9,130 results match your criteria Campylobacter Infections


Effects of child and maternal Histo Blood Group Antigen status on symptomatic and asymptomatic enteric infections in early childhood.

J Infect Dis 2019 Feb 15. Epub 2019 Feb 15.

Division of Infectious Diseases & International Health, University of Virginia, Charlottesville, VA, USA.

Background: Histo blood group antigens (HBGAs) such as fucosyltransferase FUT2 and 3 may act as innate host factors that differentially influence susceptibility of individuals and their offspring to pediatric enteric infections.

Methods: In three community-based birth cohorts, FUT2 and FUT3 statuses were ascertained for mother-child dyads. qPCR panels tested 3,663 diarrheal and 18,148 asymptomatic stool samples for 29 enteropathogens. Read More

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http://dx.doi.org/10.1093/infdis/jiz072DOI Listing
February 2019

Virulence related genes and co-enteropathogens associated with clinical outcomes of enteropathogenic infections in children from Brazilian semiarid region: a case-control study of diarrhea.

J Clin Microbiol 2019 Feb 6. Epub 2019 Feb 6.

Institute of Biomedicine for Brazilian Semiarid, Federal University of Ceará, Fortaleza, Brazil,1315 Coronel Nunes de Melo, zipcode: 60430-270.

Enteropathogenic (EPEC) is a major cause of diarrhea in children from developing countries and presents high genetic variability. We aimed to characterize EPEC virulence-related gene (VRG) distribution and copathogens associated with diarrhea and nutrition-related outcomes in children from the low-income Brazilian semiarid region. A cross-sectional case-control study of diarrhea was conducted in 1,191 children aged 2-36 months old from the Northeast Region of Brazil. Read More

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http://dx.doi.org/10.1128/JCM.01777-18DOI Listing
February 2019
1 Read

Longitudinal Study on Shiga Toxin-producing and on Finnish Dairy Farms and in Raw Milk.

Appl Environ Microbiol 2019 Feb 1. Epub 2019 Feb 1.

Microbiology Research Unit, Finnish Food Safety Authority Evira, Helsinki, Finland

Shiga toxin-producing (STEC) and are notable health hazards associated with the consumption of raw milk. These bacteria may colonize the intestines of asymptomatic cattle and enter bulk tank milk via fecal contamination during milking.We studied the frequency of STEC O157:H7 and contamination in tank milk (n=785) and the in-line milk filters of milking machines (n=631) versus isolation from cattle feces (n=257) on three Finnish dairy farms for one year. Read More

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http://dx.doi.org/10.1128/AEM.02910-18DOI Listing
February 2019
1 Read

Older Adults and Parents of Young Children Have Different Handling Practices for Raw Poultry.

J Food Prot 2019 Feb;82(2):200-206

3 Kansas State University, 1310 Research Park Drive, Ice Hall, Manhattan, Kansas 66506, USA.

Salmonella and Campylobacter are among the most common causes of foodborne disease in the United States. Most illnesses are associated with eating raw or undercooked poultry or cross-contamination. Young children and older adults are more susceptible to contracting foodborne illness and have serious infections compared with other age groups. Read More

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http://dx.doi.org/10.4315/0362-028X.JFP-18-323DOI Listing
February 2019

Climate, human behaviour or environment: individual-based modelling of Campylobacter seasonality and strategies to reduce disease burden.

J Transl Med 2019 Jan 21;17(1):34. Epub 2019 Jan 21.

Institute of Infection and Global Health, Liverpool University, Liverpool, L69 7BE, UK.

Background: With over 800 million cases globally, campylobacteriosis is a major cause of food borne disease. In temperate climates incidence is highly seasonal but the underlying mechanisms are poorly understood, making human disease control difficult. We hypothesised that observed disease patterns reflect complex interactions between weather, patterns of human risk behaviour, immune status and level of food contamination. Read More

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http://dx.doi.org/10.1186/s12967-019-1781-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341592PMC
January 2019
2 Reads

Climate-driven QMRA model for selected water supply systems in Norway accounting for raw water sources and treatment processes.

Sci Total Environ 2019 Apr 4;660:306-320. Epub 2019 Jan 4.

Water and Environmental Engineering Group, Department of Civil Engineering, Institute for Marine Operations and Civil Engineering, Norwegian University of Science and Technology (NTNU) in Ålesund, Larsgårdsvegen 2, 6009 Ålesund, Norway.

Formulating effective management intervention measures for water supply systems requires investigation of potential long-term impacts. This study applies an integrated multiple regression, random forest regression, and quantitative microbial risk assessment (QMRA) modelling approach to assess the effect of climate-driven precipitation on pathogen infection risks in three drinking water treatment plants (WTPs) in Norway. Pathogen removal efficacies of treatment steps were calculated using process models. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2018.12.460DOI Listing
April 2019
1 Read

Monitoring the incidence and causes of diseases potentially transmitted by food in Australia: Annual report of the OzFoodNet network, 2012.

