3,595 results match your criteria CSF Rhinorrhea


An uncommon etiological factor for aspiration pneumonitis caused by spontaneous sphenoid sinus meningoencephalocele with cerebrospinal fluid rhinorrhea: a case report.

BMC Pulm Med 2021 Jul 31;21(1):254. Epub 2021 Jul 31.

Department of Otolaryngology-Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, 264000, China.

Background: Aspiration pneumonitis is an inflammatory disease of the lungs which is difficult to diagnose accurately. Large-volume aspiration of oropharyngeal or gastric contents is essential for the development of aspiration pneumonitis. The role of cerebrospinal fluid (CSF) rhinorrhea is often underestimated as a rare etiological factor for aspiration in the diagnosis process of aspiration pneumonitis. Read More

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Use of Dental Bisphenol A-Glycidyl Methacrylate Composite to Repair Refractory Cerebrospinal Fluid Leaks Associated With Large-Scale Anterior Skull Base Defects.

J Craniofac Surg 2021 Jul-Aug 01;32(5):1805-1809

Department of Surgery, Faculty of Medicine and Biomedical Sciences, Yaounde Central Hospital, Yaounde, Cameroon.

Abstract: Treatment of refractory cerebrospinal fluid (CSF) leaks, particularly those associated with large skull base defects, is challenging. A variety of synthetic biomaterial-based systems have been investigated in experimental models and/or humans for reconstructing cranial base defects. A widely used dental composite (bisphenol A-glycidyl methacrylate [bis-GMA]) has been shown to be effective for reconstruction of anterior skull base defects in animal models. Read More

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Relationship between Recurrence Rates of Rathke's Cleft Cysts and Surgical Approaches to Sellar Reconstruction.

J Neurol Surg B Skull Base 2021 Jul 24;82(Suppl 3):e105-e111. Epub 2020 Jan 24.

Department of Neurosurgery, Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia.

 The main purpose of this article is to address the question of whether reconstructing the sellar floor following Rathke's cleft cyst excision results in increased rates of recurrence.  A retrospective case series was compiled from medical records and radiological investigations at a single institution over a time period spanning 25 years. Episodes of cyst recurrence were determined from magnetic resonance imaging scans and outpatient encounters. Read More

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Outcomes in Pediatric Transsphenoidal Pituitary Surgery Stratified by the Use of Image Guidance: An Analysis of the Kids' Inpatient Database from 1997 to 2016.

J Neurol Surg B Skull Base 2021 Jul 9;82(Suppl 3):e45-e50. Epub 2020 Mar 9.

Bobby R. Alford Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, United States.

 To evaluate the utilization of image guidance technology for pediatric transsphenoidal pituitary resection (TSPR) and analyze the complication rates, length of stay (LOS), and total cost for such surgeries as function of time and utilization of image guidance.  The Healthcare Cost and Utilization Project Kids' Inpatient Database (KID) was queried for all cases of TSPR between 1997 and 2016. Factors extracted included patient demographics, use of image guidance, LOS, total cost, and complications, including panhypopituitarism, diabetes insipidus (DI), cerebrospinal fluid (CSF) rhinorrhea, and cranial nerve (CN) III, IV, and VI palsies. Read More

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A Case of Traumatic Cerebrospinal Fluid Rhinorrhea Successfully Treated Using Intravenous Factor XIII Administration.

Cureus 2021 Jun 14;13(6):e15633. Epub 2021 Jun 14.

Department of Neurosurgery, Kesennuma City Hospital, Kesennuma, JPN.

Traumatic cerebrospinal fluid (CSF) rhinorrhea occurs around 2% of severe head trauma. We should find the fistula and surgically seal it or perform conservative therapy with bed rest with/without lumbar spinal CSF drainage. However, the fistula may not be identified, and treatment may sometimes be challenging. Read More

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A Cerebrospinal Case of Dyspnea.

Am J Med 2021 Jul 21. Epub 2021 Jul 21.

