6,449 results match your criteria Bulletin Du Cancer[Journal]


[COVID-19 and cancers. Summary of French guidelines from medical societies and their evolution].

Authors:
Manuel Rodrigues

Bull Cancer 2020 05;107(5):521-523

Institut Curie, PSL research university, département d'oncologie médicale, 75005 Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255101PMC

[Ten years of advances in head and neck surgery, how does this influence postoperative radiotherapy?]

Bull Cancer 2020 May 26. Epub 2020 May 26.

Centre François-Baclesse, département de chirurgie ORL, 3, avenue Général Harris, 14000 Caen, France; CHU, département de chirurgie ORL, 3, avenue Général Harris, 14000 Caen, France.

Minimal invasive surgery and reconstructive surgery tend to become the standard in France in the management of head and neck tumors. The use of endoscopic approaches (through endoscopic endonasal/transoral approaches±robot-assisted) instead of open surgery and the use of reconstructive surgery using autologous (flaps) or heterologous materials aim to reduce surgical morbidity by making-up for the loss of substance to restore the function. The impact of these substantial changes in surgical techniques has not been assessed with respect to postoperative radiotherapy practice. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.04.011DOI Listing

[Mechanisms of radiation-induced lymphopenia and therapeutic impact].

Bull Cancer 2020 May 22. Epub 2020 May 22.

Centre François-Baclesse/ARCHADE, département de radiothérapie, 3, avenue General Harris, 14000 Caen, France; Laboratoire de physique corpusculaire IN2P3/ENSICAEN - UMR6534, Caen, France; Normandie University, UNICAEN, Caen, France. Electronic address:

Radiation induced lymphopenia is frequent and can be severe and durable. Although lymphocytes have long been known as highly radiosensitive cells, it is poorly characterized. Radiation-induced lymphopenia seems to affect lymphocyte subpopulations differently and seems to be influenced by radiation modalities. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.04.009DOI Listing

[COVID-19 impact on the cancer care structuration: example of the multidisciplinary team meeting dedicated to oncology in Occitanie].

Bull Cancer 2020 May 18. Epub 2020 May 18.

Registre des Cancers du Tarn, BP 37, 81001 Albi Cedex, France.

This work examines the impact of the SARS-CoV2 epidemic and the organizational recommendations that have been issued since March 16 on tumor boards (TB) activity. The tumor board activity was measured from tumor board sheets extracted from the oncologic electronic file between January 7, 2019 and April 24, 2020. The pre-containment activity was compared to the activity of the containment periods but also to the equivalent periods in 2019. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231733PMC

[Prevention and treatment of antineoplastic drug-induced nausea and vomiting in pediatric onco-hematology: An update].

Bull Cancer 2020 May 14. Epub 2020 May 14.

CHU Reims, service pharmacie, avenue du Général-Koenig, 51100 Reims, France; Université de Reims Champagne-Ardenne, faculté de pharmacie de Reims, 51, rue Cognacq-Jay, 51100 Reims, France.

Antineoplastic drug induced nausea and vomiting are common adverse events in cancer care of paediatric patients ; therefore, prevention and management of these adverse events is a major concern for healthcare professionals. There are common features between paediatric and adult patients in terms of the emetogenic level depending on antineoplastic agents or about available medicines. However, there are also specificities for paediatric population including individual risk factors of emesis or nausea assessment for example. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.03.015DOI Listing

[Effect of activities profile variations on health-related quality of life among breast cancer patients: Secondary exploratory analysis from PASAPAS study data].

Bull Cancer 2020 May 13. Epub 2020 May 13.

Centre Léon Bérard, département cancer environnement, 28, rue Laennec, 69008 Lyon, France; Centre de recherche en cancérologie de Lyon, UMR, Inserm 1052, CNRS 5286 CLB, 28, rue Laennec, 69008 Lyon, France.

Introduction: Lifestyle changes in breast cancer patients, by physical activity increasing, are becoming a main objective in supportive care. The objective of this study was to explore the impact of the daily activity profile evolution on the quality of life among this public.

Methods: Sixty patients (18 to 75 years) with non-metastatic breast cancer were randomized to a 2:1 ratio (physical activity intervention; control) in the PASAPAS randomized clinical trial. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.03.014DOI Listing

[Clinical trials during pandemic crisis: How to ensure safety and maintain access to innovation].