Authors:

Commun Dis Intell (2018) 2018 16;42. Epub 2018 Nov 16.

This report summarises the incidence of diseases potentially transmitted by food in Australia and details outbreaks associated with food in 2012. OzFoodNet sites reported 27,976 notifications of diseases or conditions that may be transmitted by food. The most commonly notified infections were Campylobacter (15,668 notifications), followed by Salmonella (11,249 notifications). Read More

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November 2018

Antimicrobial Susceptibility and Genomic Structure of Isolates.

Front Microbiol 2018 14;9:3067. Epub 2018 Dec 14.

Institute of Bacterial Infections and Zoonoses (IBIZ), Friedrich Loeffler Institute, Jena, Germany.

spp. are considered the most common bacterial cause of foodborne gastroenteritis in the world. The family includes the genus with the three species , , and as emergent enteropathogens and potential zoonotic agents. Read More

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http://dx.doi.org/10.3389/fmicb.2018.03067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302008PMC
December 2018
1 Read

The epidemiology of non-viral gastroenteritis in New Zealand children from 1997 to 2015: an observational study.

BMC Public Health 2019 Jan 5;19(1):18. Epub 2019 Jan 5.

Department of Paediatrics, University of Otago, PO Box 4345, Christchurch Mail Centre, Christchurch, 8140, New Zealand.

Background: Acute gastroenteritis is a substantial cause of hospitalization in children. Shigella, Salmonella, Campylobacter, Yersinia, enterotoxigenic Escherichia coli (ETEC), Giardia and Cryptosporidium are gastrointestinal pathogens that are notifiable in New Zealand (NZ). The impact of these infections in the pediatric population has not yet been analyzed. Read More

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http://dx.doi.org/10.1186/s12889-018-6229-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321731PMC
January 2019
1 Read

Characteristics of Campylobacter, Salmonella Infections and Acute Gastroenteritis in Older Adults in Australia, Canada, and the United States.

Clin Infect Dis 2019 Jan 2. Epub 2019 Jan 2.

Department of Epidemiology, Colorado School of Public Health, Aurora, CO, United States.

Background: The early detection of enteric infections in older adults is challenging because typical signs and symptoms of disease may be less common, absent, or overlooked. Understanding illness characteristics of enteric infections among older adults could improve the timeliness and accuracy of clinical diagnoses, thereby improving patient outcomes and increasing cases reported to surveillance.

Methods: This study describes illness characteristics (percentage reporting bloody diarrhea, fever, vomiting, abdominal pain, percentage hospitalized, duration of hospitalization, and duration of illness) among older adults (≥65 years) with acute gastroenteritis and culture-confirmed Campylobacter and nontyphoidal Salmonella infections in Australia, Canada, and the United States, and compares these characteristics with those among younger adults (25-64 years) and children (<5 years, 5-24 years). Read More

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http://dx.doi.org/10.1093/cid/ciy1142DOI Listing
January 2019
1 Read

Investigating locally relevant risk factors for infection in Australia: protocol for a case-control study and genomic analysis.

BMJ Open 2018 Dec 22;8(12):e026630. Epub 2018 Dec 22.

National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australian Capital Territory, Australia.

Introduction: The CampySource project aims to identify risk factors for human infection in Australia. We will investigate locally relevant risk factors and those significant in international studies in a case-control study. Case isolates and contemporaneous isolates from food and animal sources will be sequenced to conduct source attribution modelling, and findings will be combined with the case-control study in a source-assigned analysis. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-026630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318611PMC
December 2018
4 Reads

clade 3 isolates induce rapid cell death .

Appl Environ Microbiol 2018 Dec 21. Epub 2018 Dec 21.

Clinical Microbiology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden

are major human enteropathogens. show less genetic diversity than and cluster into three clades, of which clade 1 includes most human and farm animal isolates while environmental mainly belong to clades 2 and 3. Recently, we whole genome-sequenced eight clade 2 and 3 isolates cultivated from water, and here we studied their interaction with human HT-29 colon cancer cells compared to clinical clade 1 isolates. Read More

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http://dx.doi.org/10.1128/AEM.02993-18DOI Listing
December 2018
1 Read

Enhanced Systemic Response of Matrix Metalloproteinases and Their Regulators in and Patients.

Diagnostics (Basel) 2018 Dec 13;8(4). Epub 2018 Dec 13.

Department of Medical Sciences, Clinical Microbiology, Uppsala University, Dag Hammarskjölds väg 38, 75237 Uppsala, Sweden.

