9,885 results match your criteria Campylobacter Infections

How does feedback from phage infections influence the evolution of phase variation in Campylobacter?

PLoS Comput Biol 2021 Jun 14;17(6):e1009067. Epub 2021 Jun 14.

Department of Mathematics, University of Leicester, Leicester, United Kingdom.

Campylobacter jejuni (C. jejuni) causes gastroenteritis following the consumption of contaminated poultry meat, resulting in a large health and economic burden worldwide. Phage therapy is a promising technique for eradicating C. Read More

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Rapid determination of viable but non-culturable Campylobacter jejuni in food products by loop-mediated isothermal amplification coupling propidium monoazide treatment.

Int J Food Microbiol 2021 Aug 1;351:109263. Epub 2021 Jun 1.

Food Nutrition and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, BC V6T 1Z4, Canada; Department of Food Science and Agricultural Chemistry, Faculty of Agricultural and Environmental Sciences, McGill University, Ste Anne de Bellevue, QC H9X 3V9, Canada. Electronic address:

Campylobacter is the leading cause of foodborne human diarrhea worldwide. This microbe in the viable but non-culturable (VBNC) state can evade detection by routinely used culture-based methods and remain viable for extended periods of time. Bacteria in this dormancy state can resume their metabolic activity and virulence by resuscitation under favorable conditions, and subsequently cause infections. Read More

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Mixtures of natural antimicrobials can reduce Campylobacter jejuni, Salmonella enterica and Clostridium perfringens infections and cellular inflammatory response in MDCK cells.

Gut Pathog 2021 Jun 7;13(1):37. Epub 2021 Jun 7.

Food Microbiology, Bacteriology Branch, Veterinary Sciences Division, Agri-Food and Biosciences Institute, 18a Newforge Lane, Belfast, BT9 5PX, Northern Ireland, UK.

Background: The classification of natural antimicrobials as potential antibiotic replacements is still hampered by the absence of clear biological mechanisms behind their mode of action. This study investigated the mechanisms underlying the anti-bacterial effect of a mixture of natural antimicrobials (maltodextrin, citric acid, sodium citrate, malic acid, citrus extract and olive extract) against Campylobacter jejuni RC039, Salmonella enterica SE 10/72 and Clostridium perfringens ATCC® 13124 invasion of Madin-Darby Canine Kidney cells (MDCK).

Results: Minimum sub-inhibitory concentrations were determined for Campylobacter jejuni (0. Read More

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Prevalence and impact of antimicrobial resistance in gastrointestinal infections: A review.

Rev Gastroenterol Mex 2021 Jun 3. Epub 2021 Jun 3.

Hospital Civil Fray Antonio Alcalde, Guadalajara, Jalisco, México.

Antimicrobial resistance has become a worldwide problem due to its excessive increase in recent years. The aim of the present review was to bring together data from different articles describing the levels of antimicrobial resistance in the most common gastrointestinal infections reported across the globe. The literature search was carried out in Google Scholar, Medline, Embase, and Pubmed, with the terms "antimicrobial resistance", "resistance in gastrointestinal disorders", and "resistance in amoebiasis", in Spanish and English. Read More

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Whole genome sequencing data used for surveillance of infections: detection of a large continuous outbreak, Denmark, 2019.

Euro Surveill 2021 Jun;26(22)

Statens Serum Institut, Department of Bacteria, Parasites and Fungi, Copenhagen, Denmark.

Background is one of the most frequent causes of bacterial gastroenteritis. outbreaks are rarely reported, which could be a reflection of a surveillance without routine molecular typing. We have previously shown that numerous small outbreak-like clusters can be detected when whole genome sequencing (WGS) data of clinical isolates was applied. Read More

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Transcriptomic analysis of caecal tissue in inbred chicken lines that exhibit heritable differences in resistance to Campylobacter jejuni.

BMC Genomics 2021 Jun 4;22(1):411. Epub 2021 Jun 4.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.

