12,986 results match your criteria CIN: Computers Informatics Nursing[Journal]


Erratum: Ciliary muscle thickness profiles derived from optical coherence tomography images: erratum.

Biomed Opt Express 2019 Jan 7;10(1):119. Epub 2018 Dec 7.

Institute for Ophthalmic Research, Eberhard Karls University Tuebingen, Elfriede-Aulhorn-Str. 7, 72076 Tuebingen, Germany.

[This corrects the article on p. 5100 in vol. 9, PMID: 30319924. Read More

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https://www.osapublishing.org/abstract.cfm?URI=boe-10-1-119
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http://dx.doi.org/10.1364/BOE.10.000119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363208PMC
January 2019
1 Read

[The catalytic subunit of the anaphase-promoting complex, APC11, is involved in CIN CRC progression].

Med Sci (Paris) 2019 Feb 18;35(2):118-122. Epub 2019 Feb 18.

Inserm U1052, CNRS UMR 5286, Cancer research center of Lyon, Lyon, F-69008, France - Centre Léon Bérard, 28, rue Laënnec, Lyon, F-69008, France - Université Lyon1, ISPB, Lyon, F-69008, France - Université de Lyon, Lyon, F-69622, France - LabEx DEVweCAN, Université de Lyon, F-69000 Lyon, France.

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http://dx.doi.org/10.1051/medsci/2019020DOI Listing
February 2019

Development of evidence-based quality indicators for deep brain stimulation in patients with Parkinson's disease and first year experience of implementation of a nation-wide registry.

Parkinsonism Relat Disord 2019 Feb 5. Epub 2019 Feb 5.

Institute for Clinical Epidemiology and Biometry, University of Würzburg, Würzburg, Germany; Comprehensive Heart Failure Center, University Würzburg, Clincial Trial Center Würzburg, University Hospital Würzburg, Germany.

Introduction: Deep Brain Stimulation (DBS) is a complex, invasive and cost-intensive therapy that requires a high level of expertise. To date, data on quality of DBS in clinical routine in the German health care system are lacking.

Methods: The development of evidence-based QIs for DBS in PD patients was performed following a standardized process by a multidisciplinary board between 2014 and 2016. Read More

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http://dx.doi.org/10.1016/j.parkreldis.2019.01.016DOI Listing
February 2019

Exploring the utility of the Chasing Principle: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension.

Acta Pharm Sin B 2019 Jan 7;9(1):194-201. Epub 2018 Jul 7.

Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2100, Denmark.

This study assessed the influence of the composition of drug-free SNEDDS co-dosed with aqueous suspensions of carvedilol (CAR), cinnarizine (CIN) or R3040 on drug solubilization in a two-compartment lipolysis model. Correlation of drug log or solubility in SNEDDS with drug solubilization during lipolysis in the presence of drug-free SNEDDS was assessed. SNEDDS with varying ratios of soybean oil:Maisine 35-1 (1:1, /) and Kolliphor RH40, with ethanol at 10% (/) were used. Read More

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http://dx.doi.org/10.1016/j.apsb.2018.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361727PMC
January 2019

Timeout for Contrast: Using Physician Behavior Modification to Reduce Contrast in the Catheterization Laboratory.

Cardiol Res Pract 2019 15;2019:9238124. Epub 2019 Jan 15.

Providence Hospital/Michigan State University, Southfield, MI, USA.

Background: As the number of procedures using contrast media continues to rise, the ensuing complications place an ever increasing burden on the healthcare system. Contrast-induced nephropathy (CIN) is a common postprocedural complication after cardiac catheterization.

Objectives: The purpose of our study was to evaluate the impact of physician behavioral modification on reducing the amount of contrast used during the procedure. Read More

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http://dx.doi.org/10.1155/2019/9238124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350551PMC
January 2019

Thyroid Diagnosis from SPECT Images Using Convolutional Neural Network with Optimization.

Comput Intell Neurosci 2019 15;2019:6212759. Epub 2019 Jan 15.

Nuclear Medicine Department, Heilongjiang Provincial Hospital, Harbin 150030, China.

Thyroid disease has now become the second largest disease in the endocrine field; SPECT imaging is particularly important for the clinical diagnosis of thyroid diseases. However, there is little research on the application of SPECT images in the computer-aided diagnosis of thyroid diseases based on machine learning methods. A convolutional neural network with optimization-based computer-aided diagnosis of thyroid diseases using SPECT images is developed. Read More

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http://dx.doi.org/10.1155/2019/6212759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350547PMC
January 2019

Detecting Happiness Using Hyperspectral Imaging Technology.

Comput Intell Neurosci 2019 15;2019:1965789. Epub 2019 Jan 15.

College of Computer and Information Science, Southwest University, Chongqing, China.

