49,336 results match your criteria CV Surgery Online[Journal]


Mass spectrometry imaging of low molecular weight metabolites in strawberry fruit (Fragaria x ananassa Duch.) cv. Primoris with Ag nanoparticle enhanced target.

Phytochemistry 2018 Dec 11;159:11-19. Epub 2018 Dec 11.

Rzeszów University of Technology, Faculty of Chemistry, 6 Powstańców Warszawy Ave., 35-959, Rzeszów, Poland.

Strawberry (Fragaria x ananassa Duch., Rosaceae) is the subject of many research studies due to its numerous features such as unique taste, aroma and health qualities. The distribution of low molecular weight metabolites belonging to aldehydes, ketones, alcohols, esters, organic acids, phenolics, amino acids and sugars classes within strawberry fruit cross-section was studied using mass spectrometry imaging (MSI) method with Ag nanoparticle enhanced target (AgNPET). Read More

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December 2018

Highly Efficient Production of Chiral Amines in Batch and Continuous Flow by Immobilized ω-Transaminases on Controlled Porosity Glass Metal-Ion Affinity Carrier.

J Biotechnol 2018 Dec 11. Epub 2018 Dec 11.

Van' t Hoff Institute for Molecular Sciences, HIMS-Biocat & HetCat, University of Amsterdam, Science Park 904, 1098 XH, The Netherlands. Electronic address:

In this study, two stereocomplementary ω-transaminases from Arthrobacter sp. (AsR-ωTA) and Chromobacterium violaceum (Cv-ωTA) were immobilized via iron cation affinity binding onto polymer-coated controlled porosity glass beads (EziG). The immobilization procedure was studied with different types of carrier materials and immobilization buffers of varying compositions, concentrations, pHs and cofactor (PLP) concentrations. Read More

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December 2018

Clinical and aetiological study of hand, foot and mouth disease in southern Vietnam, 2013-2015: inpatients and outpatients.

Int J Infect Dis 2018 Dec 11. Epub 2018 Dec 11.

Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Background: Hand, foot and mouth disease (HFMD) has been associated with large outbreaks among young children, including severe illness and fatality, in the Asia-Pacific Region since 1997. Severe illness is often associated with enterovirus A71 (EV-A71). Vietnam experienced a large sustained outbreak of 200. Read More

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December 2018

Optimal medical therapy vs. coronary revascularization for patients presenting with chronic total occlusion: A meta-analysis of randomized controlled trials and propensity score adjusted studies.

Catheter Cardiovasc Interv 2018 Dec 13. Epub 2018 Dec 13.

Department of Cardiology and Angiology II, University Heart Center Freiburg, Bad Krozingen, Germany.

Introduction: The optimal management of patients with coronary chronic total occlusions (CTO) remains controversial. This meta-analysis aims to compare percutaneous coronary intervention of CTO (CTO-PCI) versus optimal medical therapy (OMT) in CTO patients.

Methods: A literature search with highly specific terms was conducted using MEDLINE, EMBASE, and Web of Science to identify most relevant randomized controlled trials (RCTs) and observational studies with propensity score matching (PSM) evaluating differences in between CTO-PCI versus OMT. Read More

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December 2018
1 Read

Neural circuitry of a polycystin-mediated hydrodynamic startle response for predator avoidance.

Elife 2018 Dec 14;7. Epub 2018 Dec 14.

Living Systems Institute, University of Exeter, Exeter, United Kingdom.

Startle responses triggered by aversive stimuli including predators are widespread across animals. These coordinated whole-body actions require the rapid and simultaneous activation of a large number of muscles. Here we study a startle response in a planktonic larva to understand the whole-body circuit implementation of the behaviour. Read More

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December 2018

Assessment of System Accuracy, Intermediate Measurement Precision, and Measurement Repeatability of a Blood Glucose Monitoring System Based on ISO 15197.

J Diabetes Sci Technol 2018 Dec 14:1932296818821105. Epub 2018 Dec 14.

1 Institut für Diabetes-Technologie, Forschungs- und Entwicklungsgesellschaft mbH an der Universität Ulm, Ulm, Germany.

Background:: Analytical quality of blood glucose monitoring systems (BGMS) is an important aspect for many diabetes patients. Sufficiently high analytical quality is required for adequate diabetes therapy.

Methods:: In this study, system accuracy and measurement precision of a BGMS were assessed based on ISO 15197:2013. Read More

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December 2018

Levels of Polychlorinated Biphenyls in Plastic Resin Pellets from Six Beaches on the Accra-Tema Coastline, Ghana.