Bull Cancer 2020 May 7. Epub 2020 May 7.

Agence Nationale de Sécurité du Médicament et des Produits de Santé (ANSM), 143-147, boulevard Anatole France, 93285 Saint-Denis cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203020PMC

[Development of a grid for characterizing structures offering adapted physical activity programs for people who have had cancer].

Bull Cancer 2020 May 12;107(5):556-564. Epub 2020 May 12.

Département cancer environnement, centre Léon-Bérard (CLB), Lyon, France; Plateforme Activ'RA, Activité physique contre le cancer en Rhône Alpes, Lyon, France; EA 7425 HESPER, Health Services and Performance Research, Lyon, France. Electronic address:

As the benefits of physical activity (PA) in oncology field continue to be demonstrated, multiple structures (sports clubs, associations…) develop PA programs and activities to offer cancer patients survivors the opportunity to continue adapted physical activity. Promoted in the 2014-2019 cancer plan as complementary supportive care, the practice of physical activity is legitimized by the 2016 Health Act of the Ministry of Social Affairs and Health, including the amendment 'prescription health sport', by giving it a legislative framework. In this context of development of new PA offers for cancer patients, it seems necessary to determine and evaluate the structures on their capacities to supervise physical activities for this population with specific needs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.03.011DOI Listing

[Impact of the COVID-19 epidemic on requests for initial care for breast cancer].

Bull Cancer 2020 Apr 30. Epub 2020 Apr 30.

Institut Curie, département d'oncologie médicale, 26, rue d'Ulm, 75005 Paris, France; Institut Curie, département d'oncologie médicale, 26, rue d'Ulm, 75005 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190490PMC

[SARS-CoV-2 and cancer in France: Resident in oncology on the front line. Testimony of residents in oncology in two French clusters: Grand-Est and Île-de-France].

Bull Cancer 2020 Apr 24. Epub 2020 Apr 24.

AERIO , Association pour l'Enseignement et le Recherche des Internes en Oncologie, 149 avenue du Maine, 75014 Paris.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181988PMC

COVID-19 and acute lymphoblastic leukemias of children and adolescents: First recommendations of the Leukemia committee of the French Society for the fight against Cancers and Leukemias in children and adolescents (SFCE).

Bull Cancer 2020 Apr 30. Epub 2020 Apr 30.

Hôpital Universitaire Robert-Debré AP-HP, Université de Paris, service d'hémato-immunologie pédiatrique, Paris, France.

Since the emergence of the SARS-CoV-2 infection, many recommendations have been made. However, the very nature of acute lymphoblastic leukemias and their treatment in children and adolescents led the Leukemia Committee of the French Society for the fight against cancers and leukemias in children and adolescents (SFCE) to propose more specific recommendations, even if data for this population are still scarce. They may have to evolve according to the rapid evolution of knowledge on COVID-19. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190519PMC

[Access to fertility preservation for adolescents and young adults aged 15 to 24 years with cancers in Auvergne, France].

Bull Cancer 2020 May 6. Epub 2020 May 6.

CHU de Clermont-Ferrand, hôpital Estaing, service d'hématologie-oncologie pédiatrique, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand, France; Université Clermont-Auvergne, Inserm-CIC 1405, unité CRECHE, Clermont-Ferrand, France. Electronic address:

Introduction: Cancers of adolescents and young adults have particular epidemiological specificities. The improvement in their survival should be accompanied by an increased consideration of the treatments' side effects, among which the potential decrease in fertility. The objective of the study was to describe the access to fertility preservation of these patients at the University Hospital of Clermont-Ferrand over a period of 3 years. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.03.013DOI Listing

[Awareness on the law of bioethics].

Bull Cancer 2020 May 30;107(5):541-542. Epub 2020 Apr 30.

CHU/IUCT-O, 31059 Toulouse, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.04.005DOI Listing

[MUTYH-associated polyposis: Review and update of the French recommendations established in 2012 under the auspices of the National Cancer Institute (INCa)].

Bull Cancer 2020 May 1;107(5):586-600. Epub 2020 May 1.

