1,075 results match your criteria COPD: Journal of Chronic Obstructive Pulmonary Disease [Journal]


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COPD 2019 Apr 8. Epub 2019 Apr 8.

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http://dx.doi.org/10.1080/15412555.2018.1526364DOI Listing

Clinical Decision Support System: A Pragmatic Tool to Improve Acute Exacerbation of COPD Discharge Recommendations.

COPD 2019 Apr 4:1-7. Epub 2019 Apr 4.

a Department of Internal Medicine "B" , Rambam Health Care Campus , Haifa , Israel.

Acute exacerbations of chronic obstructive pulmonary disease (COPD) are associated with significant mortality, morbidity and increased risk for further exacerbations. Therefore, appropriate measures for prevention of further exacerbations should be initiated before discharge. Unfortunately, this opportunity for treatment review and change in disease course is often missed. Read More

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http://dx.doi.org/10.1080/15412555.2019.1593342DOI Listing
April 2019
2 Reads

Socioeconomic circumstances and incidence of chronic obstructive pulmonary disease (COPD) in an urban population in Sweden.

COPD 2019 Mar 27:1-7. Epub 2019 Mar 27.

b Department of Translational Medicine, Clinical Physiology and Nuclear Medicine , Lund University , Malmö , Sweden.

The association between socioeconomic circumstances and incidence of chronic obstructive pulmonary disease (COPD) was investigated in an urban population in Sweden. The study included all 40-89 year-old inhabitants in Malmö, Sweden (N = 117,479) without previous hospitalization due to COPD, who were followed over 14 years for COPD related hospital admissions. The Malmö Preventive Project (MPP) cohort (n = 27,358) with information on biological and lifestyle factors was also used to study the association between socioeconomic circumstances and COPD. Read More

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http://dx.doi.org/10.1080/15412555.2019.1582618DOI Listing
March 2019
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The Association between Chronic Obstructive Pulmonary Disease and Coronary Artery Disease in Patients Undergoing Coronary Angiography.

COPD 2019 Mar 22:1-6. Epub 2019 Mar 22.

a Department of Medicine and Mazankowski Alberta Heart Institute , University of Alberta , Edmonton , Alberta , Canada.

Chronic obstructive pulmonary disease (COPD) and coronary artery disease (CAD) are leading causes of morbidity and mortality. There are conflicting results regarding the association between COPD and CAD. We sought to measure the association between COPD and angiographically diagnosed CAD in a population-based cohort. Read More

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https://www.tandfonline.com/doi/full/10.1080/15412555.2019.1
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http://dx.doi.org/10.1080/15412555.2019.1566894DOI Listing
March 2019
10 Reads

Right Heart Catheterization During Exercise in Patients with COPD-An Overview of Clinical Results and Methodological Aspects.

COPD 2018 Dec;15(6):588-599

c DRK-Kliniken Berlin-Westend, Klinik für Kardiologie , Berlin , Germany.

While right heart catheterization (RHC) at rest is the gold standard to assess pulmonary hemodynamics in patients with chronic obstructive pulmonary disease (COPD) and pulmonary hypertension (PH), the invasive measurement of exercise hemodynamics is less well established in this group. Since exercise hemodynamics are increasingly recognized as important clinical information in patients with PH, our goal was to review the literature in this field to provide a basis for clinical use, further studies, and future recommendations. We identified 69 studies (published since 1968) reporting RHC data in 2819 patients with COPD, of whom 2561 underwent exercise testing. Read More

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http://dx.doi.org/10.1080/15412555.2018.1545832DOI Listing
December 2018
2 Reads

Bacterial Colonization in COPD Patients Admitted to a Rehabilitation Respiratory Unit and Impact on Length of Stay: A Real-Life Study.

COPD 2018 Dec;15(6):581-587

a Istituti Clinici Scientifici Maugeri IRCCS, Respiratory Rehabilitation of the Institute of Lumezzane , Brescia , Italy.

Bacterial colonization is a well-known phenomenon in acute care, but scant information is available regarding the rehabilitation setting. We retrospectively analyzed, in COPD patients admitted to a Respiratory Rehabilitative unit in 2010, the number of cultures requested, of positive cultures, and of cultures showing multiple drug resistant (MDR) organisms. We also compared hospital admissions (HA) with versus without positive cultures and with versus without MDR and investigated which baseline variables may predict length of stay (LOS) > 30 days. Read More

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http://dx.doi.org/10.1080/15412555.2019.1572731DOI Listing
December 2018
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Pulmonary Rehabilitation does not Improve Objective Measures of Sleep Quality in People with Chronic Obstructive Pulmonary Disease.

COPD 2019 Mar 19:1-5. Epub 2019 Mar 19.

c Discipline of Physiotherapy, Department of Physiotherapy, Alfred Health, Institute for Breathing and Sleep , La Trobe University , Melbourne , Australia.