J Health Pollut 2016 Sep 13;6(11):9-17. Epub 2016 Sep 13.

School of Basic and Biomedical Sciences, University of Health and Allied Sciences, PMB 31 Ho, Volta Region, Ghana.

Background: Polychlorinated biphenyls (PCBs) are organic compounds, known to be carcinogenic and banned by the Stockholm Convention. PCBs are hydrophobic substances able to accumulate in organic materials, including plastic pellets. Plastic resin pellets are industrial raw materials that are remolded finished products for industrial and domestic use, commonly used for packaging. Read More

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September 2016

The development of simultaneous measurement of viral load and physical status for human papillomavirus 16 and 18 co-infection using multiplex quantitative polymerase chain reaction.

Oncol Lett 2018 Dec 4;16(6):6977-6987. Epub 2018 Oct 4.

Center for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.

Persistent infection with human papillomavirus (HPV) type 16 and 18 is known to be a major risk factor for cervical cancer. Increased prevalence of co-infection with these high-risk types has been observed in pre-cancerous and cancerous tissues. The determination of physical status and copy numbers of viruses is therefore useful in clinical settings. Read More

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December 2018

Diabetic and Elder Patients Experience Superior Cardiovascular Benefits After Gastric Bypass Induced Weight Loss.

Front Endocrinol (Lausanne) 2018 28;9:718. Epub 2018 Nov 28.

Endocrine, Cardiovascular and Metabolic Research, Unit for Multidisciplinary Research in Biomedicine, University of Porto, Porto, Portugal.

Obesity and obesity related co-morbidities are well-recognized risks for cardiovascular (CV) disease and mortality. Weight loss improves CV risk factors and the efficacy of bariatric surgery in decreasing CV mortality is now well-established. Our aim was to assess CV risk progression and occurrence of CV events in a cohort of patients that underwent Roux-en-Y gastric bypass (RYGB) for obesity treatment in a single academic public center. Read More

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November 2018

Changes in fruit firmness, cell wall composition and transcriptional profile in the yellow fruited tomato 1 (yft1) mutant.

J Agric Food Chem 2018 Dec 13. Epub 2018 Dec 13.

Fruit firmness is an important trait in tomato (Solanum lycopersicum), associated with shelf life and economic value; however, the precise mechanism determining fruit softening remains elusive. A yellow fruit tomato 1(yft1) mutant, harbors a genetic lesion in the YFT1 gene, and has significantly firmer fruit than those of the cv. M82 wild type at a red ripe stage, 54 dpa (days post anthesis). Read More

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December 2018

The impact of abdominal fat on abdominal aorta calcification measured on non-enhanced CT.

Medicine (Baltimore) 2018 Dec;97(49):e13233

Department of Radiology, Hillel Yaffe Medical Center, Hadera, Affiliated with the Faculty of Medicine, Technion- Israel Institute of Technology, Haifa, Israel.

Cardiovascular (CV) morbidity, atherosclerosis, and obesity are all targets of clinical concern and vast research, as is the association between them. Aim of this study is to assess the impact of adipose tissue (including visceral and subcutaneous fat) on abdominal aorta calcification measured on non-enhanced computed tomography (CT). We retrospectively included 492 patients who underwent non-enhanced CT scans during workup for clinically suspected renal colic. Read More

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December 2018
1 Read

Population based hospitalization burden of laboratory-confirmed hand, foot and mouth disease caused by multiple enterovirus serotypes in Southern China.

PLoS One 2018 13;13(12):e0203792. Epub 2018 Dec 13.

Division of Infectious Disease, Key Laboratory of Surveillance and Early-warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, China.

Background: Hand, foot and mouth disease (HFMD) is spread widely across Asia, and the hospitalization burden is currently not well understood. Here, we estimated serotype-specific and age-specific hospitalization rates of HFMD in Southern China.

Methods: We enrolled pediatric HFMD patients admitted to 3/3 county-level hospitals, and 3/23 township-level hospitals in Anhua county, Hunan (CN). Read More

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December 2018
1 Read

Determination of acceptable limits of precision parameters for lymphocyte count by flow cytometry.

Ann Biol Clin (Paris) 2018 Dec;76(6):687-693

Laboratoire d'immunologie, CHU de Nice, France.

Performance of lymphocyte count by flow cytometry is difficult to evaluate because of the lack of desirable range for precision performance. The aim of this work was to propose recommendations for acceptable precision variability. Data of repeatability and reproducibility of two levels of IQC were collected from sixty-four laboratories. Read More

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December 2018

An Artificial Sandwich Base for Monitoring Single Nucleobase Changes and Charge Transfer Rates in DNA.

