99 results match your criteria CNS Causes of Vertigo


Head-Shaking Nystagmus in Posterior Canal Benign Paroxysmal Positional Vertigo with Canalolithiasis.

J Clin Med 2021 Feb 26;10(5). Epub 2021 Feb 26.

Department of Neurology, School of Medicine, Keimyung University, Daegu 42601, Korea.

Background: There have been several studies about head-shaking nystagmus (HSN) in posterior canal benign paroxysmal positional vertigo (PC-BPPV). The purpose of the study was to determine the characteristics of HSN and its relationship with head-bending nystagmus (HBN) and lying-down nystagmus (LDN) in PC-BPPV and to suggest a possible pathomechanism of HSN based on these findings.

Methods: During the study period, 992 patients with BPPV were initially enrolled. Read More

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February 2021

Intracranial mass lesions and skin discoloration in the armpits as unusual clues to Erdheim-Chester disease: a case report.

BMC Neurol 2021 Feb 18;21(1):81. Epub 2021 Feb 18.

Division of Neurology, Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil.

Background: Erdheim-Chester disease (ECD) is a non-Langerhans histiocytosis that results in multi-organ disease involving the skin, bones, lungs and kidneys. Central nervous system (CNS) involvement occurs in about 50 % of patients, and diabetes insipidus, visual disturbances, and cerebellar ataxia are the most frequent neurological signs. We report a case of Erdheim-Chester disease with central nervous system involvement in the form of enhancing intracranial mass lesions with massive edema. Read More

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February 2021

Short-term efficacy and safety of lasmiditan, a novel 5-HT receptor agonist, for the acute treatment of migraine: a systematic review and meta-analysis.

J Headache Pain 2020 Jun 5;21(1):66. Epub 2020 Jun 5.

Department of Pharmacy, Daping Hospital, Army Medical University, Chongqing, 400042, P. R. China.

Background: Migraine has been recognized as one of common diseases in the world whose current treatment options are not ideal. Lasmiditan, an oral 5-hydroxytryptamine (HT) receptor agonist, appears more promising for the acute treatment of migraine because of considerably better effect profiles with no severe adverse events (AEs). This review aimed to systematically evaluate the efficacy and safety of lasmiditan from the results of randomized controlled trials (RCTs). Read More

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Upbeat vertical nystagmus after brain stem cavernoma resection: a rare case of nucleus intercalatus/nucleus of roller injury.

J Neurol 2020 Oct 26;267(10):2865-2870. Epub 2020 May 26.

UMR 1253, iBrain, Université de Tours, Inserm, Tours, France.

Introduction: CNS cavernomas are a type of raspberry-shaped vascular malformations that are typically asymptomatic, but can result in haemorrhage, neurological injury, and seizures. Here, we present a rare case of a brainstem cavernoma that was surgically resected whereafter an upbeat nystagmus presented postoperatively.

Case Report: A 42-year old man presented with sudden-onset nausea, vomiting, vertigo, blurred vision, marked imbalance and difficulty swallowing. Read More

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October 2020

Safety and clinical effectiveness of Withania Somnifera (Linn.) Dunal root in human ailments.

J Ethnopharmacol 2020 Jun 19;255:112768. Epub 2020 Mar 19.

Indian Council of Medical Research, Ansari Nagar, New Delhi, India.

Ethnopharmacological Relevance: Withania somnifera popularly known as Aswagandha or Indian Ginseng/Poison Gooseberry have thousands years of history of use in Indian traditional medicine. Besides, finding place root of the plant as Indian Ginseng, Ayurveda also uses root of this plant as general health tonic, adaptogenic, nootropic, immunomodulatory etc. With its widespread and growing use, it becomes prudent to scientifically evaluate and document both the efficacy and safety of this plant in humans. Read More

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Central Conditions Mimicking Benign Paroxysmal Positional Vertigo: A Case Series.

