93,551 results match your criteria Burns Thermal
Travel Med Infect Dis 2018 Dec 12. Epub 2018 Dec 12.
Academic Department of Military Medicine, Medical Directorate, Defence Medical Services, Birmingham, UK.
Background: . Diarrhea is a well-established problem in travellers, with military personnel at especially high risk. This study aimed to characterise the spectrum of pathogens causing diarrhea in UK military personnel in South Sudan, and assess the utility of culture-independent testing for etiology and antimicrobial resistance in a logistically challenging and austere environment. Read More
Gene 2018 Dec 12. Epub 2018 Dec 12.
Department of Thoracic Oncology, First Affiliated Hospital of Xi'an Medical College, Xi'an 710032, Shaanxi Province, PR China. Electronic address:
Background: Accumulating studies have reported that GLUT1 is aberrantly expressed in lung cancer; nevertheless, the clinicopathologic significance and the prognostic role of GLUT1 still remain controversial. The aim of this meta-analysis was to identify the clinicopathologic and prognostic implications of the GLUT1 expression in lung cancer patients.
Materials And Methods: Databases with literature published in English, including Cochrane Library, Embase, Web of Science, and PubMed, and the China National Knowledge Infrastructure (CNKI) and WanFang database in Chinese were searched comprehensively for relevant studies in August 2017. Read More
Arch Biochem Biophys 2018 Dec 12. Epub 2018 Dec 12.
Department of Burns and Cutaneous Surgery, Xijing Hospital, The Fourth Military Medical University, 127 Changle West Road, Xi'an, Shaanxi, 710032, China. Electronic address:
Severe inflammation may lead to multiple organs dysfunction syndrome, which has a high mortality. MicroRNA is found participated in this process. In this study we developed a lipopolysaccharide-induced inflammation cell model on macrophages and a lipopolysaccharide-induced inflammation mouse model. Read More
Presse Med 2018 Dec 11. Epub 2018 Dec 11.
Hôpital Habib Bourguiba de Sfax, service de chirurgie plastique réparatrice et esthétique, rue Al Firdaws, Sfax Tunisie.
Biomed Pharmacother 2019 Jan 9;109:1268-1275. Epub 2018 Nov 9.
Department of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China. Electronic address:
Bone marrow mesenchymal stem cells (BMSCs) possess promising therapeutic effects and have been considered as a highly desirable agent for tissue injury treatment. However, little survived cells after transplanting due to severe relocated conditions (characterized by prolonged hypoxia and oxidative stress) lead to hampered benefits of BMSCs-based cell therapy. Curcumin, a natural dietary product, has attracted increasing attention owing to its profound pharmacologic properties. Read More
J Environ Manage 2018 Dec 11;233:1-11. Epub 2018 Dec 11.
Waterway Ecosystem Research Group, School of Ecosystem and Forest Science, The University of Melbourne, Burnley, Victoria, 3121, Australia.
The potential for catchment-scale stormwater control measures (SCMs) to mitigate the impact of stormwater runoff issues and excess stormwater volume is increasingly recognised. There is, however, limited understanding about their potential in reducing in-channel disturbance and improving hydraulic conditions for stream ecosystem benefits. This study investigates the benefits that SCM application in a catchment have on in-stream hydraulics. Read More
Ophthalmic Plast Reconstr Surg 2018 Dec 7. Epub 2018 Dec 7.
The Hansjörg Wyss Department of Plastic Surgery and.
Purpose: Periorbital injuries are common in face transplantation (FT) candidates. It is therefore essential that the ophthalmologist play a central role in the multidisciplinary treatment of these patients. In this study, the authors perform a comprehensive review of all procedures involving periorbital components, provide an update for the ophthalmology community regarding the current state of the field, and present 2 cases. Read More
Isr Med Assoc J 2018 Dec;20(12):784-785
Department of Plastic Surgery and Burns, Rabin Medical Center (Beilinson Campus), Petah Tikva, Israel.
Isr Med Assoc J 2018 Dec;20(12):737-740
Department of Plastic and Reconstructive Surgery, Rambam Health Care Campus, affiliated with Technion-Israel Institute of Technology, Haifa, Israel.
Background: Pneumonia is a major cause of morbidity and mortality in burn patients with inhalation injuries. An increased risk of pneumonia has been demonstrated in trauma and burn patients urgently intubated in the field vs. emergency departments (EDs). Read More
J Paediatr Child Health 2018 Dec 12. Epub 2018 Dec 12.
