6,625 results match your criteria Canadian Journal of Cardiology[Journal]


Colchicine Use and Incident Coronary Artery Disease in Male Patients with Gout.

Can J Cardiol 2020 May 23. Epub 2020 May 23.

Section of Rheumatology; Division of Rheumatology.

Background: Inflammation is associated with coronary artery disease (CAD) and myocardial infarction (MI). Patients with gout are at increased risk of MI, and colchicine is associated with a reduced risk of MI. The objective of this study was to determine whether colchicine prevents incident development of CAD in patients with gout. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.026DOI Listing

Left atrial appendage thrombosis in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation.

Can J Cardiol 2020 May 22. Epub 2020 May 22.

Herzzentrum Dresden, Technische Universität Dresden, Department of Internal Medicine and Cardiology, Dresden, Germany. Electronic address:

Background: Data about the impact of left atrial appendage thrombosis (LAAT) on early safety and mortality in patients undergoing transfemoral transcatheter aortic valve implantation (TF-TAVI) are scarce. We aimed to investigate the incidence and predictors of LAAT and the outcome associated with this condition in patients treated by TF-TAVI.

Methods: Retrospective data analysis derived from a prospective single-center registry comparing patients with and without LAAT regarding early safety at 30-days according to Valve Academic Research Consortium-2 (VARC-2) and 2-year mortality. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.025DOI Listing

Influence of Bleeding Risk on Outcomes of Radial and Femoral Access for Percutaneous Coronary Intervention: An Analysis From the GLOBAL LEADERS Trial.

Can J Cardiol 2020 Feb 21. Epub 2020 Feb 21.

Andrzej Frycz Modrzewski Krakow University, Krakow, Poland; American Heart of Poland, Chrzanow, Poland.

Background: Radial artery access has been shown to reduce mortality and bleeding events, especially in patients with acute coronary syndromes. Despite this, interventional cardiologists experienced in femoral artery access still prefer that route for percutaneous coronary intervention. Little is known regarding the merits of each vascular access in patients stratified by their risk of bleeding. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.01.029DOI Listing
February 2020

Decrease and Delay in Hospitalization for Acute Coronary Syndromes during the 2020 SARS-CoV-2 Pandemic.

Can J Cardiol 2020 May 21. Epub 2020 May 21.

Structural Interventional Cardiology, Azienda Ospedaliero - Universitaria Careggi, Firenze, Italy, EU.

The diffusion of SARS-CoV-2 forced the Italian population to restrictive measures that modified the patients' response to non-SARS-CoV-2 medical conditions. We evaluated all ACS-patients admitted in three high-volume hospitals during the first month of SARS-CoV-2 Italian-outbreak and compared them to ACS-patients admitted during the same period 1-year before. Hospitalization for ACS decreased from 162 patients in 2019 vs 2020:84 patients in 2020. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242185PMC

The Use of Decision Modelling to Inform Timely Policy Decisions on Cardiac Resource Capacity during the COVID-19 Pandemic.

Can J Cardiol 2020 May 21. Epub 2020 May 21.

Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada; ICES, Toronto, Canada; Division of Cardiology, Department of Medicine, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada. Electronic address:

In Ontario, on March 16, 2020, a directive was issued to all acute care hospitals to halt non-essential procedures in anticipation for a potential surge in COVID-19 patients. This included scheduled outpatient cardiac surgical and interventional procedures that required the use of intensive care units, ventilators, and skilled critical care personnel, given that these procedures would draw from the same pool of resources required for critically ill COVID-19 patients. We adapted the COVID-19 Resource Estimator (CORE) decision analytic model by adding a cardiac component to determine the impact of various policy decisions on the incremental waitlist growth and estimated waitlist mortality for three key groups of cardiovascular disease patients; coronary artery disease, valvular heart disease, and arrhythmias. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241392PMC

Identifying Guideline-Practice Gaps to Optimize Evaluation and Management for Patients with Syncope.

Can J Cardiol 2020 May 21. Epub 2020 May 21.

Syncope is a common and complex symptom that requires efficient evaluation to determine the etiology. Recent guidelines focus on high-value testing, but a systematic evaluation of their implementation has not been performed. To this end, we used a mixed methods approach of surveys, chart reviews and focus groups to understand current practices relating to the diagnosis and management of patients with syncope and to identify barriers and facilitators to the implementation of guideline-supported recommendations. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.022DOI Listing

Diagnostic CMR Imaging Criteria in Noncompaction Cardiomyopathy and the Yield of Genetic Testing.

