52,214 results match your criteria CV Surgery Online[Journal]


Optimization of operating conditions of miniaturize single chambered microbial fuel cell using NiWO/graphene oxide modified anode for performance improvement and microbial communities dynamics.

Bioresour Technol 2019 Apr 11;285:121337. Epub 2019 Apr 11.

School of Biochemical Engineering, Indian Institute of Technology (BHU), Varanasi, U.P. 221005, India. Electronic address:

NiWO and graphene oxide (NWG) modified anodic carbon cloth (CC) is used to improve the performance of single chambered microbial fuel cell (SMFC) by statistical optimization of operational parameters. The properties of synthesized NWG nanocomposite on the surface of modified anode are characterized by FTIR, XRD, EDX, TEM and SEM analysis. The optimum level of operational parameters maximize the power density (PD) 1458 mW/m of SMFC having NWG modified anode and observed 8. Read More

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http://dx.doi.org/10.1016/j.biortech.2019.121337DOI Listing

The up-regulation of proline synthesis in the meristematic tissues of wheat seedlings upon short-term exposure to osmotic stress.

J Plant Physiol 2019 Apr 4;237:21-29. Epub 2019 Apr 4.

Institute of Botany, University of Natural Resources and Life Sciences, Gregor Mendelstraße 33, 1180 Vienna, Austria. Electronic address:

An increase in the cellular concentration of free proline is a common response of many plants to various types of environmental stress. In this study, we monitored the accumulation of proline and the activities of Δ-pyrroline-5-carboxylate synthetase (P5CS) and Δ-pyrroline-5-carboxylate reductase (P5CR), the key enzymes of proline biosynthesis, in different parts of 4-day-old seedlings of wheat (Triticum aestivum L. cv. Read More

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http://dx.doi.org/10.1016/j.jplph.2019.03.010DOI Listing

Test-retest reliability of BSP, a battery of tests for assessing spatial cognition in visually impaired children.

PLoS One 2019 18;14(4):e0212006. Epub 2019 Apr 18.

Unit for Visually Impaired People, Center for Human Technologies, Fondazione Istituto Italiano di Tecnologia, Genoa, Italy.

Blind individuals are particularly dependent on their hearing for defining space. It has been found that both children and adults with visual impairments can struggle with complex spatial tasks that require a metric representation of space. Nonetheless the variability of methods employed to assess spatial abilities in absence of vision is wide, especially in the case of visually impaired children. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212006PLOS

Identification, Pathogenicity, and Spore Trapping of Associated with Twig and Shoot Dieback in California.

Plant Dis 2019 Apr 17:PDIS08181425RE. Epub 2019 Apr 17.

5 Department of Plant Pathology, University of California, Davis, CA 95616.

Corda, 1831 species are well-documented pathogens of citrus that are associated with leaf and fruit anthracnose diseases. However, their role in twig and shoot dieback diseases of citrus has recently become more prominent. Recent surveys of orchards in the Central Valley of California have revealed . Read More

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http://dx.doi.org/10.1094/PDIS-08-18-1425-REDOI Listing

An update on heart disease risk associated with testosterone boosting medications.

Expert Opin Drug Saf 2019 Apr 18. Epub 2019 Apr 18.

b Andrology, Female Endocrinology and Gender Incongruence Unit, Department of Experimental, Clinical and Biomedical Sciences , University of Florence , Florence , Italy.

Introduction: The cardiovascular (CV) safety of testosterone replacement therapy (TRT) remains a crucial issue in the management of subjects with late onset hypogonadism. The authors systematically reviewed and discussed the available evidence focusing our analysis on heart related issues. Areas covered: All the available data from prospective observational studies evaluating the role endogenous T levels on the risk of acute myocardial infarction (AMI) were collected and analyzed. Read More

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http://dx.doi.org/10.1080/14740338.2019.1607290DOI Listing

Elevated neutrophil to lymphocyte ratio as an indicator of secondary erythema nodosum, a retrospective observational study

Turk J Med Sci 2019 Apr 18;49(2):624-634. Epub 2019 Apr 18.

Background/aim: Erythema nodosum (EN) is an inflammatory disorder of subcutaneous tissue. Although etiopathogenesis of the disease is unknown, many predisposing factors such as infections, systemic disease, and drugs have been identified. Neutrophil to lymphocyte ratio (NLR) has been shown to be a novel inflammatory marker in many dermatological diseases. Read More

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http://dx.doi.org/10.3906/sag-1810-3DOI Listing

The Effect of Hormonal Contraception on Cervico-Vaginal Mucosal Endpoints associated with Human Immunodeficiency Virus Acquisition.

AIDS Res Hum Retroviruses 2019 Apr 18. Epub 2019 Apr 18.