PSL Research University, Institut Curie, département de génétique, 26, rue d'Ulm, 75248 Paris cedex 05, France. Electronic address:

MUTYH-associated polyposis (MUTYH-associated polyposis, MAP) is an autosomal recessive inheritance disorder related to bi-allelic constitutional pathogenic variants of the MUTYH gene which was first described in 2002. In 2011, a group of French experts composed of clinicians and biologists, performed a summary of the available data on this condition and drew up recommendations concerning the indications and the modalities of molecular analysis of the MUTYH gene in index cases and their relatives, as well as the management of affected individuals. In view of recent developments, some recommendations have become obsolete, in particular with regard to the molecular analysis strategy since MUTYH gene has been recently included in a consensus panel of 14 genes predisposing to colorectal cancer. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.02.004DOI Listing

Reducing the seroma volume by quilting suture after breast reconstruction with a latissimus dorsi flap: Single institutional experience.

Bull Cancer 2020 May 28;107(5):543-550. Epub 2020 Apr 28.

Centre Oscar Lambret, breast surgery unit, 3, rue Combemale, 59020 Lille cedex, France. Electronic address:

Introduction: After breast reconstruction (BR) with latissimus dorsi flap (LDF) postoperative seroma is a frequent source of functional discomfort. The aim of this study was to evaluate the quilting suture on reducing the seroma volume by reducing the dead space created by LDF harvest for BR.

Material And Methods: This retrospective monocenter study was designed to compare patients who underwent BR using LDF with or without quilting suture. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.03.006DOI Listing

[COVID 19 and cancer: What are the consequences of the cancer care reorganization?]

Bull Cancer 2020 05 23;107(5):538-540. Epub 2020 Apr 23.

CHRU de Lille, département d'oncologie médicale, Lille, France; Université de Lille, Lille, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.04.001DOI Listing

[Covid-19, the Société française du cancer (SFC) and the BulletinduCancer].

Authors:
Manuel Rodrigues

Bull Cancer 2020 Apr;107(4):393-394

Institut Curie, PSL research university, département d'oncologie médicale, 75005 Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175863PMC

[Freedom, equality, fraternity facing the COVID-19].

Bull Cancer 2020 Apr;107(4):391-392

Université Côte-d'Azur, institut de biologie Valrose, CNRS, Inserm, 06108 Nice cedex 2, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175899PMC

[French Society for Surgical Oncology (SFCO) guidelines for the management of surgical oncology in the pandemic context of COVID 19].

Bull Cancer 2020 05 6;107(5):524-527. Epub 2020 Apr 6.

Université de Montpellier, institut de cancérologie de Montpellier (ICM), département de chirurgie oncologique, Montpellier, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135219PMC

[Diagnosis, prognosis and treatment of sinonasal carcinomas (excluding melanomas, sarcomas and lymphomas)].

Bull Cancer 2020 May 15;107(5):601-611. Epub 2020 Apr 15.

French Rare Head and Neck Cancer Expert Network, France.

Sinonasal carcinomas account for 3% of ENT cancers. They are subdivided into squamous cell carcinomas (50%), adenocarcinomas [20%, mostly of intestinal type (ITAC)], and more rarely, adenoid cystic carcinomas, olfactory neuroblastomas (=esthesioneuroblastomas), neuroendocrine carcinomas or undifferentiated sinonasal carcinomas (SNUC). The 5-year survival rates are, in descending order, 72% for neuroblastomas, 63% for adenocarcinomas, 50-60% for large-cell neuroendocrine carcinomas, 53% for squamous cell carcinomas, 25-50% for adenoid cystic, 35% for small-cell neuroendocrine carcinomas and 35% for SNUC and newly discovered histologies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.02.013DOI Listing
May 2020
0.635 Impact Factor

[Retroperitoneal lymph node assessment in pediatric paratesticular rhabdomyosarcoma].

Bull Cancer 2020 Apr 14. Epub 2020 Apr 14.

Hôpital Bicêtre, Assistance publique-Hôpitaux de Paris, université Paris-Saclay, chirurgie pédiatrique, 78, rue du Général-Leclerc, 94270 Le Kremlin-Bicêtre, France.

Paratesticular Rhabdomyosarcoma accounts for 7 to 11% of pediatric rhabdomyosarcomas. Children older than 10 years have a worse event-free survival (69 to 80% vs. 87 to 92%) than children younger than 10 years. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.03.007DOI Listing

[Intratumoral B cells and tertiary lymphoid structures are biomarkers of survival and immunotherapy responses].