Abnormal sleep duration is associated with poor health. Upwards of 50% of people with chronic obstructive pulmonary disease (COPD) report poor sleep quality. The effect of pulmonary rehabilitation on self-reported sleep quality is variable. Read More

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http://dx.doi.org/10.1080/15412555.2019.1567701DOI Listing
March 2019
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External Validation and Recalculation of the CODEX Index in COPD Patients. A 3CIAplus Cohort Study.

COPD 2019 Mar 14:1-10. Epub 2019 Mar 14.

ak Instituto de Investigación Hospital Universitario de la Princesa (IISP), Universidad Autónoma de Madrid, Cátedra UAM-Linde , Madrid , Spain.

The CODEX index was developed and validated in patients hospitalized for COPD exacerbation to predict the risk of death and readmission within one year after discharge. Our study aimed to validate the CODEX index in a large external population of COPD patients with variable durations of follow-up. Additionally, we aimed to recalculate the thresholds of the CODEX index using the cutoffs of variables previously suggested in the 3CIA study (mCODEX). Read More

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https://www.tandfonline.com/doi/full/10.1080/15412555.2018.1
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http://dx.doi.org/10.1080/15412555.2018.1484440DOI Listing
March 2019
13 Reads

Quality of Care Delivered to Veterans with COPD Exacerbation and the Association with 30-Day Readmission and Death.

COPD 2018 10;15(5):489-495

a Division of Pulmonary, Critical Care and Sleep Medicine , University of Washington , Seattle , Washington , USA.

Quality of chronic obstructive pulmonary disease (COPD) care is thought to be an important intermediate process to improve the well-being of patients admitted to hospital for exacerbation. We sought to examine the quality of inpatient COPD care and the associations with readmission and mortality. We performed a cohort study of 2,364 veterans aged over 40 and hospitalized for COPD between 2005 and 2011 at five Department of Veterans Affairs hospitals. Read More

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http://dx.doi.org/10.1080/15412555.2018.1543390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400327PMC
October 2018
1 Read

Observational Studies in COPD: Summary of Guidance for Authors.

COPD 2018 10;15(5):415-417

d School of Medical and Pharmaceutical Sciences , University of Genoa , Genova , Italy.

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http://dx.doi.org/10.1080/15412555.2018.1555234DOI Listing
October 2018
2 Reads

Association Between Chronic Obstructive Pulmonary Disease and Type 2 Diabetes: A Systematic Review and Meta-Analysis.

COPD 2018 10;15(5):526-535

a Respiratory Research Unit , Bispebjerg University Hospital , Copenhagen , Denmark.

Background: Chronic obstructive pulmonary disease (COPD) has been associated with an increased risk of type 2 diabetes (T2D). However, the mechanisms linking COPD and T2D is not fully understood and contradicting results are reported in the literature.

Aim: The aim of this study is to investigate whether COPD is associated with an increased risk of T2D. Read More

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http://dx.doi.org/10.1080/15412555.2018.1532495DOI Listing
October 2018

Oxidized Alpha-1-Antitrypsin as a Potential Biomarker Associated with Onset and Severity of Chronic Obstructive Pulmonary Disease in Adult Population.

COPD 2018 10;15(5):472-478

c Institute of Molecular Genetics and Genetic Engineering, University of Belgrade , Belgrade , Serbia.

Oxidative stress could reduce inhibitor activity of the alpha-1-antitrypsin (A1AT). Oxidative-modified A1AT (oxidized alpha-1-antitrypsin, OxyA1AT) significantly loses ability to protect the lungs from neutrophil elastase. We aimed to investigate OxyA1AT as a potential biomarker associated with onset and severity of chronic obstructive pulmonary disease (COPD) in adult population. Read More

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http://dx.doi.org/10.1080/15412555.2018.1541448DOI Listing
October 2018
1 Read

Comparative Effectiveness of Two Tiotropium Formulations: A Retrospective Cohort Study.

COPD 2018 10;15(5):418-423

a Pharmacoepidemiology Unit, National Center for Drug Research and Evaluation , National Institute of Health (ISS) , Rome , Italy.

The effectiveness of the tiotropium Respimat formulation in routine clinical practice is still an open issue due to concern about the generalizability of the Tiotropium Safety and Performance in Respimat (TIOSPIR) trial findings. Our aim was to compare the incidence of acute respiratory events between new users of tiotropium Respimat and HandiHaler. The study population comprised patients aged ≥45 years resident in two Italian regions who received a first tiotropium prescription (HandiHaler or Respimat) between 1 July 2011 and 30 November 2013. Read More

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http://dx.doi.org/10.1080/15412555.2018.1554032DOI Listing
October 2018
4 Reads

Prediction of COPD and Related Events Improves by Combining Spirometry and the Single Breath Nitrogen Test.