Hyperspectral imaging (HSI) technology can be used to detect human emotions based on the power of material discrimination from their faces. In this paper, HSI is used to remotely sense and distinguish blood chromophores in facial tissues and acquire an evaluation indicator (tissue oxygen saturation, StO) using an optical absorption model. This study explored facial analysis while people were showing spontaneous expressions of happiness during social interaction. Read More

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http://dx.doi.org/10.1155/2019/1965789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350538PMC
January 2019

Nursing Value User Stories: A Value Measurement Method for Linking Nurse Contribution to Patient Outcomes.

Comput Inform Nurs 2019 Feb 12. Epub 2019 Feb 12.

Author Affiliations: School of Nursing, University of Minnesota, Minneapolis (Drs Moon and Clancy); and Advocate Consulting (Dr Moon), Apple Valley, MN; School of Nursing, University of Colorado-Denver (Dr Welton); and University of Kansas, School of Nursing (Dr Harper), Kansas City.

The use of nursing big data sets for value-based measurement is novel. Nursing value measurement depends on the availability of essential data attributes in the electronic health record related to nursing care delivered (what happened, when, and the result seen). Key in measuring value is a standardized structure and format of these attributes for enabling uniform consistent analysis, along with data sets that are sharable and comparable across individuals and groups, time, organization, and practice focus. Read More

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http://dx.doi.org/10.1097/CIN.0000000000000520DOI Listing
February 2019

Distinct contributions of human posterior parietal and dorsal premotor cortex to reach trajectory planning.

Sci Rep 2019 Feb 13;9(1):1962. Epub 2019 Feb 13.

Hertie-Institute for Clinical Brain Research, Department of Cognitive Neurology, Hoppe-Seyler-Str. 3, 72076, Tuebingen, Germany.

Goal-directed hand movements are usually directed straight at the target, e.g. when swatting a fly. Read More

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http://dx.doi.org/10.1038/s41598-019-39188-0DOI Listing
February 2019

Clinical, Electroencephalographic Features and Prognostic Factors of Cefepime-Induced Neurotoxicity: A Retrospective Study.

Neurocrit Care 2019 Feb 12. Epub 2019 Feb 12.

Section of Epilepsy, Department of Neurology, Chang Gung Memorial Hospital at Linkou Medical Center and Chang Gung University College of Medicine, 5 Fuxing St., Guishan Dist., Taoyuan, 333, Taiwan.

Background: The incidence of cefepime-induced neurotoxicity (CIN) has been previously underestimated, and there have only been sporadic reports from critical neurological settings. The present study aimed to investigate the potential factors associated with disease development, electroencephalography (EEG) sub-classification, and outcome measures.

Methods: The 10-year medical records of patients who underwent EEG between 2007 and 2016 at a tertiary medical center in Taiwan, and developed encephalopathy after cefepime therapy were retrospectively reviewed. Read More

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http://dx.doi.org/10.1007/s12028-019-00682-yDOI Listing
February 2019

Molecular Diagnosis of Human Papilloma Virus by PCR.

Mymensingh Med J 2019 Jan;28(1):175-181

Dr Faijun Nahar, Assistant Professor, Department of Microbiology, President Abdul Hamid Medical College, Kishoreganj, Bangladesh.

Cervical cancer is a major world health problem and the fourth most leading cause of death in women around the world. High risk HPV DNA has been shown to be present in 99.7% of cervical cancers worldwide. Read More

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January 2019

Consequences of Genomic Diversification Induced by Segregation Errors.

Trends Genet 2019 Feb 8. Epub 2019 Feb 8.

Oncode Institute, Division of Cell Biology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands. Electronic address:

Chromosome segregation errors are an important source of genomic diversification that promote tumor heterogeneity and evolution. However, the aneuploidy induced by chromosome missegregations causes cellular stress at many levels, raising the question of how segregation errors can be tolerated in cancer. Additionally, we now know that chromosome segregation errors can lead to activation of the innate immune system, producing yet another challenge for chromosomally unstable cells. Read More

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http://dx.doi.org/10.1016/j.tig.2019.01.003DOI Listing
February 2019

The predictive value of the renal resistive index for contrast-induced nephropathy in patients with acute coronary syndrome.

BMC Cardiovasc Disord 2019 Feb 11;19(1):36. Epub 2019 Feb 11.

Southern Medical University , Guangzhou, 510515, China.

Background: Percutaneous coronary intervention (PCI) has been associated with contrast-induced nephropathy (CIN) at a rate that varies depending on the patient's risk factors. This study was conducted to evaluate the predictive value of the renal resistive index (RRI) for CIN in patients with acute coronary syndrome (ACS) undergoing PCI.

Methods: This prospective study enrolled 146 consecutive patients with ACS. Read More

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http://dx.doi.org/10.1186/s12872-019-1017-3DOI Listing
February 2019
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The CIN-TCP transcription factors promote commitment to differentiation in Arabidopsis leaf pavement cells via both auxin-dependent and independent pathways.

