127,577 results match your criteria Canadian Journal Of Agricultural Economics-revue Canadienne D Agroeconomie[Journal]


Delta opioid receptor activation modulates affective pain and modality-specific pain hypersensitivity associated with chronic neuropathic pain.

J Neurosci Res 2020 Jul 5. Epub 2020 Jul 5.

Department of Psychology and Centre for Neuroscience Studies, Queen's University, Kingston, ON, Canada.

Delta opioid receptor (DOR) agonists alleviate nociceptive behaviors in various chronic pain models, including neuropathic pain, while having minimal effect on sensory thresholds in the absence of injury. The mechanisms underlying nerve injury-induced enhancement of DOR function are unclear. We used a peripheral nerve injury (PNI) model of neuropathic pain to assess changes in the function and localization of DORs in mice and rats. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jnr.24680DOI Listing

Next-Generation Sequencing of CYP2C19 in Stent Thrombosis: Implications for Clopidogrel Pharmacogenomics.

Cardiovasc Drugs Ther 2020 Jul 4. Epub 2020 Jul 4.

Department of Cardiovascular Medicine, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.

Purpose: Describe CYP2C19 sequencing results in the largest series of clopidogrel-treated cases with stent thrombosis (ST), the closest clinical phenotype to clopidogrel resistance. Evaluate the impact of CYP2C19 genetic variation detected by next-generation sequencing (NGS) with comprehensive annotation and functional studies.

Methods: Seventy ST cases on clopidogrel identified from the PLATO trial (n = 58) and Mayo Clinic biorepository (n = 12) were matched 1:1 with controls for age, race, sex, diabetes mellitus, presentation, and stent type. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10557-020-06988-wDOI Listing

The role of school characteristics in pre-legalization cannabis use change among Canadian youth: implications for policy and harm reduction.

Health Educ Res 2020 Jul 5. Epub 2020 Jul 5.

School of Public Health and Health Systems, University of Waterloo, 200 University Avenue, Waterloo, ON N2L 3G1, Canada.

Reducing youth cannabis use in Canada is a public health priority with schools of interest as a potential modifier of behavior and as a venue for prevention programming. This work aimed to provide a basis for future policy and programming by evaluating pre-legalization cannabis use change patterns in schools and the impact of school characteristics on these patterns. Average rates of cannabis use behavior change (initiation, escalation, reduction, cessation) were collected from 88 high schools located in Ontario and Alberta, Canada participating in the COMPASS prospective cohort study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/her/cyaa018DOI Listing

Prevalence of abdominal obesity and associated lifestyle factors in bus drivers in a city in Southern Brazil.

Work 2020 Jun 27. Epub 2020 Jun 27.

Universidade Federal de Santa Catarina, Núcleo de Pesquisa em Cineantropometria e Desempenho Humano, Florianópolis, Santa Catarina, Brasil.

Background: Bus drivers are exposed to unique working conditions. However, the behavioral and health trends of these workers should be investigated.

Objective: To estimate the prevalence of abdominal obesity and associated lifestyle factors in bus drivers in a city in southern Brazil. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/WOR-203200DOI Listing

Effects of Probiotic Supplementation on Short Chain Fatty Acids in the AppNL-G-F Mouse Model of Alzheimer's Disease.

J Alzheimers Dis 2020 Jun 29. Epub 2020 Jun 29.

Department of Biomedical Sciences, University of North Dakota, School of Medicine and Health Sciences, Grand Forks, ND, USA.

Background: The intestinal microbiota and its metabolites, particularly short-chain fatty acids (SCFAs), have been implicated in immune function, host metabolism, and even behavior.

Objective: This study was performed to investigate whether probiotic administration influences levels of intestinal microbiota and their metabolites in a fashion that may attenuate brain changes in a mouse model of Alzheimer's disease (AD).

Methods: C57BL/6 wild-type (WT) mice were compared to AppNL-G-Fmice. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-200436DOI Listing

Recent Trends in Hospitalizations for Cardiovascular Disease, Stroke, and Vascular Cognitive Impairment in Canada.

Can J Cardiol 2020 Jun 18. Epub 2020 Jun 18.