J Neurol Phys Ther 2019 07;43(3):186-191

Balance Disorders and Ataxia Service, The Royal Victorian Eye and Ear Hospital, Melbourne, Australia (L.P., D.J.S.); Florey Institute of Neuroscience and Mental Health, Melbourne, Australia (L.P., D.J.S.); Dizzy Day Clinics, Melbourne, Australia (L.P., K.M.); Department of Neurosurgery (K.B.) and Medical Imaging Department (N.T.), St Vincents Hospital, Melbourne, Australia; Department of Neurosurgery, Royal Melbourne Hospital, and Department of Surgery, University of Melbourne, Australia (K.J.D.); and Neuroscience Department, Cerebellar Ataxia Clinic, Alfred Health, Melbourne, Australia (D.J.S.).

Background And Purpose: Benign paroxysmal positional vertigo (BPPV) is the most common cause of positional vertigo. The term "benign" is consistent with a peripheral vestibular disorder that does not carry the potentially sinister sequelae of a central nervous system (CNS) cause. However, in 12% to 20% of cases, positional vertigo may be attributed to CNS pathology, including tumors of the cerebellum. Read More

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Wegener's Granulomatosis Presenting as Wallenberg Syndrome: A Case Report.

J Stroke Cerebrovasc Dis 2019 Aug 23;28(8):e107-e109. Epub 2019 Apr 23.

Department of internal madicine, Rasool-e Akram hospital, Iran University of Medical Sciences, Tehran, Iran.

Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis, a vasculitis affecting small and medium sized vessels usually affects the upper and lower respiratory tract, the kidneys, and the eyes. Neurologic manifestation in central nervous system (CNS) is less frequent than the peripheral and usually is in form of stroke. Few cases of lateral medullary ischemic stroke (Wallenberg syndrome) due to GPA have been reported. Read More

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Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) in limited cutaneous sclerosis: a rare disease combination.

BMJ Case Rep 2019 Jan 7;12(1). Epub 2019 Jan 7.

Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

A 26-year-old patient of limited cutaneous sclerosis presented to us with insidious-onset posterior fossa symptoms of headache, vomiting, vertigo and gait imbalance, progressing over a period of 3 weeks. A diagnosis of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids was made by combining the clinical features with radiological evidence showing punctate infiltration of the pons, brainstem and cerebellum. Relevant differentials in the form of neurosarcoid, infections, central nervous system (CNS) lymphoma and Neuro-Behcet's disease were ruled out by history and investigations. Read More

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January 2019

Autoimmune encephalitis with elevated N-type calcium channel antibodies as a multiple sclerosis mimic.

Mult Scler Relat Disord 2018 Nov 25;26:201-203. Epub 2018 Sep 25.

Department of Neurology, West Virginia University, 1 Medical Center Drive, Morgantown, WV 26505, USA.

Background: Voltage gated calcium channels (VGCC) are well-known targets for antibody-associated disease. Of the 5 VGCC subtypes, the most well-known is the P/Q subtype associated with Lambert-Eaton Myasthenic Syndrome (LEMS). However, this case focuses on the much less understood N-type calcium channel antibody. Read More

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November 2018

Trichosporon inkin meningitis in Northeast Brazil: first case report and review of the literature.

BMC Infect Dis 2018 Sep 18;18(1):470. Epub 2018 Sep 18.

Centro de Ciências da Saúde, Laboratório de Micologia Médica e Molecular, Departamento de Análises Clínicas e Toxicológicas, Universidade Federal do Rio Grande do Norte, Rua Gal. Gustavo Cordeiro de Faria S/N, Petrópolis, Natal, Rio Grande do Norte, Brazil.

Background: Trichosporon species may colonize the skin, respiratory tract and gastrointestinal tract of human beings. The yeast is recognized as etiological agent of white piedra, a superficial mycosis. Nevertheless, immunocompromised hosts may develop invasive Trichosporonosis. Read More

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September 2018

Elevated visual dependency in young adults after chemotherapy in childhood.