Can J Cardiol 2020 May 20. Epub 2020 May 20.

Department of Cardiology and Nuclear Medicine at the Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands; Department of Radiology and Nuclear Medicine at the Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. Electronic address:

Background: Noncompaction cardiomyopathy (NCCM) is characterized by a thickened myocardial wall with excessive trabeculations of the left ventricle and around 30% is explained by a (likely) pathogenic variant ((L)PV) in a cardiomyopathy gene. Diagnosing a (L)PV is important because it allows to identify accurately which relatives are at risk and helps predicting prognosis. The goal of the study was to assess which specific clinical and morphological characteristics of the myocardium may predict a (L)PV and which of the Cardiovascular Magnetic Resonance Imaging (CMR) diagnostic criteria for NCCM can best be used for that purpose. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.021DOI Listing

Rare case of an adult with a stenotic acommissural unicuspid aortic valve.

Can J Cardiol 2020 May 19. Epub 2020 May 19.

First Department of Cardiology, Medical University of Gdansk, Gdansk, Poland.

The clinical image illustrates a very rare case of acommissural unicuspid aortic valve (UAV) detected in an adult with three-dimensional echocardiography. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.012DOI Listing

SYNCOPE IN PATIENTS WITH SEVERE AORTIC STENOSIS: More than only an obstructive issue.

Can J Cardiol 2020 May 18. Epub 2020 May 18.

Servei de Cardiologia. Hospital Universitari Vall d'Hebron. Vall d'Hebron Institut de Recerca. Universitat Autònoma de Barcelona. CIBER-ESP. Barcelona (Spain).

Background: Severe aortic stenosis (AoS) is considered a primary cause of syncope. However, other mechanisms may be present in these patients and accurate diagnosis can have important clinical implications. The aim of this study is to assess the different etiologies of syncope in patients with severe AoS and the impact of attaining a certain or highly probable diagnosis for the syncope on prognosis. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.04.047DOI Listing

Management and Treatment of COVID-19: The Chinese Experience.

Can J Cardiol 2020 Apr 17. Epub 2020 Apr 17.

Division of Pediatric Immunology and Allergy, Joe DiMaggio Children's Hospital, Hollywood, Florida, USA; Division of Rheumatology, Allergy, and Clinical Immunology, University of California, Davis, California, USA. Electronic address:

With more than 1,800,000 cases and 110,000 deaths globally, COVID-19 is one of worst infectious disease outbreaks in history. This paper provides a critical review of the available evidence regarding the lessons learned from the Chinese experience with COVID-19 prevention and management. The steps that have led to a near disappearance of new cases in China included rapid sequencing of the virus to establish testing kits, which allowed tracking of infected persons in and out of Wuhan. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162773PMC

Palliative care?! But this child's not dying: The burgeoning partnership between pediatric cardiology and palliative care.

Can J Cardiol 2020 May 10. Epub 2020 May 10.

Paediatric Advanced Care Team, Hospital for Sick Children, Toronto, Canada; Emily's House Children's Hospice, Toronto, Canada; Departments of Paediatrics and Family & Community Medicine, University of Toronto, Toronto, Canada. Electronic address:

The field of pediatric cardiology has witnessed major changes over the past few decades that have considerably altered patient outcomes, including decreasing mortality rates for many previously untreatable conditions. Despite this, some pediatric cardiology programs are increasingly choosing to partner with their institutional palliative care teams. Why is this? The field of palliative care has also experienced significant shifts over a similar period of time. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.04.041DOI Listing

Erdheim-Chester Disease: An Unusual Etiology of Recurrent Massive Pericardial Effusion.

Can J Cardiol 2020 May 8. Epub 2020 May 8.

Department of Cardiology. Electronic address:

Erdheim-Chester disease (ECD), a rare non-Langerhans cell histiocytosis, involves multiple systems and may display pericardial effusion. Herein, we report a 60-year-old man who presented with refractory pericardial effusion of "unknown" etiology. As in this patient, ECD should be considered when rapidly recurrent pericardial effusion is accompanied by a pseudotumoral lesion of the right atrium and other systemic manifestations. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.04.040DOI Listing

Do these genes make my heart look fat? Why molecular changes matter in congenital heart disease.

