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    Fabrication of a Biodegradable Implant with Tunable Characteristics for Bone Implant Applications.
    Biomacromolecules 2017 May 23. Epub 2017 May 23.
    The University of Sydney , School of Chemical and Biomolecular Engineering, Sydney, 2006, Australia.
    Biodegradable polymers are appealing material for the manufacturing of surgical implants as such implants break down in vivo, negating the need for a subsequent operation for removal. Many biocompatible polymers produce acidic breakdown products that can lead to localized inflammation and osteolysis. This study assesses the feasibility of fabricating implants out of poly(propylene carbonate) (PPC)-starch that degrades into CO2 and water. Read More

    Measurement of prompt and nonprompt [Formula: see text] production in [Formula: see text] and [Formula: see text] collisions at [Formula: see text].
    Eur Phys J C Part Fields 2017 27;77(4):269. Epub 2017 Apr 27.
    University of Wisconsin-Madison, Madison, WI USA.
    This paper reports the measurement of [Formula: see text] meson production in proton-proton ([Formula: see text]) and proton-lead ([Formula: see text]) collisions at a center-of-mass energy per nucleon pair of [Formula: see text] by the CMS experiment at the LHC. The data samples used in the analysis correspond to integrated luminosities of 28[Formula: see text] and 35[Formula: see text] for [Formula: see text] and [Formula: see text] collisions, respectively. Prompt and nonprompt [Formula: see text] mesons, the latter produced in the decay of [Formula: see text] hadrons, are measured in their dimuon decay channels. Read More

    Suppression and azimuthal anisotropy of prompt and nonprompt [Formula: see text] production in PbPb collisions at [Formula: see text][Formula: see text].
    Eur Phys J C Part Fields 2017 19;77(4):252. Epub 2017 Apr 19.
    University of Wisconsin-Madison, Madison, WI USA.
    The nuclear modification factor [Formula: see text] and the azimuthal anisotropy coefficient [Formula: see text] of prompt and nonprompt (i.e. those from decays of b hadrons) [Formula: see text] mesons, measured from PbPb and pp collisions at [Formula: see text] [Formula: see text] at the LHC, are reported. Read More

    Measurement of the WZ production cross section in pp collisions at [Formula: see text] and 8[Formula: see text] and search for anomalous triple gauge couplings at [Formula: see text].
    Eur Phys J C Part Fields 2017 12;77(4):236. Epub 2017 Apr 12.
    University of Wisconsin-Madison, Madison, WI USA.
    The WZ production cross section is measured by the CMS experiment at the CERN LHC in proton-proton collision data samples corresponding to integrated luminosities of 4.9[Formula: see text] collected at [Formula: see text], and 19.6[Formula: see text] at [Formula: see text]. Read More

    Fatal Ingestion of Chlumsky Disinfectant Solution.
    J Forensic Sci 2017 May 16. Epub 2017 May 16.
    Department of Anatomy, Faculty of Medicine, Masaryk University, CZ-625 00, Brno, Czech Republic.
    A 32-year-old pregnant woman in the 25th week of pregnancy underwent oral glucose tolerance screening at the diabetologist's. Later that day, she was found dead in her apartment possibly poisoned with Chlumsky disinfectant solution (solutio phenoli camphorata). An autopsy revealed chemical burns in the digestive system. Read More

    SABRE hyperpolarisation of vitamin B3 as a function of pH.
    Chem Sci 2017 Mar 7;8(3):2257-2266. Epub 2016 Dec 7.
    Centre for Hyperpolarisation in Magnetic Resonance , Department of Chemistry , University of York , YO10 5NY , York , UK . Email:
    In this work we describe how the signal enhancements obtained through the SABRE process in methanol-d4 solution are significantly affected by pH. Nicotinic acid (vitamin B3, NA) is used as the agent, and changing pH is shown to modify the level of polarisation transfer by over an order of magnitude, with significant improvements being seen in terms of the signal amplitude and relaxation rate at high pH values. These observations reveal that manipulating pH to improve SABRE enhancements levels may improve the potential of this method to quantify low concentrations of analytes in mixtures. Read More

    Antibacterial efficacy of poly(vinyl alcohol) composite nanofibers embedded with silver-anchored silica nanoparticles.
    J Biomed Mater Res B Appl Biomater 2017 May 15. Epub 2017 May 15.
    Nano Fusion Technology Research Lab, Division of Frontier Fibers, Institute for Fiber Engineering (IFES), Interdisciplinary Cluster for Cutting Edge Research (ICCER), Shinshu University 3-15-1, Tokida, Ueda, Nagono, 386-8567, Japan.
    Silver has been widely used as an effective antibacterial agent especially for treating burns and wounds. However, release of silver from materials often arouse side effects due to toxicity of silver towards mammalian cells. Argyria and argyrosis are well known problems of acute toxicity of silver towards human body. Read More