Campylobacters are major enteropathogens worldwide with a substantial financial burden. Matrix metalloproteinases (MMPs) are proteolytic metalloendopeptidases with ability to modify immune response and shown to be upregulated in patients with several tissue destructive diseases, including infections. We measured here serum concentrations of MMP-8 and MMP-9 together with their regulators myeloperoxidase (MPO), human neutrophil elastase (HNE), and tissue inhibitor of metalloproteinases (TIMP)-1 in 80 and 25 patients as well as in 27 healthy controls. Read More

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http://dx.doi.org/10.3390/diagnostics8040082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315616PMC
December 2018
1 Read

Antimicrobial properties of rosin acids-loaded nanoparticles against antibiotic-sensitive and antibiotic-resistant foodborne pathogens.

Artif Cells Nanomed Biotechnol 2018 Dec 7:1-9. Epub 2018 Dec 7.

a Institute of Sciences of Food Production , National Research Council (ISPA-CNR) , Bari , Italy.

Rosin acids (RA) from coniferous trees are used in folk medicine for healing various skin infections. Despite the antimicrobial potential of RA, their poor solubility in aqueous media may limit their use. In this work RA-loaded polyethylene glycol-poly(lactic-co-glycolic acid) nanoparticles (RA-NPs) with enhanced antimicrobial properties against foodborne bacterial pathogens were produced. Read More

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http://dx.doi.org/10.1080/21691401.2018.1496924DOI Listing
December 2018
2 Reads

Antibiotic resistance of Campylobacter jejuni isolates recovered from humans with diarrhoea in Turkey.

J Med Microbiol 2019 Feb 12;68(2):136-142. Epub 2018 Dec 12.

3​Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, USA.

Purpose: This study was aimed at investigating the occurrence and genetic mechanisms of resistance to ciprofloxacin, tetracycline and erythromycin in clinical isolates of Campylobacter jejuni recovered from human cases of acute gastroenteritis in Turkey.

Methodology: MIC values of each antibiotic were determined with the epsilometer test (E-test). Resistance genes/mutations were first screened by PCR and analysed by subsequent DNA sequencing. Read More

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http://dx.doi.org/10.1099/jmm.0.000890DOI Listing
February 2019
2 Reads

Determinants of sporadic infections in Denmark: a nationwide case-control study among children and young adults.

Clin Epidemiol 2018 21;10:1695-1707. Epub 2018 Nov 21.

Infectious Disease Epidemiology & Prevention, Statens Serum Institut, Copenhagen, Denmark,

Background: Each year more than 4,000 cases of campylobacteriosis are reported in Denmark, making it the most common bacterial gastrointestinal infection. Here we describe a case-control study to identify sources of infection with a focus on environmental factors.

Methods: From January to December 2016, we conducted a prospective case-control study among Danish persons aged 1-30 years. Read More

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http://dx.doi.org/10.2147/CLEP.S177141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255050PMC
November 2018
1 Read

Ciprofloxacin resistance among Campylobacter jejuni isolates obtained from shelter dogs in Texas.

Zoonoses Public Health 2018 Dec 9. Epub 2018 Dec 9.

Texas A&M University, College Station, Texas.

There are few epidemiologic studies on the shedding of Campylobacter among dogs in the United States, despite the potential public health implications. Our objectives were to estimate the prevalence of faecal Campylobacter shedding among Texas shelter dogs as detected by culture methods and to characterize the isolates by species and antimicrobial susceptibility. Using a cross-sectional study design, faecal samples were collected from 185 dogs in six animal shelters throughout Texas between May and December 2014. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/zph.12544
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http://dx.doi.org/10.1111/zph.12544DOI Listing
December 2018
14 Reads
2.065 Impact Factor

Impact of pre-travel consultation on clinical management and outcomes of travelers' diarrhea: a retrospective cohort study.

Trop Dis Travel Med Vaccines 2018 4;4:16. Epub 2018 Dec 4.

1Division of Infectious Diseases, Department of Medicine, Mayo Clinic, 200 1st St SW, Rochester, MN 55905 USA.

Background: International travelers are at high risk of acquiring travelers' diarrhea. Pre-travel consultation has been associated with lower rates of malaria, hepatitis, and human immunodeficiency virus (HIV) infections. The objective was to study the impact of pre-travel consultation on clinical management and outcomes of travelers' diarrhea. Read More

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http://dx.doi.org/10.1186/s40794-018-0076-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280521PMC
December 2018

Bacteriophages: an overview of the control strategies against multiple bacterial infections in different fields.

J Basic Microbiol 2019 Feb 28;59(2):123-133. Epub 2018 Nov 28.

Department of Zoology, Abdul Wali Khan University, Garden Campus, Mardan, Pakistan.

Bacteriophages (phages/viruses) need host bacteria to replicate and propagate. Primarily, a bacteriophage contains a head/capsid to encapsidate the genetic material. Some phages contain tails. Read More

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http://dx.doi.org/10.1002/jobm.201800412DOI Listing
February 2019
9 Reads
1.823 Impact Factor

The possible role of bacteria, viruses, and parasites in initiation and exacerbation of irritable bowel syndrome.