Bull Cancer 2020 Apr 10;107(4):403-404. Epub 2020 Apr 10.

Université de Paris, Sorbonne Université, Centre de Recherche des Cordeliers, Inserm, 15, rue de l'École-de-Médecine, 75006 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.02.008DOI Listing

[The role of direct oral anticoagulants in the management of cancer-associated thrombosis in 2020].

Bull Cancer 2020 May 3;107(5):574-585. Epub 2020 Apr 3.

Université de Paris, Innovative Therapies in Haemostasis, Inserm, 75006 Paris, France; AH-HP, Hôpital européen Georges Pompidou, service d'hématologie biologique et laboratoire de recherches biochirurgicales (fondation Carpentier), 75015 Paris, France. Electronic address:

Direct oral anticoagulants, anti-IIa or anti-Xa, are widely used in the treatment and prevention of venous thromboembolic disease as well as in nonvalvular atrial fibrillation. Direct oral anticoagulants are characterized by a rapid onset of activity, a predictable response and a relatively wide therapeutic window. Nevertheless, theoretical drug interactions exist since direct oral anticoagulants are substrates of the transport protein P-glycoprotein and/or of isoforms of cytochromes P450 pathway. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.02.010DOI Listing

[Impact of the LACC study. A SFOG survey].

Bull Cancer 2020 May 31;107(5):551-555. Epub 2020 Mar 31.

Département de chirurgie, Gustave Roussy Cancer Campus, 94800 Villejuif, France.

Introduction: The LACC (Laparoscopic Approach to Cervical Cancer Trial) study, released in 2018, described oncological findings in favour of open surgery compared to the minimally invasive pathway in the management of early stage cervical cancers. Our aim was to assess the impact of this study on surgical practices in France.

Method: Online questionnaire, consisting of 13 questions addressed to gynecology oncology french society (SFOG) surgeons. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.02.012DOI Listing
May 2020
0.635 Impact Factor

[Carbon footprint and cancer: Time for green oncology?]

Bull Cancer 2020 May 31;107(5):612-613. Epub 2020 Mar 31.

Institut Curie, 35 rue Dailly, 92210 Saint-Cloud, France; UFR des Sciences de la santé Simone Veil (Université de Versailles SQY), Université Paris Saclay, Versailles France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.02.009DOI Listing

[High fidelity simulation training for medical oncology announcement consultation].

Bull Cancer 2020 Apr 31;107(4):417-427. Epub 2020 Mar 31.

Hôpital des Enfants, service de chirurgie viscérale pédiatrique, 8, avenue Dominique-Larrey, 87042 Limoges cedex, France; Faculté de médecine de Limoges, département universitaire d'enseignement numérique en santé, 2, rue du Docteur-Marcland, 87025 Limoges cedex, France.

Introduction: Medical oncology bad news consultation is a particularly stressful situation for both the patient and the physician. High-fidelity simulation is a learning option that has never been evaluated in France in this field.

Materials And Methods: This is a feedback from simulated announcement consultations carried out from January 2018 to May 2019. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.02.007DOI Listing

[Comparative effectiveness of proton therapy versus photon therapy as part of concurrent chemo-radiotherapy for locally advanced cancer].

Bull Cancer 2020 04 31;107(4):405-407. Epub 2020 Mar 31.

Centre François Baclesse, 3, avenue du Général Harris, 14000 Caen, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.02.011DOI Listing

[Therapeutic options for genitourinary cancers during the epidemic period of COVID-19].

Authors:
Karim Fizazi

Bull Cancer 2020 Apr 27;107(4):395-397. Epub 2020 Mar 27.

Institut Gustave-Roussy, département de médecine oncologique, 114, rue Édouard-Vaillant, 94800 Villejuif, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195090PMC

[Adaptive radiotherapy for nasopharyngeal carcinomas: Where are we?]

Bull Cancer 2020 May 31;107(5):565-573. Epub 2020 Mar 31.

CHU d'Habib-Bourguiba, service de radiothérapie carcinologique, Sfax, Tunisie; Université de Sfax, Sfax, Tunisie.

