13,119 results match your criteria CIN: Computers Informatics Nursing[Journal]


Curative-intent radiotherapy for pediatric osteosarcoma: The St. Jude experience.

Pediatr Blood Cancer 2019 Apr 22:e27763. Epub 2019 Apr 22.

Departments of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.

Background: Radiation therapy (RT) confers local tumor control and survival advantages in some patients with osteosarcoma, yet pediatric and adolescent and young adult (AYA) population studies are limited.

Methods: Twenty-eight patients treated with curative-intent RT (median dose, 59.4 Gy; range, 40-76 Gy) at our institution from 1990 to 2017 were retrospectively identified. Read More

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http://dx.doi.org/10.1002/pbc.27763DOI Listing

A Survey of Nurses' Need for Care Robots in Children's Hospitals: Combining Robot-Care, Game-Care, and Edu-Care.

Comput Inform Nurs 2019 Apr 19. Epub 2019 Apr 19.

Author Affiliations: College of Nursing, Consumer Health Informatics & Communication Laboratory (Ms Jin and Dr Kim), Research Institute of Nursing Science (Dr Kim), Seoul National University, Seoul, Republic of Korea.

The purpose of this study was to investigate nurses' need for care robots in children's hospitals and to help develop care robots that can be used by combining robot-care, game-care, and edu-care. This study employed a mixed-methods design; 198 nurses were recruited for quantitative research and 12 for qualitative research. The findings were as follows. Read More

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http://dx.doi.org/10.1097/CIN.0000000000000527DOI Listing
April 2019
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[Effects of hnRNP E1 and both early genes E2 and E6 of HPV16 together with their interactions on cervical carcinogenesis].

Zhonghua Liu Xing Bing Xue Za Zhi 2019 Apr;40(4):466-470

Department of Epidemiology, School of Public Health, Shanxi Medical University, Taiyuan 030001, China.

To explore the effects of hnRNP E1 and both early genes E2 and E6 of HPV16 as well as their interactions in the progression of cervical carcinogenesis. Subjects of this study included 56 women with normal cervix (NC), 58 patients with low-grade cervical intraepithelial neoplasm (CINⅠ) and 50 patients with high-grade cervical intraepithelial neoplasm (CINⅡ/Ⅲ) who were all recruited from the 'Cervical Lesions Study Cohort Project' in Jiexiu of Shanxi province from June to September, 2014. Another 40 patients with cervical squamous cell carcinoma (SCC) were from the Shanxi Tumor Hospital during the same period. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0254-6450.2019.04.018DOI Listing

Risk of contrast-induced nephropathy in patients undergoing complex percutaneous coronary intervention.

Int J Cardiol 2019 Apr 14. Epub 2019 Apr 14.

Interventional Cardiology Division, Cardio-Thoracic-Vascular Department, San Raffaele Scientific Institute, Milan, Italy.

Background: Complex percutaneous coronary intervention (PCI) is associated with increased procedural challenges and high contrast load. We aimed to evaluate the association between complex PCI and contrast-induced nephropathy (CIN).

Methods: This single-center retrospective study included all-comers undergoing PCI between January 2012 and December 2016. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01675273193147
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http://dx.doi.org/10.1016/j.ijcard.2019.04.043DOI Listing
April 2019
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Treatment patterns and disease outcomes for pediatric patients with refractory or recurrent Hodgkin lymphoma treated with curative-intent salvage radiotherapy.

Radiother Oncol 2019 May 5;134:89-95. Epub 2019 Feb 5.

Department of Radiation Oncology, St. Jude Children's Hospital, Memphis, United States.

Background And Purpose: The use of radiotherapy (RT) for pediatric patients with Hodgkin lymphoma (HL) experiencing disease progression or recurrence (15%) is controversial. We report treatment patterns and outcomes for pediatric patients with refractory/recurrent HL (rrHL) treated with curative-intent RT.

Materials And Methods: Forty-six patients with rrHL treated with salvage RT at our institution were identified. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01678140193005
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http://dx.doi.org/10.1016/j.radonc.2019.01.026DOI Listing
May 2019
1 Read

Over Expressed TKTL1, CIP-2A, and B-MYB Proteins in Uterine Cervix Epithelium Scrapings as Potential Risk Predictive Biomarkers in HR-HPV-Infected LSIL/ASCUS Patients.

Front Oncol 2019 3;9:213. Epub 2019 Apr 3.

Human Histology and Embryology Unit, University of Verona Medical School, Verona, Italy.

High oncogenic risk human papillomaviruses (HR-HPVs) promote cervical carcinoma development, the fourth most common feminine cancer. A slow oncodevelopmental phase-defined histopathologically as Cervical Intraepithelial Neoplasia (CIN) grades 1-3, or cytologically as Low- or High-grade Squamous Intraepithelial Lesions (LSIL or HSIL)-precedes the malignancy. Cervical carcinoma screenings through HR-HPV genotyping and Pap smears are regularly performed in Western countries. Read More

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http://dx.doi.org/10.3389/fonc.2019.00213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456695PMC

Hybrid Degradation Equipment Remaining Useful Life Prediction Oriented Parallel Simulation considering Model Soft Switch.

Comput Intell Neurosci 2019 12;2019:9179870. Epub 2019 Mar 12.

