122 results match your criteria Carbon Dioxide Laser Surgery for Cervical Dysplasia


Effect of age and cone dimensions on cervical regeneration: an Italian multicentric prospective observational study.

BMJ Open 2018 03 19;8(3):e020675. Epub 2018 Mar 19.

Gynecological Oncology Unit, Centro di Riferimento Oncologico - National Cancer Institute, Aviano, Italy.

Objectives: To evaluate cervical regeneration at 6 months following excisional treatment for high-grade cervical intraepithelial neoplasia (CIN), and to investigate the effect of cone dimensions, age of patients and technique of excision on the efficacy of the regeneration process.

Design: Prospective observational multicentric study.

Setting: Three tertiary care and research centres. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2017-02067
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http://dx.doi.org/10.1136/bmjopen-2017-020675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875629PMC
March 2018
12 Reads

Therapeutic Assessment of Vulvar Squamous Intraepithelial Lesions with CO2 Laser Vaporization in Immunosuppressed Patients.

Rev Bras Ginecol Obstet 2018 Jan 16;40(1):26-31. Epub 2018 Jan 16.

Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, São Paulo, Brazil.

Objective:  A vulvar squamous intraepithelial lesion is deemed to be a preceding lesion to vulvar cancer, especially in women aged under 40 years, holders of an acquired or idiopathic immunosuppression. Several treatments have been used to treat these lesions. One of the aesthetically acceptable therapeutic methods is the CO laser vaporization. Read More

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http://dx.doi.org/10.1055/s-0037-1618573DOI Listing
January 2018
1 Read

Obstetrical prognosis of patients with cervical intraepithelial neoplasia (CIN) after "coin-shaped" conization.

Arch Gynecol Obstet 2016 Mar 25;293(3):651-7. Epub 2015 Aug 25.

Department of Obstetrics and Gynecology, Sapporo Medical University, Minami 1 jo, Nishi 16 chome, Chuo-ku, Sapporo, Hokkaido, 060-8543, Japan.

Purpose: Uterine cervical conization is related to adverse pregnancy outcomes in subsequent pregnancies. To deal with this problem, we started conservative coin-shaped conization for reproductive-aged patients with cervical intraepithelial neoplasia (CIN). Here we report both the obstetrical and oncological impacts of this operation in comparison with the standard cone-shaped resection. Read More

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http://dx.doi.org/10.1007/s00404-015-3860-5DOI Listing
March 2016
10 Reads

Clinical presentation, treatment and outcome of vaginal intraepithelial neoplasia.

Arch Gynecol Obstet 2016 Feb 2;293(2):415-9. Epub 2015 Aug 2.

Department of Gynaecology and Obstetrics, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.

Purpose: To characterize the clinical presentation and outcome of patients with vaginal intraepithelial neoplasia (VAIN).

Methods: Medical records of 65 women with VAIN treated between 2005 and 2012 at the colposcopy clinic of a German university hospital were retrospectively evaluated for VAIN grade, HPV status, VAIN localization, treatment method and relapse rate. Follow-up data were available for 53 patients (82 %). Read More

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http://dx.doi.org/10.1007/s00404-015-3835-6DOI Listing
February 2016
7 Reads

Low prevalence of oral and nasal human papillomavirus in employees performing CO2-laser evaporation of genital warts or loop electrode excision procedure of cervical dysplasia.

Acta Derm Venereol 2015 Feb;95(2):173-6

Department of Dermatovenereology, Copenhagen University Hospital, Bispebjerg, DK-2400 Copenhagen, Denmark.

Risk of human papillomavirus (HPV) transmission during laser vaporisation of genital warts or loop electrode excision procedure is controversial. An oral rinse, a nasal swabs, history of HPV related diseases and data on HPV exposure were collected from 287 employees at departments of dermato-venerology and gynaecology in Denmark. A mucosal HPV type was found among 5. Read More

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http://dx.doi.org/10.2340/00015555-1912DOI Listing
February 2015
33 Reads

Therapeutic effect of laser vaporization for vaginal intraepithelial neoplasia following hysterectomy due to premalignant and malignant lesions.

J Obstet Gynaecol Res 2014 Jun;40(6):1740-7

Department of Gynecological Oncology, Beijing Obstetrics and Gynecology Hospital of Capital Medical University, Beijing, China.

Aim: The aim of this study was to evaluate the therapeutic effect of laser vaporization for vaginal intraepithelial neoplasia (VAIN) after hysterectomy in Chinese women and to identify factors affecting persistence/recurrence.