Anal Chem 2018 Dec 13. Epub 2018 Dec 13.

Developing a convenient method able to discriminate among different types of DNA nucleotides within a target sequence of the human genome is extremely challenging. We herein report an artificial ferrocene-base (Fe-base) that was synthesized and incorporated into different loci of a DNA strand. The Fe-base replacement on a nucleobase can interact with DNA bases and efficiently discriminate among A, T, G, C DNA bases of the complementary locus based on interacting electrochemical properties. Read More

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December 2018

Development of Virus Resistance Transgenic Cotton Using Cotton Leaf Curl Virus Antisense ßC1 Gene.

Authors:
S S Sohrab

Methods Mol Biol 2019 ;1902:293-305

Special Infectious Agents Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.

Cotton (Gossypium hirsutum L.) is the most economically important crop in the world and produced 90% of the total natural cellulose fiber which is utilized to make cotton fabrics. The production of cotton is affected by many several diseases, and among them, viral disease, especially leaf curl, is the most destructive disease caused by a begomovirus transmitted by whiteflies vector. Read More

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January 2019

Development of Insect-Resistant Transgenic Cotton with Chimeric TVip3A* Accumulating in Chloroplasts.

Methods Mol Biol 2019 ;1902:281-292

Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.

An optimized vip3A gene, designated as vip3A*, was chemically synthesized, and a chloroplast transit peptide sequence of thi1 gene was attached to its 5' end to produce the tvip3A*. vip3A* and tvip3A* genes were transformed into Gossypium hirsutum cv. Zhongmiansuo35 mediated by Agrobacterium tumefaciens. Read More

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January 2019

Anti-müllerian Hormone During Natural Cycle Presents Significant Intra and Intercycle Variations When Measured With Fully Automated Assay.

Front Endocrinol (Lausanne) 2018 27;9:686. Epub 2018 Nov 27.

IVF department, IVIRMA Middle-East Fertility Clinic, Abu Dhabi, United Arab Emirates.

Anti-Müllerian hormone (AMH) is an important ovarian reserve marker for baseline assessment and therapeutic strategy in fertility treatments, which is considered reliable when measured on any day of the cycle. Recent data have pointed toward significant fluctuations of AMH and questioned whether a single measurement is reliable for clinical decision-making. The aim of this study was to evaluate whether the AMH does have significant variations during a natural cycle when a fully automated assay is used for the sample analysis. Read More

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November 2018

Acceptable "Real-Life" Variability for Lymphocyte Counts by Flow Cytometry.

Cytometry B Clin Cytom 2018 Dec 7. Epub 2018 Dec 7.

Immunology Laboratory FRE-CNRS 3312, University Hospital, Cedex, France.

Background: As part of quality assurance in laboratories (labs) offering clinical cell analysis by flow cytometry (FCM), cell counting precision and robustness are evaluated but international desirable ranges are still missing. The aim of this study was to provide desirable interlaboratory variability reference values.

Methods: A prospective survey on monthly quality assessment was proposed to all French laboratories routinely performing lymphocyte subpopulation quantification, over one arbitrarily selected month (June 2017), regardless of instrument, counting system and quality controls used. Read More

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December 2018

The impact of apelin and relaxin plasma levels in masked hypertension and white coat hypertension.

J Clin Hypertens (Greenwich) 2018 Dec 7. Epub 2018 Dec 7.

Hypertension Excellence Centre - ESH, Department of Cardiology, LAIKO General Hospital, Athens, Greece.

Masked hypertension (HTN) and white coat hypertension represent two reverse forms of clinical HTN with questionable prognostic significance. Recent evidence supports that low apelin and relaxin plasma levels contribute to vascular damage accelerating atherogenesis and predisposing to HTN and cardiovascular (CV) events. The aim of this study was to compare apelin and relaxin plasma levels between patients with masked hypertension (MH) and those with white coat HTN (WCH). Read More

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December 2018

Validity and reliability of a freehand 3D ultrasound system for the determination of triceps surae muscle volume in children with cerebral palsy.

J Anat 2018 Dec 7. Epub 2018 Dec 7.

School of Occupational Therapy, Social Work and Speech Pathology, Faculty of Health Sciences, Curtin University, Perth, WA, Australia.