Background: Campylobacter jejuni is the leading cause of bacterial gastroenteritis in humans and the handling or consumption of contaminated poultry meat is a key source of infection. Selective breeding of poultry that exhibit elevated resistance to Campylobacter is an attractive control strategy. Here we studied the global transcriptional response of inbred chicken lines that differ in resistance to C. Read More

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Survey of Pathogen-Lowering and Immuno-Modulatory Effects Upon Treatment of -Infected Secondary Abiotic IL-10 Mice with the Probiotic Formulation Aviguard.

Microorganisms 2021 May 23;9(6). Epub 2021 May 23.

Gastrointestinal Microbiology Research Group, Institute of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 12203 Berlin, Germany.

The prevalence of infections with the zoonotic enteritis pathogen is increasing. Probiotic formulations constitute promising antibiotic-independent approaches to reduce intestinal pathogen loads and modulate pathogen-induced immune responses in the infected human host, resulting in acute campylobacteriosis and post-infectious sequelae. Here, we address potential antipathogenic and immuno-modulatory effects of the commercial product Aviguard during experimental campylobacteriosis. Read More

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Garlic Essential Oil as Promising Option for the Treatment of Acute Campylobacteriosis-Results from a Preclinical Placebo-Controlled Intervention Study.

Microorganisms 2021 May 25;9(6). Epub 2021 May 25.

Gastrointestinal Microbiology Research Group, Institute of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 12203 Berlin, Germany.

Since human infections with including antibiotic-resistant strains are rising worldwide, natural compounds might constitute promising antibiotics-independent treatment options for campylobacteriosis. Since the health-beneficial properties of garlic have been known for centuries, we here surveyed the antimicrobial and immune-modulatory effects of garlic essential oil (EO) in acute experimental campylobacteriosis. Therefore, secondary abiotic IL-10 mice were orally infected with strain 81-176 and garlic-EO treatment via the drinking water was initiated on day 2 post-infection. Read More

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One-Day Molecular Detection of and in Chicken Meat: A Pilot Study.

Foods 2021 May 19;10(5). Epub 2021 May 19.

Department of Food Safety, Istituto Zooprofilattico della Lombardia e dell'Emilia Romagna, Via A. Bianchi, 9, 25124 Brescia, Italy.

and ssp. are bacterial pathogens responsible for most foodborne infections in EU countries. Poultry serves as a reservoir for these pathogens, and its important role in the meat industry makes it essential to develop a rapid detection assay able to provide results in one day. Read More

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The Use of Probiotics in the Reduction of spp. Prevalence in Poultry.

Animals (Basel) 2021 May 10;11(5). Epub 2021 May 10.

Department of Poultry Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 13, 10-719 Olsztyn, Poland.

spp. are widely distributed microorganisms, many of which are commensals of gastrointestinal tract in multiple animal species, including poultry. Most commonly detected are and . Read More

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A one-year descriptive epidemiology of zoonotic abortifacient pathogen bacteria in farm animals in Turkey.

Comp Immunol Microbiol Infect Dis 2021 Aug 15;77:101665. Epub 2021 May 15.

Selcuk University, Department of Microbiology, Faculty of Veterinary Medicine, Konya, Turkey. Electronic address:

This study aimed to investigate the epidemiology of 10 suspicious pathogenic bacteria in 250 stomach contents of aborted calf, lamb, and goat foetuses in 2019. The 155 positive samples obtained from PCR consisted of 53 (58.88 %) bacteria from 90 lamb samples, 10 (43. Read More

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Antibiotic Testing and Successful Treatment of Hospitalized Patients with Extensively Drug-Resistant (XDR) Campylobacter jejuni Infections Linked to a Pet Store Puppy Outbreak.

J Glob Antimicrob Resist 2021 May 25. Epub 2021 May 25.

Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, GA.

