51,064 results match your criteria CV Surgery Online[Journal]


Meta-analyses of the effects of Dpp-4 inhibitors, SGLT2 inhibitors and GLP1 receptor analogues on cardiovascular death, myocardial infarction, stroke and hospitalization for heart failure.

Diabetes Res Clin Pract 2019 Feb 19. Epub 2019 Feb 19.

Consultant Endocrinologist. Nightingale Hospital, Kolkata, India.

Aim: To assess the effects DPP- 4i; SGLT2-i & GLP1-RA on CV death, MI, stroke and hHF . This is probably the first meta-analysis to assess the effects of these drugs on MI and stroke in totality, including non-fatal & fatal MI and stroke.

Methods: Scientific databases were searched for RCTs with pre-specified inclusion criteria and each end-point from the selected 13 studies was reported as an effect size (M H odds ratio) with a 95% confidence interval P value. Read More

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http://dx.doi.org/10.1016/j.diabres.2019.02.014DOI Listing
February 2019

Extraction-free whole transcriptome gene expression analysis of FFPE sections and histology-directed subareas of tissue.

PLoS One 2019 22;14(2):e0212031. Epub 2019 Feb 22.

BioSpyder Technologies, Inc., Carlsbad, California, United States of America.

We describe the use of a ligation-based targeted whole transcriptome expression profiling assay, TempO-Seq, to profile formalin-fixed paraffin-embedded (FFPE) tissue, including H&E stained FFPE tissue, by directly lysing tissue scraped from slides without extracting RNA or converting the RNA to cDNA. The correlation of measured gene expression changes in unfixed and fixed samples using blocks prepared from a pellet of a single cell type was R2 = 0.97, demonstrating that no significant artifacts were introduced by fixation. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212031PLOS
February 2019

Prognostic value of the estimated glomerular filtration rate decline in hypertensive patients without chronic kidney disease.

Am J Hypertens 2019 Feb 22. Epub 2019 Feb 22.

CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain.

Background: Our objective of this study was to determine if rate of eGFR decline and its intensity was associated with cardiovascular risk and death in hypertensive patients whose baseline estimated glomerular filtration rate (eGFR) was higher than 60 mL/min/1.73m2.

Methods: This study comprised 2,516 hypertensive patients who had had at least two serum creatinine measurements over a four-year period. Read More

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http://dx.doi.org/10.1093/ajh/hpz029DOI Listing
February 2019

Simultaneous editing of GABA and GSH with Hadamard-encoded MR spectroscopic imaging.

Magn Reson Med 2019 Feb 22. Epub 2019 Feb 22.

Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD.

Purpose: To evaluate the feasibility of simultaneous MR spectroscopic imaging (MRSI) of gamma-aminobutyric acid (GABA) and glutathione (GSH) in the human brain using Hadamard Encoding and Reconstruction of MEGA-Edited Spectroscopy (HERMES).

Methods: Point RESolved Spectroscopy (PRESS)-localized MRSI was performed in GABA and GSH phantoms and in the human brain (n = 3) using HERMES editing and compared to conventional MEGA editing of each metabolite. Multiplet patterns, signal intensities, and metabolite crosstalk were compared between methods. Read More

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http://dx.doi.org/10.1002/mrm.27702DOI Listing
February 2019

Hand, foot and mouth disease associated with coxsackievirus A10: more serious than it seems.

Expert Rev Anti Infect Ther 2019 Feb 22. Epub 2019 Feb 22.

a National Institutes for Food and Drug Control , No. 31 Huatuo Road, Beijing 102629 , China.

Introduction: Hand, foot, and mouth disease (HFMD) is a common viral childhood illness, that has been a severe public health concern worldwide, particularly in the Asia-Pacific region. According to epidemiological data of HFMD during the past decade, the most prevalent causal viruses were enterovirus (EV)-A71, coxsackievirus (CV)-A16, CV-A6 and CV-A10. The public health burden of CV-A10-related diseases has been underestimated as their incidence was lower than that of EV-A71 and CV-A16 in most HFMD outbreaks. Read More

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https://www.tandfonline.com/doi/full/10.1080/14787210.2019.1
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http://dx.doi.org/10.1080/14787210.2019.1585242DOI Listing
February 2019
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Two grapevine metacaspase genes mediate ETI-like cell death in grapevine defence against infection of Plasmopara viticola.

Protoplasma 2019 Feb 22. Epub 2019 Feb 22.

Botanical Institute, Karlsruhe Institute of Technology, Fritz-Haber-Weg 4, 76131, Karlsruhe, Germany.