Can J Cardiol 2020 May 17. Epub 2020 May 17.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Laboratory Medicine Program, University Health Network, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.cjca.2020.05.020DOI Listing

Simplifying Physiological Left Bundle Branch Area Pacing Using a New Nine Partition Method.

Can J Cardiol 2020 May 16. Epub 2020 May 16.

Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China;. Electronic address:

Background: Left bundle branch area pacing (LBBaP) is accepted as a physiological form of pacing; however, it is complex and usually requires an expensive electrophysiological recording system.

Methods: A simplified approach ("nine partition method") was explored to perform LBBaP. In this method, right anterior oblique 30°fluoroscopic image of the ventricle was divided into nine sections ("3 x 3" partitions). Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.011DOI Listing

Cardiorespiratory Fitness is an Independent Predictor of Cardiovascular Morbidity and Mortality, and Improves Accuracy of Prediction Models.

Can J Cardiol 2020 May 16. Epub 2020 May 16.

Leviev Heart Center; Chaim Sheba Medical Center, affiliated to the Sackler School of Medicine, Tel-Aviv University. Electronic address:

Background: While cardiorespiratory fitness (CRF) is a strong independent predictor of adverse cardiovascular outcomes, it is not considered as a risk enhancer by current guidelines.

Methods: We evaluated asymptomatic self-referred adults aged 40-79 years free of cardiovascular disease at baseline who were screened annually and completed baseline exercise stress test. Baseline CRF was dichotomized into two groups: low (metabolic equivalents <8) and high. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.017DOI Listing

Cyclin dependent kinase inhibitor-2b controls fibrosis and functional changes in ischemia-induced heart failure via the BMI1-p15-Rb signaling pathway.

Can J Cardiol 2020 May 16. Epub 2020 May 16.

Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

Background: Cardiac fibrosis is an important cause of heart failure(HF) after myocardial infarction(MI). The cyclin dependent kinase inhibitor 2b(CDKN2b) regulates the cell cycle by encoding the p15 protein and participates in the development of various tumors. However, the role of CDKN2b/p15 in cardiac fibrosis and HF after MI remains unclear. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.016DOI Listing

Comparison of Heart Transplantation Outcomes - Adult Congenital Heart Disease Versus Matched Cardiac Patients in a Quaternary Reference Centre.

Can J Cardiol 2020 May 16. Epub 2020 May 16.

Department of Cardiovascular Surgery, Toronto General Hospital, Toronto, ON, Canada. Electronic address:

Background: The number of transplants performed for adult congenital heart disease (ACHD) patients is increasing. We sought to compare survival and post-transplant complications, including graft failure, rejection, dialysis and use of RVAD postoperatively, between ACHD and a cohort of dilated (DCM) and ischemic (ICM) cardiomyopathy patients matched in age and year of transplantation.

Methods: We retrospectively reviewed our single-institution heart transplant database and selected all patients who had surgery between 1988 and 2017. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.015DOI Listing

SNX10 deficiency restricts foam cell formation and protects against atherosclerosis by suppressing CD36-Lyn axis.

Can J Cardiol 2020 May 16. Epub 2020 May 16.

Institute of Fudan-Minhang Academic Health System, Minhang Hospital, Fudan University, Shanghai, China; Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai, China; National Institute of Allergy and Infectious, National Institute of Health, Rockville, USA. Electronic address:

Background: Atherosclerosis-related cardiovascular diseases are among the leading causes of mortality worldwide. Uptake of modified lipoproteins by monocyte-derived macrophages leads to the formation of foam cells, which by secreting pro-inflammatory cytokines accelerate plaque development. Sorting Nexin 10 (SNX10) plays a critical role in the regulation of macrophage functions as well as in the lipid metabolism. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.010DOI Listing
May 2020
3.711 Impact Factor

Unilateral Disease is Common in Patients with Primary Aldosteronism without Adrenal Nodules.

Can J Cardiol 2020 May 16. Epub 2020 May 16.

Department of Medicine, University of Calgary, Calgary, AB, Canada; Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada. Electronic address:

Background: Patients with primary aldosteronism without apparent adrenal nodularity have not been well characterised in the literature. The aim of this study was to characterise unilateral aldosterone hypersecretion among patients with PA with normal-appearing adrenals using AVS.