Australian Institute of Health Innovation, Macquarie University, Sydney, New South Wales, Australia.
Aim: Globally, burns remain a significant public health issue that disproportionately affect young children. The current study examines the 10-year epidemiological profile of burn hospitalisations, hospital treatment cost and health outcomes by age group for children ≤16 years in Australia.
Methods: National, population-based, linked hospital and mortality data from 1 July 2002 to 30 June 2012 were used to identify burn-related hospitalisations. Read More
Drug Alcohol Rev 2018 Dec 12. Epub 2018 Dec 12.
National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.
Introduction And Aims: Direct acting antiviral (DAA) treatment can reduce hepatitis C virus (HCV) infection incidence and mortality, although large scale uptake of these treatments is necessary to achieve those reductions. Targeting people who inject drugs (PWID) will be crucial to achieve the necessary reductions. Previously, treatment uptake has been very low (1-2%) among PWID, but these new DAAs have been subsidised in Australia since March 2016. Read More
J Biomed Mater Res A 2018 Dec 10. Epub 2018 Dec 10.
Key Laboratory, Department of Urology and Andrology, the Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
There is currently no optimal scaffold for the transplantation of limbal stem cells (LSCs) to induce corneal reconstruction after corneal alkali burns. This study attempts to fabricate a novel in situ Alginate-Chitosan hydrogel (ACH) for LSCs transplantation. Sodium alginate dialdehyde (SAD), a biological cross-linker, was prepared by periodate-mediated sodium alginate oxidization. Read More
BMC Syst Biol 2018 Dec 14;12(Suppl 7):118. Epub 2018 Dec 14.
National Medical Centre of Colorectal Disease, The Third Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210001, China.
Background: Bladder cancer (BC) is the most common cancer of the urinary bladder and upper tract, in which the clinical management is limited. AURKA (aurora kinase A) has been identified as an oncogene in cancer development; however, its potential role and underlying mechanisms in the progression of BC remain unknown.
Results: In this study, we evaluated Aurora kinase A (AURKA) expression in patient samples by performing gene expression profiling, and found that AURKA expression levels were significantly higher in BC tissues than in normal tissues. Read More
BMC Syst Biol 2018 Dec 14;12(Suppl 7):119. Epub 2018 Dec 14.
Department of Pharmacy, Shanghai University of Medicine & Health Sciences, Shanghai, 201318, China.
Background: Accumulation of amyloid β-peptide (Aβ) is implicated in the pathogenesis and development of Alzheimer's disease (AD). Neuron-enriched miRNA was aberrantly regulated and may be associated with the pathogenesis of AD. However, regarding whether miRNA is involved in the accumulation of Aβ in AD, the underlying molecule mechanism remains unclear. Read More
Nutr Hosp 2018 Apr 3;35(Spec no2):13-17. Epub 2018 Apr 3.
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The term "micronutrients" include vitamins and trace elements. Their recommended intakes in enteral formulas has been adhered to RDI/RDA and, in addition, their content is regulated in the European Union. However, deficiencies in micronutrients has been reported in specific patient groups under enteral nutrition (EN) in the last years. Read More
Phys Rev Lett 2018 Nov;121(22):221802
University of Wisconsin, Madison, Wisconsin, USA.
The first evidence of events consistent with the production of a single top quark in association with a photon is reported. The analysis is based on proton-proton collisions at sqrt[s]=13 TeV and recorded by the CMS experiment in 2016, corresponding to an integrated luminosity of 35.9 fb^{-1}. Read More
J Cardiol Cases 2016 Oct 14;14(4):100-102. Epub 2016 Jun 14.
Queens Medical Center, University of Hawaii John A Burns School of Medicine, Honolulu, HI, USA.
We present a case of a 56-year-old man with history of coronary artery disease and prior two coronary bypass surgeries, who presented with chronic chest pain and was found to have a fractured sternal wire that migrated through the right ventricle and embolized to the right lower pulmonary artery without evident hemodynamic consequences. The sternal wire migration process, in part due to patient's poor medical compliance, was captured on serial computed tomography scans over a period of several years. < Recognize potential sternotomy complications on imaging. Read More
Aesthetic Plast Surg 2018 Dec 13. Epub 2018 Dec 13.
Department of Plastic Surgery and Burns Treatment, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark.
Front Immunol 2018 27;9:2757. Epub 2018 Nov 27.
Center for Neuroregeneration, Houston Methodist Research Institute, Houston, TX, United States.