J Cell Physiol 2018 Nov 27. Epub 2018 Nov 27.

Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Irritable bowel syndrome (IBS) is a prolonged and disabling functional gastrointestinal disorder with the incidence rate of 18% in the world. IBS could seriously affect lifetime of patients and cause high economic burden on the community. The pathophysiology of the IBS is hardly understood, whereas several possible mechanisms, such as visceral hypersensitivity, irregular gut motility, abnormal brain-gut relations, and the role of infectious agents, are implicated in initiation and development of this syndrome. Read More

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http://doi.wiley.com/10.1002/jcp.27828
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http://dx.doi.org/10.1002/jcp.27828DOI Listing
November 2018
13 Reads
3.839 Impact Factor

Spotty Liver Disease: A review of an ongoing challenge in commercial free-range egg production.

Vet Microbiol 2018 Dec 9;227:112-118. Epub 2018 Aug 9.

Vaccine & Molecular Innovation RPT, University of Southern Queensland, Toowoomba, Australia. Electronic address:

Spotty Liver Disease is an acute infectious disease of layer chickens that was likely first described in the USA and Canada in the 1950s and 1960's. The disease occurs almost exclusively in barn and free-range production systems. Outbreaks usually, but not exclusively occur in young layers (≅25 weeks) at peak of lay. Read More

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http://dx.doi.org/10.1016/j.vetmic.2018.08.004DOI Listing
December 2018
2 Reads

A retrospective epidemiological analysis of shared risk factors for bovine trichomoniasis and bovine genital campylobacteriosis in La Pampa province (Argentina).

Prev Vet Med 2018 Dec 29;161:109-114. Epub 2018 Oct 29.

Department of Animal Production, School of Veterinary, University of Cordoba, 14071, Spain.

The venereal diseases bovine trichomoniasis (BT) and bovine genital campylobacteriosis (BGC) cause economic losses in endemic areas like La Pampa province in Argentina, where beef cattle are usually managed extensively. The eradication of both diseases is a priority in Argentine. The aim of this case-control study was to identify shared and specific risk factors of both diseases from the data obtained from the Provincial Program for the Control and Eradication of BT and BGC in La Pampa (PCE). Read More

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http://dx.doi.org/10.1016/j.prevetmed.2018.10.022DOI Listing
December 2018
7 Reads

Do humans spread zoonotic enteric bacteria in Antarctica?

Sci Total Environ 2019 Mar 23;654:190-196. Epub 2018 Oct 23.

Institut de Recerca de la Biodiversitat (IRBio) and Departament de Biologia Evolutiva, Ecologia i Ciències Ambientals, Universitat de Barcelona, 08028 Barcelona, Spain.

Reports of enteric bacteria in Antarctic wildlife have suggested its spread from people to seabirds and seals, but evidence is scarce and fragmentary. We investigated the occurrence of zoonotic enteric bacteria in seabirds across the Antarctic and subantarctic region; for comparison purposes, in addition to seabirds, poultry in a subantarctic island was also sampled. Three findings suggest reverse zoonosis from humans to seabirds: the detection of a zoonotic Salmonella serovar (ser. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2018.10.272DOI Listing
March 2019
1 Read

Antibiotic Resistance of Species in a Pediatric Cohort Study.

Antimicrob Agents Chemother 2019 Feb 29;63(2). Epub 2019 Jan 29.

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

The objective of this study was to determine the phenotypic patterns of antibiotic resistance and the epidemiology of drug-resistant spp. from a low-resource setting. A birth cohort of 303 patients was followed until 5 years of age. Read More

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http://dx.doi.org/10.1128/AAC.01911-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355604PMC
February 2019
8 Reads
4.480 Impact Factor

Guillain-Barré syndrome post renal transplant: A systematic review.

Transpl Infect Dis 2019 Feb 28;21(1):e13021. Epub 2018 Nov 28.

Nephrology and Transplantation Unit, John Hunter Hospital, Newcastle, NSW, Australia.

Background: Guillain-Barré syndrome (GBS) is a common ascending polyneuropathy in adults. It is often associated with preceding viral or diarrhoeal illness with cytomegalovirus (CMV), Epstein-Barr virus (EBV), or Campylobacter jejuni. Solid organ transplant recipients are more susceptible to opportunistic infections with CMV than the general population as a result of immunosuppressive therapies to prevent graft rejection. Read More

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http://doi.wiley.com/10.1111/tid.13021
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http://dx.doi.org/10.1111/tid.13021DOI Listing
February 2019
12 Reads

A recombinant conjugated pneumococcal vaccine that protects against murine infections with a similar efficacy to Prevnar-13.