Objectives: Most patients with Campylobacter infections do not require antibiotics; however, they are indicated in severe cases. Clinical breakpoints for many antibiotics have not yet been established by the Clinical and Laboratory Standards Institute, making antibiotic selection for resistant infections challenging. During an outbreak of pet store puppy-associated extensively drug resistant (XDR) Campylobacter jejuni infections resistant to seven classes of antibiotics, several patients required antibiotics. Read More

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Campylobacter jejuni ST50, a pathogen of global importance: A comparative genomic analysis of isolates from Australia, Europe and North America.

Zoonoses Public Health 2021 May 27. Epub 2021 May 27.

National Centre for Epidemiology and Population Health, The Australian National University, Canberra, ACT, Australia.

Campylobacter jejuni is the leading cause of bacterial gastroenteritis globally, and infections are often transmitted through consumption of raw or undercooked poultry. Campylobacter jejuni ST50 is among the top ten sequence types (STs) reported in the collected isolates listed at PubMLST records from poultry, food and clinical sources for Asia, Europe, North America, Oceania and South America. This study was designed to determine the most commonly reported C. Read More

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Antimicrobial Resistance of spp. Isolates from Broiler Chicken Meat Supply Chain in Maputo, Mozambique.

Foodborne Pathog Dis 2021 May 24. Epub 2021 May 24.

Section of Pharmacology and Toxicology, Department of Para-clinical Sciences, Veterinary Faculty, Eduardo Mondlane University, Maputo, Mozambique.

The transfer of antimicrobial-resistant bacterial strains from poultry products to humans has become a public health issue, a possible cause being the indiscriminate antibiotics use in poultry production. Therefore, in this study we examined the susceptibility of 24 isolates from broiler chicken carcasses from supermarkets, informal markets, and a slaughterhouse in Maputo, Mozambique, to 13 antibiotics. The results of the study showed that the isolates were resistant to at least six antibiotics in four classes. Read More

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Prevalence of intestinal parasitic infections and spp. among children with gastrointestinal disorders in Tehran, Iran.

Parasite Epidemiol Control 2021 May 14;13:e00207. Epub 2021 Feb 14.

Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.

Co-infection of intestinal parasitic infections (IPIs) and spp. are public health problem in both developing and developed countries. This study was conducted to determine prevalence of IPIs and spp. Read More

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Prevalence and antimicrobial profiling of Campylobacter spp. isolated from meats, animal, and human feces in Northern of Morocco.

Int J Food Microbiol 2021 Jul 27;349:109202. Epub 2021 Apr 27.

Biology and Health Laboratory, Biotechnology and Applied Microbiology Team, Department of Biology, Faculty of Science, Abdelmalek-Essaadi University, Tetouan, Morocco.

The present work was carried out to understand the occurrence and antimicrobial susceptibility of Campylobacter spp., in various samples in Northern of Morocco. For this purpose, a random sampling was undertaken from butcher shops, traditional markets, and slaughterhouse. Read More

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Coexistence of and in Campylobacter.

mSphere 2021 05 12;6(3). Epub 2021 May 12.

Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, Beijing Laboratory of Food Quality and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China

Previous studies indicated that has developed several mechanisms that confer resistance to florfenicol, which is used in food animal production. This study describes the coexistence of and in and isolates from pigs and poultry. Moreover, whole-genome sequencing data showed that the two genes are located in various multidrug resistance genomic islands within different regions of the genomes. Read More

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Enriched Opportunistic Pathogens Revealed by Metagenomic Sequencing Hint Potential Linkages between Pharyngeal Microbiota and COVID-19.

Virol Sin 2021 May 12. Epub 2021 May 12.

CAS Key Laboratory of Special Pathogens and Biosafety, Centre for Biosafety Mega-Sciences, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.

As a respiratory tract virus, SARS-CoV-2 infected people through contacting with the upper respiratory tract first. Previous studies indicated that microbiota could modulate immune response against pathogen infection. In the present study, we performed metagenomic sequencing of pharyngeal swabs from eleven patients with COVID-19 and eleven Non-COVID-19 patients who had similar symptoms such as fever and cough. Read More

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Using farm management practices to predict Campylobacter prevalence in pastured poultry farms.