Heart and Stroke Foundation of Canada, Toronto, Ontario, Canada. Electronic address:

Background: We analyzed hospitalization rates for a broad set of cardiovascular diseases, stroke, and vascular cognitive impairment (VCI) between 2007 and 2016 in Canada to characterize population-level trends and demographic and provincial/territorial variation in inpatient health care utilization.

Methods: Record-level administrative hospitalization data from April 1, 2007 to March 31, 2017 for individuals aged 0-105 years were obtained from the Canadian Institute for Health Information Discharge Abstract Database. Data were available for all provinces and territories, except Quebec. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cjca.2020.03.007DOI Listing

From Complexity to Consciousness.

Trends Neurosci 2020 Jun 24. Epub 2020 Jun 24.

Canadian Institute for Advanced Research, Azrieli Program in Brain, Mind, and Consciousness, Toronto, Canada; Department of Biomedical Clinical Sciences, University of Milan, Milan, Italy; IRCCS, Fondazione Don Gnocchi, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tins.2020.05.008DOI Listing

The impact of emergency department triage on the treatment outcomes of cancer patients with febrile neutropenia: A retrospective review.

Int Emerg Nurs 2020 Jul 1;51:100888. Epub 2020 Jul 1.

MUN School of Medicine, St. John's, Canada. Electronic address:

Introduction: The emergency department (ED) is an important entry point for patients with cancer requiring acute care due to oncological emergencies. Febrile neutropenia (FN) is one of the most common oncological emergencies and carries a significant risk of morbidity and mortality. There is evidence from previous studies that FN patients wait far longer in the ED than recommended by international guidelines. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ienj.2020.100888DOI Listing

Association Between HbA Levels and Cardiovascular Outcomes in Patients With Type 2 Diabetes and Cardiovascular Disease: A Secondary Analysis of the TECOS Randomized Clinical Trial.

Eur J Heart Fail 2020 Jul 4. Epub 2020 Jul 4.

Diabetes Trials Unit, University of Oxford, Oxford, UK.

Aims: Whether glycemic control is associated with cardiovascular outcomes in patients with type 2 diabetes (T2D) is unclear. Consequently, we assessed the relationship between glycated hemoglobin (HbA ) and cardiovascular outcomes in a placebo-controlled randomized trial which demonstrated no cardiovascular effect of sitagliptin in patients with T2D and atherosclerotic vascular disease.

Methods And Results: Secondary analysis of 14,656 TECOS participants with time to event analyses using multivariable Cox proportional hazard models. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ejhf.1958DOI Listing

Diagnostic accuracy of cognitive screening tools under different neuropsychological definitions for poststroke cognitive impairment.

Brain Behav 2020 Jul 3:e01671. Epub 2020 Jul 3.

Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.

Objectives: The accuracy of cognitive screening tools to detect poststroke cognitive impairment (PSCI) was investigated using various neuropsychological definitions.

Methods: Hospital-based stroke patients underwent a comprehensive neuropsychological assessment. The rate of PSCI was estimated using thresholds of 1, 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/brb3.1671DOI Listing

Assessing New Zealand's Cannabis Legalization and Control Bill: prospects and challenges.

Addiction 2020 Jul 4. Epub 2020 Jul 4.

SHORE & Whariki Research Centre, Massey University, P.O. Box 6137, Victoria Street West, Auckland, 1142, New Zealand.

Background: Few countries have developed detailed legislative proposals for legalizing cannabis. New Zealand recently released the Cannabis Legalization and Control Bill (CLCB) that will be the subject of a referendum in September 2020.

Aims: To assess the CLCB, drawing on emerging evidence from cannabis legalization overseas, public health research on alcohol and tobacco and the attempt to establish a regulated market for 'legal highs' in New Zealand. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/add.15144DOI Listing

Review article: prognostic significance of body composition abnormalities in patients with cirrhosis.

Aliment Pharmacol Ther 2020 Jul 3. Epub 2020 Jul 3.

Division of Gastroenterology & Liver Unit, University of Alberta Hospital, Edmonton, AB, Canada.