PLoS Genet 2019 Feb 11;15(2):e1007988. Epub 2019 Feb 11.

Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.

Cells in organ primordia undergo active proliferation at an early stage to generate sufficient number, before exiting proliferation and entering differentiation. However, how the actively proliferating cells are developmentally reprogrammed to acquire differentiation potential during organ maturation is unclear. Here, we induced a microRNA-resistant form of TCP4 at various developmental stages of Arabidopsis leaf primordium that lacked the activity of TCP4 and its homologues and followed its effect on growth kinematics. Read More

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http://dx.doi.org/10.1371/journal.pgen.1007988DOI Listing
February 2019

Factors Related to Health Informatics Competencies for Nurses-Results of a National Electronic Health Record Survey.

Comput Inform Nurs 2019 Feb 7. Epub 2019 Feb 7.

Author Affiliations: University of Eastern Finland, Kuopio (Dr Kinnunen); National Institute for Health and Welfare, Helsinki (Drs Heponiemi and Hyppönen); Laurea University of Applied Sciences, Vantaa (Dr Rajalahti and Ms Outi); The Finnish Nurses Association, Helsinki (Dr Korhonen), Finland.

In 2015, the Finnish Ministry of Social Affairs and Health published an eHealth and eSocial strategy with key objectives that by 2020 health information systems will be smart and providers will be able to maximize their use. Measures include improving system usability and decision support, involving professionals in system and service development, and increasing professionals' training in information management, electronic documentation, data protection, and data security. The aim of this study was to explore the level of nurses' informatics competencies and sufficiency of in-house training regarding technology-induced changes in work practices. Read More

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http://dx.doi.org/10.1097/CIN.0000000000000511DOI Listing
February 2019

Post-hoc analysis from phase iii trials of human papillomavirus vaccines: considerations on impact on non-vaccine types.

Expert Rev Vaccines 2019 Feb 11. Epub 2019 Feb 11.

c GSK , Rixensart , Belgium.

Background: Substantial heterogeneity has been reported in efficacy against high-grade cervical intraepithelial neoplasia (CIN) irrespective of type in phase III results for bivalent and quadrivalent human papillomavirus virus (HPV) vaccines (AS04-HPV and qHPV). Real-world data recently confirmed very high overall impact of AS04-HPV, supporting the validity of the observed heterogeneity. To explore the reasons for heterogeneous efficacy, we assessed vaccine impact on high-grade lesions not caused by vaccine types. Read More

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http://dx.doi.org/10.1080/14760584.2019.1579647DOI Listing
February 2019
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A Retrospective Analysis of the Effects of Chemotherapy-Induced Neutropenia on Overall Survival in Patients With Unresectable or Metastatic Urothelial Carcinoma to Gemcitabine Plus Cisplatin Combination Chemotherapy.

Ann Pharmacother 2019 Feb 8:1060028019830785. Epub 2019 Feb 8.

1 SEIREI Hamamatsu General Hospital, Naka-ku, Japan.

Background: Chemotherapy-induced neutropenia (CIN) is an important dose-limiting toxicity of chemotherapy. However, evidence suggests that the occurrence of CIN may be predictive of treatment outcome. Indeed, studies have revealed that the onset of CIN is associated with a good chemotherapeutic response. Read More

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http://dx.doi.org/10.1177/1060028019830785DOI Listing
February 2019
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HPV-Chlamydial Coinfection, Prevalence, and Association with Cervical Intraepithelial Lesions: A Pilot Study at Mbarara Regional Referral Hospital.

J Cancer Epidemiol 2019 10;2019:9092565. Epub 2019 Jan 10.

PhD, (MUK), Makerere University, College of Health Science, P.O. Box 7072, Kampala, Uganda.

Background: Human Pappilloma Virus (HPV) is the necessary cause of cervical cancer. A number of risk factors are believed to influence the role of HPV in the development of cervical cancer. This is so because majority of HPV infections are cleared and only a few are able to result into cancer. Read More

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http://dx.doi.org/10.1155/2019/9092565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348791PMC
January 2019
1 Read

Application of EEG and Interactive Evolutionary Design Method in Cultural and Creative Product Design.

Authors:
Li Deng Guohua Wang

Comput Intell Neurosci 2019 13;2019:1860921. Epub 2019 Jan 13.

State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation, Southwest Petroleum University, Chengdu 610500, China.

In order to design a cultural and creative product that matched the target image, this paper proposed to use EEG, interactive genetic algorithm (IGA), and back propagation neural network (BPNN) to analyze the users' image preferences. Firstly, the pictures of cultural elements were grouped according to the pleasantness value and emotional state by PAD emotion scale, and the brain waves induced by the pictures of cultural elements with different pleasure degree were recorded by electroencephalograph. Then, the preference of cultural elements was obtained according to the theory of frontal alpha asymmetry. Read More

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http://dx.doi.org/10.1155/2019/1860921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348831PMC
January 2019

Virtual Postoperative Visits for New Ostomates.

