771 results match your criteria Building Services Engineering Research & Technology[Journal]


In and Beyond COVID-19: US Academic Pharmaceutical Science and Engineering Community Must Engage to Meet Critical National Needs.

AAPS PharmSciTech 2020 May 24;21(5):153. Epub 2020 May 24.

The National Institute for Pharmaceutical Technology and Education (NIPTE), Inc., Minneapolis, Minnesota, 55414, USA.

The supply of affordable, high-quality pharmaceuticals to US patients has been on a critical path for decades. In and beyond the COVID-19 pandemic, this critical path has become tortuous. To regain reliability, reshoring of the pharmaceutical supply chain to the USA is now a vital national security need. Read More

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http://dx.doi.org/10.1208/s12249-020-01718-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245992PMC

The Indoor Chemical Human Emissions and Reactivity project (ICHEAR): Overview of experimental methodology and preliminary results.

Indoor Air 2020 May 18. Epub 2020 May 18.

Max Planck Institute for Chemistry, Mainz, Germany.

With the gradual reduction of emissions from building products, emissions from human occupants become more dominant indoors. The impact of human emissions on indoor air quality is inadequately understood. The aim of the Indoor Chemical Human Emissions and Reactivity (ICHEAR) project was to examine the impact on indoor air chemistry of whole-body, exhaled and dermally emitted human bioeffluents under different conditions comprising human factors (t-shirts/shorts vs. Read More

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http://dx.doi.org/10.1111/ina.12687DOI Listing

Education and Training to Build Capacity in Total Worker Health®: Proposed Competencies for an Emerging Field.

J Occup Environ Med 2020 May 12. Epub 2020 May 12.

Center for Health, Work & Environment, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus (Newman); Department of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus (Newman, Scott, Tenney); Department of Epidemiology, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus (Newman, Scott, Tenney); Department of Medicine, University of Colorado, Anschutz Medical Campus (Newman); 2U, Inc (Scott); Office of the Director, Office for Total Worker Health, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention (Childress, Newhall); University of North Carolina Gillings School of Global Public Health (Linnan, Rogers); Center for Community-Based Research, Dana-Farber Cancer Institute (McLellan); Center for Work, Health, and Well-Being, Harvard T.H. Chan School of Public Health (McLellan); Healthier Workforce Center of the Midwest, College of Public Health, University of Iowa (Campo, Rohlman); Department of Community and Behavioral Health, College of Public Health, University of Iowa (Campo); Safe and Healthy Workplace Center, SAIF (Freewynn); Oregon Healthy Workplace Center, Oregon Health & Science University (Hammer); Carolina Collaborative for Research on Work and Health (Leff); Center for Environmental and Workplace Health, Department of Public Health, College of Health & Human Services, Western Kentucky University (Watkins); Office of the Director, Office of Extramural Program, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention (Maples); North Carolina Occupational Safety and Health and Education and Research Center (Rogers); Department of Environmental Sciences and Engineering, University of North Carolina (Rogers); Department of Occupational and Environmental Health, College of Public Health, University of Iowa (Rohlman).

Objective: Establishment of core competencies for education and training of professionals entering the emerging field of Total Worker Health®.

Methods: Compilation and distillation of information obtained over a five-year period from Total Worker Health symposia, workshops, and academic offerings, plus contributions from key stakeholders regarding education and training needs.

Results: A proposed set of Total Worker Health competencies aligns under six broad domains: Subject Matter Expertise; Advocacy and Engagement; Program Planning, Implementation and Evaluation; Communications and Dissemination; Leadership and Management; and Partnership Building and Coordination. Read More

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http://dx.doi.org/10.1097/JOM.0000000000001906DOI Listing

[Several considerations on the establishment of a new public health and preventive medicine system in national level].

Zhonghua Yu Fang Yi Xue Za Zhi 2020 May;54(5):469-474

Public Health College of Harbin Medical University, Harbin 150081, China.

Based on the new mission of public health set in the Healthy China strategy and the insufficient response to COVID-19, this article pointed out the problems of the current public health and preventive medicine system from the macro-system level, meso-organization level, and micro-individual level, including insufficient strategic planning, resource input, institutional coordination, talent training and team building. It was creatively proposed that a disease prevention and control bureau should be set up outside the health commission to implement the vertical management at four levels, from national level to province-level, including autonomous region, municipality directly under the central government, city-level and district/county-level. The disease prevention and control bureau should consist of a strategic research institute, a center for disease prevention and control (CDC), a human resources training base, and a scientific research institute, which could perform their own duties and rely on each other. Read More

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http://dx.doi.org/10.3760/cma.j.cn112150-20200221-00159DOI Listing

Contrasting Photo-Switching Rates in Azobenzene Derivatives: How the Nature of the Substituent Plays a Role.

Polymers (Basel) 2020 Apr 30;12(5). Epub 2020 Apr 30.

Department of Chemical Engineering (DEQ), Rovira i Virgili University, Av. Països Catalans 26, 43007 Tarragona, Spain.