Material And Methods: Twenty-eight VAIN patients after hysterectomy due to cervical intraepithelial neoplasia (group 1) and 11 VAIN patients due to cervical cancer (group 2) were reviewed retrospectively. All patients were treated with at least one episode of laser vaporization between 2010 and 2011, and then followed up every 3 months for at least 1 year. Read More

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http://dx.doi.org/10.1111/jog.12383DOI Listing
June 2014
11 Reads

Risk factors for treatment failure of CO2 laser vaporization in cervical intraepithelial neoplasia 2.

Arch Gynecol Obstet 2014 Jul 24;290(1):115-9. Epub 2014 Jan 24.

Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, 650-9, Yoksam-dong, Gangnam-gu, Seoul, 135-913, Korea.

Purpose: The aim of our study was to evaluate the risk factors for treatment failure of CO2 laser vaporization in patients with cervical intraepithelial neoplasia 2 (CIN2).

Methods: Medical records of patients who received either shallow or deep CO2 laser vaporization with biopsy-proven CIN2 during March 2007 to April 2011 were reviewed retrospectively. After laser vaporization, liquid-based cytology and human papilloma virus (HPV) DNA testing were checked in every follow-up visit. Read More

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http://dx.doi.org/10.1007/s00404-014-3148-1DOI Listing
July 2014
5 Reads

Antisepsis regimen in the surgical treatment of HPV generated cervical lesions: polyhexamethylene biguanide vs chlorhexidine. A randomized, double blind study.

Eur Rev Med Pharmacol Sci 2012 Dec;16(14):1994-8

Department of Obstetrics and Gynecology, University of Perugia, Perugia, Italy.

Introduction: To reduce the risk of local infections after surgical treatments for HPV infected cervical lesions, the post-operative regimen is generally based on the use of vaginal antimicrobial agents.

Aim: The efficacy and safety of polyhexamethylene biguanide-based vaginal suppositories was compared to a similar chlorhexidine-based treatment, in the post recovery regimen after surgical treatment of cervical lesions.

Materials And Methods: 50 women who underwent to CO2 laser therapy for cervical lesions were randomly assigned to receive 10 days of antiseptic treatment with chlorhexidine digluconate vaginal suppositories, or polyhexamethylene biguanide vaginal suppositories (Monogin®/Biguanelle® ovuli, Lo. Read More

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http://www.europeanreview.org/wp/wp-content/uploads/1994-199
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December 2012
10 Reads

[Item 149--Epithelial and melanotic skin tumors: human papillomavirus (HPV) tumors].

Authors:

Ann Dermatol Venereol 2012 Oct 31;139(11 Suppl):A144-9. Epub 2012 Jul 31.

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http://dx.doi.org/10.1016/j.annder.2012.06.012DOI Listing
October 2012
2 Reads

Value-based medicine analysis on loop electrosurgical excision procedure and CO2 laser vaporization for the treatment of cervical intraepithelial neoplasia 2.

J Obstet Gynaecol Res 2012 Aug 8;38(8):1064-70. Epub 2012 May 8.

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College/Chinese Academy of Medical Sciences, Beijing, China.

Aim: The best treatment option for cervical intraepithelial neoplasia 2 (CIN2) is controversial and there is a lack of studies in value-based medicine. This multicenter comparative study was undertaken to evaluate the effectiveness, cost-effectives and quality of life (QOL) of loop electrosurgical excision procedure (LEEP) and CO(2) laser vaporization for the treatment of CIN2.

Material And Methods: A database of LEEP and laser vaporizations performed at three research centers was created. Read More

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http://dx.doi.org/10.1111/j.1447-0756.2011.01832.xDOI Listing
August 2012
6 Reads

Laser vaporization in the management of CIN.

Eur J Gynaecol Oncol 2010 ;31(1):83-6

Department of Gynaecology, Perinatology and Childhealth, University Sapienza, Rome, Italy.

Aims: To evaluate the effectiveness of laser CO2 vaporization in high-grade cervical intraepithelial neoplasias and to assess the diagnostic reliability of cytology, colposcopy, microbiology and HPV tests in predicting recurrence in a long-term outcome.

Methods: Forty-four patients affectd by high-grade cervical intraepithelial neoplasia (HG-CIN) were submitted to laser CO2 vaporization and followed-up a minimum of five years. Vaginal smears for microbiological examination were detected. Read More

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http://jpubhealth.oxfordjournals.org/content/15/4/327.full.p
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April 2010
10 Reads

Management of relapsing cervical intraepithelial neoplasia.

J Reprod Med 2009 Aug;54(8):499-505

First Department of Obstetrics and Gynecology, University of Athens, Athens, Greece.

Objective: To evaluate relapsing cervical intraepithelial neoplasia (CIN) and establish the criteria of recurrence to assess management by laser CO2.