Authors:

Comput Inform Nurs 2019 Feb;37(2):116-117

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http://dx.doi.org/10.1097/01.NCN.0000553172.40576.0cDOI Listing
February 2019

Documentation Burden and Cognitive Burden: How Much is Too Much Information?

Authors:
Joni Padden

Comput Inform Nurs 2019 Feb;37(2):60-61

Texas Health Resources, Arlington.

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http://dx.doi.org/10.1097/CIN.0000000000000522DOI Listing
February 2019

The First Step Toward Reducing Documentation: Defining Ideal Workflows.

Comput Inform Nurs 2019 Feb;37(2):57-59

Author Affiliation: HCA | Clinical Services Group, Nashville, Tennessee.

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http://dx.doi.org/10.1097/CIN.0000000000000519DOI Listing
February 2019

Fuzzy Evaluation of Pharmacokinetic Models.

Comput Intell Neurosci 2018 1;2018:1983897. Epub 2018 Nov 1.

Instituto Politécnico Nacional, Centro de Investigación y Desarrollo de Tecnología Digital (CITEDI-IPN), Av. Instituto Politécnico Nacional, No. 1310, Col. Nueva Tijuana, 22435 Tijuana, BC, Mexico.

Population pharmacokinetic (PopPK) models allow researchers to predict and analyze drug behavior in a population of individuals and to quantify the different sources of variability among these individuals. In the development of PopPK models, the most frequently used method is the nonlinear mixed effect model (NLME). However, once the PopPK model has been developed, it is necessary to determine if the selected model is the best one of the developed models during the population pharmacokinetic study, and this sometimes becomes a multiple criteria decision making (MCDM) problem, and frequently, researchers use statistical evaluation criteria to choose the final PopPK model. Read More

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http://dx.doi.org/10.1155/2018/1983897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341258PMC
November 2018

Cervical microbiota in women with cervical intra-epithelial neoplasia, prior to and after local excisional treatment, a Norwegian cohort study.

BMC Womens Health 2019 Feb 6;19(1):30. Epub 2019 Feb 6.

Department of Gynecology and Obstetrics, Østfold Hospital Trust, Kalnes, Norway.

Background: Local treatment for cervical intraepithelial neoplasia (CIN) by Loop Electrosurgical Excision Procedure (LEEP) has been correlated with reproductive morbidity, while the cervicovaginal microbiota is also known to affect the risk of preterm delivery. CIN and treatment by LEEP might change the cervical microbiota. The main aim of this study was to describe the cervical microbiota before and after LEEP and assess its associaton with cone depth and HPV persistence. Read More

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http://dx.doi.org/10.1186/s12905-019-0727-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364458PMC
February 2019
1 Read

Covert Intention to Answer to Self-Referential Questions Is Represented in Alpha-Band Local and Interregional Neural Synchronies.

Comput Intell Neurosci 2019 6;2019:7084186. Epub 2019 Jan 6.

Department of Biomedical Engineering, Yonsei University, Wonju 26493, Republic of Korea.

The most fundamental and simplest intention for interpersonal communication may be the intentions to answer "yes" or "no" to a question, based on a binary decision. However, the neural mechanism of this type of intention has not been investigated in detail. The main purpose of this study was to investigate cortical processing of the "yes/no" intentions to answer self-referential questions. Read More

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https://www.hindawi.com/journals/cin/2019/7084186/
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http://dx.doi.org/10.1155/2019/7084186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339759PMC
January 2019
1 Read

Nurse Decision Making in Acute Care.

Comput Inform Nurs 2019 Jan 31. Epub 2019 Jan 31.

Author Affiliations: Department of Biomedical Informatics, University of California, San Diego (Dr Nibbelink); and College of Nursing, University of Arizona, Tucson (Dr Carrington).

Effective nurse decision making is essential for best patient outcomes in the acute care nurse practice environment. The purpose of this study was to explore acute care RNs' perceptions of clinical decision making for a patient who experienced a clinical event. Clinical events include changes in patient condition and are manifested by fever, pain, bleeding, changes in output, changes in respiratory status, and changes in level of consciousness. Read More

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http://dx.doi.org/10.1097/CIN.0000000000000521DOI Listing
January 2019
2 Reads

Comparison of PapilloCheck and Linear Array to Detect and Differentiate Human Papillomaviruses in Cervical and Tonsillar Smears from Females with Cervical Intraepithelial Lesions.

Eur J Microbiol Immunol (Bp) 2018 Dec 12;8(4):107-111. Epub 2018 Dec 12.

Department of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Germany.