Metacaspase, as hypersensitive response (HR) executors, has been identified in many plant species. Previously, the entire gene family of metacaspase has been uncovered, but there are still questions that remain unclear regarding HR-regulating gene members. In this study, based on metacaspase expression during different grapevine genotypes interacting with Plasmopara viticola, we identified MC2 and MC5 as candidates involved in HR. Read More

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http://dx.doi.org/10.1007/s00709-019-01353-7DOI Listing
February 2019

In-Bed Pose Estimation: Deep Learning With Shallow Dataset.

IEEE J Transl Eng Health Med 2019 14;7:4900112. Epub 2019 Jan 14.

Augmented Cognition LaboratoryElectrical and Computer Engineering DepartmentNortheastern UniversityBostonMA02115USA.

This paper presents a robust human posture and body parts detection method under a specific application scenario known as in-bed pose estimation. Although the human pose estimation for various computer vision (CV) applications has been studied extensively in the last few decades, the in-bed pose estimation using camera-based vision methods has been ignored by the CV community because it is assumed to be identical to the general purpose pose estimation problems. However, the in-bed pose estimation has its own specialized aspects and comes with specific challenges, including the notable differences in lighting conditions throughout the day and having pose distribution different from the common human surveillance viewpoint. Read More

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http://dx.doi.org/10.1109/JTEHM.2019.2892970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360998PMC
January 2019

Gender-Dependent Alteration of Ca and TNFα Signaling in / Mice, an Obesity-Linked Type 2 Diabetic Model.

Front Physiol 2019 7;10:40. Epub 2019 Feb 7.

INSERM UMR-S 1180, University of Paris-Sud, University of Paris-Saclay, Châtenay-Malabry, France.

Cardiovascular complications are the primary death cause in type 2 diabetes, where inflammation can play a role. We, and others, have previously shown that, in diabetic cardiomyopathy, cardiac dysfunction is associated with Ca mishandling. It is possible that diabetic cardiomyopathy differently affects men and women, as the latter present higher risk to develop heart failure and a higher plasmatic level of the pro-inflammatory cytokine, tumor necrosis factor alpha (TNFα), than men. Read More

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http://dx.doi.org/10.3389/fphys.2019.00040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374335PMC
February 2019

Soluble Graphene Nanosheets for the Sunlight-Induced Photodegradation of the Mixture of Dyes and its Environmental Assessment.

Sci Rep 2019 Feb 21;9(1):2522. Epub 2019 Feb 21.

Department of Chemistry, Malaviya National Institute of Technology, Jaipur, Jaipur, 302017, India.

Currently, the air and water pollutions are presenting the most serious global concerns. Despite the well known tremendous efforts, it could be a promising sustainability if the black carbon (BC) soot can be utilized for the practical and sustainable applications. For this, the almost complete aqueous phase photodegradation of the three well-known organic pollutant dyes as crystal violet (CV); rhodamine B (RhB); methylene blue (MB) and their mixture (CV + RhB + MB), by using water-soluble graphene nanosheets (wsGNS) isolated from the BC soot under the influence of natural sunlight is described. Read More

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http://dx.doi.org/10.1038/s41598-019-38717-1DOI Listing
February 2019

Living alone and cardiovascular disease outcomes.

Heart 2019 Feb 21. Epub 2019 Feb 21.

Peter Munk Cardiac Centre and Women's College Hospital, University of Toronto, Toronto, Ontario, Canada.

Objective: To evaluate cardiovascular (CV) outcomes in outpatients with coronary artery disease (CAD) living alone compared with those living with others.

Methods: The prospeCtive observational LongitudinAl RegIstry oF patients with stable coronarY artery disease (CLARIFY) included outpatients with stable CAD. CLARIFY enrolled participants in 45 countries from November 2009 to July 2010, with 5 years of follow-up. Read More

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http://dx.doi.org/10.1136/heartjnl-2018-313844DOI Listing
February 2019

Precision of Bone Mineral Density Measurements Around Total Ankle Replacement Using Dual Energy X-ray Absorptiometry.

J Clin Densitom 2019 Feb 1. Epub 2019 Feb 1.

IRCCS Istituto Ortopedico Galeazzi, via Riccardo Galeazzi 4, 20161 Milan, Italy; Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, via Carlo Pascal, 36, 20133, Milan, Italy.

Introduction: Joint prosthesis survival is associated with the quality of surrounding bone. Dual-energy X-ray absorptiometry (DXA) is capable to evaluate areal bone mineral density (BMD) around different prosthetic implants, but no studies evaluated periprosthetic bone around total ankle replacement (TAR). Our aim is to determine the precision of the DXA periprosthetic BMD around TAR. Read More

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http://dx.doi.org/10.1016/j.jocd.2019.01.006DOI Listing
February 2019

The hazards and risks of inhaled poorly soluble particles - where do we stand after 30 years of research?