A molecular design approach was used to create asymmetrical visible light-triggered azo-derivatives that can be good candidates for polymer functionalization. The specific electron-donor substituted molecules were characterized and studied by means of NMR analyses and UV-visible spectroscopy, comparing the results with Time Dependent Density Functional (TD-DFT) calculations. A slow rate of isomerization (k = 1. Read More

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http://dx.doi.org/10.3390/polym12051019DOI Listing
April 2020
2.505 Impact Factor

Emergency Supply Policy of Cryopreserved RBC and PLT: The Czech Republic Concept.

Transfus Apher Sci 2020 Apr 19:102788. Epub 2020 Apr 19.

International Consultancy in Strategic Safety Improvements of Blood-Derived Bioproducts and Suppliers Quality Audit / Inspection, London, United Kingdom. Electronic address:

Supply of blood for urgent substitution is a strategic logistical problem for the military medical services across the world. The limited shelf life of blood- derived bioproductsin the liquid state and the need for special transport and use conditions, apart from donor and donations availability are among the causes for concern. To solve these problems many national health-care authorities implemented the national emergency blood crisis policy, to get a large amount of blood at any time at any place in the case of disaster, terrorist attack or war. Read More

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http://dx.doi.org/10.1016/j.transci.2020.102788DOI Listing

Local conditions and policy design determine whether ecological compensation can achieve No Net Loss goals.

Nat Commun 2020 Apr 29;11(1):2072. Epub 2020 Apr 29.

Centre for Biodiversity and Conservation Science, The University of Queensland, St Lucia, QLD, 4072, Australia.

Many nations use ecological compensation policies to address negative impacts of development projects and achieve No Net Loss (NNL) of biodiversity and ecosystem services. Yet, failures are widely reported. We use spatial simulation models to quantify potential net impacts of alternative compensation policies on biodiversity (indicated by native vegetation) and two ecosystem services (carbon storage, sediment retention) across four case studies (in Australia, Brazil, Indonesia, Mozambique). Read More

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http://dx.doi.org/10.1038/s41467-020-15861-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190705PMC

Can rain suppress smoldering peat fire?

Sci Total Environ 2020 Apr 15;727:138468. Epub 2020 Apr 15.

Research Centre for Fire Engineering, Department of Building Services Engineering, The Hong Kong Polytechnic University, Kowloon, Hong Kong. Electronic address:

Smoldering wildfire in peatlands contributes significantly to global carbon emissions and regional haze events. Smoldering fire in peatlands is one of the largest and most persistent fire phenomena on Earth. Here we assess the underlying mechanism of rain in suppressing the smoldering peat fire in the shallow soil layer up to 15 cm deep through laboratory experiments. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.138468DOI Listing

Hallux valgus severity, great toe pain, and plantar pressures during gait: A cross-sectional study of community-dwelling adults.

Musculoskeletal Care 2020 Apr 20. Epub 2020 Apr 20.

Primary Care Centre Versus Arthritis, School of Primary, Community and Social Care, Keele University, Keele, Staffordshire, UK.

Background: Hallux valgus (HV) is a common disabling condition affecting 36% of adults aged 65 years and over. Identifying whether the severity of the deformity alters weight-bearing patterns during walking may assist clinicians optimize offloading interventions. Therefore, we examined how plantar pressure distributions during walking are affected by HV severity. Read More

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http://dx.doi.org/10.1002/msc.1472DOI Listing

A survey on the BWM Convention: analysing the stakeholders' perceptions with emphasis on the acquisition process and operational expenditure.

Environ Sci Pollut Res Int 2020 Apr 20. Epub 2020 Apr 20.

Department of Maritime Transportation and Management Engineering, Istanbul Technical University (ITU), İstanbul, Turkey.

The International Convention for the Control and Management of Ships' Ballast Water and Sediments (IMO 2018 Edition) was adopted in 2004 and entered into force on 8 September 2017, aiming to introduce global regulations to control the transfer of potentially invasive species Resolution (IMO MEPC.207(62) 2011). These efforts are translated into a wide range of solutions for retrofitting and new building services, which is evidenced through the substantial amount of data disclosed and analysed by different parties showing that optimization processes will have an important role for the existent management systems. Read More

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http://dx.doi.org/10.1007/s11356-020-08722-3DOI Listing

Demand for community-based care services and its influencing factors among the elderly in affordable housing communities: a case study in Nanjing City.

BMC Health Serv Res 2020 Mar 23;20(1):241. Epub 2020 Mar 23.

School of Civil Engineering, Southeast University, Jiangning District, Nanjing, 211189, China.

Background: Community-based care services refers to the professional services provided at home to the elderly with formally assessed demands. The growth of the elderly population has increased the demand for these services, and this issue is even worse in the affordable housing community (AHC) of China. Understanding of elderly's demands for different types of community-based care services and its determinations would enable the implementation of appropriate incentive schemes to promote utilization of community-based care services in the AHCs of China. Read More

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http://dx.doi.org/10.1186/s12913-020-5067-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092588PMC

Consumption of Diet Soda Sweetened with Sucralose and Acesulfame-Potassium Alters Inflammatory Transcriptome Pathways in Females with Overweight and Obesity.

Mol Nutr Food Res 2020 Apr 13:e1901166. Epub 2020 Apr 13.

Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, The George Washington University, 950 New Hampshire Avenue NW, Washington, DC, 20052, USA.

Scope: Low-calorie sweetener (LCS) consumption is associated with metabolic disease in observational studies. However, physiologic mechanisms underlying LCS-induced metabolic impairments in humans are unclear. This study is aimed at identifying molecular pathways in adipose impacted by LCSs. Read More

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http://dx.doi.org/10.1002/mnfr.201901166DOI Listing

Re-engineering the Cypriot healthcare service system.

BMC Health Serv Res 2020 Apr 7;20(1):293. Epub 2020 Apr 7.

School of Population Health and Environmental Sciences, King's College London, London, UK.

Background: The Cypriot healthcare system has undergone a number of major transformations since the induction of the Republic of Cyprus in the European Union over 10 years ago. Currently Cyprus is undergoing a major reform, namely the introduction of a primary care driven national healthcare system. The aim of the study was to assess the existing state of training, support, quality, guidelines and infrastructure towards a better healthcare system in Cyprus. Read More

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http://dx.doi.org/10.1186/s12913-020-5048-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137859PMC

Building visualization skills through investigating the coauthorship network from 2006-2017.

J Med Libr Assoc 2020 Apr 1;108(2):229-241. Epub 2020 Apr 1.

University Librarian, OHSU Library, Oregon Health & Science University, Portland, OR, http://orcid.org/0000-0002-4521-3523.

Objective: The primary objective of this study was to explore different dimensions of authorship from 2006-2017. Dimensions that were evaluated using coauthorship networks and affiliation data included collaboration, geographical reach, and relationship between Medical Library Association (MLA) member and nonmember authors. A secondary objective was to analyze the practice and practical application of data science skills. Read More

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http://dx.doi.org/10.5195/jmla.2020.775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069816PMC

ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries.

Authors:
Paul M Thompson Neda Jahanshad Christopher R K Ching Lauren E Salminen Sophia I Thomopoulos Joanna Bright Bernhard T Baune Sara Bertolín Janita Bralten Willem B Bruin Robin Bülow Jian Chen Yann Chye Udo Dannlowski Carolien G F de Kovel Gary Donohoe Lisa T Eyler Stephen V Faraone Pauline Favre Courtney A Filippi Thomas Frodl Daniel Garijo Yolanda Gil Hans J Grabe Katrina L Grasby Tomas Hajek Laura K M Han Sean N Hatton Kevin Hilbert Tiffany C Ho Laurena Holleran Georg Homuth Norbert Hosten Josselin Houenou Iliyan Ivanov Tianye Jia Sinead Kelly Marieke Klein Jun Soo Kwon Max A Laansma Jeanne Leerssen Ulrike Lueken Abraham Nunes Joseph O' Neill Nils Opel Fabrizio Piras Federica Piras Merel C Postema Elena Pozzi Natalia Shatokhina Carles Soriano-Mas Gianfranco Spalletta Daqiang Sun Alexander Teumer Amanda K Tilot Leonardo Tozzi Celia van der Merwe Eus J W Van Someren Guido A van Wingen Henry Völzke Esther Walton Lei Wang Anderson M Winkler Katharina Wittfeld Margaret J Wright Je-Yeon Yun Guohao Zhang Yanli Zhang-James Bhim M Adhikari Ingrid Agartz Moji Aghajani André Aleman Robert R Althoff Andre Altmann Ole A Andreassen David A Baron Brenda L Bartnik-Olson Janna Marie Bas-Hoogendam Arielle R Baskin-Sommers Carrie E Bearden Laura A Berner Premika S W Boedhoe Rachel M Brouwer Jan K Buitelaar Karen Caeyenberghs Charlotte A M Cecil Ronald A Cohen James H Cole Patricia J Conrod Stephane A De Brito Sonja M C de Zwarte Emily L Dennis Sylvane Desrivieres Danai Dima Stefan Ehrlich Carrie Esopenko Graeme Fairchild Simon E Fisher Jean-Paul Fouche Clyde Francks Sophia Frangou Barbara Franke Hugh P Garavan David C Glahn Nynke A Groenewold Tiril P Gurholt Boris A Gutman Tim Hahn Ian H Harding Dennis Hernaus Derrek P Hibar Frank G Hillary Martine Hoogman Hilleke E Hulshoff Pol Maria Jalbrzikowski George A Karkashadze Eduard T Klapwijk Rebecca C Knickmeyer Peter Kochunov Inga K Koerte Xiang-Zhen Kong Sook-Lei Liew Alexander P Lin Mark W Logue Eileen Luders Fabio Macciardi Scott Mackey Andrew R Mayer Carrie R McDonald Agnes B McMahon Sarah E Medland Gemma Modinos Rajendra A Morey Sven C Mueller Pratik Mukherjee Leyla Namazova-Baranova Talia M Nir Alexander Olsen Peristera Paschou Daniel S Pine Fabrizio Pizzagalli Miguel E Rentería Jonathan D Rohrer Philipp G Sämann Lianne Schmaal Gunter Schumann Mark S Shiroishi Sanjay M Sisodiya Dirk J A Smit Ida E Sønderby Dan J Stein Jason L Stein Masoud Tahmasian David F Tate Jessica A Turner Odile A van den Heuvel Nic J A van der Wee Ysbrand D van der Werf Theo G M van Erp Neeltje E M van Haren Daan van Rooij Laura S van Velzen Ilya M Veer Dick J Veltman Julio E Villalon-Reina Henrik Walter Christopher D Whelan Elisabeth A Wilde Mojtaba Zarei Vladimir Zelman

Transl Psychiatry 2020 Mar 20;10(1):100. Epub 2020 Mar 20.

Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across 43 countries, studying the human brain in health and disease. Building on large-scale genetic studies that discovered the first robustly replicated genetic loci associated with brain metrics, ENIGMA has diversified into over 50 working groups (WGs), pooling worldwide data and expertise to answer fundamental questions in neuroscience, psychiatry, neurology, and genetics. Most ENIGMA WGs focus on specific psychiatric and neurological conditions, other WGs study normal variation due to sex and gender differences, or development and aging; still other WGs develop methodological pipelines and tools to facilitate harmonized analyses of "big data" (i. Read More

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http://dx.doi.org/10.1038/s41398-020-0705-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083923PMC
March 2020
4.360 Impact Factor

Physical fitness training for stroke patients.

Cochrane Database Syst Rev 2020 03 20;3:CD003316. Epub 2020 Mar 20.

University of Edinburgh, Centre for Clinical Brain Sciences, Room S1642, Royal Infirmary, Little France Crescent, Edinburgh, UK, EH16 4SA.

Background: Levels of physical activity and physical fitness are low after stroke. Interventions to increase physical fitness could reduce mortality and reduce disability through increased function.

Objectives: The primary objectives of this updated review were to determine whether fitness training after stroke reduces death, death or dependence, and disability. Read More

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http://dx.doi.org/10.1002/14651858.CD003316.pub7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083515PMC

Environmental assessment of domestic water supply options for remote communities.

Water Res 2020 May 10;175:115687. Epub 2020 Mar 10.

Sustainable Industrial Systems, Department of Chemical Engineering and Analytical Science, The University of Manchester, The Mill, Sackville Street, Manchester, M13 9PL, UK. Electronic address:

Access to clean water is one of the targets in the UN Sustainable Development Goals. However, millions of people are still without basic water services, predominantly in rural areas in developing nations. Previous studies have investigated the environmental impacts of water provision, but they mostly focused on large-scale urban systems. Read More

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http://dx.doi.org/10.1016/j.watres.2020.115687DOI Listing

Estimating Urban Road GPS Environment Friendliness with Bus Trajectories: A City-Scale Approach .

Sensors (Basel) 2020 Mar 12;20(6). Epub 2020 Mar 12.

School of Computing and Communications, Lancaster University, Lancaster LA1 4YW, UK.

GPS is taken as the most prevalent positioning system in practice. However, in urban areas, as the GPS satellite signal could be blocked by buildings, the GPS positioning is not accurate due to multi-path errors. Estimating the negative impact of urban environments on GPS accuracy, that is the GPS environment friendliness (GEF) in this paper, will help to predict the GPS errors in different road segments. Read More

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http://dx.doi.org/10.3390/s20061580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146484PMC

APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice.

Sci Rep 2020 Mar 9;10(1):4277. Epub 2020 Mar 9.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, 630 West 168th Street, New York, NY, 10032, USA.

The ε4 allele of apolipoprotein E (APOE) is the dominant genetic risk factor for late-onset Alzheimer's disease (AD). However, the reason for the association between APOE4 and AD remains unclear. While much of the research has focused on the ability of the apoE4 protein to increase the aggregation and decrease the clearance of Aβ, there is also an abundance of data showing that APOE4 negatively impacts many additional processes in the brain, including bioenergetics. Read More

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http://dx.doi.org/10.1038/s41598-020-61142-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062695PMC

Two-Dimensional Perovskite Oxynitride K LaTa O N with an H /K Exchangeability in Aqueous Solution Forming a Stable Photocatalyst for Visible-Light H Evolution.

Angew Chem Int Ed Engl 2020 Mar 5. Epub 2020 Mar 5.

Department of Chemistry, School of Science, Tokyo Institute of Technology, 2-12-1-NE-2 Ookayama, Meguro-ku, Tokyo, 152-8550, Japan.

Undoped layered oxynitrides have not been considered as promising H -evolution photocatalysts because of the low chemical stability of oxynitrides in aqueous solution. Here, we demonstrate the synthesis of a new layered perovskite oxynitride, K LaTa O N, as an exceptional example of a water-tolerant photocatalyst for H evolution under visible light. The material underwent in-situ H /K exchange in aqueous solution while keeping its visible-light-absorption capability. Read More

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http://dx.doi.org/10.1002/anie.202002534DOI Listing

Simple and affordable imaging of multiple physiological parameters with RGB camera-based diffuse reflectance spectroscopy.

Biomed Opt Express 2020 Feb 24;11(2):1073-1091. Epub 2020 Jan 24.

Yamagata University, Graduate School of Bio-System Engineering, Jonan, Yonezawa-shi, Yamagata, 992-8510, Japan.

