94,960 results match your criteria Burns : journal of the International Society for Burn Injuries[Journal]


Electrical stimulation facilitates the angiogenesis of human umbilical vein endothelial cells through MAPK/ERK signaling pathway by stimulating FGF2 secretion.

Am J Physiol Cell Physiol 2019 Apr 17. Epub 2019 Apr 17.

Department of Burns and Plastic Surgery, the Affiliated Hospital of Southwest Medical University, Luzhou 646000, China.

Electrical stimulation (ES) is able to enhance angiogenesis by stimulating fibroblasts. Fibroblast growth factor 2 (FGF2) is an independent angiogenesis inducer. The current study aimed to evaluate the role of ES-induced FGF2 secretion in affecting angiogenesis during wound healing the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway. Read More

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http://dx.doi.org/10.1152/ajpcell.00474.2018DOI Listing

Response to: Comparison of keystone flaps and skin grafts for oncologic reconstruction: A retrospective review.

J Surg Oncol 2019 Apr 17. Epub 2019 Apr 17.

Reconstructive Surgery & Regenerative Medicine Research Group (ReconRegen), Institute of Life Science 2, Swansea University Medical School, Swansea, UK.

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http://dx.doi.org/10.1002/jso.25478DOI Listing

The role of computer-assisted structure elucidation (CASE) programs in the structure elucidation of complex natural products.

Nat Prod Rep 2019 Apr 17. Epub 2019 Apr 17.

Department of Chemistry, University of Toronto, Toronto, Ontario, Canada.

Covering: up to the end of December, 2018There are still a disturbing number of incorrect natural product structure elucidations reported in the literature. The use of Computer-Assisted Structure Elucidation (CASE) programs can minimize this risk by generating all structures that are consistent with the input data and by ranking these structures in order of probability. They can successfully determine structures for complex natural products, with the possible exception of compounds with very few protons. Read More

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http://dx.doi.org/10.1039/c9np00007kDOI Listing

Irisin ameliorates septic cardiomyopathy via inhibiting DRP1-related mitochondrial fission and normalizing the JNK-LATS2 signaling pathway.

Cell Stress Chaperones 2019 Apr 16. Epub 2019 Apr 16.

Department of Emergency Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.

Irisin plays a protective effect in acute and chronic myocardial damage, but its role in septic cardiomyopathy is unclear. The aim of our study was to explore the in vivo and in vitro effects of irisin using an LPS-induced septic cardiomyopathy model. Our results demonstrated that irisin treatment attenuated LPS-mediated cardiomyocyte death and myocardial dysfunction. Read More

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http://dx.doi.org/10.1007/s12192-019-00992-2DOI Listing

When high viscosity of pancreatic cysts precludes effective EUS-FNA: a benchtop comparison of negative pressure devices.

Endosc Int Open 2019 Apr 12;7(4):E594-E599. Epub 2019 Apr 12.

Penn State Health Milton S. Hershey Medical Center, Division of Gastroenterology and Hepatology, Hershey, Pennsylvania, United States.

 Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) of pancreatic cystic lesions (PCLs) is an important diagnostic tool; however, it is often unsuccessful due to high viscosity of cystic fluid. In an effort to improve FNA, we objectively compared eight vacuum device configurations to determine the most effective method for aspirating viscous fluid collections. We also tested a high-frequency oscillation (HFO) technique that could be employed in FNA. Read More

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http://dx.doi.org/10.1055/a-0842-6332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461552PMC

Advances in surgical applications of growth factors for wound healing.

Burns Trauma 2019 5;7:10. Epub 2019 Apr 5.

Division of Plastic and Reconstructive Surgery, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, Shimane 693-8501 Japan.

Growth factors have recently gained clinical importance for wound management. Application of recombinant growth factors has been shown to mimic cell migration, proliferation, and differentiation , allowing for external modulation of the healing process. Perioperative drug delivery systems can enhance the biological activity of these growth factors, which have a very short half-life after topical administration. Read More

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http://dx.doi.org/10.1186/s41038-019-0148-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450003PMC

A novel minimal fluid technique for effective and safe lens hydrodissection during cataract surgery.

