16,967 results match your criteria Campylobacter Infections
Front Microbiol 2018 16;9:2674. Epub 2018 Nov 16.
Food Animal Health Research Program, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH, United States.
Chemotaxis-mediated motility enables to navigate through complex environmental gradients and colonize diverse niches. is known to possess several methyl accepting chemotaxis proteins (MCPs), also called transducer-like proteins (Tlps). While the role of some of the Tlps in chemotaxis has been identified, their regulation and role in virulence is still not very clear. Read More
Cell Chem Biol 2018 Nov 2. Epub 2018 Nov 2.
Department of Chemistry and Biology, Ryerson University, Toronto, ON M5B 2K3, Canada. Electronic address:
We have developed an Escherichia coli strain for the in vivo production of O-glycosylated proteins. This was achieved using a dual plasmid approach: one encoding a therapeutic protein target, and a second encoding the enzymatic machinery required for O-glycosylation. The latter plasmid encodes human polypeptide N-acetylgalactosaminyl transferase as well as a β1,3-galactosyl transferase and UDP-Glc(NAc)-4-epimerase, both from Campylobacter jejuni, and a disulfide bond isomerase of bacterial or human origin. Read More
Clin Infect Dis 2018 Dec 4. Epub 2018 Dec 4.
Sections of Pediatric Emergency Medicine and Gastroenterology, Department of Pediatrics, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Background: The ability to identify bacterial pathogens that necessitate specific clinical management or public health action in children with acute gastroenteritis is crucial to patient care and public health. However, existing stool testing guidelines offer inconsistent recommendations, and their performance characteristics are unknown. We evaluated six leading gastroenteritis guidelines (e. Read More
Mol Nutr Food Res 2018 Dec 4:e1800947. Epub 2018 Dec 4.
A. Podany, J. Rauchut, D. I. Soybel, S. L Kelleher, Department of Surgery, Penn State Hershey College of Medicine, Hershey, Pennsylvania.
Scope: Greater than 68% of young infants are exposed to dietary zinc (Zn) levels that are higher than the Tolerable Upper Intake Limit. However, the consequences of excess dietary Zn during early life on intestinal function and host-microbe interactions are unknown.
Methods And Results: Neonatal mice were gavaged with 100 Zn μg/d from post-natal day (PN) 2 through PN10 and indices of intestinal function and host-microbe interactions were compared to unsupplemented mice. Read More
Infect Immun 2018 Dec 3. Epub 2018 Dec 3.
Pathobiology and Population Sciences, Royal Veterinary College, Hawkshead Lane, North Mymms, AL9 7TA, UK.
can cause the disease coccidiosis in chickens. The direct and often detrimental impact of this parasite on chicken health, welfare and productivity is well recognised, however less is known about the secondary effects infection may have on other gut pathogens. is the leading cause of human bacterial food-borne disease in many countries and has been demonstrated to exert negative effects on poultry welfare and production in some broiler lines. Read More
Int J Food Microbiol 2018 Nov 20;291:151-160. Epub 2018 Nov 20.
National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Centre for Zoonoses and Environmental Microbiology, Netherlands. Electronic address:
In previous work, extreme survival of various bacterial species during cooking was reported when attached to chicken meat. In this paper the effects of an extremely high challenge temperature on survival of Salmonella Typhimurium and Campylobacter jejuni, attached to chicken breast fillets or pork to test for matrix effects are reported. Survival was predicted, using standard D- and z-values from the literature, and compared to experimentally obtained data. Read More
Food Microbiol 2019 Apr 14;78:82-88. Epub 2018 Sep 14.
Department of Food Hygiene and Environmental Health, Faculty of Veterinary Medicine, University of Helsinki, Finland.
Hunting is currently a very popular activity, and interest in game meat is increasing. However, only limited research is available on the bacterial quality and safety of moose (Alces alces) and white-tailed deer (Odocoileus virginianus) harvested by hunters. Poor hunting hygiene can spread bacteria onto the carcasses, and inadequate chilling of the carcasses may increase the bacterial load on the carcass surface. Read More
Food Microbiol 2019 Apr 1;78:53-61. Epub 2018 Oct 1.
German Federal Institute for Risk Assessment (BfR), Department of Biological Safety, National Reference Laboratory for Campylobacter, Berlin, Germany. Electronic address:
Quantification of Campylobacter is challenging and one major reason is the fact that bacteria lose cultivability due to cold or oxygen stress during storage at retail. Alternative live/dead discriminatory qPCR currently lacks standardization and might overestimate live cells in the presence of dead cells. In this study an internal sample process control (ISPC) was developed. Read More
Curr Microbiol 2018 Nov 28. Epub 2018 Nov 28.