Part Fibre Toxicol 2019 Feb 21;16(1):11. Epub 2019 Feb 21.

Ernest Mario School of Pharmacy, Rutgers University, New Jersey, USA.

Background: In 2006, titanium dioxide and carbon black were classified by IARC as "possibly carcinogenic to humans" and in 2017 the European Chemicals Agency's (ECHA) Committee for Risk Assessment concluded titanium dioxide meets the criteria to be classified as suspected of causing cancer (category 2, through the inhalation route). These classifications were based primarily on the occurrence of lung cancer in rats exposed chronically to high concentrations of these materials, as no such responses have been observed in other animal species similarly exposed. After the EU classification of titanium dioxide, it was suggested that Poorly Soluble particles of Low Toxicity (PSLTs) can be evaluated as a group. Read More

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http://dx.doi.org/10.1186/s12989-019-0294-4DOI Listing
February 2019

Assessment of Cardiovascular Disease Risk and Therapeutic Patterns among Urban Black Rheumatoid Arthritis Patients.

Med Sci (Basel) 2019 Feb 20;7(2). Epub 2019 Feb 20.

Department of Radiology SUNY Downstate Medical Center/Health + Hospitals Kings County, Brooklyn, NY 11201, USA.

Rheumatoid arthritis (RA) patients have nearly twice the risk of cardiovascular disease (CVD) compared to the general population. We aimed to assess, in a predominantly Black population, the prevalence of traditional and RA-specific CVD risk factors and therapeutic patterns. Utilizing ICD codes, we identified 503 RA patients ≥18 years old who were seen from 2010 to 2017. Read More

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http://dx.doi.org/10.3390/medsci7020031DOI Listing
February 2019

Untargeted and Targeted Metabolomics and Tryptophan Decarboxylase In Vivo Characterization Provide Novel Insight on the Development of Kiwifruits ().

Int J Mol Sci 2019 Feb 19;20(4). Epub 2019 Feb 19.

Department of Biotechnology, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.

Kiwifruit ( cv. Hayward) is a commercially important crop with highly nutritional green fleshy fruits. The post-harvest maturation of the fruits is well characterized, but little is known about the metabolic changes that occur during fruit development. Read More

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http://dx.doi.org/10.3390/ijms20040897DOI Listing
February 2019

Elevated 1-h post-load plasma glucose is associated with right ventricular morphofunctional parameters in hypertensive patients.

Endocrine 2019 Feb 21. Epub 2019 Feb 21.

Department of Medical and Surgical Sciences, University Magna Græcia of Catanzaro, Catanzaro, Italy.

Purpose: Emerging data demonstrate that type 2 diabetes mellitus (T2DM) is associated with right ventricular (RV) dysfunction. A cutoff point of 155 mg/dL for the 1-hour (h) post-load plasma glucose, during oral glucose tolerance test (OGTT), identifies patients with normal glucose tolerance (NGT) at high risk to develop T2DM and cardiovascular (CV) disease. We investigated if 1-h post-load glucose may affect RV geometry and function in a group of never-treated hypertensive individuals. Read More

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http://dx.doi.org/10.1007/s12020-019-01873-5DOI Listing
February 2019

Multiplex one-step real-time PCR assay for rapid simultaneous detection of velogenic and mesogenic Newcastle disease virus and H5-subtype avian influenza virus.

Arch Virol 2019 Feb 21. Epub 2019 Feb 21.

Animal Infectious Disease Laboratory, School of Veterinary Medicine, Yangzhou University, 48 East Wenhui Road, Yangzhou, Jiangsu, China.

H5 avian influenza virus (AIV) and velogenic Newcastle disease virus (v-NDV) are pathogens listed in the OIE Terrestrial Animal Health Code and are considered key pathogens to be eliminated in poultry production. Molecular techniques for rapid detection of H5 AIV and v-NDV are required to investigate their transmission characteristics and to guide prevention. Traditional virus isolation, using embryonated chicken eggs, is time-consuming and cannot be used as a rapid diagnostic technology. Read More

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http://dx.doi.org/10.1007/s00705-019-04180-6DOI Listing
February 2019

Visit-to-visit blood pressure variability and hip fracture risk in older persons.

Osteoporos Int 2019 Feb 21. Epub 2019 Feb 21.

Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.

We investigated the association between blood pressure variability measured by the coefficient of variation (CV) of blood pressure and hip fracture in older persons with diabetes. After excluding patients with acute complications and comorbidities, a positive association with similar magnitude of strength was found between BP variability and hip fracture, compared with that in the original analysis.

