4,751 results match your criteria Burn Rehabilitation


Management of Major Burns in 37 Casualties of a Colored Powder Explosion: Experience of the Linkou Burn Center in Taiwan.

Ann Plast Surg 2019 May;82(5):512-519

From the Department of Plastic and Reconstructive Surgery, and.

Background: On June 27, 2015, a colored powder explosion occurred in Taiwan. As a result, 499 people were injured, and over 200 people were in critical condition because of severe burns. Forty-nine casualties were transported to the Chang Gung Memorial Hospital. Read More

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http://dx.doi.org/10.1097/SAP.0000000000001928DOI Listing
May 2019
2 Reads

Toxic epidermal necrolysis after acute burn injury.

Ann Burns Fire Disasters 2018 Dec;31(4):266-270

National Burns Unit, Saint James' Hospital, Dublin, Republic of Ireland.

Toxic epidermal necrolysis is a rare, potentially fatal disorder that involves large areas of skin desquamation. Patients with toxic epidermal necrolysis are frequently referred to burn centres for expert wound management and early comprehensive critical care as this has been shown to improve patient outcome and mortality. The authors describe the first report of medication-induced toxic epidermal necrolysis occurring in a patient during acute burn management in a tertiary burn care facility. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441584PMC
December 2018
2 Reads

Negative pressure wound therapy versus microcurrent electrical stimulation in wound healing in burns.

J Wound Care 2019 Apr;28(4):214-219

Assistant Professor, Department of Basic Science for Physical Therapy, Faculty of Physical Therapy, Cairo University, Egypt.

Objective: To compare the efficacy of negative pressure wound therapy (NPWT) with that of microcurrent electrical stimulation (MES) on wound surface area, length of stay (LoS) and colony count of wounds in patients with burns.

Method: Patients with thermal dermal burn injuries covering 25-40% of total body surface area were enrolled in this clinical trial. Participants were randomly allocated into three, equal-sized groups: patients receiving NPWT, patients receiving MES and a control group which received standard wound care. Read More

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http://dx.doi.org/10.12968/jowc.2019.28.4.214DOI Listing
April 2019
1 Read

Multicentre pilot randomised clinical trial of early in-bed cycle ergometry with ventilated patients.

BMJ Open Respir Res 2019 18;6(1):e000383. Epub 2019 Feb 18.

Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.

Introduction: Acute rehabilitation in critically ill patients can improve post-intensive care unit (post-ICU) physical function. In-bed cycling early in a patient's ICU stay is a promising intervention. The objective of this study was to determine the feasibility of recruitment, intervention delivery and retention in a multi centre randomised clinical trial (RCT) of early in-bed cycling with mechanically ventilated (MV) patients. Read More

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http://dx.doi.org/10.1136/bmjresp-2018-000383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424272PMC
February 2019
2 Reads

Racial disparities in post-discharge healthcare utilization after trauma.

Am J Surg 2019 Apr 1. Epub 2019 Apr 1.

Department of Surgery, Division of Trauma, Burn and Surgical Critical Care, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

Background: Racial disparities in trauma outcomes have been documented, but little is known about racial differences in post-discharge healthcare utilization. This study compares the utilization of post-discharge healthcare services by African-American and Caucasian trauma patients.

Methods: Trauma patients with an Injury Severity Score (ISS)≥9 from three Level-I trauma centers were contacted between 6 and 12 months post-injury. Read More

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http://dx.doi.org/10.1016/j.amjsurg.2019.03.024DOI Listing

Balloon Catheter Dilatation for Treatment of a Patient with Cricopharyngeal Dysfunction After Thermal Burn Injury.

J Burn Care Res 2019 Apr 6. Epub 2019 Apr 6.

Department of Rehabilitation Medicine, Hangang Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Korea.

Deglutition disorder is a clinical symptom that has been associated with inhalation and cutaneous thermal burn injuries. Deglutition disorder is present in approximately 11% of patients with burn injury and is known to persist for weeks to months postinjury. Here, we report a case of deglutition disorder associated with cricopharyngeal dysfunction(CPD) in a patient with thermal burn injury. Read More

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http://dx.doi.org/10.1093/jbcr/irz044DOI Listing
April 2019
1 Read

The prevalence and development of burn scar contractures: A prospective multicenter cohort study.

Burns 2019 Apr 1. Epub 2019 Apr 1.

Burn Centre, Dept of Plastic and Reconstructive Surgery, Red Cross Hospital, Beverwijk, The Netherlands; Department of Plastic, Reconstructive and Hand Surgery, Amsterdam Movement Sciences VU University Medical Centre, Amsterdam, The Netherlands.