Poultry Microbiological Safety and Processing Research Unit, U.S. National Poultry Research Center, Agricultural Research Service, U.S. Department of Agriculture, 950 College Station Road, Athens, GA, 30605-2720, USA.
Poultry production is a major agricultural output worldwide. It is known that the gut health of broilers is essential for their growth and for providing wholesome products for human consumption. Previously, the microbial diversity of broiler ceca was studied at the genetic level. Read More
Infect Dis (Lond) 2018 Nov 29:1-7. Epub 2018 Nov 29.
a Department of Veterinary Pathology and Public Health, Faculty of Veterinary Medicine , Jordan University of Science and Technology , Irbid , Jordan.
Background: This is the first large-scale cross-sectional study to examine Campylobacter jejuni seropositivity in Jordan.
Methods: A total of 368 serum samples from nine governorates of Jordan were tested for IgA and IgG antibodies using enzyme-linked immunosorbent assay along with data collection to determine and rank possible risk factors by logistic regression analyses.
Results: The results showed that the rate of seroprevalence is 13. Read More
Asian Pac J Cancer Prev 2018 Nov 29;19(11):3211-3216. Epub 2018 Nov 29.
Department of Microbiology of Pathobiology, School of Public Health, Tehran University of Medical Sciences, International Campus (TUMS-IC), Tehran, Iran.
Background: Barrett’s oesophagus (BO) is a pre-malignant condition in which normal squamous epithelium of the lower oesophagus and gastresophageal junction is replaced by columnar cells and progress to oesophageal adenocarcinoma. The increase burden of oesophagus cancer morbidity and mortality worldwide make study of factors involved in the pathogenesis of BO essential. However, most of studies that examine the environmental risk factors associated with increased incidence and prevalence of BO have largely ignored the potential role of bacteria in disease aetiology. Read More
J Basic Microbiol 2018 Nov 28. Epub 2018 Nov 28.
Department of Zoology, Abdul Wali Khan University, Garden Campus, Mardan, Pakistan.
Bacteriophages (phages/viruses) need host bacteria to replicate and propagate. Primarily, a bacteriophage contains a head/capsid to encapsidate the genetic material. Some phages contain tails. Read More
JGH Open 2018 Jun 15;2(3):93-96. Epub 2018 May 15.
Division of Gastroenterology, Department of Internal Medicine Mackay Memorial Hospital Taipei Taiwan.
Background And Aim: To assess the detection rates of colonization in the gastric cardia with two commercial kits of rapid urease test: 5 min UFT300 and 24 h CLO test in H. pylori-infected patients.
Methods: Eighty consecutive dyspeptic patients with confirmed H. Read More
J Cell Physiol 2018 Nov 27. Epub 2018 Nov 27.
Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Irritable bowel syndrome (IBS) is a prolonged and disabling functional gastrointestinal disorder with the incidence rate of 18% in the world. IBS could seriously affect lifetime of patients and cause high economic burden on the community. The pathophysiology of the IBS is hardly understood, whereas several possible mechanisms, such as visceral hypersensitivity, irregular gut motility, abnormal brain-gut relations, and the role of infectious agents, are implicated in initiation and development of this syndrome. Read More
IDCases 2018 13;14:e00468. Epub 2018 Nov 13.
Department of Microbiology, University Hospitals Plymouth NHS Trust, Derriford Hospital, Plymouth PL6 8DH, UK.
Campylobacter are common zoonotic food borne pathogens but infrequent causes of disseminated human infection. is an unusual cause of human infection and spondylodiscitis. We describe a case of infection in a 72-year-old woman who presented with indolent onset lumbar spondylodiscitis. Read More
Protein Cell 2018 Nov 26. Epub 2018 Nov 26.
MOE Key Laboratory of Bioinformatics and TCM-X center/Bioinformatics Division, BNRist/Department of Automation, Tsinghua University, Beijing, 100084, China.
The development of gastritis is associated with an increased risk of gastric cancer. Current invasive gastritis diagnostic methods are not suitable for monitoring progress. In this work based on 78 gastritis patients and 50 healthy individuals, we observed that the variation of tongue-coating microbiota was associated with the occurrence and development of gastritis. Read More
Curr Opin Microbiol 2018 Nov 23;47:32-37. Epub 2018 Nov 23.