Shijiazhuang Campus, Army Engineering University, Shijiazhuang 050003, China.

Equipment parallel simulation is an emerging simulation technology in recent years, and equipment remaining useful life (RUL) prediction oriented parallel simulation is an important branch of parallel simulation. An important concept in equipment parallel simulation is the model evolution driven by real-time data, including model selection and model parameter evolution. The current research on equipment RUL prediction oriented parallel simulation mainly focuses on a single continuous degradation mode, such as linear degradation and nonlinear degradation. Read More

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http://dx.doi.org/10.1155/2019/9179870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434305PMC
March 2019
1 Read

HPV16 variant analysis in primary and recurrent CIN2/3 lesions demonstrates presence of the same consensus variant.

Papillomavirus Res 2019 Apr 13;7:168-172. Epub 2019 Apr 13.

Amsterdam UMC, Vrije Universiteit, Department of Pathology, Cancer Center Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands. Electronic address:

Introduction: Recurrent cervical intraepithelial lesions (rCIN2/3) after treatment of CIN2/3 occur in 5-15% of cases. rCIN2/3 can result from incomplete resection of CIN2/3, where the same HPV type and variant remains present. rCIN2/3 could also occur following a new infection with a different HPV variant of the same HPV type as the initial lesion. Read More

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http://dx.doi.org/10.1016/j.pvr.2019.04.008DOI Listing

Efficacy and safety of endovascular therapy by diluted contrast digital subtraction angiography in patients with chronic kidney disease.

Heart Vessels 2019 Apr 15. Epub 2019 Apr 15.

Department of Cardiovascular Medicine, Asahi General Hospital, I-1326 Asahi, Chiba, 289-2511, Japan.

This study was performed to evaluate the efficacy and safety of endovascular therapy (EVT) by diluted contrast digital subtraction angiography (DSA) in patients with chronic kidney disease (CKD). Patients with peripheral artery disease (PAD) often have CKD; thus, EVT carries a risk of contrast-induced nephropathy (CIN). Reducing the amount of contrast medium is, therefore, important in these patients. Read More

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http://dx.doi.org/10.1007/s00380-019-01412-2DOI Listing

Preventive Effects of Nicorandil Against Contrast-Induced Nephropathy in Patients With Moderate Renal Insufficiency Undergoing Percutaneous Coronary Intervention.

Angiology 2019 Apr 15:3319719841733. Epub 2019 Apr 15.

2 Department of Cardiology, Tianjin Chest Hospital, Tianjin, China.

We investigated the preventive effect of nicorandil on contrast-induced nephropathy (CIN) in patients with moderate renal insufficiency undergoing percutaneous coronary intervention (PCI). A total of 250 patients with a creatinine clearance (crCl) ≤60 mL/min undergoing PCI were randomly assigned to either a nicorandil group (nicorandil 10 mg 3 times/d and hydration; n = 125) or a control group (hydration only; n = 125). The first end point was the incidence of CIN defined as an increase in serum creatinine (Scr) levels by ≥0. Read More

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http://dx.doi.org/10.1177/0003319719841733DOI Listing
April 2019
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Identification of -Oxide-Containing Aromatic Heterocycles as Pharmacophores for Rumen Fermentation Modifiers.

Metabolites 2019 Apr 2;9(4). Epub 2019 Apr 2.

Grupo de Química Medicinal, Laboratorio de Química Orgánica Medicinal, Instituto de Química Biológica, Facultad de Ciencias, Universidad de la República, Iguá 4225, Montevideo 11400, Uruguay.

Different strategies have been used to mitigate greenhouse gas emissions from domesticated ruminants, including the removal of protozoa (defaunation). The objective of the present work was to analyze the potential of different -oxide-containing aromatic heterocycles with known antiprotozoal activity as rumen-gas-abating agents. Nineteen pure compounds, belonging to seven different -oxide chemotypes from our chemo-library were studied together with monensin in an in vitro rumen simulation assay. Read More

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http://dx.doi.org/10.3390/metabo9040062DOI Listing

HPV infection and pre-term birth: a data-linkage study using Scottish Health Data.

Wellcome Open Res 2019 8;4:48. Epub 2019 Mar 8.

Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, EH16 4UX, UK.

We aimed to investigate whether infection with high-risk (HR) types of human papilloma virus (HPV) or HPV-associated cervical disease were associated with preterm birth (<37 weeks gestation). In a sub-group of younger women who were eligible for the HPV vaccine, we aimed to determine whether prior vaccination against the specific HPV-types, HPV-16 and -18 modified preterm birth risk. This was a data-linkage study, which linked HPV-associated viral and pathological information (from the Scottish HPV Archive) from women aged 16-45 years to routinely collected NHS maternity- and hospital-admission records from 1999-2015. Read More

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https://wellcomeopenresearch.org/articles/4-48/v1
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http://dx.doi.org/10.12688/wellcomeopenres.15140.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436145PMC
March 2019
4 Reads

Optimal Operation of the Hybrid Electricity Generation System Using Multiverse Optimization Algorithm.

Comput Intell Neurosci 2019 11;2019:6192980. Epub 2019 Mar 11.