NPJ Vaccines 2018 31;3:53. Epub 2018 Oct 31.

1Department of Respiratory Medicine, Centre for Inflammation and Tissue Repair, University College London, London, UK.

The pneumococcal conjugate vaccine (PCV) strongly protects against vaccine serotypes, but the rapid expansion of non-vaccine serotype disease and the vaccine's high expense has reduced its overall impact. We have developed Protein Glycan Coupling Technology (PGCT) as a flexible methodology for making low-cost polysaccharide/protein glycoconjugates recombinantly in . We have used PGCT to make a recombinant PCV containing serotype 4 capsular polysaccharide linked to the proteins NanA, PiuA, and Sp0148. Read More

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http://www.nature.com/articles/s41541-018-0090-4
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http://dx.doi.org/10.1038/s41541-018-0090-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208403PMC
October 2018
3 Reads

[Overview of resistance mechanisms in ].

Authors:
Y Bai S Y Ye F Q Li

Zhonghua Yu Fang Yi Xue Za Zhi 2018 Oct;52(10):1072-1077

Key Laboratory of Food Safety Risk Assessment of Health, China National Center for Food Safety Risk Assessment, Beijing 100021, China.

is a major cause of food-borne gastroenteritis worldwide. While mortality is low when people was infected with , morbidity imparted by post-infectious sequelae such as Guillain-Barré syndrome and irritable bowel syndrome is significantly noteworthy. Although fluoroquinolones and macrolides were the first line drug for the treatment of infections, there is a tough challenge in clinical treatment with high antimicrobial resistant rate and multi antimicrobial resistance arise. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0253-9624.2018.10.021DOI Listing
October 2018
1 Read

Gastrointestinal Infection Increases Odds of Inflammatory Bowel Disease in a Nationwide Case-Control Study.

Clin Gastroenterol Hepatol 2018 Oct 30. Epub 2018 Oct 30.

Division of Digestive and Liver Disease, Department of Medicine, Columbia University Medical Center, New York, New York; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden; Department of Pediatrics, Orebro University Hospital, Orebro, Sweden; Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, United Kingdom.

Background & Aims: Gastrointestinal infections have been associated with later development of inflammatory bowel diseases (IBD). However, studies have produced conflicting results. We performed a nationwide case-control study in Sweden to determine whether gastroenteritis is associated with the development of Crohn's disease (CD) or ulcerative colitis (UC). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15423565183102
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http://dx.doi.org/10.1016/j.cgh.2018.09.034DOI Listing
October 2018
11 Reads

Genomic Epidemiology of Transmission in Israel.

Front Microbiol 2018 16;9:2432. Epub 2018 Oct 16.

Infectious Diseases Unit, Assaf Harofeh Medical Center, Zerifin, Israel.

is responsible for 80% of infections in Israel, a country with a high incidence reaching 91/100,000 population. We studied the phylogeny, diversity and prevalence of virulence factors using whole genome sequencing (WGS) of a national sample of clinical, food, and animal isolates collected over a 10-year period (2003-2012). isolates ( = 263) were subject to WGS using Illumina sequencing (PE 250bpx2). Read More

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https://www.nature.com/articles/s41598-018-25764-3.pdf
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https://www.researchgate.net/publication/325047838_Genomic_e
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https://www.nature.com/articles/s41426-018-0045-x.pdf
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https://www.frontiersin.org/article/10.3389/fmicb.2018.02432
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http://dx.doi.org/10.3389/fmicb.2018.02432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198274PMC
October 2018
4 Reads

Infections in Children.

Pediatr Rev 2018 11;39(11):533-541

Division of Pediatric Infectious Diseases, Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1542/pir.2017-0285DOI Listing
November 2018
1 Read

Potential role of dengue virus, chikungunya virus and Zika virus in neurological diseases.

Mem Inst Oswaldo Cruz 2018 Oct 29;113(11):e170538. Epub 2018 Oct 29.

Instituto Evandro Chagas, Seção de Arbovirologia e Febres Hemorrágicas, Ananindeua, PA, Brasil.

This study showed that laboratory markers of recent infection by dengue, Zika or chikungunya arboviruses were detected in the biological samples of approximately one-third of patients with encephalitis, myelitis, encephalomyelitis or Guillain-Barré syndrome, in a surveillance programme in Piauí state, Brazil, between 2015-2016. Fever and myalgia had been associated with these cases. Since in non-tropical countries most infections or parainfectious diseases associated with the nervous system are attributed to herpesviruses, enteroviruses, and Campylobacter jejuni, the present findings indicate that in tropical countries, arboviruses may now play a more important role and reinforce the need for their surveillance and systematic investigation in the tropics. Read More

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http://dx.doi.org/10.1590/0074-02760170538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204615PMC
October 2018
31 Reads

Chemical composition of Acacia farnesiana (L) wild fruits and its activity against Mycobacterium tuberculosis and dysentery bacteria.

