29,954 results match your criteria Cancer and Rehabilitation


The beneficial roles of exercise training via autophagy in neurological diseases and possible mechanisms.

Life Sci 2019 Feb 12. Epub 2019 Feb 12.

Department of Rehabilitation Medicine, The Third Hospital of Hebei Medical University, Shijiazhuang 050051, PR China; Hebei Provincial Orthopedic Biomechanics key laboratory,The Third Hospital of Hebei Medical University, Shijiazhuang 050051, PR China. Electronic address:

Autophagy is a conservative catabolism process, participating in delivering the cytosol and cytosolic components to the lysosome. Abnormal autophagy is related to human pathologies, for instance diabetes, neurodegeneration, cardiovascular, macular degeneration, pulmonary, and cancer. Enormous evidences indicate that autophagy may mediate the cellular pathological condition in the process of neurological diseases. Read More

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http://dx.doi.org/10.1016/j.lfs.2019.02.026DOI Listing
February 2019
1 Read

Assessment of quality of life, information, and supportive care needs in patients with muscle and non-muscle invasive bladder cancer across the illness trajectory.

Support Care Cancer 2019 Feb 14. Epub 2019 Feb 14.

Cancer Rehabilitation and Survivorship Program, Princess Margaret Cancer Centre, Toronto, Canada.

Background: To date, little research has examined the quality of life and cancer-associated needs of bladder cancer patients. The objective of the current study was to assess the quality of life (QoL), informational needs, and supportive care needs (SCN) in a large sample of muscle invasive (MIBC) and non-muscle invasive (NMIBC) bladder cancer survivors across the treatment trajectory (newly diagnosed and undergoing treatment, post-treatment follow-up, and treatment for advanced/recurrent disease).

Methods: Questionnaires were distributed to a convenience sample of patients registered with Bladder Cancer Canada, the Princess Margaret Cancer Centre, or The Ottawa Hospital. Read More

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http://dx.doi.org/10.1007/s00520-019-4649-zDOI Listing
February 2019

How is patient-centred care addressed in women's health? A theoretical rapid review.

BMJ Open 2019 Feb 13;9(2):e026121. Epub 2019 Feb 13.

Louise Temerty Breast Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

Purpose: Efforts are needed to reduce gendered inequities and improve health and well-being for women. Patient-centred care (PCC), an approach that informs and engages patients in their own health, is positively associated with improved care delivery, experiences and outcomes. This study aimed to describe how PCC for women (PCCW) has been conceptualised in research. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-026121DOI Listing
February 2019
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Predicting outcomes following holistic breathlessness services: A pooled analysis of individual patient data.

Palliat Med 2019 Feb 15:269216319830299. Epub 2019 Feb 15.

1 Cicely Saunders Institute of Palliative Care, Policy & Rehabilitation, King's College London, London, UK.

Background:: Holistic breathlessness services have been developed for people with advanced disease and chronic breathlessness, leading to improved psychological aspects of breathlessness and health. The extent to which patient characteristics influence outcomes is unclear.

Aim:: To identify patient characteristics predicting outcomes of mastery and distress due to breathlessness following holistic breathlessness services. Read More

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http://dx.doi.org/10.1177/0269216319830299DOI Listing
February 2019

A systematic review and network meta-analysis protocol of adjuvant chemotherapy regimens for resected gastric cancer.

Medicine (Baltimore) 2019 Feb;98(7):e14478

The First Clinical Medical College.

Background: Gastric cancer is the third leading cause of cancer death in the world. The benefit of adjuvant chemotherapy has been demonstrated by published individual patient data meta-analysis and Cochrane systematic review. However, there is no consensus on which is the optimal adjuvant chemotherapy regimens. Read More

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http://dx.doi.org/10.1097/MD.0000000000014478DOI Listing
February 2019

Localized Corticosteroid Injections for Malignant Joint Pain in the Oncologic Population: A Case Series.

A A Pract 2019 Feb 7. Epub 2019 Feb 7.

Department of Anesthesiology and Critical Care, Memorial Sloan Kettering Cancer Center, New York, New York.

Pain is a common issue that is present in cancer survivors as well as those with active malignant processes. Despite opioid analgesics and adjuvant therapies such as systemic corticosteroids, many patients have persistent localized pain. We describe a case series of 3 cancer patients who have concurrent hip- and greater trochanteric-related pain. Read More

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http://dx.doi.org/10.1213/XAA.0000000000000977DOI Listing
February 2019

Citation analysis of the most influential articles on traumatic spinal cord injury.

J Spinal Cord Med 2019 Feb 14:1-8. Epub 2019 Feb 14.

a Department of Neurological Surgery , University of Pittsburgh Medical Center , Pittsburgh , Pennsylvania , USA.

Objective: We conducted a citation analysis in order to catalog and pay tribute to the 100 most influential clinical research articles in traumatic spinal cord injury.

