Obstet Gynecol 2021 06;137(6):979-987
Mercer University Physician Assistant Program, Atlanta, Georgia; the Centers for Vulvovaginal Disorders the Department of Obstetrics and Gynecology, George Washington University School of Medicine and Health Sciences, Washington, DC; the Department of Pathology and Laboratory Medicine and the Department Obstetrics, Gynecology, and Women's Health, Rutgers New Jersey Medical School, Newark, and Women's Healthcare of Princeton, Princeton, New Jersey; and Strategic Research, Laerdal Medical, Stavanger, Norway.
Objective: To estimate the efficacy of fractionated carbon dioxide (CO2) laser therapy for vulvar lichen sclerosus.
Methods: We conducted a prospective, double-blind, randomized, sham-controlled, trial conducted in a clinic specializing in vulvar disorders. The study participants were 40 women with active vulvar lichen sclerosus confirmed with biopsy who were abstaining from topical and systemic treatments for at least 4 weeks before enrollment. Read More