Department of Computer Science, Abdul Wali Khan University Mardan, Mardan, KP, Pakistan.

The ongoing load-shedding and energy crises due to mismanagement of energy produced by different sources in Pakistan and increasing dependency on those sources which produce energy using expensive fuels have contributed to rise in load shedding and price of energy per kilo watt hour. In this paper, we have presented the linear programming model of 95 energy production systems in Pakistan. An improved multiverse optimizer is implemented to generate a dataset of 100000 different solutions, which are suggesting to fulfill the overall demand of energy in the country ranging from 9587 MW to 27208 MW. Read More

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https://www.hindawi.com/journals/cin/2019/6192980/
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http://dx.doi.org/10.1155/2019/6192980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432705PMC
March 2019
1 Read

Nine-valent HPV vaccine efficacy against related diseases and definitive therapy: comparison with historic placebo population.

Gynecol Oncol 2019 Apr 11. Epub 2019 Apr 11.

Merck & Co., Inc., Kenilworth, NJ, United States. Electronic address:

Objective: Nine-valent human papillomavirus (9vHPV) vaccine efficacy against disease and cervical surgeries related to all nine vaccine components was assessed compared with a historic placebo population. This was not assessed in the 9vHPV vaccine efficacy trial since the trial was quadrivalent HPV (qHPV) vaccine-controlled, efficacy was measured for the five HPV types covered only by 9vHPV vaccine (HPV31/33/45/52/58), but not the four types covered by both vaccines (HPV6/11/16/18).

Methods: Three international, randomized, double-blind studies were conducted using the same methodology. Read More

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http://dx.doi.org/10.1016/j.ygyno.2019.03.253DOI Listing
April 2019
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Cervical Adenocarcinoma in Situ: Human Papillomavirus Types and Incidence Trends in Five States, 2008-2015.

Int J Cancer 2019 Apr 13. Epub 2019 Apr 13.

Centers for Disease Control and Prevention, Atlanta, Georgia, United States.

Primary prevention through the use of human papillomavirus (HPV) vaccination is expected to impact both cervical intraepithelial neoplasia (CIN) and adenocarcinoma in situ (AIS). While CIN is well described, less is known about the epidemiology of AIS, a rare cervical precancer. We identified AIS and CIN grade 3 (CIN3) cases through population-based surveillance, and analyzed data on HPV types and incidence trends overall, and among women screened for cervical cancer. Read More

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http://dx.doi.org/10.1002/ijc.32340DOI Listing

Octamer binding transcription factor-4 expression is associated with cervical cancer malignancy and histological differentiation: A systematic review and meta-analysis.

Biosci Rep 2019 Apr 12. Epub 2019 Apr 12.

Department of Gastroenterology, Taihe Hospital, Shiyan, Washington, 442012, China

Objective: The relationship between the expression of octamer binding transcription factor 4  (OCT-4) and clinicopathological features of cervical cancer (CC) is evaluated in detail.

Methods: The findings on the relationship collected by retrieving PubMed, EMBASE, Cochrane library, Wan Fang and Chinese National Knowledge Infrastructure(CNKI) databases results and tracing back to the literature and published in public, which began in setting up the literature database and ended in May 2018. The literatures are screened, extracted and evaluated according to the inclusion and exclusion criteria, and meta-analysis was carried out via RevMan 5. Read More

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http://bioscirep.org/lookup/doi/10.1042/BSR20182328
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http://dx.doi.org/10.1042/BSR20182328DOI Listing
April 2019
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Development and evaluation of a cervical cancer screening system in Cambodia: A collaborative project of the Cambodian Society of Gynecology and Obstetrics and Japan Society of Obstetrics and Gynecology.

J Obstet Gynaecol Res 2019 Apr 11. Epub 2019 Apr 11.

Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan.

Aim: In Cambodia, the Japan Society of Obstetrics and Gynecology and the Cambodian Society of Gynecology and Obstetrics have an on-going project, started in 2015, for cervical cancer prevention and treatment. The project, currently aimed at factory workers, includes a women's health education program that leads into cervical cancer prevention by establishment of a system for early detection and treatment. It begins by health education, screening for human papillomavirus (HPV), followed by colposcopy and quicker treatment of earlier precursor lesions. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jog.13968
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http://dx.doi.org/10.1111/jog.13968DOI Listing
April 2019
3 Reads

Angioplasty with Stenting in Acute Coronary Syndromes with Very Low Contrast Volume Using 6F Diagnostic Catheters and Bench Testing of Catheters.

Open Access Maced J Med Sci 2019 Mar 29;7(6):1004-1012. Epub 2019 Mar 29.

Pondicherry Institute of Medical Sciences, Kalapet, India.

Aim: To safely perform angioplasties in acute coronary syndromes with low contrast volume using Cordis 6F diagnostic catheters and to perform mechanical bench tests on the diagnostic and guide catheters in a radial path model.

Methods: In 191 patients (242 lesions/268 stents) with acute coronary syndromes angioplasty were performed with cordis 6F diagnostic catheters.

Results: The lesions were present at left anterior descending (121), Left main (5), left circumflex (51), ramus (5) and right coronary artery (60). Read More

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http://dx.doi.org/10.3889/oamjms.2019.238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454170PMC
March 2019
1 Read

LC/MS-Based Polar Metabolite Profiling Identified Unique Biomarker Signatures for Cervical Cancer and Cervical Intraepithelial Neoplasia Using Global and Targeted Metabolomics.

