Int J Dermatol 2017 Apr 23. Epub 2017 Apr 23.
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Background: Untreated calciphylaxis is a fatal disease of intra- and extravascular calcification, most commonly presenting in end-stage renal disease (ESRD) patients. While early identification is critical for timely treatment, early-stage clinical and histopathological descriptions have not, to our knowledge, been elucidated. As early clinical recognition is essential to prompt definitive histopathological diagnosis, this study describes a range of clinical and histopathological manifestations of early-stage calciphylaxis. Read More