The secondary injury cascade that is activated following traumatic brain injury (TBI) induces responses from multiple physiological systems, including the immune system. These responses are not limited to the area of brain injury; they can also alter peripheral organs such as the intestinal tract. Gut microbiota play a role in the regulation of immune cell populations and microglia activation, and microbiome dysbiosis is implicated in immune dysregulation and behavioral abnormalities. Read More
Eye (Lond) 2018 Dec 13. Epub 2018 Dec 13.
Department of Ophthalmology, Bolton Hospitals NHS Foundation Trust, Bolton, UK.
Objective: To explore self-inflicted retinal burns from laser pointers in children.
Methods: Literature review of laser pointer retinal injuries in childhood and online survey of UK Consultant Ophthalmologists. A cohort of local children with self-inflicted injury is described. Read More
Burns 2018 Dec 10. Epub 2018 Dec 10.
Department of Pharmacy, The Ohio State University Wexner Medical Center, Columbus, OH, United States. Electronic address:
The benefits of oxandrolone in burn patients has led to its accepted use in the burn care community, however details regarding the most common adverse effect, transaminitis, remains unclear. The purpose of this study was to determine the incidence of transaminitis in patients with burn injury and identify risk factors associated with the development of transaminitis. This single-center, retrospective risk factor analysis compared burn patients on oxandrolone with and without the development of transaminitis, defined as any aspartate aminotransferase or alanine aminotransferase value >100mg/dL. Read More
Burns 2018 Dec 10. Epub 2018 Dec 10.
Monash Alfred Psychiatry Research Centre, The Alfred and Monash University Central Clinical School, Australia.
Background: A high prevalence of self-inflicted burn injury is noted in severe burn injury. It remains unclear as to whether gender and past psychiatric history impact upon whether injury is self-inflicted and the outcomes.
Aims: Review the psychiatric history of patients treated in a statewide burn service following severe burn injury and determine whether psychiatric history, extent of burn and mortality are impacted by gender and whether the injury was self-inflicted. Read More
Burns 2018 Dec 10. Epub 2018 Dec 10.
Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong. Electronic address:
Background: Vascularity is an important parameter closely associated with the scar maturation. Reliable and accurate measurement of vascularity helps to monitor the scar change and adopt targeted interventions to prevent excessive scarring and achieve promising outcomes. However, there is no consensus on the assessment tools for the vascularity measurement in scars. Read More
Burns 2018 Dec 10. Epub 2018 Dec 10.
Institute of Applied Health Research, University of Birmingham, Birmingham, UK. Electronic address:
Introduction: For severe burns patient care presents a considerable challenge, necessitating an integrated multi-disciplinary approach that utilises a range of treatments. The period of care post-discharge can be lengthy and complex, and include scar management, occupational and physiotherapies, psychological support, and further surgery. How successfully the patient negotiates this complex care regimen is critical to their long-term recovery and in doing so they would appear to employ approaches recognised as "self-management" in other chronic conditions. Read More
Clin Epigenetics 2018 Dec 13;10(1):155. Epub 2018 Dec 13.
Department of Psychiatry, Yale School of Medicine, 300 George Street, 950 Campbell Ave, West Haven, New Haven, CT, 06511, USA.
Background: The effects of tobacco smoking on epigenome-wide methylation signatures in white blood cells (WBCs) collected from persons living with HIV may have important implications for their immune-related outcomes, including frailty and mortality. The application of a machine learning approach to the analysis of CpG methylation in the epigenome enables the selection of phenotypically relevant features from high-dimensional data. Using this approach, we now report that a set of smoking-associated DNA-methylated CpGs predicts HIV prognosis and mortality in an HIV-positive veteran population. Read More
Scand J Trauma Resusc Emerg Med 2018 Dec 13;26(1):105. Epub 2018 Dec 13.
Helsinki Burn Centre, Department of Plastic Surgery, Helsinki University Hospital and University of Helsinki, PO. Box 800, FI-00029 HUS, Helsinki, Finland.
Background: Acute kidney injury (AKI) is a common complication in severe burns and can lead to significantly poorer outcomes. Although the prognosis has improved in recent decades, the mortality of AKI remains considerable. We investigated the factors that increase the risk of AKI and death after severe burn injury. Read More
Nutr Hosp 2018 Apr 3;0(0):13-17. Epub 2018 Apr 3.
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The term "micronutrients" include vitamins and trace elements. Their recommended intakes in enteral formulas has been adhered to RDI/RDA and, in addition, their content is regulated in the European Union. However, deficiencies in micronutrients has been reported in specific patient groups under enteral nutrition (EN) in the last years. Read More
Int J Environ Res Public Health 2018 Dec 7;15(12). Epub 2018 Dec 7.