Study Design: Patients with histologically proved CIN after a primary conservative approach were the study population. Disease relapse was considered as residual or recurrent if diagnosed within or after the first year of follow-up. Read More

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August 2009
5 Reads

Retrospective evaluation of CO(2) laser conization in pregnant women with carcinoma in situ or microinvasive carcinoma.

Gynecol Obstet Invest 2009 10;68(4):230-3. Epub 2009 Sep 10.

Department of Obstetrics and Gynecology, Kinki University School of Medicine, Osaka, Japan.

Background: We evaluated the safety and efficacy of CO(2) laser conization in pregnant women with cervical intraepithelial neoplasia 3/carcinoma in situ (CIN3/CIS) or microinvasive carcinoma (MIC).

Objectives: A total of 49 pregnant women with biopsy-proven CIN3/CIS (30 patients) or MIC (19 patients) were studied.

Methods: Retrospective analysis based on clinical records. Read More

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http://dx.doi.org/10.1159/000236366DOI Listing
February 2010
4 Reads

Conservative approach to preneoplastic cervical lesions in postmenopause.

Anticancer Res 2008 Nov-Dec;28(6B):3941-4

Department of Gynaecology, Perinatology and Child Health, University "Sapienza", 00161 Rome, Italy.

Aim: To evaluate the recurrence rate of high-grade squamous intraepithelial lesions in postmenopausal women previously submitted to laser CO2 conization and the role of persistent oncogenic HPV types.

Patients And Methods: Fifty-five patients with a cytological diagnosis of high-grade squamous intraepithelial lesions were triaged with a standard colposcopy. Hormonal replacement therapy was considered as significative in influencing cervical trophism. Read More

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http://ar.iiarjournals.org/content/28/6B/3941.full.pdf
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February 2009
13 Reads

CO2 laser cylindrical excision or standard re-conization for persistent-recurrent high-grade cervical intraepithelial neoplasia (HG-CIN) in women of fertile age.

Anticancer Res 2008 Nov-Dec;28(6B):3871-5

Department of Gynecology, Perinatology and Human Reproduction, University of Florence, Florence, Italy.

Aim: To investigate the therapeutic efficacy of cylindrical or cone-shaped excision performed by laser CO2 in the conservative management of persistent-recurrent high-grade cervical intraepithelial neoplasia (HG-CIN) in women of fertile age.

Patients And Methods: Ninety-four premenopausal patients with persistent-recurrent HG-CIN had undergone re-conization or cylindrical excision according to the time of reappearance of the disease. The length of the procedures, intra- and postoperative complications, height of the excised specimens, final histological findings and follow-up data were retrospectively evaluated. Read More

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February 2009
8 Reads

Oral contraceptives and clinical recurrence of human papillomavirus lesions and cervical intraepithelial neoplasia following treatment.

Int J Gynaecol Obstet 2008 Feb 19;100(2):175-8. Epub 2007 Nov 19.

Department of Gynecology, Perinatology and Child Health, University La Sapienza, Rome, Italy.

Objective: To evaluate the effect of oral contraceptive use on the recurrence rate of human papillomavirus (HPV) lesions and cervical intraepithelial neoplasia (CIN) following ablative or excisional procedures in a long-term follow-up.

Method: The study was conducted with 650 oral contraceptive users presenting with HPV lesions and/or CIN, and 670 women who had these lesions but did not use oral contraceptives acted as controls. The participants underwent cytologic evaluations, colposcopy, and direct biopsy, followed by either ablative treatment by laser carbon dioxide vaporization or excision by a loop electrosurgical excision procedure or cold knife conization. Read More

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http://dx.doi.org/10.1016/j.ijgo.2007.08.023DOI Listing
February 2008
7 Reads

Feasibility and outcome of laser CO2 conization performed within the 18th week of gestation.

Int J Gynecol Cancer 2007 Jan-Feb;17(1):127-31

Department of Gynecology, Perinatology and Human Reproduction, School of Medicine, University of Florence, Via Morgagni 85, 50134 Florence, Italy.

The purpose of this study is to evaluate the feasibility, safety, and potential therapeutic benefit of laser CO(2) conization of the cervix for in situ and minimally invasive carcinoma diagnosed during pregnancy. Twenty-six pregnant patients with biopsy-proven carcinoma in situ/cervical intraepithelial neoplasia III but colposcopically suspicious for invasion underwent laser CO(2) conization during the 18th week of gestation in an outpatient setting under local anesthesia. No major intraoperative or postoperative complications occurred, and cervical cerclage was not required in any case. Read More

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http://doi.wiley.com/10.1111/j.1525-1438.2007.00802.x
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http://dx.doi.org/10.1111/j.1525-1438.2007.00802.xDOI Listing
March 2007
3 Reads

Clinicopathologic outcomes of laser conization for high-grade cervical dysplasia.

