus infection in drug users and in a mixed patient cohort with increased risk of liver disease. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140418PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604125PMC
June 2016
3 Reads

How to interpret liver function tests in heart failure patients?

Turk J Gastroenterol 2015 May;26(3):197-203

Department of Cardiology, Türkiye Yüksek İhtisas Hospital, Ankara, Turkey.

Cardiac hepatopathy has generally been used to describe any liver damage caused by cardiac disorders in the absence of other possible causes of liver damage. Although there is no consensus on the terminology used, cardiac hepatopathy can be examined as congestive hepatopathy (CH) and acute cardiogenic liver injury (ACLI). CH is caused by passive venous congestion of the liver that generally occurs in the setting of chronic cardiac conditions such as chronic HF, constrictive pericarditis, tricuspid regurgitation, or right-sided heart failure (HF) of any cause, and ACLI is most commonly associated with acute cardiocirculatory failure resulting from acute myocardial infarction, acute decompensated HF, or myocarditis. Read More

View Article

Download full-text PDF

Source
http://www.turkjgastroenterol.org/sayilar/285/buyuk/197-203y
Publisher Site
http://dx.doi.org/10.5152/tjg.2015.0086DOI Listing
May 2015
12 Reads

Portal and centrilobular hepatic fibrosis in Fontan circulation and clinical outcomes.

J Heart Lung Transplant 2015 Jul 11;34(7):883-91. Epub 2015 Feb 11.

Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.

Background: The Fontan operation redirects venous blood flow directly to the pulmonary circulation in subjects with single ventricle anatomy. Congestive hepatopathy and cirrhosis have been described in subjects with Fontan circulation, but the prevalence of and predictors for liver disease remain unknown.

Methods: We performed a retrospective study of liver histopathology in Fontan subjects who had liver biopsy or autopsy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.healun.2015.01.993DOI Listing
July 2015
27 Reads

Development of hepatocellular carcinoma in cardiac congestive liver fibrosis: report of a case.

Clin J Gastroenterol 2015 Jun 9;8(3):143-7. Epub 2015 Apr 9.

Department of Surgery, Hyogo College of Medicine, 1-1 Mukogawacho, Nishinomiya, Hyogo, 663-8501, Japan,

We report an extremely rare case of the development of hepatocellular carcinoma (HCC) in cardiac congestive liver fibrosis. A 62-year-old female presented to our hospital with a complaint of right upper quadrant pain. The patient had undergone cardiac surgery for pulmonary valve insufficiency, pulmonary stenosis and atrial septal defect when she was fifteen years of age. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12328-015-0564-0DOI Listing
June 2015
8 Reads

Combination of liver biopsy with MELD-XI scores for post-transplant outcome prediction in patients with advanced heart failure and suspected liver dysfunction.

J Heart Lung Transplant 2015 Jul 23;34(7):873-82. Epub 2014 Dec 23.

Department of Medicine, Division of Cardiology.

Background: Functional and structural liver abnormalities may be found in patients with advanced heart failure (HF). The Model of End-Stage Liver Disease Excluding INR (MELD-XI) score allows functional risk stratification of HF patients on and off anti-coagulation awaiting heart transplantation (HTx), but these scores may improve or worsen depending on bridging therapies and during time on the waiting list. Liver biopsy is sometimes performed to assess for severity of fibrosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.healun.2014.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941637PMC
July 2015
17 Reads

A stepwise approach to the etiologic diagnosis of pleural effusion in respiratory intensive care unit and short-term evaluation of treatment.

Lung India 2015 Mar-Apr;32(2):107-15

Department of Respiratory, Sleep, Allergy and Critical Care Medicine, Metro Centre for Respiratory Diseases, Metro Group of Hospitals, Noida, Uttar Pradesh, India.

Background: Pleural effusions in respiratory intensive care unit (RICU) are associated with diseases of varied etiologies and often carry a grave prognosis. This prospective study was conducted to establish an etiologic diagnosis in a series of such patients before starting treatment.

Materials And Methods: Fifty consecutive patients, diagnosed with pleural effusion on admission or during their stay in RICU, were further investigated by a two-step approach. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/0970-2113.152615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372862PMC
March 2015
3 Reads