Objective: The objective of this study was to identify the prevalence and development of after burn joint limitation by scar contracture.

Methods: In 2011-2012, consecutive patients were enrolled in this prospective multi center cohort study. Eligible were all patients admitted to the 2 participating Dutch Burn Centers with acute burns across or adjacent to the neck, shoulder, elbow, wrist, hip, knee and ankle. Read More

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http://dx.doi.org/10.1016/j.burns.2019.03.007DOI Listing
April 2019
1 Read

[Randomized controlled trial of internal heat-type acupuncture needle therapy in the treatment of post-stroke shoulder pain].

Zhen Ci Yan Jiu 2019 Mar;44(3):205-10

Rehabilitation Department, Tongren Hospital of Wuhan University, Wuhan Third Hospital, Wuhan 430060, China.

Objective: To evaluate the effectiveness and safety of internal heat-type acupuncture needle (IHTAN) the-rapy in the treatment of post-stroke shoulder pain in apopletic patients.

Methods: According to the random number table, 96 patients with post-stroke shoulder pain were divided into IHTAN group and warm needle moxibustion group (=48 in each one). Jianyu (LI15), Jianliao (TE14), Jianzhen (SI9), Binao (LI14) and Ashi points (Extra) on the affected side were selected in the two groups. Read More

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http://dx.doi.org/10.13702/j.1000-0607.170743DOI Listing
March 2019
1 Read

What Happens after a Positive Screen for Depression and Post Traumatic Stress Disorder in the Outpatient Burn Clinic?

J Burn Care Res 2019 Apr 3. Epub 2019 Apr 3.

UC Irvine Department of Surgery.

Multiple reports have demonstrated a wide prevalence of both depression and post-traumatic stress disorder (PTSD) within one year of burn injury. The purpose of this study is to determine outcomes of burn patients after a positive outpatient screen for depression or PTSD at an American Burn Association (ABA)-verified burn center. All patients who screened positive were offered referral for psychologic and/or psychiatric counseling. Read More

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http://dx.doi.org/10.1093/jbcr/irz051DOI Listing
April 2019
1 Read

Frequency of Screening for Weaning From Mechanical Ventilation: Two Contemporaneous Proof-of-Principle Randomized Controlled Trials.

Crit Care Med 2019 Mar 27. Epub 2019 Mar 27.

Division of Critical Care, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada.

Objectives: It is unknown whether more frequent screening of invasively ventilated patients, identifies patients earlier for a spontaneous breathing trial, and shortens the duration of ventilation. We assessed the feasibility of conducting a large trial to evaluate screening frequency in critically ill adults in the North American context.

Design: We conducted two contemporaneous, multicenter, pilot, randomized controlled trials (the LibeRation from MEchanicaL VEntilAtion and ScrEening Frequency [RELEASE] and Screening Elderly PatieNts For InclusiOn in a Weaning [SENIOR] trials) to address concerns regarding the potential for higher enrollment, fewer adverse events, and better outcomes in younger patients. Read More

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http://dx.doi.org/10.1097/CCM.0000000000003722DOI Listing
March 2019
1 Read

Goniometric measurement of burn scar contracture: a paradigm shift challenging the standard. AUTHORS.

J Burn Care Res 2019 Mar 28. Epub 2019 Mar 28.

University of California, Davis, Sacramento, CA.

Standard goniometry is the most commonly used method of assessing range of motion (ROM) in patients with burn scar contracture. However, standard goniometry was founded on arthrokinematic principles and doesn't consider the cutaneous biomechanical influence between adjacent joint positions and skin pliability to accommodate motion. Therefore, use of standard goniometry to measure burn scar contracture is called into question. Read More

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https://academic.oup.com/jbcr/advance-article/doi/10.1093/jb
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http://dx.doi.org/10.1093/jbcr/irz038DOI Listing
March 2019
5 Reads

Patterns of Medical Cannabis Use among Cancer Patients from a Medical Cannabis Dispensary in New York State.

J Palliat Med 2019 Mar 25. Epub 2019 Mar 25.

1 Department of Medicine, New York University School of Medicine, New York, New York.

Background: Research on the patterns of use of medical cannabis among cancer patients is lacking.

Objective: To describe patterns of medical cannabis use by patients with cancer, and how patterns differ from patients without cancer.

Design/measurements: We performed secondary data analysis using data from a medical cannabis licensee in New York State, analyzing demographic information, qualifying conditions, and symptoms, and the medical cannabis product used, including tetrahydrocannabinol (THC) to cannabidiol (CBD) ratios. Read More

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http://dx.doi.org/10.1089/jpm.2018.0529DOI Listing
March 2019
1 Read

Cardiovascular health and dementia incidence among older adults in Latin America: results from the 10/66 Study.