PLoS One 2018 21;13(2):e0193075. Epub 2018 Feb 21.

Department of Pediatrics, Skåne University Hospital, Lund, Sweden.

Chemotherapy in childhood can result in long-term neurophysiological side-effects, which could extend to visual processing, specifically the degree to which a person relies on vision to determine vertical and horizontal (visual dependency). We investigated whether adults treated with chemotherapy in childhood experience elevated visual dependency compared to controls and whether any difference is associated with the age at which subjects were treated. Visual dependency was measured in 23 subjects (mean age 25. Read More

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Review of the Neurological Implications of von Hippel-Lindau Disease.

JAMA Neurol 2018 05;75(5):620-627

Department of Neurological Surgery, The Ohio State University Wexner Medical Center, Columbus.

Importance: von Hippel-Lindau (VHL) disease-associated central nervous system (CNS) lesions include hemangioblastomas and endolymphatic sac tumors (ELSTs), which are associated with significant neurological morbidity and mortality. Recent studies provide critical new biological, diagnostic, and management insights into these tumors.

Observations: Biological features, natural history, clinical findings, and management strategies of VHL disease-associated CNS tumors are reviewed. Read More

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Parasympathetic nervous system involvement in food allergy: description of a paediatric case.

J Biol Regul Homeost Agents 2016 Oct-Dec;30(4):1137-1140

Paediatric Operative Unit and Acute and Emergency, Vittorio-Emanuele University Hospital, University of Catania, Italy.

The latest research data emphasize the interaction between the nervous and the immune systems. It has been demonstrated that the central nervous system (CNS) can be involved secondarily due to blood brain barrier (BBB) disruption via pro-inflammatory cytokines released in allergy. More recently it was demonstrated that the parasympathetic nervous system (PNS) could also be equally involved in models of peripheral inflammation such as food allergy; although this last clinical presentation has rarely been described. Read More

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Subcutaneous melanocytoma mimicking a lipoma: a rare presentation of a rare neoplasm with histological, immunohistochemical, cytogenetic and molecular characterization.

J Cutan Pathol 2016 Dec 27;43(12):1186-1196. Epub 2016 Sep 27.

Department of Pathology, Saint Louis University School of Medicine, St. Louis, MO, USA.

Melanocytoma are the melanocytic tumors originating from leptomeningeal melanocytes. Melanocytomas are commonly seen in the central nervous system (CNS) and are often associated with neurocutaneous melanosis (NCM). However, simultaneous presentation of intra-axial and extracranial melanocytoma is a very rare event. Read More

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December 2016

Stroke risk stratification in acute dizziness presentations: A prospective imaging-based study.

Neurology 2015 Nov 28;85(21):1869-78. Epub 2015 Oct 28.

From the Stroke Program (K.A.K., W.J.M., D.L.B., J.F.B., E.E.A., L.B.M.) and Departments of Neurology (K.A.K., W.J.M., D.L.B., J.F.B., E.E.A., L.B.M.), Emergency Medicine (W.J.M.), Internal Medicine (T.P.H., A.M.F.), and Radiology (E.G.H.), University of Michigan Health System, Ann Arbor; and Department of Biostatistics (A.T.), University of Michigan School of Public Health, Ann Arbor.

Objective: To estimate the ability of bedside information to risk stratify stroke in acute dizziness presentations.

Methods: Surveillance methods were used to identify patients with acute dizziness and nystagmus or imbalance, excluding those with benign paroxysmal positional vertigo, medical causes, or moderate to severe neurologic deficits. Stroke was defined as acute infarction or intracerebral hemorrhage on a clinical or research MRI performed within 14 days of dizziness onset. Read More

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November 2015

Posterior fossa mass in immunosuppressed patient.

Bull Soc Sci Med Grand Duche Luxemb 2014 (3):25-30

Centre Hospitalier de Luxembourg.