    Relative Modification of Prompt ψ(2S) and J/ψ Yields from pp to PbPb Collisions at sqrt[s_{NN}]=5.02  TeV.
    Phys Rev Lett 2017 Apr 20;118(16):162301. Epub 2017 Apr 20.
    University of Wisconsin - Madison, Madison, Wisconsin, USA.
    The relative modification of the prompt ψ(2S) and J/ψ yields from pp to PbPb collisions, at the center-of-mass energy of 5.02 TeV per nucleon pair, is presented. The analysis is based on pp and PbPb data samples collected by the CMS experiment at the LHC in 2015, corresponding to integrated luminosities of 28. Read More

    Phase 1/2 study of rilotumumab (AMG 102), a hepatocyte growth factor inhibitor, and erlotinib in patients with advanced non-small cell lung cancer.
    Cancer 2017 May 4. Epub 2017 May 4.
    Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota.
    Background: Activation of the mesenchymal-epidermal transition factor (MET) tyrosine kinase and its ligand, hepatocyte growth factor (HGF), is implicated in resistance to epidermal growth factor receptor (EGFR) inhibitors. In this phase 1/2 trial, rilotumumab (an anti-HGF antibody) combined with erlotinib was evaluated in patients with metastatic, previously treated non-small cell lung cancer.

    Methods: In phase 1, a dose de-escalation design was adopted with rilotumumab starting at 15 mg/kg intravenously every 3 weeks and oral erlotinib 150 mg daily. Read More

    Assessing the Efficacy of First-Aid Measures in Physalia sp. Envenomation, Using Solution- and Blood Agarose-Based Models.
    Toxins (Basel) 2017 Apr 26;9(5). Epub 2017 Apr 26.
    Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI 96813, USA.
    Stings from the hydrozoan species in the genus Physalia cause intense, immediate skin pain and elicit serious systemic effects. There has been much scientific debate about the most appropriate first aid for these stings, particularly with regard to whether vinegar use is appropriate (most current recommendations recommend against vinegar). We found that only a small percentage (≤1. Read More

    Toxicity resulting from exposure to oven cleaners as reported to the UK National Poisons Information Service (NPIS) from 2009 to 2015.
    Clin Toxicol (Phila) 2017 Apr 26:1-7. Epub 2017 Apr 26.
    a NPIS (Birmingham Unit) , City Hospital , Birmingham , UK.
    Introduction: Oven cleaning products contain corrosive substances, typically sodium or potassium hydroxide.

    Objective: To determine the reported toxicity from exposure to oven cleaning products.

    Methods: Telephone enquiries to the UK National Poisons Information Service regarding oven cleaning products were analysed retrospectively for the period January 2009 to December 2015. Read More

    Myths on Chemical Burns in the Diaper Area.
    Clin Pediatr (Phila) 2017 May;56(5_suppl):13S-15S
    1 Kenwood Dermatology, Cincinnati, OH, USA.
    Over the past several years, a number of articles and online posts have circulated on the Internet associating use of disposable and cloth diapers with chemical burns on babies' skin. Because both mild chemical burns and diaper dermatitis (diaper rash) can cause skin redness and peeling, it is not surprising that some confusion has arisen regarding the association between these two conditions. However, diapers cannot cause chemical burns because they are made of inert materials. Read More

    The Southwest UK Burns Network (SWUK) experience of electronic cigarette explosions and review of literature.
    Burns 2017 Jun 12;43(4):e1-e6. Epub 2017 Apr 12.
    Plastic and Reconstructive Surgery, Welsh Centre for Burns and Plastic Surgery (WCBP), Morriston Hospital, Swansea, SA6 6NL, UK. Electronic address:
    Introduction: Since the introduction of e-cigarettes to the UK market in 2007 their popularity amongst young adults has significantly increased. These lithium-ion powered devices remain unregulated by the Standards Agency and as a result burns centres across the world have seen an increasing number of patients presenting with significant burns, resulting from poor quality batteries that appear to be liable to explode when over-heated, over-charged or incorrectly stored.

    Methods: Retrospective and perspective review of all e-cigarette related burns presenting to the Southwest Burns Network; South Wales Burns Centre (Morriston Hospital) or to Bristol burns centre (Southmead Hospital) between Oct 15-July 16, followed by a review of available literature performed and eligible papers identified using PRISMA 2009 Checklist. Read More

    Measurement of the [Formula: see text] production cross section using events in the [Formula: see text] final state in pp collisions at [Formula: see text].
    Eur Phys J C Part Fields 2017 20;77(3):172. Epub 2017 Mar 20.
    University of Wisconsin-Madison, Madison, WI USA.
    The cross section of top quark-antiquark pair production in proton-proton collisions at [Formula: see text] is measured by the CMS experiment at the LHC, using data corresponding to an integrated luminosity of 2.2[Formula: see text]. The measurement is performed by analyzing events in which the final state includes one electron, one muon, and two or more jets, at least one of which is identified as originating from hadronization of a b quark. Read More