Eur J Gynaecol Oncol 2004 ;25(3):305-7

Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.

Purpose Of Investigation: To evaluate the incidence of thermal artifact and rates of persistent disease and recurrence in laser conization for cervical dysplasia.

Methods: A retrospective study examined the cases of 110 patients who underwent carbon dioxide laser conization for high-grade cervical dysplasia at our institution between January 1999 and March 2002. Rates of thermal artifact, persistent disease, recurrence, hemorrhage and cervical stenosis were investigated. Read More

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August 2004
3 Reads

CO2 laser surgery for vulvar intraepithelial neoplasia. Excisional, destructive and combined techniques.

J Reprod Med 2002 Nov;47(11):913-8

Department of Gynecology, Perinatology and Human Reproduction, University of Florence, Florence, Italy.

Objective: To evaluate CO2 laser excision, vaporization and combined techniques for treatment of vulvar intraepithelial neoplasia (VIN).

Study Design: Thirty-nine cases of VIN 3, 15 cases of VIN 2 and 9 of VIN 1, for a total of 63 patients with histologically proven VIN, underwent laser excision or vaporization under colposcopic guidance, using local anesthesia, in an outpatient setting or after day-surgery admission. Clinical aspects, cervical intraepithelial neoplasia (CIN) and vaginal intraepithelial neoplasia (VaIN) association, types of CO2 laser treatment, follow-up, recurrences and second treatments were evaluated. Read More

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November 2002
12 Reads

Vaginal intraepithelial neoplasia: treatment by carbon dioxide laser and risk factors for failure.

Eur J Obstet Gynecol Reprod Biol 2003 Jan;106(1):64-8

Department of Obstetrics and Gynecology, Yale University School of Medicine, Section of Gynecologic Oncology, New Haven, CT, USA.

Objective: To evaluate the effectiveness of CO(2) laser ablation of vaginal intraepithelial neoplasia (VAIN) and to define prognostic factors.

Study Design: Medical records of 24 patients with VAIN II or III, treated by CO(2) laser ablation from 1990 to 1998 were reviewed. The grade, location, and focality of the lesions, the age, follow-up period and menopausal status of the patients, the power and duration of laser ablation, the presence of concurrent cervical or vulvar neoplasia or previous hysterectomy were evaluated as possible prognostic factors. Read More

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January 2003
10 Reads

[Laser conization for cervical intraepithelial neoplasias, grade III. Personal experience of 77 cases].

Minerva Ginecol 2002 Dec;54(6):467-70

Divisione di Ginecologia Oncologica, IFO Polo Oncologico, Rome, Italy.

Background: Evalutation of the efficacy of laser conization for cervical high-grade squamous intraepithelial lesions (Hg-SIL).

Methods: A retrospective evaluation. Case collection: A total of 77 women, 47 outpatients and 30 inpatients with endocervical CIN3 or CIN2, were treated by carbon dioxide (CO2) laser between 1993 and 1995. Read More

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December 2002
2 Reads

Outcomes of carbon dioxide laser conization for the treatment of cervical intraepithelial neoplasia grade III.

Clin Exp Obstet Gynecol 2001 ;28(4):243-5

Department of Obstetrics and Gynecology, Aristoteleion University of Thessalonika, Greece.

Purpose: The aim of this study was to determine the rates of incomplete excision of cervical intraepithelial neoplasia (CIN) III after carbon dioxide laser conization, and the risk of reappearance of CIN depending on the excision margins.

Methods: A total of 153 women who underwent carbon dioxide laser conization for CIN III between 1988 and 1998 at our hospitals were eligible for inclusion in the study and their notes were retrospectively studied.

Results: Histological examination of the excision margins revealed complete excision in 134 (87. Read More

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July 2002
4 Reads

Regular disappearance of the human papillomavirus genome after conization of cervical dysplasia by carbon dioxide laser.

Am J Obstet Gynecol 2000 Nov;183(5):1238-42

Department of Obstetrics and Gynecology, Umeâ University Hospital, Umeå, Sweden.

Objective: We wished to evaluate the effectiveness of treatment of cervical dysplasia by laser conization in relation to persistence of human papillomavirus after treatment.

Study Design: Of 203 women referred to colposcopy because of an abnormal Papanicolaou smear, 149 women could be followed up for 3 years. A total of 108 women were treated by carbon dioxide laser excision, 4 women were treated by carbon dioxide laser evaporation, and 37 women were merely followed up. Read More

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http://linkinghub.elsevier.com/retrieve/pii/S000293780092628
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http://dx.doi.org/10.1067/mob.2000.107322DOI Listing
November 2000
3 Reads

[Utilization of CO2 lasers in continuous or pulsed mode for conizations: apropos of 230 cases].