Institute for Glycomics, Griffith University, Gold Coast, 4222, QLD, Australia. Electronic address:
Campylobacter jejuni is a ubiquitous gastrointestinal pathogen, transmitted to humans from birds and animals, where C. jejuni is part of normal intestinal flora. In C. Read More
Vet Microbiol 2018 Dec 9;227:112-118. Epub 2018 Aug 9.
Vaccine & Molecular Innovation RPT, University of Southern Queensland, Toowoomba, Australia. Electronic address:
Spotty Liver Disease is an acute infectious disease of layer chickens that was likely first described in the USA and Canada in the 1950s and 1960's. The disease occurs almost exclusively in barn and free-range production systems. Outbreaks usually, but not exclusively occur in young layers (≅25 weeks) at peak of lay. Read More
Mol Ther 2018 Oct 17. Epub 2018 Oct 17.
Fight against Angiogenesis-Related Blindness (FARB) Laboratory, Clinical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:
Genome editing with CRISPR systems provides an unprecedented opportunity to modulate cellular responses in pathological conditions by inactivating undruggable targets, such as transcription factors. Previously, we demonstrated that the smallest Cas9 ortholog characterized to date, from Campylobacter jejuni (CjCas9) targeted to Hif1a and delivered in an adeno-associated virus (AAV) vector, effectively suppressed pathological choroidal neovascularization in the mouse retina. Before implementation of CjCas9 as an in vivo therapeutic modality, it is essential to investigate the long-term effects of target gene disruption via AAV-mediated delivery of CjCas9 in vivo. Read More
Poult Sci 2018 Nov 20. Epub 2018 Nov 20.
Chair of Food Hygiene and Veterinary Public Health, Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Fr. R. Kreutzwaldi 56/3, 51014, Tartu, Estonia.
Broiler chicken meat is considered as the main source of foodborne Campylobacter infection. Campylobacter jejuni multilocus sequence type ST-5 has been previously identified as predominant among Latvian and Lithuanian broiler chicken meat products and is often isolated from Lithuanian patients with Campylobacter enteric infection. The market share of Lithuanian and Latvian origin fresh broiler chicken meat sold at Estonian retail is estimated close to 50%. Read More
J Ind Microbiol Biotechnol 2018 Nov 20. Epub 2018 Nov 20.
Graduate School of Engineering, Hokkaido University, N13 & W8, Kita-ku, Sapporo, Hokkaido, 060-8628, Japan.
Menaquinone is an obligatory component of the electron-transfer pathway in microorganisms. Its biosynthetic pathway was established by pioneering studies with Escherichia coli and it was revealed to be derived from chorismate by Men enzymes. However, we identified an alternative pathway, the futalosine pathway, operating in some microorganisms including Helicobacter pylori and Campylobacter jejuni, which cause gastric carcinoma and diarrhea, respectively. Read More
Foodborne Pathog Dis 2018 Nov 20. Epub 2018 Nov 20.
3 Department of Health Western Australia, Grace Vaughan House , Perth, Australia .
Introduction: Limited baseline retail surveys have been published over the past 10 years on Campylobacter in Australian chicken meat. This study generates quantitative baseline data to assist in risk assessment and management strategies.
Methods: Raw poultry products (n = 315) were purchased for a year (2016-2017) from retail supermarkets in metropolitan Perth, Western Australia (WA). Read More
Front Microbiol 2018 2;9:2454. Epub 2018 Nov 2.
Department of Food Science, University of Arkansas, Fayetteville, AR, United States.
Rapid molecular techniques that evaluate eggs for the presence of foodborne pathogens is an essential component to poultry food safety monitoring. Interestingly, it is not just table eggs that contribute to outbreaks of foodborne disease. Broiler layer production actively contributes to sustaining of foodborne pathogens within a flock. Read More
J AOAC Int 2018 Nov 19. Epub 2018 Nov 19.
Suzhou Tadpole Biotechnology Co., Ltd, 218 Xinghu St, Suzhou 215000, China.
Sci Rep 2018 Nov 19;8(1):16996. Epub 2018 Nov 19.
Department of Molecular Biology, Umeå University, 90187, Umea, Sweden.
Campylobacter jejuni is a prevalent human pathogen and a major cause of bacterial gastroenteritis in the world. In humans, C. jejuni colonizes the intestinal tract and its tolerance to bile is crucial for bacteria to survive and establish infection. Read More
Arch Microbiol 2018 Nov 17. Epub 2018 Nov 17.