Taiwan J Ophthalmol 2019 Jan-Mar;9(1):43-45

Universal Eye Center, Taipei, Taiwan.

Traditional hydrodissection may cause posterior capsule rupture (PCR) if excessive fluid accumulates. In this study, we describe the successful application of a novel minimal fluid hydrodissection technique in 100 consecutive cataract surgery cases. This technique separates the nucleus from the capsule utilizing low hydrostatic pressure and precise kinetic movement of a small volume (around 0. Read More

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http://dx.doi.org/10.4103/tjo.tjo_137_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432847PMC

Utilizing intraoperative aberrometry and digital eye tracking to develop a novel nomogram for manual astigmatic keratotomy to effectively decrease mild astigmatism during cataract surgery.

Taiwan J Ophthalmol 2019 Jan-Mar;9(1):27-32

Taipei Nobel Eye Clinic, Taipei, Taiwan.

Purpose: The purpose of the study is to develop a novel nomogram and validate with a retrospective comparative study for manual astigmatic keratotomy (MAK) with the assistance of intraoperative aberrometry (Optiwave Refractive Analysis [ORA]) and digital eye tracking (VERION) in mild astigmatic correction enhancement.

Setting: The study was conducted in Honolulu, Hawaii.

Design: This was a single-surgeon comparative study with retrospective data collection. Read More

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http://dx.doi.org/10.4103/tjo.tjo_6_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432848PMC

Intraocular lens correction of presbyopia.

Taiwan J Ophthalmol 2019 Jan-Mar;9(1):4-17

Clinical Professor, John A Burns School of Medicine, University of Hawaii, Hawaii, USA.

The continued development of intraocular lens (IOL) technology has led to a dramatic improvement in refractive outcomes. New and innovative ways of achieving the desired postoperative refractive goals continue to be developed. This article aims to review the currently available IOL modalities for correction of presbyopia at the time of cataract surgery, including reference to high-quality comparative studies, where available, and discussion of strengths as well as limitations of the currently available IOL technologies. Read More

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http://www.e-tjo.org/text.asp?2019/9/1/4/252231
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http://dx.doi.org/10.4103/tjo.tjo_136_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432854PMC
April 2019
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Refractive cataract surgery - what we were, what we are, and what we will be: A personal experience and perspective.

Authors:
Ming Chen

Taiwan J Ophthalmol 2019 Jan-Mar;9(1):1-3

Department of Surgery, Division of Ophthalmology, John A. Burns School of Medicine, University of Hawai'i at Mānoa Honolulu, Hawai'i 96813, USA.

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http://dx.doi.org/10.4103/tjo.tjo_133_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432845PMC

The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory.

Nat Commun 2019 Apr 16;10(1):1766. Epub 2019 Apr 16.

Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Feodor-Lynen Straße 17, 81377, Munich, Germany.

The single nucleotide polymorphism (SNP) rs744373 in the bridging integrator-1 gene (BIN1) is a risk factor for Alzheimer's disease (AD). In the brain, BIN1 is involved in endocytosis and sustaining cytoskeleton integrity. Post-mortem and in vitro studies suggest that BIN1-associated AD risk is mediated by increased tau pathology but whether rs744373 is associated with increased tau pathology in vivo is unknown. Read More

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http://dx.doi.org/10.1038/s41467-019-09564-5DOI Listing

Transcriptional positive cofactor 4 promotes breast cancer proliferation and metastasis through c-Myc mediated Warburg effect.

Cell Commun Signal 2019 Apr 16;17(1):36. Epub 2019 Apr 16.

Institute of Rocket Force Medicine, State Key Laboratory of Trauma, Burns and Combined Injury, Third Military Medical University, Chongqing, 400038, China.

Background: The human positive cofactor 4 (PC4) is initially identified as a transcriptional cofactor and has an important role in embryonic development and malignant transformation. However, the clinical significance and the molecular mechanisms of PC4 in breast cancer development and progression are still unknown.

