41,471 results match your criteria Cancer and Rehabilitation


Questionnaire-based somatosensory profiling in breast cancer survivors: are we there yet? Associations between questionnaires and quantitative sensory testing.

Disabil Rehabil 2022 May 26:1-12. Epub 2022 May 26.

Department of Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Sciences, MOVANT, University of Antwerp, Antwerp, Belgium.

Purpose: Pain and sensory disturbances are common side effects of breast cancer treatment. Differential somatosensory functioning may reflect distinct pathophysiological backgrounds and therapeutic needs. Aim was to examine whether questionnaires evaluating signs and symptoms related to somatosensory functioning correlate sufficiently with quantitative sensory testing (QST) in breast cancer survivors to warrant consideration for somatosensory profiling in clinical practice. Read More

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Ethnocultural Minority Workers and Sustainable Return to Work Following Work Disability: A Qualitative Interpretive Description Study.

J Occup Rehabil 2022 May 26. Epub 2022 May 26.

Centre d'action en Prévention et Réadaptation des Incapacités au Travail (CAPRIT), Université de Sherbrooke, 150 Place Charles-Le Moyne, Suite 200, Longueuil, QC, J4K 0A8, Canada.

Purpose This article provides a state-of-the-art review of issues and factors associated with the sustainable return to work (S-RTW) of ethnocultural minority workers experiencing disability situations attributable to one of four major causes: musculoskeletal disorders, common mental disorders, other chronic diseases or cancer. Methods Using an interpretive description method, an integrative review was conducted of the literature on ethnocultural factors influencing S-RTW issues and factors associated with these four major work-disability causes. An initial review of the 2006-2016 literature was subsequently updated for November 2016-May 2021. Read More

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Effect of Somatosensory Interaction Transcutaneous Electrical Acupoint Stimulation on Cancer-related Fatigue and Immunity: A Randomized Controlled Trial.

Am J Clin Oncol 2022 May 26. Epub 2022 May 26.

Nursing Department, Department of Head and Neck Surgery, Otolaryngology & Head and Neck Center, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College).

Background: This study was intended to evaluate the clinical effect of somatosensory interaction transcutaneous electrical acupoint stimulation (SI-TEAS) on cancer-related fatigue (CRF) and its safety.

Methods: The study protocol had been registered in China Clinical Trial Registration Center with registration number: ChiCTR2100045655. CRF patients were equally divided into SI-TEAS Group, Acupressure Group and Sham Acupressure Group to receive SI-TEAS, acupressure and sham acupressure treatments 5 times a week. Read More

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When experiencing a surgery: Gastrointestinal cancer patients' longitudinal trajectories in psychological stress and their association with quality of recovery.

Asia Pac J Oncol Nurs 2022 Jun 11;9(6):100064. Epub 2022 Apr 11.

Department of Health Psychology, School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, China.

Objective: Surgical treatment, particularly for gastrointestinal cancer, is a burdensome prospect for many patients. Psychological stress is a common complaint; however, little is known about its patterns in perioperative patients. This study aimed to identify distinct trajectories of perioperative stress and explore antecedent factors and hospitalization outcomes among different trajectories in patients with gastrointestinal cancer. Read More

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Rehabilitation Including Structured Active Play for Preschoolers With Cancer (RePlay)-Study Protocol for a Randomized Controlled Trial.

Front Pediatr 2022 9;10:834512. Epub 2022 May 9.

Department for Pediatrics and Adolescent Medicine, The Juliane Marie Center, Copenhagen University Hospital, Copenhagen, Denmark.

Background: Children diagnosed with cancer experience muscle weakness and impaired physical function caused by treatment and related immobility. The situation forces them into a negative cycle of diminished participation in physical and leisure activities and isolation from peers; inhibiting the natural development of social and gross motor skills. This manuscript presents a protocol for a study that explores the effects of using structured active play to maintain preschoolers' age specific gross motor function and social and personal skills while undertaking intensive cancer treatment. Read More

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Overexpression of TP53INP2 Promotes Apoptosis in Clear Cell Renal Cell Cancer via Caspase-8/TRAF6 Signaling Pathway.