J Ethnopharmacol 2019 Feb 25;230:74-80. Epub 2018 Oct 25.

Universidad Autónoma de Nuevo León, Facultad de Ciencias Químicas, Av. Universidad S/N, Ciudad Universitaria, CP 66451 San Nicolás de los Garza, Nuevo León, Mexico. Electronic address:

Ethnopharmacological Relevance: In Mexico, plants are an important element of traditional medicine, and many are considered part of Mexican cultural heritage from prehispanic and colonial times. Nevertheless, relatively few systematic scientific studies have been conducted to fully characterize the chemical composition and pharmacological activities of Mexican medicinal plants. Acacia farnesiana is used in Mexican traditional medicine to treat dysentery and tuberculosis and therefore could have bioactive compounds that may explain its traditional use. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03788741183306
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http://dx.doi.org/10.1016/j.jep.2018.10.031DOI Listing
February 2019
15 Reads
2.998 Impact Factor

Synthesis of the Core Oligosaccharides of Lipooligosaccharides from Campylobacter jejuni: A Putative Cause of Guillain-Barré Syndrome.

Chemistry 2019 Jan 13;25(3):796-805. Epub 2018 Dec 13.

Department of Applied Bio-organic Chemistry, Gifu University, 1-1 Yanagido, Gifu-shi, Gifu, 501-1193, Japan.

The chemical synthesis of the highly branched core oligosaccharides of lipooligosaccharides (LOSs) found in Campylobacter jejuni, which causes Guillain-Barré syndrome by a preceding infection, is described. The target LOS mimics, consisting of eight or nine monosaccharides, were classified into three groups as key building blocks: ganglioside-core tetra-/pentasaccharides (GM1-/GD1a-like), l-glycero-d-manno-heptose-containing trisaccharides, and 3-deoxy-d-manno-2-octulosonic acid (KDO) residues. These synthetic fragments were obtained from commercially available monosaccharides. Read More

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http://doi.wiley.com/10.1002/chem.201804862
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http://dx.doi.org/10.1002/chem.201804862DOI Listing
January 2019
26 Reads

Review of Diagnostic Procedures and Approaches to Infectious Causes of Reproductive Failures of Cattle in Australia and New Zealand.

Front Vet Sci 2018 2;5:222. Epub 2018 Oct 2.

Department of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong, Hong Kong.

Infectious causes of reproductive failure in cattle are important in Australia and New Zealand, where strict biosecurity protocols are in place to prevent the introduction and spread of new diseases. ranks highly as an important cause of reproductive wastage along with fungal and bacterial infections. , a leading cause of abortion elsewhere in the world, is foreign, following successful programs to control and eradicate the disease. Read More

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http://dx.doi.org/10.3389/fvets.2018.00222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176146PMC
October 2018

Relation between broiler and human Campylobacter jejuni strains isolated in Belgium from 2011 to 2013.

J Appl Microbiol 2019 Jan 20;126(1):277-287. Epub 2018 Nov 20.

National Reference Laboratory for Campylobacter, Sciensano, Scientific Service Foodborne Pathogens, Brussels, Belgium.

Aims: This study inquires the relationship between Campylobacter jejuni isolated from broiler meat carcasses (n = 97) and human clinical samples (n = 72) in Belgium, from 2011 to 2013.

Methods And Results: The evaluation of the relation was based on the characteristics determined using multilocus sequence typing (MLST) alone and combined with flagellin gene A restriction fragment length polymorphism (flaA-RFLP) typing, antibiotic microbiological resistance profiling (AMRp), lipooligosaccharide class typing or virulence gene profiling (Vp). Clusters containing both human and broiler meat strains were more common when MLST was used alone, followed by MLST/flaA-RFLP and then by MLST/AMRp. Read More

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http://doi.wiley.com/10.1111/jam.14132
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http://dx.doi.org/10.1111/jam.14132DOI Listing
January 2019
6 Reads

Antibiotic Resistance Is the Key Element in Treatment of Helicobacter pylori Infection.

Authors:
Francis Mégraud

Gastroenterology 2018 11 8;155(5):1300-1302. Epub 2018 Oct 8.

INSERM U1053, University of Bordeaux and National Reference Center for Campylobacter and Helicobacter, CHU Bordeaux, Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2018.10.012DOI Listing
November 2018
1 Read

Genomic epidemiology of clinical Campylobacter spp. at a single health trust site.

Microb Genom 2018 Oct 11;4(10). Epub 2018 Oct 11.

5​University of Wolverhampton, Wolverhampton, UK.

