Bullous Pemphigoid Triggered by Thermal Burn Under Medication With a Dipeptidyl Peptidase-IV Inhibitor: A Case Report and Review of the Literature.
- Yosuke Mai,
- Wataru Nishie,
- Kazumasa Sato,
- Moeko Hotta,
- Kentaro Izumi,
- Kei Ito,
- Kazuyoshi Hosokawa,
- Hiroshi Shimizu
Front Immunol 2018 12;9:542. Epub 2018 Apr 12.
Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Bullous pemphigoid (BP) is a common autoimmune blistering disease in which autoantibodies mainly target the hemidesmosomal component BP180 (also known as type XVII collagen) in basal keratinocytes. Various triggering factors are known to induce BP onset, including radiotherapy, burns, ultraviolet exposure, surgery, and the use of dipeptidyl peptidase-IV inhibitors (DPP4i), which are widely used antihyperglycemic drugs. Here, we present a case of BP triggered by a thermal burn under medication with DPP4i. Read More