Eastern Virginia Medical School, 6040, OB/GYN - CONRAD , 1911 N Fort Myer Dr , Arlington, Virginia, United States , 22209 ;

Objective: Reproductive age women may choose to concurrently use topical anti-retrovirals (ARVs) and hormonal contraceptives (HC) to simultaneously prevent human immunodeficiency virus type 1 (HIV-1) infection and unintended/mistimed pregnancy. There are conflicting data on the effect of HCs on mucosal susceptibility to HIV-1. The objective of this study was to evaluate cervico-vaginal (CV) mucosal data from healthy women before and after initiation of either oral contraceptive pills (OCPs) or depot medroxyprogesterone acetate injection (DMPA). Read More

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http://dx.doi.org/10.1089/AID.2018.0298DOI Listing

The effect of compressive force combined with mechanical vibration on human alveolar bone osteoblasts.

J Oral Biol Craniofac Res 2019 Jan-Mar;9(1):81-85. Epub 2018 Oct 16.

Orthodontic Section, Department of Preventive Dentistry, Faculty of Dentistry, Prince of Songkla University, Hat Yai, Songkhla, 90112, Thailand.

Objective: This study aimed to investigate the effects of compressive force combined with mechanical vibration on the expression of pro-inflammatory cytokines that promote osteoclastogenesis and related to orthodontic tooth movement acceleration in human alveolar bone osteoblasts .

Methods: Osteoblasts were subjected to compressive force (C), mechanical vibration (V), compressive force combined with mechanical vibration (CV), or no force as a control for 12, 24 and 48 h. Interleukin-1 beta (IL-1β), interleukin-6 (IL-6), receptor activator of nuclear factor kappa-Β ligand (RANKL) and osteoprotegerin (OPG) mRNA and protein expression were assessed using quantitative real-time polymerase chain reaction and enzyme-linked immunosorbent assays. Read More

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http://dx.doi.org/10.1016/j.jobcr.2018.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452925PMC
October 2018

Highlighting spin selectivity properties of chiral electrode surfaces from redox potential modulation of an achiral probe under an applied magnetic field.

Chem Sci 2019 Mar 4;10(9):2750-2757. Epub 2019 Jan 4.

Dipartimento di Chimica , Università degli Studi di Milano , via Golgi 19 , 20133 Milano , Italy . Email: ; Email: ; Email:

Impressive spin-related effects are observed in cyclic voltammetry (CV) experiments performed under an applied magnetic field on a non-ferromagnetic electrode modified with a thin electroactive oligothiophene film, either "inherently chiral" or featuring chiral pendants with stereogenic centres. When flipping the magnet's north/south orientation, the CV peaks of two achiral, chemically reversible Fe(iii)/Fe(ii) redox couples in aqueous or organic solution undergo impressive potential shifts (up to nearly 0.5 V depending on protocol conditions), specularly by changing the film's ()- or ()-configuration. Read More

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http://dx.doi.org/10.1039/c8sc04126aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419932PMC

Oxygen reactions on Pt{} in a non-aqueous Na electrolyte: site selective stabilisation of a sodium peroxy species.

Chem Sci 2019 Mar 17;10(10):2956-2964. Epub 2019 Jan 17.

Stephenson Institute for Renewable Energy , Department of Chemistry , University of Liverpool , UK . Email:

Sodium-oxygen battery cathodes utilise the reversible redox species of oxygen in the presence of sodium ions. However, the oxygen reduction and evolution reaction mechanism is yet to be conclusively determined. In order to examine the part played by surface structure in sodium-oxygen electrochemistry for the development of catalytic materials and structures, a method of preparing clean, well-defined Pt electrode surfaces for adsorption studies in aprotic solvents is described. Read More

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http://dx.doi.org/10.1039/c8sc05489dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427968PMC

Effects of ripening on the in vitro antioxidant capacity and bioaccessibility of mango cv. 'Ataulfo' phenolics.

J Food Sci Technol 2019 Apr 8;56(4):2073-2082. Epub 2019 Mar 8.

1Centro de Investigación en Alimentación y Desarrollo A.C. (CIAD A.C.) Unidad Hermosillo, Carretera Gustavo Enrique Astiazarán Rosas, No. 46, Hermosillo, Sonora Mexico.

Fruit ripening induces changes that strongly affect their matrices, and consequently, the bioaccessibility/bioavailability of its phenolic compounds. Flesh from 'slightly' (SR), 'moderately' (MR) and 'fully' (FR) ripe 'Ataulfo' mangoes were physicochemically characterized, and digested in vitro to evaluate how ripening impacts the bioaccessibility/bioavailability of its phenolic compounds. Ripening increased the flesh's pH and total soluble solids, while decreasing citric acid, malic acid and titratable acidity. Read More

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http://dx.doi.org/10.1007/s13197-019-03685-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443695PMC

Serum Erythroferrone Levels Associate with Mortality and Cardiovascular Events in Hemodialysis and in CKD Patients: A Two Cohorts Study.

J Clin Med 2019 Apr 16;8(4). Epub 2019 Apr 16.

CNR-IFC, Clinical Epidemiology of Renal Diseases and Hypertension, Reggio Cal Unit, 89126, Italy.