Design: The Thomson Reuters Web of Science was searched in a two-step process without time period limitations. Review articles were excluded. Read More

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http://dx.doi.org/10.1080/10790268.2019.1576426DOI Listing
February 2019

Reciprocal Regulation Between O-GlcNAcylation and β-Catenin Facilitates Cell Viability and Inhibits Apoptosis in Liver Cancer.

DNA Cell Biol 2019 Feb 14. Epub 2019 Feb 14.

1 Department of Hepatology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, P.R. China.

Abnormal expression of O-Linked β-N-acetylglucosamine (O-GlcNAc) and β-catenin is a general feature of cancer and contributes to transformed phenotypes. In this study, we identified the interaction between O-GlcNAc and β-catenin, and explored their effects on the progression of liver cancer. Our results demonstrated that upregulation of O-GlcNAc was induced by high glucose, whereas the application of PuGNAc and GlcNAc increased β-catenin protein expression levels, as well as the protein's stability and nuclear accumulation in the liver cancer cell lines HEP-G2 and HuH-7. Read More

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http://dx.doi.org/10.1089/dna.2018.4447DOI Listing
February 2019

Role of Sonification and Rhythmic Auditory Cueing for Enhancing Gait Associated Deficits Induced by Neurotoxic Cancer Therapies: A Perspective on Auditory Neuroprosthetics.

Front Neurol 2019 29;10:21. Epub 2019 Jan 29.

Consultation Division, Program Management Discovery Sciences, RSGBIOGEN, New Delhi, India.

Patients undergoing chemotherapy, radiotherapy, and immunotherapy experience neurotoxic changes in the central and peripheral nervous system. These neurotoxic changes adversely affect functioning in the sensory, motor, and cognitive domains. Thereby, considerably affecting autonomic activities like gait and posture. Read More

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http://dx.doi.org/10.3389/fneur.2019.00021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361827PMC
January 2019

Antidepressant Effects of Repetitive Transcranial Magnetic Stimulation Over Prefrontal Cortex of Parkinson's Disease Patients With Depression: A Meta-Analysis.

Front Psychiatry 2018 29;9:769. Epub 2019 Jan 29.

Department of Radiology and Imaging Institute of Rehabilitation and Development of Brain Function, The Second Clinical Medical College of North Sichuan Medical College Nanchong Central Hospital, Nanchong, China.

The purpose of this meta-analysis was to investigate the antidepressant effects of repetitive transcranial magnetic stimulation (rTMS) over the prefrontal cortex (PFC) of patients with Parkinson's disease (PD) and to determine the optimal rTMS parameters, such as the intensity, frequency and the delivered pattern of rTMS stimulation. EMBASE, PubMed, Web of Science, MEDLINE, and Cochrane data bases were researched for papers published before March 12, 2018. Studies investigating the anti-depression effects of rTMS over PFC in patients with PD were considered. Read More

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http://dx.doi.org/10.3389/fpsyt.2018.00769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362497PMC
January 2019

Antitumor potential of new low molecular weight antioxidative preparations from the white rot fungus Cerrena unicolor against human colon cancer cells.

Sci Rep 2019 Feb 13;9(1):1975. Epub 2019 Feb 13.

Department of Biochemistry, Maria Curie-Skłodowska University, Lublin, Poland.

The aim of this study was to investigate the anticancer and antioxidant activities of low molecular weight subfractions isolated from secondary metabolites produced by the wood degrading fungus Cerrena unicolor. Human colon cancer cells (stage I) HT-29 and human normal colon epithelial cells CCD 841 CoTr were used in the research. The present study demonstrated that the low molecular weight subfractions exhibited inhibitory activity towards human colon cancer cells HT-29 at a concentration range of 25-200 μg/mL. Read More

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http://dx.doi.org/10.1038/s41598-018-37947-zDOI Listing
February 2019

Mimicry and well known genetic friends: molecular diagnosis in an Iranian cohort of suspected Bartter syndrome and proposition of an algorithm for clinical differential diagnosis.

Orphanet J Rare Dis 2019 Feb 13;14(1):41. Epub 2019 Feb 13.

Genome Research Division, Human Genetics department, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525KL, Nijmegen, The Netherlands.

Background: Bartter Syndrome is a rare, genetically heterogeneous, mainly autosomal recessively inherited condition characterized by hypochloremic hypokalemic metabolic alkalosis. Mutations in several genes encoding for ion channels localizing to the renal tubules including SLC12A1, KCNJ1, BSND, CLCNKA, CLCNKB, MAGED2 and CASR have been identified as underlying molecular cause. No genetically defined cases have been described in the Iranian population to date. Read More

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http://dx.doi.org/10.1186/s13023-018-0981-5DOI Listing
February 2019

Revision of the Lymphedema Functioning, Disability and Health Questionnaire for Upper Limb Lymphedema (Lymph-ICF-UL): Reliability and Validity.