COPD 2018 10;15(5):424-431

c Department of Public Health and Caring Sciences , Family Medicine and Preventive Medicine Section, Uppsala University , Uppsala , Sweden.

Chronic obstructive pulmonary disease (COPD) develops in small airways. Severity of small airway pathology relates to progression and mortality. The present study evaluated the prediction of COPD of a validated test for small airway disease, i. Read More

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http://dx.doi.org/10.1080/15412555.2018.1538330DOI Listing
October 2018

Sedentary Behaviour and Physical Inactivity in Patients with Chronic Obstructive Pulmonary Disease: Two Sides of the Same Coin?

COPD 2018 10;15(5):432-438

a Laboratory of Research in Respiratory Physiotherapy (LFIP), Department of Physiotherapy , Universidade Estadual de Londrina (UEL) , Londrina , Brazil.

Despite the growing interest in sedentarism, there is no available information on the profile of patients with COPD according to sedentary behaviour (SB) and with a detailed analysis of minute-by-minute bouts. Hence, the aims of this study were to quantify the time spent in SB, light activities and moderate-to-vigorous physical activities (MVPA) and to verify the relationship of MVPA and SB in individuals with COPD, as well as to identify the profile of those physically (in)active and (non)-sedentary. A cross-sectional study in which physical activity in daily life was objectively assessed through the use of SenseWear Pro 2 Armband (BodyMedia) during 2 consecutive weekdays, 12 h/day. Read More

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http://dx.doi.org/10.1080/15412555.2018.1548587DOI Listing
October 2018

Successful Ageing with COPD: Physical and Psychosocial Adaption to Functional Decline.

COPD 2018 10;15(5):439-445

d Faculty of Business, Justice and Behavioural Studies , Charles Sturt University , Orange , Australia.

There is considerable research regarding the adaption to functional decline associated with advanced (Stage IV) Chronic Obstructive Pulmonary Disease (COPD). This research has, however, primarily focused on physical and interventional strategies to manage disease progression and symptom burden, as opposed to the psychosocial strategies. To address this paucity, the current research explored the psychosocial strategies people with Stage IV COPD use to maintain quality of life towards the end of life. Read More

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http://dx.doi.org/10.1080/15412555.2018.1487390DOI Listing
October 2018
1 Read

A Palliative Approach is Adopted for Many Patients Dying in Hospital with Chronic Obstructive Pulmonary Disease.

COPD 2018 10;15(5):503-511

e St Vincent's Hospital and Victorian Comprehensive Cancer Centre , University of Melbourne , Melbourne , Victoria , Australia.

Severe chronic breathlessness in advanced chronic obstructive pulmonary disease (COPD) is undertreated and few patients access specialist palliative care in the years before death. This study aimed to determine if symptom palliation or a palliative approach were delivered during the final hospital admission in which death occurred. Retrospective medical record audits were completed at two Australian hospitals, with all patients who died from COPD over 12 years between 1 January 2004 and 31 December 2015 included. Read More

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http://dx.doi.org/10.1080/15412555.2018.1549210DOI Listing
October 2018

Beta-Blockers in COPD: A Methodological Review of the Observational Studies.

COPD 2018 10;15(5):520-525

b Departments of Epidemiology and Biostatistics and of Medicine , McGill University , Montreal , Canada.

The use of beta-blockers in patients with chronic obstructive pulmonary disease (COPD) has received much attention. Several observational studies reported important reductions in mortality and exacerbations with these drugs, but the extent of bias in these studies is unclear. Nevertheless, the large ongoing randomized trial (βLOCK-COPD) was initiated specifically to evaluate these effects. Read More

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http://dx.doi.org/10.1080/15412555.2018.1554637DOI Listing
October 2018
2 Reads

Functional Electrical Stimulation Changes Muscle Oxygenation in Patients with Chronic Obstructive Pulmonary Disease During Moderate-Intensity Exercise: A Secondary Analysis.

COPD 2019 Mar 1:1-7. Epub 2019 Mar 1.

a Normandie Univ, UNIROUEN, EA3830-GRHV , Rouen , France.

We previously showed that functional electrical stimulation during cycle ergometry (FES-cycling) increased oxygen consumption (VO), indicating that metabolism during exercise was increased. However, the effects on muscle oxygenation have never been studied. The aim of this secondary analysis was to analyse changes in muscle oxygenation during an FES-cycling session. Read More

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http://dx.doi.org/10.1080/15412555.2018.1560402DOI Listing

Predictors of New Airway Obstruction - An 11 Year's Population-Based Follow-Up Study.

COPD 2019 Mar 1:1-6. Epub 2019 Mar 1.

a University of Turku, Division of Medicine, Department of Pulmonary Diseases and Clinical Allergology , Turku University Hospital and University of Turku , Turku , Finland.

