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Ocul Immunol Inflamm 2021 Jun 14:1-6. Epub 2021 Jun 14.

Department of Ophthalmology, Long School of Medicine, University of Texas Health at San Antonio, San Antonio, Texas, USA.

: To investigate the safety and efficacy of topical erythropoietin for the treatment of scleral necrosis.: This study enrolled eight consecutive patients with scleral necrosis due to previous ocular surgery, rheumatoid arthritis-associated necrotizing anterior scleritis, and thermal and chemical burns. Conventional treatments failed to heal avascular scleral lesions in all eyes. Read More

J Burn Care Res 2021 Jun 12. Epub 2021 Jun 12.

Division of Plastic and Reconstructive Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA.

Introduction: Burn wound depth assessments are an important component of determining patient prognosis and making appropriate management decisions. Clinical appraisal of the burn wound by an experienced burn surgeon is standard of care but has limitations. IR thermography is a technology in burn care that can provide a non-invasive, quantitative method of evaluating burn wound depth. Read More

Ocul Surf 2021 Jun 9;21:178-185. Epub 2021 Jun 9.

Department of Ophthalmology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, 100853, China. Electronic address:

Purpose: To evaluate long-term anatomical and functional outcomes of the MICOF keratoprosthesis to treat end-stage corneal blindness.

Design: Retrospective review of consecutive clinical case series.

Participants: Between October 2000 and October 2015, at the Department of Ophthalmology of Chinese PLA General Hospital (PLAGH), a total of 132 eyes of 131 patients had undergone a MICOF keratoprosthesis implantation. Read More

J Mater Sci Mater Med 2021 Jun 12;32(6):67. Epub 2021 Jun 12.

Department of Paper sciences and engineering, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran.

The effectiveness of tannic acid as antimicrobial and wound healing for burns have been shown for a century; however, uncontrolled target dosage may result in undesirable side-effects. Remarkably, tannic acid polyphenols compounds crosslinked with polymeric materials produce a strong composite containing the beneficial properties of this tannin. However, investigation of the crosslink structure and its antibacterial and regenerative properties are still unknown when using nanocellulose by mechanical defibrillation; additionally, due to the potential crosslink structure with chitosan, its structure can be complex. Read More

Burns 2021 May 30. Epub 2021 May 30.

Department of Hand Surgery, Plastic Surgery and Burns in Linköping University, Sweden; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.

Introduction: As compared to younger adults, older people have a greater risk of domestic accidents, such as burns, and their prognosis is worsened by a diminished physiological ability to face a thermal trauma. The in-hospital mortality is adversely affected by old age and burn size, whereas less is known about the long-term-survival in elderly patients who survive a burn injury. The aim of this study was to investigate if elderly burn patients after discharge from a Swedish National Burn Centre have a shorter remaining life compared to the national population, by using calculated remaining Life Expectancy (rLE). Read More

Burns 2021 Apr 23. Epub 2021 Apr 23.

Department of Pathology and Department of Surgery, University of Wisconsin School of Medicine and Public Health, 5605 MSC 1300 University Avenue Madison, WI 53706, United States.

Objective: This phase 3 study evaluated StrataGraft construct as a donor-site sparing alternative to autograft in patients with deep partial-thickness (DPT) burns.

Methods: Patients aged ≥18 years with 3-49% total body surface area (TBSA) thermal burns were enrolled. In each patient, 2 DPT areas (≤2000cm total) of comparable depth after excision were randomized to either cryopreserved StrataGraft or autograft. Read More

Int J Burns Trauma 2021 15;11(2):115-122. Epub 2021 Apr 15.

Assistant Professor Trauma Surgery, Trauma Centre, AIIMS Rishikesh India.

Background: High voltage (>1000 V) electric injuries (HVEI) are rare, and dreaded due to profound myonecrosis and fatal arrhythmias. Trauma Centres are well equipped for acute and definitive treatment of injuries. Paucity of burn centres in Himalayan belt make trauma centres a prudent choice for management of HVEIs. Read More

Int J Burns Trauma 2021 15;11(2):112-114. Epub 2021 Apr 15.