A subgroup of oropharyngeal squamous cell carcinomas (OSCCs) are causally linked to infection with high-risk human papillomaviruses (HR-HPVs). To evaluate the prevalence of simultaneous oral HPV infection in females with cervical high-grade squamous intraepithelial lesions (HSIL), tonsillar- and cervical smears were collected simultaneously from 73 patients and analyzed for HPV using two commercial assays, PapilloCheck (Greiner-Bio-One) and Linear Array (Roche). Only 3/73 (4. Read More

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https://www.akademiai.com/doi/10.1556/1886.2018.00018
Publisher Site
http://dx.doi.org/10.1556/1886.2018.00018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348707PMC
December 2018
3 Reads

Incoming Work-In-Progress Prediction in Semiconductor Fabrication Foundry Using Long Short-Term Memory.

Comput Intell Neurosci 2019 2;2019:8729367. Epub 2019 Jan 2.

X-FAB Sarawak Sdn. Bhd., 1 Silicon Drive, Sama Jaya Free Industrial Zone, 93350 Kuching, Sarawak, Malaysia.

Preventive maintenance activities require a tool to be offline for long hour in order to perform the prescribed maintenance activities. Although preventive maintenance is crucial to ensure operational reliability and efficiency of the tool, long hour of preventive maintenance activities increases the cycle time of the semiconductor fabrication foundry (Fab). Therefore, this activity is usually performed when the incoming Work-in-Progress to the equipment is forecasted to be low. Read More

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http://dx.doi.org/10.1155/2019/8729367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334351PMC
January 2019

Mechanical Energy Expenditure-based Comfort Evaluation Model for Gesture Interaction.

Comput Intell Neurosci 2018 30;2018:9861697. Epub 2018 Dec 30.

School of Mechanical Engineering, Northwestern Polytechnical University, Xi'an 710072, China.

As an advanced interaction mode, the gesture has been widely used for the human-computer interaction (HCI). The paper proposes a comfort evaluation model based on the mechanical energy expenditure (MEE) and the mechanical efficiency (ME) to predict the comfort of gestures. The proposed comfort evaluation model takes nineteen muscles and seven degrees of freedom into consideration based on the data of muscles and joints and is capable of simulating the MEE and the ME of both static and dynamic gestures. Read More

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http://dx.doi.org/10.1155/2018/9861697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335735PMC
December 2018
1 Read

Silencing the GUCA2A-GUCY2C tumor suppressor axis in CIN, serrated and MSI colorectal neoplasia.

Hum Pathol 2019 Feb 1. Epub 2019 Feb 1.

Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, 1020 Locust Street, Philadelphia, PA, United States. Electronic address:

Colorectal cancers (CRCs) initiate through distinct mutations, including in APC pathway components leading to tubular adenomas (TAs); in BRAF, with epigenetic silencing of CDX2, leading to serrated adenomas (SAs); and in the DNA mismatch repair machinery driving microsatellite instability (MSI). Transformation through the APC pathway involves loss of the hormone GUCA2A that silences the tumor suppressing receptor GUCY2C. Indeed, oral hormone replacement is an emerging strategy to reactivate GUCY2C and prevent CRC initiation and progression. Read More

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http://dx.doi.org/10.1016/j.humpath.2018.11.032DOI Listing
February 2019
1 Read

Association of Serum Osmolarity With Contrast-Induced Nephropathy in Patients With ST-Segment Elevation Myocardial Infarction.

Angiology 2019 Feb 3:3319719826466. Epub 2019 Feb 3.

1 Department of Cardiology, Osmaniye State Hospital, Osmaniye, Turkey.

Contrast-induced nephropathy (CIN) is a prevalent and serious complication after primary percutaneous coronary intervention (pPCI). Although the association between serum osmolarity and chronic kidney disease is well established, its relation to CIN in patients with ST-segment elevation myocardial infarction (STEMI) undergoing pPCI needs to be elucidated. We evaluated the predictive value of serum osmolarity for CIN development in patients with STEMI (n = 768) undergoing pPCI. Read More

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http://dx.doi.org/10.1177/0003319719826466DOI Listing
February 2019

Hypotrichosis with cone-rod dystrophy in a patient with cadherin 3 (CDH3) mutation.

Doc Ophthalmol 2019 Feb 1. Epub 2019 Feb 1.

Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tuebingen, Elfriede-Aulhorn Strasse 7, 72076, Tübingen, Germany.

Purpose: To investigate a very rare case of hypotrichosis with cone-rod dystrophy caused by a P-cadherin CDH3 mutation.

Methods: A 16-year-old Syrian girl was examined at age 9 and 14 years with an ophthalmological examination, fundus imaging, OCT and electrophysiological recordings (ERG and PERG). A disease-targeted gene panel sequencing was performed. Read More

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http://link.springer.com/10.1007/s10633-019-09675-w
Publisher Site
http://dx.doi.org/10.1007/s10633-019-09675-wDOI Listing
February 2019
2 Reads

Eye-position error influence over "open-loop" smooth pursuit initiation.