Introduction: Hypertension is a risk factor of osteoporosis and hip fracture, but studies have yet to investigate whether blood pressure variability measured by the CV of blood pressure can predict hip fracture in older persons with diabetes. Read More

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http://dx.doi.org/10.1007/s00198-019-04899-7DOI Listing
February 2019

A Strategy for Increasing the Efficiency of the Oxygen Reduction Reaction in Mn-Doped Cobalt Ferrites.

J Am Chem Soc 2019 Feb 21. Epub 2019 Feb 21.

Alkaline fuel cells have drawn increasing attention as next-generation energy-conversion devices for electrical vehicles, since high pH enables the use of non-precious metal catalyst. Herein, we report on a family of rationally designed Mn-promoting cobalt ferrite (MCF) spinel nanocrystals, with an optimal composition, Mn0.8(CoFe2)0. Read More

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http://dx.doi.org/10.1021/jacs.8b13296DOI Listing
February 2019

A multiplex fragment ion-based method for accurate proteome quantification.

Anal Chem 2019 Feb 21. Epub 2019 Feb 21.

Multiplex proteome quantification with high accuracy is urgently required to achieve a comprehensive understanding of dynamic cellular and physiological processes. Among the existing quantification strategies, fragment ion-based methods can provide highly accurate results, but the multiplex capacity is limited to 3-plex. Herein, we developed a multiplex pseudo-isobaric dimethyl labeling (m-pIDL) method to extend the capacity of the fragment ion-based method to 6-plex by one-step dimethyl labeling with several millidalton and dalton mass differences between precursor ions and enlarging the isolation window of precursor ions to 10 m/z during data acquisition. Read More

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http://dx.doi.org/10.1021/acs.analchem.8b04806DOI Listing
February 2019

Hyperlipoprotein(a) in patients with spondyloarthritis: results of the Cardiovascular in Rheumatology (CARMA) project.

Clin Exp Rheumatol 2019 Feb 15. Epub 2019 Feb 15.

Epidemiology, Genetics & Atherosclerosis Res. Group on Systemic Inflammatory Diseases, Rheumatology Div., Hosp. Univ. Marqués de Valdecilla, IDIVAL, Univ. of Cantabria, Santander, Spain, and Univ. of the Witwatersrand, Johannesburg, South Africa.

Objectives: Cardiovascular (CV) disease is one of the main causes of morbi-mortality in spondyloarthritis (SpA), partially explained by traditional CV risk factors. Information on lipoprotein(a) [Lp(a)], a non-conventional risk factor, in SpA is scarce. In this study we assessed the prevalence of hyperlipoproteinaemia(a) in SpA patients and analysed the possible related factors. Read More

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February 2019

Inter-day test-retest reliability and feasibility of isokinetic, isometric, and isotonic measurements to assess quadriceps endurance in people with chronic obstructive pulmonary disease: A multicenter study.

Chron Respir Dis 2019 Jan-Dec;16:1479973118816497

1 Department of Community Medicine and Rehabilitation, Unit of Physiotherapy, Umeå University, Umeå, Sweden.

The aims were to determine reliability and feasibility of measurements to assess quadriceps endurance in people with chronic obstructive pulmonary disease. Sixty participants (forced expiratory volume in one second (mean ± standard deviation) 55 ± 18% of predicted, age 67 ± 8 years) were tested in an inter-day, test-retest design. Isokinetic, isometric, and isotonic protocols were performed using a computerized dynamometer. Read More

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http://dx.doi.org/10.1177/1479973118816497DOI Listing
February 2019

Aqueous extracts of Syzygium brazzavillense can inhibit the infection with coxsackievirus B4 in vitro.

J Med Virol 2019 Feb 20. Epub 2019 Feb 20.

Univ. Lille, Faculté de Médecine, CHU Lille, Laboratoire de Virologie EA3610, Lille, France.

Traditional practitioners commonly use plant crude extracts to treat various diseases in patients with symptoms that can be seen during enterovirus infections. In this study, the anti-enteroviral activity of medicinal plants from Republic of Congo has been evaluated in vitro. Through an ethnopharmacological approach, seven plants grouped into 6 families were identified. Read More

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http://dx.doi.org/10.1002/jmv.25436DOI Listing
February 2019

Comparative sequence and methylation analysis of chloroplast and amyloplast genomes from rice.

Plant Mol Biol 2019 Feb 20. Epub 2019 Feb 20.

School of Science, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Bandar Sunway, Selangor Darul Ehsan, Malaysia.

Key Message: Grain amyloplast and leaf chloroplast DNA sequences are identical in rice plants but are differentially methylated. The leaf chloroplast DNA becomes more methylated as the rice plant ages. Rice is an important crop worldwide. Read More

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http://dx.doi.org/10.1007/s11103-019-00841-xDOI Listing
February 2019

New Therapeutic Strategies for Type 2 Diabetes .

