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    2284 results match your criteria Canadian Urological Association Journal [Journal]

    1 OF 46

    Routine histopathological examination of the foreskin after circumcision for clinically suspected Lichen sclerosus in children: Is it a waste of resources?
    Can Urol Assoc J 2018 Feb 6. Epub 2018 Feb 6.
    Division of Urology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada.
    Introduction: Circumcision is one of the most widely performed procedures in the world. One of the indications for circumcision is Lichen sclerosis (LS). The natural history of LS in children is not as well-documented as in adult patients. Read More

    Evaluating the role for renal biopsy in T1 and T2 renal masses: A single-centre study.
    Can Urol Assoc J 2018 Feb 6. Epub 2018 Feb 6.
    Radiology and Diagnostic Imaging; University of Alberta, Edmonton, AB, Canada.
    Introduction: Once used primarily in the identification of renal metastasis and lymphomas, various urological bodies are now adopting an expanded role for the renal biopsy. We sought to evaluate the role of the renal biopsy in a Canadian context, focusing on associated adverse events, radiographic burden, and diagnostic accuracy.

    Methods: This retrospective review incorporated all patients undergoing ultrasound (US)/computed tomography (CT)-guided biopsies for T1 and T2 renal masses. Read More

    Developing improved tissue-engineered buccal mucosa grafts for urethral reconstruction.
    Can Urol Assoc J 2018 Feb 6. Epub 2018 Feb 6.
    University of Sheffield, Department of Materials Science & Engineering, Sheffield; United Kingdom.
    Introduction: We aimed to compare alternative synthetic scaffolds suitable for future implantation and to examine the use of an inhibitor of lysyl oxidase (beta-amino- propionitrile [β-APN]) to reduce contraction in these implants.

    Methods: Three synthetic scaffolds were compared to natural dermis as substrates for the production of tissue-engineered skin. For natural dermis, Euroskin was used to provide a cell-free cadaveric dermis. Read More

    Replacing surveillance cystoscopy with urinary biomarkers in followup of patients with non-muscle-invasive bladder cancer: Patients' and urologic oncologists' perspectives.
    Can Urol Assoc J 2018 Feb 6. Epub 2018 Feb 6.
    Introduction: Urinary biomarkers are being developed to detect bladder cancer recurrence/progression in patients with non-muscle invasive bladder cancer (NMIBC). We conducted a questionnaire-based study to determine what diagnostic accuracy and cost would such test(s) need for both patients and urologic oncologists to comfortably forgo surveillance cystoscopy in favor of these tests.

    Methods: Surveys were administered to NMIBC patients at followup cystoscopy visit and to physician members of the Society of Urologic Oncology. Read More

    Prostate cancer patients' experience and preferences for acquiring information early in their care.
    Can Urol Assoc J 2018 Feb 6. Epub 2018 Feb 6.
    Tom Baker Cancer Centre, Calgary, AB; Canada.
    Introduction: Prostate cancer patients' information needs are well-described, but little is known about their preferred sources and media for obtaining information. We sought to determine prostate cancer patients' experiences and preferences for acquiring information after diagnosis, a time of high information need.

    Method: Population surveys were conducted in four Canadian provinces in 2014-15. Read More

    Montreal electronic artificial urinary sphincters: Our futuristic alternatives to the AMS800™.
    Can Urol Assoc J 2017 Oct;11(10):E396-E404
    Jewish General Hospital, McGill University; Montreal, QC, Canada.
    Introduction: We aimed to present three novel remotely controlled hydromechanical artificial urinary sphincters (AUSs) and report their in-vitro and ex-vivo results.

    Methods: We successively developed three distinct hydromechanical AUSs on the basis of the existing AMS800device by incorporating an electronic pump. No changes were made to the cuff and balloon. Read More

    A novel approach to off-clamp partial nephrectomy demonstrates significant improvements in renal injury in an experimental porcine model.
    Can Urol Assoc J 2017 Oct;11(10):E390-E395
    Departments of Surgery, Division of Urology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
    Introduction: We sought to design a partial nephrectomy (PN) with contralateral total nephrectomy porcine model and assess the underlying mechanisms of ischemia reperfusion injury (IRI) after PN using a novel, clinically approved resection device.