Methods: In this cross sectional study at a Canadian tertiary care centre, we reviewed all consecutive PA patients lacking a definitive adrenal nodule who were referred for AVS in the workup of PA between January 2006 and May 2018. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.013DOI Listing

Electrical Storm in a Patient With Rosai-Dorfman Disease With Intracardiac Masses and Myocardial Infiltration.

Can J Cardiol 2020 Mar 7. Epub 2020 Mar 7.

Coronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.

A 47-year-old woman with Rosai-Dorfman disease (RDD) presented with an electrical storm with sustained ventricular tachycardia. Echocardiography and computed tomography revealed an intracardiac mass involving the right atrium and left ventricle. Positron emission tomography demonstrated fluorodeoxyglucose avidity of the mass and myocardial infiltration; the electrical storm was attributed to this feature. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.03.004DOI Listing

Cardiovascular implications of the COVID-19 pandemic: a global perspective.

Can J Cardiol 2020 May 16. Epub 2020 May 16.

The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

The Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), represents the pandemic of the century, with approximately 3.5 million cases and 250,000 deaths worldwide as of May 2020. Although respiratory symptoms usually dominate the clinical presentation, COVID-19 is now known to also have potentially serious cardiovascular consequences, including myocardial injury, myocarditis, acute coronary syndromes, pulmonary embolism, stroke, arrhythmias, heart failure, and cardiogenic shock. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229739PMC

Avoiding Pajama Paralysis in the Cardiac Intensive Care Environment with Early Mobilization.

Can J Cardiol 2020 May 15. Epub 2020 May 15.

Department of Surgery, Max Rady College of Medicine, University of Manitoba, Canada; Institute of Cardiovascular Sciences, St. Boniface Hospital Research Centre, Winnipeg, Canada; Cardiac Sciences Program, St. Boniface Hospital, Winnipeg, Canada.

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http://dx.doi.org/10.1016/j.cjca.2020.05.014DOI Listing

Unusual midventricular LV obstruction with flow aimed to the apex due to apical RV pacing: elimination by sequential septo-apical RV pacing.

Can J Cardiol 2020 May 14. Epub 2020 May 14.

Clinic for Electrophysiology/Rhythmology.

We report the case of an 88-year-old male who developed a mid-left ventricular (LV) obstruction due to apical pacing to manage third-degree atrio-ventricular block. The flow generated by the obstruction was directed towards the LV apex and appeared from late systole to early diastole. The obstruction appeared to result from earlier contraction at the apex compared with the midventricular portion of the LV, which was followed by an also earlier apical relaxation. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.04.046DOI Listing

Isolated endomyocardial fibrosis of the right ventricle.

Can J Cardiol 2020 May 13. Epub 2020 May 13.

Service of Cardiology, Cardiovascular Department, Lausanne University Hospital (CHUV), Lausanne, Switzerland; University of Lausanne (UNIL), Lausanne, Switzerland.

We describe a case of tropical right ventricular (RV) endomyocardial fibrosis. By CMR, a typical pattern of RV dilatation with apical obliteration was found, and late gadolinium enhancement of the obliterated part was present, confirming fibrosis. By T1-mapping, myocardial extracellular volume was elevated suggesting associated intramyocardial interstitial fibrosis and highlighting the importance of tissue characterisation to diagnose this condition. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.04.045DOI Listing

Lung Ultrasound for Cardiologists in the Time of COVID-19.

Can J Cardiol 2020 May 13. Epub 2020 May 13.

Division of Respirology, University of Toronto, Toronto, Ontario, Canada; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada.

Lung ultrasound (LUS) is a point-of-care ultrasound (POCUS) technique used for its portability, widespread availability, and ability to provide real-time diagnostic information procedural guidance. LUS outperforms lung auscultation and chest X-ray, and is an alternative to chest computed tomography in select cases. Cardiologists may enhance their physical and echocardiographic examination with the addition of LUS. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235628PMC

A case of Behcet's disease myocarditis documented by cardiac magnetic resonance imaging.

Can J Cardiol 2020 May 13. Epub 2020 May 13.

- Radiology Department, Fattouma Bourguiba University Hospital and University of Monastir, Monastir, Tunisia.

Acute myocarditis is extremely rare in Behcet's disease (BD). Here we report a case of a 32-year-old man with a history of oral ulcerations who was admitted for fever and chest pain. On examination, he had bipolar ulcers with pseudofolliculitis and a positive pathergy test. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.006DOI Listing

Clinical Outcomes With Beta-Blocker Use in Patients With Recent History of Myocardial Infarction.