Cancers (Basel) 2019 Apr 10;11(4). Epub 2019 Apr 10.

Division of Cancer Epidemiology and Prevention, National Cancer Center, Madu-dong, Ilsandong-gu, Goyang-si, Gyeonggi-do 10408, Korea.

Cervical cancer remains one of the most prevalent cancers among females worldwide. Therefore, it is important to discover new biomarkers for early diagnosis of cervical intraepithelial neoplasia (CIN) and cervical cancer, preferably non-invasive ones. In the present study, we aimed to identify unique metabolic signatures for CINs and cervical cancers using global and targeted metabolomic profiling. Read More

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https://www.mdpi.com/2072-6694/11/4/511
Publisher Site
http://dx.doi.org/10.3390/cancers11040511DOI Listing
April 2019
5 Reads

Treatment patterns and outcomes in patients with non-small cell lung cancer receiving biosimilar filgrastim for prophylaxis of chemotherapy-induced/febrile neutropaenia: Results from the MONITOR-GCSF study.

Eur J Cancer Care (Engl) 2019 Apr 10:e13034. Epub 2019 Apr 10.

Division of Medical Oncology, Department of Hematology-Oncology, Hospital Clínic de Barcelona, University of Barcelona, Barcelona, Spain.

Objective: Real-world evidence data on the use of granulocyte colony-stimulating factor (G-CSF) in patients with non-small cell lung cancer (NSCLC) are limited. MONITOR-GCSF is a pan-European, multicentre, prospective, non-interventional study designed to describe patient characteristics, treatment patterns and clinical outcomes in patients receiving biosimilar filgrastim in the prophylaxis of chemotherapy-induced neutropaenia (CIN) and febrile neutropaenia (FN).

Methods: In this subanalysis, patient characteristics, treatment patterns, and outcomes are described for 345 patients with stage 3 or 4 NSCLC, receiving up to six chemotherapy cycles. Read More

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http://dx.doi.org/10.1111/ecc.13034DOI Listing
April 2019
3 Reads

Modifying an Active Compound's Release Kinetic Using a Supercritical Impregnation Process to Incorporate an Active Agent into PLA Electrospun Mats.

Polymers (Basel) 2018 Apr 27;10(5). Epub 2018 Apr 27.

Laboratory of Membrane Separation Processes (LabProSeM), Department of Chemical Engineering, Engineering Faculty, University of Santiago de Chile (USACH), 9170201 Santiago, Chile.

The main objective of this work was to study the release of cinnamaldehyde (CIN) from electrospun poly lactic acid (PLA) mats obtained through two techniques: (i) direct incorporation of active compound during the electrospinning process (PLA-CIN); and (ii) supercritical carbon dioxide (scCO₂) impregnation of CIN within electrospun PLA mats (PLA/CIN). The development and characterization of both of these active electrospun mats were investigated with the main purpose of modifying the release kinetic of this active compound. Morphological, structural, and thermal properties of these materials were also studied, and control mats PLA and PLA CO 2 were developed in order to understand the effect of electrospinning and scCO₂ impregnation, respectively, on PLA properties. Read More

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http://dx.doi.org/10.3390/polym10050479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415505PMC

Effects of intravenous hydration on risk of contrast induced nephropathy and in-hospital mortality in STEMI patients undergoing primary percutaneous coronary intervention: a systematic review and meta-analysis of randomized controlled trials.

BMC Cardiovasc Disord 2019 Apr 8;19(1):87. Epub 2019 Apr 8.

The George Institute for Global Health, the University of Sydney, Camperdown, Australia.

Background: The role of intravenous hydration at the time of primary percutaneous intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) remains unclear. Guidelines are vague, supported by low level evidence, and hydration is used less often than other clinical settings.To perform a systematic review and meta-analysis of all randomized controlled trials assessing intravenous hydration compared with non-hydration for prevention of contrast induced nephropathy (CIN) and In-hospital mortality in patients with STEMI undergoing primary PCI. Read More

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http://dx.doi.org/10.1186/s12872-019-1054-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454772PMC
April 2019
1 Read

Distinguishing Different Emotions Evoked by Music via Electroencephalographic Signals.

Comput Intell Neurosci 2019 6;2019:3191903. Epub 2019 Mar 6.

Luneng New Energy (Group) Co., Beijing, China.

Music can evoke a variety of emotions, which may be manifested by distinct signals on the electroencephalogram (EEG). Many previous studies have examined the associations between specific aspects of music, including the subjective emotions aroused, and EEG signal features. However, no study has comprehensively examined music-related EEG features and selected those with the strongest potential for discriminating emotions. Read More

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http://dx.doi.org/10.1155/2019/3191903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431402PMC
March 2019
1 Read

Product Module Network Modeling and Evolution Analysis.

Comput Intell Neurosci 2019 6;2019:2186916. Epub 2019 Mar 6.

College of Mechanical and Electrical Engineering, Shaanxi University of Science and Technology, Xi'an 710021, Shaanxi, China.