Background: Toxoplasmosis is the most frequent opportunistic infection of the central nervous system among individuals with the acquired immunodeficiency syndrome. Radiographic modalities include brain CT, MRI and PET scan. The differential diagnosis are usually: primary CNS lymphoma, cerebral metastasis, Progressive multifocal leukoencephalopathy, cytomegalovirus. Read More

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February 2015

CNS-disease affecting the heart: brain-heart disorders.

J Neurol Sci 2014 Oct 8;345(1-2):8-14. Epub 2014 Jul 8.

Paris-Descartes, Sorbonne Paris Cite University, 75006 Paris, France; AP-HP, Cardiology Department, Cochin Hospital, Paris, France; AP-HP, Pitié-Salpêtrière Hospital, Neurology Department, Paris, France.

There are a number of hereditary and non-hereditary central nervous system (CNS) disorders, which directly or indirectly affect the heart (brain-heart disorders). The most well-known of these CNS-disorders are epilepsy, stroke, subarachanoid bleeding, bacterial meningitis, and head injury. In addition, a number of hereditary and non-hereditary neurodegenerative disorders may impair cardiac functions. Read More

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October 2014

Paraneoplastic neuromyelitis optica spectrum disorder associated with stomach carcinoid tumor.

Hematol Oncol Stem Cell Ther 2014 Sep 20;7(3):116-9. Epub 2014 Jun 20.

King Khalid Medical City for Human Health Research, King Fahad Specialist Hospital, 6830 Ammar Bin Thabit St, Al Muraikabat, Dammam 32253-3202, Saudi Arabia.

Neuromyelitis optica (NMO), or Devic's syndrome, is an autoimmune central nervous system demyelinating disorder primarily affecting the spinal cord and the optic nerves. It is characterized by the presence of NMO antibodies, alongside clinical and radiological findings. NMO and NMO-spectrum disorders (NMO-SD) have been reported in autoimmune disorders, and are infrequently described as a paraneoplastic syndrome with cancers of lung, breast, and carcinoid tumors of the thyroid. Read More

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September 2014

Primary EBV-positive Hodgkin's lymphoma of the CNS under azathioprine treatment: case report and review of the literature.

Strahlenther Onkol 2014 Sep 14;190(9):847-52. Epub 2014 May 14.

Klinik für Strahlentherapie und Spezielle Onkologie, Medizinische Hochschule Hannover, Hannover, Germany.

Background: Retrospective and prospective cohort studies suggest that central nervous system involvement occurs in approximately 0.5% of patients with advanced Hodgkin's lymphoma. The isolated primary intracranial manifestation of Hodgkin's lymphoma is an extremely rare finding, with few cases reported in the literature. Read More

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September 2014

Neurology and diving.

Handb Clin Neurol 2014 ;120:959-69

Departments of Anesthesiology and Medicine, Duke University Medical Center, Durham, NC, USA.

Diving exposes a person to the combined effects of increased ambient pressure and immersion. The reduction in pressure when surfacing can precipitate decompression sickness (DCS), caused by bubble formation within tissues due to inert gas supersaturation. Arterial gas embolism (AGE) can also occur due to pulmonary barotrauma as a result of breath holding during ascent or gas trapping due to disease, causing lung hyperexpansion, rupture and direct entry of alveolar gas into the blood. Read More

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Nonsteroidal anti-inflammatory drugs exposure and the central nervous system.

Handb Clin Neurol 2014 ;119:577-84

Department of Neurology, Tel-Aviv University, Ramat-Aviv, Israel. Electronic address:

Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used agents in clinical practice. They are employed as anti-inflammatory, analgesic, and antipyretic agents for a wide spectrum of clinical conditions. Their anti-inflammatory properties are primarily due to inhibition of prostaglandin synthesis. Read More

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GABA-B-receptor antibodies in paraneoplastic brainstem encephalitis.

J Neuroimmunol 2013 Jun 28;259(1-2):88-91. Epub 2013 Apr 28.

Department of Neurology, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.