J Immunol Res 2022 14;2022:1260423. Epub 2022 May 14.

Department of Rehabilitation Medicine, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.

Clear cell renal cell cancer (ccRCC) is a tumor of high malignancy, which can escape apoptosis. The tumor protein p53-inducible nuclear protein 2 (TP53INP2), known as an autophagy protein, is the essential part for autophagosome formation and sensitizes cells to apoptosis. Our study is aimed at exploring the role of TP53INP2 in ccRCC. Read More

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Usability, acceptability, and implementation strategies for the Exercise in Cancer Evaluation and Decision Support (EXCEEDS) algorithm: a Delphi study.

Support Care Cancer 2022 May 26. Epub 2022 May 26.

Department of Occupational Therapy, Colorado State University, Fort Collins, CO, USA.

Introduction: Oncology guidelines recommend participation in cancer rehabilitation or exercise services (CR/ES) to optimize survivorship. Yet, connecting the right survivor, with the right CR/ES, at the right time remains a challenge. The Exercise in Cancer Evaluation and Decision Support (EXCEEDS) algorithm was developed to enhance CR/ES clinical decision-making and facilitate access to CR/ES. Read More

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Development of a functional assessment task in metastatic breast cancer patients: the 30-second lie-to-sit test.

Disabil Rehabil 2022 May 24:1-8. Epub 2022 May 24.

Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain.

Purpose: To develop a physical function test based on lie-to-sit transition and to study its feasibility in patients suffering from metastatic breast cancer (MBC).

Materials And Methods: This cross-sectional study recruited 90 women diagnosed with MBC. Patients were asked to transfer from lying to sitting position as fast as possible during 30 s, performing the 30-second lie-to-sit test (30-LTS). Read More

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Disease-specific Nutritional Physical Therapy: A Position Paper by the Japanese Association of Rehabilitation Nutrition (Secondary Publication).

JMA J 2022 Apr 25;5(2):252-262. Epub 2022 Mar 25.

Department of Rehabilitation Medicine, Tokyo Women's Medical University Graduate School of Medicine, Tokyo, Japan.

Nutritional disorders diminish the effectiveness of physical therapy. The pathogenesis of nutritional disorders, such as sarcopenia, frailty, and cachexia, differs from disease to disease. Disease-specific nutrition can maximize the function, activity, participation, and quality of life for patients undergoing physical therapy, a practice known as nutritional physical therapy. Read More

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FXR expression in rats of hilar cholangiocarcinoma.

Sci Rep 2022 May 24;12(1):8741. Epub 2022 May 24.

Department of Rehabilitation, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan Province, China.

The study objective was to detect the expression of farnesoid X receptor (FXR) in a rat model of hilar cholangiocarcinoma to provide a new therapeutic target for gene therapy in hilar cholangiocarcinoma. Sixty male Wistar rats (weighing 190 ± 8 g) were randomly divided into three groups (experimental group, control group and sham operation group, 20 rats in each group). The three groups were fed a standard diet. Read More

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Intensive physical therapy after emergency laparotomy: Pilot phase of the Incidence of Complications following Emergency Abdominal surgery Get Exercising randomized controlled trial.

J Trauma Acute Care Surg 2022 Jun 18;92(6):1020-1030. Epub 2022 Jan 18.

From the School of Medicine (I.B.), University of Tasmania, Launceston, Tasmania, Australia; Physical Therapy Department (I.B., K.S.), Launceston General Hospital, Launceston, Tasmania; Department of Physical Therapy (I.B., C.H., L.D.), The University of Melbourne, Melbourne; Faculty of Nursing, Medicine and Health Science (K.S.), School of Primary Health Care, Monash University, Frankston, Victoria; Department of Physical Therapy (C.H., R.H.), Princess Alexandra Hospital, Woolloongabba, Queensland; Physical therapy Department (B.W.), Northeast Health Wangaratta, Wangaratta, Victoria; Anaesthesia Perioperative and Pain Medicine Unit (D.S.), The University of Melbourne; Melbourne Clinical and Translational Science Research Platform (D.S.); and Peter McCallum Cancer Centre (L.D.), Allied Health Research, Melbourne, Australia.