Division of Bacterial and Parasitic Disease, National Institute of Animal Health, National Agriculture and Food Research Organization, 3-1-5 Kannondai, Tsukuba, Ibaraki, 305-0856, Japan.
Campylobacter jejuni is one of the most important causes of food-borne diseases in industrialized countries. Amino acids are an important nutrient source for this pathogen because it lacks enzymes related to glycolysis. However, the metabolic characteristics of C. Read More
J Microbiol Methods 2018 Nov 15;155:78-81. Epub 2018 Nov 15.
Guangzhou Center for Disease Control and Prevention, Guangzhou, China. Electronic address:
We investigated the efficacy of syringe filters and membrane filters with different pore sizes for recovering Campylobacter. A syringe filter with a 0.45 μm pore size achieved the highest recovery rate (0. Read More
BMC Res Notes 2018 Nov 16;11(1):816. Epub 2018 Nov 16.
Swiss Tropical and Public Health Institute, Basel, Switzerland.
Objectives: Acute gastroenteritis (AG) is a usually self-limiting, but common disease worldwide. In Europe, incidence estimates range from 0.3-1. Read More
Sci Total Environ 2018 Oct 23;654:190-196. Epub 2018 Oct 23.
Institut de Recerca de la Biodiversitat (IRBio) and Departament de Biologia Evolutiva, Ecologia i Ciències Ambientals, Universitat de Barcelona, 08028 Barcelona, Spain.
Reports of enteric bacteria in Antarctic wildlife have suggested its spread from people to seabirds and seals, but evidence is scarce and fragmentary. We investigated the occurrence of zoonotic enteric bacteria in seabirds across the Antarctic and subantarctic region; for comparison purposes, in addition to seabirds, poultry in a subantarctic island was also sampled. Three findings suggest reverse zoonosis from humans to seabirds: the detection of a zoonotic Salmonella serovar (ser. Read More
Foodborne Pathog Dis 2018 Nov;15(11):671-688
2 Department of Veterinary Sciences, Institute of Food Safety, Ludwig-Maximilians-University Munich (LMU) , Munich, Germany .
In recent years, vegetables gain consumer attraction due to their reputation of being healthy in combination with low energy density. However, since fresh produce is often eaten raw, it may also be a source for foodborne illness. The presence of antibiotic-resistant bacteria might pose a particular risk to the consumer. Read More
Trop Med Int Health 2018 Nov 16. Epub 2018 Nov 16.
Centre for Tropical Medicine, University of Brasília, Brasília, Federal District, Brazil.
Objective: To describe the factors associated with the development of Guillain-Barré syndrome, both infectious and non-infectious, during and after the A(H1N1) influenza pandemic in 2009 and the recent Zika virus epidemic in the Americas.
Method: Systematic review of literature on factors associated with the development of the Guillain-Barré syndrome published between 2007 and 2017 listed in EBSCO, MEDLINE, and LILACS databases. The quality of the studies was evaluated using the Newcastle Ottawa Scale. Read More
Bull Math Biol 2018 Nov 14. Epub 2018 Nov 14.
School of Mathematical Sciences, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Temporal evolution of a clonal bacterial population is modelled taking into account reversible mutation and selection mechanisms. For the mutation model, an efficient algorithm is proposed to verify whether experimental data can be explained by this model. The selection-mutation model has unobservable fitness parameters, and, to estimate them, we use an Approximate Bayesian Computation algorithm. Read More
Heliyon 2018 Nov 5;4(11):e00915. Epub 2018 Nov 5.
Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Laenggassstrasse 122, CH-3012 Bern, Switzerland.
Bovine mycotic abortion is sporadic and caused by different ubiquitous and opportunistic fungi. Recently, a broad spectrum of bacterial opportunists involved in bovine abortion was revealed by 16S rRNA gene amplicon sequencing. We hypothesized that fungal organisms potentially involved in bovine abortion also might remain undetected by conventional culture. Read More
Antimicrob Agents Chemother 2018 Nov 12. Epub 2018 Nov 12.
Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD, 21205, USA.
To determine phenotypic patterns of antibiotic resistance and epidemiology of drug-resistant spp. from a low-resource setting.A birth cohort of 303 was followed until 5 years of age. Read More
PLoS One 2018 9;13(11):e0206502. Epub 2018 Nov 9.
Facultad de Ciencias Veterinarias, Universidad de Concepción, Chillán, Chile.