Department of Burn Surgery, United States Army Institute of Surgical Research Fort Sam Houston, TX, USA.

Freeze branding was first performed in 1966 to identify animals for agricultural purposes, and remains relevant today in veterinary medicine. In contrast, human branding for aesthetics, punishment, identification, and purported medicinal benefits is standardly performed through transfer of thermal energy via heat. Uniquely, this case report documents the first description of freeze branding as a mechanism of injury in humans resulting in a 0. Read More

J Burn Care Res 2021 Jun 5. Epub 2021 Jun 5.

Department of Orthopedic Surgery and Division of Plastic Surgery, University of California Los Angeles, Los Angeles, CA, UCLA Medical Plaza Suite, Los Angeles, CA.

Children are one of the most vulnerable populations to burns, and hands are frequently burned anatomical structures. Restoring function in a severely burned pediatric hand is challenging. We present our experience with pediatric toe-to-thumb transfers for burn reconstruction. Read More

J Emerg Med 2021 Jun 2. Epub 2021 Jun 2.

Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.

Background: Burns are a common condition presenting to the emergency department; the majority are thermal burns. The treatment for thermal burns and chemical burns differs greatly, and prompt recognition of a chemical burn is necessary. An often unrecognized and underestimated type of chemical burn is an alkali burn from wet cement. Read More

World Neurosurg 2021 Jun 1. Epub 2021 Jun 1.

Department of Neurological Surgery, Mayo Clinic, Rochester, MN. Electronic address:

Introduction: We conduct a systematic review and pooled analysis of the literature for outcomes on patients with recurrent glioblastoma (rGBM) undergoing laser interstitial thermal therapy (LITT).

Methods: A literature search was performed to retrieve all studies investigating overall survival, post-procedure survival and progression-free survival outcomes of patients with rGBM undergoing LITT. Statistics were pooled together by meta-analysis of mean using a weighted random-effects (RE) or fixed-effect (FE) model. Read More

BMJ Case Rep 2021 Jun 2;14(6). Epub 2021 Jun 2.

US Army Burn Center, US Army Institute of Surgical Research, Fort Sam Houston, Texas, USA

A 23-year-old man presented to our burn center after sustaining a 62.5% total body surface area burn during a fire performance, in which he applied alcohol-based hand sanitiser to his body and ignited it. The patient underwent 6 operations at this facility and was discharged after 41 days. Read More

Respir Care 2021 Jun 1. Epub 2021 Jun 1.

Service of Neonatology and Pediatric Intensive Care, Department of Pediatrics, University Hospital of Geneva, Geneva, Switzerland.

Background: User errors in managing heated humidifiers (HHs) have been suggested to be a source of nasal burns in newborns treated with nasal CPAP. This study evaluated the risk of burns by reproducing 3 typical errors concerning the use of HHs.

Methods: Six HHs were tested on a bench in a traditional nasal CPAP setup: PMH5000, Aircon (Wilamed); MR730, MR850, MR950 (Fisher & Paykel); and H900 (Hamilton). Read More

J Fungi (Basel) 2021 May 6;7(5). Epub 2021 May 6.

Institute of Systematics and Ecology of Animals of Siberian Branch of the Russian Academy of Science, Frunze Str. 11, 630091 Novosibirsk, Russia.

Ricin-B-lectins (RBLs) have been identified in many groups of organisms, including coleopterans insects, particularly the Colorado potato beetle (LdRBLs). We hypothesized that one of these LdRBLs (LdRBLk) may be involved in the immune response to fungal infections. We performed a theoretical analysis of the structure of this protein. Read More

Materials (Basel) 2021 May 5;14(9). Epub 2021 May 5.

Department of Apparel, Events, and Hospitality Management, Iowa State University, Ames, IA 50011-2100, USA.

In 2017, more than 60,000 firefighters and oilfield-workers injuries and fatalities occurred while they were working under various thermal hazards such as flame, radiant heat, steam, etc., or due to their significant heat stress related discomfort. The majority of these burn injuries and fatalities results from an inadequate protection and comfort provided by firefighters' and oilfield-workers' fire protective polymeric textile materials used in their workwear. Read More

Trop Doct 2021 May 30:494755211019314. Epub 2021 May 30.