Methods: We investigated PC4 expression in 114 cases of primary breast cancer and matched normal breast tissue specimens, and studied the impact of PC4 expression as well as the molecular mechanisms of this altered expression on breast cancer growth and metastasis both in vitro and in vivo. Read More

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http://dx.doi.org/10.1186/s12964-019-0348-0DOI Listing

Clinical features and treatment of 140 cases of Marjolin's ulcer at a major burn center in southwest China.

Exp Ther Med 2019 May 7;17(5):3403-3410. Epub 2019 Mar 7.

State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, P.R. China.

Marjolin's ulcer is a type of malignant tumor that occurs in scar tissue. The present study aimed to summarize and analyze the aetiology, clinical characteristics, treatment methods, metastasis and prognosis of this disease. A total of 140 cases of Marjolin's ulcer encountered at the Institute of Burn Research, Southwest Hospital (Chongqing, China) between January 2013 and December 2017 were retrospectively analyzed. Read More

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http://dx.doi.org/10.3892/etm.2019.7364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447797PMC

Taking the path of least resistance: a qualitative analysis of return to work or study while breastfeeding.

Int Breastfeed J 2019 4;14:15. Epub 2019 Apr 4.

School of Nursing and Midwifery, Western Sydney University, Locked Bag 1797, Penrith, New South Wales Australia.

Background: In order to meet World Health Organization recommendations for breastfeeding, many women need to combine breastfeeding with return to work or study. Barriers are often encountered when returning to work or study, which can lead to premature cessation of breastfeeding. This study aimed to explore Australian women's experiences of breastfeeding at one multi-campus university. Read More

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http://dx.doi.org/10.1186/s13006-019-0209-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449947PMC

Physiological stress levels in wild koala sub-populations facing anthropogenic induced environmental trauma and disease.

Authors:
Edward Narayan

Sci Rep 2019 Apr 15;9(1):6031. Epub 2019 Apr 15.

School of Science and Health, Western Sydney University, Locked Bag 1797, Penrith, New South Wales, 2751, Australia.

Australian small mammals such as koalas must cope with immense pressure from anthropogenic induced stressors or trauma such as bushfires, vehicle collision impacts and habitat disturbance and land clearance. In addition, they must cope with diseases such as chlamydia. To date, there is no published literature on physiological stress levels in wild koala populations compared with identified environmental stressors. Read More

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http://dx.doi.org/10.1038/s41598-019-42448-8DOI Listing

Conflict across representational gaps: Threats to and opportunities for improved communication.

Proc Natl Acad Sci U S A 2019 Apr 15;116(16):7642-7649. Epub 2019 Apr 15.

Tepper School of Business, Carnegie Mellon University, Pittsburgh, PA 15213.

Often, the senders and receivers of scientific communication have different knowledge bases. While such communication is essential for solving the complex social and technological problems that affect multiple stakeholders, a diversity of knowledge among communicators can create representational gaps (rGaps). rGaps occur when senders make assumptions that receivers do not, creating conflict over the meaning and value of the information communicated. Read More

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http://dx.doi.org/10.1073/pnas.1805866116DOI Listing

Osmium-Labeled Microspheres for Bead-Based Assays in Mass Cytometry.

J Immunol 2019 Apr 15. Epub 2019 Apr 15.

German Rheumatism Research Centre Berlin, a Leibniz Institute, 10117 Berlin, Germany; and

Polystyrene beads are broadly applied in flow cytometry. Implementing bead-based assays in mass cytometry is desired but hampered by the lack of an elemental label required for their detection. In this study, we introduce stable osmium tetroxide labeling as a universal approach for generating functionalized beads readily detectable by mass cytometry. Read More

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http://dx.doi.org/10.4049/jimmunol.1801640DOI Listing

Non-Ionizing Radiation in Swedish Health Care-Exposure and Safety Aspects.

Int J Environ Res Public Health 2019 Apr 2;16(7). Epub 2019 Apr 2.

Department of Radiation Sciences, Umeå University, S-90185 Umeå, Sweden.