Campylobacter is the leading cause of bacterial enteritis in the developed world, and infections with the organism are largely sporadic in nature. Links between sporadic cases have not been established, with the majority of infections thought to be caused by genetically distinct isolates. Using a read-mapping approach, 158 clinical isolates collected during 2014 from the greater Nottinghamshire area were analysed to assess the local population structure and investigate potential case linkages between sporadic cases of campylobacteriosis. Read More

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http://www.microbiologyresearch.org/content/journal/mgen/10.
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http://dx.doi.org/10.1099/mgen.0.000227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249439PMC
October 2018
1 Read

Commentary: Campylobacter and Hemolytic Uremic Syndrome.

Foodborne Pathog Dis 2019 Feb 10;16(2):90-93. Epub 2018 Oct 10.

Eastern Regional Research Center , Agricultural Research Service, U.S. Department of Agriculture, Wyndmoor, Pennsylvania.

There are reports in the literature stating that Campylobacter infections can cause hemolytic uremic syndrome (HUS); however, a mechanism for how Campylobacter induces HUS has not been proposed by investigators. The most common bacterial inducer of HUS is the Shiga toxin-producing Escherichia coli (STEC), and a few cases of HUS are induced by an invasive Shigella dysenteriae or Streptococcus pneumoniae infection. Campylobacter spp. Read More

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https://www.liebertpub.com/doi/10.1089/fpd.2018.2513
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http://dx.doi.org/10.1089/fpd.2018.2513DOI Listing
February 2019
2 Reads

Use of quantitative molecular diagnostic methods to assess the aetiology, burden, and clinical characteristics of diarrhoea in children in low-resource settings: a reanalysis of the MAL-ED cohort study.

Lancet Glob Health 2018 Dec 1;6(12):e1309-e1318. Epub 2018 Oct 1.

Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA.

Background: Optimum management of childhood diarrhoea in low-resource settings has been hampered by insufficient data on aetiology, burden, and associated clinical characteristics. We used quantitative diagnostic methods to reassess and refine estimates of diarrhoea aetiology from the Etiology, Risk Factors, and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) cohort study.

Methods: We re-analysed stool specimens from the multisite MAL-ED cohort study of children aged 0-2 years done at eight locations (Dhaka, Bangladesh; Vellore, India; Bhaktapur, Nepal; Naushero Feroze, Pakistan; Venda, South Africa; Haydom, Tanzania; Fortaleza, Brazil; and Loreto, Peru), which included active surveillance for diarrhoea and routine non-diarrhoeal stool collection. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S2214109X183034
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http://dx.doi.org/10.1016/S2214-109X(18)30349-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6227251PMC
December 2018
10 Reads
1 Citation

Use of quantitative molecular diagnostic methods to investigate the effect of enteropathogen infections on linear growth in children in low-resource settings: longitudinal analysis of results from the MAL-ED cohort study.

Lancet Glob Health 2018 Dec 1;6(12):e1319-e1328. Epub 2018 Oct 1.

Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA. Electronic address:

Background: Enteropathogen infections in early childhood not only cause diarrhoea but contribute to poor growth. We used molecular diagnostics to assess whether particular enteropathogens were associated with linear growth across seven low-resource settings.

Methods: We used quantitative PCR to detect 29 enteropathogens in diarrhoeal and non-diarrhoeal stools collected from children in the first 2 years of life obtained during the Etiology, Risk Factors, and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) multisite cohort study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S2214109X183035
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http://dx.doi.org/10.1016/S2214-109X(18)30351-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6227248PMC
December 2018
23 Reads
1 Citation

Synthesis of the Campylobacter jejuni 81-176 Strain Capsular Polysaccharide Repeating Unit Reveals the Absolute Configuration of its O-Methyl Phosphoramidate Motif.

Angew Chem Int Ed Engl 2018 Nov 19;57(47):15592-15596. Epub 2018 Oct 19.

Department of Chemistry, University of Alberta, Edmonton, Alberta, T6G 2G2, Canada.

The O-methyl phosphoramidate (MeOPN) motif is a non-stoichiometric modification of capsular polysaccharides (CPS) in ≈70 % of all Campylobacter jejuni strains. Infections by C. jejuni lead to food-borne illnesses and the CPS they produce are key virulence factors. Read More

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http://doi.wiley.com/10.1002/anie.201810222
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http://dx.doi.org/10.1002/anie.201810222DOI Listing
November 2018
5 Reads

The prevalence of spp. in vegetables, fruits, and fresh produce: a systematic review and meta-analysis.

Gut Pathog 2018 27;10:41. Epub 2018 Sep 27.

2Nutrition Research Center, Department of Food Hygiene and Quality Control, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.