Int J Geriatr Psychiatry 2019 Mar 25. Epub 2019 Mar 25.

McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.

Objectives: Growing evidence shows that cardiovascular health (CVH) is associated with brain health. Little is known about this topic among older adults in Latin America, where the number of people living with dementia is rising. This study aimed to assess the longitudinal association between cardiovascular health and dementia in six Latin American countries. Read More

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http://dx.doi.org/10.1002/gps.5107DOI Listing
March 2019
2.866 Impact Factor

Carbon debris and fiber cleaving: Effects on potassium-titanyl-phosphate laser energy and chorioallantoic membrane model vessel coagulation.

Laryngoscope 2019 Mar 25. Epub 2019 Mar 25.

Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts, U.S.A.

Objectives/hypothesis: Photoangiolytic precision afforded by the 532-nm potassium-titanyl-phosphate (KTP) laser relies on predictable energy delivery. Inadequate energy output can cause vessel rupture, and excessive energy can cause thermal damage. The quality of the cleaved surface and carbon deposits from ablated tissue are two factors that could negatively impact fiber performance. Read More

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http://dx.doi.org/10.1002/lary.27948DOI Listing
March 2019
1 Read

Respiratory Management in Smoke Inhalation Injury.

J Burn Care Res 2019 Mar 20. Epub 2019 Mar 20.

Department of Respiratory Therapy, Fu Jen Catholic University Hospital, Fu Jen Catholic University, New Taipei City, Taiwan.

Smoke inhalation injury is a major morbidity and cause of mortality in patients with burns. Damage caused by inhalation of thermal or chemical irritants, including toxic fumes and chemicals, leads to respiratory cilia and epithelial cell injuries, which turn to severe bronchospasm and alveolar damage and results in acute respiratory distress syndrome. Respiratory management plays a vital role in the treatment of smoke inhalation injury. Read More

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http://dx.doi.org/10.1093/jbcr/irz043DOI Listing
March 2019
1 Read

A Theoretical Model of Spousal Caregiving Postintensive Care.

Authors:
Margie E Burns

Nurs Sci Q 2019 Apr;32(2):120-126

1 Clinical Nurse Educator, Intensive Care Unit, Queen Elizabeth Hospital, Charlottetown, Prince Edward Island, Canada.

Assuming the role of caregiver for a life partner after critical illness can be both a rewarding and challenging experience for spouses. Using a grounded theory approach, Ågård, Egerod, Tønnesen, and Lomborg developed a theoretical model describing the experience from spouse to caregiver and back. To further develop this theoretical model, a literature review was completed and nursing interventions were identified and included in the model. Read More

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http://dx.doi.org/10.1177/0894318419826230DOI Listing

Goal-oriented cognitive rehabilitation for early-stage Alzheimer's and related dementias: the GREAT RCT.

Health Technol Assess 2019 Mar;23(10):1-242

Dementia Services Development Centre, Bangor University, Bangor, UK.

Background: Cognitive rehabilitation (CR) is an individualised, person-centred intervention for people with mild to moderate dementia that addresses the impact of cognitive impairment on everyday functioning.

Objectives: To determine whether or not CR is a clinically effective and cost-effective intervention for people with mild to moderate Alzheimer's disease or vascular or mixed dementia, and their carers.

Design: This multicentre randomised controlled trial compared CR with treatment as usual (TAU). Read More

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http://dx.doi.org/10.3310/hta23100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441850PMC
March 2019
1 Read

Effects of early versus delayed excision and grafting on restoring the functionality of deep burn injured hands: A double blind, randomized parallel clinical trial.

J Burn Care Res 2019 Mar 15. Epub 2019 Mar 15.

Physiotherapy and Rehabilitation BSc, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Hand burns have major impacts on daily activities. An interdisciplinary and multifaceted approach is necessary to effectively treat these burns. Generally, hands are common sites for burn injuries. Read More

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http://dx.doi.org/10.1093/jbcr/irz033DOI Listing

[Severe burned patient rehabilitation].

Rev Prat 2018 Dec;68(10):1092-1095

Centre de rééducation de Coubert, Coubert, France.

Severe burned patient rehabilitation. The rehabilitation of the severe burn requires multidisciplinary care in a specialized rehabilitation center. We present in this article, the care offered in our service, detailing in particular the psychological aspects. Read More

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December 2018

Gain fonctionnel, antalgique et esthétique de la lipostructure dans les séquelles de brûlures.