Background: Recent advances in evaluation of body composition show body mass index to be inadequate in differentiating between body compartments in cirrhosis. Given the limitations of body mass index, body composition evaluation using computed tomography has been increasingly used as a non-invasive clinical tool with prognostic value. Another factor influencing prognosis includes sex-specific differences in body composition that are seen in cirrhosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/apt.15927DOI Listing

Conscious perception and the modulatory role of dopamine: no effect of the dopamine D2 agonist cabergoline on visual masking, the attentional blink, and probabilistic discrimination.

Psychopharmacology (Berl) 2020 Jul 3. Epub 2020 Jul 3.

Department of Experimental and Applied Psychology, Institute for Brain and Behavior Amsterdam (iBBA) Vrije Universiteit, Amsterdam, Netherlands.

Rationale: Conscious perception is thought to depend on global amplification of sensory input. In recent years, striatal dopamine has been proposed to be involved in gating information and conscious access, due to its modulatory influence on thalamocortical connectivity.

Objectives: Since much of the evidence that implicates striatal dopamine is correlational, we conducted a double-blind crossover pharmacological study in which we administered cabergoline-a dopamine D2 agonist-and placebo to 30 healthy participants. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00213-020-05579-9DOI Listing

Clinical Learning, Didactic Education, and Research Experiences of Radiation Oncology Resident Physicians in Canada.

J Cancer Educ 2020 Jul 4. Epub 2020 Jul 4.

Division of Radiation Oncology, University of Alberta, Edmonton, AB, Canada.

Changes in the field of radiation oncology (RO) impacts residency training. Assessing trainee experiences is essential to inform curriculum development. We aim to explore gaps and strengths in current Canadian RO training, as we move towards competency-based medical education (CBME). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13187-020-01799-xDOI Listing

π covalency in the halogen bond.

Nat Commun 2020 Jul 3;11(1):3310. Epub 2020 Jul 3.

Department of Chemistry, The University of British Columbia, 2036 Main Mall, Vancouver, BC, V6T 1Z1, Canada.

Halogen bonds are a highly directional class of intermolecular interactions widely employed in chemistry and chemical biology. This linear interaction is commonly viewed to be analogous to the hydrogen bond because hydrogen bonding models also intuitively describe the σ-symmetric component of halogen bonding. The possibility of π-covalency in a halogen bond is not contemplated in any known models. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-020-17122-7DOI Listing

Comparison of two methods to clear the airways of critically ill children and adults with COVID-19 infection: a structured summary of a study protocol for a pilot randomized controlled trial.

Trials 2020 Jul 3;21(1):610. Epub 2020 Jul 3.

Department of Pediatrics, University of Montreal, CHU Sainte-Justine, 3175 Chemin de Côte Sainte Catherine, Quebec, QB, H3T 1C5, Canada.

Objectives: As there is no treatment for COVID-19 with a proven mortality benefit at this moment in the pandemic, supportive management including mechanical ventilation is the core management in an intensive care unit (ICU). It is a challenge to provide consistent care in this situation, highly demanding and leading to potential staff shortages in ICU. We need to reduce unnecessary exposure of healthcare workers to the virus. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13063-020-04533-6DOI Listing

Swinging the pendulum: lessons learned from public discourse concerning hydroxychloroquine and COVID-19.

Expert Rev Clin Immunol 2020 Jul 3. Epub 2020 Jul 3.

Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School , Boston, MA, USA.

Introduction: Several months into the COVID-19 pandemic, safe and effective treatments against this global health disaster have yet to be identified. Clinical research trials around the world are underway testing a wide array of possible medications. In particular, the off-label use of hydroxychloroquine for COVID-19 prophylaxis and treatment has created many unprecedented challenges for the scientific community and the public. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/1744666X.2020.1792778DOI Listing

Substance use disorders among youth with chronic physical illness.

Addict Behav 2020 Jun 23;110:106517. Epub 2020 Jun 23.

School of Public Health & Health Systems, University of Waterloo, Waterloo, Canada. Electronic address:

This study estimated prevalence of substance use disorder in youth with chronic physical illness; quantified magnitudes of association between different chronic physical illnesses with substance use disorder; and, tested whether mental disorder moderates these associations. Data come from 6,377 individuals aged 15-30 years in the Canadian Community Health Survey-Mental Health. Alcohol, cannabis, or other drug use disorder measured using the WHO Composite International Diagnostic Interview 3. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.addbeh.2020.106517DOI Listing

Allogenic Fecal Microbiota Transplantation in Patients With Nonalcoholic Fatty Liver Disease Improves Abnormal Small Intestinal Permeability: A Randomized Control Trial.