Lymphat Res Biol 2019 Feb 13. Epub 2019 Feb 13.

1 Department of Rehabilitation Sciences, KU Leuven-University of Leuven, Research Group for Rehabilitation in Internal Disorders, Leuven, Belgium.

Background: Lymphedema is associated with significant physical and psychosocial problems. The Lymphedema Functioning, Disability and Health questionnaire for upper limb lymphedema is a valid and reliable tool quantifying the amount of problems in functioning in patients with breast cancer-related lymphedema. Patients suggested a revision of the scoring system to facilitate completion of the questionnaire. Read More

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http://dx.doi.org/10.1089/lrb.2018.0025DOI Listing
February 2019

Systematic Symptom Reporting by Pediatric Palliative Care Patients with Cancer: A Preliminary Report.

J Palliat Med 2019 Feb 13. Epub 2019 Feb 13.

1 Department of Palliative, Rehabilitation and Integrative Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas.

Background: Systematic symptom assessment is not a standard of care in children with cancer. Many well-known symptom assessment tools are lengthy or difficult to integrate into a daily pediatric palliative care practice. We created a series of brief and simple questions to be systematically given to children and their caregivers. Read More

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http://dx.doi.org/10.1089/jpm.2018.0545DOI Listing
February 2019

Smartphone Application Versus Pedometer to Promote Physical Activity in Prostate Cancer Patients.

Telemed J E Health 2019 Feb 13. Epub 2019 Feb 13.

1 Department of Rehabilitation Medicine and Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Background: Recently, the application of smartphone in medical field has received great attention.

Introduction: The objective of this study was to compare the effectiveness of smartphone-based and conventional pedometer-based exercise monitoring systems in promoting home exercise among prostate cancer patients.

Methods: Prostate cancer patients who have undergone surgery or androgen deprivation therapy were recruited. Read More

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http://dx.doi.org/10.1089/tmj.2018.0233DOI Listing
February 2019

Patient's Decisional Control Preferences of a Cohort of Patients With Advanced Cancer Receiving Palliative Care in India.

J Palliat Care 2019 Feb 13:825859719827316. Epub 2019 Feb 13.

1 Department of Palliative Medicine, Tata Memorial Centre, Mumbai, Maharashtra, India.

Context:: Frequency of passive decisional control preferences (DCPs) has been variably reported but is generally higher among patients living in developing countries.

Objectives:: This prospective cross-sectional study aimed to determine the frequency of passive DCP among patients with advanced cancer in a tertiary cancer center in India and to identify its association with their sociodemographic and clinical characteristics.

Methods:: Patients with advanced cancer referred to palliative care (between March and August 2016) underwent assessment of DCP using validated tools including Control Preference Scale, Satisfaction with Decision Scale, and understanding of illness questionnaire. Read More

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http://dx.doi.org/10.1177/0825859719827316DOI Listing
February 2019

Exercise-based rehabilitation for cancer survivors with chemotherapy-induced peripheral neuropathy.

Support Care Cancer 2019 Feb 12. Epub 2019 Feb 12.

Prince of Wales Clinical School, University of New South Wales, Kensington, Australia.

Purpose: Chemotherapy-induced peripheral neuropathy (CIPN) affects up to 40% of cancer survivors and is associated with functional deficits and an increased falls incidence. There are presently no strongly recommended treatment strategies for CIPN. The aim of this study was to evaluate the impact of a multimodal exercise intervention on CIPN symptoms and related functional deficits, as well as neurophysiologic parameters. Read More

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http://dx.doi.org/10.1007/s00520-019-04680-wDOI Listing
February 2019

Swallowing and Voice Outcomes following Treatment of Hypopharyngeal Cancer: The Need for Supervised Rehabilitation.

Adv Otorhinolaryngol 2019 12;83:118-125. Epub 2019 Feb 12.

Department ENT Head and Neck Surgery, VU University Medical Center, Amsterdam, The Netherlands.

Advances in and intensification of treatment in hypopharyngeal cancer have led to an increase in organ preservation and in overall survival. Treatment intensification comes at the cost of more pronounced acute and long-term side effects causing functional impairments in voice and swallowing. Swallowing and voice problems have a significant impact on communication, eating and nutrition, social well-being and quality of life. Read More

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http://dx.doi.org/10.1159/000492355DOI Listing
February 2019
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Patients' experiences with a behaviour change intervention to enhance physical activity in primary care: A mixed methods study.

PLoS One 2019 12;14(2):e0212169. Epub 2019 Feb 12.

Education Center, UMC Utrecht Academy, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

Objective: To explore the experiences of patients at risk for cardiovascular disease in primary care with the Activate intervention in relation to their success in increasing their physical activity.