Ann Burns Fire Disasters 2018 Sep;31(3):238-242

Centre Hospitalier Saint Joseph Saint Luc, Lyon, France.

The use of lipostructure to treat burn sequelae is more and more common today. The regeneration capacities of mesenchymal stem cells appear promising on this sequelae skin, which is poorly vascularized, retractile and often painful. The aim of our study is to establish the analgesic properties, and the functional and aesthetic improvements gained by using lipostructure to treat burn sequelae. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367862PMC
September 2018
4 Reads

Aging and burn: a five-year retrospective study in a major burn centre in Portugal.

Ann Burns Fire Disasters 2018 Sep;31(3):163-167

Department of Plastic Surgery and Burns Unit, Centro Hospitalar e Universitário de Coimbra (CHUC), Coimbra, Portugal.

Aging is an important factor contributing decisively to the clinical outcome of burn patients. The aim of this study was to assess the characteristics of patients admitted to a Burn Unit and determine the impact of aging on mortality. A retrospective analysis of patients successively admitted to a major burn centre in Portugal from 1/1/2012 to 31/12/2016 was conducted. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367867PMC
September 2018
1 Read

Clinical effects of transparent facial pressure masks: A literature review.

Prosthet Orthot Int 2019 Mar 12:309364619836023. Epub 2019 Mar 12.

1 Department of Plastic, Reconstructive, and Hand Surgery, Maastricht University Medical Center, The Netherlands.

Background:: Severe facial hypertrophic scars are known to severely impact emotional well-being. Pressure therapy by means of transparent face masks has been used for almost 40 years, but evidence about the clinical effects remains sparse.

Objectives:: To provide a summary on the efficacy of transparent face masks in the treatment of facial hypertrophic scars. Read More

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http://dx.doi.org/10.1177/0309364619836023DOI Listing
March 2019
4 Reads

A Review of Perforator Flaps for Burn Scar Contractures of Joints.

Plast Surg (Oakv) 2019 Feb 19;27(1):66-77. Epub 2018 Apr 19.

Section of Plastic Surgery, University of Calgary, Calgary, Alberta, Canada.

Objective: Perforator flaps are one possible surgical treatment for burn scar contractures; however, a review of evidence on this topic is lacking.

Methods: MEDLINE was searched for articles related to perforator flaps for burn contractures. Following title and abstract screen, full texts were searched to identify articles describing perforator flaps for burn scar joint contractures. Read More

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http://dx.doi.org/10.1177/2292550318767433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399780PMC
February 2019

Burn survivors injured as children exhibit resilience in long-term community integration outcomes: A life impact burn recovery evaluation (LIBRE) study.

Burns 2019 Mar 5. Epub 2019 Mar 5.

Spaulding Rehabilitation Hospital, Harvard Medical School, United States; Massachusetts General Hospital, Shriners Hospitals for Children-Boston, Harvard Medical School, United States. Electronic address:

Introduction: There is limited understanding of how burn injuries at different ages are associated with normal growth and development as well as the burn recovery process. This study provides new useful insights by comparing social participation outcomes among burn survivors injured in childhood compared with injuries sustained in middle age, and older adulthood.

Methods: Items from the development of the LIBRE profile were administered to 601 adult burn survivors with ≥5% TBSA burned or burns to critical areas (hands, feet, face, or genitals). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03054179183048
Publisher Site
http://dx.doi.org/10.1016/j.burns.2019.02.008DOI Listing
March 2019
5 Reads

Effect of small-vessel disease on cognitive trajectory after atrial fibrillation-related ischaemic stroke or  TIA.

J Neurol 2019 May 7;266(5):1250-1259. Epub 2019 Mar 7.

Department of Brain Repair and Rehabilitation, Stroke Research Centre, UCL Queen Square Institute of Neurology and National Hospital for Neurology and Neurosurgery, Russell Square House, 10-12 Russell Square, London, WC1B 5EH, UK.

Post-stroke dementia is common but has heterogenous mechanisms that are not fully understood, particularly in patients with atrial fibrillation (AF)-related ischaemic stroke or TIA. We investigated the relationship between MRI small-vessel disease markers (including a composite cerebral amyloid angiopathy, CAA, score) and cognitive trajectory over 12 months. We included patients from the CROMIS-2 AF study without pre-existing cognitive impairment and with Montreal Cognitive Assessment (MoCA) data. Read More

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http://dx.doi.org/10.1007/s00415-019-09256-6DOI Listing
May 2019
2 Reads

Ablative fractional resurfacing in acute care management of facial burns: a new approach to minimise the need for acute surgical reconstruction.

