79 results match your criteria CNS Imaging in Cysticercosis

Porcine model of neurocysticercosis by intracarotid injection of Taenia solium oncospheres: Dose assessment, infection outcomes and serological responses.

PLoS Negl Trop Dis 2022 06 2;16(6):e0010449. Epub 2022 Jun 2.

Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru.

Background: Neurocysticercosis (NCC) is the infection of the human central nervous system (CNS) by Taenia solium larvae that cause significant neurological morbidity. Studies on NCC pathophysiology, host-parasite interactions or therapeutic agents are limited by the lack of suitable animal models. We have previously reported that carotid injection of activated T. Read More

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Taenia multiceps coenurosis: a review.

Parasit Vectors 2022 Mar 12;15(1):84. Epub 2022 Mar 12.

Department of Veterinary Medicine, Veterinary Teaching Hospital, University of Sassari, Sassari, Italy.

Taenia multiceps is a taeniid cestode that inhabits the small intestines of both wild and domestic carnivores. The larval stage, Coenurus cerebralis, is typically found in the central nervous system (CNS) of a wide range of livestock and, to a lesser extent, in the extra-cerebral tissues of sheep and goats. This review covers all aspects of the life cycle of T. Read More

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A Rare Case of Cysticercosis Involving the Whole Spinal Canal.

Acta Parasitol 2022 Mar 1;67(1):569-572. Epub 2021 Dec 1.

Emergency and Critical Care Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Background: Cysticercosis is the commonest parasitic disease to affect the central nervous system (CNS). However, cysticercosis affecting the spine is extremely rare. We reported a rare case of cysticercosis involving the whole spinal canal in China. Read More

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Next-generation sequencing combined with serological tests based pathogen analysis for a neurocysticercosis patient with a 20-year history:a case report.

BMC Neurol 2021 Jun 24;21(1):236. Epub 2021 Jun 24.

Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Background: Neurocysticercosis (NCC) is the most common helminthic infection of the central nervous system (CNS) caused by the larval stage of Taenia solium. Accurate and early diagnosis of NCC remains challenging due to its heterogeneous clinical manifestations, neuroimaging deficits, variable sensitivity, and specificity of serological tests. Next-generation sequencing (NGS)-based pathogen analysis in patient's cerebrospinal fluid (CSF) with NCC infection has recently been reported indicating its diagnostic efficacy. Read More

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Psychiatric Disorders of Neurocysticercosis: Narrative Review.

Neuropsychiatr Dis Treat 2021 25;17:1599-1610. Epub 2021 May 25.

Department of Psychiatry and Psychotherapy III, University of Ulm, Ulm, 89075, Germany.

Neurocysticercosis, the most common type of neuroparasitosis, is a condition in which the central nervous system (CNS) is infested with the pork tapeworm cysticercosis' larvae. Neurocysticercosis is the most widespread parasitic CNS disease worldwide, affecting more than 50 million individuals. As neurocysticercosis is prevalent in developing countries, the growing number of migrants and travelers increases prevalence in developed countries. Read More

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Neuroradiology of infectious diseases.

Curr Opin Infect Dis 2021 06;34(3):228-237

Section of Infectious Diseases, UT Health McGovern Medical School, Houston, Texas, USA.

Purpose Of Review: Early diagnosis of central nervous system (CNS) infections is crucial given high morbidity and mortality. Neuroimaging in CNS infections is widely used to aid in the diagnosis, treatment and to assess the response to antibiotic and neurosurgical interventions.

Recent Findings: The Infectious Diseases Society of America (IDSA) guidelines have clear recommendations for obtaining a computerized tomography of the head (CTH) prior to lumbar puncture (LP) in suspected meningitis. Read More

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Brain Infection in Pigs is Not Associated with Visible Lesions on Brain Magnetic Resonance Imaging.

Am J Trop Med Hyg 2020 07 14;103(1):273-275. Epub 2020 May 14.

3Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru.

Human exposure to spp. is very frequent, and its larvae can cross the blood-brain barrier and invade the central nervous system (CNS), causing neurotoxocariasis. We aimed to establish a neurotoxocariasis animal model in pigs confirmed by necropsy. Read More

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Saudi J Kidney Dis Transpl 2020 Jan-Feb;31(1):254-258

Department of Pharmacy Practice, Deccan School of Pharmacy, Hyderabad, Telangana, India.

Neurocysticercosis (NCC) is one of the common parasitic central nervous system (CNS) infections. Improperly cooked pork and eggs of the tapeworm Taenia solium, entering the body through the feco-oral route, are the common sources of its infection. Affected person may remain asymptomatic for long periods and can present with a variety of neurological manifestations, including focal neurological deficits and generalized seizures. Read More

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January 2021

First case of human neurocoenurosis caused by Taenia serialis: A case report.