Methods: A convergent mixed methods study was conducted, parallel to a cluster-randomised controlled trial in primary care, using a questionnaire and semi-structured interviews. Questionnaires from 67 patients were analysed, and semi-structured interviews of 22 patients were thematically analysed. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212169PLOS
February 2019
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Development of the Multidimensional Readiness and Enablement Index for Health Technology (READHY) Tool to Measure Individuals' Health Technology Readiness: Initial Testing in a Cancer Rehabilitation Setting.

J Med Internet Res 2019 Feb 12;21(2):e10377. Epub 2019 Feb 12.

Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

Background: The increasing digitization of health care services with enhanced access to fast internet connections, along with wide use of smartphones, offers the opportunity to get health advice or treatment remotely. For service providers, it is important to consider how consumers can take full advantage of available services and how this can create an enabling environment. However, it is important to consider the digital context and the attributes of current and future users, such as their readiness (ie, knowledge, skills, and attitudes, including trust and motivation). Read More

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http://dx.doi.org/10.2196/10377DOI Listing
February 2019
1 Read

Defining Exposures in Professional Football: Professional American-Style Football Players as an Occupational Cohort.

Orthop J Sports Med 2019 Feb 1;7(2):2325967119829212. Epub 2019 Feb 1.

Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Studies of professional American football players have shown that football-related activities lead to acute injuries and may have long-term adverse health outcomes including osteoarthritis, neurocognitive impairment, and cardiovascular disease. However, the full complement of what constitutes professional football exposure has yet to be effectively articulated. Most likely, professional football exposure encompasses a multifaceted array of experiences including head impacts and joint stresses, long-term pain medication use, dietary restrictions, and strenuous training regimens. Read More

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http://dx.doi.org/10.1177/2325967119829212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360475PMC
February 2019
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THE EFFECTS OF POSTERIOR TIBIAL MOBILIZATION ON MENISCAL MOVEMENT: AN IN-SITU INVESTIGATION.

Int J Sports Phys Ther 2019 Feb;14(1):32-45

Center for Rehabilitation Research, Texas Tech University Health Sciences Center, Lubbock, TX, USA.

Background: Anterior knee pain during knee extension may be related to a meniscal movement restriction and increased meniscal load during function. One method of treatment involves the use of manual posterior mobilization of the tibia to specifically target the meniscotibial interface of the knee joint.

Purpose: The purpose of this study was to measure motion at a cadaveric medial meniscus anterior horn during a posterior tibial mobilization. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350666PMC
February 2019
5 Reads

Postoperative vacuum therapy following AMS™ LGX 700® inflatable penile prosthesis placement: penile dimension outcomes and overall satisfaction.

Int J Impot Res 2019 Feb 11. Epub 2019 Feb 11.

Department of Urology, Coral Gables Hospital, 3100 Douglas Rd, Coral Gables, FL, 33134, USA.

Penile shortening after inflatable penile prosthesis for erectile dysfunction is a common postoperative patient complaint and can reduce overall satisfaction with the procedure. In this prospective study we report our results regarding penile dimensions and patient satisfaction outcomes after 1 year of follow-up from AMS™LGX700® penile prosthesis implant with 6 months of vacuum erectile device therapy. Seventy-four selected patients with medically refractory erectile dysfunction underwent AMS™ LGX 700® IPP placement. Read More

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http://dx.doi.org/10.1038/s41443-019-0125-zDOI Listing
February 2019

The Prevalence of Asymptomatic Cervical and Lumbar Facet Arthropathy: A Computed Tomography Study.

Asian Spine J 2019 Feb 13. Epub 2019 Feb 13.

Department of Rehabilitation Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.

Study Design: Case control study.

Purpose: To determine the prevalence and degree of asymptomatic cervical and lumbar facet joint arthritis. We retrospectively reviewed 500 computed tomography (CT) scans of cervical facet joints obtained from 50 subjects. Read More

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http://asianspinejournal.org/journal/view.php?doi=10.31616/a
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http://dx.doi.org/10.31616/asj.2018.0235DOI Listing
February 2019
1 Read

Modeling the Effects of Multiple Myeloma on Kidney Function.

Sci Rep 2019 Feb 11;9(1):1726. Epub 2019 Feb 11.

University of Nebraska Medical Center, Division of Oncology & Hematology, Omaha, 68198, USA.

Multiple myeloma (MM), a plasma cell cancer, is associated with many health challenges, including damage to the kidney by tubulointerstitial fibrosis. We develop a mathematical model which captures the qualitative behavior of the cell and protein populations involved. Specifically, we model the interaction between cells in the proximal tubule of the kidney, free light chains, renal fibroblasts, and myeloma cells. Read More

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http://dx.doi.org/10.1038/s41598-018-38129-7DOI Listing
February 2019

Cognitive rehabilitation is advantageous in terms of fatigue and independence in pediatric cancer treatment: a randomized-controlled study.

Int J Rehabil Res 2019 Feb 6. Epub 2019 Feb 6.

Department of Pediatric Oncology, Faculty of Medicine Sciences, Hacettepe University, Ankara, Turkey.