We propose a simple and affordable imaging technique to evaluate transcutaneously multiple physiological parameters by using a digital red-green-blue camera. In this method, the -values were converted into tristimulus values in the CIE (Commission Internationale de l'Eclairage) XYZ color space, which is compatible with the common color spaces. Monte Carlo simulation for light transport in biological tissue was then performed to specify the relationship among the -values and the concentrations of oxygenated hemoglobin, deoxygenated hemoglobin, bilirubin, and melanin. Read More

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http://dx.doi.org/10.1364/BOE.382270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041446PMC
February 2020

Imaging of intratumoral heterogeneity in high-grade glioma.

Cancer Lett 2020 May 27;477:97-106. Epub 2020 Feb 27.

Mathematical NeuroOncology Lab, Precision Neurotherapeutics Innovation Program, Mayo Clinic, 5777 East Mayo Blvd, Support, Services Building Suite 2-700, Phoenix, AZ, 85054, USA. Electronic address:

High-grade glioma (HGG), and particularly Glioblastoma (GBM), can exhibit pronounced intratumoral heterogeneity that confounds clinical diagnosis and management. While conventional contrast-enhanced MRI lacks the capability to resolve this heterogeneity, advanced MRI techniques and PET imaging offer a spectrum of physiologic and biophysical image features to improve the specificity of imaging diagnoses. Published studies have shown how integrating these advanced techniques can help better define histologically distinct targets for surgical and radiation treatment planning, and help evaluate the regional heterogeneity of tumor recurrence and response assessment following standard adjuvant therapy. Read More

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http://dx.doi.org/10.1016/j.canlet.2020.02.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108976PMC

Pre-screening the intrinsic angiogenic capacity of biomaterials in an optimised chorioallantoic membrane model.

J Tissue Eng 2020 Jan-Dec;11:2041731420901621. Epub 2020 Feb 4.

Regenerative Biomaterials Group, RAFT Institute, Mount Vernon Hospital, Northwood, UK.

Biomaterial development for clinical applications is currently on the rise. This necessitates adequate testing, where the structure and composition of biomaterials must be specifically tailored to withstand repair and regeneration responses for a successful clinical outcome. The chorioallantoic membrane of chicken embryos has been previously used to study angiogenesis, a prerequisite for most tissue repair and regeneration. Read More

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http://dx.doi.org/10.1177/2041731420901621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000866PMC
February 2020

Waste-to-Carbon: Is the Torrefied Sewage Sludge with High Ash Content a Better Fuel or Fertilizer?

Materials (Basel) 2020 Feb 20;13(4). Epub 2020 Feb 20.

Institute of Agricultural Engineering, Faculty of Life Sciences and Technology, Wroclaw University of Environmental and Life Sciences, 37a Chełmońskiego Str., 51-630 Wroclaw, Poland.

Sewage sludge (SS) recycling is an important part of the proposed 'circular economy' concept. SS can be valorized via torrefaction (also known as 'low-temperature pyrolysis' or 'roasting'). SS can, therefore, be considered a low-quality fuel or a source of nutrients essential for plant growth. Read More

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http://dx.doi.org/10.3390/ma13040954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078712PMC
February 2020

Towards a European health research and innovation cloud (HRIC).

Genome Med 2020 02 19;12(1):18. Epub 2020 Feb 19.

Department of Computer Science and Academic Computing Center Cyfronet, Akademia Gornizco Hutnizca University of Science and Technology, Krakow, Poland.

The European Union (EU) initiative on the Digital Transformation of Health and Care (Digicare) aims to provide the conditions necessary for building a secure, flexible, and decentralized digital health infrastructure. Creating a European Health Research and Innovation Cloud (HRIC) within this environment should enable data sharing and analysis for health research across the EU, in compliance with data protection legislation while preserving the full trust of the participants. Such a HRIC should learn from and build on existing data infrastructures, integrate best practices, and focus on the concrete needs of the community in terms of technologies, governance, management, regulation, and ethics requirements. Read More

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http://dx.doi.org/10.1186/s13073-020-0713-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029532PMC
February 2020

Freshwater mussels (Bivalvia: Unionidae) from the rising sun (Far East Asia): phylogeny, systematics, and distribution.

Mol Phylogenet Evol 2020 May 3;146:106755. Epub 2020 Feb 3.

CIIMAR/CIMAR - Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N, P 4450-208 Matosinhos, Portugal.

Freshwater mussels (Bivalvia: Unionidae) is a diverse family with around 700 species being widespread in the Northern Hemisphere and Africa. These animals fulfill key ecological functions and provide important services to humans. Unfortunately, populations have declined dramatically over the last century, rendering Unionidae one of the world's most imperiled taxonomic groups. Read More

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http://dx.doi.org/10.1016/j.ympev.2020.106755DOI Listing

Interdisciplinary Approach to Building Functionality for Weather Hazards.

Risk Anal 2020 Jan 28. Epub 2020 Jan 28.

Department of Civil and Environmental Engineering, University of Washington, Seattle, WA, USA.