Am J Gastroenterol 2020 Jul;115(7):1055-1065

Department of Microbiology and Immunology, Western University, London, Ontario, Canada.

Introduction: Nonalcoholic fatty liver disease (NAFLD) is an obesity-related disorder that is rapidly increasing in incidence and is considered the hepatic manifestation of the metabolic syndrome. The gut microbiome plays a role in metabolism and maintaining gut barrier integrity. Studies have found differences in the microbiota between NAFLD and healthy patients and increased intestinal permeability in patients with NAFLD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14309/ajg.0000000000000661DOI Listing

Exploring the Contributions of Combined Model Regional Medical Education Campuses to the Physician Workforce.

Acad Med 2020 Jun 30. Epub 2020 Jun 30.

J. Bates was professor emerita, Department of Family Practice, University of British Columbia, Vancouver, British Columbia, Canada, at the time this work was done. ORCID: http://orcid.org/0000-0001-6940-2946. P. Grand'Maison is professor, Departments of Family Medicine and Emergency Medicine, Université de Sherbrooke, Sherbrooke, Quebec, Canada. S.R. Banner was CEO, Canadian Resident Matching Service, from 1986-2016, and is Director of Admissions for Canada, St. George's Medical School, Ottawa, Ontario, Canada. C.Y. Lovato is professor, School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada. K.W. Eva is professor and director of education research and scholarship, Department of Medicine, and associate director and senior scientist, Centre for Health Education Scholarship, University of British Columbia, Vancouver, British Columbia, Canada. ORCID: http://orcid.org/0000-0002-8672-2500.

Purpose: Physician shortages and maldistribution, particularly within family medicine, have led many medical schools worldwide to create regional medical campuses (RMCs) for clerkship training. However, Canadian medical schools have developed a number of RMCs in which all years of training (i.e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/ACM.0000000000003560DOI Listing

CAEP Joint Position Statement - Management of devastating brain injuries in the emergency department: Enhancing neuroprognostication and maintaining the opportunity for organ and tissue donation.

CJEM 2020 Jun 19:1-3. Epub 2020 Jun 19.

Division of Critical Care, Montreal Children's Hospital, McGill University Health Centre, Montreal, QC.

The primary purpose of this statement is to improve neuroprognostication after devastating brain injury (DBI), with a secondary benefit of potential organ and tissue donation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/cem.2020.357DOI Listing

The Canadian Occupational Performance Measure (COPM): a valuable tool for children with cerebral paresis.

Dev Med Child Neurol 2020 Jul 3. Epub 2020 Jul 3.

Occupational Therapy Department, Institute of Therapist and Midwifery, The Faculty of Health Sciences, Copenhagen University College, Copenhagen, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/dmcn.14617DOI Listing

Computer-guided implant surgery: analysis of dynamic navigation systems and digital accuracy.

J Biol Regul Homeost Agents 2020 May-Jun;34(3 Suppl. 1):9-17

Dept. of social dentistry and gnathological rehabilitation, National Institute for Health, Migration and Poverty (NIHMP), Roma, Italy.

After the static computer-guided implant surgery, borns the concept of "navigated implantology" (NI) that offers significant advantages in the treatment planning and help clinicians to perform successful implant rehabilitation. NI allows an optimal final location, to avoid the risk of damaging the noble anatomical structures near the site and allows the achievement of satisfactory aesthetics. The aim of this study is analyze three different systems: the RoboDent® system (Berlin, Germany, 2001), today not for sale, was the first implant navigation system introduced on the market and made the history of dynamic surgery; X-Guide (Nobel Biocare, 2017), a dynamic computer assisted system that uses the principles of stereoscopic triangulation by optical video cameras. Read More

View Article

Download full-text PDF

Source

Enalapril and treadmill running reduce adiposity, but only the latter causes adipose tissue browning in mice.

