The targeted regulation of Gli1 by miR-361 to inhibit epithelia-mesenchymal transition and invasion of esophageal carcinoma cells.
Cancer Biomark 2017 Nov 3. Epub 2017 Nov 3.
Ocology Department, Chengde Medical College Affiliated Hospital, Chengde, Hebei, China.
Epithelia-mesenchymal transition (EMT) is critical for invasion and metastasis of esophageal carcinoma. Gli1, a transcriptional factor in Hedgehog pathway, is correlated with EMT, invasion and metastasis of tumors. However, its role in esophageal cancer is still unknown. Read More