This study assessed the validity, intra-rater and inter-rater reliability of segmentation of in vivo medial gastrocnemius (MG), lateral gastrocnemius (LG) and soleus (SOL) muscle volume measurement using a single sweep freehand 3D ultrasound (3DUS) in children with cerebral palsy (CP). The MG, LG and SOL of both limbs of 18 children with CP (age 8 years 4 months ± 1 year 10 months, 11 males, unilateral CP = 9, bilateral CP = 9, Gross Motor Functional Classification System I = 11, II = 7) were scanned using freehand 3DUS and magnetic resonance imaging (MRI). All freehand 3DUS and MRI images were segmented and volumes rendered by two raters. Read More

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December 2018

Arterial Stiffness in Balkan Endemic Nephropathy, an Environmental Form of Aristolochic Acid Nephropathy.

Front Cardiovasc Med 2018 15;5:166. Epub 2018 Nov 15.

Department of Nephrology, Hypertension, Dialysis and Transplantation, School of Medicine, University Hospital Centre Zagreb, University of Zagreb, Zagreb, Croatia.

Balkan endemic nephropathy (BEN), an environmental form of aristolochic acid nephropathy is characterized with later onset and milder forms of hypertension (HT). Thus, we hypothesized that arterial stiffness progresses slower in BEN patients resulting in lower CV mortality. A total of 186 hemodialysed (HD) patients (90 BEN, 96 non-BEN; 67. Read More

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November 2018

Diamond/Porous Titanium Nitride Electrodes With Superior Electrochemical Performance for Neural Interfacing.

Front Bioeng Biotechnol 2018 15;6:171. Epub 2018 Nov 15.

Laboratory for Stem Cell Research, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.

Robust devices for chronic neural stimulation demand electrode materials which exhibit high charge injection () capacity and long-term stability. Boron-doped diamond (BDD) electrodes have shown promise for neural stimulation applications, but their practical applications remain limited due to the poor charge transfer capability of diamond. In this work, we present an attractive approach to produce BDD electrodes with exceptionally high surface area using porous titanium nitride (TiN) as interlayer template. Read More

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November 2018

The potential for improving cardio-renal outcomes by sodium-glucose co-transporter-2 inhibition in people with chronic kidney disease: a rationale for the EMPA-KIDNEY study.

Clin Kidney J 2018 Dec 25;11(6):749-761. Epub 2018 Oct 25.

Würzburg University Clinic, Würzburg, Germany.

Diabetes is a common cause of chronic kidney disease (CKD), but in aggregate, non-diabetic diseases account for a higher proportion of cases of CKD than diabetes in many parts of the world. Inhibition of the renin-angiotensin system reduces the risk of kidney disease progression and treatments that lower blood pressure (BP) or low-density lipoprotein cholesterol reduce cardiovascular (CV) risk in this population. Nevertheless, despite such interventions, considerable risks for kidney and CV complications remain. Read More

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December 2018

Do individual differences in the distribution of activation between synergist muscles reflect individual strategies?

Exp Brain Res 2018 Dec 6. Epub 2018 Dec 6.

Faculty of Sport Sciences, Laboratory "Movement, Interactions, Performance" (EA 4334), University of Nantes, 25 bis boulevard Guy Mollet, 44300, Nantes, France.

Individual differences in the distribution of activation between synergist muscles have been reported during a wide variety of tasks. Whether these differences represent actual individual strategies is unknown. The aims of this study were to: (i) test the between-day reliability of the distribution of activation between synergist muscles, (ii) to determine the robustness of these strategies between tasks, and to (iii) describe the inter-individual variability of activation strategies in a large sample size. Read More

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December 2018

Molecular epidemiology and clinical features of hand, foot and mouth disease in northern Thailand in 2016: a prospective cohort study.

BMC Infect Dis 2018 Dec 6;18(1):630. Epub 2018 Dec 6.

School of Health Science Research, Mae Fah Luang University, 333 Mo.1 Tasud Subdistrict, Muang District, Chiang Rai, Chiang Rai Province, 57100, Thailand.

Background: Hand, foot and mouth disease (HFMD) is a major communicable disease in children ≤6 years old, particularly in several countries in the Asia-Pacific Region, including Thailand. HFMD impacts public health and the economy, especially in northern Thailand.

Methods: A prospective cohort study was conducted to estimate the incidence rate and to identify the serotype and clinical features of HFMD among children in northern Thailand. Read More

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December 2018

Differential gene expression between the vigorous and dwarf litchi cultivars based on RNA-Seq transcriptome analysis.

PLoS One 2018 12;13(12):e0208771. Epub 2018 Dec 12.

State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources/Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (South China) in Ministry of Agriculture, College of Horticulture, South China Agricultural University, Guangzhou, China.

Litchi (Litchi chinesis Sonn.) is the most economically significant member of Sapindaceae family, especially in sub-tropical regions. However, its tall tree body often brings many inconveniences to production management. Read More

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December 2018

Development of a recombinase polymerase based isothermal amplification combined with lateral flow assay (HLB-RPA-LFA) for rapid detection of "Candidatus Liberibacter asiaticus".