Poult Sci 2021 Jun 11;100(6):101122. Epub 2021 Mar 11.

Department of Food Science and Technology, University of Georgia, Athens, GA, USA. Electronic address:

Contamination of poultry products by Campylobacter is often associated with farm management practices and processing plant practices. A longitudinal study was conducted on 11 pastured poultry farms in southeastern United States from 2014 to 2017. In this study, farm practices and processing variables were used as predictors for a random forest (RF) model to predict Campylobacter prevalence in pastured poultry farms and processing environments. Read More

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Comparative macrolide use in humans and animals: should macrolides be moved off the World Health Organisation's critically important antimicrobial list?

J Antimicrob Chemother 2021 May 6. Epub 2021 May 6.

Veterinary Medicine Research and Development, Zoetis, Inc, Kalamazoo, MI, USA.

Macrolide antibiotics are categorized by the WHO as Highest Priority, Critically Important Antimicrobials due to their recommendation as treatment for severe cases of campylobacteriosis in humans; a self-limiting, rarely life-threatening, zoonotic foodborne infection. Low rates of macrolide resistance in Campylobacter jejuni and the availability of alternative treatments have prompted some regulatory schemes to assign macrolides to a lower importance category. Apart from rare, specific infections, macrolides largely play a supportive role to other drug classes in human medicine. Read More

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Prevalence and antibiotic susceptibility trends of periodontal pathogens in the subgingival microbiota of German periodontitis patients: A retrospective surveillance study.

J Clin Periodontol 2021 May 2. Epub 2021 May 2.

Division of Microbiology, Paul-Ehrlich-Institut, Paul-Ehrlichstr. 51-59, D-63225, Langen, Germany.

Objective: This retrospective surveillance study aimed to follow periodontitis-associated bacterial profiles and to identify time-dependent changes in antibiotic susceptibility patterns.

Materials And Methods: From 2008 to 2015 bacterial specimen from deep periodontal pockets were collected from a total of 7804 German adults diagnosed with periodontitis. Presence of selected bacteria was confirmed by anaerobic culture and nucleic acid amplification. Read More

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Genome-wide screening of vaccine targets prioritization and reverse vaccinology aided design of peptides vaccine to enforce humoral immune response against Campylobacter jejuni.

Comput Biol Med 2021 Jun 18;133:104412. Epub 2021 Apr 18.

Department of Bioinformatics and Biological Statistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, PR China; Peng Cheng Laboratory, Vanke Cloud City Phase I Building 8, Xili Street, Nashan District, Shenzhen, Guangdong, 518055, PR China; State Key Laboratory of Microbial Metabolism, Shanghai-Islamabad-Belgrade Joint Innovation Center on Antibacterial Resistances, Joint Laboratory of International Cooperation in Metabolic and Developmental Sciences, Ministry of Education and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200030, PR China. Electronic address:

Campylobacter jejuni, gram-negative bacteria, is an infectious agent of foodborne disease-causing bloody diarrhea, abdominal pain, fever, Guillain-Barré syndrome (GBS) and Miller Fisher syndrome in humans. Campylobacter spp. with multidrug resistance to fluoroquinolones, tetracycline, and erythromycin are reported. Read More

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Application of a Physiologically Based Pharmacokinetic Model to Develop a Veterinary Amorphous Enrofloxacin Solid Dispersion.

Pharmaceutics 2021 Apr 22;13(5). Epub 2021 Apr 22.

National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues, Huazhong Agricultural University, Wuhan 430070, China.

Zoonotic intestinal pathogens threaten human health and cause huge economic losses in farming. Enrofloxacin (ENR) shows high antibacterial activity against common intestinal bacteria. However, its poor palatability and low aqueous solubility limit the clinical application of ENR. Read More

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Presence of and in Dogs under Training for Animal-Assisted Therapies.