Erythroferrone (ERFE) is a hepcidin inhibitor whose synthesis is stimulated by erythropoietin, which increases iron absorption and mobilization. We studied the association between serum ERFE and mortality and non-fatal cardiovascular (CV) events in a cohort of 1123 hemodialysis patients and in a cohort of 745 stage 1-5 chronic kidney disease (CKD) patients. Erythroferrone was measured by a validated enzyme-linked immunosorbent assay (ELISA). Read More

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http://dx.doi.org/10.3390/jcm8040523DOI Listing

Machine-learning identifies parkinson's disease patients based on resting-state between-network functional connectivity.

Br J Radiol 2019 Apr 17:20180886. Epub 2019 Apr 17.

1 Department of Diagnostic and Interventional Radiology, University Dusseldorf, Medical Faculty , Dusseldorf , Germany.

Objectives: Evaluation of a data-driven, model-based classification approach to discriminate idiopathic Parkinson's disease (PD) patients from healthy controls (HC) based on between-network connectivity in whole-brain resting-state functional MRI (rs-fMRI).

Methods: Whole-brain rs-fMRI (EPI/TR = 2.2  s/TE = 30  ms/flip angle = 90°/resolution = 3. Read More

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http://dx.doi.org/10.1259/bjr.20180886DOI Listing

A single-base change at a splice site in Wx-A1 caused incorrect RNA splicing and gene inactivation in a wheat EMS mutant line.

Theor Appl Genet 2019 Apr 16. Epub 2019 Apr 16.

Triticeae Research Institute, Sichuan Agricultural University, Chengdu, 611130, Sichuan, China.

Key Message: An EMS-induced single-base mutation at a splice site caused abnormal RNA splicing and resulted in the gene inactivation and the lack of Wx-A1 protein in a wheat EMS mutant line. An EMS-mutagenized population was generated using common wheat cv. SM126 consisting of 10,600 M2 plants. Read More

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http://dx.doi.org/10.1007/s00122-019-03340-1DOI Listing

A randomized controlled trial of metformin on left ventricular hypertrophy in patients with coronary artery disease without diabetes: the MET-REMODEL trial.

Eur Heart J 2019 Apr 17. Epub 2019 Apr 17.

Division of Molecular and Clinical Medicine, School of Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK.

Aim: We tested the hypothesis that metformin may regress left ventricular hypertrophy (LVH) in patients who have coronary artery disease (CAD), with insulin resistance (IR) and/or pre-diabetes.

Methods And Results: We randomly assigned 68 patients (mean age 65 ± 8 years) without diabetes who have CAD with IR and/or pre-diabetes to receive either metformin XL (2000 mg daily dose) or placebo for 12 months. Primary endpoint was change in left ventricular mass indexed to height1. Read More

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https://academic.oup.com/eurheartj/advance-article/doi/10.10
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http://dx.doi.org/10.1093/eurheartj/ehz203DOI Listing
April 2019
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Advances in reducing cardiovascular risk in the management of patients with type 2 diabetes mellitus.

Authors:
Ying Hu

Chronic Dis Transl Med 2019 Mar 15;5(1):25-36. Epub 2019 Mar 15.

Department of Endocrinology, Lankenau Hospital, Main Line Health System, Wynnewood, PA 19096, USA.

Treatment intended to lower cardiovascular (CV) risk in patients with diabetes has always been a primary goal of diabetes treatment. Due to the subdued effects of reducing hemoglobin A1c (HbA1c) on macrovascular complications, controlling other CV risk factors such as hypertension and hyperlipidemia instead of hyperglycemia has been the mainstay treatment to improve CV outcome in patients with type 2 diabetes mellitus (T2DM) until recent years. This review is intended to summarize and compare the results from the available cardiovascular outcome trials (CVOTs) for the two classes of glucose lowering drug: sodium-glucose co-transporter 2 inhibitor (SGLT2i) and glucagon-like peptide-1 receptor agonist (GLP-1 RA). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S2095882X183006
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http://dx.doi.org/10.1016/j.cdtm.2019.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449766PMC
March 2019
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Nutrient removal and microalgal biomass production from different anaerobic digestion effluents with Chlorella species.

Sci Rep 2019 Apr 16;9(1):6123. Epub 2019 Apr 16.

School of Urban and Environmental Engineering, Ulsan National Institute of Science and Technology (UNIST), 50 UNIST-gil, Eonyang-eup, Ulju-gun, Ulsan, 44919, Republic of Korea.

Potential of microalgal cultivation as an alternative approach to the treatment of anaerobic digestion (AD) effluents was examined using two representative Chlorella species, Chlorella vulgaris (CV) and Chlorella protothecoides (CP). Both species effectively removed NH-N from the AD effluents from four digesters treating different wastes under different operating conditions. In all experimental cultures on the AD effluents, NH-N (initial concentration, 40 mg/L) was completely removed within 10 days without residual NO-N or NO-N in batch mode. Read More

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http://dx.doi.org/10.1038/s41598-019-42521-2DOI Listing

Precision of the Hologic DXA in the Assessment of Visceral Adipose Tissue.

J Clin Densitom 2019 Mar 20. Epub 2019 Mar 20.