In the present study we aimed to investigate the incidence and predictors of spirometry based airway obstruction in a representative population-based sample. Altogether 3,863 subjects, 1,651 males and 2,212 females aged ≥30 years had normal spirometry in year 2000. Fifty-three percent of them were never and 23% current smokers. Read More

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http://dx.doi.org/10.1080/15412555.2019.1576163DOI Listing
March 2019
1 Read

Assessment of Self-Management Treatment Needs Among COPD Helpline Callers.

COPD 2019 Feb 21:1-7. Epub 2019 Feb 21.

b Department of Preventive Medicine , Northwestern University Feinberg School of Medicine , Chicago , Illinois , USA.

Telephone quitlines are an effective population-based strategy for smoking cessation, particularly among individuals with tobacco-related diseases such as chronic obstructive pulmonary disease (COPD). Expanding quitline services to provide COPD-focused self-management interventions is potentially beneficial; however, data are needed to identify specific treatment needs in this population. We conducted a telephone-based survey (N = 5,772) to examine educational needs, behavioral health characteristics, and disease-related interference among individuals with COPD who received services from the American Lung Association (ALA) Lung Helpline. Read More

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http://dx.doi.org/10.1080/15412555.2019.1575350DOI Listing
February 2019
1 Read

Practical Guide to the Identification and Diagnosis of Asthma-COPD Overlap (ACO).

COPD 2019 Feb 21:1-7. Epub 2019 Feb 21.

a Pneumology Department , University Hospital Vall d'Hebron/Vall d'Hebron Research Institute (VHIR) , Barcelona , Spain.

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of mortality around the world. COPD is characterised by a heterogeneous clinical presentation and prognosis which may vary according to the clinical phenotype. One of the phenotypes of COPD most frequently studied is the asthma-COPD overlap (ACO), however, there are no universally accepted diagnostic criteria for ACO. Read More

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http://dx.doi.org/10.1080/15412555.2019.1575802DOI Listing
February 2019

Perspectives on End-of-Life Treatment among Patients with COPD: A Multicenter, Cross-sectional Study in Japan.

COPD 2019 Feb 21:1-7. Epub 2019 Feb 21.

a Department of Respiratory Medicine, Graduate School of Medicine , Kyoto University , Kyoto , Japan.

Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality. Since patients with severe COPD may experience exacerbations and eventually face mortality, advanced care planning (ACP) has been increasingly emphasized in the recent COPD guidelines. We conducted a multicenter, cross-sectional study to survey the current perspectives of Japanese COPD patients toward ACP. Read More

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http://dx.doi.org/10.1080/15412555.2019.1573888DOI Listing
February 2019
1 Read

National Survey on the Management of Adult Bronchiectasis in Belgium.

COPD 2019 Feb 21:1-3. Epub 2019 Feb 21.

a Department of Respiratory Medicine , University Hospitals Leuven , Leuven , Belgium.

The increasing prevalence and incidence of bronchiectasis leads to a substantial health care burden. Quality standards for the management of bronchiectasis were formulated by the British Thoracic Society following publication of guidelines in 2010. They can be used as a benchmark for quality of care. Read More

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http://dx.doi.org/10.1080/15412555.2019.1566895DOI Listing
February 2019

Prevalence of Comorbid Chronic Obstructive Pulmonary Disease in Individuals Suffering from Schizophrenia and Bipolar Disorder: A Systematic Review.

COPD 2018 Dec 4;15(6):612-620. Epub 2019 Feb 4.

a Department of Pulmonology , School of Health Science, University of Patras , Patras , Greece.

The disease burden associated with schizophrenia and bipolar disorder is substantial, with affected individuals having a shorter life expectancy and a high risk of severe physical comorbid conditions. These individuals are more likely to smoke and have a longer smoking history compared to the general population. Furthermore, use of antipsychotic drugs has also been linked to active smoking. Read More

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http://dx.doi.org/10.1080/15412555.2019.1572730DOI Listing
December 2018
3 Reads

Palliative Care Provision for Patients with Advanced Chronic Obstructive Pulmonary Disease: A Systematic Integrative Literature Review.

COPD 2018 Dec 4;15(6):600-611. Epub 2019 Feb 4.

c International Observatory on End of Life Care, Faculty of Health and Medicine, Lancaster University, Lancaster , UK.

Although chronic obstructive pulmonary disease (COPD) is recognized as being a life-limiting condition with palliative care needs, palliative care provision is seldom implemented. The disease unpredictability, the misconceptions about palliative care being only for people with cancer, and only relevant in the last days of life, prevent a timely integrated care plan. This systematic review aimed to explore how palliative care is provided in advanced COPD and to identify elements defining integrated palliative care. Read More

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http://dx.doi.org/10.1080/15412555.2019.1566893DOI Listing
December 2018
12 Reads

Mucus Hydration in Subjects with Stable Chronic Bronchitis: A Comparison of Spontaneous and Induced Sputum.