Department of Health, Kinesiology, and Recreation, University of Utah, Salt Lake City, UT 84112, USA.
The purpose of this study was to examine the impact of summer breaks on the body composition and cardiovascular fitness of elementary school children who participated in a multi-year school-based physical activity intervention. Participants were 404 children who had their height and weight measured and completed the Progressive Aerobic Cardiovascular Endurance Run (PACER) during physical education classes at the beginning and end of the school year for three consecutive years. To examine the effects of time on health-related fitness data, general linear mixed effects models were employed. Read More
MMWR Morb Mortal Wkly Rep 2018 Dec 14;67(49):1369-1371. Epub 2018 Dec 14.
Influenza Division, National Center for Immunization and Respiratory Diseases, CDC.
Influenza activity in the United States was low during October 2018, and, although it increased slowly during November, activity remains low across most of the country.* During the week ending December 1, 2018, the percentage of outpatient visits for influenza-like illness (ILI) was equal to the national baseline (Figure) and was at or slightly above the region-specific baseline in four of the 10 U.S. Read More
Med Sci Monit 2018 Dec 13;24:9032-9044. Epub 2018 Dec 13.
Institute of Burns, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China (mainland).
BACKGROUND Hedgehog (Hh) signaling pathway-related genes have important roles in several physiological and disease processes that involve cell proliferation. Long non-coding region RNAs (lncRNAs) have a regulatory role on gene expression. Keloid is characterized by excessive proliferation of scar tissue following trauma. Read More
Comput Inform Nurs 2018 Dec 12. Epub 2018 Dec 12.
Author Affiliations: School of Nursing, University of Nevada, Las Vegas (Dr Serafica); John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu (Dr Inouye); School of Nursing, Johns Hopkins University, Baltimore, MD (Dr Lukkahatai); School of Nursing & Dental Hygiene, University of Hawaii at Manoa, Honolulu, (Dr Braginsky); and Department of Kinesiology and Exercise Science (Dr Pacheco) and School of Nursing (Dr Daub), University of Hawaii at Hilo.
The purpose of this study was to explore the barriers to and needs for using mobile health technology to assist low-income Asian American and Pacific Islander participants living in rural Hawaii in their healthcare. Three focus groups consisting of patients, family support/significant others, and providers (N = 19) were conducted to assess the unique needs of low-income Asian American and Pacific Islander patients in rural Hawaii. The electronic health literacy scale was also used among participants in the patients and family support/significant other groups. Read More
J Appl Physiol (1985) 2018 Dec 13. Epub 2018 Dec 13.
Director, Bone & Joint Injury Prevention & Rehabilitation Center, University of Michigan, United States.
Step frequency (SF) in running has received substantial interest from researchers, coaches, therapists, and runners. It has been widely studied in controlled settings, but no study has measured it continuously in elite-level competition. The current study used wrist-based accelerometers in consumer-grade watches to monitor SF and SF variability of competitors in the 2016 100-km World Championship road race. Read More
Oncol Rep 2018 Oct 9. Epub 2018 Oct 9.
Cell Biology Laboratory, State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, P.R. China.
It is generally known that glioblastoma is the most common primary malignant brain tumor and that it is highly aggressive and deadly. Although surgical and pharmacological therapies have made long‑term progress, glioblastoma remains extremely lethal and has an uncommonly low survival rate. Therefore, further elucidation of the molecular mechanisms of glioblastoma initiation and its pathological processes are urgent. Read More
J Glob Health Rep 2018 6;2. Epub 2018 Jul 6.
John A. Burns School of Medicine, Honolulu, Hawaii, USA.
Background: Non-invasive, self-collection sampling methods for human papillomavirus (HPV) DNA detection have the potential to address logistical and cultural barriers to Pap screening, particularly in under resourced settings such as Yap state in the Federated States of Micronesia - a population with low levels of screening and high incidence of cervical cancer.
Methods: A randomized controlled trial was conducted among adult women in Yap to compare cervical HPV DNA in self-collected urine and clinician-collected liquid cytology. Adult women aged 21-65 (n=217) were randomized by the order of sample collection. Read More
Exp Ther Med 2018 Dec 18;16(6):4429-4436. Epub 2018 Sep 18.
Department of Burns and Plastic Surgery, The Drum Tower Clinical College of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.