J Cell Physiol 2020 Jul 2. Epub 2020 Jul 2.

Laboratory of Exercise Sciences, Fluminense Federal University, Niteroi, Rio de Janeiro, Brazil.

This study investigated whether regulation of the renin-angiotensin system (RAS) by enalapril and/or aerobic exercise training (AET) causes browning of the subcutaneous white adipose tissue (sWAT). C57BL/6 mice were fed either a standard chow or a high-fat (HF) diet for 16 weeks. At Week 8, HF-fed animals were divided into sedentary (HF), enalapril (HF-E), AET (HF-T), and enalapril plus AET (HF-ET) groups. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.29900DOI Listing

Impacts of low salinity exposure and antibiotic application on gut transport activity in the Pacific spiny dogfish, Squalus acanthias suckleyi.

J Comp Physiol B 2020 Jul 2. Epub 2020 Jul 2.

Department of Biological Sciences, University of Manitoba, Winnipeg, MB, R3T 2N2, Canada.

The role of the marine elasmobranch gastrointestinal tract in nitrogen-recycling and osmotic homeostasis has become increasingly apparent, with the gut microbial community likely playing a significant role converting urea, an important osmolyte in elasmobranchs, into ammonia. The Pacific spiny dogfish can experience and tolerate reduced environmental salinities, yet how this environmental challenge may affect the microbiome, and consequently nitrogen transport across the gut, is as of yet unknown. In the present study, excised gut sac preparations were made from dogfish acclimated to the following: full-strength seawater (C), low salinity for 7 days (LS), and after acute transfer of LS-acclimated fish to full-strength SW for 6 h (AT). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00360-020-01291-4DOI Listing

Black PRAISE: engaging Black congregations to strengthen critical awareness of HIV affecting Black Canadian communities.

Health Promot Int 2020 Jul 2. Epub 2020 Jul 2.

Meritus Medical Centre, Inc., 11116 Medical Campus Road, Suite 2904, Hagerstown, MD 21742, USA.

In Canada, HIV disproportionately affects Black communities. Though Black faith leaders play an influential role engaging Black communities around social care and social justice, their response to HIV has been somewhat muted. Black PRAISE is a novel intervention for Black churches to strengthen congregants' critical awareness of HIV affecting Black communities. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/heapro/daaa057DOI Listing

Influences for Gender Disparity in Academic Family Medicine in North American Medical Schools.

Cureus 2020 May 30;12(5):e8368. Epub 2020 May 30.

Radiology, Vancouver General Hospital, Vancouver, CAN.

Background Women physicians continue to comprise the minority of leadership roles in Academic Family Medicine (AFM) faculty across North American medical schools. Our study quantified the current state of gender disparity by analyzing academic position, leadership ranking, and research productivity. Methods We generated a database for 6,746 AFM faculty members. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.8368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326302PMC

Recognition of Advanced Practice Pharmacists in Australia and Beyond: Considerations for Canadian Practitioners.

Can J Hosp Pharm 2020 May-Jun;73(3):225-231. Epub 2020 Jun 1.

, BPharm, MClinPharm, AdvPracPharm, is with the Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308161PMC

Practical Guidance in Perioperative Management of Immunosuppressive Therapy for Rheumatology Patients Undergoing Elective Surgery.

Can J Hosp Pharm 2020 May-Jun;73(3):218-224. Epub 2020 Jun 1.

, BPharm, MSc, RPh, is with The Ottawa Hospital, Ottawa, Ontario.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308162PMC

Vasopressin for Septic Shock in a Medical-Surgical Intensive Care Unit.

Can J Hosp Pharm 2020 May-Jun;73(3):209-215. Epub 2020 Jun 1.

, BSc, BSc(Pharm), ACPR, is with the Department of Pharmacy Services and the Department of Emergency Medicine, Surrey Memorial Hospital, Surrey, British Columbia.

Background: Critically ill patients often need vasopressors to treat hypotension related to septic shock and to maintain adequate systemic perfusion. Although the 2017 guidelines of the Surviving Sepsis Campaign recommend norepinephrine as first-line therapy, they also state that vasopressin may be considered as an adjunctive agent for patients with refractory shock. Limited evidence is available for directing optimal administration of vasopressin. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308152PMC

The identification of sulfide oxidation as a potential metabolism driving primary production on late Noachian Mars.