PLoS One 2018 12;13(12):e0208530. Epub 2018 Dec 12.

Plant Virology Laboratory, ICAR-Indian Institute of Horticulture, Bengaluru, Karnataka, India.

Huanglongbing (HLB) or citrus greening is highly destructive disease that is affecting the citrus industry worldwide and it has killed millions of citrus plants globally. HLB is caused by the phloem limited, Gram negative, non-culturable, alpha-proteobacterium, 'Candidatus Liberibacter asiaticus'. Currently, polymerase chain reaction (PCR) and real time PCR have been the gold standard techniques used for detection of 'Ca. Read More

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December 2018
3 Reads

Usefulness of baseline statin therapy in non-obstructive coronary artery disease by coronary computed tomographic angiography: From the CONFIRM (COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter) study.

PLoS One 2018 12;13(12):e0207194. Epub 2018 Dec 12.

Department of Radiology, NewYork-Presbyterian Hospital and the Weill Cornell Medical College, New York, New York, United States of America.

Background: The extent to which the presence and extent of subclinical atherosclerosis by coronary computed tomography angiography influences a potential mortality benefit of statin is unknown. We evaluated the relationship between statin therapy, mortality, and subclinical atherosclerosis.

Methods: In the CONFIRM study, patients with normal or non-obstructive plaque (<50% diameter stenosis) for whom data on baseline statin use was available were included. Read More

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December 2018

Cardiac Index by Transthoracic Echocardiography (CITE) study.

PLoS One 2018 12;13(12):e0207269. Epub 2018 Dec 12.

Cardiology, Military Hospital State Health Centre, Budapest, Hungary.

Aims: Left ventricular ejection fraction (LVEF) is the most frequently used parameter in the assessment of heart failure (HF). Cardiac index (CI) is considered a potential alternative to LVEF despite limited evidence. We aimed to assess and compare the predictive accuracy of LVEF and echocardiographically-assessed CI in HF patients. Read More

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December 2018

Assessment and management of coronary artery disease in kidney and pancreas transplant candidates.

J Cardiovasc Med (Hagerstown) 2018 Dec 11. Epub 2018 Dec 11.

Department of Medicine, Bluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

: Patients with end-stage renal disease (ESRD) undergoing evaluation for kidney and/or pancreas transplantation represent a population with unique cardiovascular (CV) profiles and unique therapeutic needs. Coronary artery disease (CAD) is common in patients with ESRD, mediated by both the overrepresentation and higher prognostic value of traditional CV risk factors amongst this population, as well as altered cardiovascular responses to failing renal function, likely mediated by dysregulation of the renin-angiotensin-aldosterone system (RAAS) and abnormal calcium and phosphate metabolism. Within the ESRD population, obstructive CAD correlates highly with adverse coronary events, including during the peri-transplant period, and successful revascularization may attenuate some of that increased risk. Read More

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December 2018
1.407 Impact Factor

Optimisation of applied loads when using the two-point method for assessing the force-velocity relationship during vertical jumps.

Sports Biomech 2018 Dec 12:1-16. Epub 2018 Dec 12.

c Department of Kinesiology and Applied Physiology & Biomechanics and Movement Science Graduate Program , University of Delaware , Newark , DE , USA.

This study aimed to compare the reliability and validity of the force-velocity (F-V) relationship parameters obtained from two-point methods differing in the distance between experimental points, and to evaluate the acute change in unloaded jump height after a vertical jump testing procedure based on multiple loads. Totally, 18 men randomly performed two sessions of the squat jump (SJ) and two sessions of the countermovement jump (CMJ) exercises against five external loads (17, 30, 45, 60 and 75 kg). The unloaded jump height was evaluated before and after each testing procedure. Read More

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December 2018
2 Reads

Inter-Day Reliability of Finapres Cardiovascular Measurements During Rest and Exercise.

Sports Med Int Open 2018 Jan 17;2(1):E9-E15. Epub 2017 Nov 17.

St Mary's University Twickenham London, School of Sport, Health and Applied Sci, London, United Kingdom of Great Britain and Northern Ireland.