Children's Hospital Oakland Research Institute, Oakland, CA, USA; Department of Hematology, UCSF Benioff Children's Hospital Oakland, Oakland, CA, USA. Electronic address:

Introduction: Visceral fat, also known as visceral adipose tissue (VAT), has been the focus of intensive research over the past several yr, as ground breaking studies have investigated its possible role in predicting long-term cardiac dysfunction, hypertension, and diabetes. Historically, magnetic resonance imaging and computed tomography were the instruments of choice for visceral fat quantification. However, with the introduction of visceral fat assessment software for Dual-energy X-ray Absorptiometry (DXA) scanners, DXA's use for VAT assessment has become increasingly common. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10946950193000
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http://dx.doi.org/10.1016/j.jocd.2019.03.005DOI Listing
March 2019
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Visit-to-visit fasting plasma glucose variability is an important risk factor for long-term changes in left cardiac structure and function in patients with type 2 diabetes.

Cardiovasc Diabetol 2019 Apr 16;18(1):50. Epub 2019 Apr 16.

Department of Endocrinology & Metabosim, Guangdong Provincial Key Laboratory of Diabetology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510630, China.

Background: To investigate the effect of visit-to-visit fasting plasma glucose (FPG) variability on the left cardiac structure and function in patients with type 2 diabetes mellitus (T2DM).

Methods: In this prospective cohort study, 455 T2DM patients were included and follow-up for a median of 4.7 years. Read More

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https://cardiab.biomedcentral.com/articles/10.1186/s12933-01
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http://dx.doi.org/10.1186/s12933-019-0854-9DOI Listing
April 2019
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Prevalence and long-term outcomes of non-alcoholic fatty liver disease among elderly individuals from the United States.

BMC Gastroenterol 2019 Apr 16;19(1):56. Epub 2019 Apr 16.

Betty and Guy Beatty Center for Integrated Research, Inova Health System, Claude Moore Health Education and Research Building, 3300 Gallows Road, Falls Church, VA, 22042, USA.

Background: The prevalence and outcomes of non-alcoholic fatty liver disease (NAFLD) among elderly have not been well described. Our aim was to assess the prevalence, risk factors and mortality of NAFLD in individuals older than 60 years.

Methods: The data from the Third National Health and Nutrition Examination Survey with linked mortality files were utilized. Read More

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http://dx.doi.org/10.1186/s12876-019-0972-6DOI Listing

Outcomes of Psychoeducation and a Text Messaging Adherence Intervention Among Individuals With Hypertension and Bipolar Disorder.

Psychiatr Serv 2019 Apr 17:appips201800482. Epub 2019 Apr 17.

Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).

Objective: This study evaluated the feasibility, acceptability, and preliminary efficacy of psychoeducation plus an automated text messaging intervention (Individualized Texting for Adherence Building-Cardiovascular [iTAB-CV]) to improve adherence to antihypertensives and bipolar disorder medication.

Methods: After a psychoeducation program, iTAB-CV was administered for 2 months. In month 1, participants received one educational-motivational and one mood rating text daily. Read More

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http://dx.doi.org/10.1176/appi.ps.201800482DOI Listing

Recovering cv. 'Lungo Fiorentino' Wastes: UHPLC-HRMS/MS Metabolic Profile, the Basis for Establishing Their Nutra- and Cosmeceutical Valorisation.

Molecules 2019 Apr 15;24(8). Epub 2019 Apr 15.

Department of Environmental Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", Via Vivaldi 43, I-81100 Caserta, Italy.

Food-waste is produced throughout all the food supply chain, with a large part already achieved at farm level. In fact, fruits and vegetables, which do not satisfy aesthetic demands, cannot be marketed, but their recovery could favour their valorisation for the obtainment of highly qualified goods. In this context, faulty zucchini fruits (cultivar 'Lungo Fiorentino'), intended for disposal, were rescued as effective, inexpensive and bio-sustainable source for cosmeceutical purposes. Read More

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http://dx.doi.org/10.3390/molecules24081479DOI Listing

Electro-sorption of ammonium ion onto nickel foam supported highly microporous activated carbon prepared from agricultural residues (dried Luffa cylindrica).

Sci Total Environ 2019 Apr 9;673:296-305. Epub 2019 Apr 9.

Department of Civil and Environmental Engineering, University of Delaware, Newark, DE 19716, USA. Electronic address:

An electrode made of loofah sponge derived activated carbon supported on nickel foam (AC/Ni) was successfully fabricated and used to remove ammonium ion (NH) from aqueous solution. A multilayer adsorption isotherm was used to describe ammonium electro-sorption on AC/Ni electrodes at different temperature, initial NH concentration, and electrical field. The cyclic voltammetry (CV) results suggested that the electrical capacitance of AC/Ni electrodes, with the AC being prepared without preheating (OAC) or with low temperature heating (i. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.04.066DOI Listing

Endogenous and exogenous effects of PGF2α during luteolysis in mares.

Theriogenology 2019 Apr 9;132:45-52. Epub 2019 Apr 9.

Eutheria Foundation, Cross Plains, WI, 53528, USA.