Can J Cardiol 2020 Feb 4. Epub 2020 Feb 4.

Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada; Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

Background: It is uncertain whether beta-blockers (BBs) are beneficial in contemporary stable patients with prior myocardial infarction (MI). Therefore, we sought to examine the effectiveness of BB use in this population.

Methods: We conducted a cohort study with the use of administrative databases of patients ≥ 65 years of age, alive on April 1, 2012 (index date) with a hospital discharge diagnosis of MI within the previous 3 years. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.01.024DOI Listing
February 2020

Invasive Hemodynamic Staging Classification of Cardiac Damage in Patients With Aortic Stenosis Undergoing Valve Replacement.

Can J Cardiol 2020 Feb 8. Epub 2020 Feb 8.

Cardiology Division, Kantonsspital, St Gallen, Switzerland.

Background: An echocardiographic 5-stage classification of cardiac damage in aortic stenosis (AS) has been shown to provide prognostic information. We aimed to create an analogous classification based on invasive hemodynamics.

Methods: We studied 421 patients (age 75 ± 10 years, 59% men) with severe AS with complete invasive hemodynamics obtained before aortic valve replacement (AVR). Read More

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http://dx.doi.org/10.1016/j.cjca.2020.02.004DOI Listing
February 2020

Ventricular Septal Defect Pulmonary Atresia: Provisional Bifurcation Strategy for Confluence Stenosis During Patent Ductus Arteriosis Stenting.

Can J Cardiol 2020 Mar 5. Epub 2020 Mar 5.

Department of Cardiology, Post Graduate Institute for Medical Education and Research (PGIMER), Chandigarh, India. Electronic address:

Neonates with pulmonary atresia survive only if duct patency is maintained before staged surgical repair. Ductal stenting is an effective alternative to conventional shunt surgery, as it avoids thoracotomy. With today's generation of coronary stents having better profile, flexibility, and trackability, it may be achieved safely, with less difficulty than previously described. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.02.094DOI Listing

Risk Factors for Mortality and Ventricular Tachycardia in Patients With Repaired Tetralogy of Fallot: A Systematic Review and Meta-analysis.

Can J Cardiol 2020 Feb 4. Epub 2020 Feb 4.

Heart Institute, Cincinnati Children`s Hospital Medical Center, Cincinnati, Ohio, USA; University of Cincinnati College of Medicine, Department of Pediatrics, Cincinnati, Ohio, USA. Electronic address:

Background: Patients with repaired tetralogy of Fallot (rTOF) have increased risk for mortality, sudden cardiac death, and ventricular tachycardia (VT). The aim of this systematic review and meta-analysis is to offer an updated analysis of risk factors following significant changes in surgical and perioperative management.

Methods: A meta-analysis based on the published literature between 2008 and 2018 was conducted. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.01.023DOI Listing
February 2020

Minimally Invasive Hybrid Approach to High Risk Mitral Disease With Severe Mitral Annular Calcification.

Can J Cardiol 2019 Dec 12. Epub 2019 Dec 12.

Division of Cardiac Surgery, Western University, London, Ontario, Canada. Electronic address:

Severe circumferential mitral annular calcification (MAC) remains a significant challenge, complicating surgical treatment of mitral valve disease. Transcatheter treatment options are attractive; however, they remain fraught with risks of annular fixation, paravalvular leak, atrioventricular-groove disruption, and left-ventricular outflow tract obstruction. We describe a novel minimally invasive hybrid technique of transcatheter mitral valve replacement in a patient with severe circumferential MAC. Read More

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http://dx.doi.org/10.1016/j.cjca.2019.12.008DOI Listing
December 2019

Interventional tricuspid valve repair after failed surgical tricuspid valve reconstruction.

Can J Cardiol 2020 May 12. Epub 2020 May 12.

Medizinische Klinik und Poliklinik I, Ludwig-Maximilians University Munich, Marchioninistraße 15, D-81377 Munich, Germany. Electronic address:

Tricuspid valve regurgitation is an independent predictor of increased mortality. Especially in elderly patients, tricuspid valve surgery is associated with high perioperative risks. Despite new therapeutic options with transcatheter valve repair, anatomical complexities especially resulting from pre-operated valves still remain everyday challenges. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.04.044DOI Listing

A Modern Integration of Palliative Care into the Management of Heart Failure.