This study aimed to investigate the effect of task-oriented inpatient cognitive rehabilitation on fatigue perception and independence in daily activities. Forty (22 males, 18 females) children with pediatric cancer were randomized to either study [n=22; 10.81 (1. Read More

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http://dx.doi.org/10.1097/MRR.0000000000000340DOI Listing
February 2019

Palliative Cancer Care in the Outpatient Setting: Which Model Works Best?

Authors:
David Hui

Curr Treat Options Oncol 2019 Feb 11;20(2):17. Epub 2019 Feb 11.

Department of Palliative Care, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Unit 1414 - 1515 Holcombe Blvd., Houston, TX, 77030, USA.

Opinion Statement: Multiple randomized controlled trials have underscored the importance of timely referral to palliative care for patients with advanced cancer. Outpatient palliative care can facilitate timely referral and is increasingly available in many cancer centers. The key question is which model of outpatient palliative care is optimal. Read More

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http://dx.doi.org/10.1007/s11864-019-0615-8DOI Listing
February 2019

Optimising Radiation Therapy Dose to the Swallowing Organs at Risk: An In Silico Study of feasibility for Patients with Oropharyngeal Tumours.

Dysphagia 2019 Feb 11. Epub 2019 Feb 11.

Radiation Oncology, Nelune Comprehensive Cancer Centre, POWH, Sydney, NSW, 2031, Australia.

Recent evidence suggests that reducing radiotherapy dose delivered to specific anatomical swallowing structures [Swallowing Organs at Risk (SWOARs)] may improve swallowing outcomes post-treatment for patients with head and neck cancer. However, for those patients with tumours of the oropharynx, which typically directly overlap the SWOARs, reducing dose to these structures may be unachievable without compromising on the treatment of the disease. To assess the feasibility of dose reduction in this cohort, standard IMRT plans (ST-IMRT) and plans with reduced dose to the SWOARs (SW-IMRT) were generated for 25 oropharyngeal cancer patients (Brouwer et al. Read More

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http://dx.doi.org/10.1007/s00455-019-09983-yDOI Listing
February 2019
1 Read

The association between having assistive devices and activities of daily living ability and health-related quality of life: An exploratory cross-sectional study among people with advanced cancer.

Eur J Cancer Care (Engl) 2019 Feb 10:e13002. Epub 2019 Feb 10.

Research Unit of General Practice, Department of Public Health, The Research Initiative for Activity Studies and Occupational Therapy, University of Southern Denmark, Odense C, Denmark.

Objective: To explore whether people with advanced cancer who had assistive devices had higher or lower ADL ability and/or HRQoL than people with advanced cancer who did not have assistive devices.

Methods: A cross-sectional study of 164 participants with advanced cancer. Self-reported ADL ability and HRQoL were assessed using the ADL-Interview and the EORTC QLQ-C30. Read More

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http://dx.doi.org/10.1111/ecc.13002DOI Listing
February 2019

Identification of Alzheimer's Disease-Related Genes Based on Data Integration Method.

Front Genet 2018 25;9:703. Epub 2019 Jan 25.

Department of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China.

Alzheimer disease (AD) is the fourth major cause of death in the elderly following cancer, heart disease and cerebrovascular disease. Finding candidate causal genes can help in the design of Gene targeted drugs and effectively reduce the risk of the disease. Complex diseases such as AD are usually caused by multiple genes. Read More

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http://dx.doi.org/10.3389/fgene.2018.00703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355707PMC
January 2019
1 Read

Group-based exercise interventions for increasing physical activity in cancer survivors: a systematic review of face-to-face randomized and non-randomized trials.

Support Care Cancer 2019 Feb 9. Epub 2019 Feb 9.

Department of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, VA, USA.

Purpose: To increase physical activity (PA), interventions based on group dynamics may be superior to interventions that target aggregates of people but do not have formal strategies to enhance cohesion. This review examined the extent to which group dynamics processes have been integrated within exercise and/or PA interventions in cancer survivors, and explored the implementation and effectiveness of these interventions for increasing PA.

Methods: A systematic review was conducted of English articles published January 2005-March 13, 2017 using the electronic databases PsycINFO, CINAHL, and PubMed Medline (National Library of Medicine). Read More

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http://dx.doi.org/10.1007/s00520-019-04670-yDOI Listing
February 2019

Randomized placebo-controlled double-blind phase II study of zaltoprofen for patients with diffuse-type and unresectable localized tenosynovial giant cell tumors: a study protocol.

BMC Musculoskelet Disord 2019 Feb 9;20(1):68. Epub 2019 Feb 9.

Department of Orthopaedic Surgery, Kanazawa University Graduate School of Medical Sciences, 13-1 Takara-machi, Kanazawa, 920-8641, Japan.