Sci Rep 2020 Jul 2;10(1):10941. Epub 2020 Jul 2.

AstrobiologyOU, Faculty of Science, Technology, Engineering and Mathematics, The Open University, Milton Keynes, UK.

The transition of the martian climate from the wet Noachian era to the dry Hesperian (4.1-3.0 Gya) likely resulted in saline surface waters that were rich in sulfur species. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-020-67815-8DOI Listing

Spatial distribution of gambling exposure and vulnerability: an ecological tool to support health inequality reduction.

Public Health 2020 Jun 30. Epub 2020 Jun 30.

School of Public Health, University of Montreal Department of Social and Preventive Medicine, 7101 Av du Parc, Montréal, Québec, H3N 1X9, Canada.

Objectives: Recent research by Public Health has redefined harmful gambling, shifting the focus from problematic people with irresponsible behaviour to 'gamblogenic' environments. The aim of this research was to support this alternative perspective with concrete ecological tools for characterizing harmful environments. Studies that analyse the spatial distribution of gambling show that people living in the most disadvantaged areas have greater access to gambling and are more affected by the harms of gambling. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.puhe.2020.03.023DOI Listing

Processing evaluation of random bred broiler populations and a common ancestor at 55 days under chronic heat stress conditions.

Poult Sci 2020 Jul 15;99(7):3491-3500. Epub 2020 Apr 15.

Division of Agriculture, University of Arkansas, Fayetteville, Arkansas 72701, USA.

As a result of genetic selection, the modern broiler is more efficient, higher yielding, and faster growing than the bird of the 1950s. Unfortunately, as a result of improvement in growth rate, the modern broiler has the potential to struggle under heat stress conditions. The present study evaluates 3 different random bred populations and a common ancestor under both a thermal neutral and heat stress conditions after a 54-D grow-out period. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.psj.2020.03.036DOI Listing

Conducting a Mixed-Methods Study with Older Adults in Five Languages: Lessons from the Field.

Can J Aging 2020 Jun 19:1-10. Epub 2020 Jun 19.

Centre for Hip Health and Mobility, University of British Columbia & Vancouver Coastal Health Research Institute, Vancouver.

One third of older adults in Canada are foreign-born, yet there is a dearth of literature on this population. When our team set out to engage in a mixed-methods study on the physical activity and mobility of foreign-born older adults (FBOAs), we found limited guidance. The objective of this Research Note is to share the lessons that we learned in implementing a mixed-methods study in five languages, with 49 visible minority FBOAs from diverse ethno-cultural groups. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0714980820000100DOI Listing

Dementia-Friendly Neighbourhoods in Canada: A Carer Perspective.

Can J Aging 2020 Jul 3:1-12. Epub 2020 Jul 3.

School of Social Work, University of Ottawa, Ottawa, Ontario.

Based on findings from a study examining the lived experiences of dementia carers in their neighbourhoods, this article offers a vision of what dementia-friendly communities could look like from a carer perspective and in a Canadian context. Twelve carers in Ottawa and its surrounding regions were interviewed using a combination of social network maps, mobile interviews, and participant-driven photography. The findings, organized according to the categories "relationships", "places", and "everyday practices", reveal that many of the carers' choices regarding businesses, services, home location, outings, and everyday practices, are based on a desire to maintain social connections and social citizenship. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0714980820000252DOI Listing

Clearing the air: A study of cannabis-related presentations to urban Alberta emergency departments following legalization.

CJEM 2020 Jun 19:1-8. Epub 2020 Jun 19.

Department of Emergency Medicine, University of Calgary, Calgary, AB.

Objectives: Non-medical cannabis recently became legal for adults in Canada. Legalization provides opportunity to investigate the public health effects of national cannabis legalization on presentations to emergency departments (EDs). Our study aimed to explore association between cannabis-related ED presentations, poison control and telemedicine calls, and cannabis legalization. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/cem.2020.384DOI Listing

Age-Friendly Communities and Cultural Pluralism: Examining Saskatoon's Chinese-Canadian Social Enclave.