J Burn Care Res 2019 Mar 7. Epub 2019 Mar 7.

Burns Unit, Hospital Rd, Concord Repatriation General Hospital, Sydney NSW Australia.

Background: Current evidence suggests awaiting for scars to fully mature prior to engaging surgical reconstruction unless acute indications to prevent secondary damage, such as microstomia and eyelid ectropion are apparent.

Aim: To evaluate the efficacy of ablative fractional CO2 laser intervention early in the acute treatment of panfacial burn injury.

Methods: A 39-year old Asian male with 60% TBSA flame burns including panfacial involvement was developing microstomia and upper and lower eyelid ectropion early proceeding epithelialization. Read More

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http://dx.doi.org/10.1093/jbcr/irz030DOI Listing

A comparison of contracture severity at acute discharge in patients with and without heterotopic ossification: A Burn Model System National Database Study.

J Burn Care Res 2019 Mar 6. Epub 2019 Mar 6.

Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, MA.

Objective: This study assesses the association between heterotopic ossification and upper extremity contracture by comparing goniometric measured active range of motion outcomes of patients with and without heterotopic ossification.

Methods: Data was obtained from the Burn Model System National Database between 1994 and 2003 for patients over 18 years with elbow contracture at acute discharge. Absolute losses in elbow range of motion were compared for those with and without radiologic evidence of heterotopic ossification (location undefined) and were further examined by burn size subgroups using Wilcoxon rank-sum test. Read More

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http://dx.doi.org/10.1093/jbcr/irz031DOI Listing
March 2019
1 Read

Triage Systems in Mass Casualty Incidents and Disasters: A Review Study with A Worldwide Approach.

Open Access Maced J Med Sci 2019 Feb 12;7(3):482-494. Epub 2019 Feb 12.

Health in Emergency and Disaster Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

Background: Injuries caused by emergencies and accidents are increasing in the world. To prioritise patients to provide them with proper services and to optimally use the resources and facilities of the medical centres during accidents, the use of triage systems, which are one of the key principles of accident management, seems essential.

Aim: This study is an attempt to identify available triage systems and compare the differences and similarities of the standards of these systems during emergencies and disasters through a review study. Read More

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http://dx.doi.org/10.3889/oamjms.2019.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390156PMC
February 2019
3 Reads

An effective procedure for skin stiffness measurement to improve Paediatric Burn Care.

Burns 2019 Mar 1. Epub 2019 Mar 1.

Pediatric Burn Center, Division of Plastic and Reconstructive Surgery, University Children's Hospital Zurich, Steinwiesstrasse 75, 8032 Zurich, Switzerland. Electronic address:

Background: The objective evaluation of scar quality plays a crucial role in improving burn surgery and scar rehabilitation. Suction-based skin measurements were proposed as a method to objectively determine the mechanical properties of scars, yet their use is limited, in particular for paediatric burn care. A new device was developed which provides essential advantages for scar assessment. Read More

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http://dx.doi.org/10.1016/j.burns.2019.02.004DOI Listing

Noninvasive Ventilation: Education and Training. A Narrative Analysis and an International Consensus Document.

Adv Respir Med 2019 Mar 4. Epub 2019 Mar 4.

Intensive Care Unit. Hospital Morales Meseguer Murcia, Murcia, 30008, Spain.

Background: Noninvasive ventilation (NIV) is an increasingly used method of respiratory support. The use of the NIV is expanding over the time and if properly used, it can save patients life and improve long-term prognosis. However, both knowledge and skills for its proper use as a life-support are paramount. Read More

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http://dx.doi.org/10.5603/ARM.a2019.0006DOI Listing
March 2019
4 Reads

Epidemiology of Cervical Injuries in NCAA Football Players.

Spine (Phila Pa 1976) 2019 Feb 28. Epub 2019 Feb 28.

Department of Orthopedic Surgery, Mayo Clinic Arizona.

MINI: The incidence and etiology of cervical spine injuries in National Collegiate Athletic Association (NCAA) football players has not been well defined in recent years. The rate of significant and disabling cervical spine injuries appears to be low in the NCAA football athlete.

Study Design: Descriptive epidemiology study. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003008DOI Listing
February 2019
4 Reads

Impacts of low-energy extracorporeal shockwave therapy on pain, pruritus, and health-related quality of life in patients with burn: A randomized placebo-controlled study.

Burns 2019 Feb 28. Epub 2019 Feb 28.

Department of Physical Therapy, New Kasr El-Aini Teaching Hospital, Faculty of Medicine, Cairo University, Egypt; Department of Physical Therapy and Health Rehabilitation, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, Saudi Arabia.