J Neurosci 2019 Feb 1. Epub 2019 Feb 1.

Werner Reichardt Centre for Integrative Neuroscience, Tuebingen University, Tuebingen, Germany, 72076.

The oculomotor system integrates a variety of visual signals into appropriate motor plans, but such integration can have widely varying time scales. For example, smooth pursuit eye movements to follow a moving target are slower and longer-lasting than saccadic eye movements, and it has been suggested that initiating a smooth pursuit eye movement involves an obligatory open-loop interval, in which new visual motion signals presumably cannot influence the ensuing motor plan for up to 100 ms after movement initiation. However, this view runs directly contrary to the idea that the oculomotor periphery has privileged access to short-latency visual signals. Read More

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http://dx.doi.org/10.1523/JNEUROSCI.2178-18.2019DOI Listing
February 2019

Sex differences in osteoporosis self-efficacy among community-residing older adults presenting for DXA.

Osteoporos Int 2019 Jan 30. Epub 2019 Jan 30.

Division of General Internal Medicine, Department of Internal Medicine, College of Medicine, University of Iowa Carver, Iowa City, IA, USA.

The Osteoporosis Self Efficacy Scale was determined to equivalently measure calcium and exercise beliefs in both sexes. Despite data illustrating men's and women's similar self-efficacy, gender differences in clinical predictors of self-efficacy imply that efforts to improve care must account for more than self-efficacy.

Introduction: To understand the extent to which the Osteoporosis Self Efficacy (OSE) Scale is reliable for both men and women. Read More

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http://dx.doi.org/10.1007/s00198-019-04854-6DOI Listing
January 2019
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Mafb and c-Maf Have Prenatal Compensatory and Postnatal Antagonistic Roles in Cortical Interneuron Fate and Function.

Cell Rep 2019 Jan;26(5):1157-1173.e5

Nina Ireland Laboratory of Developmental Neurobiology, Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA; Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

Mafb and c-Maf transcription factor (TF) expression is enriched in medial ganglionic eminence (MGE) lineages, beginning in late-secondary progenitors and continuing into mature parvalbumin (PV) and somatostatin (SST) interneurons. However, the functions of Maf TFs in MGE development remain to be elucidated. Herein, Mafb and c-Maf were conditionally deleted, alone and together, in the MGE and its lineages. Read More

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http://dx.doi.org/10.1016/j.celrep.2019.01.031DOI Listing
January 2019

Dysregulation of the cohesin subunit RAD21 by Hepatitis C virus mediates host-virus interactions.

Nucleic Acids Res 2019 Jan 30. Epub 2019 Jan 30.

Molecular Virology Lab, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.

Hepatitis C virus (HCV) infection is the leading cause of chronic hepatitis, which often results in liver fibrosis, cirrhosis and hepatocellular carcinoma (HCC). HCV possesses an RNA genome and its replication is confined to the cytoplasm. Yet, infection with HCV leads to global changes in gene expression, and chromosomal instability (CIN) in the host cell. Read More

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http://dx.doi.org/10.1093/nar/gkz052DOI Listing
January 2019
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Estimating the epidemiological impact and cost-effectiveness profile of a nonavalent hpv vaccine in Spain.

Hum Vaccin Immunother 2019 Jan 30. Epub 2019 Jan 30.

b Medical Department , MSD Spain , Madrid , Spain.

Human papillomavirus (HPV) is one of the main causes of infection-related cancer. The bivalent vaccine (2vHPV) (16/18) and quadrivalent (6/11/16/18) HPV vaccine (4vHPV) have been included in the Spanish vaccination calendar since 2007. The new nonavalent HPV vaccine (9vHPV), approved in Europe in 2015, includes nine HPV types 6/11/16/18/31/33/45/52/58 and has been available in Spain since May 2017. Read More

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http://dx.doi.org/10.1080/21645515.2018.1560770DOI Listing
January 2019

Genomic clustering of fitness-affecting mutations favors the evolution of chromosomal instability.

Evol Appl 2019 Feb 11;12(2):301-313. Epub 2018 Oct 11.

Department of Ecology and Evolutionary Biology, Center for Computational Molecular Biology Brown University Providence Rhode Island.

Most solid cancers are characterized by chromosomal instability (CIN)-an elevated rate of large-scale chromosomal aberrations and ploidy changes. Chromosomal instability may arise through mutations in a range of genomic integrity loci and is commonly associated with fast disease progression, poor prognosis, and multidrug resistance. However, the evolutionary forces promoting CIN-inducing alleles (hereafter, CIN mutators) during carcinogenesis remain poorly understood. Read More

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http://dx.doi.org/10.1111/eva.12717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346662PMC
February 2019

Genome-Wide Profiling of Cervical RNA-Binding Proteins Identifies Human Papillomavirus Regulation of RNASEH2A Expression by Viral E7 and E2F1.