This study evaluated the inter-day test-retest reliability of the Finapres finger pulse pressure measuring device during rest and exercise. Eight male participants visited the laboratory twice for evaluation of the inter-day reliability of the Finapres finger-pulse pressure device to measure: heart rate (HR), stroke volume (SV), cardiac output (Q̇) and mean arterial pressure (MAP) at rest, and treadmill walking at 3 km/h on 1% and 5% inclines. There were no systematic biases for any of the variables between days. Read More

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January 2018

All-cause mortality, cardiovascular events, and health care costs after 12 months of dual platelet aggregation inhibition after acute myocardial infarction in real-world patients: findings from the Platelet-aggregation Inhibition: Persistence with treatment and cardiovascular Events in Real world (PIPER) study.

Vasc Health Risk Manag 2018 20;14:383-392. Epub 2018 Nov 20.

Department of Cardiology, Papa Giovanni XXIII Hospital, Bergamo, Italy.

Objectives: The aim of the study was to assess all-cause mortality and cardiovascular (CV) events in patients after a period of 12 months of treatment with dual antiplatelet therapy (DAPT) after hospitalization for acute myocardial infarction (AMI) in a real-world setting. Health care costs for the management of patients post-AMI was also assessed.

Methods: A retrospective analysis using data from the administrative databases of six local health units (LHUs) was performed. Read More

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November 2018

HER2-positive breast-cancer cell lines are sensitive to KDM5 inhibition: definition of a gene-expression model for the selection of sensitive cases.

Oncogene 2018 Dec 11. Epub 2018 Dec 11.

Laboratory of Molecular Biology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, via La Masa 19, 20157, Milano, Italy.

Targeting of histone methylation has therapeutic potential in oncology. Here, we provide proof-of-principle that pharmacological inhibition of KDM5 histone-demethylases is a new strategy for the personalized treatment of HER2 breast cancer. The anti-proliferative effects of the prototype of a new class of selective KDM5-inhibitors (KDM5-inh1) are evaluated in 40 cell lines, recapitulating the heterogeneity of breast cancer. Read More

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December 2018

Synthesis and evaluation of HfO2 as a prospective filler in inorganic-organic hybrid membranes based on Nafion for PEM fuel cells.

Nanotechnology 2018 Dec 11. Epub 2018 Dec 11.

SCIENCE, Centro de Investigacion y Desarrollo Tecnologico en Electroquimica SC, Pedro Escobedo, 76703, MEXICO.

Hybrid inorganic-organic Nafion membranes modified with metal oxides (typically TiO<sub>2</sub>, ZrO<sub>2</sub>, WO<sub>3</sub>) are a good alternative for fuel cells applications. However, one of their main limitations is associated with their relative low proton conductivity at temperatures above 80°C. In this work, we overcome this issue using HfO<sub>2</sub> as a filler. Read More

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December 2018

An LC-MS/MS method for quantification of abiraterone, its active metabolites D(4)-abiraterone (D4A) and 5α-abiraterone, and their inactive glucuronide derivatives.

J Chromatogr B Analyt Technol Biomed Life Sci 2018 Dec 4;1104:249-255. Epub 2018 Dec 4.

Pharmacogenomics Laboratory, Centre Hospitalier Universitaire (CHU) de Québec, - Université Laval Research Center and Faculty of Pharmacy, Laval University, Québec city, QC, Canada; Canada Research Chair in Pharmacogenomics, Canada. Electronic address:

Abiraterone acetate (AA) is a prodrug of abiraterone, a selective and potent steroidal cytochrome P450 17alpha- hydroxylase-17,20-lyase (CYP17A1) blocking androgen synthesis in the treatment of advanced prostate cancer. Abiraterone (Abi) is metabolized to D(4)-abiraterone (D4A) directly blocking CYP17A1 and other steroidogenic enzymes and antagonizing the androgen receptor (AR). D4A is converted by 5α-reductase to 3-keto-5α-abiraterone (5α-Abi), an AR agonist. Read More

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December 2018

Jasmonic acid and ethylene are involved in the accumulation of osmotin in germinating tomato seeds.

J Plant Physiol 2018 Nov 20;232:74-81. Epub 2018 Nov 20.

Department of Plant Physiology, Genetics and Biotechnology, University of Warmia and Mazury in Olsztyn, Oczapowskiego 1A, 10-718 Olsztyn, Poland.

The expression of SlNP24 encoding osmotin was studied in germinating tomato seeds Solanum lycopersicum L. cv. Moneymaker. Read More

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November 2018

Expression profiles of organogenesis-related genes over the time course of one-step de novo shoot organogenesis from intact seedlings of kohlrabi.

J Plant Physiol 2018 Nov 8;232:257-269. Epub 2018 Nov 8.

Institute for Biological Research "Siniša Stanković", University of Belgrade, Bulevar despota Stefana 142, 11060 Belgrade, Serbia.