Modular technology for product design and manufacturing is an effective way to solve mass customization problems. One difficulty in the application of modular technology is that the characteristics of mass customization, such as multi batch and small batch, easily increase the complexity of the module structure of the enterprise products. To address this problem, based on complex network theory, the enterprise products module is mapped as the vertex of the network, the number of modules used is mapped as the node weight, the dependency between the modules is mapped to the edge, and the product module network is established. Read More

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http://dx.doi.org/10.1155/2019/2186916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431406PMC
March 2019
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The efficacy and safety of Tipapkinogen Sovacivec therapeutic HPV vaccine in cervical intraepithelial neoplasia grades 2 and 3: Randomized controlled phase II trial with 2.5 years of follow-up.

Gynecol Oncol 2019 Apr 2. Epub 2019 Apr 2.

Roche Pharmaceutical Research & Early Development, Roche Innovation Center New York, 430 E. 29th Street New York City, New York 10016, USA. Electronic address:

Background: While prophylactic human papillomavirus (HPV) vaccination exists, women are still developing cervical intraepithelial neoplasia (CIN) grade 2 or 3 for which an immunotherapeutic, non-surgical, approach may be effective. The primary aim was to assess the efficacy of tipapkinogen sovacivec (TS) vaccine in achieving histologic resolution of CIN2/3 associated with high risk (HR) HPV types.

Methods: Women 18 years and older who had confirmed CIN2/3 were enrolled in a randomized, double blind, placebo-controlled phase II trial and assigned to drug in a 2:1 ratio (vaccine:placebo). Read More

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http://dx.doi.org/10.1016/j.ygyno.2019.03.250DOI Listing
April 2019
1 Read

Complementarity between miRNA expression analysis and DNA methylation analysis in hrHPV-positive cervical scrapes for the detection of cervical disease.

Epigenetics 2019 Apr 8:1-10. Epub 2019 Apr 8.

a Pathology, Cancer Center Amsterdam , Amsterdam UMC, Vrije Universiteit Amsterdam , Amsterdam , The Netherlands.

Cervical screening by high-risk HPV (hrHPV) testing requires additional risk stratification (triage), as most infections are transient and only a subset of hrHPV-positive women harbours clinically relevant disease. Molecular triage markers such as microRNAs (miRNAs) and DNA methylation markers are particularly promising, as they can be objectively tested directly on hrHPV-positive scrapes and cervicovaginal self-samples. Here, we evaluated the marker potential of 10 candidate miRNAs in 209 hrHPV-positive scrapes of women with underlying precancer (cervical intraepithelial neoplasia, grade 2-3 (CIN2-3)), cancer, or without disease (CIN0/1). Read More

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http://dx.doi.org/10.1080/15592294.2019.1600390DOI Listing
April 2019
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Alternative splicing of the tumor suppressor ASPP2 results in a stress-inducible, oncogenic isoform prevalent in acute leukemia.

EBioMedicine 2019 Apr 2. Epub 2019 Apr 2.

Department of Oncology, Hematology, Rheumatology, Immunology and Pulmology, University Hospital Tübingen, Germany. Electronic address:

Background: Apoptosis-stimulating Protein of TP53-2 (ASPP2) is a tumor suppressor enhancing TP53-mediated apoptosis via binding to the TP53 core domain. TP53 mutations found in cancers disrupt ASPP2 binding, arguing for an important role of ASPP2 in TP53-mediated tumor suppression. We now identify an oncogenic splicing variant, ASPP2κ, with high prevalence in acute leukemia. Read More

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http://dx.doi.org/10.1016/j.ebiom.2019.03.028DOI Listing

Plagiarism in Predatory Publications: A Comparative Study of Three Nursing Journals.

J Nurs Scholarsh 2019 Apr 5. Epub 2019 Apr 5.

Delta Pi, Eta Iota, and Kappa Zeta-at-Large, Editor-in-Chief, CIN: Computers, Informatics, Nursing and Nurse Author & Editor, President and Owner, Maine Desk, LLC, Portland, ME, USA.

Purpose: This study compared three known predatory nursing journals to determine the percentage of content among them that was plagiarized or duplicated. A serendipitous finding of several instances of plagiarism via duplicate publications during the random analysis of articles in a study examining the quality of articles published in predatory journals prompted this investigation.

Design: The study utilized a descriptive, comparative design. Read More

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http://dx.doi.org/10.1111/jnu.12475DOI Listing

Deep Learning Network for Multiuser Detection in Satellite Mobile Communication System.

Comput Intell Neurosci 2019 4;2019:8613639. Epub 2019 Mar 4.

College of Engineering, Xi'an International University, Xi'an 710077, China.

A multiuser detection (MUD) algorithm based on deep learning network is proposed for the satellite mobile communication system. Due to relative motion between the satellite and users, multiple access interference (MUI) introduced by multipath fading channel reduces system performance. The proposed MUD algorithm based on deep learning network firstly establishes the CINR optimal loss function according to the multiuser access mode and then obtains the best multiuser detection weight through the steepest gradient iteration. Read More

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http://dx.doi.org/10.1155/2019/8613639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425414PMC

Gastric hepatoid adenocarcinomas are a genetically heterogenous group; most tumors show ‘chromosomal instability,’ but ‘MSI’ tumors do exist.