The main aim of the study was to identify and describe methods using non-ionizing radiation (NIR) such as electromagnetic fields (EMF) and optical radiation in Swedish health care. By examining anticipated exposure levels and by identifying possible health hazards we also aimed to recognize knowledge gaps in the field. NIR is mainly used in health care for diagnosis and therapy. Read More

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http://dx.doi.org/10.3390/ijerph16071186DOI Listing

Pediatric Emergency Medicine Simulation Curriculum: Hyponatremic Seizures.

MedEdPORTAL 2016 Nov 10;12:10498. Epub 2016 Nov 10.

Co-Director of Pediatric Emergency Medicine Simulation, Seattle Children's Hospital; Associate Professor of Emergency Medicine, University of Washington School of Medicine.

Introduction: Seizures are a common complaint in the pediatric emergency department. Effective care of this potentially life-threatening medical emergency requires the ability to stabilize the patient while simultaneously identifying and treating the underlying cause. This simulation-based curriculum involves the identification and management of a generalized seizure in a 4-month-old infant secondary to hyponatremia. Read More

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https://www.mededportal.org/publication/10498
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http://dx.doi.org/10.15766/mep_2374-8265.10498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440407PMC
November 2016
1 Read

Management of Major Burns in 37 Casualties of a Colored Powder Explosion: Experience of the Linkou Burn Center in Taiwan.

Ann Plast Surg 2019 May;82(5):512-519

From the Department of Plastic and Reconstructive Surgery, and.

Background: On June 27, 2015, a colored powder explosion occurred in Taiwan. As a result, 499 people were injured, and over 200 people were in critical condition because of severe burns. Forty-nine casualties were transported to the Chang Gung Memorial Hospital. Read More

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http://dx.doi.org/10.1097/SAP.0000000000001928DOI Listing
May 2019
1 Read

Lessons Learned From a Burn-Injured Pediatric Patient With Dandy-Walker Syndrome After Multiple Anesthetics: A Case Report.

A A Pract 2019 Apr 8. Epub 2019 Apr 8.

From the Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas.

Dandy-Walker syndrome is a rare congenital brain malformation that requires unique anesthetic considerations. We present a rare case of an 18-month-old boy with Dandy-Walker syndrome presenting with 17% total body surface area burns undergoing multiple general anesthetics or both operative and bedside procedures. Numerous lessons were learned during multiple anesthetics, which influenced and guided our subsequent anesthetic management. Read More

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http://dx.doi.org/10.1213/XAA.0000000000001014DOI Listing

Urinary mutagenicity and other biomarkers of occupational smoke exposure of wildland firefighters and oxidative stress.

Inhal Toxicol 2019 Apr 15:1-15. Epub 2019 Apr 15.

a Department of Environmental Health Sciences , College of Public Health, University of Georgia , Athens , GA , USA.

Background: Wildland firefighters conducting prescribed burns are exposed to a complex mixture of pollutants, requiring an integrated measure of exposure.

Objective: We used urinary mutagenicity to assess if systemic exposure to mutagens is higher in firefighters after working at prescribed burns versus after non-burn work days. Other biomarkers of exposure and oxidative stress markers were also measured. Read More

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http://dx.doi.org/10.1080/08958378.2019.1600079DOI Listing

Are Sluggish Cognitive Tempo, ADHD, and Oppositional Defiant Disorder Trait- or State-Like Constructs from Prekindergarten to Fourth Grade?

J Clin Child Adolesc Psychol 2019 Apr 15:1-9. Epub 2019 Apr 15.

d Department of Psychology and Neuroscience , University of Colorado Boulder.

The objective was to determine the proportion of trait (consistency across occasions) and occasion-specific variance in sluggish cognitive tempo (SCT), attention deficit/hyperactivity disorder (ADHD)-inattention (IN), ADHD-hyperactivity/impulsivity (HI), and oppositional defiant disorder (ODD) symptom ratings. A single trait factor-multiple state factors model was applied to parent ratings of SCT, ADHD-IN, ADHD-HI, and ODD symptoms for 978 children (50% female) across prekindergarten (M= 4.90 years), kindergarten (M = 6. Read More

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http://dx.doi.org/10.1080/15374416.2019.1567348DOI Listing

Using Bioactive Glasses in the Management of Burns.