COPD 2018 Dec 4;15(6):572-580. Epub 2019 Feb 4.

c Marsico Lung Institute/Cystic Fibrosis Research Center, University of North Carolina at Chapel Hill , Chapel Hill , North Carolina , USA.

Mucus hydration is important in mucus clearance and lung health. This study sought to test the relative utility of spontaneous sputum (SS) versus the reasonably noninvasive induced sputum (IS) samples for measurement of mucus hydration. SS and IS samples were collected over a 2-day study interval. Read More

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http://dx.doi.org/10.1080/15412555.2019.1566892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428611PMC
December 2018
2 Reads

The role of physical activity in the context of pulmonary rehabilitation.

COPD 2018 Dec 4;15(6):632-639. Epub 2019 Feb 4.

a Department of Rehabilitation Sciences , KU Leuven - University of Leuven , Leuven , Belgium.

Pulmonary rehabilitation is an important treatment for patients with chronic obstructive pulmonary disease (COPD). Although this intervention leads to large and clinically meaningful improvements in exercise capacity and quality of life, the effect of pulmonary rehabilitation on physical activity is controversial. Physical activity is lower in patients with COPD as compared to healthy age-matched controls and it is related to important health outcomes (e. Read More

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http://dx.doi.org/10.1080/15412555.2018.1563060DOI Listing
December 2018
2 Reads

Adenosine Metabolism in COPD: A Study on Adenosine Levels, 5'-Nucleotidase, Adenosine Deaminase and Its Isoenzymes Activity in Serum, Lymphocytes and Erythrocytes.

COPD 2018 Dec 19;15(6):559-571. Epub 2019 Jan 19.

a Department of Biochemistry , Vallabhbhai Patel Chest Institute, University of Delhi , Delhi , India.

Adenosine is a signaling molecule which is produced in high concentrations during airway inflammation. Airway inflammation is a characteristic feature of COPD. Therefore, the current study was designed to evaluate the changes in adenosine metabolism in COPD and correlate these changes with severity of the disease. Read More

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http://dx.doi.org/10.1080/15412555.2018.1537365DOI Listing
December 2018
1 Read

Spirometric instability - another hurdle in achieving real-world COPD diagnostic criteria?

COPD 2018 Dec 30;15(6):557-558. Epub 2018 Dec 30.

b Department of Clinical Medical Sciences, Faculty of Medical Sciences , The University of the West Indies, St Augustine Campus , Trinidad and Tobago.

Globally, mortality, morbidity and the economic burden of chronic obstructive pulmonary disease (COPD) are on the rise. In addition, its diagnosis continues to pose challenges to the physicians, which is compounded further by its new feature "spirometric instability." Based on the findings from the two recent observational studies, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommended repeat spirometry for the individuals with a fixed ratio between 0. Read More

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http://dx.doi.org/10.1080/15412555.2018.1534947DOI Listing
December 2018
1 Read

The Role of Cardiopulmonary Exercise Testing (CPET) in Pulmonary Rehabilitation (PR) of Chronic Obstructive Pulmonary Disease (COPD) Patients.

COPD 2018 Dec 30;15(6):621-631. Epub 2018 Dec 30.

b Respiratory Research Center, Royal University Hospital , University of Saskatchewan , Saskatoon , Canada.

Chronic obstructive pulmonary disease (COPD) is a common multisystem inflammatory disease with ramifications involving essentially all organ systems. Pulmonary rehabilitation is a comprehensive program designed to prevent and mitigate these disparate systemic effects and improve patient quality of life, functional status, and social functioning. Although initial patient assessment is a prominent component of any pulmonary rehabilitation (PR) program, cardiopulmonary exercise testing (CPET) is not regularly performed as a screening physiologic test prior to PR in COPD patients. Read More

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http://dx.doi.org/10.1080/15412555.2018.1550476DOI Listing
December 2018
6 Reads

Obesity in COPD: Comorbidities with Practical Consequences?

COPD 2018 10 4;15(5):464-471. Epub 2018 Dec 4.

a Department of Pulmonary Disease , Rijnstate hospital , Arnhem , Netherlands.

COPD and obesity often coexist and there is a complex interaction between them. Our aim was to evaluate the prevalence of obesity in a secondary care COPD population. Furthermore, the presence of comorbidities in obese (COPD) and non-obese COPD (COPD) individuals was studied. Read More

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https://www.tandfonline.com/doi/full/10.1080/15412555.2018.1
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http://dx.doi.org/10.1080/15412555.2018.1509951DOI Listing
October 2018
17 Reads

Minimal Important and Detectable Differences of Respiratory Measures in Outpatients with AECOPD.