Gynecol Obstet Fertil 2000 Jul-Aug;28(7-8):537-46

Centre de lutte contre le cancer de Midi-Pyrénées, Toulouse, France.

Objective: A retrospective study with the aim of analysing efficiency, anatomical and functional consequences of a conservative methodology for the treatment of cervical intra-epithelial neoplasias (CIN) using carbon dioxide laser.

Materials And Method: Two hundred and thirty patients were treated and studied with an average waiting period of 38 months. During the study new methodology allowed a cut in the pulse regimen with adjustments in high energy levels. Read More

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October 2000
2 Reads

Treatment of vaginal dysplasia: just a simple loop electrosurgical excision procedure?

Am J Obstet Gynecol 2000 Mar;182(3):731-2

Department of Obstetrics and Gynecology, Coastal Area Health Education Center, New Hanover Regional Medical Center, Wilmington, NC 28402-9025, USA.

We report a case of sigmoid perforation, peritonitis, and adult respiratory distress syndrome after a loop excision procedure for carcinoma in situ of the cervix and dysplasia of the vagina. Treatment of vaginal dysplasia with loop excision is potentially dangerous. Safer methods of management include carbon dioxide laser, topical 5-fluorouracil, and fulguration. Read More

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March 2000
6 Reads

The use of carbon-dioxide laser surgery in the treatment of intraepithelial neoplasia of the uterine cervix.

Przegl Lek 1999 ;56(1):58-64

Department of Obstetrics and Gynecology, Spedali Civili University of Brescia, Italy.

From October 1989 to June 1997, 1841 patients (pts) suffering from different diseases of the lower genital tract have been treated with CO2 laser surgery in our Institution: among them, 782 were affected by cervical intraepithelial neoplasia (CIN). All pts underwent CO2 laser procedure for CIN after adequate colposcopic evaluation of the entire lower genital tract, colposcopic guided biopsy of the lesion, adequate pre-surgical work-up for possible infectious and coagulation associated disease. In 736 (94. Read More

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September 1999
5 Reads

Duration of pregnancy after carbon dioxide laser conization of the cervix: influence of cone height.

Obstet Gynecol 1997 Dec;90(6):978-82

Department of Obstetrics and Gynecology, Kantonsspital, Münsterlingen, Switzerland.

Objective: To determine if carbon dioxide laser conization of the cervix is a risk factor for preterm delivery in subsequent gestations and to evaluate whether there is any relationship between cone height and duration of pregnancy.

Methods: Patients of fertile age who had carbon dioxide laser conization were followed for reproductive events. Cases were matched one-to-one with controls for known risk factors for preterm delivery. Read More

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December 1997
3 Reads

Residual and recurrent disease after laser conization for cervical intraepithelial neoplasia.

Obstet Gynecol 1997 Sep;90(3):428-33

Department of Obstetrics and Gynecology, Medical Faculty, Norwegian University of Science and Technology, Trondheim, Norway.

Objective: To assess the risk of residual and recurrent disease after carbon dioxide laser conization treatment for high-grade lesions of the cervix uteri, and thus to refine intervals for follow-up.

Methods: The study population comprised all women treated for cervical intraepithelial neoplasia grade II-III over a 10-year period (1983-1992). All women who resided within the county for the entire follow-up period were followed for residual or recurrent disease, verified histologically until the closure date of January 31, 1996. Read More

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September 1997
1 Read

Treatment of penile intraepithelial neoplasia (PIN) with interferon alpha-2a, CO2 laser (vaporization) and 5-fluorouracil 5% (5-FU).

Eur J Gynaecol Oncol 1997 ;18(5):410-3

Department of Obstetrics and Gynecology, University of Patras, Rio, Greece.

This study was undertaken to assess the effectiveness of CO2 laser (vaporization), 5-FU topical application and Interferon (IFN alpha-2a) parenterally in the therapy of penile intraepithelial neoplasia (PIN). From March 1986 to September 1991, 1,372 men, sexual partners of women with condylomata accuminata or flat or cervical intraepithelial neoplasia (CIN), were submitted to peoscopy, of 1,019 men who presented with various lesions caused by human papillomavirus (HPV)-confirmed histologically-208 were treated for PIN. The best treatment modalities irrespective of grade of lesion were found to be the combination of 5-FU plus CO2 laser vaporisation plus IFN alpha-2a (high dose) (96. Read More

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November 1997
1 Read

Long-term follow-up of cervical intraepithelial neoplasia treated with minimal conization by carbon dioxide laser.