It is estimated that in the United States, people spend 90% of their time in buildings. In order to ensure quality of life for communities, we propose a human-centric design approach to building "functionality." "Functionality" is defined as the set of "essential services" to meet occupant needs for safety and well-being. Read More

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http://dx.doi.org/10.1111/risa.13450DOI Listing
January 2020

User-provider experiences of the implementation of KidzAlive-driven child-friendly spaces in KwaZulu-Natal, South Africa.

BMC Public Health 2020 Jan 21;20(1):91. Epub 2020 Jan 21.

Department of Public Health Medicine, University of KwaZulu-Natal, George Campbell Building, Room 217, 2nd Floor, King George V Avenue, Glenwood, Durban, KwaZulu-Natal, 4041, South Africa.

Background: KidzAlive is a child-centred intervention aimed at improving the quality of HIV care for children in South Africa. Through this intervention, 10 child-friendly spaces were created in 10 primary healthcare centres (PHCs) in KwaZulu-Natal to enhance child-centred HIV care. However, the user-provider experiences of these child-friendly spaces in these facilities have not been explored. Read More

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http://dx.doi.org/10.1186/s12889-019-7712-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975036PMC
January 2020

Automatic Indoor as-Built Building Information Models Generation by Using Low-Cost RGB-D Sensors.

Sensors (Basel) 2020 Jan 4;20(1). Epub 2020 Jan 4.

Shenzhen Research Institute, The Hong Kong Polytechnic University, Shenzhen 518057, China.

To generate indoor as-built building information models (AB BIMs) automatically and economically is a great technological challenge. Many approaches have been developed to address this problem in recent years, but it is far from being settled, particularly for the point cloud segmentation and the extraction of the relationship among different elements due to the complicated indoor environment. This is even more difficult for the low-quality point cloud generated by low-cost scanning equipment. Read More

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http://dx.doi.org/10.3390/s20010293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983176PMC
January 2020

MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer.

Br J Cancer 2020 Mar 16;122(6):868-884. Epub 2020 Jan 16.

The Wistar Institute, Molecular and Cellular Oncogenesis, 3601 Spruce Street, Philadelphia, PA, 19104, USA.

Background: Recent studies have suggested that fatty acid oxidation (FAO) is a key metabolic pathway for the growth of triple negative breast cancers (TNBCs), particularly those that have high expression of MYC. However, the underlying mechanism by which MYC promotes FAO remains poorly understood.

Methods: We used a combination of metabolomics, transcriptomics, bioinformatics, and microscopy to elucidate a potential mechanism by which MYC regulates FAO in TNBC. Read More

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http://dx.doi.org/10.1038/s41416-019-0711-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078291PMC

Technical Note: A digital reference object representing Hoffman's 3D brain phantom for PET scanner simulations.

Med Phys 2020 Mar 5;47(3):1174-1180. Epub 2020 Feb 5.

Department of Radiology, University of Washington Medical Center, Box 357987, Seattle, WA, 98195-7987, USA.

Purpose: Physical and digital phantoms play a key role in the development and testing of nuclear medicine instrumentation and processing algorithms for clinical and research applications, including neuroimaging using positron emission tomography (PET). We have developed and tested a digital reference object (DRO) version of the original segmented magnetic resonance imaging (MRI) data used for the three-dimensional (3D) PET brain phantom developed by Hoffman et al., which is used as the basis of a commercially available physical test phantom. Read More

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http://dx.doi.org/10.1002/mp.14012DOI Listing

Publisher Correction: The Scales Project, a cross-national dataset on the interpretation of thermal perception scales.

Authors:
Marcel Schweiker Amar Abdul-Zahra Maíra André Farah Al-Atrash Hanan Al-Khatri Rea Risky Alprianti Hayder Alsaad Rucha Amin Eleni Ampatzi Alpha Yacob Arsano Montazami Azadeh Elie Azar Bannazadeh Bahareh Amina Batagarawa Susanne Becker Carolina Buonocore Bin Cao Joon-Ho Choi Chungyoon Chun Hein Daanen Siti Aisyah Damiati Lyrian Daniel Renata De Vecchi Shivraj Dhaka Samuel Domínguez-Amarillo Edyta Dudkiewicz Lakshmi Prabha Edappilly Jesica Fernández-Agüera Mireille Folkerts Arjan Frijns Gabriel Gaona Vishal Garg Stephanie Gauthier Shahla Ghaffari Jabbari Djamila Harimi Runa T Hellwig Gesche M Huebner Quan Jin Mina Jowkar Renate Kania Jungsoo Kim Nelson King Boris Kingma M Donny Koerniawan Jakub Kolarik Shailendra Kumar Alison Kwok Roberto Lamberts Marta Laska M C Jeffrey Lee Yoonhee Lee Vanessa Lindermayr Mohammadbagher Mahaki Udochukwu Marcel-Okafor Laura Marín-Restrepo Anna Marquardsen Francesco Martellotta Jyotirmay Mathur Gráinne McGill Isabel Mino-Rodriguez Di Mou Bassam Moujalled Mia Nakajima Edward Ng Marcellinus Okafor Mark Olweny Wanlu Ouyang Ana Ligia Papst de Abreu Alexis Pérez-Fargallo Indrika Rajapaksha Greici Ramos Saif Rashid Christoph F Reinhart Ma Isabel Rivera Mazyar Salmanzadeh Karin Schakib-Ekbatan Stefano Schiavon Salman Shooshtarian Masanori Shukuya Veronica Soebarto Suhendri Mohammad Tahsildoost Federico Tartarini Despoina Teli Priyam Tewari Samar Thapa Maureen Trebilcock Jörg Trojan Ruqayyatu B Tukur Conrad Voelker Yeung Yam Liu Yang Gabriela Zapata-Lancaster Yongchao Zhai Yingxin Zhu Zahra Sadat Zomorodian

Sci Data 2020 01 6;7(1):11. Epub 2020 Jan 6.