A lack of knowledge of naturally occurring pathogens is limiting our ability to use the Antarctic to study the impact human-mediated introduction of infectious microorganisms have on this relatively uncontaminated environment. As no large-scale coordinated effort to remedy this lack of knowledge has taken place, we rely on smaller targeted efforts to both study present microorganisms and monitor the environment for introductions. In one such effort, we isolated Campylobacter species from fecal samples collected from wild birds in the Antarctic Peninsula and the sub-Antarctic island of South Georgia. Read More
Poult Sci 2018 Nov 8. Epub 2018 Nov 8.
Department of Poultry Science, University of Arkansas, Fayetteville, AR 72701, USA.
Campylobacter jejuni infection in humans is strongly associated with the consumption of contaminated poultry products. With increasing consumer demand for minimally processed and natural product, there is a need for novel intervention strategies for controlling C. jejuni. Read More
IDCases 2018 28;14:e00463. Epub 2018 Oct 28.
Department of Medicine, Cairns Hospital, 165 The Esplanade, Cairns, QLD, 4870, Australia.
We describe a case of bacteremia with endovascular involvement in an immunocompetent female patient. The patient was treated with high dose ciprofloxacin as an outpatient and recovered well. Read More
Front Microbiol 2018 23;9:2515. Epub 2018 Oct 23.
Departamento de Bioquímica, Biología Molecular y Genética, Facultad de Veterinaria, Universidad de Extremadura, Cáceres, Spain.
Thermotolerant species and are actually recognized as the major bacterial agent responsible for food-transmitted gastroenteritis. The most effective antimicrobials against are macrolides and some, but not all aminoglycosides. Among these, susceptibility to streptomycin is reduced by mutations in the ribosomal RPSL protein or by expression of ANT(6)-I aminoglycoside O-nucleotidyltransferases. Read More
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2018 Oct;40(5):630-636
Department of Nutrition & Food Hygiene,School of Public Health,Peking University Health Science Center, Beijing 100191,China.
Objective To investigate the associations of socioeconomic factors,nutrients intake,and gut microbiota of healthy pregnant women in the third trimester with gestational weight gain (GWG).Methods We recruited 98 pregnant women in the third trimester who had received antenatal care in the Department of Obstetrics Gynecology,Peking Union Medical College Hospital from October,2015 to May,2016. We collected socioeconomic information through a structured questionnaire covering age,ethnicity,height,pre-pregnancy weight,and education. Read More
Foodborne Pathog Dis 2018 Nov 7. Epub 2018 Nov 7.
1 Institute of Food and Environmental Hygiene, Faculty of Veterinary Medicine, Latvia University of Life Sciences and Technologies , Jelgava, Latvia .
The aim of the present study was to detect the prevalence and antimicrobial resistance of fecal indicators and major foodborne pathogens in feces of calves and to identify the factors associated with increased prevalence of resistant bacteria on farms. Altogether, 180 rectal swabs were collected from 18 farms in Latvia. Samples were investigated to detect the prevalence and antimicrobial resistance of Escherichia coli, Enterococcus spp. Read More
Transpl Infect Dis 2018 Nov 7:e13021. Epub 2018 Nov 7.
Nephrology and Transplantation Unit, John Hunter Hospital, Newcastle, NSW, Australia.
Background: Guillain-Barré syndrome (GBS) is a common ascending polyneuropathy in adults. It is often associated with preceding viral or diarrhoeal illness with cytomegalovirus (CMV), Epstein-Barr virus (EBV), or Campylobacter jejuni. Solid organ transplant recipients are more susceptible to opportunistic infections with CMV than the general population as a result of immunosuppressive therapies to prevent graft rejection. Read More
PLoS One 2018 5;13(11):e0206930. Epub 2018 Nov 5.
Department of Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan.
Long term effects of subtotal gastrectomy on gut microbiota modifications with subsequent metabolic profiles are limited. We aimed to investigate and compare long-term effects of metabolic profiles and microbiota status in early gastric cancer patients post curative subtotal gastrectomy to the controls. In this cross-sectional study, we analyzed type II diabetes mellitus and metabolic syndrome occurrence in two groups: 111 patients after curative subtotal gastrectomy with Billroth II (BII) anastomosis and Roux-en-Y gastrojejuno (RYGJ) anastomosis and 344 age-sex matched controls. Read More
Przegl Epidemiol 2018 ;72(3):337-348
Oddział Kliniczny Chirurgii Serca, Naczyń i Transplantologii CM UJ, KSS im. Jana Pawła II, Kraków
Introduction: Acute gastroenteritis (AGE) is considered one of the most common reasons for hospitalization and the third leading cause of death related to infectious diseases in children. The incidence and prevalence of campylobacteriosis is lower in Poland than in other parts of the European Union.