MBio 2019 Jan 29;10(1). Epub 2019 Jan 29.

Tumor Virus RNA Biology Section, RNA Biology Laboratory, Center for Cancer Research, NCI/NIH, Frederick, Maryland, USA

RNA-binding proteins (RBPs) control mRNA processing, stability, transport, editing, and translation. We recently conducted transcriptome analyses comparing normal (i.e. Read More

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http://dx.doi.org/10.1128/mBio.02687-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355981PMC
January 2019
2 Reads

Observed Colposcopy Practice in US Community-Based Clinics: The Retrospective Control Arm of the IMPROVE-COLPO Study.

J Low Genit Tract Dis 2019 Jan 25. Epub 2019 Jan 25.

Oklahoma Cancer Specialists and Research Institute and University of Oklahoma School of Community Medicine, Tulsa, OH.

Objective: The aim of the study was to characterize colposcopy practice and management of women with cervical abnormalities in US community-based clinics.

Materials And Methods: IMPROVE-COLPO was a 2-arm study of colposcopy patients with an abnormal screening result. The prospective arm recruited women to undergo examination with a commercial digital colposcope. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000454DOI Listing
January 2019
2 Reads

Objective assessment of visual acuity: a refined model for analyzing the sweep VEP.

Doc Ophthalmol 2019 Jan 29. Epub 2019 Jan 29.

Institute for Ophthalmic Research, University of Tuebingen, Elfriede-Aulhorn-Str. 7, 72076, Tuebingen, Germany.

Purpose: The aim of this study was to develop a simple and reliable method for the objective assessment of visual acuity by optimizing the stimulus used in commercially available systems and by improving the methods of evaluation using a nonlinear function, the modified Ricker model.

Methods: Subjective visual acuity in the normal subjects was measured with Snellen targets, best-corrected, and in some cases also uncorrected and with plus lenses (+ 1 D, + 2 D, + 3 D). In patients, subjective visual acuity was measured best-corrected using the Freiburg Visual Acuity Test. Read More

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http://dx.doi.org/10.1007/s10633-019-09672-zDOI Listing
January 2019

Erector spinae plane block as a rescue therapy for uncontrolled pain after laparotomic surgery: A report of two cases.

Saudi J Anaesth 2019 Jan-Mar;13(1):66-68

Department of Medicine - DIMED, Section of Anesthesiology and Intensive Care, University of Padua, Padua, Italy.

The erector spinae plane block (ESP) is a novel interfascial block described in 2016 by Forero. Although it has been used to provide analgesia for planned abdominal and thoracic surgery, it has never been used as a rescue technique for abdominal surgery. Pain control can be a challenge for anaesthesiologists in laparotomic surgery when epidural analgesia is contraindicated. Read More

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http://dx.doi.org/10.4103/sja.SJA_449_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329249PMC
January 2019

Does Resveratrol Play a Role in Decreasing the Inflammation Associated with Contrast Induced Nephropathy in Rat Model?

J Clin Med 2019 Jan 27;8(2). Epub 2019 Jan 27.

Institute of Clinical Medicine, National Yang-Ming University, Taipei 112, Taiwan.

Contrast is widely used in invasive image examinations such as computed tomography (CT) and angiography; however, the risk of contrast-induced nephropathy (CIN) is high. The aim of this study was to investigate the protective effect of resveratrol in a rat model of CIN. Sprague-Dawley rats were divided into four groups: the control group (0. Read More

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http://dx.doi.org/10.3390/jcm8020147DOI Listing
January 2019

Suppression of miR-93-5p inhibits high-risk HPV-positive cervical cancer progression via targeting of BTG3.

Hum Cell 2019 Jan 28. Epub 2019 Jan 28.

Department of Gynecology, Second Hospital of Hebei Medical University, No.215, HePing West Road, Shijiazhuang, 050000, Hebei, China.

This study explores the role of miR-93-5p in high-risk HPV-positive (HR-HPV) cervical cancer by targeting of BTG3. Cervical tissues were collected from 332 patients with conditions of chronic cervicitis (n = 42), low-grade cervical intraepithelial neoplasia (CIN I, n = 51), CIN II (n = 49), CIN III (n = 43), cervical cancer (n = 90), and normal cervical tissues (n = 57). HR-HPV DNA was detected by Hybrid Capture 2, and the expressions of miR-93-5p and BTG3 were determined by qRT-PCR and Western blot. Read More

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http://dx.doi.org/10.1007/s13577-018-00225-1DOI Listing
January 2019

"Keeping You in the Know": The Effect of an Online Nursing Journal Club on Evidence-Based Knowledge Among Rural Registered Nurses.

Authors:
Joyce E DuGan

Comput Inform Nurs 2019 Jan 25. Epub 2019 Jan 25.