New collagen sponge scaffold (NCSS) combined with adipose-derived stem cells (ADSCs) in the repair of full-thickness skin wound in nude mice was investigated. Human ADSCs were extracted via enzyme digestion; NCSS materials were prepared using modified method; the tissue-engineered skin substitute was constructed using ADSCs combined with NCSS. Two 10 mm full-thickness skin wounds were designed on the back of 24 female nude mice, respectively. Read More
Front Neurol 2018 13;9:959. Epub 2018 Nov 13.
Department of Radiation Oncology, Mayo Clinic, Jacksonville, FL, United States.
Stereotactic radiosurgery (SRS) is increasingly utilized to treat the resection cavity following resection of brain metastases and recent randomized trials have confirmed postoperative SRS as a standard of care. Postoperative SRS for resected brain metastases improves local control compared to observation, while also preserving neurocognitive function in comparison to whole brain radiation therapy (WBRT). However, even with surgery and SRS, rates of local recurrence at 1 year may be as high as 40%, especially for larger cavities, and there is also a known risk of leptomeningeal disease after surgery. Read More
BMC Obes 2018 3;5:41. Epub 2018 Dec 3.
1Department of Human Nutrition, Food and Animal Sciences, College of Tropical Agriculture and Human Resources, University of Hawai'i at Mānoa. Agricultural Sciences 216, 1955 East-West Rd, Honolulu, HI 96822 USA.
Background: Excessive gestational weight gain and rapid infancy weight gain (RIWG) are associated with increased susceptibility to childhood obesity. Since low-income and minority children are particularly at risk, investigation of the associations between gestational weight gain and rate of infancy weight gain may inform childhood obesity prevention. This study investigated the associations between gestational weight gain and rate of infancy weight gain during the first four to six months postpartum in participants from the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) in Hawai'i and Puerto Rico. Read More
Front Psychiatry 2018 19;9:578. Epub 2018 Nov 19.
St Vincent's Hospital, Fitzroy, VIC, Australia.
The inability to distinguish clearly between methamphetamine-related psychosis and schizophrenia has led to the suggestion that "methamphetamine psychosis" does not represent a distinct diagnostic entity but rather that the drug has triggered a vulnerability to schizophrenia. We tested this possibility by exploring the latent class structure of psychotic symptoms amongst people who use the drug and examining how these latent symptom profiles correspond to a diagnosis of schizophrenia. Latent class analysis was carried out on the lifetime psychotic symptoms of 554 current methamphetamine users, of whom 40 met the DSM-IV criteria for schizophrenia. Read More
Clin J Pain 2018 Dec 11. Epub 2018 Dec 11.
The University of Queensland, School of Nursing, Midwifery and Social Work, St Lucia, QLD, Australia, 4072.
Objectives: The review article was designed to assess the effectiveness of regional anesthesia, specifically peripheral nerve blocks, in the treatment of burn pain; with noting of clinical indications and contraindications for peripheral nerve block application, along with discussion of evidence-based analgesic strategies for providing improved, comprehensive burn pain management.
Methods: A search of relevant literature was performed using CINAHL, PubMed, EMBASE, Web of Science and SCOPUS with a publication date between January 2005 and December 2017.
Results: The search yielded ten results that met criteria. Read More
Trauma Surg Acute Care Open 2018 5;3(1):e000247. Epub 2018 Nov 5.
Riverside University Health System Medical Center and Loma Linda University School of Medicine, Riverside, California, USA.
Background: The National Trauma Data Bank (NTDB) has served as a global benchmark for trauma care quality and outcomes. Herein, we compared patient characteristics, trauma management, and outcomes between Japanese emergency and critical care centers and US level 1 trauma centers using the Japanese Trauma Data Bank (JTDB) and NTDB.
Methods: A retrospective cohort matching (1:1) study was performed. Read More
J Am Assoc Lab Anim Sci 2018 Dec 11. Epub 2018 Dec 11.
The typical daily water intake of common marmosets (Callithrix jacchus) in a research setting has not been well characterized.Because these New World primates are in demand as animal models for neurobehavioral experiments, which can include the potential use of fluid regulation for training, veterinary and research staff need to understand how marmosets keep hydrated under normal circumstances. In the current study, we measured the water consumption of older (age, 5 to 12 y; n = 11) and younger (age, 1 to 2 y; n = 11) marmosets every 3 h during the 12-h light phase in 2 different months (January and July). Read More
Eur J Pharmacol 2018 Dec 8. Epub 2018 Dec 8.
