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J Epidemiol Glob Health 2020 12 21;10(4):367-377. Epub 2020 Jul 21.

Department of Industrial Engineering, University of Rome Tor Vergata, Rome, Italy.

The rapid detection of ongoing outbreak - and the identification of causative pathogen - is pivotal for the early recognition of public health threats. The emergence and re-emergence of infectious diseases are linked to several determinants, both human factors - such as population density, travel, and trade - and ecological factors - like climate change and agricultural practices. Several technologies are available for the rapid molecular identification of pathogens [e. Read More

Nat Rev Microbiol 2019 05;17(5):261-263

Istituto Nazionale per le Malattie Infettive "Lazzaro Spallanzani" (National Institute for Infectious diseases "Lazzaro Spallanzani" - IRCCS), Rome, Italy.

Mil Med 2016 11;181(11):e1675-e1684

1st Area Medical Laboratory Building 5116, Bel Air Street, Aberdeen Proving Ground, MD 21005.

Background: The U.S. Army 1 Area Medical Laboratory (1 AML) is currently the only deployable medical CBRNE (Chemical, Biological, Radiological, Nuclear, and Explosives) laboratory in the Army's Forces Command. Read More

Epidemiol Infect 2016 05;144(7):1463-72

International Master Courses in Protection Against CBRNe events,Department of Industrial Engineering and School of Medicine and Surgery,University of Rome Tor Vergata,Italy.

Mathematical modelling is an important tool for understanding the dynamics of the spread of infectious diseases, which could be the result of a natural outbreak or of the intentional release of pathogenic biological agents. Decision makers and policymakers responsible for strategies to contain disease, prevent epidemics and fight possible bioterrorism attacks, need accurate computational tools, based on mathematical modelling, for preventing or even managing these complex situations. In this article, we tested the validity, and demonstrate the reliability, of an open-source software, the Spatio-Temporal Epidemiological Modeler (STEM), designed to help scientists and public health officials to evaluate and create models of emerging infectious diseases, analysing three real cases of Ebola haemorrhagic fever (EHF) outbreaks: Uganda (2000), Gabon (2001) and Guinea (2014). Read More

Virus Res 2015 Dec 8;210:318-26. Epub 2015 Sep 8.

Department of Industrial Engineering, University of Rome Tor Vergata, Rome, Italy; Didactical Board of the International Master Courses in Protection Against CBRNe events, Department of Industrial Engineering and School of Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy.

Among the potential biological agents suitable as a weapon, Ebola virus represents a major concern. Classified by the CDC as a category A biological agent, Ebola virus causes severe hemorrhagic fever, characterized by high case-fatality rate; to date, no vaccine or approved therapy is available. The EVD epidemic, which broke out in West Africa since the late 2013, has got the issue of the possible use of Ebola virus as biological warfare agent (BWA) to come to the fore once again. Read More