Author Affiliation: West Chester University, DuBois, PA.

The purpose of this research study was to promote and evaluate clinical scholarship in rural registered nurses through the dissemination of evidence-based practice findings via the development and implementation of an online nursing journal club. A simple pretest-posttest design was selected to implement this project. Along with descriptive data, survey data were analyzed using a paired t test. Read More

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http://dx.doi.org/10.1097/CIN.0000000000000507DOI Listing
January 2019

Nurses "Seeing Forest for the Trees" in the Age of Machine Learning: Using Nursing Knowledge to Improve Relevance and Performance.

Comput Inform Nurs 2019 Jan 25. Epub 2019 Jan 25.

Author Affiliations: Schools of Nursing (Mr Kwon and Dr Currie) and Population and Public Health (Dr Karim), University of British Columbia; and Centre for Health Evaluation and Outcome Sciences (CHÉOS), Providence Health Care Research Institute (Dr Karim), Vancouver, British Columbia, Canada; School of Nursing and Data Science Institute, Columbia University (Dr Topaz); and Brigham and Women's Health Hospital, Boston, MA (Dr Topaz).

Although machine learning is increasingly being applied to support clinical decision making, there is a significant gap in understanding what it is and how nurses should adopt it in practice. The purpose of this case study is to show how one application of machine learning may support nursing work and to discuss how nurses can contribute to improving its relevance and performance. Using data from 130 specialized hospitals with 101 766 patients with diabetes, we applied various advanced statistical methods (known as machine learning algorithms) to predict early readmission. Read More

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http://dx.doi.org/10.1097/CIN.0000000000000508DOI Listing
January 2019
0.812 Impact Factor

Management and treatment of cervical intraepithelial neoplasia in the Netherlands after referral for colposcopy.

Acta Obstet Gynecol Scand 2019 Jan 28. Epub 2019 Jan 28.

Department of Public Health, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.

Introduction: The aim of this study was to describe trends in diagnosis and treatment of women referred from screening with cervical intraepithelial neoplasia (CIN) in the Netherlands, compare this to national guidelines and identify potential areas for improvement for the new primary high-risk HPV screening program.

Material And Methods: We conducted a population-based cohort study using data from Dutch pathology archive. Women aged 29 to 63 years who took part in the Dutch cervical screening program between 1 January 2005 to 31 December 2014 were selected. Read More

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http://dx.doi.org/10.1111/aogs.13547DOI Listing
January 2019
2 Reads

Improved Particle Swarm Optimization Algorithm Based on Last-Eliminated Principle and Enhanced Information Sharing.

Comput Intell Neurosci 2018 5;2018:5025672. Epub 2018 Dec 5.

College of Instrumentation & Electrical Engineering, Jilin University, Changchun 130061, China.

In this study, an improved eliminate particle swarm optimization (IEPSO) is proposed on the basis of the last-eliminated principle to solve optimization problems in engineering design. During optimization, the IEPSO enhances information communication among populations and maintains population diversity to overcome the limitations of classical optimization algorithms in solving multiparameter, strong coupling, and nonlinear engineering optimization problems. These limitations include advanced convergence and the tendency to easily fall into local optimization. Read More

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http://dx.doi.org/10.1155/2018/5025672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305047PMC
December 2018

Geoffrey: An Automated Schedule System on a Social Robot for the Intellectually Challenged.

Comput Intell Neurosci 2018 2;2018:4350272. Epub 2018 Dec 2.

Institute for Computer Research, University of Alicante, P. O. Box 99. 03080, Alicante, Spain.

The accelerated growth of the percentage of elder people and persons with brain injury-related conditions and who are intellectually challenged are some of the main concerns of the developed countries. These persons often require special cares and even almost permanent overseers that help them to carry out diary tasks. With this issue in mind, we propose an automated schedule system which is deployed on a social robot. Read More

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https://www.hindawi.com/journals/cin/2018/4350272/
Publisher Site
http://dx.doi.org/10.1155/2018/4350272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330830PMC
December 2018
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(At Least) Once in Her Lifetime: Global Cervical Cancer Prevention.

Obstet Gynecol Clin North Am 2019 Mar;46(1):107-123

Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Belfer 1308A, Bronx, NY 10461, USA.

Cervical cancer disproportionately burdens lower-resourced settings, in which nearly 90% of cervical cancer and cervical cancer-related deaths occur. Targeting human papillomavirus (HPV) by prophylactic HPV vaccination in young adolescent girls and HPV-based screening in mid-adult women offers the most cost-effective strategy to reduce cervical cancer burden worldwide and mitigate the health disparities in cervical cancer burden between low-resourced and high-resourced settings. Political and social will, along with the necessary financial investments, will be necessary to realize the opportunity for significant global reductions in the cervical cancer burden. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.09.007DOI Listing