Background: The management of post-burn pain and pruritus remain a potent challenge because of their bad effects on health-related quality of life (HRQOL). The main purpose of this study was to evaluate the impacts of low-energy extracorporeal shockwave therapy (low-energy ESWT) in the management of pain, pruritus, and HRQOL in patients with burn.

Methods: Forty-five adult patients with burn, their age ranged from 18 to 55 years, were included in the study, they randomly assigned into 22 patients in the study group (low-energy ESWT) and 23 patients in the placebo group. Read More

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http://dx.doi.org/10.1016/j.burns.2019.02.007DOI Listing
February 2019
1 Read

Vision Rehabilitation with a Native Pintucci-type Keratoprosthesis.

J Ophthalmic Vis Res 2019 Jan-Mar;14(1):101-104

Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: To report visual rehabilitation with a native Pintucci keratoprosthesis (KPro) after a severe ocular surface chemical burn in a male patient.

Case Report: A 41-year-old man experienced a bilateral severe chemical burn 5 years previously. Earlier penetrating keratoplasty and keratolimbal allografts were unsuccessful in both eyes, and neither of the eyes had vision better than light perception. Read More

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http://dx.doi.org/10.4103/jovr.jovr_52_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388536PMC

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gena Roschupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 03 28;51(3):414-430. Epub 2019 Feb 28.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

Risk for late-onset Alzheimer's disease (LOAD), the most prevalent dementia, is partially driven by genetics. To identify LOAD risk loci, we performed a large genome-wide association meta-analysis of clinically diagnosed LOAD (94,437 individuals). We confirm 20 previous LOAD risk loci and identify five new genome-wide loci (IQCK, ACE, ADAM10, ADAMTS1, and WWOX), two of which (ADAM10, ACE) were identified in a recent genome-wide association (GWAS)-by-familial-proxy of Alzheimer's or dementia. Read More

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http://dx.doi.org/10.1038/s41588-019-0358-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463297PMC
March 2019
15 Reads
29.352 Impact Factor

Keratinocyte electrotaxis induced by physiological pulsed direct current electric fields.

Bioelectrochemistry 2019 Jun 14;127:113-124. Epub 2019 Feb 14.

Department of Plastic and Cosmetic Surgery, State Key Laboratory of Trauma, Burns and Combined Injury, Southwest Hospital, The Third Military Medical University (Army Medical University), Chongqing, China. Electronic address:

Endogenous electric fields (EFs) direct the migration (electrotaxis) of keratinocytes in skin wounds, and the exogenous application of EFs may therefore improve wound healing, but the potential benefits are limited by the side effects of constant direct current (DC) passing through tissues. In contrast, with pulsed DC (characterized by intermittent output), parameters can be adjusted to minimize the adverse effects of electric currents. However, it remains unknown whether pulsed DC can reliably induce keratinocyte electrotaxis. Read More

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http://dx.doi.org/10.1016/j.bioelechem.2019.02.001DOI Listing
June 2019
2 Reads

The association between postburn vitamin D deficiency and the biomechanical properties of hypertrophic scars.

J Burn Care Res 2019 Feb 26. Epub 2019 Feb 26.

Department of Physical Medicine and Rehabilitation, Hallym University Sacred Heart Hospital, Hallym University College of Medicine.

Fibroblasts, keratinocytes, mast cells, and other cells participate in hypertrophic scar formation and express the vitamin D receptor. We investigated the association between vitamin D deficiency and the biomechanical properties of hypertrophic burn scars. This cross-sectional study analyzed 486 participants enrolled from May 1, 2013 to April 30, 2017. Read More

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http://dx.doi.org/10.1093/jbcr/irz028DOI Listing
February 2019
1 Read

[A brief history of burn rehabilitation medicine in China].

Authors:
J Wu Y Z Wang

Zhonghua Shao Shang Za Zhi 2019 Feb;35(2):81-85

Department of Burns, the Air Force Hospital of the Central Theater of the PLA, Datong 037006, China.

Burn rehabilitation medicine in China has made great progress in recent years. This article reviews the development history of burn rehabilitation medicine in China from three stages of the initial period, the starting stage, and the development period by looking back to the history. Besides, the article is written according to the milestone events in the development of burn rehabilitation medicine, such as article publishing, guideline making, monograph publication, establishment of rehabilitation association, rehabilitation conference holding. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1009-2587.2019.02.001DOI Listing
February 2019

Long-Term Oxygen Therapy.