Int J Infect Dis 2020 Mar 9;92:171-174. Epub 2020 Jan 9.

Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

Human coenurosis is caused by the larval stages of Taenia species, mainly Taenia multiceps and Taenia serialis. T. multiceps has been reported to cause human central nervous system (CNS) infections, but no CNS case caused by T. Read More

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Next generation sequencing based pathogen analysis in a patient with neurocysticercosis: a case report.

BMC Infect Dis 2018 03 6;18(1):113. Epub 2018 Mar 6.

Department of Neurology, First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou, 310003, China.

Background: Accurate and early diagnosis of neurocysticercosis (NCC) remains a challenge due to the heterogeneity of its clinical, immunological and imaging characteristics. The presence of cysticercus DNA in cerebrospinal fluid (CSF) of NCC patients has been previously detected via conventional PCR assays. To the best of our knowledge, the use of CSF Next-Generation Sequencing (NGS) based pathogen analysis in patients with NCC infection has never been reported. Read More

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[Intracranial cystic lesions].

Radiologe 2018 Feb;58(2):120-131

Klinik für Radiologie und Neuroradiologie, Universitätsklinikum Schleswig-Holstein, Kiel, Deutschland.

Clinical Problem: Intracerebral cysts are common findings in imaging of the neurocranium and are not always clinically significant. The pathological spectrum of intracerebral cysts is, however, very broad and in addition to incidental findings includes developmental disorders, malformation tumors, primary and secondary neoplasms and infectious etiologies, such as cerebral abscess formation, cysticercosis or residuals after congenital cytomegalovirus infections. Intracerebral cystic defects may be caused by inflammatory central nervous system (CNS) diseases, such as multiple sclerosis as well as by mitochondriopathies, leukodystrophy, electrolyte disturbances or osmotic demyelination syndrome or brain infarctions, e. Read More

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February 2018

Antibody Banding Patterns of the Enzyme-Linked Immunoelectrotransfer Blot and Brain Imaging Findings in Patients With Neurocysticercosis.

Clin Infect Dis 2018 01;66(2):282-288

School of Public Health and Management, Universidad Peruana Cayetano Heredia, Lima, Peru.

Background: The enzyme-linked immunoelectrotransfer blot (EITB) assay is the reference serological test for neurocysticercosis (NCC). A positive result on EITB does not always correlate with the presence of active infections in the central nervous system (CNS), and patients with a single viable brain cyst may be EITB negative. Nonetheless, EITB antibody banding patterns appears to be related with the expression of 3 protein families of Taenia solium, and in turn with the characteristics of NCC in the CNS (type, stage, and burden of viable cysts). Read More

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January 2018

Temporalis cysticerci - A diagnostic dilemma and review of literature.

J Stomatol Oral Maxillofac Surg 2017 Dec 8;118(6):371-375. Epub 2017 Jul 8.

Department of dental surgery, B.P.S Govt. Medical College for women, Khanpur kalan, 131305 Sonepat, Haryana, India.

Cysticercosis is a systemic parasitic infestation caused by ingesting the eggs of the pork tapeworm, Taenia solium. The central nervous system (CNS) is the most important primary site of infection and disease can present with solitary or multiple space-occupying lesion. Other organs like subcutaneous tissues, muscles, heart, liver, lungs, and peritoneum are more frequently affected but maxillofacial region involvement is rare. Read More

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December 2017

De novo cystic brain lesions mimicking neurocysticercosis in ALK-positive lung cancer.

Lung Cancer 2017 08 12;110:53-55. Epub 2017 Jun 12.

Center for Lung Cancer, Research Institute and Hospital of National Cancer Center, Goyang, Republic of Korea. Electronic address:

Cystic brain metastases (CBM) have been recently reported in a minority of patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC). All previously reported ALK-positive CBM developed during crizotinib treatment and were often asymptomatic and indolent, even without CNS-directed therapy. Thus, crizotinib was suggested as an etiologic agent for the development of CBM. Read More

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Time trend of neurocysticercosis in children with seizures in a tertiary hospital of western Nepal.

PLoS Negl Trop Dis 2017 May 10;11(5):e0005605. Epub 2017 May 10.

Dept of Pediatrics, Manipal Teaching Hospital, Pokhara, Nepal.

Introduction: Neurocysticercosis is a common cause of seizure disorders in children of Western Nepal. The clinical presentation is variable. The incidence varies depending on the food habits and ethnicity of the population. Read More

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Multiple calcifying pseudoneoplasms of the neuraxis (MCAPNON): Distinct entity, CAPNON variant, or old neurocysticercosis?