    Methods: Domestic male pigs (n=9) underwent left lower pole PN, allocated to either standard (Group 1) or no ischemia PN (Group 2), followed by contralateral nephrectomy. Biochemical studies were performed at baseline, Day 2, and Day 7; after sacrifice, kidneys were processed for histological analysis. Read More

    Management of iatrogenic urorectal fistulae in men with pelvic cancer.
    Can Urol Assoc J 2017 Sep;11(9):E372-E378
    Department of Urology, University of Lisbon, School of Medicine, Hospital Santa Maria (CHLN), Lisbon; Portugal.
    Introduction: Urorectal fistula (URF) is a devastating complication of pelvic cancer treatments and a surgical challenge for the reconstructive surgeon. We report a series of male patients with URF resulting from pelvic cancer treatments, specifically prostate (PCa), bladder (BCa), and rectal cancer (RCa), and explore the differences and impact on outcomes between purely surgical and non-surgical treatment modalities.

    Methods: Between October 2008 and June 2015, 15 male patients, aged 59-78 years (mean 67), with URF induced by pelvic cancer treatments were identified in our institutions. Read More

    Chronic prostatitis/chronic pelvic pain syndrome is associated with previous colonoscopy.
    Can Urol Assoc J 2017 Sep;11(9):E367-E371
    Research Centre of Sleep Medicine, College of Medicine, Taipei Medical University, Taipei; Taiwan.
    Introduction: This study aimed to examine the association between chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and receipt of a prior colonoscopic examination using a population-based database.

    Methods: We used the Taiwan Longitudinal Health Insurance Database 2005 to retrieve the study sample. This study included 3933 patients with CP/CPPS and 3933 age-matched controls. Read More

    Widespread use of internet, applications, and social media in the professional life of urology residents.
    Can Urol Assoc J 2017 Sep;11(9):E355-E366
    Department of Urology, Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany.
    Introduction: Digital media have revolutionized communication and information dissemination in healthcare. We aimed to quantify and evaluate professional digital media use among urology residents.

    Methods: We designed a 17-item survey to assess usage and perceived usefulness of digital media, as well as communication type and device type and distributed it via email to 143 Canadian and 721 German urology residents. Read More

    Gentamicin bladder instillations decrease symptomatic urinary tract infections in neurogenic bladder patients on intermittent catheterization.
    Can Urol Assoc J 2017 Sep;11(9):E350-E354
    Department of Urology; University of Michigan, Ann Arbor, MI, United States.
    Introduction: This study aimed to determine if gentamicin bladder instillations reduce the rate of symptomatic urinary tract infection (UTI) in neurogenic bladder (NGB) patients on intermittent self-catheterization (ISC) who have recurrent UTIs. Secondary aims were to examine the effects of intravesical gentamicin on the organism resistance patterns.

    Methods: We retrospectively reviewed our prospective NGB database. Read More

    A contemporary population-based study of testicular sex cord stromal tumours: Presentation, treatment patterns, and predictors of outcome.
    Can Urol Assoc J 2017 Sep;11(9):E344-E349
    Department of Urology, University of California Davis, Sacramento, CA; United States.
    Introduction: We aimed to characterize demographic distribution, patient outcomes, and prognostic features of testicular sex cord stromal tumours (SCST) using a large statewide database.

    Methods: Adult male patients diagnosed with SCST between 1988 and 2010 were identified within the California Cancer Registry (CCR). Baseline demographic variables and disease characteristics were reported. Read More

    Can a supervised algorithmic assessment of men for prostate cancer improve the quality of care? A retrospective evaluation of a prostate assessment pathway in Saskatchewan.
    Can Urol Assoc J 2017 Sep;11(9):E338-E343
    Department of Community Health and Epidemiology; University of Saskatchewan, Saskatoon, SK, Canada.
    Introduction: The Saskatoon Prostate Assessment Pathway (SPAP) was developed in 2013 in part to decrease the wait times between physician referral and biopsy for patients with suspected prostate cancer. Using an algorithm carefully designed to optimize appropriate prostate biopsy rates, physicians can directly refer patients for biopsy through the SPAP without seeing a urologist. All other patients are referred to the Saskatoon Urology Associates (SUA). Read More