Front Bioeng Biotechnol 2019 28;7:62. Epub 2019 Mar 28.

Applied Science and Technology Department, Institute of Materials Physics and Engineering, Politecnico di Torino, Turin, Italy.

The management of burn injuries is considered an unmet clinical need and, to date, no fully satisfactory solution exists to this problem. This mini-review aims to explore the potential of bioactive glasses (BGs) for burn care due to the therapeutic effects of their ionic dissolution products. BGs have been studied for more than 40 years and boast a long successful history in the substitution of damaged tissues, especially bone. Read More

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http://dx.doi.org/10.3389/fbioe.2019.00062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447657PMC
March 2019
1 Read

Knowledge and practices related to burn first aid among Majmaah community, Saudi Arabia.

J Family Med Prim Care 2019 Feb;8(2):594-598

Associate Professor, Department of Community Medicine and Epidemiology, College of Medicine, Majmaah University, Al Majma'ah, Kingdom of Saudi Arabia.

Background: Burns in developing countries account for significant morbidity and mortality which have been shown by increasing burn first aid awareness. In general, flames, scalds, and contact burns are the most common causes, but in children scalds are the most common.

Objectives: This study aims to assess the general knowledge and practices related to burn first aid among Majmaah community. Read More

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http://dx.doi.org/10.4103/jfmpc.jfmpc_382_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436272PMC
February 2019

Awareness of Cosmetic Dermatology Procedures among Health Workers in a Tertiary Care Hospital.

Authors:
Deeptara P Thapa

Indian Dermatol Online J 2019 Mar-Apr;10(2):139-143

Department of Dermatology, Nepal Medical College and Teaching Hospital, Gokarneshwar, Kathmandu, Nepal.

Introduction: Cosmetic dermatology is a branch of dermatology which deals with the enhancement of beauty. There is a rise in cosmetic dermatological procedures throughout the world, but its awareness is limited not only in the general population but also among the health workers.

Materials And Methods: We conducted a cross-sectional questionnaire-based study to know the knowledge and awareness of cosmetic dermatological procedures among health workers in a hospital setting. Read More

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http://dx.doi.org/10.4103/idoj.IDOJ_70_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434758PMC
April 2019
1 Read

International Abstracts.

Authors:

Ann Burns Fire Disasters 2018 Dec;31(4):338-339

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441577PMC
December 2018

Report.

Authors:

Ann Burns Fire Disasters 2018 Dec;31(4):336-337

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441575PMC
December 2018

MBC News.

Authors:

Ann Burns Fire Disasters 2018 Dec;31(4):335

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441580PMC
December 2018

Comparative plasma phenylalanine and glutamate profiles in scalded rats treated with Mebo or Copper (I) Nicotinate Complex.

Ann Burns Fire Disasters 2018 Dec;31(4):329-334

Assiut University, Assiut, Egypt.

The time profile of total proteins and albumin in line with two amino acids, Phe and Glu, are of great importance due to their indicative value of the healing and/or deterioration of burn wounds. In this experiment, rats exposed to scalding that produced a second-degree burn were divided into four groups: control, placebo, MEBO ointment, and copper (I) nicotinate complex ointment (an antioxidant anti-inflammatory) for four weeks. The three treatments showed noticeable similarities in the Phe profiles, with a slight drop 24 hours post burn, a peak elevation by the second week, and a slight, insignificant decline by the third week, with the placebo group showing highest values over normal (P< 0. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441581PMC
December 2018

Preparation for major burns incidents: evaluation of continuing medical education training courses for professionals.

Ann Burns Fire Disasters 2018 Dec;31(4):322-328

National Institute of Burns, Hanoi, Vietnam.

The purpose of this study was to identify changes in the competence of healthcare providers who underwent training courses on the management of burns incidents. Theoretical and practical simulation training courses were conducted for 305 healthcare providers from emergency and trauma departments of general hospitals in Vietnam. Pre- and post-tests were conducted using questionnaires and with simulated practical skill evaluation by burns specialists. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441574PMC
December 2018
5 Reads

Cardiovascular risk in fire academy instructors during live-fire simulation activity.

