BMC Musculoskelet Disord 2022 Apr 12;23(1):352. Epub 2022 Apr 12.
UOC Recupero E Riabilitazione Funzionale, Ambito Territoriale Pisano, ASL Toscana Nordovest, Pisa, Italy.
Background: The advancement of physiopathological knowledge of tendon structures has shown that, in conditions of overload, there is the onset of both degenerative phenomena, such as the production of metalloproteases, apoptosis of tendon cells and neoangiogenesis, and regenerative and protective phenomena, such as the production of IGF-1 and nitric oxide. Tendinopathy results from the imbalance between these two groups of factors, leading to degeneration, weakening, and fissuring of the tendons, with the presence of local pain. The aim of the study was to evaluate the efficacy and tolerability of cetylated fatty acids (CFA) patch formulation in the control of acute localized shoulder pain and recovery of function in patients with tendinopathies. Read More