Modern high-precision radiotherapy techniques have recently incorporated the notion of anatomical variations of the patient during treatment and have tried to adapt the treatment planning to them. Adaptive radiotherapy for nasopharyngeal tumors is starting to prove its benefit nowadays. His interest is constantly being evaluated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2019.12.013DOI Listing

Cancer prevalence, incidence and mortality rates in Pakistan in 2018.

Bull Cancer 2020 Apr 26;107(4):517-518. Epub 2020 Mar 26.

Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2019.12.011DOI Listing

[Better screening for work-related cancers: The experience of Brest University Hospital Occupational Disease Center inpatient service].

Bull Cancer 2020 Apr 20;107(4):428-437. Epub 2020 Mar 20.

Université de Bretagne Occidentale, LABERS, EA 3149, 22, avenue Camille-Desmoulins, CS 93837, 29238 Brest cedex 3, France; University of Alberta, Faculty of Medicine and Dentistry, Department of Medicine, Division of Preventive Medicine, Edmonton, AB, Canada.

Introduction: An in-patient clinical service has been set up in March 2016 in the Occupational Diseases Center of Brest University Hospital, France, to seek for work-relatedness of diseases in patients hospitalized into the oncology and hematology departments. We present here data after two years of existence.

Methods: All cases of cancers or malignant hematological diseases (ICD-10 codes C00 to C97 and D37 to D48) seen between March 1, 2016, and March 1, 2018, have been identified. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.01.013DOI Listing

[Checkpoint inhibitors-induced hypophysitis].

Bull Cancer 2020 Apr 19;107(4):490-498. Epub 2020 Mar 19.

Hospices civils de Lyon, fédération d'endocrinologie, 28, avenue Doyen-Lépine, 69677 Bron cedex, France; ImmuCare, institut de cancérologie des hospices civils de Lyon (IDCRC-HCL), Lyon, France; Université de Lyon, université Claude-Bernard-Lyon-1, Lyon, France.

Checkpoint inhibitors immunotherapy is more and more prescribed in oncology, causing new immune related endocrine adverse events. Hypophysitis occurs in approximately 10 % of patients treated with anti-CTLA4. It occurs two to three months after initiation of the immunotherapy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.01.012DOI Listing

[Proteinuria in multiple myeloma: Be careful to iatrogeny].

Bull Cancer 2020 Apr 13;107(4):519-520. Epub 2020 Mar 13.

Institut de cancérologie Lucien-Neuwirth, département d'hématologie clinique, 42270 Saint-Priest-en-Jarez, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.01.014DOI Listing

[Desmoid type fibromatosis, from radical excision to molecular extirpation].

Bull Cancer 2020 Mar;107(3):344-345

Institut Curie, PSL university, SIREDO Oncology Center (Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer), 26, rue d'Ulm, 75005 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.02.006DOI Listing
March 2020
0.635 Impact Factor

[Taking care, right here, right now: Why medicine should be inspired by the philosophy of Albert Camus?]

Authors:
François Blot

Bull Cancer 2020 Mar;107(3):289-291

Comité d'éthique, Gustave Roussy Cancer Campus - université Paris Saclay, 114, rue Edouard-Vaillant, 94805 Villejuif cedex, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.02.005DOI Listing

Comprehensive tumor profiling-guided therapy in rare or refractory solid cancer: A feasibility study in daily clinical practice.

Bull Cancer 2020 Apr 4;107(4):410-416. Epub 2020 Mar 4.

Saint-Joseph University, School of Medicine, Department of Oncology and Hematology, Beirut, Lebanon.

Tumor profiling has been shown to benefit patients with rare or refractory metastatic cancer, but several limitations hamper its use in daily clinical practice. We aim to assess the added benefit of a comprehensive tumor profiling, including factors predictive of response to targeted and cytotoxic therapy, in the treatment of refractory or rare solid tumors outside of a formal clinical trial. Patients were included between 2013 and 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2019.12.010DOI Listing
April 2020
0.635 Impact Factor

[Androgen receptor-positive triple negative breast cancer: From biology to therapy].

Authors:
Thomas Grellety

Bull Cancer 2020 Apr 4;107(4):506-516. Epub 2020 Mar 4.