Department of Medicine, McGill University, Division of General Internal Medicine, Montreal, Quebec, Canada; Department of Medicine, McGill University, Division of Critical Care Medicine, Jewish General Hospital, Montreal, Quebec, Canada. Electronic address:

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Endoscopic Endonasal Approach for Giant Pituitary Adenoma Occupying the Entire Third Ventricle: Surgical Results and a Review of the Literature.

World Neurosurg 2021 Jul 20. Epub 2021 Jul 20.

Department of Neurosurgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, India. Electronic address:

Background: Pituitary macroadenomas occasionally disrupt the sellae diaphragma and extend directly to the third ventricle causing hydrocephalus. We present the results of a single-stage extended endoscopic approach for managing giant pituitary adenomas (GPAs) occupying the entire third ventricle.

Methods: A retrospective study of all GPAs occupying the entire third ventricle operated on via the endoscopic endonasal approach between January 2016 and December 2020 was performed. Read More

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Treatment of traumatic cerebrospinal fluid rhinorrhea via extended extradural anterior skull base approach.

Chin J Traumatol 2021 Jun 6. Epub 2021 Jun 6.

Department of Neurosurgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, 200072, China.

Objective: To describe and assess the repair technique and perioperative management for cerebrospinal fluid (CSF) leak resulting from extensive anterior skull base fracture via extradural anterior skull base approach.

Methods: This was a retrospective review conducted at the Department of Neurosurgery of the Shanghai Tenth People's Hospital from January 2015 to April 2020. Patients with traumatic CSF rhinorrhea resulting from extensive anterior skull base fracture treated surgically via extended extradural anterior skull base approach were included in this study. Read More

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[Basilar skull fractures].

Authors:
Josef Mohamad

Radiologe 2021 Aug 8;61(8):704-709. Epub 2021 Jul 8.

Klinik für Diagnostische und Interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, Kirrberger Straße 1, 66424, Homburg/Saar, Deutschland.

Clinical Issue: Basilar skull fractures are fractures of the lower part of the skull. They make up about 20% of all skull fractures and are mainly caused by high-velocity blunt trauma and falls from high heights. Depending on their precise location, they can be divided into frontobasal, laterobasal and frontolateral fractures. Read More

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A Novel Combined Transorbital Transnasal Endoscopic Approach for Reconstruction of Posttraumatic Complex Anterior Cranial Fossa Defect.

Asian J Neurosurg 2021 Jan-Mar;16(1):136-140. Epub 2021 Mar 20.

Department of Neurosurgery, Madras Medical College, Chennai, Tamil Nadu, India.

The transorbital neuroendoscopic surgery (TONES), endoscopic transnasal skull base procedures, and the concept of multiportal minimal access neurosurgery are novel, rapidly evolving approaches in the management of complex skull base lesions. A 27-year-old male presented with a history of road traffic accident with nasal bleed, cerebrospinal fluid (CSF) rhinorrhea, and left eye deformity. There was left upper eyelid ecchymosis, orbital dystopia, left pupil was dilated, and fixed with no extraocular movements. Read More

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Images: Unilateral rhinorrhea in a patient starting autotitrating positive airway pressure therapy for obstructive sleep apnea.

J Clin Sleep Med 2021 Jun 22. Epub 2021 Jun 22.

Henry Ford Sleep Disorders Center, Henry Ford Health System, Detroit, MI.

We rerpot a case of a 65-year-old obese female who developed a unilateral nasal cerebrospinal fluid (CSF) leak after starting autotitrating positive airway pressure therapy for obstructive sleep apnea. The CSF leak was confirmed by beta-2 transferrin testing of the nasal fluid, as well as by identification of the leak through the anterior cribriform plate after administration of intrathecal fluorescein. The CSF leak was successfully repaired endoscopically, and autotitrating positive airway pressure was reinitiated one month postoperatively. Read More

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A Comparitive Study of Endoscopic Skull Base Reconstruction in CSF rhinorrea using Nasoseptal Flap with  Septal Cartilage v/s Fascia Lata With Fat.

Indian J Otolaryngol Head Neck Surg 2021 Jun 11;73(2):233-239. Epub 2021 Mar 11.