Department of construction, Shahid Beheshti University, Evin, 1983969411, Tehran, Iran.

An amendment to this paper has been published and can be accessed via a link at the top of the paper. Read More

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http://dx.doi.org/10.1038/s41597-019-0348-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944681PMC
January 2020

Integrating embedded resources and network analysis to understand food-energy-water nexus in the US.

Sci Total Environ 2020 Mar 17;709:136153. Epub 2019 Dec 17.

Department of Civil and Environmental Engineering, The Pennsylvania State University, University Park, PA, United States of America; Rock Ethics Institute, The Pennsylvania State University, University Park, PA, United States of America. Electronic address:

To find a sustainable way of supplying food, energy, and water (FEW) while simultaneously protecting the ecosystem services, it is imperative to build greater understanding on interconnections, feedback, and dependencies in FEW systems. The FEW nexus has developed as a field of study to provide frameworks for such pursuits. Building upon previous work in this paper, we analyze FEW resources through the development of a virtual water trade network using the US network of food and energy flows and their associated virtual water contents. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.136153DOI Listing

The Scottish national LifeCurve™ survey: costs of functional decline, opportunities to achieve early intervention to support well-being in later life, and meaningfulness of the LifeCurve™.

Public Health 2020 Mar 27;180:129-135. Epub 2019 Dec 27.

Newcastle University Institute for Ageing, 2nd Floor Biomedical Research Building, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK. Electronic address:

Objectives: The aim of the Scottish AHP LifeCurve™ survey was to gather a snapshot of where people are on their LifeCurve™ when receiving allied health professions (AHP) services and to understand the cost consequence of intervening 'late' in the ageing trajectory. The objectives were to promote discussion around preventing functional decline, support innovation in service delivery, and facilitate broader engagement with individuals, communities, and wider environments for improving health and well-being in later life. In addition, subsequent learning could help address the increasing resource gap between the demand and capacity across health and social care. Read More

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http://dx.doi.org/10.1016/j.puhe.2019.10.014DOI Listing

Philosophy of Science Series: Harnessing the Multidisciplinary Edge Effect by Exploring Paradigms, Ontologies, Epistemologies, Axiologies, and Methodologies.

Acad Med 2020 May;95(5):686-689

L. Varpio is professor and associate director of research, Graduate Programs in Health Professions Education, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland; ORCID: https://orcid.org/0000-0002-1412-4341. A. MacLeod is professor of continuing professional development and medical education, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

Health professions education (HPE) researchers come from many different academic traditions, from psychology to engineering to rhetoric. Trained in these traditions, HPE researchers engage in science and the building of new knowledge from different paradigmatic orientations. Collaborating across these traditions is particularly generative, a phenomenon the authors call the multidisciplinary edge effect. Read More

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http://dx.doi.org/10.1097/ACM.0000000000003142DOI Listing

A prospective compound screening contest identified broader inhibitors for Sirtuin 1.

Sci Rep 2019 12 20;9(1):19585. Epub 2019 Dec 20.

Education Academy of Computational Life Sciences (ACLS), Tokyo Institute of Technology, 4259 Nagatsutacho, Midori-ku, Yokohama, 226-8501, Japan.

Potential inhibitors of a target biomolecule, NAD-dependent deacetylase Sirtuin 1, were identified by a contest-based approach, in which participants were asked to propose a prioritized list of 400 compounds from a designated compound library containing 2.5 million compounds using in silico methods and scoring. Our aim was to identify target enzyme inhibitors and to benchmark computer-aided drug discovery methods under the same experimental conditions. Read More

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http://dx.doi.org/10.1038/s41598-019-55069-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925144PMC
December 2019
5.078 Impact Factor

Sustainment, Sustainability, and Spread Study (SSaSSy): protocol for a study of factors that contribute to the sustainment, sustainability, and spread of practice changes introduced through an evidence-based quality-improvement intervention in Canadian nursing homes.

Implement Sci 2019 12 19;14(1):109. Epub 2019 Dec 19.

Faculty of Nursing, University of Alberta, 5-183, Edmonton Clinic Health Academy, 11405 87 Ave, Edmonton, Alberta, T6G 1C9, Canada.

Background: Implementation scientists and practitioners, alike, recognize the importance of sustaining practice change, however post-implementation studies of interventions are rare. This is a protocol for the Sustainment, Sustainability and Spread Study (SSaSSy). The purpose of this study is to contribute to knowledge on the sustainment (sustained use), sustainability (sustained benefits), and spread of evidence-based practice innovations in health care. Read More

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http://dx.doi.org/10.1186/s13012-019-0959-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923960PMC
December 2019

Profiling the effect of nafcillin on HA-MRSA D712 using bacteriological and physiological media.