Background: A tenosynovial giant cell tumor (TGCT) is a locally aggressive benign neoplasm arising from intra- or extra-articular tissue. Diffuse TGCT (D-TGCT) most commonly develops in the knee, followed by the hip, ankle, elbow, and shoulder. Surgical removal is the only effective treatment option for the patients. Read More

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http://dx.doi.org/10.1186/s12891-019-2453-zDOI Listing
February 2019
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Easy Volumeter in Detection of Breast Cancer-Related Lymphedema: A Validity Study.

Lymphat Res Biol 2019 Feb 8. Epub 2019 Feb 8.

2 Department of Physical Medicine and Rehabilitation, Dokuz Eylul University Hospital, İzmir, Turkey.

Aim and Hypothesis: The standard volumeter is heavy and fragile, and using the same volumeter for different patients can result in hygiene problems. These disadvantages point to the need for the development of a new model of volumeter. The new volumeter put forward in this study is lighter, smaller, sturdier, and easier to clean, while also having its own scale. Read More

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http://dx.doi.org/10.1089/lrb.2018.0040DOI Listing
February 2019
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Alerting the illusion of smoking improves quality of life in Chinese male cancer survivors.

Cancer Med 2019 Feb 8. Epub 2019 Feb 8.

Institute of Clinical Epidemiology, Key Laboratory of Public Health Safety, Ministry of Education, Key Lab of Health Technology Assessment of Ministry of Health, School of Public Health, Fudan University, Shanghai, China.

Objective: To examine the association between smoking status and quality of life (QOL) among cancer survivors in China.

Methods: A cross-sectional study was performed in 2725 male cancer survivors who were members of Cancer Rehabilitation Club and completed the questionnaires in 2013. Using linear regression models adjusted for confounders, we measured the association between QOL and former smokers as well as current (occasional, <10 cigarettes/day, and ≥ 10 cigarettes/day) smokers compared with never smokers. Read More

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http://doi.wiley.com/10.1002/cam4.1999
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http://dx.doi.org/10.1002/cam4.1999DOI Listing
February 2019
3 Reads

Personalised and progressive neuromuscular electrical stimulation (NMES) in patients with cancer-a clinical case series.

Support Care Cancer 2019 Feb 8. Epub 2019 Feb 8.

School of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland.

Purpose: Neuromuscular electrical stimulation (NMES) may be a pragmatic short-term alternative to voluntary exercise to augment cancer rehabilitation. However, previous attempts to use NMES as an exercise modality in this cohort have been unsuccessful, largely due to the use of NMES protocols that were developed for other rehabilitation contexts. We assessed the effects of a personalised and progressive NMES exercise intervention, designed with early-stage cancer rehabilitation in mind, on exercise capacity, lower body functional strength and quality of life in (QoL) in patients who are currently undergoing or have recently completed treatment for cancer. Read More

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http://dx.doi.org/10.1007/s00520-019-04679-3DOI Listing
February 2019
1 Read

Bone grafting materials in dentoalveolar reconstruction: A comprehensive review.

Jpn Dent Sci Rev 2019 Nov 28;55(1):26-32. Epub 2018 Sep 28.

2nd Department of Propedeutic Surgery, Laiko General Hospital, Medical School, University of Athens, Athens, Greece.

Bone deficits of the jaws are often attributed to accidents, surgical removal of benign lesions or malignant neoplasms, congenital abnormalities, periodontal inflammation, tooth abscess or extraction and finally jaw atrophy due to advanced age or general disease. These bone defects require rehabilitation for a variety of reasons, e.g. Read More

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http://dx.doi.org/10.1016/j.jdsr.2018.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354279PMC
November 2019
1 Read

Functional and aesthetic treatment outcomes after immediate jaw reconstruction using a fibula flap and dental implants.

J Craniomaxillofac Surg 2019 Jan 3. Epub 2019 Jan 3.

University Hospital Giessen, Dept. for Maxillofacial Surgery, (Head: Prof. Dr. Hans-Peter Howaldt), Klinikstr. 33, 35392, Giessen, Germany.

Purpose: Microvascular fibula flap surgery is a reliable and effective procedure for reconstructing the jaws after tumour surgery. This procedure allows the placement of dental implants after bone consolidation. This study was designed to evaluate the oral, functional, and aesthetic rehabilitation of tumour patients with immediate fibula transfer and dental implants and included assessment of diet, speech, and aesthetics. Read More

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http://dx.doi.org/10.1016/j.jcms.2018.12.017DOI Listing
January 2019

Pregnancy outcomes in women with spinal cord injuries: a population-based study.

PM R 2019 Feb 6. Epub 2019 Feb 6.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Background: Pregnant women with congenital or acquired spinal cord injury face challenges due to compromised neurological function and mobility; factors that may also affect fetal/infant health. Few studies have examined pregnancy course and longer-term outcomes in this population.