Dtsch Arztebl Int 2018 12;115(51-52):871-877

Institute for Pulmonary Rehabilitation Research, Schoen Klinik Berchtesgadener Land, Schoenau am Koenigssee; Philipps University Marburg (Schoenau site), German Center for Lung Research (DZL), Marburg; Department for Prevention, Rehabilitation, and Sports Medicine, Technical University Munich (TUM), Munich, Germany.

Background: Long-term oxygen therapy (LTOT) is an established treatment for patients with chronic hypoxemia. Its scientific basis is derived mainly from two trials from the early 1980s that showed a survival advantage for patients with chronic obstructive pulmonary disease (COPD) treated with LTOT. Robust data are not available for other diseases associated with hypoxemia. Read More

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http://dx.doi.org/10.3238/arztebl.2018.0871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381774PMC
December 2018
3 Reads

Physiological Stress in Rescued Wild Koalas Are Influenced by Habitat Demographics, Environmental Stressors, and Clinical Intervention.

Front Endocrinol (Lausanne) 2019 29;10:18. Epub 2019 Jan 29.

School of Animal and Veterinary Sciences, Charles Sturt University, Wagga Wagga, NSW, Australia.

Koalas are rescued from the wild often with incidence of burns from bushfire, injury from animal attacks, vehicle collision, and diseases. Exposure to environmental stressors (trauma and disease) could generate physiological stress and potentially impact the outcomes of clinical management intervention and rehabilitation of rescued wild koalas. It is important to quantify the stress physiology of wild koalas upon registering into clinical care. Read More

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http://dx.doi.org/10.3389/fendo.2019.00018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361754PMC
January 2019

A review and evaluation of patient-reported outcome measures for spasticity in persons with spinal cord damage: Recommendations from the Ability Network - an international initiative.

J Spinal Cord Med 2019 Feb 13:1-11. Epub 2019 Feb 13.

e Division of Physiatry, Division of Medicine , University of Toronto , Toronto , Canada.

Context: Patient-reported outcome measures (PROMs) are valuable for capturing the impact of spasticity on health-related quality of life (HRQoL) in persons with spinal cord damage (SCD) and evaluating the efficacy of interventions.

Objective: To provide practical guidance for measuring HRQoL in persons with spasticity following SCD.

Methods: Literature reviews identified measures of HRQoL and caregiver burden, utilized in studies addressing spasticity in SCD. Read More

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http://dx.doi.org/10.1080/10790268.2019.1575533DOI Listing
February 2019
1 Read

Second-degree Skin Burn from A Radiofrequency Grounding Pad: A Case Report and Review of Risk Mitigation Strategies.

PM R 2019 Feb 11. Epub 2019 Feb 11.

University of Utah, Department of Physical Medicine and Rehabilitation, Salt Lake City, UT.

Thermal radiofrequency neurotomy (RFN) is used for a variety of indications. Thermal energy is used to thermocoagulate a target structure. Current introduced into the body through the RFN electrode exits the body via an electrical dispersive pad (EDP). Read More

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http://dx.doi.org/10.1002/pmrj.12143DOI Listing
February 2019
5 Reads

Classification of Mild Stroke: A Mapping Review.

PM R 2019 Feb 11. Epub 2019 Feb 11.

B.R.A.I.N. Laboratory (Better Rehabilitation and Assessment for Improved Neurorecovery); Division of Occupational Therapy, The Ohio State University, Columbus, OH.

Persons with mild stroke experience motor and cognitive impairments that negatively impact their health and quality of life. To address these deficits, it is essential for clinicians and researchers to precisely identify mild stroke survivors. Despite the fact that half of all strokes are categorized as mild, no standards exist on what constitutes a "mild" stroke. Read More

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http://dx.doi.org/10.1002/pmrj.12142DOI Listing
February 2019
7 Reads
1.662 Impact Factor

Head and neck burns are associated with long-term patient-reported dissatisfaction with appearance: A Burn Model System National Database study.

Burns 2019 Mar 4;45(2):293-302. Epub 2019 Feb 4.

Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Charlestown, MA, United States. Electronic address:

Introduction: Burns affecting the head and neck (H&N) can lead to significant changes in appearance. It is postulated that such injuries have a negative impact on patients' social functioning, quality of life, physical health, and satisfaction with appearance, but there has been little investigation of these effects using patient reported outcome measures. This study evaluates the effect of H&N burns on long-term patient reported outcomes compared to patients who sustained burns to other areas. Read More

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http://dx.doi.org/10.1016/j.burns.2018.12.017DOI Listing
March 2019
1 Read

The Presence of Scarring and Associated Morbidity in the Burn Model System National Database.