Assistant Professor, Division of Trauma Surgery, Department of Surgical Disciplines, Jai Prakash Narayan Apex Trauma Centre, All India Institute of Medical Sciences, New Delhi, India.

In industrial foundries, raw metal is heated almost up to its melting point and then passed through the rolling mill to mould it into a desired shape. Contact with hot machinery or the hot metal can cause severe deep burns. When such thermal injury involves the abdominal wall, complex bowel injury can occur, leading to life-threatening abdominal sepsis. Read More

Stem Cell Res Ther 2021 May 29;12(1):308. Epub 2021 May 29.

Toxicology and Forensic Medicine Department, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511, Egypt.

Background And Aim: Deleterious cutaneous tissue damages could result from exposure to thermal trauma, which could be ameliorated structurally and functionally through therapy via the most multipotent progenitor bone marrow mesenchymal stem cells (BM-MSCs). This study aimed to induce burns and examine the effect of BM-MSCs during a short and long period of therapy.

Material And Methods: Ninety albino rats were divided into three groups: group I (control); group II (burn model), the animals were exposed to the preheated aluminum bar at 100°C for 15 s; and group III (the burned animals subcutaneously injected with BM-MSCs (2×10 cells/ ml)); they were clinically observed and sacrificed at different short and long time intervals, and skin samples were collected for histopathological and immunohistochemical examination and analysis of different wound healing mediators via quantitative polymerase chain reaction (qPCR). Read More

Burns 2020 Jul 11. Epub 2020 Jul 11.

Department of General Surgery, Motahari Burn Research Center, Iran University of Medical Sciences, Tehran, Iran. Electronic address:

Introduction: Although blood transfusion is common in burns, data are lacking in appropriate transfusion thresholds. It has been reported that a restrictive blood transfusion policy decreases blood utilization and improves outcomes in critically ill adults, but the impact of a restrictive blood transfusion policy in burn patients is unclear. We decided to investigate the outcome of decreasing the blood transfusion threshold. Read More

Zhonghua Shao Shang Za Zhi 2021 May;37(5):475-484

Department of Social Work, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

To analyze and discuss the psychological needs of family members of critically ill burn inpatients in semi-closed wards and their related influence factors. A cross-sectional survey was conducted among the 82 burn patients, who met the inclusion criteria and were admitted to the Department of Burns and Plastic Surgery of Ruijin Hospital of Shanghai Jiao Tong University School of Medicine from October 2018 to April 2019, and their family members. A general condition questionnaire of 15 indexes was applied to investigate the general data of burn patients and their family members including cause of burn, gender, age, total burn area, burn depth, burn severity, burn site, and type of medical insurance of patients, kinship with the patients, gender, age, experience of accompanying in intensive care isolation wards, occupation, education level, and monthly income of their family members. Read More

Arthrosc Sports Med Rehabil 2021 Apr 23;3(2):e605-e613. Epub 2021 Feb 23.

Department of Orthopaedic Surgery, Onze Lieve Vrouwe Gasthuis Amsterdam, the Netherlands.

Purpose: To investigate the occurrence of heat-related complications from radiofrequency and electrocautery devices in patients undergoing arthroscopic surgery.

Methods: A systematic review was performed using the PubMed/Medline, Embase, CINAHL (Cumulative Index to Nursing and Allied Health Literature), and Cochrane databases, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. All studies reporting complications after arthroscopy using electrosurgery devices were included. Read More

Am J Transl Res 2021 15;13(4):2499-2510. Epub 2021 Apr 15.

Department of Burn and Plastic Surgery, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health Hangzhou, Zhejiang Province, China.

Objective: The study aims to elucidate the impact of LncRNA HULC in human skin fibroblasts (HSF) after burns in children. HULC might act as endogenous sponges for miR-663b to regulate the gene expression of TLR4.