COPD 2018 10 4;15(5):479-488. Epub 2018 Dec 4.

b Lab 3R - Respiratory Research and Rehabilitation Laboratory, School of Health Sciences , University of Aveiro , Aveiro , Portugal.

Interpreting clinical changes during acute exacerbations of chronic obstructive pulmonary disease (AECOPD) is challenging due to the absence of established minimal detectable (MDD) and important (MID) differences for most respiratory measures. This study established MDD and MID for respiratory measures in outpatients with AECOPD following pharmacological treatment. COPD assessment test (CAT), modified Borg scale (MBS), modified British Medical Research Council (mMRC) questionnaire, peripheral oxygen saturation (SpO), computerised respiratory sounds and forced expiratory volume in one second (FEV) were collected within 24-48 hour of an AECOPD and after 45 days of pharmacological treatment. Read More

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https://www.tandfonline.com/doi/full/10.1080/15412555.2018.1
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http://dx.doi.org/10.1080/15412555.2018.1537366DOI Listing
October 2018
13 Reads

Pattern of Cardiovascular Comorbidity in COPD in a Country with Low-smoking Prevalence: Results from Two-population-based Cohorts from Sweden.

COPD 2018 10 26;15(5):454-463. Epub 2018 Nov 26.

a Krefting Research Centre , Institute of Medicine, University of Gothenburg , Gothenburg , Sweden.

Cardiovascular diseases are the most common comorbidities in COPD, due to common risk factors such as smoking. The prevalence of current smokers in Sweden has decreased over four decades to around 10%. The aim of the present study was to investigate the prevalence, distribution and associations of cardiovascular comorbidities in COPD by disease severity in two large areas of Sweden, both with low-smoking prevalence. Read More

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http://dx.doi.org/10.1080/15412555.2018.1535580DOI Listing
October 2018
16 Reads

Monitoring Antioxidant Enzyme Activity during Exacerbations of Chronic Obstructive Pulmonary Disease.

COPD 2018 10 26;15(5):496-502. Epub 2018 Nov 26.

a Department of Pathophysiology , National Koranyi Institute for TB and Pulmonology , Budapest , Hungary.

Superoxide dismutases (SODs) and catalase (CAT) have been implicated as major antioxidant enzymes of the human lungs. In this study, we investigated whether activities of these enzymes are altered in the airways of patients hospitalized with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). SOD and CAT activities were measured in the sputum, exhaled breath condensate, and serum of 36 COPD patients experiencing a severe exacerbation. Read More

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https://www.tandfonline.com/doi/full/10.1080/15412555.2018.1
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http://dx.doi.org/10.1080/15412555.2018.1535581DOI Listing
October 2018
18 Reads

COPD Assessment Test (CAT) is a Valid and Simple Tool to Measure the Impact of Bronchiectasis on Affected Patients.

COPD 2018 10 23;15(5):512-519. Epub 2018 Nov 23.

a Postgraduate Program in Rehabilitation Sciences , Universidade Nove de Julho - UNINOVE , São Paulo , Brazil.

The COPD assessment test (CAT) is a short questionnaire developed to help patients and clinicians to assess the impact of symptoms in routine clinical practice. We aimed to validate and to test the reproducibility of CAT in patients with bronchiectasis and correlate with the severity of dyspnea, aerobic and functional capacity, and physical activity in daily life. This is a cross-sectional study, patients with bronchiectasis underwent spirometry, cardiopulmonary exercise test (CPET), incremental shuttle walk test (ISWT), Saint George`s Respiratory Questionnaire (SGRQ), and received pedometer. Read More

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http://dx.doi.org/10.1080/15412555.2018.1540034DOI Listing
October 2018
13 Reads

Role of Stem Cells in the Pathogenesis of Chronic Obstructive Pulmonary Disease and Pulmonary Emphysema.

COPD 2018 10 23;15(5):536-556. Epub 2018 Nov 23.

a Dipartimento di Scienze Biomediche, Unità Operativa Complessa di Pneumologia , Odontoiatriche e delle Immagini Morfologiche e Funzionali (BIOMORF), Università degli Studi di Messina , Messina , Italy.

There are only few human translational studies performed in the area of stem cell research in patients with chronic obstructive pulmonary disease (COPD) and/or pulmonary emphysema. Before progress to clinical trials with stem cells we strongly believe that more human translational studies are essential, otherwise, the clinical rationale would be solely based on limited in vitro and animal studies. In the future, stem cell therapy could be a treatment for this incurable disease. Read More

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https://www.tandfonline.com/doi/full/10.1080/15412555.2018.1
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http://dx.doi.org/10.1080/15412555.2018.1536116DOI Listing
October 2018
16 Reads

The Impact of Loneliness on Outcomes of Pulmonary Rehabilitation in Patients with COPD.