Can J Aging 2020 Jun 19:1-12. Epub 2020 Jun 19.

Department of Geography and Planning, Queen's University.

This article uses findings from qualitative interviews to examine the experiences of members of Saskatoon's Chinese-Canadian older-adult community in terms of their realities of aging and access to important geriatric resources. Promoting an understanding of both group experience and a broader conceptualization of age-friendly development, we argue that the notion and implications of a spatial ethnic enclave are replaced in the Saskatoon context by a social enclave. This network of social support is evident in Chinese-Canadian older adults' access to housing, recreation, transportation, and health services. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0714980820000148DOI Listing

Complicated hospitalization due to influenza: results from the Global Hospital Influenza Network for the 2017-2018 season.

BMC Infect Dis 2020 Jul 2;20(1):465. Epub 2020 Jul 2.

Institute of Health Metrics and Evaluation, Department of Health Metrics Sciences, University of Washington, Seattle, WA, USA.

Background: Since 2011, the Global Influenza Hospital Surveillance Network (GIHSN) has used active surveillance to prospectively collect epidemiological and virological data on patients hospitalized with influenza virus infection. Here, we describe influenza virus strain circulation in the GIHSN participant countries during 2017-2018 season and examine factors associated with complicated hospitalization among patients admitted with laboratory-confirmed influenza illness.

Methods: The study enrolled patients who were hospitalized in a GIHSN hospital in the previous 48 h with acute respiratory symptoms and who had symptoms consistent with influenza within the 7 days before admission. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12879-020-05167-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330273PMC

National Competencies for Registered Nurses in Primary Care: A Delphi Study.

West J Nurs Res 2020 Jul 3:193945920935590. Epub 2020 Jul 3.

Centre for Health Services and Policy Research and School of Nursing, University of British Columbia, Vancouver, BC, Canada.

A Delphi (consensus) process was used to obtain national agreement on competencies for registered nurses (RNs) in primary care. A draft of competencies was developed by key informants. Following this, nurses with primary care experience/expertise completed a Delphi survey to rate the importance of competency statements on a six-point Likert scale. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0193945920935590DOI Listing

Measuring treatment outcome in children with developmental coordination disorder; responsiveness of six outcome measures.

Disabil Rehabil 2020 Jul 2:1-12. Epub 2020 Jul 2.

Basalt Rehabilitation, Leiden/The Hague, The Netherlands.

Although measuring outcome of rehabilitation in children with Developmental Coordination Disorder is considered important no consensus exists on which instruments to use. An important attribute of a measurement instrument would be that it is sensitive to clinical changes. The aim of this prospective, observational study was therefore to investigate the responsiveness of six potentially suitable instruments. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/09638288.2020.1785022DOI Listing

Between Exploration, Pleasure, and Performance: Sexual Enhancement Medication Use among Older Gay and Heterosexual Men.

J Sex Res 2020 Jul 2:1-9. Epub 2020 Jul 2.

Sexology Department, Université du Québec à Montréal.

Pharmaceutical marketing campaigns and biomedical discourses tend to oppose two types of sexual enhancement medication (SEM) use. While "therapeutic" use is associated with older heterosexual men in committed relationships, "recreational" use is associated with young gay men, and with the context of casual sex. However, little is known about the real objectives of older men (especially older gay men) who use SEM or the contexts in which they use such drugs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/00224499.2020.1786661DOI Listing

COVID-19 Pandemic on Canadian Radiology Residency Education-Impact and Solutions: University of Toronto Perspective.

Can Assoc Radiol J 2020 Jul 2:846537120940299. Epub 2020 Jul 2.

Department of Medical Imaging, University of Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0846537120940299DOI Listing

Evaluation of the SNAP® 4Dx® plus test for the detection of Dirofilaria immitis antigen and characterization of exposure to tick-borne pathogens in wild canids in southern Ontario.

Vet Parasitol 2020 Jun 25;283:109176. Epub 2020 Jun 25.

Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario, N1G 2W1, Canada.