Methodist Debakey Cardiovasc J 2018 Oct-Dec;14(4):281-288

HOUSTON METHODIST HOSPITAL, HOUSTON, TEXAS.

Pharmacological options for treatment of type 2 diabetes (T2D) have advanced rapidly during the last 10 years, allowing clinicians to target different pathophysiological defects in this disease. There are currently 12 different classes of drugs available to treat T2D. The most exciting development is the demonstration of cardiovascular (CV) benefits from two of these new classes, the glucagon-like peptide-1 receptor agonists (GLP-1 RA) and selective sodium glucose transporter 2 (SGLT2) inhibitors. Read More

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http://dx.doi.org/10.14797/mdcj-14-4-281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369623PMC
February 2019

Update on Management of Type 2 Diabetes for Cardiologists.

Methodist Debakey Cardiovasc J 2018 Oct-Dec;14(4):273-280

HOUSTON METHODIST HOSPITAL, HOUSTON, TEXAS.

The management of type 2 diabetes mellitus has evolved over the last several years as new antidiabetic agents continue to arrive and change the goals of diabetes care. In 2008, the U.S. Read More

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http://dx.doi.org/10.14797/mdcj-14-4-273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369620PMC
February 2019

Trans-Graft Protection Against Pierce's Disease Mediated by Transgenic Grapevine Rootstocks.

Front Plant Sci 2019 6;10:84. Epub 2019 Feb 6.

Department of Plant Sciences, University of California, Davis, Davis, CA, United States.

A field study showed that transgenic grapevine rootstocks can provide trans-graft-mediated protection to a wild type scion against Pierce's disease (PD) development. We individually field-tested two distinct strategies. The first expressed a chimeric antimicrobial protein (CAP) that targeted the functionality of the lipopolysaccharide (LPS) surface of (), the causative agent of PD. Read More

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http://dx.doi.org/10.3389/fpls.2019.00084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372540PMC
February 2019

Sex differences in the H NMR metabolic profile of serum in cardiovascular risk patients.

Sci Rep 2019 Feb 20;9(1):2380. Epub 2019 Feb 20.

Cardiovascular Diseases Research Group, Department of Cardiology, Vall d'Hebron University Hospital and Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain.

Personalized diagnosis and risk stratification of cardiovascular diseases would allow optimizing therapeutic strategies and lifestyle changes. Metabolomics is a promising technique for personalized diagnosis and prognosis; however, various physiological parameters, including sex, influence the metabolic profile thus hampering its translation to the clinic. Knowledge of the variation in the metabolic profile associated with sex would facilitate metabolomic translation to the clinic. Read More

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http://dx.doi.org/10.1038/s41598-019-38881-4DOI Listing
February 2019

Estimation of Gadolinium-based Contrast Agent Concentration Using Quantitative Synthetic MRI and Its Application to Brain Metastases: A Feasibility Study.

Magn Reson Med Sci 2019 Feb 19. Epub 2019 Feb 19.

Department of Radiology, Juntendo University School of Medicine.

Purpose: Gadolinium-based contrast agents (GBCA) provide valuable information for assessing and differentiating lesions in the body. However, contrast enhancement evaluation on conventional MRI is qualitative because the signal intensity uses an arbitrary scale. An approach that allows more quantitative assessment of tissue enhancement that can be integrated into clinical use is desirable. Read More

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http://dx.doi.org/10.2463/mrms.mp.2018-0119DOI Listing
February 2019

[Consideration on SNR in Synthetic MRI].

Nihon Hoshasen Gijutsu Gakkai Zasshi 2019 ;75(2):160-166

Department of Radiological Sciences, Faculty of Health Sciences, Komazawa University.

Synthetic magnetic resonance imaging (MRI) can create different contrast weighted images by quantifying the T, T, and proton density values of the subjects from a single series of scan data. It has not been clarified how the signal to noise ratio (SNR) of the synthesized image varies depending on imaging parameters. We investigated the change of SNR in synthesized MR images by the experiment using self-made phantom. Read More

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http://dx.doi.org/10.6009/jjrt.2019_JSRT_75.2.160DOI Listing
January 2019

Impact of cultivated hosts on the recombination of .

J Virol 2019 Feb 20. Epub 2019 Feb 20.

Department of Plant Pathology and Environmental Microbiology, Center for Infectious Disease Dynamics, Pennsylvania State University, University Park, PA, United States of America.