There are a number of reports indicating correlation between outbreaks of campylobacteriosis and the consumption of raw vegetables. This study is a meta-analysis on the prevalence of in fresh vegetables and fruits without any location limitation, which was performed through a documented review of the available resources. Relevant literature was reviewed by trained reviewers, who examined the results for the inclusion of articles in the meta-analysis. Read More

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https://gutpathogens.biomedcentral.com/articles/10.1186/s130
Publisher Site
http://dx.doi.org/10.1186/s13099-018-0269-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158901PMC
September 2018
11 Reads

Antimicrobial susceptibility of clinical isolates of Campylobacter jejuni from New South Wales, Australia.

J Glob Antimicrob Resist 2018 Sep 26;16:76-80. Epub 2018 Sep 26.

School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia. Electronic address:

Objectives: The aim of this study was to investigate the prevalence of resistance to commonly used antimicrobials in Campylobacter jejuni isolates from clinical faecal samples in New South Wales (NSW), Australia.

Methods: A total of 117 C. jejuni isolates from human faecal samples from regional and metropolitan NSW were examined for antimicrobial resistance. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22137165183018
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http://dx.doi.org/10.1016/j.jgar.2018.09.011DOI Listing
September 2018
9 Reads

Update on Campylobacter vaccine development.

Hum Vaccin Immunother 2018 Sep 25:1-12. Epub 2018 Sep 25.

a Enteric Diseases Department , Naval Medical Research Center , Silver Spring , MD , USA.

Background: Acute diarrheal disease caused by viral, bacterial and parasitic infections are a major global health problem with substantial mortality and morbidity in children under five years of age in lower and middle income countries. However, a number of these infections also impact large segments of populations in upper income countries, as well as individuals who travel overseas for work, business or pleasure. Campylobacter has been and continues to be a leading cause of disease burden globally across all income countries. Read More

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http://dx.doi.org/10.1080/21645515.2018.1528410DOI Listing
September 2018
1 Read

I could have consulted fishermen.

Authors:
A Schattner

QJM 2018 09;111(9):673

From the Faculty of Medicine, Hebrew University and Hadassah Medical School, Jerusalem, Israel.

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https://academic.oup.com/qjmed/article/111/9/673/3056733
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http://dx.doi.org/10.1093/qjmed/hcx056DOI Listing
September 2018
1 Read

Feed Choice Led to Higher Protein Intake in Broiler Chickens Experimentally Infected With .

Front Nutr 2018 5;5:79. Epub 2018 Sep 5.

Evonik Nutrition & Care GmbH, Hanau, Germany.

In 2016, was the most commonly reported gastrointestinal bacterial pathogen in humans in the European Union with 246,307 reported cases. Of these cases, 83.6% were . Read More

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http://dx.doi.org/10.3389/fnut.2018.00079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134014PMC
September 2018

Genetic and Antibiotic Resistance Characteristics of Campylobacter jejuni Isolated from Diarrheal Patients, Poultry and Cattle in Shenzhen.

Biomed Environ Sci 2018 Aug;31(8):579-585

Nanshan Center for Disease Control and Prevention, Shenzhen 518054, Guangdong, China.

Objective: To investigate genetic and antibiotic resistance characteristics of Campylobacter jejuni (C. jejuni) isolated from Shenzhen.

Methods: Multilocs sequence typing and agar dilution methods were used to define the genotype and antibiotic resistance of C. Read More

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http://dx.doi.org/10.3967/bes2018.079DOI Listing
August 2018
2 Reads

Clinical application of a multiplex genetic pathogen detection system remaps the aetiology of diarrhoeal infections in Shanghai.

Gut Pathog 2018 11;10:37. Epub 2018 Sep 11.

1Department of Laboratory Medicine, Huadong Hospital, Affiliated with Fudan University, Shanghai, 200040 China.

Background: Culture-based diagnostic methods cannot achieve rapid and precise diagnoses for the identification of multiple diarrhoeal pathogens (DPs). A high-throughput multiplex genetic detection system (HMGS) was adapted and evaluated for the simultaneous identification and differentiation of infectious DPs and a broad analysis of DP infection aetiology.

Results: DP-HMGS was highly sensitive and specific for DP detection compared with culture-based techniques and was similar to singleplex real-time PCR. Read More

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http://dx.doi.org/10.1186/s13099-018-0264-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134694PMC
September 2018
6 Reads

Proficiency of WHO Global Foodborne Infections Network External Quality Assurance System Participants in Identification and Susceptibility Testing of Thermotolerant Campylobacter spp. from 2003 to 2012.

J Clin Microbiol 2018 Nov 25;56(11). Epub 2018 Oct 25.

WHO Collaborating Centre for Antimicrobial Resistance in Foodborne Pathogens and European Union Reference Laboratory for Antimicrobial Resistance, National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.

spp. are foodborne and waterborne pathogens. While rather accurate estimates for these pathogens are available in industrialized countries, a lack of diagnostic capacity in developing countries limits accurate assessments of prevalence in many regions. Read More

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http://dx.doi.org/10.1128/JCM.01066-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204681PMC
November 2018