    Transrectal ultrasound-guided biopsy for prostate cancer detection: Systematic and/or magnetic-resonance imaging-targeted.
    Can Urol Assoc J 2017 Sep;11(9):E330-E337
    Department of Urology; Jewish General Hospital, McGill University, Montreal, QC, Canada.
    Introduction: Magnetic resonance imaging (MRI) is being more widely used in the detection of prostate cancer (PCa), particularly after an initial negative biopsy. In this study, we compared 12-core systematic biopsy (SYS), MRI-targeted biopsy (TAR), and the association of systematic and MRI-targeted (SYS+TAR) prostate biopsy in patients with previous biopsy and those who were biopsy-naive to evaluate the differences in terms of cancer detection and clinically significant cancer detection between the three modalities.

    Methods: Overall, 203 consecutive patients with suspicion of PCa were analyzed; 48. Read More

    Accuracy of kidney cancer diagnosis and histological subtype within Canadian cancer registry data.
    Can Urol Assoc J 2017 Sep;11(9):E326-E329
    Department of Urology, Dalhousie University, Halifax, NS; Canada.
    Introduction: Provincial/territorial cancer registries (PTCRs) are the mainstay for Canadian population-based cancer statistics. Each jurisdiction captures this data in a population-based registry, including the Nova Scotia Cancer Registry (NSCR). The goal of this study was to describe data from the NSCR regarding renal cell carcinoma (RCC) pathology subtype and method of diagnosis and compare it to the actual pathology reports to determine the accuracy of diagnosis and histological subtype assignment. Read More

    A population-based study of the use of radium 223 in metastatic castration-resistant prostate cancer: Factors associated with treatment completion.
    Can Urol Assoc J 2017 Oct;11(10):350-355
    Radiation Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada.
    Introduction: Radium 223 (Ra223) given for six cycles has proven efficacy in clinical trials, but its population-level generalizability has not been well-described. The objectives of this study were to describe population-based Ra223 use in the abiraterone and enzalutamide era and identify factors associated with completion.

    Methods: All Ra223 patients at the British Columbia Cancer Agency between September 2013 and February 2016 were identified. Read More

    Ipsilateral renal function preservation following minimally invasive partial nephrectomy: The effect of tumour characteristics and warm ischemic time.
    Can Urol Assoc J 2017 Oct;11(10):344-349
    Western University, Schulich School of Medicine and Dentistry and Department of Surgery, London Health Sciences Centre, Western University, London, ON, Canada.
    Introduction: The relative impact of preoperative and perioperative variables on renal function following partial nephrectomy (PN) is controversial. To further investigate, we assess the effects of tumour complexity, warm ischemic time (WIT), and volume of resected renal parenchyma on ipsilateral renal function (IRF) outcomes following minimally invasive PN.

    Methods: Of patients who underwent laparoscopic or robotic-assisted PN between 2002 and 2011 at our institution, 99 met our inclusion criteria. Read More

    Biopsychosocial impact of prostate cancer and androgen-deprivation therapy.
    Can Urol Assoc J 2017 Oct;11(10):338-343
    Department of Urology; Queen's University, Kingston, ON, Canada.
    Introduction: Prostate cancer is the most non-cutaneous malignancy in men, and androgen-deprivation therapy (ADT) is a cornerstone of management in advanced disease. The aim of this study was to evaluate the association of ADT with changes in depression and mental and physical quality of life (QoL) within a prospective patient cohort design.