Authors:
Z Békássy

Lasers Surg Med 1997 ;20(4):461-6

Department of Obstetrics and Gynecology, University Hospital, Lund, Sweden.

Background And Objective: Minimal conization with carbon dioxide laser (CO2) for safe diagnosis and treatment of cervical intraepithelial neoplasia (CIN) 1-3 has been utilized for 15 years. To evaluate the results of 15 years' follow-up.

Study Design/materials And Methods: Clinical prospective study: 2,903 non-pregnant women whose cervicovaginal smear revealed CIN 1-3, confirmed by colposcopy, were referred for minimal conization treatment (LMC). Read More

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July 1997
1 Read

Laser miniconization procedure.

Authors:
Z Békássy

Int J Gynaecol Obstet 1996 Dec;55(3):237-46

Department of Obstetrics and Gynecology, University Hospital, Lund, Sweden.

Objective: To describe the outpatient procedure of minimal conization with free-hand guided high power density carbon dioxide laser for simultaneous diagnosis and treatment of CIN producing a one-piece tissue specimen for histological examination.

Material And Methods: 3100 non-pregnant patients with mild, moderate or severe dysplasia in pap smear, having colposcopically proved ectocervical lesions but without evidence of invasive carcinoma, or 85 pregnant patients with severe dysplasia in pap smear having extensive colposcopic signs of at least carcinoma in situ were admitted for this treatment. This outpatient procedure including cervical curettage is performed under local anesthesia to excise a one-piece 5 mm (during pregnancy 7 mm) deep minicone. Read More

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December 1996
1 Read

Treatment of men with flat (FC) or acuminata (CA) condylomata with interferon alpha-2a.

Eur J Gynaecol Oncol 1996 ;17(6):529-33

Euromedica Medical Center, Athens, Greece.

This study was undertaken to assess the effect of CO2 laser vaporization, 5-fluorouracil 5% (5-FU) topical application and Interferon alpha-2a (IFA alpha-2a) in the treatment of C.A. or F. Read More

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March 1997
1 Read

Laser "miniconisation' and the outcome of subsequent pregnancy.

Arch Gynecol Obstet 1996 ;258(2):75-9

Department of Obstetrics and Gynaecology, University of Lund, University Hospital, Sweden.

We routinely use the carbon dioxide laser miniconisation procedure for cervical interepithelial neoplasia I-III. A retrospective case control study was conducted in 1,485 miniconised women during 250 subsequent pregnancies (including three twin pregnancies). The analysis showed that the miniconised subjects had no significant pregnancy complications and the same preterm birth ratio (8. Read More

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September 1996
2 Reads

Management of patients with high grade squamous intraepithelial lesions.

Authors:
A Ferenczy

Cancer 1995 Nov;76(10 Suppl):1928-33

McGill University, Montreal, Quebec, Canada.

Background: The advent of modern electrosurgical equipment has allowed for outpatient excisional procedures rather than ablative therapy for patients with high grade squamous intraepithelial lesions (HGSILs).

Methods: The advantages and disadvantages of the commonly used ablative and excisional techniques for treatment of HGSILs were reviewed.

Results: Electrofulguration or cryotherapy for HGSILs smaller than 2. Read More

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November 1995
1 Read

Carbon dioxide laser miniconization for treatment of human papillomavirus infection associated with cervical intraepithelial neoplasia.

Acta Obstet Gynecol Scand 1995 Nov;74(10):822-6

Department of Obstetrics and Gynecology, Lund University Hospital, Sweden.

Background: The effect of the carbon dioxide laser miniconization for treatment of cervical intraepithelial neoplasia with concomitant human papillomavirus infection was evaluated.

Material And Methods: One hundred and eighteen women with cytologically proven cervical intraepithelial neoplasia stage 1 and/or 2 were investigated with repeat vaginal smear, colposcopy and human papillomavirus DNA sampling. Seventy-five out of 118 women were subjected to laser miniconization or punch biopsy and cervical curettage. Read More

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November 1995
7 Reads

The use of cervicography in the follow-up of cervical intraepithelial neoplasia treated by CO2 laser.

Aust N Z J Obstet Gynaecol 1995 Aug;35(3):349-50

Mercy Hospital for Women, Victoria.

After treatment for cervical intraepithelial neoplasia (CIN) the follow-up of patients would be simplified if colposcopy could be safely omitted. A study of 50 patients was performed to determine the feasibility of such an approach. Cervical cytology, cervicography and colposcopy, with or without biopsy, was performed in each patient. Read More

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August 1995
1 Read

Laser vaporization and excisional techniques in the treatment of cervical intraepithelial neoplasia.

