4 results match your criteria Cancer reports and reviews[Journal]

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Extent of diagnostic inquiry among a population-based cohort of patients with cancer of unknown primary.

Cancer Rep Rev 2019 Sep 8;3(3). Epub 2019 Jul 8.

University of Miami School of Medicine, Public Health Sciences, Miami, Florida, USA.

Purpose: Current cancer registry data cannot distinguish a justified cancer of unknown primary (CUP) diagnosis, where the patient received a complete diagnostic evaluation that was unable to identify the primary tumor, from potentially misclassified patients, documented as CUP but not based on a complete diagnostic evaluation. This misclassification may skew population-based cancer registry surveillance research used to frame and guide translational CUP research. We identified characteristics of patients who received justified vs. Read More

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http://dx.doi.org/10.15761/CRR.1000187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905506PMC
September 2019

Aberrant expression of ETS1 and ETS2 proteins in cancer.

Cancer Rep Rev 2018 23;2(3). Epub 2018 Apr 23.

The Dept. of Pathology, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157 USA.

The ETS transcription factors regulate expression of genes involved in normal cell development, proliferation, differentiation, angiogenesis, and apoptosis, consisting of 28 family members in humans. Dysregulation of these transcription factors facilitates cell proliferation in cancers, and several members participate in invasion and metastasis by activating gene transcription. ETS1 and ETS2 are the founding members of the ETS family and regulate transcription by binding to ETS sequences. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027756PMC
http://dx.doi.org/10.15761/CRR.1000151DOI Listing
April 2018
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Aberrant expression of p16 in human cancers - a new biomarker?

Cancer Rep Rev 2018 Mar 15;2(2). Epub 2018 Jan 15.

The Department of Pathology, Wake Forest University Health Sciences, Winston-Salem, NC 27157.

The and genes are located in the same locus, both showing its tumor suppressive activity. ARF has been shown to detect potentially harmful oncogenic signals, making incipient cancer cells undergo senescence or apoptosis. INK4a, on the other hand, responds to signals from aging in a variety of tissues including islets of Langerhans, neuronal cells, and cancer stem cells in general. Read More

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http://www.oatext.com/aberrant-expression-of-p16ink4a-in-hum
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018005PMC
http://dx.doi.org/10.15761/CRR.1000145DOI Listing
March 2018
4 Reads

The Histogenesis of Ewing Sarcoma.

Cancer Rep Rev 2017 7;1(2). Epub 2017 Feb 7.

Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.

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http://oatext.com/The-histogenesis-of-Ewing-Sarcoma.php
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472389PMC
http://dx.doi.org/10.15761/CRR.1000111DOI Listing
February 2017
14 Reads
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