Hum Pathol 2019 Apr 1. Epub 2019 Apr 1.

Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. Electronic address:

The Cancer Genome Atlas Research Network classified gastric adenocarcinoma into four molecular subtypes: (1) Epstein-Barr virus-positive (EBV), (2) microsatellite-instable (MSI), (3) chromosomal instability (CIN), and (4) genomically stable (GS). The molecular subtypes of gastric hepatoid adenocarcinomas are still largely unknown. We analyzed 52 hepatoid adenocarcinomas for the expression of surrogate markers of molecular subtypes (MLH1, p53, and EBER in situ hybridization) and some biomarkers (p21, p16, Rb, cyclin D1, cyclin E, β-catenin, Bcl-2, IMP3, ARID1A and HER2), and mutations of TP53, CTNNB1, KRAS, and BRAF. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00468177193005
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http://dx.doi.org/10.1016/j.humpath.2019.03.006DOI Listing
April 2019
3 Reads

Patricia Flatley Brennan on Nursing Informatics and the National Library of Medicine.

Comput Inform Nurs 2019 Apr;37(4):187-189

The University of Alabama, Tuscaloosa, AL.

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http://dx.doi.org/10.1097/CIN.0000000000000533DOI Listing
April 2019
1 Read

"Would You Like to Skype With Your Daughter?": A Qualitative Feasibility Study of Video Telecommunication in a Psychogeriatric Hospital.

Comput Inform Nurs 2019 Apr;37(4):181-186

Author Affiliations: Geriatric Centre at the University Hospital Tuebingen Drs Niebler, Eschweiler, Dresler, and Metzger); Department of Psychology, Eberhard Karls University of Tuebingen, (Dr Niebler); Department for Psychiatry and Psychotherapy, University Hospital Tuebingen (Dr Eschweiler); LEAD Graduate School & Research Network, Eberhard Karls University of Tuebingen (Dr Dresler); Institute of Occupational and Social Medicine and Health Services Research, University Hospital Tuebingen (Dr Rieger); Coordination Centre, Core Facility for Health Services Research, Faculty of Medicine, Eberhard Karls University of Tuebingen (Dr Rieger); and Vitos Klinik für Psychiatrie und Psychotherapie Haina (Dr Metzger), Germany.

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http://dx.doi.org/10.1097/CIN.0000000000000534DOI Listing
April 2019
1 Read

Retinal dystrophies with bull's-eye maculopathy along with negative ERGs.

Doc Ophthalmol 2019 Apr 3. Epub 2019 Apr 3.

Centre for Ophthalmology, University of Tuebingen, Tübingen, Germany.

Purpose: The aim of this study was to examine the ophthalmological characteristics and genotypes of patients with congenital retinal pathologies, who display a bull's-eye maculopathy in the fundus, along with a negative scotopic electroretinogram.

Methods: We analysed the results of five patients showing both a bull's-eye maculopathy, as well as a negative scotopic ERG evoked by a bright flash. Their median age was 39 years (range 11-63 years): three males and two females. Read More

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http://dx.doi.org/10.1007/s10633-019-09694-7DOI Listing
April 2019
1 Read

IARNN-Based Semantic-Containing Double-Level Embedding Bi-LSTM for Question-and-Answer Matching.

Comput Intell Neurosci 2019 3;2019:6074840. Epub 2019 Mar 3.

College of Electronics and Information Engineering, Sichuan University, Chengdu 610065, China.

We propose a novel end-to-end approach, namely, the semantic-containing double-level embedding Bi-LSTM model (SCDE-Bi-LSTM), to solve the three key problems of Q&A matching in the Chinese medical field. In the similarity calculation of the Q&A core module, we propose a text similarity calculation method that contains semantic information, to solve the problem that previous Q&A methods do not incorporate the deep information of a sentence into the similarity calculations. For the sentence vector representation module, we present a double-level embedding sentence representation method to reduce the error caused by Chinese medical word segmentation. Read More

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http://dx.doi.org/10.1155/2019/6074840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421739PMC

Study on Hesitant Fuzzy Information Measures and Their Clustering Application.

Comput Intell Neurosci 2019 3;2019:5370763. Epub 2019 Mar 3.

School of Economics and Management, Huainan Normal University, Huainan 232038, China.

At present, research on hesitant fuzzy operations and measures is based on equal length processing, and an equal length processing method will inevitably destroy the original data structure and change the data information. This is an urgent problem to be solved in the development of hesitant fuzzy sets. Aiming at solving this problem, this paper firstly defines a hesitant fuzzy entropy function as the measure of the degree of uncertainty of hesitant fuzzy information and then proposes the concept of hesitant fuzzy information feature vector. Read More

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http://dx.doi.org/10.1155/2019/5370763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421787PMC

Using Morphological Data in Language Modeling for Serbian Large Vocabulary Speech Recognition.

Comput Intell Neurosci 2019 3;2019:5072918. Epub 2019 Mar 3.

Department for Power, Electronic and Telecommunication Engineering, Faculty of Technical Sciences, University of Novi Sad, 21000 Novi Sad, Serbia.