Centre of Biotechnology, Silesian University of Technology, Gliwice, Poland; LinkoCare Life Sciences AB, Sweden; Centre de Biophysique Moléculaire, UPR4301 CNRS CS80054, Rue Charles Sadron, 45071 Orleans cedex 2, France.
The latest findings indicate the huge therapeutic potential of stem cells in regenerative medicine, including the healing of chronic wounds. Main stem cell types involved in wound healing process are: epidermal and dermal stem cells, mesenchymal stem cells (MSCs), endothelial progenitor cells (EPCs) and hematopoietic stem cells (HSCs). In the therapy of chronic wounds, they can be administrated either topically or using different matrix like hydrogels, scaffolds, dermal substitutes and extracellular matrix (ECM) derivatives. Read More
Pediatr Blood Cancer 2018 Dec 10:e27575. Epub 2018 Dec 10.
Discipline of Paediatrics, School of Women's and Children's Health, Faculty of Medicine, UNSW Sydney, New South Wales, Australia.
Colorectal Dis 2018 Dec 10. Epub 2018 Dec 10.
Imperial College London, Department of Surgery and Cancer, St Mary's Hospital Campus, Praed Street, W2 1NY.
Aim: By understanding the reasons for delays in adjuvant chemotherapy (AC) after colonic resection, there is the potential to improve patient outcome. The aim of this study is to determine the extent and impact of complications post hospital discharge on AC delays.
Method: The study cohort included patients who had a colorectal cancer resection in HES, with linkage to primary care data provided by CPRD. Read More
J Appl Clin Med Phys 2018 Dec 7. Epub 2018 Dec 7.
Department of Oncology Physics, Edinburgh Cancer Centre, Western General Hospital, Edinburgh, UK.
Background: Independent verification of the dose delivered by complex radiotherapy can be performed by electronic portal imaging device (EPID) dosimetry. This paper presents 5-yr EPID in vivo dosimetry (IVD) data obtained using the Dosimetry Check (DC) software on a large cohort including breast, lung, prostate, and head and neck (H&N) cancer patients.
Material And Methods: The difference between in vivo dose measurements obtained by DC and point doses calculated by the Eclipse treatment planning system was obtained on 3795 radiotherapy patients treated with volumetric modulated arc therapy (VMAT) (n = 842) and three-dimensional conformal radiotherapy (3DCRT) (n = 2953) at 6, 10, and 15 MV. Read More
Int Urol Nephrol 2018 Dec 7. Epub 2018 Dec 7.
Department of Endocrinology, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Chongqing, 400038, China.
Purpose: To assess the role of serum pigment epithelium-derived factor (PEDF) in the occurrence and development of proteinuria and renal dysfunction and determine its relevant signaling pathway.
Methods: We analyzed serum PEDF, creatinine, the urinary albumin-to-creatinine ratio, and renal morphology of normal or streptozotocin (STZ)-induced diabetic mice, before and after treatment with PEDF. In vitro, podocytes were stimulated with PEDF under normal or high-glucose conditions; permeability was measured by the transwell assay with fluorescein isothiocyanate (FITC)-dextran; and F-actin cytoskeleton was analyzed by phalloidin staining. Read More
Forensic Sci Med Pathol 2018 Dec 7. Epub 2018 Dec 7.
Institute of Forensic Medicine, University of Belgrade - School of Medicine, 31a Deligradska str, Belgrade, 11000, Serbia.
Fat embolism is markedly underdiagnosed, even though it is a well-known phenomenon following fractures of the long bones, injury to subcutaneous fat tissue, rupture of a fatty liver, surgical operations on fatty tissues, septicemia, burns and barotrauma. Forensic pathologists tend to "simplify" autopsy report conclusion in cases with multiple injuries where fat embolism and exsanguination could be considered to be the concomitant causes of death. Herein we present a case of 24-year-old male who was beaten with a metal rod by several persons. Read More
Inj Epidemiol 2018 Dec 10;5(1):44. Epub 2018 Dec 10.
Faculty of Science and Engineering, Macquarie University, Sydney, Australia.
Background: Game of Thrones is a popular television series known for its violent and graphic portrayal of the deaths of its characters. This study aimed to examine the mortality and survival of important characters in Game of Thrones.
Methods: Important characters appearing in Seasons 1 to 7 of Game of Thrones were included, and data on sociodemographic factors, time to death, and circumstances of death were recorded. Read More
Acad Psychiatry 2018 Dec 10. Epub 2018 Dec 10.
Stanford University, Stanford, USA.