COPD 2018 10 7;15(5):446-453. Epub 2018 Nov 7.

a Health Psychology , University of Leuven , Leuven , Belgium.

Psychological factors such as negative affect have been demonstrated to impact course and treatment of chronic obstructive pulmonary disease (COPD). However, little is known about the respective impact of social factors. In several other chronic diseases, loneliness has been shown to predict morbidity, but little is known about its impact on COPD. Read More

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https://www.tandfonline.com/doi/full/10.1080/15412555.2018.1
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http://dx.doi.org/10.1080/15412555.2018.1471128DOI Listing
October 2018
25 Reads

Health Status in Patients with COPD According to GOLD 2017 Classification: Use of the COMCOLD Score in Routine Clinical Practice.

COPD 2018 Jun-Aug;15(4):326-333. Epub 2018 Nov 6.

a Hospital Universitario Nuestra Señora de la Candelaria , Santa Cruz de Tenerife , Spain.

The COMCOLD score was developed to quantify the impact of comorbidities on health status in patients with chronic obstructive pulmonary disease (COPD). The objective of this study is to evaluate the association between health status in outpatients with COPD according to COMCOLD score and the GOLD 2017 groups according to symptoms (B and D vs. A and C) and exacerbations (C and D vs. Read More

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https://www.tandfonline.com/doi/full/10.1080/15412555.2018.1
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http://dx.doi.org/10.1080/15412555.2018.1531388DOI Listing
November 2018
22 Reads

Combining the Pulmonary Rehabilitation Decisional Score with the Bode Index and Clinical Opinion in Assigning Priority for Pulmonary Rehabilitation.

COPD 2018 06 6;15(3):238-244. Epub 2018 Nov 6.

a Istituti Clinici Scientifici Maugeri IRCCS, Scientific Direction of the Institute of Lumezzane , Brescia , Italy.

Combining objective tools with clinical decision (CD) may help clinicians identify the priority for pulmonary rehabilitation (PR) in patients with COPD. We aimed to assess the specificity, sensitivity and efficiency of a new tool, the Pulmonary Rehabilitation Decisional Score (PRDS), and its correlation with the BODE index (BI) and CD in assigning PR priority. We retrospectively compared the three methods (CD vs. Read More

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http://dx.doi.org/10.1080/15412555.2018.1531389DOI Listing
June 2018
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Current Status of Pulmonary Rehabilitation: Introductory Remarks on Pulmonary Rehabilitation, the Importance and the Practice.

COPD 2018 06 2;15(3):215-218. Epub 2018 Nov 2.

b School of Medical and Pharmaceutical Sciences , University of Genoa , Genoa , Italy.

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http://dx.doi.org/10.1080/15412555.2018.1478398DOI Listing
June 2018
3 Reads

Geographical Distribution of COPD Prevalence in the Americas.

COPD 2018 Jun-Aug;15(4):317-325. Epub 2018 Oct 30.

f Pneumology Department , Hospital Universitari Vall d'Hebron , Barcelona , Spain.

Surveys estimating chronic obstructive pulmonary disease (COPD) prevalence are unevenly distributed in the Americas, which make it difficult to estimate accurately its geographical distribution. The geographic information system inverse distance weighted (IDW) interpolation technique has proved to be an effective tool in spatial distribution estimation of epidemiological variables, even when real data are few or widely spread. We aimed to represent cartographically the COPD prevalence in the Americas by means of a blue to red scale representation of the prevalence data, where different values are represented as different colours, and a population density filtered IDW interpolation mapping, where areas with a population density <0. Read More

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https://www.tandfonline.com/doi/full/10.1080/15412555.2018.1
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http://dx.doi.org/10.1080/15412555.2018.1481936DOI Listing
October 2018
21 Reads

Postoperative outcomes of frequent exacerbator patients with Chronic Obstructive Pulmonary Disease after resection of Non-Small Cells Lung Cancer.

COPD 2018 Jun-Aug;15(4):361-368. Epub 2018 Oct 30.

c Departement of Thoracic Surgery, Paris Center University Hospital , Paris Descartes University , Paris , France.

Chronic obstructive pulmonary disease (COPD) is a risk factor of post-operative complications after lung cancer resection. The influence of the "frequent exacerbator (FE)" phenotype (at least three exacerbations per year) is unknown. Postoperative outcomes of frequent exacerbators (POFE) was a prospective observational study of patients with COPD undergoing lung resection for cancer. Read More

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https://www.tandfonline.com/doi/full/10.1080/15412555.2018.1
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http://dx.doi.org/10.1080/15412555.2018.1519784DOI Listing
October 2018
20 Reads

Analysis of Autonomic Modulation in Response to a Session of Aerobic Exercise at Different Intensities in Patients With Moderate and Severe COPD.