Background: Postoperative pneumonia and delayed physical recovery are significant problems after emergency laparotomy. No randomized controlled trial has assessed the feasibility, safety, or effectiveness of intensive postoperative physical therapy in this high-risk acute population.

Methods: The internal pilot phase of the Incidence of Complications after Emergency Abdominal Surgery: Get Exercising (ICEAGE) trial was a prospective, randomized controlled trial that evaluated the feasibility, safety, and clinical trial processes of providing intensive physical therapy immediately following emergency laparotomy. Read More

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Academic and Employment Status in Patients With Generalized Myasthenia Gravis Treated With Eculizumab: A Case Series.

J Clin Neuromuscul Dis 2022 Jun;23(4):210-218

Department of Neurology, University of Missouri Health Care, Columbia, MO.

Objectives: To evaluate the impact of treatment with eculizumab, a terminal complement inhibitor, on academic and employment status in patients with refractory generalized myasthenia gravis (MG).

Methods: Case review of 7 US patients.

Results: Six patients were aged ≤65 years; one was a full-time student and the remainder were in employment before MG diagnosis. Read More

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Electroacupuncture for Cancer-Related Cognitive Impairment: A Clinical Feasibility Study.

Integr Cancer Ther 2022 Jan-Dec;21:15347354221098983

Sangji University, Wonju, Gangwon-do, Republic of Korea.

Background: Cancer-related cognitive impairment (CRCI) is a significant problem for cancer patients, as the number of cancer survivors experiencing cognitive impairments is increasing in the absence of standard treatment. There have been attempts to improve the cognitive function of patients with cancer using acupuncture; however, no studies have been conducted using electroacupuncture. Thus, we designed a preliminary study to investigate the feasibility of a clinical trial using electroacupuncture in CRCI patients. Read More

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Humoral and T-cell immune response after three doses of mRNA SARS-CoV-2 vaccines in fragile patients: the Italian VAX4FRAIL study.

Clin Infect Dis 2022 May 24. Epub 2022 May 24.

Scientific Directorate, Azienda Unità Sanitaria Locale (USL)-IRCCS Reggio Emilia, Reggio Emilia, Italy.

Background: Patients with solid or hematological tumors, neurological and immune-inflammatory disorders are potentially fragile subjects at increased risk of experiencing severe COVID-19 and an inadequate response to SARS-CoV-2 vaccination.

Methods: We designed a prospective Italian multicentrer study to assess humoral and T-cell responses to SARS-CoV-2 vaccination in patients (n = 378) with solid tumors (ST), hematological malignancies (HM), neurological disorders (ND) and immunorheumatological diseases (ID). A group of healthy controls was also included. Read More

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Prognostic Value of Immunotyping Combined with Targeted Therapy in Patients with Non-Small-Cell Lung Cancer and Establishment of Nomogram Model.

Comput Math Methods Med 2022 14;2022:3049619. Epub 2022 May 14.

Department of Internal Medicine, College of Integrated Chinese and Western Medicine, Hunan University of Chinese Medicine, China.

Objective: Bioinformatics methods were used to analyze non-small-cell lung cancer gene chip data, screen differentially expressed genes (DEGs), explore biomarkers related to NSCLC prognosis, provide new targets for the treatment of NSCLC, and build immunotyping and line-map model.

Methods: NSCLC-related gene chip data were downloaded from the GEO database, and the common DEGs of the two datasets were screened by using the GEO2R tool and FunRich 3.1. Read More

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[NOT ONLY FOR CANCER PATIENTS - PALLIATIVE CARE FOR NON-ONCOLOGIC PATIENTS AT THE END OF LIFE IN A GERIATRIC - INTERNAL MEDICINE DEPARTMENT].