An inhibitor of PGF2α biosynthesis (flunixin meglumine, FM) was used to study the role of endogenous PGF2α on the luteolytic effect of exogenous PGF2α in mares. A 2-h infusion of PGF2α at a constant rate (total dose, 0.1 mg) on Day 10 (ovulation = Day 0) was used to mimic the maximal concentrations of a spontaneous pulse of a PGF2α metabolite (PGFM). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0093691X193009
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http://dx.doi.org/10.1016/j.theriogenology.2019.04.004DOI Listing
April 2019
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The shape-controlled synthesis of gallium-palladium (GaPd) nanomaterials as high-performance electrocatalysts for the hydrogen evolution reaction.

Nanoscale 2019 Apr 16. Epub 2019 Apr 16.

Department of Chemical Engineering, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu, Taiwan 30013, Republic of China.

Recently, great efforts have been focused on developing more active and stable Pd-based electrocatalysts to partially or completely replace rare and costly Pt. We developed a facile hot injection method and successfully synthesized well-dispersed and shape-controlled GaPd2 nanomaterials including polyhedrons, nanoparticles and nanowires. All the as-synthesized catalysts exhibit superior HER activity compared to commercial pure Pd catalysts and are stable in acidic media. Read More

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http://dx.doi.org/10.1039/c8nr10536gDOI Listing

Morning Surge and Peak Morning Ambulatory Blood Pressure Versus Automated Office Blood Pressure in Predicting Cardiovascular Disease.

High Blood Press Cardiovasc Prev 2019 Apr 15. Epub 2019 Apr 15.

Department of Cardiology, Georgetown University and Veterans Affairs Medical Center, Athens, Greece.

Introduction: Automated office blood pressure (AOBP) has been recently shown to predict equally well to ambulatory blood pressure (ABP), conventional office blood pressure (OBP) and home blood pressure (HBP), cardiovascular (CV) events among hypertensives.

Aim: To compare AOBP recording and ABP monitoring in order to evaluate morning blood pressure (BP) peak in predicting CV events and deaths in hypertensives.

Methods: We assessed 236 initially untreated hypertensives, examined between 2009 and 2013. Read More

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http://link.springer.com/10.1007/s40292-019-00315-7
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http://dx.doi.org/10.1007/s40292-019-00315-7DOI Listing
April 2019
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Standardization procedures for real-time breath analysis by secondary electrospray ionization high-resolution mass spectrometry.

Anal Bioanal Chem 2019 Apr 15. Epub 2019 Apr 15.

University Children's Hospital Basel, University of Basel, Spitalstr. 33, 4056, Basel, Switzerland.

Despite the attractiveness of breath analysis as a non-invasive means to retrieve relevant metabolic information, its introduction into routine clinical practice remains a challenge. Among all the different analytical techniques available to interrogate exhaled breath, secondary electrospray ionization high-resolution mass spectrometry (SESI-HRMS) offers a number of advantages (e.g. Read More

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http://dx.doi.org/10.1007/s00216-019-01764-8DOI Listing

Extracellular vesicle measurements with nanoparticle tracking analysis - An accuracy and repeatability comparison between NanoSight NS300 and ZetaView.

J Extracell Vesicles 2019 1;8(1):1596016. Epub 2019 Apr 1.

Experimental Tumor Research, Center for Tumor Biology and Immunology, Department of Hematology, Oncology and Immunology, Philipps University Marburg, Marburg, Germany.

The expanding field of extracellular vesicle (EV) research needs reproducible and accurate methods to characterize single EVs. Nanoparticle Tracking Analysis (NTA) is commonly used to determine EV concentration and diameter. As the EV field is lacking methods to easily confirm and validate NTA data, questioning the reliability of measurements remains highly important. Read More

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http://dx.doi.org/10.1080/20013078.2019.1596016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450530PMC

The Inter-Session Reliability of Isometric Force-Time Variables and the Effects of Filtering and Starting Force.

J Hum Kinet 2019 Mar 27;66:43-55. Epub 2019 Mar 27.

Exercise Science Department, East Stroudsburg University, East Stroudsburg, PA, 18301-2999, USA.

The purposes of the present study were to assess the inter-session reliability of force-time variables recorded during isometric back squats and also to assess the effects of applying a filter to the data prior to analysis and assess the effects of different starting force thresholds on the force-time variables. Eleven resistance trained men (age: 22.5 ± 1. Read More

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http://dx.doi.org/10.2478/hukin-2018-0049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458573PMC

The Metabolomic Signature of Opa1 Deficiency in Rat Primary Cortical Neurons Shows Aspartate/Glutamate Depletion and Phospholipids Remodeling.

Sci Rep 2019 Apr 15;9(1):6107. Epub 2019 Apr 15.

Equipe Mitolab, Institut MITOVASC, CNRS 6015, INSERM U1083, Université d'Angers, Angers, France.

Pathogenic variants of OPA1, which encodes a dynamin GTPase involved in mitochondrial fusion, are responsible for a spectrum of neurological disorders sharing optic nerve atrophy and visual impairment. To gain insight on OPA1 neuronal specificity, we performed targeted metabolomics on rat cortical neurons with OPA1 expression inhibited by RNA interference. Of the 103 metabolites accurately measured, univariate analysis including the Benjamini-Hochberg correction revealed 6 significantly different metabolites in OPA1 down-regulated neurons, with aspartate being the most significant (p < 0. Read More

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http://dx.doi.org/10.1038/s41598-019-42554-7DOI Listing

Gene expression analysis of vascular pathophysiology related to anti-TNF treatment in rheumatoid arthritis.