COPD 2018 Oct 30:1-9. Epub 2018 Oct 30.

a Department of Physiotherapy , Universidade Estadual Paulista (UNESP) , São Paulo , Brazil.

Despite the many benefits of performing physical exercise in patients with chronic obstructive pulmonary disease (COPD), information on the response of acute cardiac autonomic modulation in subjects with moderate and severe COPD during and after an aerobic exercise session at different intensities is unknown. The aim of this study was to evaluate the response of cardiac autonomic modulation in patients with moderate and severe COPD during and after an aerobic exercise session at different intensities. Twenty-seven patients with COPD, divided into: Moderate Group and Severe Group, underwent an aerobic exercise sessions with intensities equivalent to 60% and 90% of velocity corresponding to peak oxygen consumption. Read More

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http://dx.doi.org/10.1080/15412555.2018.1529744DOI Listing
October 2018
19 Reads

Correction.

Authors:

COPD 2018 06 2;15(3):314-315. Epub 2018 Oct 2.

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http://dx.doi.org/10.1080/15412555.2018.1518204DOI Listing
June 2018
1 Read

Correction.

Authors:

COPD 2018 06 2;15(3):313. Epub 2018 Oct 2.

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http://dx.doi.org/10.1080/15412555.2018.1509830DOI Listing
June 2018
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Comorbidities and length of stay in chronic obstructive pulmonary disease patients.

COPD 2018 Jun-Aug;15(4):355-360. Epub 2018 Oct 1.

c University of North Carolina-Charlotte , Charlotte , North Carolina , USA.

Chronic Obstructive Pulmonary Disease (COPD) has a significant burden on patients and the healthcare system. There is a link between COPD and comorbidities such as congestive heart failure (CHF), fluid and electrolyte disorders, and renal failure. This adds to the complexity of healthcare in these patients. Read More

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http://dx.doi.org/10.1080/15412555.2018.1513470DOI Listing
October 2018
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The Efficacy and Safety of Once-daily Fluticasone Furoate/Umeclidinium/Vilanterol Versus Twice-daily Budesonide/Formoterol in a Subgroup of Patients from China with Symptomatic COPD at Risk of Exacerbations (FULFIL Trial).

COPD 2018 Jun-Aug;15(4):334-340. Epub 2018 Sep 28.

k GSK , King of Prussia , PA , USA.

The FULFIL study evaluated once-daily fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) 100 µg/62.5 µg/25 µg versus twice-daily budesonide/formoterol (BUD/FOR) 400 µg/12 µg in patients with symptomatic COPD at risk of exacerbations. FULFIL demonstrated clinically meaningful and statistically significant improvements at Week 24 in trough forced expiratory volume in 1 second (FEV), St George's Respiratory Questionnaire (SGRQ) Total scores and reduced exacerbation frequency. Read More

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http://dx.doi.org/10.1080/15412555.2018.1481022DOI Listing
September 2018
9 Reads

Prevalence and Predictors of Obstructive Sleep Apnea in Patients with Chronic Obstructive Pulmonary Disease Undergoing Inpatient Pulmonary Rehabilitation.

COPD 2018 06 21;15(3):265-270. Epub 2018 Sep 21.

a Respiratory Intensive Care Unit and Pulmonary Rehabilitation Unit , Istituti Clinici Scientifici Maugeri IRCCS, Istituto Scientifico di Pavia , Pavia , Italy.

The aim of our study was to evaluate the prevalence and predictors of obstructive sleep apnea (OSA) in patients with chronic obstructive pulmonary disease (COPD) undergoing inpatient pulmonary rehabilitation programs (PRPs). A retrospective data review of consecutive stable patients with a known diagnosis of COPD, admitted for PRP between January 2007 and December 2013. Full overnight polysomnography (PSG) and Epworth Sleepiness Scale (ESS) were assessed in all patients. Read More

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http://dx.doi.org/10.1080/15412555.2018.1500533DOI Listing
June 2018
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Differing Approaches to Managing the Chronic Breathlessness Syndrome in Advanced COPD: A Multi-National Survey of Specialists.

COPD 2018 06 11;15(3):294-302. Epub 2018 Sep 11.

f Palliative Medicine , St Vincent's Hospital and Victorian Comprehensive Cancer Centre, University of Melbourne.

This study explored the approaches of respiratory and palliative medicine specialists to managing the chronic breathlessness syndrome in patients with severe chronic obstructive pulmonary disease. A voluntary, online survey was emailed to all specialists and trainees in respiratory medicine in Australia and New Zealand (ANZ), and to all palliative medicine specialists and trainees in ANZ and the United Kingdom (UK). Five hundred and seventy-seven (33. Read More

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https://www.tandfonline.com/doi/full/10.1080/15412555.2018.1
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http://dx.doi.org/10.1080/15412555.2018.1502264DOI Listing
June 2018
12 Reads