    Methods: Patients were prospectively recruited and consented at a single academic health sciences centre in Ontario, Canada. Read More

    Feasibility of expert and crowd-sourced review of intraoperative video for quality improvement of intracorporeal urinary diversion during robotic radical cystectomy.
    Can Urol Assoc J 2017 Oct;11(10):331-336
    Division of Urology, Department of Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
    Introduction: Development of uretero-ileal stricture (UIS) after robotic-assisted radical cystectomy (RARC) may be dependent on surgical technique. Video review of intraoperative technique is an emerging paradigm for surgical quality improvement. We examined whether surgeon-perceived risk of UIS or crowd-sourced assessment of robotic skill are associated with the development of UIS. Read More

    Intraureteral lidocaine for ureteral stent symptoms post-ureteroscopy: A randomized, phase 2, placebo-controlled trial.
    Can Urol Assoc J 2017 Oct;11(10):326-330
    Department of Urology; Queen's University, Kingston, ON, Canada.
    Introduction: Ureteral stent and ureteral manipulation-related pain is a significant complication for patients undergoing ureteroscopy. Herein, we report a phase 2, randomized trial to assess efficacy of direct instillation of intraureteral lidocaine in reducing postoperative pain and ureteral stent symptoms.

    Methods: We performed a randomized, double-blinded trial of patients undergoing elective ureteroscopy for ureteral calculi. Read More

    Hilar control during laparoscopic donor nephrectomy: Practice patterns in Canada.
    Can Urol Assoc J 2017 Oct;11(10):321-324
    Division of Urology, Western University, London, ON, Canada.
    Introduction: In recent years, the method of vascular control during laparoscopic donor nephrectomy (LDN) has come under scrutiny due to catastrophic consequences of a device failure. This study sought to examine the surgical preferences of Canadian donor surgeons with regards to vascular control and their perception on the safety of these modalities. We also surveyed the experience with device malfunction and their subsequent management during LDN. Read More


    Prostate cancer screening among family physicians in Ontario: An update on attitudes and current practice.
    Can Urol Assoc J 2017 Dec 1. Epub 2017 Dec 1.
    McMaster Institute of Urology, McMaster University, Hamilton, ON, Canada.
    Introduction: This study serves as an update of prostate cancer screening practices among family physicians in Ontario, Canada. Since this population was first surveyed in 2010, the Canadian Task Force on Preventive Health Care (CTFPHC) and the United States Preventive Services Task Force (USPSTF) released recommendations against prostate cancer screening.

    Methods: An online survey was developed through input from urologists and family practitioners. Read More

    Functional and oncological outcomes of salvage external beam radiotherapy following robot-assisted radical prostatectomy in a Canadian cohort.
    Can Urol Assoc J 2017 Dec 1. Epub 2017 Dec 1.
    Section of Urology, Department of Surgery, Centre Hospitalier de l'Université de Montréal.
    Introduction: We sought to determine the impact of salvage radiotherapy (SRT) on oncological and functional outcomes of patients with prostate cancer after biochemical recurrence (BCR) following robot-assisted radical prostatectomy (RARP).

    Methods: Data of 70 patients with prostate cancer treated with SRT after developing BCR were retrospectively analyzed from a prospectively collected RARP database of 740 men. Oncological (PSA) and functional (pads/day, International Prostate Symptom Score [IPSS], and Sexual Health Inventory for Men [SHIM]) outcomes were reported at six, 12, and 24 months after RT and adjusted for pre-SRT status. Read More

    Long-term patient outcomes from the first year of a robotic surgery program using multi-surgeon implementation.
    Can Urol Assoc J 2017 Dec 1. Epub 2017 Dec 1.
    The Ottawa Hospital Research Institute.
    Introduction: There is concern that surgical quality initially declines during the learning phase of robotic surgery. At our institution, we used a multi-surgeon programmatic approach to the introduction of robotic surgery. The purpose of this study was to evaluate outcomes of patients treated during the first year of our program. Read More

    Next-generation prostate cancer risk calculator for primary care physicians.
    Can Urol Assoc J 2017 Dec 1. Epub 2017 Dec 1.
    Division of Urology and Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Division of Urology, Michael Garron Hospital and Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada; Division of Urology, Western University, London, ON, Canada; Department of Urology, Dalhousie University, Halifax, NS, Canada; Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, United States.
    Introduction: Current prostate cancer risk calculators are limited in impact because only a probability of having prostate cancer is provided. We developed the next generation of prostate cancer risk calculator that incorporates life expectancy in order to better evaluate prostate cancer risk in context to a patient's age and comorbidity.

    Methods: We combined two cohorts to develop the new risk calculator. Read More

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