The Aim Of The Study: The aim of the study was to investigate the epidemiology and clinical features of AGE in hospitalized children. Read More
NPJ Vaccines 2018 31;3:53. Epub 2018 Oct 31.
1Department of Respiratory Medicine, Centre for Inflammation and Tissue Repair, University College London, London, UK.
The pneumococcal conjugate vaccine (PCV) strongly protects against vaccine serotypes, but the rapid expansion of non-vaccine serotype disease and the vaccine's high expense has reduced its overall impact. We have developed Protein Glycan Coupling Technology (PGCT) as a flexible methodology for making low-cost polysaccharide/protein glycoconjugates recombinantly in . We have used PGCT to make a recombinant PCV containing serotype 4 capsular polysaccharide linked to the proteins NanA, PiuA, and Sp0148. Read More
Zhonghua Yu Fang Yi Xue Za Zhi 2018 Oct;52(10):1072-1077
Key Laboratory of Food Safety Risk Assessment of Health, China National Center for Food Safety Risk Assessment, Beijing 100021, China.
is a major cause of food-borne gastroenteritis worldwide. While mortality is low when people was infected with , morbidity imparted by post-infectious sequelae such as Guillain-Barré syndrome and irritable bowel syndrome is significantly noteworthy. Although fluoroquinolones and macrolides were the first line drug for the treatment of infections, there is a tough challenge in clinical treatment with high antimicrobial resistant rate and multi antimicrobial resistance arise. Read More
Clin Gastroenterol Hepatol 2018 Oct 30. Epub 2018 Oct 30.
Division of Digestive and Liver Disease, Department of Medicine, Columbia University Medical Center, New York, New York; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden; Department of Pediatrics, Orebro University Hospital, Orebro, Sweden; Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, UK.
Background & Aims: Gastrointestinal infections have been associated with later development of inflammatory bowel diseases (IBD). However, studies have produced conflicting results. We performed a nationwide case-control study in Sweden to determine whether gastroenteritis is associated with the development of Crohn's disease (CD) or ulcerative colitis (UC). Read More
Front Microbiol 2018 16;9:2432. Epub 2018 Oct 16.
Infectious Diseases Unit, Assaf Harofeh Medical Center, Zerifin, Israel.
is responsible for 80% of infections in Israel, a country with a high incidence reaching 91/100,000 population. We studied the phylogeny, diversity and prevalence of virulence factors using whole genome sequencing (WGS) of a national sample of clinical, food, and animal isolates collected over a 10-year period (2003-2012). isolates ( = 263) were subject to WGS using Illumina sequencing (PE 250bpx2). Read More
Pediatr Rev 2018 Nov;39(11):533-541
Division of Pediatric Infectious Diseases, Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, MD.
J Inorg Biochem 2019 Jan 19;190:75-84. Epub 2018 Oct 19.
Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York YO10 5DD, UK. Electronic address:
A mimic of the tetradentate stealth siderophore salmochelin S1, was synthesised, characterised and shown to form Fe(III) complexes with ligand-to-metal ratios of 1:1 and 3:2. Circular dichroism spectroscopy confirmed that the periplasmic binding proteins CeuE and VctP of Campylobacter jejuni and Vibrio cholerae, respectively, bind the Fe(III) complex of the salmochelin mimic by preferentially selecting Λ-configured Fe(III) complexes. Intrinsic fluorescence quenching studies revealed that VctP binds Fe(III) complexes of the mimic and structurally-related catecholate ligands, such as enterobactin, bis(2, 3-dihydroxybenzoyl-l-serine) and bis(2, 3-dihydroxybenzoyl)-1, 5-pentanediamine with higher affinity than does CeuE. Read More
Jpn J Infect Dis 2018 Oct 31. Epub 2018 Oct 31.
Graduate School of Life and Environmental Sciences, Osaka Prefecture University.
Proper surveillance of Campylobacter jejuni and Campylobacter coli, major pathogens associated with human gastroenteritis, is necessary to tackle the increasing disease burden. To detect these pathogenic species, a variety of PCR assays have been developed. This study examined the sensitivity and specificity of 12 PCR assays targeting 23S rRNA, ceuE, lpxA, hipO, mapA, ask, and cdt genes of C. Read More