Ann Plast Surg 2019 Mar;82(3 Suppl 2):S162-S168

Spaulding Rehabilitation Hospital/Harvard Medical School, Boston, MA.

Introduction: Postburn scarring is common, but the risk factors, natural history, and consequences of such scars are still poorly understood. This study aims to describe the frequency of scar-related morbidity for up to 2 years after injury and to analyze the impact of burn scars on long-term functional, psychosocial, and reintegration outcomes.

Methods: Analysis was conducted on data collected between January 2006 and May 2014 from 960 patients (2440 anatomic burn sites) using the Burn Model System (BMS) database. Read More

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http://dx.doi.org/10.1097/SAP.0000000000001826DOI Listing
March 2019
2 Reads

Work-related burn injuries and claims for post-traumatic stress disorder in Korea.

Burns 2019 Mar 2;45(2):461-465. Epub 2019 Feb 2.

Department of Psychiatry, Hangang Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Republic of Korea. Electronic address:

Objective: The objective of this study is to broaden our understanding of psychiatric disorders due to work-related burn injury compensated by the Industrial Accident Compensation Insurance operated by the Korea Workers' Compensation and Welfare Service (KCOMWEL).

Methods: Using the KCOMWEL electronic database, we collected data on psychiatric disorders due to work-related burn injury based on workers' compensation records from 2005 to 2014 and analyzed the characteristics of the claims.

Results: The average number of claims per year for post-traumatic stress disorder was 67 and the approval rate from 2005 to 2014 was 53. Read More

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http://dx.doi.org/10.1016/j.burns.2018.08.016DOI Listing
March 2019
2 Reads

Early Protocolized Versus Usual Care Rehabilitation for Pediatric Neurocritical Care Patients: A Randomized Controlled Trial.

Pediatr Crit Care Med 2019 Jan 30. Epub 2019 Jan 30.

Department of Critical Care Medicine, UPMC Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Objectives: Few feasibility, safety, and efficacy data exist regarding ICU-based rehabilitative services for children. We hypothesized that early protocolized assessment and therapy would be feasible and safe versus usual care in pediatric neurocritical care patients.

Design: Randomized controlled trial. Read More

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http://dx.doi.org/10.1097/PCC.0000000000001881DOI Listing
January 2019
4 Reads

Racial and Ethnic Disparities in Discharge to Rehabilitation Following Burn Injury.

J Burn Care Res 2019 Feb;40(2):143-147

Department of Surgery, University of North Carolina at Chapel Hill, North Carolina Jaycee Burn Center, Chapel Hill, North Carolina.

Racial and ethnic disparities in access to inpatient rehabilitation have been previously described for various injury groups; however, no studies have evaluated whether such disparities exist among burn patients. Their aim was to determine if racial disparities in discharge destination (inpatient rehabilitation, skilled nursing facility, home with home health, or home) following burn injury existed in this single-institution study. A retrospective analysis of all adult burn patients admitted to UNC Jaycee Burn Center from 2002 to 2012 was conducted. Read More

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http://dx.doi.org/10.1093/jbcr/irz001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382405PMC
February 2019
13 Reads

Dysphagia in the burn patient: Experience in a National Burn Reference Centre.

Burns 2019 Jan 25. Epub 2019 Jan 25.

Department of Speech, Language and Hearing Sciences, Faculty of Medicine, Universidad de Chile, Santiago, Chile.

Introduction: Major burn patients are exposed to different invasive procedures for wound management or medical stabilization. Dysphagia is a frequent adverse effect of burns in the presence of invasive airway procedures and facial wounds.

Objective: To estimate the prevalence of dysphagia, to determine the degree of severity, and to report clinical characteristics that could contribute to the appearance of dysphagia in patients admitted to a National Burn Reference Centre. Read More

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http://dx.doi.org/10.1016/j.burns.2019.01.002DOI Listing
January 2019
2 Reads

Patient-Reported Outcome Measures for Toe-to-Hand Transfer: A Prospective Longitudinal Study.

Plast Reconstr Surg 2019 Apr;143(4):1122-1132

Taipei, Taiwan From the Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung Medical College and Chang Gung University.

Background: Patient-reported outcome measures are an important metric in evaluating treatment efficacy of reconstructive surgery. Toe-to-hand transfer can restore vital prehensile function; however, this surgery is complex, extensive rehabilitation is required, and there are concerns about donor-site morbidity. This study longitudinally explores the benefits of this procedure, from the patient's perspective, using patient-reported outcome measures. Read More

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http://dx.doi.org/10.1097/PRS.0000000000005422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438721PMC
April 2019
4 Reads