Ann Burns Fire Disasters 2018 Dec;31(4):313-321

Gyeonggi-do Fire Service Academy, South Korea.

Firefighting is an extreme occupation with a risk of cardiovascular disease and sudden cardiac death due to strenuous physical exertion and psychological stress during fire suppression activity. This study aimed to investigate the vital signs (hemodynamic status) and biomarkers related to cardiac disease during live firefighting activity. In this pilot case-controlled study, seven firefighting training instructors performed a live-fire simulation for 40 min in a multi-storey training tower at the Gyenoggi-do Fire Service Academy Institute. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441576PMC
December 2018

The square flap technique for burn contractures: clinical experience and analysis of length gain.

Authors:
M A Hifny

Ann Burns Fire Disasters 2018 Dec;31(4):306-312

Department of Plastic Surgery, Faculty of Medicine, Qena University Hospital, South Valley University, Egypt.

Post-burn contractures, affecting the joints especially, are demanding problems. Many surgical techniques have been designated for burn contracture release. The aim of this study is to investigate the efficiency of the square flap technique to release a post-burn scar contracture, and assess the post-operative length gain that can be achieved by simple mathematical calculation. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441585PMC
December 2018
1 Read

The effects of Platelet-rich Plasma on healing of partial thickness burns in a porcine model.

Ann Burns Fire Disasters 2018 Dec;31(4):298-305

Department of Emergency Medicine, Stony Brook University, Stony Brook, NY, USA.

Platelet-rich plasma (PRP) derived from autologous peripheral blood is rich in platelets that release growth factors and cytokines. We determined the effects of topically applied autologous PRP in a partial thickness porcine burn model. Partial thickness burns were created on the backs and flanks of six domestic pigs (24 burns each) using an aluminium bar preheated to 80° C for 20 seconds. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441582PMC
December 2018

Auto-transplantation of amnion-chorion membrane in a burned pregnant patient at term.

Ann Burns Fire Disasters 2018 Dec;31(4):292-297

University Hassan II, Casablanca, Morocco.

Burn in pregnancy represents a threat to the mother and the fetus. Burn care in pregnant women is not well codified. An aggressive treatment including oxygen supplementation, smart fluid resuscitation and early excision has been reported. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441572PMC
December 2018

Effect of denervation on burn wound healing.

Ann Burns Fire Disasters 2018 Dec;31(4):278-291

Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

The skin is a natural barrier between the interior milieu of the organism and its environment. This barrier has multiple physiological functions and may be affected by an array of pathologies including wounds and burns. The present study aims to determine the effect of the nervous system on wound healing. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441573PMC
December 2018

Risk factors and outcome of Hypernatremia amongst severe adult burn patients.

Authors:
N N Lam N T N Minh

Ann Burns Fire Disasters 2018 Dec;31(4):271-277

Vietnam National Institute of Burns, Hanoi, Vietnam.

A descriptive study was conducted on 135 adult severe burn patients treated at the Burn ICU, National Institute of Burns from 1/2017 to 12/2017. Hypernatremia was defined as increased plasma sodium ≥ 146 mmol/l. It was recorded in 24. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441579PMC
December 2018
1 Read

Toxic epidermal necrolysis after acute burn injury.

Ann Burns Fire Disasters 2018 Dec;31(4):266-270

National Burns Unit, Saint James' Hospital, Dublin, Republic of Ireland.

Toxic epidermal necrolysis is a rare, potentially fatal disorder that involves large areas of skin desquamation. Patients with toxic epidermal necrolysis are frequently referred to burn centres for expert wound management and early comprehensive critical care as this has been shown to improve patient outcome and mortality. The authors describe the first report of medication-induced toxic epidermal necrolysis occurring in a patient during acute burn management in a tertiary burn care facility. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441584PMC
December 2018

Twelve years of Lyell's Syndrome in the burn unit of São João Hospital Centre.

Ann Burns Fire Disasters 2018 Dec;31(4):259-265

Plastic Surgery and Burns Unit, Centro Hospitalar São João, Porto, Portugal.