Neuropathology 2017 Jun 10;37(3):233-240. Epub 2016 Nov 10.

Department of Pathology and Laboratory Medicine (Neuropathology), University of California at Los Angeles, Los Angeles, CA, USA.

We report a case of multiple calcifying pseudoneoplasms of the neuraxis (MCAPNON) with associated multifocal perivascular microcalcifications and vascular calcinosis. Calcifying pseudoneoplasm of the neuraxis (CAPNON) is a very rare condition that may arise in extra-axial and occasionally, in intra-axial locations. Moreover, it is nearly always a solitary mass with only one case with two lesions reported. Read More

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Cysticercosis of Soleus muscle presenting as isolated calf pain.

J Clin Orthop Trauma 2015 Mar 1;6(1):39-41. Epub 2014 Dec 1.

Assistant Professor, Department of Radio-Diagnosis, Moti Lal Nehru Medical College, Allahabad, Uttar Pradesh, India.

CNS is the most common site of involvement by cysticercosis. Symptomatic involvement of isolated skeletal muscle by solitary cysticercosis cyst is extremely rare. We report a rare and unusual case of cysticercosis presenting as acute calf pain, which is a diagnostic challenge. Read More

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Reversible dementia due to neurocysticercosis: Improvement of the racemose type with antihistamines.

Dement Neuropsychol 2015 Jan-Mar;9(1):85-90

MD, PhD, Full Professor, Behavioral and Cognitive Neurology Unit, Department of Neurology Cognitive Disorders Reference Center (CEREDIC), HC/FMUSP, São Paulo SP, Brazil.

Infection of the human central nervous system (CNS) by the larvae of , termed neurocysticercosis (NCC), is endemic in most developing countries, where it is a major cause of acquired seizures and other neurological morbidity, including neuropsychiatric symptoms. However, despite its frequent manifestation, some findings, such as cognitive impairment and dementia, remain poorly understood. Less commonly, NCC may affect the ventricular system and subarachnoid spaces and this form is known as extraparenchymal neurocysticercosis. Read More

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December 2017

Parasitoses with central nervous system involvement.

Wien Med Wochenschr 2014 Oct 9;164(19-20):400-4. Epub 2014 Oct 9.

Krankenanstalt Rudolfstiftung, Juchgasse 25, 1030, Vienna, Austria,

Most of the parasitoses manifest systemically, including the central nervous system (CNS). Among the most prevalent parasitoses in Central Europe (cysticercosis, toxocarosis, echinococcosis, and toxoplasmosis), cerebral involvement is well recognized and part of the clinical presentation, which cannot be neglected. CNS involvement results from invasion of larvae of these parasites via the blood stream or by direct migration into the CNS. Read More

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October 2014

Immune responses to viable and degenerative metacestodes of Taenia solium in naturally infected swine.

Int J Parasitol 2013 Dec 31;43(14):1101-7. Epub 2013 Oct 31.

Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, UP, India.

Neurocysticercosis, caused by the larvae of the pork tapeworm Taenia solium, is the most common helminth infection of the CNS in humans worldwide. There is no existing animal model of neurocysticercosis that resembles human infection. To overcome this limitation, swine (the natural intermediate host of the parasite) may be a suitable model. Read More

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December 2013

Profile of children admitted with seizures in a tertiary care hospital of Western Nepal.

BMC Pediatr 2013 Mar 27;13:43. Epub 2013 Mar 27.

Department of Pediatrics, Manipal College of Medical Sciences, Pokhara, Nepal.

Background: Seizure is one of the common causes of childhood hospitalization with significant mortality and morbidity. There is limited data regarding acute seizures episodes form the developing countries. Current study aims to find the common etiology of seizure and classify seizure types in various age groups presenting to tertiary center in Western Nepal. Read More

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Continuum (Minneap Minn) 2012 Dec;18(6 Infectious Disease):1392-416

Air Center 3542, PO Box 522970, Miami, FL 33152-2970, USA.

Purpose Of Review: Neurocysticercosis occurs when humans become intermediate hosts in the life cycle of Taenia solium by ingesting its eggs directly from a taenia carrier or, less often, by contaminated food. Within the nervous system, cysticerci may lodge in the brain parenchyma, subarachnoid space, ventricular system, or spinal cord, causing a number of pathologic changes that are responsible for the pleomorphism of neurocysticercosis. This article discusses the clinical manifestations, diagnosis, and treatment of neurocysticercosis. Read More

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December 2012

Neurocysticercosis: the enigmatic disease.