Int J Environ Res Public Health 2021 04 2;18(7). Epub 2021 Apr 2.

Departments of Veterinary Medicine and Animal Productions, Federico II University of Naples, 80134 Naples, Italy.

This study was conducted to evaluate the presence of (C.) and in dogs at five dog training centers in Southern Italy. A total of 550 animals were sampled by collecting rectal swabs. Read More

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Modeling Enteropathy or Diarrhea with the Top Bacterial and Protozoal Pathogens: Differential Determinants of Outcomes.

ACS Infect Dis 2021 05 26;7(5):1020-1031. Epub 2021 Apr 26.

School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, United Kingdom.

Developing effective therapeutics or preventive interventions for important health threats is greatly enhanced whenever accessible models can enable the assessment of clinically important outcomes. While no non-human model is ever perfect, inexpensive small animal models in such as mice are often of great help in assessing the relevant efficacy of potential interventions. In addition to acute diarrhea, the long-term growth and developmental effects of enteric infections, with or without overt diarrhea, are increasingly recognized. Read More

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Detection of enteric bacteria in two groundwater sources and associated microbial health risks.

J Water Health 2021 Apr;19(2):322-335

Department of Microbiology, School of Sciences, Federal University of Technology, P.M.B 704 Akure, Ondo State, Nigeria E-mail:

The microbial quality of two groundwater sources (well and borehole) and associated risks were quantitatively assessed. Water samples from the selected borehole and well were collected over a period of 12 weeks (n = 48). The concentrations of Escherichia coli, faecal coliforms, Salmonella, Shigella, Clostridium, Bifidobacterium and Campylobacter were determined using standard microbiological methods, which involve the use of a membrane filter technique. Read More

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Bovine and Pig Carcasses as a Source of in Poland: A Reservoir for Antimicrobial-Resistant .

Foodborne Pathog Dis 2021 Apr 21. Epub 2021 Apr 21.

Department of Hygiene of Food of Animal Origin, National Veterinary Research Institute, Puławy, Poland.

is one of the most common causes of foodborne bacterial infections worldwide. Why poultry has been shown to be one of the most significant sources of these bacteria, ruminants, especially cattle, are also responsible for a high number of human , and to a lesser extent , infections. In this study, bovine and pig carcasses in Poland were investigated for the presence of and for their antimicrobial resistance. Read More

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Correction to: The Data Behind Risk Analysis of Campylobacter Jejuni and Campylobacter Coli Infections.

Curr Top Microbiol Immunol 2021 ;431:C1

Faculty of Veterinary Medicine, Institute for Veterinary Epidemiology and Biostatistics, Freie Universität Berlin, Berlin, Germany.

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January 2021

Quantification of Campylobacter jejuni gene expression after successive stresses mimicking poultry slaughtering steps.

Food Microbiol 2021 Sep 26;98:103795. Epub 2021 Mar 26.

SECALIM, INRAE, Oniris, Université Bretagne Loire, 44307, Nantes, France. Electronic address:

Broiler meat is considered as the most important source of the foodborne pathogen Campylobacter jejuni. Exposure to stress conditions encountered during the slaughtering process may induce bacterial adaptation mechanisms, and enhance or decrease pathogen resistance to subsequent stress. This adaptation may result from changes in bacterial gene expression. Read More

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September 2021

Hunted game birds - Carriers of foodborne pathogens.

Food Microbiol 2021 Sep 19;98:103768. Epub 2021 Feb 19.

Department of Food Hygiene and Environmental Health, Faculty of Veterinary Medicine, University of Helsinki, Finland.

Game birds may carry zoonotic bacteria in their intestines and transmit them to hunters through bird handling or through the handling and consumption of contaminated meat. In this study, the prevalence of foodborne bacteria was screened from game bird faeces and mallard breast meat using PCR. The sampling occurred in southern Finland from August to December during the hunting season. Read More

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September 2021