Can J Cardiol 2020 May 12. Epub 2020 May 12.

Chief, Geriatrics and Palliative Medicine VA Portland Health Care System, and Professor of Medicine, Oregon Health & Sciences University, Portland OR 97239. Electronic address:

Heart failure (HF), a clinical syndrome with variable trajectory has become more common. As people with HF experience functional decline during periods of deterioration in their HF status, or with aging, their needs for palliative care increase. This review considers the palliative aspects of evidence-based HF care, which benefit patients while also addressing the underlying etiology of the HF. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.004DOI Listing

Hemodynamic collapse after influenza vaccination: a vaccine-induced fulminant myocarditis?

Can J Cardiol 2020 May 12. Epub 2020 May 12.

Department of Cardiovascular, Renal and Metabolic Medicine.

A 14-year-old girl with cardiopulmonary arrest was referred to our hospital. She had received an injection of inactivated influenza vaccine 7 days before the referral. Her cardiac rhythm was pulseless wide QRS tachycardia, and mechanical circulatory support was immediately commenced. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.005DOI Listing

Fit is It for Cardiovascular Disease Prediction, Prevention and Treatment.

Can J Cardiol 2020 May 12. Epub 2020 May 12.

Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland; Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.

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http://dx.doi.org/10.1016/j.cjca.2020.05.007DOI Listing

Blood Pressure at 6 Months after Acute Myocardial Infarction and Outcomes at 2 Years: The Perils Associated With Excessively Low Blood Pressures.

Can J Cardiol 2020 Feb 8. Epub 2020 Feb 8.

Division of Cardiology, Department of Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Background: This study aimed to determine the association between achieved blood pressure at 6-month follow-up and cardiovascular outcomes at 2 years in patients treated with β-blockers and renin-angiotensin-aldosterone blockers after acute myocardial infarction (AMI).

Methods: We analyzed data from 5503 patients enrolled in the national AMI registry. Patients with myocardial reinfarction (MrI), rehospitalization for heart failure (rHHF), or stroke before 6-month follow-up were excluded. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.01.026DOI Listing
February 2020

Resection of a Giant Bronchogenic Cyst in the Left Atrium.

Can J Cardiol 2020 Feb 24. Epub 2020 Feb 24.

Department of Cardiac Surgery, The People's Hospital of Guizhou Province, Guiyang, P.R. China. Electronic address:

A bronchogenic cyst in the left atrium is rare. We report the case of a 17-year-old male patient who was admitted to the emergency department because of severe chest pain and dyspnea. He was diagnosed using echocardiography and computed tomography, which revealed a huge cardiac tumour in the dome of the left atrium. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.02.078DOI Listing
February 2020

Successful Coronary Angiography Following Rapid Intravenous Desensitization for Refractory Contrast Allergy.

Can J Cardiol 2020 Mar 5. Epub 2020 Mar 5.

Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Division of Clinical Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada.

Most allergic reactions to radiocontrast media can be managed with a pretreatment protocol of steroids and antihistamines. However, in rare circumstances, patients can have severe allergic symptoms despite pretreatment. In this case, we highlight the use of a novel desensitization protocol in a patient with a severe breakthrough contrast allergy and unstable angina that allowed for successful percutaneous coronary intervention. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.02.097DOI Listing

Late-onset Fabry disease presenting with ventricular tachycardia originating from typical inferolateral scar.

Can J Cardiol 2020 May 11. Epub 2020 May 11.

Department of Cardiac Imaging, North West Heart Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK.

Late-onset cardiac Fabry disease is not uncommon among patients with unexplained left ventricular hypertrophy. Despite a less severe phenotype, life-threatening complications are possible in late-onset cardiac Fabry and may be the first presentation of the disease. Classical imaging features support the diagnosis, however, the presence of less common findings such as ischemic features should not lead to overlooking the diagnosis. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.04.042DOI Listing

Kawasaki Disease: Complex long term issues for Paediatric and Adult Cardiologists.

Authors:
Warwick Butt

Can J Cardiol 2020 May 11. Epub 2020 May 11.

Director Royal Childrens Hospital, Melbourne; Associate Professor, Department of Paediatrics University of Melbourne; Professor, Central Medical School, Department of Medicine Monash University; Group Leader, Clinical Sciences Theme, Murdoch Childrens Research Institute. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2020.04.043DOI Listing

Percutaneous Treatment of a Four-Leaf Clover Valve Using the MitraClip Technology.