Arthritis Res Ther 2019 Apr 15;21(1):94. Epub 2019 Apr 15.

Department of Rheumatology, University of Debrecen Faculty of Medicine, Nagyerdei str 98, Debrecen, 4032, Hungary.

Objectives: Impaired vascular pathophysiology and increased cardiovascular (CV) mortality are associated with rheumatoid arthritis (RA). To date, no genomic analysis of RA- and RA treatment-related vascular pathophysiology has been published. In this pilot study, we performed gene expression profiling in association with vascular pathophysiology in RA patients. Read More

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http://dx.doi.org/10.1186/s13075-019-1862-6DOI Listing

Development of PCR markers specific to Dasypyrum villosum genome based on transcriptome data and their application in breeding Triticum aestivum-D. villosum#4 alien chromosome lines.

BMC Genomics 2019 Apr 15;20(1):289. Epub 2019 Apr 15.

Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, China.

Background: Dasypyrum villosum is an important wild species of wheat (Triticum aestivum L.) and harbors many desirable genes that can be used to improve various traits of wheat. Compared with other D. Read More

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http://dx.doi.org/10.1186/s12864-019-5630-4DOI Listing
April 2019
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Arterial Stiffness, Cognitive Dysfunction, and Adherence to Antihypertensive Agents. Is there a Link to Hypertensive Patients?

Curr Vasc Pharmacol 2019 Apr 15. Epub 2019 Apr 15.

Department of Internal Medicine, Medical School, University of Ioannina, 451 10, Ioannina. Greece.

The incidence of hypertension (HTN) and its cardiovascular (CV) complications are increasing throughout the world. Blood pressure (BP) control remains unsatisfactory worldwide. Medical inertia and poor adherence to treatment are among the factors that can partially explain, why BP control rate remains low. Read More

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http://dx.doi.org/10.2174/1570161117666190415112953DOI Listing

A New Subclade of Identified from .

Int J Mol Sci 2019 Apr 3;20(7). Epub 2019 Apr 3.

Department of Plant Science, University of Manitoba, 66 Dafoe Road, Winnipeg, MB R3T 2N2, Canada.

Blackleg (Phoma stem canker) of crucifers is a globally important disease caused by the ascomycete species complex comprising of and . Six blackleg isolates recovered from cv. Mizspoona in the Willamette Valley of Oregon were characterized as based on standard pathogenicity tests and molecular phylogenetic analysis. Read More

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https://www.mdpi.com/1422-0067/20/7/1668
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http://dx.doi.org/10.3390/ijms20071668DOI Listing
April 2019
1 Read

Sensitive Electrochemical Detection of Caffeic Acid in Wine Based on Fluorine-Doped Graphene Oxide.

Sensors (Basel) 2019 Apr 3;19(7). Epub 2019 Apr 3.

Electrochemical Technology Centre, Department of Chemistry, University of Guelph, 50 Stone Road E, Guelph, ON N1G 2W1, Canada.

We report here a novel electrochemical sensor developed using fluorine-doped graphene oxide (F-GO) for the detection of caffeic acid (CA). The synthesized graphene oxide (GO) and F-GO nanomaterials were systematically characterized with a scanning electron microscope (SEM), and the presence of semi-ionic bonds was confirmed in the F-GO using X-ray photoelectron spectroscopy. The electrochemical behaviours of bare glassy carbon electrode (GCE), F-GO/GCE, and GO/GCE toward the oxidation of CA were studied using cyclic voltammetry (CV), and the results obtained from the CV investigation revealed that F-GO/GCE exhibited the highest electrochemically active surface area and electrocatalytic activity in contrast to the other electrodes. Read More

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http://dx.doi.org/10.3390/s19071604DOI Listing

Aortic Pulse Wave Velocity as a Measure of Cardiovascular Risk in Chronic Obstructive Pulmonary Disease: Two-Year Follow-Up Data from the ARCADE Study.

Medicina (Kaunas) 2019 Apr 2;55(4). Epub 2019 Apr 2.

School of Healthcare Sciences, Heath Park Campus, Cardiff University, Cardiff, UK.

Cardiovascular (CV) disease is a major cause of morbidity and mortality in chronic obstructive pulmonary disease (COPD). Patients with COPD have increased arterial stiffness, which may predict future CV risk. However, the development of arterial stiffness in COPD has not yet been studied prospectively. Read More

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https://www.mdpi.com/1010-660X/55/4/89
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http://dx.doi.org/10.3390/medicina55040089DOI Listing
April 2019
1 Read

Combined targeted Omic and Functional Assays Identify Phospholipases A₂ that Regulate Docking/Priming in Calcium-Triggered Exocytosis.

Cells 2019 Apr 2;8(4). Epub 2019 Apr 2.