Serbian is in a group of highly inflective and morphologically rich languages that use a lot of different word suffixes to express different grammatical, syntactic, or semantic features. This kind of behaviour usually produces a lot of recognition errors, especially in large vocabulary systems-even when, due to good acoustical matching, the correct lemma is predicted by the automatic speech recognition system, often a wrong word ending occurs, which is nevertheless counted as an error. This effect is larger for contexts not present in the language model training corpus. Read More

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http://dx.doi.org/10.1155/2019/5072918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421827PMC

Optimized Complex Network Method (OCNM) for Improving Accuracy of Measuring Human Attention in Single-Electrode Neurofeedback System.

Comput Intell Neurosci 2019 3;2019:2167871. Epub 2019 Mar 3.

School of Innovations, Sanjiang University, Nanjing 210012, China.

A neurofeedback system adjusting an individual's attention is an effective treatment for attention-deficit/hyperactivity disorder (ADHD). In current studies, an accurate measure of the level of human attention is one of the key issues that arouse much interest. This paper proposes a novel optimized complex network method (OCNM) for measuring an individual's attention level using single-electrode electroencephalography (EEG) signals. Read More

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http://dx.doi.org/10.1155/2019/2167871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421751PMC
March 2019
3 Reads

Prevalence of cervical disease at age 20 after immunisation with bivalent HPV vaccine at age 12-13 in Scotland: retrospective population study.

BMJ 2019 Apr 3;365:l1161. Epub 2019 Apr 3.

Institute of Applied Health Services, University of Aberdeen, Aberdeen, UK.

Objective: To quantify the effect on cervical disease at age 20 years of immunisation with bivalent human papillomavirus (HPV) vaccine at age 12-13 years.

Design: Retrospective population study, 1988-96.

Setting: National vaccination and cervical screening programmes in Scotland. Read More

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http://dx.doi.org/10.1136/bmj.l1161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446188PMC
April 2019
2 Reads

Exosomal let-7d-3p and miR-30d-5p as diagnostic biomarkers for non-invasive screening of cervical cancer and its precursors.

Mol Cancer 2019 04 2;18(1):76. Epub 2019 Apr 2.

Center for Uterine Cancer Diagnosis & Therapy Research of Zhejiang Province, Women's Reproductive Health Key Laboratory of Zhejiang Province, Department of Gynecologic Oncology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Cervical cancer screening through detection and treatment of high-grade cervical intraepithelial neoplasia (CIN) is most successful in cancer prevention. However, the accuracy of the current cervical cancer screening tests is still low. The aim of this study was to develop a more accurate method based on circulating exosomal miRNAs. Read More

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http://dx.doi.org/10.1186/s12943-019-0999-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446401PMC
April 2019
3 Reads
4.257 Impact Factor

The AASPIRE practice-based guidelines for the inclusion of autistic adults in research as co-researchers and study participants.

Autism 2019 Apr 3:1362361319830523. Epub 2019 Apr 3.

3 Community Council, Academic Autism Spectrum Partnership in Research and Education, Portland, OR, USA.

As interest in autism in adulthood grows, so does the need for methods to promote the inclusion of autistic adults in research. Our objective was to create practice-based guidelines for the inclusion of autistic adults, both as research team members and as study participants. We conducted an institutional ethnography of three closely related research partnerships that used participatory methods with autistic adults over the years 2006-2018. Read More

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http://dx.doi.org/10.1177/1362361319830523DOI Listing
April 2019
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Motion Simulation of Ionic Liquid Gel Soft Actuators Based on CPG Control.

Comput Intell Neurosci 2019 26;2019:8256723. Epub 2019 Feb 26.

College of Electronics and Information Engineering, Tongji University, No. 4800 Caoan Road, Shanghai 201804, China.

The ionic liquid gel (ILG), a new type of soft actuator material, is a mixture of 1-butyl-3-methylimidazolium tetrafluoroborate (BMIMBF), hydroxyethyl methacrylate (HEMA), diethoxyacetophenone (DEAP), and ZrO polymerized into a gel state under ultraviolet (UV) light irradiation. The soft actuator structure consists of a layer of ionic liquid polymer gel sandwiched between two layers of activated carbon capped with gold foil. The volume of the cationic BMIM in the ionic liquid BMIMBF is much larger than that of the anionic BF. Read More

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https://www.hindawi.com/journals/cin/2019/8256723/
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http://dx.doi.org/10.1155/2019/8256723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413395PMC
February 2019
3 Reads

Position Estimation Based on Grid Cells and Self-Growing Self-Organizing Map.

Comput Intell Neurosci 2019 26;2019:3606397. Epub 2019 Feb 26.

College of Information and Navigation, Air Force Engineering University, Xi'an, China.

As the basis of animals' natal homing behavior, path integration can continuously provide current position information relative to the initial position. Some neurons in freely moving animals' brains can encode current positions and surrounding environments by special firing patterns. Research studies show that neurons such as grid cells (GCs) in the hippocampus of animals' brains are related to the path integration. Read More

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http://dx.doi.org/10.1155/2019/3606397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413409PMC
February 2019
1 Read

Arabic Sentiment Classification Using Convolutional Neural Network and Differential Evolution Algorithm.

Comput Intell Neurosci 2019 26;2019:2537689. Epub 2019 Feb 26.