(CMV) is one of the most successful viruses known, infecting over 1,200 species of plants. Like other single-stranded RNA viruses, CMV is known to have a high potential for population diversity due to error-prone replication and short generation times. Recombination also is a mechanism allowing viruses to adapt to new hosts. Read More

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http://jvi.asm.org/lookup/doi/10.1128/JVI.01770-18
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http://dx.doi.org/10.1128/JVI.01770-18DOI Listing
February 2019
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Siblings of patients with rheumatoid arthritis are at increased risk of acute coronary syndrome.

Ann Rheum Dis 2019 Feb 20. Epub 2019 Feb 20.

Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.

Objectives: To investigate a potential shared susceptibility between rheumatoid arthritis (RA) and acute coronary syndrome (ACS) by estimation of the risk of ACS among full siblings of patients with RA.

Methods: By linking nation-wide Swedish registers, we identified a cohort of patients with new-onset RA 1996-2016, age- and sex-matched (5:1) general population comparator subjects, full siblings of RA and comparator subjects, and incident ACS events through 31 December 2016. We used Cox regression to estimate the HR of ACS among patients with RA and the siblings of patients with RA versus the general population, overall and stratified by RA serostatus. Read More

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http://dx.doi.org/10.1136/annrheumdis-2018-214828DOI Listing
February 2019

Fixed-ratio combination of insulin degludec and liraglutide (IDegLira) improves cardiovascular risk markers in patients with type 2 diabetes uncontrolled on basal insulin.

Diabetes Obes Metab 2019 Feb 20. Epub 2019 Feb 20.

Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.

This post hoc analysis investigated effects of insulin degludec/liraglutide fixed-ratio combination (IDegLira) versus comparators on cardiovascular (CV) risk markers from DUAL II (versus insulin degludec), DUAL V (versus insulin glargine 100 units/mL) and DUAL VII (versus basal-bolus therapy) in patients grouped by sex, age (<65 years, ≥65 years) and diabetes duration (<10 years, ≥10 years). Treatment contrasts were in favour of IDegLira in many subgroups for changes from baseline in HbA1c (DUAL II, DUAL V), body weight (all three trials), systolic blood pressure (BP; all three trials), high-density lipoprotein cholesterol (DUAL VII) and low-density lipoprotein cholesterol (LDL-C; DUAL II, DUAL V). Higher heart rates were seen with IDegLira versus comparators (all three trials) plus significantly higher diastolic BP in males (DUAL V). Read More

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http://dx.doi.org/10.1111/dom.13675DOI Listing
February 2019

Upregulation of MMP-9 and CaMKII prompts cardiac electrophysiological changes that predispose denervated transplanted hearts to arrhythmogenesis after prolonged cold ischemic storage.

Biomed Pharmacother 2019 Feb 20;112:108641. Epub 2019 Feb 20.

Department of Anaesthesiology, Guizhou Medical University, Guiyang, China.

Background: Although the importance of the potential mechanisms of arrhythmogenesis, including cardiac electrophysiology dysfunction and gap junction electrical uncoupling by Cx43 degradation under pathological conditions, has been widely and thoroughly established, the correlations between these mechanisms and biomarkers of cold ischemic insult have not yet been confirmed. Limited evidence suggests that these biomarkers are significantly associated with cardiac dysrhythmia. Thus, in this study, we analyzed such correlations in denervated transplanted hearts. Read More

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http://dx.doi.org/10.1016/j.biopha.2019.108641DOI Listing
February 2019

Multifunctional magnetic sphere-MoS@Au hybrid for surface-enhanced Raman scattering detection and visible light photo-Fenton degradation of aromatic dyes.

Chemosphere 2019 Feb 14;223:465-473. Epub 2019 Feb 14.

College of Chemistry and Chemical Engineering, Jiangxi Normal University, China. Electronic address:

A ternary hybrid, MNPs-MoS@Au, composed of gold nanoparticles (AuNPs) grown on a magnetic sphere (MNPs)-MoS microflower composite (MNPs-MoS) was proposed for surface-enhanced Raman scattering (SERS) detection and visible-light photo-Fenton degradation of aromatic dyes. The hybrid was prepared by sequential solvothermal growth of MNPs and MoS, and electroless deposition of AuNPs. A comparison of results revealed that the synergy among these components endowed the hybrid with a much higher SERS enhancement ability than MNPs, or MNPs@MoS. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2019.02.073DOI Listing
February 2019

Editor-in-Chief's Top Picks From 2018.

Authors:
Valentin Fuster

J Am Coll Cardiol 2019 Feb;73(7):826-867

Each week, I record audio summaries for every article in JACC, as well as an issue summary. Although this process is quite time-consuming, I have become familiar with every paper that we publish. Thus, I have personally selected the top 100 papers (both Original Investigations and Review Articles) from 15 distinct specialties each year. Read More

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http://dx.doi.org/10.1016/j.jacc.2019.01.004DOI Listing
February 2019
1 Read

Bi-exponential modeling derives novel parameters for the critical speed concept.