Centre hospitalier de la Côte Basque, service d'oncologie médicale, 13, avenue de l'Interne Jacques-Loeb, 64100 Bayonne, France; Institut Bergonié, département d'oncologie médicale, 229, cours de l'Argonne, 33076 Bordeaux, France. Electronic address:

A subgroup of androgen receptor-expressing tumors represents approximately 30 % of all triple negative tumors. The androgen receptor and its signaling pathways have a central biological role in this tumor entity. These triple negative androgen receptor-positive tumors occur in older patients and do not appear to have a better prognosis compared to other triple negative tumors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2019.12.012DOI Listing

Detailed overview on rare malignant ovarian tumors.

Bull Cancer 2020 Mar 27;107(3):385-390. Epub 2020 Feb 27.

Department of Medical Oncology, centre Léon-Bérard, University Claude Bernard (UCBL Lyon1), Lyon, France. Electronic address:

The group of rare malignant ovarian tumors includes the group of germ cell tumors, sex cords stromal ovarian tumors, small cell carcinoma, malignant Brenner tumors, rare epithelial tumors such as mucinous carcinoma, clear cell carcinoma, or low-grade serous carcinoma, as well as ovarian carcinosarcoma. Together they comprise about 10% of all ovarian tumors. Due to their low prevalence and their heterogeneity, data and treatment recommendations are limited. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.01.011DOI Listing

[When epitranscriptomics meets the ribosome: A new avenue in oncology].

Bull Cancer 2020 03 27;107(3):292-293. Epub 2020 Feb 27.

Centre de Recherche en Cancérologie de Lyon UMR Inserm 1052 - CNRS 5286 - UCBL-CLB, 28, rue Laennec, 69008 Lyon, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.02.001DOI Listing

[Preoperative breast imaging review: Interests and limits of specialized validation in oncology].

Bull Cancer 2020 Mar 27;107(3):295-307. Epub 2020 Feb 27.

Centre Antoine-Lacassagne, service de chirurgie oncologique gynécologique et sénologique, 33, avenue Valombrose, 06189 Nice, France.

Objectives: To evaluate the impact of systematic radiological review by breast specialist radiologist of malignant breast lesion imaging on the therapeutic management of patients.

Materials And Methods: Data collection was performed for patients with histopathologically proved breast cancer or suspicious breast lesion on imaging realized out of our institution. Patients underwent systematic mammary and axillary ultrasound, imaging review and if necessary complementary mammographic images. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2019.11.013DOI Listing

[Radiochemotherapy of HPV-positive oropharyngeal carcinomas: Cisplatin is still to be prioritized].

Bull Cancer 2020 03 26;107(3):293-294. Epub 2020 Feb 26.

Institut de Cancérologie de l'Ouest, 44805 Nantes St-Herblain Cedex, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.02.002DOI Listing

[Lung cancer screening: Nelson study is finally published].

Bull Cancer 2020 Feb;107(2):143-144

AP-HP. Centre - Université de Paris, Hôpital Cochin, Unité d'Oncologie Thoracique, Service de Pneumologie, 75014 Paris, France; Centre de Recherche des Cordeliers, Université de Paris, UMRS 1138 «Complement, Inflammation and Cancer», 75006 Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2020.02.003DOI Listing
February 2020

[Current advances in immunotherapy in ovarian cancer].

Bull Cancer 2020 Apr 20;107(4):465-473. Epub 2020 Feb 20.

Centre Léon-Bérard, 28, rue Laennec, 69008 Lyon, France.

Ovarian cancers express highly immunogenic tissue-specific antigens. The resulting immune infiltration is a major prognostic factor. There is therefore a strong biological rationale for the development of immunotherapy in ovarian cancer. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2019.11.015DOI Listing

[NTRK Fusions: A new way of treatment for gastro-intestinal tumor?]

Bull Cancer 2020 Apr 14;107(4):447-457. Epub 2020 Feb 14.

AP-HP, hôpital Saint-Antoine, service d'oncologie médicale, 75012 Paris, France; Sorbonne université, Paris, France. Electronic address:

The advent of molecular biology resulted in the discovery of new oncogenes that have led to the development of targeted therapies for the management of cancer patients. The development of these therapies has improved the prognosis of patients in various tumour localizations. The TRK receptor (tropomyosin receptor kinase) is a transmembrane receptor with a tyrosine kinase activity that plays a role in both cell proliferation and the physiology of the nervous system. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bulcan.2019.11.014DOI Listing
April 2020
0.635 Impact Factor