Objective: To assess pregnancy outcomes among women with spinal cord injury, paralysis, or spina bifida using population-based data. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/pmrj.12122
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http://dx.doi.org/10.1002/pmrj.12122DOI Listing
February 2019
2 Reads

Team-Based Medicine: Incorporating a Clinical Pharmacist into Pain and Opioid Practice Management.

PM R 2019 Feb 6. Epub 2019 Feb 6.

Department of Pharmacy, Virginia Mason Medical Center, Seattle, WA, USA.

Background: The Center for Disease Control (CDC) reports death from opioids increased by more than five times since 1999. In response, federal and state organizations have released guidelines recommending best practice standards to combat the opioid epidemic.

Objective: To evaluate the impact of a clinical pharmacist in a team-based care model on the adherence to best practice standards and access to care for management of patients on chronic opioid therapy (COT). Read More

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http://dx.doi.org/10.1002/pmrj.12127DOI Listing
February 2019
1 Read

Physical Therapy Based Exercise Protocol for Cancer patients: Evaluating Outcomes for Cardiopulmonary Performance and Cancer-Related Fatigue.

PM R 2019 Feb 6. Epub 2019 Feb 6.

Director, Clinical Research: Courage Kenny Rehabilitation Institute, Allina Health, MN.

Background: Studies have shown that rehabilitation and fitness throughout cancer treatment interventions have been linked to improved outcomes for morbidity and mortality of cancer patients. This study serves to detail the efficacy of the Cancer Rehabilitation Physical Therapy Fitness and Debility (Ca PT) Program in cancer patients.

Objective: To describe the clinical population of cancer patients referred to the Ca PT Program and evaluate the efficacy of the program's therapy protocol in improving cardiopulmonary performance and cancer-related fatigue and pain. Read More

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http://dx.doi.org/10.1002/pmrj.12128DOI Listing
February 2019
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Mortality due to cardiovascular disease, respiratory disease, and cancer in adults with cerebral palsy.

Dev Med Child Neurol 2019 Feb 6. Epub 2019 Feb 6.

Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.

Aim: To compare mortality rates for cardiovascular disease, cancer, and respiratory disease between adults with cerebral palsy (CP) and the general population.

Method: A cohort study was conducted using data from adults with CP in England, identified through a primary care data set (the Clinical Practice Research Datalink), with linked data on death registrations from the Office for National Statistics. Cause of death was categorized according to International Classification of Diseases codes. Read More

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http://dx.doi.org/10.1111/dmcn.14176DOI Listing
February 2019
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Impact of Preoperative Skeletal Muscle Mass and Nutritional Status on Short-and Long-Term Outcomes After Esophagectomy for Esophageal Cancer: A Retrospective Observational Study : Impact of Psoas Muscle Mass and Body Mass on Esophagectomy.

Ann Surg Oncol 2019 Feb 6. Epub 2019 Feb 6.

Keiyukai Sapporo Hospital, Sapporo, Hokkaido, Japan.

Background: Preoperative muscle volume and body mass index (BMI) are associated with postoperative outcomes. Because esophagectomy for esophageal cancer (EC) is associated with high morbidity and because EC has a poor prognosis, this study investigated the association of preoperative skeletal muscle mass and nutritional status with postoperative outcomes.

Methods: The study analyzed 483 patients who underwent esophagectomy from 2009 to 2012. Read More

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http://dx.doi.org/10.1245/s10434-019-07188-zDOI Listing
February 2019
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Electroceutical Targeting of the Autonomic Nervous System.

Physiology (Bethesda) 2019 Mar;34(2):150-162

Department of Physical Medicine and Rehabilitation, University of Pittsburgh School of Medicine , Pittsburgh, Pennsylvania.

Autonomic nerves are attractive targets for medical therapies using electroceutical devices because of the potential for selective control and few side effects. These devices use novel materials, electrode configurations, stimulation patterns, and closed-loop control to treat heart failure, hypertension, gastrointestinal and bladder diseases, obesity/diabetes, and inflammatory disorders. Critical to progress is a mechanistic understanding of multi-level controls of target organs, disease adaptation, and impact of neuromodulation to restore organ function. Read More

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http://dx.doi.org/10.1152/physiol.00030.2018DOI Listing
March 2019
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Dysphagia optimized radiotherapy to reduce swallowing dysfunction severity in patients undergoing treatment for head and neck cancer: A systematized scoping review.

Head Neck 2019 Feb 5. Epub 2019 Feb 5.

Division of Speech Pathology, School of Health and Rehabilitation Sciences, The University of Queensland, St Lucia, Queensland, Australia.

This study involved a systematized scoping review to coalesce current evidence on dysphagia outcomes achieved through active sparing of the swallowing structures in patients receiving radiotherapy for head and neck cancer. Eligible publications between 2007 and 2017 were reviewed and synthesized regarding participant demographics, treatment regimens, swallowing structures chosen for optimization, dosimetric constraints, and dysphagia measures. Nine prospective cohort studies were included. Read More

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http://dx.doi.org/10.1002/hed.25688DOI Listing
February 2019
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Psychological resilience of women after breast cancer surgery: a cross-sectional study of associated influencing factors.