School of Computer Science and Technology, Wuhan University of Technology, 122 Luoshi Road, Wuhan, Hubei 430070, China.

In recent years, convolutional neural network (CNN) has attracted considerable attention since its impressive performance in various applications, such as Arabic sentence classification. However, building a powerful CNN for Arabic sentiment classification can be highly complicated and time consuming. In this paper, we address this problem by combining differential evolution (DE) algorithm and CNN, where DE algorithm is used to automatically search the optimal configuration including CNN architecture and network parameters. Read More

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http://dx.doi.org/10.1155/2019/2537689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413408PMC
February 2019

Features of formation of biofilms.

Vet World 2019 Jan 25;12(1):136-140. Epub 2019 Jan 25.

Department of Agrobiotechnology, Agrarian Technological Institute, Peoples' Friendship University of Russia, Moscow, Russia.

Aim: The work aimed to study the morphology of colonies and their comparison by features of the formation of biofilms.

Materials And Methods: Bacteria were cultured on a Yersinia Selective Agar medium ("CIN-agar") at 28°C for 24 h. The microorganisms were grown in meat-peptone broth with 1. Read More

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http://www.veterinaryworld.org/Vol.12/January-2019/20.html
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http://dx.doi.org/10.14202/vetworld.2019.136-140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431818PMC
January 2019
4 Reads

Genetic Factors Associated with a Poor Outcome in Head and Neck Cancer Patients Receiving Definitive Chemoradiotherapy.

Cancers (Basel) 2019 Mar 29;11(4). Epub 2019 Mar 29.

Division of Cell Biology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

About half of advanced stage head and neck squamous cell carcinoma (HNSCC) patients can be cured by chemoradiotherapy. Patient outcome may be partially determined by the genetic alterations in HNSCC, rendering these alterations promising candidate prognostic factors and/or therapeutic targets. However, their relevance in patient outcome prognosis remains to be assessed in patients that receive standard-of-care chemoradiotherapy. Read More

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https://www.mdpi.com/2072-6694/11/4/445
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http://dx.doi.org/10.3390/cancers11040445DOI Listing
March 2019
6 Reads

Clinical outcome of high-grade cervical intraepithelial neoplasia during pregnancy: A 10-year experience.

Eur J Obstet Gynecol Reprod Biol 2019 Mar 25;236:173-176. Epub 2019 Mar 25.

Department of Obstetrics and Gynecology, Konkuk University School of Medicine, Seoul, Republic of Korea. Electronic address:

Objective: To investigate the clinical outcome of high-grade cervical intraepithelial neoplasia (CIN) diagnosed by colposcopy-directed biopsy during pregnancy and to evaluate the risk factors for persistent disease.

Study Design: This retrospective study included pregnant women who were diagnosed with CIN2+ by colposcopy-directed biopsy from January 2005 to December 2014. The clinical characteristics, histopathologic results, and human papillomavirus (HPV) test results were reviewed. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2019.03.023DOI Listing
March 2019
2 Reads
1.627 Impact Factor

The effects of sustained virological response to direct-acting anti-viral therapy on the risk of extrahepatic manifestations of hepatitis C infection.

Aliment Pharmacol Ther 2019 Apr 1. Epub 2019 Apr 1.

Houston VA HSR&D Center for Innovations in Quality, Effectiveness and Safety, Michael E DeBakey VA Medical Center, Houston, Texas.

Background: Direct-acting anti-viral (DAA) therapy may have a beneficial role in extrahepatic manifestations of hepatitis C virus (HCV) infection. However, the available data are limited.

Aim: To examine the effects of DAA treatment on the risk of several extrahepatic manifestations of HCV. Read More

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http://dx.doi.org/10.1111/apt.15240DOI Listing
April 2019
3 Reads

Study of Hybrid Neurofuzzy Inference System for Forecasting Flood Event Vulnerability in Indonesia.

Comput Intell Neurosci 2019 25;2019:6203510. Epub 2019 Feb 25.

Postgraduate of Information System Department, Universitas Komputer Indonesia, No. 102-116 Dipati Ukur, Bandung, West Java 40132, Indonesia.

An experimental investigation was conducted to explore the fundamental difference among the Mamdani fuzzy inference system (FIS), Takagi-Sugeno FIS, and the proposed flood forecasting model, known as hybrid neurofuzzy inference system (HN-FIS). The study aims finding which approach gives the best performance for forecasting flood vulnerability. Due to the importance of forecasting flood event vulnerability, the Mamdani FIS, Sugeno FIS, and proposed models are compared using trapezoidal-type membership functions (MFs). Read More

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http://dx.doi.org/10.1155/2019/6203510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410442PMC
February 2019

Positive effects of acupressure bands combined with relaxation music/instructions on patients most at risk for chemotherapy-induced nausea.

Support Care Cancer 2019 Mar 30. Epub 2019 Mar 30.

Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA.

Purpose: Research by our group has shown that acupressure bands are efficacious in reducing chemotherapy-induced nausea (CIN) for breast cancer patients who expect nausea, and that their effectiveness in controlling CIN can largely be accounted for by patients' expectations of efficacy, i.e., a placebo effect. Read More

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http://dx.doi.org/10.1007/s00520-019-04736-xDOI Listing
March 2019
1 Read