Stevens-Johnson syndrome (SSJ) and toxic epidermal necrolysis (TEN) correspond to an acute and rare life-threatening mucocutaneous reaction. We describe the etiology, length of stay, comorbidities and mortality of TEN in our hospital in a retrospective study of 12 years. Twenty-one patients were included in the study. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441583PMC
December 2018

Serial abdominal closure with Gore-tex mesh and Rives-Stoppa for an open abdomen secondary to intra-abdominal hypertension in burns.

Indian J Plast Surg 2018 Sep-Dec;51(3):324-326

St Andrew's Centre for Burns and Plastic Surgery, Broomfield Hospital, Chelmsford, Essex, CM1 7ET, UK.

Intra-abdominal hypertension (IAH) leading to abdominal compartment syndrome (ACS) commonly occurs in major burns. To relieve the excess pressure, decompressive laparotomy is done which can lead to an open abdomen. Closure of the abdomen after a decompressive laparotomy is very difficult with bowel oedema. Read More

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http://dx.doi.org/10.4103/ijps.IJPS_75_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440362PMC

Marking of temporal point and lower border of temporal triangle in planning hair transplantation for male-pattern baldness.

Indian J Plast Surg 2018 Sep-Dec;51(3):316-320

Department of Burns and Plastic Surgery, B.J. Medical College, Gujarat University, Ahmedabad, Gujarat, India.

Introduction: Temporal recession in male-pattern baldness is common. The method of marking of temporal point practiced worldwide, described by Walter P. Unger, does not help in marking temporal triangle border in Indian population. Read More

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http://dx.doi.org/10.4103/ijps.IJPS_135_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440355PMC

Intraoperative partial pressure of oxygen measurement to predict flap survival.

Indian J Plast Surg 2018 Sep-Dec;51(3):266-273

Department of Burns, Plastic and Maxillofacial Surgery, Dr. Ram Manohar Lohia Hospital and Post Graduate Institute of Medical Education and Research, New Delhi, India.

Introduction: Flap monitoring using partial pressure of oxygen (pO) is a proven modality. Instruments needed are expensive and are not readily available to a clinician. Here, pO of flap has been determined using readily available and cheap methods, and a cut-off value is calculated which helps in predicting flap outcome. Read More

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http://dx.doi.org/10.4103/ijps.IJPS_35_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440342PMC

Socioeconomic and Demographic Factors Influencing Women's Attitude Toward Wife Beating in Ethiopia.

Authors:
Alemu A Mengistu

J Interpers Violence 2019 Apr 15:886260519842179. Epub 2019 Apr 15.

1 SolBridge International School of Business, Daejeon, Republic of Korea.

This study used data from the Ethiopian Demographic and Health Survey (EDHS) for a total of 42,054 women (15-49 years) from Ethiopia's 11 geographic/administrative regions using a stratified, two-stage cluster sample design to reflect the country's huge geographical, cultural, ethnic, and linguistic diversity. The study first identified the major socioeconomic and demographic factors influencing women's attitude toward wife beating in Ethiopia, and then provided some suggestions on what types of interventions are required to address the problems. Toward this effect, female participants were asked whether a husband is justified in beating his wife under five possible circumstances. Read More

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http://dx.doi.org/10.1177/0886260519842179DOI Listing
April 2019
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A novel cross-linked haemoglobin-based oxygen carrier is beneficial to sepsis in rats.

Artif Cells Nanomed Biotechnol 2019 Dec;47(1):1496-1504

a State Key Laboratory of Trauma, Burns and Combined Injury, Second Department of Research Institute of Surgery, Daping Hospital , Third Military Medical University (Army Medical University) , Chongqing , P.R. China.

Pathological hypoxia-induced organ dysfunction contributes to the high mortality of sepsis. Because of the microcirculation dysfunction following severe sepsis, it is difficult for erythrocytes to transport oxygen to hypoxic tissues. Haemoglobin-based oxygen carriers (HBOCs) are capable of delivering oxygen to hypoxic tissues. Read More

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http://dx.doi.org/10.1080/21691401.2019.1602049DOI Listing
December 2019

The Effect of Enzymatic Digestion on Cultured Epithelial Autografts.