Can J Cardiol 2019 Dec 16. Epub 2019 Dec 16.

Cardiovascular Department, GVM Care and Research, Maria Cecilia Hospital, Cotignola, Ravenna, Italy.

Percutaneous treatment of tricuspid valve regurgitation using MitraClip can be performed safely achieving improvement in reduction of regurgitation. Tricuspid valve shows different anatomic variations, in particular regarding the number of leaflets, which could represent a challenge for transcatheter valve intervention. We present a case of massive tricuspid regurgitation in a 4-leaf clover valve. Read More

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http://dx.doi.org/10.1016/j.cjca.2019.12.006DOI Listing
December 2019

Impact of Flow Dynamics on Device-Related Thrombosis After Left Atrial Appendage Occlusion.

Can J Cardiol 2020 May 11. Epub 2020 May 11.

Department of Cardiology, Hospital Clinic de Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2019.12.036DOI Listing

Coronary Drug-Eluting Stent Infection Complicated by Coronary Artery Aneurysm and Purulent Pericarditis: Complete Resolution Without Surgery.

Can J Cardiol 2020 Jan 20. Epub 2020 Jan 20.

Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Coronary stent infection is considered to be a rare but catastrophic complication of percutaneous coronary intervention. In this report, we present a 72-year-old man who developed a coronary stent infection complicated by coronary aneurysm and purulent pericarditis. Coronary artery aneurysm resolved over a period of 8 months following the successful management of infection with intensive antibiotic therapy alone. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.01.007DOI Listing
January 2020

Optimizing Access to Heart Failure Care in Canada during the COVID-19 Pandemic.

Can J Cardiol 2020 May 13. Epub 2020 May 13.

University of Manitoba, Winnipeg, Canada.

The traditional model of heart failure (HF) care in Canada, which relies upon a multi-disciplinary team and clinic based care processes, has been undermined as a result of the COVID-19 pandemic. As the pandemic continues, we will be challenged to improve or maintain the health status of those with HF by optimizing guideline-directed care despite physical distancing constraints and a reduction in the healthcare workforce. This will require development of new strategies specifically targeted at decreasing the risk of decompensation and resultant HF hospitalization. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217768PMC

Large Left-Atrial Appendage Occlusion With 2 Simultaneous LAmbre Devices: The More, the Better?

Can J Cardiol 2020 Jan 31. Epub 2020 Jan 31.

Cardiology Department, Hospital Universitario de Salamanca. Instituto de Investigación Biomédica de Salamanca (IBSAL), Spain.

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http://dx.doi.org/10.1016/j.cjca.2020.01.021DOI Listing
January 2020

Unintended Consequences: Perils of Renal Revascularization for Severe Hypertension.

Can J Cardiol 2020 Feb 4. Epub 2020 Feb 4.

Division of Nephrology, Department of Medicine, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada. Electronic address:

Revascularization of atherosclerotic renal artery stenosis may cure hypertension, but paradoxically, improvement in systemic blood pressure in response to successful revascularization may precipitate ischemia in other organs affected by previously silent atherosclerotic disease. We describe bowel ischemia secondary to preexisting celiac artery stenosis after revascularisation. Prior knowledge of multivessel disease facilitated prompt diagnosis and management of this condition. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.01.022DOI Listing
February 2020

Cardiac Malignant Peripheral Nerve Sheath Tumor Accessed By F-FDG PET/CT.

Can J Cardiol 2020 Jan 24. Epub 2020 Jan 24.

Hospital Metropolitano, Serra, Espírito Santo, Brazil.

This is a case report of a patient presenting an extremely rare cardiac malignancy: malignant peripheral nerve sheath tumour. The F-fluorodeoxyglucosis positron emission tomography associated to computed tomography (F-FDG PET/CT) accesses the tumour anatomy and metabolic activity, thereby making it possible to characterize a malignant neoplasm noninvasively. The diagnostic approach with F-FDG PET/CT spared the heart from a likely futile invasive procedure when detecting a distant metastasis and changed the biopsy site and therapeutic planning. Read More

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http://dx.doi.org/10.1016/j.cjca.2019.12.035DOI Listing
January 2020

Erratum.

Authors:

Can J Cardiol 2020 May 7. Epub 2020 May 7.

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http://dx.doi.org/10.1016/j.cjca.2020.05.002DOI Listing