Department of Health Sciences, Faculty of Applied Health Sciences and Department of Biological Sciences, Faculty of Mathematics & Science, Brock University, St. Catharines, ON L2S 3A1, Canada.

The fundamental molecular mechanism underlying the membrane merger steps of regulated exocytosis is highly conserved across cell types. Although involvement of Phospholipase A₂ (PLA₂) in regulated exocytosis has long been suggested, its function or that of its metabolites-a lyso-phospholipid and a free fatty acid-remain somewhat speculative. Here, using a combined bioinformatics and top-down discovery proteomics approach, coupled with lipidomic analyses, PLA₂ were found to be associated with release-ready cortical secretory vesicles (CV) that possess the minimal molecular machinery for docking, Ca sensing and membrane fusion. Read More

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http://dx.doi.org/10.3390/cells8040303DOI Listing

High Home Blood Pressure Variability Associates With Exaggerated Blood Pressure Response to Cold Stress.

Am J Hypertens 2019 Apr 15. Epub 2019 Apr 15.

Center for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland.

Background: Exaggerated sympathetic cardiovascular (CV) reactivity to stress associates with elevated risk for clinical and preclinical end points of CV disease. It would be useful to identify these individuals, preferably from feasible measurements commonly used in health care. Our study examined the association between home blood pressure (BP) variability and cardiac workload response to whole-body cold exposure. Read More

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http://dx.doi.org/10.1093/ajh/hpz011DOI Listing

Analytical performance of a single epitope B-type natriuretic peptide sandwich immunoassay on the Minicare platform for point-of-care diagnostics.

Pract Lab Med 2019 May 17;15:e00119. Epub 2019 Mar 17.

Department of Internal Medicine III - Cardiology and Angiology, Medical University of Innsbruck, Innsbruck, Austria.

Point-of-care B-type natriuretic peptide (BNP) testing with adequate analytical performance has the potential to improve patient flow and provide primary care givers with easy-to-use advanced diagnostic tools in the management of heart failure. We present the analytical evaluation of the Minicare BNP immunoassay under development on the Minicare I-20 platform for point-of-care testing. Analytical performance was evaluated using EDTA venous whole blood, EDTA plasma and capillary whole blood. Read More

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http://dx.doi.org/10.1016/j.plabm.2019.e00119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444177PMC

Inter-visit measurement variability of conjunctival vasculature and circulation in habitual contact lens wearers and non-lens wearers.

Eye Vis (Lond) 2019 1;6:10. Epub 2019 Apr 1.

1Miller School of Medicine, Bascom Palmer Eye Institute, University of Miami, 1638 NW 10th Avenue, McKnight Building - Room 202A, Miami, FL 33136 USA.

Background: The inter-visit variation of measuring bulbar conjunctival microvasculature and microcirculation needs to be considered when the results from multiple visits are interpreted. This study examined the inter-visit variability of measuring conjunctival microvasculature and microcirculation in habitual contact lens (HCL) wearers and non-contact lens (NCL) wearers.

Methods: Twenty-eight subjects were recruited including 13 HCL wearers (10 females and 3 males; mean age ± standard deviation, 25. Read More

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http://dx.doi.org/10.1186/s40662-019-0135-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442401PMC

Red wine dryness perception related to physico-chemistry.

J Agric Food Chem 2019 Apr 15. Epub 2019 Apr 15.

The responsibility of condensed tannins in the astringency sensation is well known, even though the physical mechanism is unclear. The study's aims are to go deeper on the relationships between tannin structure and red wine dryness, as well as to evaluate the influence of wine matrix and tannin concentration on the interaction with proteins and dryness perception. Condensed tannins were extracted from two red wines (cv. Read More

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http://pubs.acs.org/doi/10.1021/acs.jafc.9b01480
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http://dx.doi.org/10.1021/acs.jafc.9b01480DOI Listing
April 2019
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The Effect of Acupressure on Cardiac Rhythm and Heart Rate Among Patients With Atrial Fibrillation: The Relationship Between Heart Rate and Fatigue.

Altern Ther Health Med 2019 Jan;25(1):12-19

Objectives: Atrial fibrillation (AF) is the most common arrhythmia among rhythm disturbances causing symptoms such as dyspnea, palpitation, and fatigue. Various methods are used for control and treatment of the disease. This randomized controlled study was conducted to determine the effect of acupressure applied to patients with AF on their cardiac rhythm and heart rate, as well as relationship between heart rate and fatigue. Read More

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January 2019

Development and Reliability of an Athlete Introductory Movement Screen for Use in Emerging Junior Athletes.

Pediatr Exerc Sci 2019 Apr 13:1-10. Epub 2019 Apr 13.

2 Australian Institute of Sport.

Purpose: A novel 4-task Athlete Introductory Movement Screen was developed and tested to provide an appropriate and reliable movement screening tool for youth sport practitioners.

Methods: The overhead squat, lunge, push-up, and a prone brace with shoulder touches were selected based on previous assessments. A total of 28 mixed-sport junior athletes (18 boys and 10 girls; mean age = 15. Read More

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http://dx.doi.org/10.1123/pes.2018-0244DOI Listing

Lower creatinine concentration values and lower inter-laboratory variation among Swedish hospital laboratories in 2014 compared to 1996: results from the Equalis external quality assessment program.