Cell Transplant 2019 Apr 15:963689719833305. Epub 2019 Apr 15.

2 Department of Hand Surgery, Plastic Surgery and Burns, and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

Severe burns are often treated by means of autologous skin grafts, preferably following early excision of the burnt tissue. In the case of, for example, a large surface trauma, autologous skin cells can be expanded in vitro prior to transplantation to facilitate the treatment when insufficient uninjured skin is a limitation. In this study we have analyzed the impact of the enzyme (trypsin or accutase) used for cell dissociation and the incubation time on cell viability and expansion potential, as well as expression of cell surface markers indicative of stemness. Read More

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http://dx.doi.org/10.1177/0963689719833305DOI Listing

Integrated Transcriptomic and Proteomic Analysis of Primary Human Umbilical Vein Endothelial cells.

Proteomics 2019 Apr 14:e1800315. Epub 2019 Apr 14.

A. K. Madugundu, A. Pandey, Center for Molecular Medicine, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore, 560029, India.

Understanding the molecular profile of every human cell type is essential for understanding its role in normal physiology and disease. Technological advancements in DNA sequencing, mass spectrometry and computational methods allow us to carry out multi-Omics analyses although such approaches are not routine yet. Human umbilical vein endothelial cells (HUVECs) are a widely-used model system to study pathological and physiological processes associated with the cardiovascular system. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/pmic.2018003
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http://dx.doi.org/10.1002/pmic.201800315DOI Listing
April 2019
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Key factors for sustainable integration of pharmacists in team-based primary care physician practices.

J Am Pharm Assoc (2003) 2019 Apr 11. Epub 2019 Apr 11.

Objectives: To (1) identify strategies for financial justification of pharmacists integrated into team-based primary care, (2) describe the payment models currently used for integration of pharmacists into team-based primary care, and (3) elicit key factors facilitating sustainable pharmacist-provided patient care services in the primary care setting.

Design: Qualitative analysis using semistructured interviews.

Setting: Nonacademic outpatient primary care physician practices throughout the United States from January to April 2014. Read More

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http://dx.doi.org/10.1016/j.japh.2019.02.005DOI Listing

Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia.

Am J Hum Genet 2019 Apr 10. Epub 2019 Apr 10.

Molecular Neurosciences, Developmental Neurosciences, UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK; Department of Neurology, Great Ormond Street Hospital, London WC1N 3JH, UK. Electronic address:

The occurrence of non-epileptic hyperkinetic movements in the context of developmental epileptic encephalopathies is an increasingly recognized phenomenon. Identification of causative mutations provides an important insight into common pathogenic mechanisms that cause both seizures and abnormal motor control. We report bi-allelic loss-of-function CACNA1B variants in six children from three unrelated families whose affected members present with a complex and progressive neurological syndrome. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029297193010
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http://dx.doi.org/10.1016/j.ajhg.2019.03.005DOI Listing
April 2019
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Plasma for burn shock resuscitation: is it time to go back to the future?

Transfusion 2019 Apr;59(S2):1578-1586

US Army Institute of Surgical Research, San Antonio, Texas.

Patients with burn shock can be challenging to resuscitate. Burn shock produces a variety of physiologic derangements: Patients are hypovolemic from volume loss, have a increased systemic vascular resistance, and may have a depressed cardiac output depending on the extent of the thermal injury. Additionally, the burn wound produces a significant inflammatory cascade of events that contributes to the shock state. Read More

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http://dx.doi.org/10.1111/trf.15243DOI Listing

Potential Airborne Asbestos Exposure and Risk Associated with the Historical Use of Cosmetic Talcum Powder Products.

Risk Anal 2019 Apr 12. Epub 2019 Apr 12.

Insight Risk, LLC, Boulder, CO, USA.

Over time, concerns have been raised regarding the potential for human exposure and risk from asbestos in cosmetic-talc-containing consumer products. In 1985, the U.S. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/risa.13312
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http://dx.doi.org/10.1111/risa.13312DOI Listing
April 2019
4 Reads