Kohlrabi (Brassica oleracea var. gongylodes) is an important vegetable crop that is able to undergo shoot regeneration in culture from intact seedlings in a single-step regeneration process, using cytokinin as the only plant growth regulator. In this work, we present the expression profiles of seven organogenesis-related genes over the time course of shoot regeneration from intact seedlings of kohlrabi cv. Read More

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November 2018

Drought tolerance in alfalfa (Medicago sativa L.) varieties is associated with enhanced antioxidative protection and declined lipid peroxidation.

J Plant Physiol 2018 Oct 31;232:226-240. Epub 2018 Oct 31.

College of Grassland Science, Key Laboratory of Grassland Ecosystem (Ministry of Education), Pratacultural Engineering Laboratory of Gansu Province, Sino-U.S. Centers for Grazing Land Ecosystem Sustainability, Gansu Agricultural University, Lanzhou, 730070, China.

Drought stress is considered the most adverse factor restricting plant survival, growth, and productivity. The identification of the key adaptive mechanisms to drought stress is essential to enhance the drought resistance of plants. In this study, differential responses of three alfalfa varieties to drought, including Medicago sativa L. Read More

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October 2018
1 Read

Comparison of changes in water status and photosynthetic parameters in wild type and abscisic acid-deficient sitiens mutant of tomato (Solanum lycopersicum cv. Rheinlands Ruhm) exposed to sublethal and lethal salt stress.

J Plant Physiol 2018 Dec 8;232:130-140. Epub 2018 Dec 8.

Department of Plant Biology, University of Szeged, Közép fasor 52, H-6726, Szeged, Hungary.

Abscisic acid (ABA) regulates many salt stress-related processes of plants such as water balance, osmotic stress tolerance and photosynthesis. In this study we investigated the responses of wild type (WT) and the ABA-deficient sitiens mutant of tomato (Solanum lycopersicum cv. Rheinlands Ruhm) to sublethal and lethal salt stress elicited by 100 mM and 250 mM NaCl, respectively. Read More

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December 2018

Organ-specific differences in endogenous phytohormone and antioxidative responses in potato upon PSTVd infection.

J Plant Physiol 2018 Nov 4;232:107-114. Epub 2018 Nov 4.

Ruđer Bošković Institute, Bijenička cesta 54, 10000, Zagreb, Croatia. Electronic address:

Although structurally simple, viroids can trigger numerous changes in host plants and cause loss of yield in agronomically important crops. This study investigated changes in the endogenous status of phytohormones and antioxidant enzyme activity in Solanum tuberosum cv. Désirée in response to Potato spindle tuber viroid (PSTVd) infection. Read More

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November 2018

How Representative are the Patients Included in the CV outcome Trials with SGLT2 Inhibitors of a General Type 2 Diabetes Population? A Large European Observational study.

Diabetes Obes Metab 2018 Dec 9. Epub 2018 Dec 9.

University Medical Center Groningen and Bethesda Diabetes Research Center, The Netherlands.

Aims: Enrollment criteria vary substantially between the cardiovascular outcome trials (CVOTs) of sodium-glucose cotransporter-2 inhibitors (SGLT-2is), impacting how representative a trial population is to the general type 2 diabetes (T2D) population. The aim was to evaluate the representativeness of four SGLT-2i CVOTs to a general T2D population.

Methods: T2D patients were included from Germany, the Netherlands, Norway, and Sweden. Read More

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December 2018
2 Reads

Cucumis metuliferus reduces Meloidogyne incognita virulence against the Mi1.2 resistance gene in a tomato-melon rotation sequence.

Pest Manag Sci 2018 Dec 7. Epub 2018 Dec 7.

Department of Agri-Food Engineering and Biotechnology, Universitat Politècnica de Catalunya, Esteve Terradas 8, 08860 Castelldefels Barcelona, Spain.

Background: The susceptible tomato cv. Durinta, ungrafted or grafted onto cv. Aligator resistant rootstock, both followed by the susceptible melon cv. Read More

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December 2018

Pharmacokinetics and bioequivalence of generic and branded abiraterone acetate tablet: a single-dose, open-label, and replicate designed study in healthy Chinese male volunteers.

Cancer Chemother Pharmacol 2018 Dec 10. Epub 2018 Dec 10.

Phase I Clinical Trial Unit, Department of Pharmacy, Xuanwu Hospital Capital Medical University, Beijing, 100053, China.

Purpose: Abiraterone acetate is a highly variable drug and has been approved for the treatment of patients with metastatic castration-resistant prostate cancer in many countries. This study was conducted to compare the pharmacokinetic profile between the test product (abiraterone acetate tablet) and reference product ZYTIGA® (250 mg) mainly.