Physiol Rep 2019 Feb;7(4):e13993

Rocky Mountain University of Health Professions, Provo, Utah.

All-out exercise testing (AOT) has emerged as a method for quantifying critical speed (CS) and the curvature constant (D'). The AOT method was recently validated for shuttle running yet how that method compares with linear running is unknown. In the present study, we utilized a novel bi-exponential model that derives CS and D' with additional new parameters from the AOT method. Read More

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http://dx.doi.org/10.14814/phy2.13993DOI Listing
February 2019

Assessing the impact of certain exercises on the spatial head posture.

Int J Occup Med Environ Health 2019 Feb 5. Epub 2019 Feb 5.

Bronislaw Czech Physical Academy Education, Cracow, Poland (Orthopedic Rehabilitation Institute, Clinical Rehabilitation Division, Motor Rehabilitation Department).

Objectives: The head constitutes 6% of the total body weight, which is linked to the cervical spine and all other joints through the kinematic chain by various muscles. The forward head posture is one of the most common postural disorders and seems to be especially dangerous. The goal of the work was to assess the impact of 4 weeks of training neck and nape muscles on the head posture. Read More

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http://www.journalssystem.com/ijomeh/Assessing-the-impact-of
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http://dx.doi.org/10.13075/ijomeh.1896.01293DOI Listing
February 2019
1 Read

Efficacy of a standardised acupuncture approach for women with bothersome menopausal symptoms: a pragmatic randomised study in primary care (the ACOM study).

BMJ Open 2019 Feb 19;9(1):e023637. Epub 2019 Feb 19.

The Research Unit for General Practice, Department of Public Health, University of Southern Denmark, Odense, Denmark.

Objective: To investigate the efficacy of a standardised brief acupuncture approach for women with moderate-to-severe menopausal symptoms.

Design: Randomised and controlled, with 1:1 allocation to the intervention group or the control group. The assessor and the statistician were blinded. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-023637DOI Listing
February 2019

First Report of Alfalfa mosaic virus on Rhamnus alaternus in France.

Authors:
L Cardin B Moury

Plant Dis 2006 Aug;90(8):1115

INRA, Station de Pathologie Végétale, Domaine St Maurice, BP94, F-84143 Montfavet cedex, France.

Rhamnus alaternus L. (evergreen buckthorn), family Rhamnaceae, is a small, hardy shrub from Mediterranean regions grown for its ornamental persistent green or variegated foliage. Chlorotic oak leaf or ringspot symptoms on R. Read More

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http://dx.doi.org/10.1094/PD-90-1115CDOI Listing

First Report of Southern Blight Incited by Sclerotium rolfsii on Potato (Solanum tuberosum) in Northern Italy.

Plant Dis 2006 Aug;90(8):1114

Centre of Competence for the Innovation in the Agro-Environmental Sector (AGROINNOVA), Via Leonardo da Vinci 44, 10095 Grugliasco, Italy.

During the summer of 2005, plants of potato (Solanum tuberosum L.) showing severe basal rot symptoms were observed in a commercial field near Alessandria (northern Italy). The first symptoms were detected during early July in correspondence with a strong increase of air temperature (as much as 38°C, with an average monthly increase of 10°C) and relative humidity. Read More

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http://dx.doi.org/10.1094/PD-90-1114CDOI Listing

First Report of Crown Rot of Gazania rigens Caused by Sclerotinia sclerotiorum in Louisiana.

Authors:
G E Holcomb

Plant Dis 2006 Aug;90(8):1114

Department of Plant Pathology and Crop Physiology, Louisiana State University AgCenter, Baton Rouge 70803.

Gazania rigens (L.) (treasure flower, Asteraceae) is grown as a winter and summer annual bedding plant in Louisiana and the lower southern United States. In March 2006, cv. Read More

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http://dx.doi.org/10.1094/PD-90-1114ADOI Listing

First Report of Leaf Spot Caused by Phoma exigua on Hydrangea macrophylla in Italy.

Plant Dis 2006 Aug;90(8):1113

Centre of Competence AGROINNOVA, University of Torino, Via Leonardo da Vinci 44, 10095 Grugliasco, Italy.

Hydrangea macrophylla is grown in Italy as a potted plant and also for landscaping. During the fall of 2005 in a nursery located in Lazio (central Italy), a severe foliar disease was observed on 12-month-old potted plants of cv. Hanabi. Read More

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http://dx.doi.org/10.1094/PD-90-1113BDOI Listing

First Report of Broomrape (Orobanche crenata) Infecting Lettuce in Southern Spain.