Background: Gamma-aminobutyric-acid B (GABA-B)-receptor encephalitis represents a novel entity among autoimmune CNS disorders. Most cases are characterised by limbic encephalitis.

Case Report: A 63-year-old patient presented with acute vertigo, nausea and vomiting, facial palsy and dysarthria. Read More

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A 63 year old woman with white matter lesions and pachymeningeal inflammation.

Brain Pathol 2013 Mar;23(2):225-8

Neurological Institute of New York, Columbia University Medical Center, New York, NY, USA.

We describe the case of a 63-year-old woman with CNS Rosai-Dorfman disease, presenting with diffuse dural infiltration, mimicking idiopathic hypertrophic pachymeningitis, and right vertebral artery dissection. Her symptoms included a progressive 11-month history of vertigo, gait ataxia, and right thalamic stroke. A diagnosis of CNS Rosai-Dorfman disease was made following open dural biopsy, and later confirmed on autopsy studies. Read More

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Management of vestibular schwannoma: focus on vertigo.

CNS Oncol 2013 Jan;2(1):99-104

Department of Radiation Oncology, University of California at San Francisco, 505 Parnassus Avenue, Room L-08 (Box 0226), San Francisco, CA 94143-0226, USA.

This article reviews published literature on vertigo and a 'sense of imbalance' affecting patients who are treated with radiosurgery (RS) for vestibular schwannoma. This is a relatively understudied complaint, along with tinnitus, in this patient population, despite its significant impact on quality of life. It is also a symptom that is most inconsistently impacted by either RS or surgery. Read More

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January 2013

Rate and predictors of serious neurologic causes of dizziness in the emergency department.

Mayo Clin Proc 2012 Nov 12;87(11):1080-8. Epub 2012 Oct 12.

Department of Neurology and Neuroscience, Weill Cornell Medical College, New York, NY, USA.

Objective: To describe the rate and predictors of central nervous system (CNS) disease in emergency department (ED) patients with dizziness in the modern era of neuroimaging.

Patients And Methods: We retrospectively reviewed the medical records of all adults presenting between January 1, 2007, and December 31, 2009, to an academic ED for a primary triage complaint of dizziness, vertigo, or imbalance. The final diagnosis for the cause of dizziness was independently assigned by 2 neurologists, with a third neurologist resolving any disagreements. Read More

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November 2012

Positional dizziness.

Authors:
Terry D Fife

Continuum (Minneap Minn) 2012 Oct;18(5 Neuro-otology):1060-85

Barrow Neurological Institute, 240 West Thomas Road, Suite 301, Phoenix, Arizona 85013, USA.

Purpose: This article reviews the most common conditions that are caused by changes in head or body positions. Practical clinical methods to help distinguish vestibular from nonvestibular and central from peripheral vestibular positional dizziness are discussed. This article also reviews the treatment methods of selected canal variants of benign paroxysmal positional vertigo (BPPV). Read More

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October 2012

Primary cerebellopontine angle melanoma: a case report and review.

Turk Neurosurg 2012 ;22(4):469-74

Calicut Medical College, Department of General Surgery, Calicut, India.

Primary melanomas at the cerebellopontine (CP) angle are extremely rare and considered a diagnostic dilemma. With only 16 prior cases reported so far, there is not enough material in world literature. We report a 29-year-old male who presented with vertigo, headache and features of lower cranial nerve involvement with MRI revealing a melanotic lesion at CP angle. Read More

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December 2012

Solitary fibrous tumor of the tentorium: a case report.

Turk Neurosurg 2012 ;22(4):454-7

Government Medical College, Department of Neurosurgery, Kerala, India.

The authors describe the clinical and pathological features of a solitary fibrous tumor of the tentorium, a rare location for the tumor in the CNS. A 52-year-old lady presented to the neurosurgical services with headache of four months and vertigo of one and a half months duration. On examination, she had left-sided cerebellar signs and bilateral papilloedema. Read More

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December 2012