Grant Government Medical College, Sir J.J. Group of Hospitals, Mumbai, India.

The objective of the study is to evaluate the surgical outcome between free nasoseptal mucoperichondrial flap using septal cartilage vs fascia lata using fat in terms of morbidity, hospital stay and postoperative complications. It is a retrospective comparitive study of 127 patients, diagnosed with CSF leak and who underwent repair of anterior skull base defect using free nasoseptal mucoperichondrial graft with septal cartilage in 73 cases compared with fascia lata with fat in 54 cases over the time frame of 5 years. The success rate with free nasoseptal flap with septal cartilage was 97. Read More

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A case report of cerebrospinal fluid leak secondary to inner ear malformation.

Radiol Case Rep 2021 Aug 7;16(8):1931-1933. Epub 2021 Jun 7.

Department of Radiology, Hanoi Medical University, Ha Noi, Vietnam.

Spontaneous cerebrospinal fluid (CSF) rhinorrhea is rare and may develop secondary to inner ear malformation. A possible diagnosis of CSF leak should be considered in any pediatric patient who presents with hearing impairment, rhinorrhea, or otorrhea. Temporal bone computed tomography should be performed in children with hearing impairments. Read More

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Transcranial extradural subtemporal repair for sphenoid sinus lateral recess meningoencephalocele: technical note.

Neurosurg Rev 2021 Jun 18. Epub 2021 Jun 18.

Department of Neurosurgery and Gamma Knife Radiosurgery, I.R.C.C.S. San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina, 60, 20132, Milan, Italy.

Cranial meningoencephalocele is a rare condition consisting of the herniation of meninges, CSF, and brain tissue through a cranial or skull base defect. Sphenoid sinus lateral recess meningoencephalocele is of particular interest due to the complex anatomy surrounding the bone defect and their demanding surgical management. In this technical note, we reported a step-by-step description of a rare case of sphenoid sinus lateral recess meningoencephalocele causing headache due to recurrent cerebrospinal fluid leak treated with a subtemporal craniotomy with extradural middle cranial fossa drilling and meningoencephalocele removal with multilayer reconstruction. Read More

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Matched Cohort Analysis of the Effect of the Facial Recess Approach on Cerebrospinal Fluid Leak After Translabyrinthine Surgery for Schwannoma.

Otol Neurotol 2021 Jun 11. Epub 2021 Jun 11.

Division of Neurotology Division of Neurosurgery, House Institute, Los Angeles, California.

Objective: The facial recess approach during translabyrinthine surgery has been used to expose the eustachian tube (ET) for packing. We sought to determine the effect of this technique on the development of postoperative nasopharyngeal cerebrospinal fluid (CSF) leaks.

Patients: Cohorts of patients with cerebellopontine angle schwannomas who underwent a facial recess approach or no facial recess approach were matched based on tumor size. Read More

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Bone Cement Internal Auditory Canal Reconstruction to Reduce CSF Leak After Vestibular Schwannoma Retrosigmoid Approach.

Otol Neurotol 2021 Jun 11. Epub 2021 Jun 11.

Johns Hopkins University, School of Medicine Johns Hopkins School of Medicine, Department of Otolaryngology-Head and Neck Surgery Johns Hopkins School of Medicine, Department of Neurosurgery, Baltimore, MD.

Objective: To describe rates of cerebrospinal fluid (CSF) rhinorrhea after reconstruction of the IAC with calcium phosphate bone cement during retrosigmoid resections of vestibular schwannomas.

Methods: A retrospective chart review of 177 patients who underwent retrosigmoid craniotomy and opening of the internal auditory canal for resection of a vestibular schwannoma between January 2016 and September 2019 at a tertiary referral center. Patients with other cerebellopontine angle tumor histology, neurofibromatosis type II, or those undergoing revision surgeries were excluded. Read More

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The meniscus sign: An endoscopic finding of cerebrospinal fluid rhinorrhea.

Int Forum Allergy Rhinol 2021 May 31. Epub 2021 May 31.