Plant Dis 2006 Aug;90(8):1112

CAF-UCO and IAS-CSIC, P.O. Box 3048, 14080 Córdoba, Spain.

Broomrapes (Orobanche spp., Orobanchaceae) are chlorophyll-lacking, obligately parasitic flowering plants that infect roots of many dicotyledoneous species and cause severe damage to vegetable and field crops worldwide, but particularly in North Africa, southern and eastern Europe, and the Middle East. (1). Read More

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http://dx.doi.org/10.1094/PD-90-1112BDOI Listing

First Report of Acidovorax avenae subsp. citrulli Infecting Edible Seed Watermelon (Citrullus lanatus var. lanatus) in China.

Plant Dis 2006 Aug;90(8):1112

Department of Plant Pathology, College of Agronomy and Biotechnology, CAU, Beijing 100094, PR China.

Edible seed watermelon, Citrullus lanatus var. lanatus, is a type of watermelon from which only the seeds are consumed. Between 2003 and 2005, a bacterial disease was discovered on this type of watermelon in several regions of Xinjiang Province in western China, with a diseased area of 40,000 ha. Read More

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http://dx.doi.org/10.1094/PD-90-1112ADOI Listing

First Report of Downy Mildew on Greenhouse and Landscape Coleus Caused by a Peronospora sp. in Louisiana and New York.

Plant Dis 2006 Aug;90(8):1111

School of Engineering of Lullier, University of Applied Sciences of Western Switzerland, 1254 Jussy, Switzerland.

In May 2005, two commercial greenhouse flower growers, one in Louisiana (LA) and one in New York (NY), submitted coleus, Solenostemon scutellarioides (L.) Codd, plants for diagnosis after observing stunted growth, inward curling and twisting of leaves, and leaf abscission on multiple cultivars. Downy mildew-like growth was observable with hand lens or a microscope on the abaxial leaf surfaces of affected plants. Read More

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http://dx.doi.org/10.1094/PD-90-1111BDOI Listing

Occurrence of Phytophthora Blight on Pumpkin in New Mexico.

Authors:
S Sanogo M Clary

Plant Dis 2006 Aug;90(8):1110

Clary Ag Services, Deming, NM 88031.

During 2004 and 2005, two fields in Luna County and one field in Doña Ana County in southern New Mexico displayed pumpkin (Cucurbita pepo cv. Magic Lantern) plants with necrotic spots on leaves and dark brown and water-soaked lesions on petioles, vines, and fruits. Lesions on several fruits were covered with white mycelial mats that were also visible in the lumen when fruits were sectioned. Read More

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http://apsjournals.apsnet.org/doi/10.1094/PD-90-1110A
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http://dx.doi.org/10.1094/PD-90-1110ADOI Listing
August 2006
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First Report of Rhizoctonia solani AG 4 on Lamb's Lettuce in Italy.

Plant Dis 2006 Aug;90(8):1109

Center of Competence AGROINNOVA, University of Torino, Via Leonardo da Vinci, 44, 10095 Grugliasco, Italy.

Lamb's lettuce or corn salad (Valerianella olitoria) is increasingly grown in Italy and used primarily in the preparation of mixed processed salad. In the fall of 2005, plants of lamb's lettuce, cv Trophy, exhibiting a basal rot were observed in some commercial greenhouses near Bergamo in northern Italy. The crown of diseased plants showed extensive necrosis, progressing to the basal leaves, with plants eventually dying. Read More

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http://dx.doi.org/10.1094/PD-90-1109CDOI Listing

New Polish Isolate of Pepino mosaic virus Highly Distinct from European Tomato, Peruvian, and US2 Strains.

Plant Dis 2006 Aug;90(8):1106

Institute of Plant Protection, 60-318 Poznań, Poland.

Pepino mosaic virus (PepMV, genus Potexvirus) was first described on pepino (Solanum muricatum) in Peru during 1980. Since 1999, the virus was reported in several European countries and in North and South America as an agent of viral disease of tomato crops. In Poland in 2002, the PepMV-SW isolate that was genetically similar to European isolates (approximately 99% identity) was identified (3). Read More

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http://dx.doi.org/10.1094/PD-90-1106CDOI Listing

First Report of "Candidatus Phytoplasma asteris"-Related Strains in Brassica rapa in Saskatchewan, Canada.

Plant Dis 2006 Jun;90(6):832

AAFC-ECORC, Ottawa, ON, K1A OC6 Canada.

"Candidatus phytoplasma asteris" and related strains (i.e., aster yellows group 16SrI) have been associated with diseases of numerous plant species worldwide. Read More

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http://dx.doi.org/10.1094/PD-90-0832CDOI Listing