Psychol Health Med 2019 Feb 5:1-13. Epub 2019 Feb 5.

a Department of Preventive Medicine , Shantou University Medical College , Shantou , Guangdong , China.

The psychological resilience (PR) of postoperative patients is found relatively low in clinical work. We recruited 220 postoperative women with breast cancer to survey PR of them and the influencing factors. General demographic data and physical exercise status were collected by questionnaire, clinical characteristics data were obtained from medical records. Read More

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http://dx.doi.org/10.1080/13548506.2019.1574353DOI Listing
February 2019
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[Low Anterior Resection Syndrome - Diagnosis - Therapy - Prophylaxis].

Zentralbl Chir 2019 Feb 5. Epub 2019 Feb 5.

MVZ Portal 10, Münster, Deutschland.

Background: As 5-year survival after rectal cancer surgery has reached 80%, there is increasing interest in quality of life. Low anterior resection syndrome (LARS) is an overall measure of the postoperative functional disorder due to the surgical resection.

Material And Methods: A thorough review of the literature was undertaken to help to define LARS and develop an understanding of its pathophysiology, diagnosis, therapy, and prophylaxis. Read More

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http://dx.doi.org/10.1055/a-0754-2482DOI Listing
February 2019
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Wide Profiling of Circulating MicroRNAs in Spinocerebellar Ataxia Type 7.

Mol Neurobiol 2019 Feb 5. Epub 2019 Feb 5.

Laboratory of Genomic Medicine, Department of Genetics, National Rehabilitation Institute (INR-LGII), Calz. México-Xochimilco No. 289, Col. Arenal Guadalupe, 14389, Ciudad de México (CDMX), Mexico.

Spinocerebellar ataxia type 7 (SCA7), a neurodegenerative disease characterized by cerebellar ataxia and retinal degeneration, is caused by a CAG repeat expansion in the ATXN7 gene coding region. Disease onset and progression are highly variable between patients, thus identification of specific/sensitive biomarkers that can improve the monitoring of disease progression is an immediate need. Because altered expression of circulating microRNAs (miRNAs) has been shown in various neurological diseases, they could be useful biomarkers for SCA7. Read More

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http://dx.doi.org/10.1007/s12035-019-1480-yDOI Listing
February 2019

Palliative Care for Patients With Opioid Misuse.

JAMA 2019 02;321(5):511

Department of Palliative Care, Rehabilitation, and Integrative Medicine, University of Texas MD Anderson Cancer Center, Houston.

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http://dx.doi.org/10.1001/jama.2018.18640DOI Listing
February 2019
2 Reads

Extracellular vesicle-educated macrophages promote early Achilles tendon healing.

Stem Cells 2019 Feb 5. Epub 2019 Feb 5.

Department of Orthopedics and Rehabilitation, University of Wisconsin, Madison, Wisconsin.

Tendon healing follows a complex series of coordinated events that ultimately produces a mechanically inferior tissue more scar-like than native tendon. More regenerative healing occurs when anti-inflammatory M2 macrophages play a more dominant role. Mesenchymal stromal/stem cells (MSCs) are able to polarize macrophages to an M2 immunophenotype via paracrine mechanisms. Read More

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http://dx.doi.org/10.1002/stem.2988DOI Listing
February 2019
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Feasibility and Outcomes of an Exercise Intervention for Chemotherapy-Induced Heart Failure.

J Cardiopulm Rehabil Prev 2019 Jan 31. Epub 2019 Jan 31.

Department of Health Promotion & Behavioral Sciences, The University of Texas School of Public Health, Houston (Mr Tsai); Department of Behavioral Science (Mr Tsai, Ms Harrison, and Dr Basen-Engquist), Department of Cardiology, Division of Internal Medicine (Drs Mouhayar and Durand), Department of Biostatistics (Dr Song), Department of Nursing (Dr Fadol), and Clinical Research Support Center (Ms Massey), The University of Texas MD Anderson Cancer Center, Houston; and Cardiovascular Division, Washington University School of Medicine in St Louis, St Louis, Missouri (Dr Lenihan).

Purpose: Cancer treatment-related heart failure (HF) is an emerging health concern, as the number of survivors is increasing rapidly, and cardiac health issues are a leading cause of mortality in this population. While there is general evidence for the efficacy of exercise rehabilitation interventions, more research is needed on exercise rehabilitation interventions for patients specifically with treatment-induced HF and whether such interventions are safe and well-accepted. This study provides feasibility and health outcomes of a pilot exercise intervention for cancer survivors with chemotherapy-induced HF. Read More

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http://dx.doi.org/10.1097/HCR.0000000000000388DOI Listing
January 2019
2 Reads
1.679 Impact Factor