Methods: To overcome the high intra-subject variability of abiraterone, a two-sequence and four-period crossover study was designed to assess bioequivalence between the two products in 32 healthy male Chinese subjects under fasting conditions. Read More

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December 2018

Adenosine plasma level in patients with paroxysmal or persistent atrial fibrillation and normal heart during ablation procedure and/or cardioversion.

Purinergic Signal 2018 Dec 7. Epub 2018 Dec 7.

Department of Cardiology, Timone University Hospital, 13005, Marseille, France.

The mechanism of atrial fibrillation (AF) in patients with normal heart remains unclear. While exogenous adenosine can trigger AF, nothing is known about the behavior of endogenous adenosine plasma level (APL) at the onset of AF and during ablation procedure. Ninety-one patients (68 with paroxysmal AF: 40 males, 66 ± 16 years; 23 with persistent AF: 14 males, 69 ± 11 years) and 18 controls were included. Read More

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December 2018

Divergence between bread wheat and Triticum militinae in the powdery mildew resistance QPm.tut-4A locus and its implications for cloning of the resistance gene.

Theor Appl Genet 2018 Dec 7. Epub 2018 Dec 7.

Institute of Experimental Botany of the Czech Academy of Sciences, Centre of the Region Haná for Biotechnological and Agricultural Research, Šlechtitelů 31, 78371, Olomouc, Czech Republic.

A segment of Triticum militinae chromosome 7G harbors a gene(s) conferring powdery mildew resistance which is effective at both the seedling and the adult plant stages when transferred into bread wheat (T. aestivum). The introgressed segment replaces a piece of wheat chromosome arm 4AL. Read More

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December 2018

Cultivar and phosphorus effects on switchgrass yield and rhizosphere microbial diversity.

Appl Microbiol Biotechnol 2018 Dec 7. Epub 2018 Dec 7.

Department of Soil, Water and Climate, University of Minnesota, 439 Borlaug Hall, 1991 Upper Buford Circle, St. Paul, MN, 55108, USA.

Switchgrass (Panicum virgatum L.) is a native perennial grass identified as a promising biofuel crop for production on marginal agricultural lands. As such, research into switchgrass fertility and the switchgrass rhizosphere microbiome has been ongoing in an effort to increase production sustainability. Read More

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December 2018
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[Immunological and virological condition of adult patients with HIV infection at the beginning of antiretroviral therapy at Carlos van Buren Hospital. Comparison of 2013 and 2015 periods].

Rev Chilena Infectol 2018 ;35(3):326-328

Unidad de Infectología, Hospital Carlos van Buren, Universidad de Valparaíso, Chile.

Introduction: Anti-retroviral therapy (ART) in HIV patients has shown reduction in morbidity and mortality, and decrease in contagious risk. International recommendations include early initiation of ART, irrespectively of CD4 cell count.

Objective: To describe the impact of ART initiation in CD4 cell count and viral load at the end of the first year of HIV treatment, for patients who entered the program at 2013 and 2015. Read More

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January 2018

Tuning the deposition parameters for optimizing the faradaic and non-faradaic electrochemical performance of nanowire array-shaped ITO electrodes prepared by electron beam evaporation.

Nanoscale 2018 Dec 10. Epub 2018 Dec 10.

Institut de Ciència de Materials de Barcelona, ICMAB-CSIC, Campus UAB, E-08193 Bellaterra, Spain.

Nanostructured indium tin oxide (ITO) surfaces present an interesting yet unusual combination of properties (high electrical conductivity and optical transparency) at a high surface-to-volume ratio. Thus, previous studies presented nanostructured ITO electrodes as potentially suitable platforms for electrochemical biosensors, but still there is a lack of research on the optimization of preparation methods for such electrodes. We present a systematic study on the properties of nanostructured ITO electrodes prepared by physical deposition, where the substrate temperature was tuned for achieving the best combination of structural properties (namely electrical conductivity and optical transparency) and electrochemical performance. Read More

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December 2018
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The inter-visit variability of retinal blood flow velocity measurements using retinal function imager (RFI).

Eye Vis (Lond) 2018 4;5:31. Epub 2018 Dec 4.

1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Centre, Sun Yat-sen University, Xianlie Road 54, Guangzhou, 510060 China.

Background: To determine the inter-visit variability of retinal blood flow velocities (BFVs) using a retinal function imager (RFI) in healthy young subjects.

Methods: Twenty eyes of 20 healthy young subjects were enrolled. RFI imaging was performed to obtain the BFVs in retinal arterioles and venules in a field measuring 7. Read More

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December 2018