Cent Nerv Syst Agents Med Chem 2011 Dec;11(4):261-84

Botucatu Medical School, São Paulo State University (UNESP), 18618-970, Botucatu, São Paulo, Brazil.

Neurocysticercosis (NCC) is an infection of the central nervous system (CNS) caused by the metacestode larval form of the parasite Taenia sp. Many factors can contribute to the endemic nature of cysticercosis. The inflammatory process that occurs in the tissue surrounding the parasite and/or distal from it can result from several associated mechanisms and may be disproportionate with the number of cysts. Read More

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December 2011

Spinal intramedullary cysticercosis: a case report and literature review.

Int J Med Sci 2011 6;8(5):420-3. Epub 2011 Jul 6.

Department of Neurosurgery, The First Hospital of Jilin University, Changchun 130021, China.

Neurocysticercosis, involvement of the central nervous system by taenia solium, is one of the most common parasitic diseases of the CNS. However, spinal involvement by neurocysticercosis is uncommon. Here, we reported a 40-year-old woman with intramedullary cysticercosis in the thoracic spinal cord. Read More

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October 2011

CT Ventriculography for diagnosis of occult ventricular cysticerci.

Surg Neurol Int 2010 Dec 23;1:92. Epub 2010 Dec 23.

Department of Neurosurgery, University of Illinois at Chicago, Chicago, IL 60612.

Background: Neurocysticercosis is the most common parasitic infection of the central nervous system (CNS). Intraventricular lesions are seen in 7-20% of CNS cysticercosis. Intraventricular lesions can be missed by computed tomography (CT) and magnetic resonance imaging (MRI) as they are typically isodense/isointense to the cerebrospinal fluid. Read More

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December 2010

Helminth infections of the central nervous system occurring in Southeast Asia and the Far East.

Adv Parasitol 2010 ;72:351-408

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People's Republic of China.

Although helminth infections of the central nervous system (CNS) are rare, their public health implications must not be neglected. Indeed, several helminth species can cause cerebrospinal infections, especially if humans serve as intermediate or non-permissive host. The diagnosis of cerebrospinal helminthiases is difficult, and the detection of parasites in cerebrospinal fluid is rarely successful. Read More

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October 2010

Cognitive impairment and dementia in neurocysticercosis: a cross-sectional controlled study.

Neurology 2010 Apr;74(16):1288-95

Department of Neurology, University of São Paulo School of Medicine, Brazil.

Objectives: Neurocysticercosis (NCYST) is the most frequent CNS parasitic disease worldwide, affecting more than 50 million people. However, some of its clinical findings, such as cognitive impairment and dementia, remain poorly characterized, with no controlled studies conducted so far. We investigated the frequency and the clinical profile of cognitive impairment and dementia in a sample of patients with NCYST in comparison with cognitively healthy controls (HC) and patients with cryptogenic epilepsy (CE). Read More

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Neurocysticercosis: relationship between Taenia antigen levels in CSF and MRI.

Arq Neuropsiquiatr 2010 Feb;68(1):7-11

Medicine Department, University of Taubaté, Taubaté, SP, Brazil.

Objective: To determine the relationship between Taenia antigen (TA) detection in cerebrospinal fluid (CSF) and magnetic resonance imaging (MRI) findings in patients with definite diagnosis of neurocysticercosis (NC).

Method: Sixty-three patients with definite diagnosis of NC were submitted to a MRI of the brain, and to a CSF examination, with a meticulous search for TA by ELISA.

Results: TA detection was positive in 36 patients (57. Read More

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February 2010

Isolated primary intradural extramedullary spinal neurocysticercosis: a case report and review of literature.

Acta Neurol Taiwan 2009 Sep;18(3):187-92

GTB Hospital, New Delhi.

Background: In spite of being the most common parasitic infestation of central nervous system (CNS), spinal cysticercosis remains a rare entity.

Case Report: We report an unusual case of a 45-year-old-male with primary isolated localization of spinal intradural extramedullary cysticercosis at thoracic 3/4 level. The lesion was surgically addressed to decompress the cord in combination with administration of oral albendazole. Read More

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September 2009

Cystic choroid plexus papilloma in the cavum septum pellucidum.

J Neurosurg Pediatr 2009 Dec;4(6):580-3

Department of Neurosurgery, New York University Langone Medical Center, New York, New York, USA.

A choroid plexus papilloma is a rare CNS neoplasm arising from the neuroepithelial lining of the choroid plexus. A third ventricular location of a choroid plexus papilloma is rare compared with the more common sites in the lateral and fourth ventricles. Cystic choroid plexus papilloma represents an infrequent subtype that may present diagnostic ambiguity. Read More

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December 2009