Clin Chem Lab Med 2019 Apr 15. Epub 2019 Apr 15.

External Quality Assessment for Clinical Laboratory Investigations (Equalis), Uppsala, Sweden.

Background Creatinine measurement for estimation of glomerular filtration rate (GFR) is a frequently used laboratory test. Differences in analytic creatinine methods have caused large inter-laboratory variation. International and national standardization efforts have been made in the last decade. Read More

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http://dx.doi.org/10.1515/cclm-2018-0670DOI Listing

Toxicological analysis of cocaine adulterants in blood samples.

Forensic Sci Int 2019 Mar 12;299:95-102. Epub 2019 Mar 12.

National Institute of Legal Medicine and Forensic Sciences, Portugal.

Cocaine was the second most widely used drug in Europe in 2016, with 3.5 million consumers aged 15-64 years old. Adulterants are pharmacologically active substances developed for medical purposes, however, there is little knowledge about their influence in the human body when there is concomitant use with cocaine. Read More

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http://dx.doi.org/10.1016/j.forsciint.2019.03.005DOI Listing

Electrochemical detection of DNA hybridization based on three-dimensional ZnO nanowires/graphite hybrid microfiber structure.

Bioelectrochemistry 2019 Apr 6;128:126-132. Epub 2019 Apr 6.

Institute for Advanced Interdisciplinary Research (iAIR), University of Jinan, Jinan 250022, China. Electronic address:

In the present work, zinc oxide (ZnO) nanowire (NWs)/graphite microfiber hybrid electrodes were used for the detection of DNA hybridization. ZnO NWs were in-situ synthesized onto graphite fibers using the hydrothermal technique, and the result was characterized by X-ray diffraction (XRD), scanning electron microscope (SEM) as well as transmission electron microscope (TEM). An electrochemical sensor for the analysis of DNA hybridization was developed based on immobilizing DNA probes onto the ZnO NWs/graphite microfiber electrodes surface via electrostatic interaction. Read More

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http://dx.doi.org/10.1016/j.bioelechem.2019.04.003DOI Listing
April 2019
4.172 Impact Factor

Mortality after traumatic brain injury in elderly patients: a new scoring system.

World Neurosurg 2019 Apr 11. Epub 2019 Apr 11.

Department of Neurosurgery and Neuro-oncology, Medical University of Lodz, Barlicki University Hospital, Kopcinskiego 22 Street, 90-153 Lodz, Poland. Electronic address:

Traumatic brain injury (TBI) remains a life-threatening condition characterised by growing incidence worldwide, particularly in aging population, in which the primary goal of treatment appears to be avoidance of chronic institutionalization. To identify independent predictors of 30-day mortality or vegetative state in geriatric population and calculate an intuitive scoring system, we screened 480 patients after TBI treated at single department of neurosurgery in 2-year period. We analysed data of 214 consecutive patients aged ≥65 years: demographics, medical history, cause and time of injury, neurological state, radiological reports and laboratory results. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750193105
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http://dx.doi.org/10.1016/j.wneu.2019.04.060DOI Listing
April 2019
2 Reads

Voltammetric determination of nitro compound 4-nitroaniline in aqueous medium at chitosan gelified modified carbon paste electrode (CS@CPE).

Int J Biol Macromol 2019 Apr 11. Epub 2019 Apr 11.

Sultan Moulay Slimane University, Laboratory of Chemistry, Mathematical and Environmental Sciences, Polydisciplinary Faculty, 25 000 Khouribga, Morocco. Electronic address:

A sensitive, selective and reproducible electrochemical method has been established for the electroanalysis of 4-nitroaniline (4-NA) using a carbon paste electrode modified with a chitosan solution gelled in acetic acid (CS@CPE). The modified electrode was then characterized spectroscopically using Fourier Transform Infrared (FTIR) spectroscopy. In addition, the electrochemical and interfacial characteristics of the as-prepared modified electrode were assessed by potentiodynamic cyclic voltammetry (CV) and AC electrochemical impedance spectroscopy (EIS). Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.068DOI Listing

Sodium-glucose co-transporter-2 inhibitors (SGLT2i) use and risk of amputation: an expert panel overview of the evidence.

Metabolism 2019 Apr 10. Epub 2019 Apr 10.

Beth-Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Section of Endocrinology, Boston VA Healthcare System, Harvard Medical School, Boston, MA, USA.

Sodium-glucose co-transporter-2 inhibitors (SGLT2i) are oral antidiabetic agents that exert their glucose-lowering effect by increasing renal excretion of glucose. These drugs have been reported to beneficially affect cardiovascular (CV) and renal outcomes. However, concerns have recently been raised in relation to increased risk of lower-extremities amputation with canagliflozin and it remains unclear whether and to what extent this side effect could also occur with other SGLT2i. Read More

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http://dx.doi.org/10.1016/j.metabol.2019.04.008DOI Listing