Department of Otolaryngology - Head and Neck Surgery, Tulane University, New Orleans, Louisiana, USA.

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Cerebrospinal Fluid Rhinorrhea as the First Symptom of Metastatic Prostate Adenocarcinoma.

Ear Nose Throat J 2021 May 26:1455613211016710. Epub 2021 May 26.

Department of Otolaryngology and Laryngological Oncology, Nicolaus Copernicus University in Torun, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland.

The most common cause of cerebrospinal fluid (CSF) rhinorrhoea is damage to the skull base with a dura mater's rupture due to an accident or an iatrogenic injury. This applies to over 96% of cases. Other possibilities that can lead to CSF leakage are neoplasms of the nasal cavity, paranasal sinuses, and nasopharynx. Read More

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Pseudo-Cerebrospinal Fluid Leaks of the Anterior Skull Base: Algorithm for Diagnosis and Management.

J Neurol Surg B Skull Base 2021 Jun 8;82(3):351-356. Epub 2019 Nov 8.

Department of Otorhinolaryngology, Universidad de Concepción, Concepción, Chile.

 Pseudo-cerebrospinal fluid (CSF) leaks are a rare cause of unilateral, watery rhinorrhea. We proposed a step-wise approach to evaluate these cases.  It involves a single-center retrospective cohort study. Read More

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COVID-19 swab-related skull base injury.

Med J Aust 2021 06 18;214(10):457-459.e1. Epub 2021 May 18.

Royal Brisbane and Women's Hospital, Brisbane, QLD.

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Reducing the risk of cerebrospinal fluid rhinorrhea following translabyrinthine surgery of the posterior fossa.

World J Otorhinolaryngol Head Neck Surg 2021 Apr 6;7(2):82-87. Epub 2021 Mar 6.

Department of Head and Neck Surgery & Communication Sciences, Duke University School of Medicine, Durham, NC, USA.

Objective: To describe the procedure and results of an adapted closure and reconstruction technique for translabyrinthine surgery that focuses on identifying and managing potential pathways for CSF egress to the middle ear and Eustachian tube.

Methods: Retrospective review of a cohort of translabyrinthine acoustic neuroma cases that were reconstructed using this technique.

Results: In addition to meticulous packing of potential conduits using soft tissue, hydroxyapatite cement is used to seal opened air cell tracts prior to obliteration of the mastoid defect using adipose tissue. Read More

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Reconstruction of Anterior Skull Base Fracture Using Autologous Fractured Fragments: A Simple Stitching-Up Technique.

Korean J Neurotrauma 2021 Apr 14;17(1):25-33. Epub 2021 Apr 14.

Department of Neurosurgery, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.

Objective: A displaced fracture in the anterior cranial base may be complicated by cerebrospinal fluid (CSF) rhinorrhea and enophthalmos. This study introduces a reconstruction technique with direct dural repair and reduction and fixation of the autologous fractured fragments.

Methods: Displaced fractures in the anterior cranial base were reconstructed using a stitching-up technique: A bicoronal scalp incision and frontal craniotomy was performed and the displaced bone was withdrawn. Read More

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The "Parachute" Technique for the Endoscopic Repair of High-Flow Anterior Skull-Base CSF Leaks.

World Neurosurg 2021 Jul 8;151:e880-e887. Epub 2021 May 8.

Department of Neurosurgery, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; "Aldo Ravelli" Research Center, Milan, Italy; Department of Medical-Surgical Physiopathology and Transplantation, University of Milan, Milan, Italy.

Objective: This study aims to assess the feasibility and reliability of our endoscopic trans-nasal technique for the repair of cribriform and sellar high-flow cerebrospinal fluid (CSF) leaks.

Methods: A comparison between patients suffering from high-flow rhinorrhea and treated through a free grafting endoscopic technique or the "parachute" technique, our nasal packing proposal, was performed.

Results: Thirty-three patients were included. Read More

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Unilateral Tension Pneumocephalus of the Sylvian Fissure: A Rare Neurosurgical Complication.