Harefuah 2022 May;161(5):322-326

Geriatric Division, Tel Aviv Souraski Medical Center.

Aims: This article presents our ongoing experience in the care of palliative patients suffering from non-oncologic diseases.

Background: Palliative care is an approach intended to improve quality of life in patients facing life-threatening illness. This approach entails early identification, thorough assessment and treatment of pain and suffering as well as establishing a goals-directed care plan in order to improve these patients' quality of life. Read More

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The prognostic value of the preoperative inflammatory index on the survival of glioblastoma patients.

Neurol Sci 2022 May 23. Epub 2022 May 23.

Department of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute, Cheeloo College of Medicine, Shandong University, Wenhua Xi Road, Jinan, 250012, China.

Objectives: The growth and development of tumors are closely related to the initiation and amplification of the inflammatory response. Various inflammatory biomarkers had attained growing attention for nearly two decades and were discovered strongly associated with cancer patients' prognosis, indicating that systemic inflammatory response is possibly essential to cancer progression. However, little was known about the sensitive biomarkers associated with the detection, persistence, treatment, and prognosis of GBM. Read More

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Swallowing function improvement using costal cartilage for severe dysphagia after supracricoid hemilaryngopharyngectomy.

Auris Nasus Larynx 2022 May 20. Epub 2022 May 20.

Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.

Supracricoid hemilaryngopharyngectomy (SCHLP) is a laryngeal preservation surgery for hypopharyngeal carcinoma confined to the pyriform sinus or laryngeal carcinoma with arytenoid infiltration. Postoperative dysphagia is inevitable, but both voice and swallowing functions can be preserved. Here, we present a case of severe dysphagia secondary to unexpected postoperative tissue loss and scarring. Read More

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Hydrogel-based co-delivery of CIK cells and oncolytic adenovirus armed with IL12 and IL15 for cancer immunotherapy.

Biomed Pharmacother 2022 May 20;151:113110. Epub 2022 May 20.

Department of Rehabilitation, School of Nursing, Jilin University, Changchun 130021, PR China. Electronic address:

Intratumoral injection of various effector cells combined with oncolytic adenovirus expressing antitumor cytokines exert an effective antitumor immune effect by oncolysis and altering the tumor microenvironment. However, this combination therapy had certain limitations. When used in high concentrations, effector cells and oncolytic viruses can spread rapidly to surrounding non-target tissues. Read More

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The Impact of a Nurse-Led Exercise Activity for Cancer-Related Fatigue in Patients With Leukemia.

Authors:
Laura Galunas

Clin J Oncol Nurs 2022 Jun;26(3):257-260

University of Michigan.

Many patients with leukemia experience cancer-related fatigue (CRF). However, when patients are admitted for treatment with chemotherapy, clinicians often overlook CRF and interventions that can help to manage it. The purpose of this four-week intervention was to determine whether a nurse-led exercise activity would reduce CRF and increase physical activity compared to current practice. Read More

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Illness perception profiles and psychological and physical symptoms in newly diagnosed advanced non-small cell lung cancer.

Health Psychol 2022 Jun;41(6):379-388

Department of Psychology, The Ohio State University.

Objective: Of all cancers, advanced nonsmall cell lung cancer (NSCLC) is associated with the highest burden on mental and physical health-related quality of life (HRQoL). Patients' subjective beliefs about their cancer (i.e. Read More

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The Attenuated Pseudorabies Virus Vaccine Strain Bartha Hyperactivates Plasmacytoid Dendritic Cells by Generating Large Amounts of Cell-Free Virus in Infected Epithelial Cells.

J Virol 2022 May 23:e0219921. Epub 2022 May 23.

Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent Universitygrid.5342.0, Ghent, Belgium.

Pseudorabies virus (PRV) is a porcine alphaherpesvirus and the causative agent of Aujeszky's disease. Successful eradication campaigns against PRV have largely relied on the use of potent PRV vaccines. The live attenuated Bartha strain, which was produced by serial passaging in cell culture, represents one of the hallmark PRV vaccines. Read More

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Optimization of endometrial cancer organoids establishment by cancer-associated fibroblasts.