Population-level surveys for Dirofilaria immitis in wild canids typically rely on identification of the parasite at necropsy. More recently, some studies have employed the use of the SNAP® 4Dx® Plus test. However, since the assay was designed for use with domestic dogs it needs to be validated for use with wild canids for accurate interpretation of results. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vetpar.2020.109176DOI Listing

Rapid review methods more challenging during COVID-19: Commentary with a focus on 8 knowledge synthesis steps.

J Clin Epidemiol 2020 Jun 29. Epub 2020 Jun 29.

Knowledge Translation Program, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, 209 Victoria Street, East Building, Toronto, ON, M5B 1T8, Canada; Department of Geriatric Medicine, University of Toronto, 27 King's College Circle, Toronto, ON, M5S 1A1, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jclinepi.2020.06.029DOI Listing
June 2020
3.417 Impact Factor

Neural Oscillations and Brain Stimulation in Alzheimer's Disease.

Prog Neurobiol 2020 Jun 29:101878. Epub 2020 Jun 29.

Department of Neuroscience, Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, AB, T1K 3M4, Canada. Electronic address:

Aging is associated with alterations in cognitive processing and brain neurophysiology. Whereas the primary symptom of amnestic mild cognitive impairment (aMCI) is memory problems greater than normal for age and education, patients with Alzheimer's disease (AD) show impairments in other cognitive domains in addition to memory dysfunction. Resting-state electroencephalography (rsEEG) studies in physiological aging indicate a global increase in low-frequency oscillations' power and the reduction and slowing of alpha activity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pneurobio.2020.101878DOI Listing

Cortical Bone Porosity in Rabbit Models of Osteoporosis.

J Bone Miner Res 2020 Jul 2. Epub 2020 Jul 2.

Department of Anatomy, Physiology, and Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

Cortical bone porosity is intimately linked with remodeling, is of growing clinical interest, and is increasingly accessible by imaging. Thus, the potential of animal models of osteoporosis (OP) to provide a platform for studying how porosity develops and responds to interventions is tremendous. To date, rabbit models of OP have largely focused on trabecular microarchitecture or bone density; some such as ovariectomy (OVX) have uncertain efficacy and cortical porosity has not been extensively reported. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbmr.4124DOI Listing

Using machine learning to quantify structural MRI neurodegeneration patterns of Alzheimer's disease into dementia score: Independent validation on 8,834 images from ADNI, AIBL, OASIS, and MIRIAD databases.

Hum Brain Mapp 2020 Jul 2:e25115. Epub 2020 Jul 2.

School of Engineering Science, Simon Fraser University, Barnaby, British Columbia, Canada.

Biomarkers for dementia of Alzheimer's type (DAT) are sought to facilitate accurate prediction of the disease onset, ideally predating the onset of cognitive deterioration. T1-weighted magnetic resonance imaging (MRI) is a commonly used neuroimaging modality for measuring brain structure in vivo, potentially providing information enabling the design of biomarkers for DAT. We propose a novel biomarker using structural MRI volume-based features to compute a similarity score for the individual's structural patterns relative to those observed in the DAT group. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.25115DOI Listing

Translating Outcome Frameworks to Assessment Programs: Implications for Validity.

Med Educ 2020 Jul 2. Epub 2020 Jul 2.

Centre for Simulation Based Learning and Department of Medicine, McMaster University, Hamilton, On, Canada.

Introduction: Competency based medical education (CBME) requires that educators structure assessment of clinical competence using outcome frameworks. While these frameworks may serve some outcomes well (e.g. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/medu.14287DOI Listing

Association of Atrial Fibrillation Episode Duration With Arrhythmia Recurrence Following Ablation: A Secondary Analysis of a Randomized Clinical Trial.

JAMA Netw Open 2020 Jul 1;3(7):e208748. Epub 2020 Jul 1.

Montreal Heart Institute, Department of Medicine, Université de Montréal, Montréal, Quebec, Canada.

Importance: Contemporary guidelines recommend that atrial fibrillation (AF) be classified based on episode duration, with these categories forming the basis of therapeutic recommendations. While pragmatic, these classifications are not based on pathophysiologic processes and may not reflect clinical outcomes.

Objective: To evaluate the association of baseline AF episode duration with post-AF ablation arrhythmia outcomes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamanetworkopen.2020.8748DOI Listing