Authors:
J M Monaghan

Baillieres Clin Obstet Gynaecol 1995 Mar;9(1):173-87

Queen Elizabeth Hospital, Gateshead, Tyne and Wear, UK.

The CO2 laser proved to be a vital tool in the development of conservative therapy for the treatment of CIN in the 1980s. In conjunction with colposcopy, the laser has allowed many women to achieve the security of identified and treated CIN with the freedom to live their lives normally, including the achievement of pregnancies. The laser may be used either in the ablative (vaporization) or the cutting mode. Read More

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March 1995
1 Read

Obstetrical prognosis for carbon dioxide laser conisation of the uterine cervix.

Eur J Obstet Gynecol Reprod Biol 1995 Jan;58(1):53-8

Fédération de Gynécologie-Obstétrique, Centre Hospitalier Régional Universitaire, Hopital Mère-Enfant, Nantes, France.

Carbon dioxide laser conisation is a very reliable surgical technique for cervical intraepithelial dysplasia. As cervical morphology and function are better preserved than with other techniques, obstetrical morbidity should be lower in the often young and pauciparous women who undergo this procedure. In our study comparing the course of 71 pregnancies (55 children) in 54 operated women with that of 82 pregnancies (59 children) in these same women before conisation, the rates for complications at the beginning of pregnancy were similar (respectively, 14. Read More

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January 1995
1 Read

Cervical intraepithelial neoplasia: carbon dioxide laser vaporization and conization. Our experience.

Eur J Gynaecol Oncol 1995 ;16(4):282-9

2nd Department of Obstetrics and Gynecology, University of Rome La Sapienza, Italy.

Between 1984 and 1992, the CO2 laser was used to treat 341 patients affected by CIN of various degrees. On the basis of specific indications these patients underwent vaporization or conization. Two hundred and twenty eight patients underwent vaporization of intraepithelial lesions, 221 (96. Read More

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November 1995

[CO2 laser in treatment of uterine cervix dysplasia in women with infertility].

Ginekol Pol 1994 Dec;65(12):690-4

Kliniki Rozrodczości, kierownik Kliniki.

The authors presented use of carbon dioxide laser in treatment of dysplasia of the uterine cervix in women with malreproduction. Between November 1991 and September 1993 in the Department of Reproduction, Institute of Gynecology and Obstetrics, Academy of Medicine, Poznań the CO2-laser vaporisation in 21 women was done. In 19 patients the healing was achieved. Read More

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December 1994
2 Reads

[The advantages of CO2 laser use in treatment of cervix dysplasia].

Geburtshilfe Frauenheilkd 1994 Jul;54(7):401-5

Frauenklinik der Heinrich-Heine-Universität Düsseldorf.

We use two kinds of laser treatment, namely, laser vaporisation and laser excision conisation. Laser vaporisation is a widely used method of localised ablative treatment based on both histologically confirmed cervical intraepithelial neoplasia and clear colposcopic visualisation of the upper limit of the lesion. Laser excision conisation is performed, if cervical intraepithelial neoplasia reaches the endocervix, being out of colposcopic view, and the squamocolumnar junction is localised in the endocervical canal. Read More

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http://dx.doi.org/10.1055/s-2007-1022866DOI Listing
July 1994
2 Reads

[Cervical intraepithelial neoplasia III treated with CO2 laser. Cytological, colposcopic and histopathological follow-up].

Ginecol Obstet Mex 1994 Apr;62:113-20

Hospital Regional Lic. Adolfo López Mateos, IMSS, México, D.F.

An study with 52 patients, was performed at the colposcopy Service, Hospital López Mateos, IMSS. The patients presented with an histological diagnosis of cervical in situ carcinoma. They were, previously, submitted to a colposcopic and cytological protocol study. Read More

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April 1994
1 Read

Pain evaluation during carbon dioxide laser vaporization for cervical intraepithelial neoplasia: a randomized trial.

Clin Exp Obstet Gynecol 1994 ;21(3):188-91

II Clinic of Obstetrics and Gynecology, University of Rome La Sapienza.

63 pts affected by CIN of various degrees were randomly divided into 3 groups in order to evaluate the pain experienced during laser vaporization of the lesion. All pts were premenopausal and ages ranged between 19 and 39 years. 21 pts received Naproxene Sodium (550 mg) 30 minutes before surgery; 21 pts received placebo and 21 pts received no drug. Read More

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October 1994
2 Reads

A randomized trial of laser vaporization in the management of cervical intraepithelial neoplasia associated with human papilloma virus infection.

J Public Health Med 1993 Dec;15(4):327-31

Centre for Cancer Epidemiology, Withington, Manchester.