Methods: This study included 46 children with deep second-degree burns. Read More

J Burn Care Res 2021 May 20. Epub 2021 May 20.

Department of Burns and Plastic Surgery, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics.

The incidence of pediatric treadmill hand friction burns has been increasing every year. The injuries are deeper than thermal hand burns, the optimal treatment remains unclear. This was a retrospective study of children who received surgery for treadmill hand friction burns from January 1, 2015, to December 31, 2019, in a single burn center. Read More

J Burn Care Res 2021 May 20. Epub 2021 May 20.

Department of Plastic, Reconstructive and Hand surgery, Burn Centre for Severe Burn Injuries, Nuremberg Clinics, University Hospital Paracelsus Medical University.

The accurate assessment of burn wounds is challenging but crucial for correct diagnosis and following therapy. The most frequent technique to evaluate burn wounds remains the clinical assessment often subjective depending on the experience of the physician. Hyperspectral Imaging is intended to counteract this subjective diagnosis by an accurate and objective analysis of perfusion parameters. Read More

Ann Transl Med 2021 Apr;9(8):719

Burn Institute, The Fourth Medical Center of the PLA General Hospital, Beijing, China.

Objective: We aimed to review and discuss some of the latest research results related to post-burn pathophysiological changes and provide some clues for future study.

Background: Burns are one of the most common and serious traumas and consist of a series of pathophysiological changes of thermal injury. Accompanied by thermal damage to skin and soft tissues, inflammatory mediators are released in large quantities. Read More

Burns 2021 Apr 20. Epub 2021 Apr 20.

Department of Anesthesiology, University of Kansas Medical Center, Kansas City, KS 66160, USA.

Acute pain is prevalent following burn injury and can often transition to chronic pain. Prolonged acute pain is an important risk factor for chronic pain and there is little preclinical research to address this problem. Using a mouse model of second-degree burn, we investigated whether pre-existing stress influences pain(sensitivity) after a burn injury. Read More

J Orthop Case Rep 2020 May-Jun;10(3):50-52

Department of Paediatric Orthopaedics, Sancheti Institute for Orthopaedics and Rehabilitation, Pune, Maharashtra, India.

Introduction: Ponseti casting method is the gold standard for the management of congenital talipes equinovarus in neonates, which consists of weekly manipulation and serial casting. Using oscillatory saw for cast removal is user-dependant and has been fraught with complications consisting of saw burns, thermal abrasions, anxiety, and fear of the saw (especially in children). The aim of this article is to describe our technique of cast removal using visual media format. Read More

Medicina (Kaunas) 2021 Apr 15;57(4). Epub 2021 Apr 15.

Department of Surgery, University of Texas Medical Branch at Galveston, Galveston, TX 77550, USA.

Thermal injuries have been a phenomenon intertwined with the human condition since the dawn of our species. Autologous skin translocation, also known as skin grafting, has played an important role in burn wound management and has a rich history of its own. In fact, some of the oldest known medical texts describe ancient methods of skin translocation. Read More

J Burn Care Res 2021 Apr 29. Epub 2021 Apr 29.

University of Massachusetts Medical School, Division of Plastic Surgery.

Burn depth is a critical factor in determining the healing potential of a burn as the extent of injury ultimately guides overall treatment. Visible Light Hyperspectral Imaging is an FDA-approved, non-invasive, and non-contrast imaging technology that uses light waves within the visible spectrum to evaluate skin and superficial soft tissue perfusion. In this case report, Visible Light Hyperspectral Imaging was used to evaluate a 37-year-old male who presented to the Emergency Department with a thermal burn of the trunk, back, and right upper extremity. Read More

Environ Manage 2021 Jul 29;68(1):117-125. Epub 2021 Apr 29.

Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, 19 Chlorine Gardens, Belfast, BT9 5DL, Northern Ireland, UK.

Suppression of established populations of invasive alien species can be a complex and expensive process, which is frequently unsuccessful. The Asian clam, Corbicula fluminea (Müller, 1774), is considered a high impact invader that can adversely alter freshwater ecosystems and decrease their socioeconomic value. To date, C. Read More