Front Microbiol 2021 7;12:692491. Epub 2021 Jun 7.
Department of Surgical, Medical, Dental and Morphological Sciences with Interest in Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Vulvovaginal candidiasis (VVC) is a symptomatic inflammation of the vagina mainly caused by . Other species, such as , , , and , are mainly associated to the recurrent form of the disease (RVVC), although with a lower frequency. In its yeast form, is tolerated by the vaginal epithelium, but switching to the invasive hyphal form, co-regulated with the expression of genes encoding virulence factors such as secreted aspartyl proteases (Sap) and candidalysin, allows for tissue damage. Read More