World Neurosurg 2021 Jul 30;151:87-88. Epub 2021 Apr 30.

Hospital Universitário Walter Cantídio/Universidade Federal do Ceará, Fortaleza, Brazil. Electronic address:

Tension pneumocephalus is an uncommon complication of neurosurgical procedures. We report a patient who presented with headache, vomiting, left hemiparesis and rhinorrhea 30 days after correction of a recurrent nasal cerebrospinal fluid fistula and shunt placement. A computed tomography scan revealed a massive collection of air with air-fluid level in the right sylvian fissure and midline shift. Read More

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Cerebrospinal fluid rhinorrhoea following nasal packing for epistaxis: case series from a single centre.

N Z Med J 2021 04 30;134(1534):143-145. Epub 2021 Apr 30.

Consultant ENT Surgeon, Department of Ear, Nose, Throat, Head & Neck surgery, Wellington Hospital, Capital & Coast district health board, Riddiford Street, Newtown, Wellington, New Zealand.

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Very Late Presentation of Csf Rhinorrhea after 45 Years of Head Trauma: A Case Report.

Iran J Otorhinolaryngol 2021 Mar;33(115):103-106

Department of Otorhinolaryngology, Ram Lal Eye and ENT Hospital, Government Medical College, Amritsar, Punjab.

Introduction: Very late presentation of cerebrospinal fluid rhinorrhea is quite rare with some factors like brain shrinkage with age and ethmoidal growth fracture that lead to leakage from fracture site.

Case Report: We present a 70 years old man diagnosing with CSF rhinorrhea, 45 years after head injury with metallic rod. Treatment of cerebrospinal fluid leakage was performed successfully by endoscopic intranasal repair. Read More

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Rhinorrhea following SARS-CoV-2 nasopharyngeal swab: A case for β2-transferrin testing.

Eur J Neurol 2021 Apr 26. Epub 2021 Apr 26.

Department of Neurology, Landesklinikum Mistelbach-Gänserndorf, Mistelbach, Austria.

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Repair of Giant Anterior Skull Base Encephalocele Containing Intralesional Eloquent Brain: Technical Note.

Oper Neurosurg (Hagerstown) 2021 07;21(2):73-80

Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Background: Encephaloceles are herniations of intracranial neural tissue and meninges through defects in the skull. Basal encephaloceles are rare anterior skull base defects incident in 1 in 35,000 live births. Sphenoethmoidal encephaloceles are even more uncommon, with an incidence of 1 in 700,000 live births. Read More

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Deployment of a bioabsorbable plate as the rigid buttress for skull base repair after endoscopic pituitary surgery.

Gland Surg 2021 Mar;10(3):1010-1017

Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan, China.

Background: Bioresorbable alloplastic implants have become desirable as a rigid buttress for reconstructing skull base defects. This study aimed to describe the use of a biodegradable plate (PolyMax RAPID) in skull base repair of endoscopic endonasal pituitary surgery and to investigate the clinical outcome and safety of this novel method.

Methods: Between January 2019 and January 2020, 22 patients with pituitary adenomas who underwent endoscopic skull base repair with a Polymax RAPID plate were included. Read More

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[Analysis of correlation between the pneumatization degree of paranasal sinuses and skull base and spontaneous cerebrospinal fluid rhinorrhea].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Mar;35(3):252-255

Department of Rhinology,the First Affiliated Hospital of Zhengzhou University,450052,Zhengzhou,China.

To investigate the relationship between the pneumatization degree of paranasal sinuses and skull base and the incidence of spontaneous cerebrospinal fluid rhinorrhea (SCSFR). Date of 107 patients with SCSFR were reviewed retrospectively. Using CT scans, investigator evaluated the pneumatization degree of paranasal sinuses and skull base, and compared classifications of various imaging characteristics between SCSFR group(case group) and nasal septum deviation group(control group), including frontal cells, Onodi cell, lateral recess of sphenoid sinus (LRSS), pneumatization of anterior clinoid process and pneumatization of posterior clinoid process. Read More

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