Neoplasma 2022 May 23. Epub 2022 May 23.

Department of Obstetrics and Gynecology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

Most endometrial cancers (EC) are diagnosed at an early stage with a favorable prognosis. However, for patients with advanced or recurrent disease, the chemotherapy response rate and overall survival remain poor. A novel in vitro model, tumor organoids, has important value in providing a more individualized treatment plan for tumor patients. Read More

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Scoping review of music therapy and music interventions in spinal cord injury.

Disabil Rehabil 2022 May 21:1-14. Epub 2022 May 21.

Department of Clinical Neurosciences, Division of Physical Medicine and Rehabilitation, University of Calgary, Calgary, AB, Canada.

Purpose: Spinal cord injury (SCI) has lifelong implications requiring treatment for outcomes including respiratory function, voice, pain, mood, and gait, among others. Music therapy (MT) and music-based interventions may be useful in the treatment of several outcomes. This review describes the use of MT and music-based interventions in individuals with SCI for rehabilitation and health and highlights future research priorities. Read More

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Salivary Xanthine Oxidase as a Potential Biomarker in Stroke Diagnostics.

Front Immunol 2022 6;13:897413. Epub 2022 May 6.

Department of Risk Group Dentistry, Chair of Pediatric Dentistry, Poznan University of Medical Sciences, Poznan, Poland.

Stroke is one of the most common cerebrovascular diseases. Despite significant progress in understanding stroke pathogenesis, cases are still increasing. Thus, laboratory biomarkers of stroke are sought to allow rapid and non-invasive diagnostics. Read More

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Psychometric Properties of the Persian Version of Palliative Care Outcome Scale (POS) in Adult Patients With Cancer.

Front Psychol 2022 28;13:858684. Epub 2022 Apr 28.

Health Management Research Center, Nursing Faculty, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Background: Measuring the outcomes of palliative care plays an important role to improve the quality, efficiency, and availability of these services in patients with cancer. Using valid, reliable, and culturally appropriate tools has a considerable role to measure these outcomes. This study aimed to assess the psychometric properties of the translated version of the Palliative care Outcome Scale (POS). Read More

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Nursing Effect and Prognosis Analysis of Self-Management Education Model Based on Protective Motivation Theory on Patients with Hematological Tumor after PICC Catheterization.

Comput Math Methods Med 2022 13;2022:4180113. Epub 2022 May 13.

Department of Hematology-Oncology, The Children's Hospital, Zhejiang University School of Medicine, Pediatric Leukemia Diagnostic and Therapeutic Technology Research Center of Zhejiang Province, National Clinical Research Center for Child Health, Hangzhou 310000, China.

Objective: To analyze the nursing effect and prognostic value of self-management education model based on protective motivation theory on patients with hematological malignancies (HM) after peripheral venous catheterization (PICC).

Methods: A total of 90 patients with HMs treated with PICC catheterization in our hospital from October 2019 to October 2021 were included in the study. The patients were randomly assigned into experimental group ( = 45) and control group ( = 45). Read More

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Development of a Risk Score Model for Osteosarcoma Based on DNA Methylation-Driven Differentially Expressed Genes.

J Oncol 2022 13;2022:7596122. Epub 2022 May 13.

Department of Minimally Invasive Spine Surgery, Tianjin Hospital, Tianjin, China.

Osteosarcoma (OS) is the commonest malignant bone tumor in adolescent patients, and patients face amputation, tumor metastasis, chemotherapy resistance, and even death. We investigated the potential connection between abnormal methylation differentially expressed genes and the survival rate of osteosarcoma patients. GSE36002 and GSE12865 datasets of GEO database were utilized for abnormal methylation differentially expressed genes, followed by function and pathway enrichment analyses, the protein-protein interaction network in the STRING database, and cluster analysis in the MCODE app of Cytoscape. Read More

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