A randomized controlled trial was carried out at colposcopy clinics in the Birmingham and Midland Hospital for Women, to determine the efficacy of laser vaporization in the management of cervical Human Papilloma Virus (HPV) infection occurring alone or in association with cervical intraepithelial neoplasia (CIN), and to study the natural history of these lesions. The subjects were 365 women referred for investigation of cytological abnormality who were found to have histological evidence of HPV infection alone or in association with CIN1 or CIN2 and were considered suitable for local destructive treatment. The intervention consisted of immediate treatment using a carbon dioxide laser or no treatment. Read More

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December 1993
2 Reads

Outpatient surgery in gynecologic oncology.

Curr Opin Obstet Gynecol 1993 Jun;5(3):318-21

Division of Obstetric and Gynecologic Pathology and Cytology, Sloane Hospital for Women, New York, NY 10032.

There has been an enormous change in outpatient-directed surgery for human papillomavirus-related lesions of the anogenital tract over the past 2 years. Concern that a small number of invasive cancers were being missed during evaluation and were being treated as precursors led many investigators to suggest excisional rather than ablative procedures for precursor management. The use of cold-knife or carbon dioxide laser excisions was recommend as the procedure of choice--particularly for high-grade cervical intraepithelial neoplasia lesions. Read More

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June 1993
1 Read

Outpatient CO2 laser excisional conization for cervical intraepithelial neoplasia under local anesthesia.

Acta Obstet Gynecol Scand 1993 May;72(4):302-6

Department of Obstetrics and Gynecology, Central Hospital Naestved, Denmark.

Aim And Objective: To evaluate the feasibility of CO2 laser excisional conization in patients with cervical intraepithelial neoplasia (CIN) in an outpatient setting under local anesthesia.

Design: A prospective study of women with cervical intraepithelial neoplasia over one year recording early and late complications, cure rate, and patients' compliance. The procedure was performed with a Coherent CO2 laser connected to the colposcope with a micromanipulator. Read More

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May 1993
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Outpatient excisional management of cervical intraepithelial neoplasia. A prospective, randomized comparison between loop diathermy excision and laser excisional conization.

Am J Obstet Gynecol 1993 Feb;168(2):485-8

Central Middlesex Hospital, London, England.

Objective: The purpose of our study was to compare loop diathermy excision and laser excisional conization with respect to treatment time, reliability, effectiveness, and safety.

Study Design: Three hundred women with cervical intraepithelial neoplasia attending our colposcopy clinic were randomized to treatment with either loop diathermy excision (group 1, n = 150) or carbon dioxide laser excisional conization (group 2, n = 150), both performed with local anesthesia on an outpatient basis. Student's t or Mann-Whitney test were used to compare continuous data; the chi 2 test was used for categoric data. Read More

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February 1993
2 Reads

Carbon dioxide laser treatment of cervical dysplasia in teenagers.

Eur J Obstet Gynecol Reprod Biol 1992 Sep;46(2-3):143-6

Department of Gynecology, Obstetrics and Reproduction Biology, Nantes University Hospital, France.

Over a 6-year period, 40 young women under 20 years of age with cervical intraepithelial neoplasia (CIN) grade I (58%) to grade III (10%) were treated by laser vaporisation or excisional conisation. This prevalence of CIN in young women (nearly 4% of laser-treated cases) underscores the need for detection of cervical abnormalities in all teenagers engaged in sexual relations. The colposcopically-guided carbon dioxide laser technique is the treatment of choice for vaporisation and conisation of intraepithelial lesions (extending to the periphery of the cervix in 20% of cases) and for vaporisation of associated condylomatous lesions of the cervix (75%), vagina (23%), vulva (48%) and/or anus (8%). Read More

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September 1992
2 Reads

Conization with a carbon dioxide laser as a uterine-preservation operation for patients with preinvasive cervical carcinoma.

J Formos Med Assoc 1992 May;91(5):521-5

Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, R.O.C.

Preinvasive cervical carcinoma (PCC) is a disease entity of the uterine cervix resulting from carcinoma in situ and various degrees of dysplasia. These cases are conventionally treated by a total abdominal hysterectomy. Effective management that can preserve the uterus is more desirable than hysterectomy. Read More

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May 1992
2 Reads

Carbon dioxide laser surgery in colposcopy for cervicovaginal intraepithelial neoplasia treatment. 10 years experience and failure analysis.

Eur J Gynaecol Oncol 1992 ;13(1 Suppl):78-81

Dept. B, University of Turin.

CO2 laser vaporisation is an effective method in the treatment of cervico-vaginal pre-invasive lesions. In a case-series of 334 patients no case of invasive neoplasia development were registered at longterm follow-up. The failure rate is comparable to those described with traditional surgical methods and are due to the particular topography of the disease. Read More

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September 1992
3 Reads