Sci Data 2019 12 17;6(1):322. Epub 2019 Dec 17.

Division of Biological Sciences, University of California San Diego, La Jolla, CA, 92093, USA.

Staphylococcus aureus strains have been continuously evolving resistance to numerous classes of antibiotics including methicillin, vancomycin, daptomycin and linezolid, compounding the enormous healthcare and economic burden of the pathogen. Cation-adjusted Mueller-Hinton broth (CA-MHB) is the standard bacteriological media for measuring antibiotic susceptibility in the clinical lab, but the use of media that more closely mimic the physiological state of the patient, e.g. Read More

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http://dx.doi.org/10.1038/s41597-019-0331-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917727PMC
December 2019

Promoting healthy teenage behaviour across three European countries through the use of a novel smartphone technology platform, PEGASO fit for future: study protocol of a quasi-experimental, controlled, multi-Centre trial.

BMC Med Inform Decis Mak 2019 12 17;19(1):278. Epub 2019 Dec 17.

Agency for Health Quality and Assessment of Catalonia (AQuAS), Catalan Department of Health, Roc Boronat 81-95, 2nd floor, 08005, Barcelona, Spain.

Background: Behaviour change interventions targeting physical activity, diet, sleep and sedentary behaviour of teenagers show promise when delivered through smartphones. However, to date there is no evidence of effectiveness of multicomponent smartphone-based interventions. Utilising a user-centred design approach, we developed a theory-based, multi-dimensional system, PEGASO Fit For Future (PEGASO F4F), which exploits sophisticated game mechanics involving smartphone applications, a smartphone game and activity sensors to motivate teenagers to take an active role in adopting and maintaining a healthy lifestyle. Read More

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http://dx.doi.org/10.1186/s12911-019-0958-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918671PMC
December 2019

Accompanimeter 1.0: creation and initial field testing of a tool to assess the extent to which the principles and building blocks of accompaniment are present in community health worker programs.

Glob Health Action 2019 ;12(1):1699348

Community Health Systems, Partners In Health, Boston, MA, USA.

: The strategic incorporation of community health workers (CHWs) into health system strengthening efforts is recognized as a critical and high-value approach for meeting the Sustainable Development Goals established by the United Nations in 2015. How to best build CHW programs, however, is prone to a wide variety of opinions and philosophies, many of which are often externally imposed. Partners in Health (PIH) is a non-governmental organization that pioneered an approach to healthcare system strengthening, called accompaniment, in which CHWs play a key role. Read More

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http://dx.doi.org/10.1080/16549716.2019.1699348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913655PMC

Assessment of Antitumor Potential and Combination Effect of Classical and Molecular-targeted Anticancer Drugs.

Anticancer Res 2019 Dec;39(12):6673-6684

Meikai University Research Institute of Odontology (M-RIO), Sakado, Japan

Background/aim: The aim of the study was to evaluate the antitumor potential and combination effects of chemotherapeutic drugs.

Materials And Methods: The cytotoxicity of 20 drip-type classical and molecular-targeted anticancer drugs was examined against 4 human oral squamous cell carcinoma cell lines and 5 human oral normal mesenchymal and epithelial cells. Cell cycle progression was monitored by a cell sorter. Read More

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http://dx.doi.org/10.21873/anticanres.13882DOI Listing
December 2019

The emotional labour of quality improvement work in end of life care: a qualitative study of Patient and Family Centred Care (PFCC) in England.

BMC Health Serv Res 2019 Dec 2;19(1):923. Epub 2019 Dec 2.

Centre for Health and Social Care, St George's, University of London and Kingston University, CHSCR, 6th Floor, Hunter wing, London, SW17 0QT, UK.

Background: There is a growing emphasis on understanding patient experience in order to inform efforts to support improvement. This paper reports findings from an implementation study of an evidence-based intervention called Patient and Family Centred Care (PFCC) designed to tap into patient experiences as a basis for improvement. In this study the PFCC intervention was spread to a new service area (end of life care) and delivered at scale in England. Read More

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http://dx.doi.org/10.1186/s12913-019-4762-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889450PMC
December 2019

Congenital Heart Disease in Low- and Lower-Middle-Income Countries: Current Status and New Opportunities.

Curr Cardiol Rep 2019 11 29;21(12):163. Epub 2019 Nov 29.

Western Cape Paediatric Cardiology Services, Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital and University of Cape Town, 2.17 Institute of Child Health Building, Klipfontein Rd Mowbray, 7700, South Africa.

Purpose Of Review: The paper summarises the most recent data on congenital heart disease (CHD) in low- and lower-middle-income countries (LLMICs). In addition, we present an approach to diagnosis, management and interventions in these regions and present innovations, research priorities and opportunities to improve outcomes and develop new programs.

Recent Findings: The reported birth prevalence of CHD in LLMICs is increasing, with clear evidence of the impact of surgical intervention on the burden of disease. Read More

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http://dx.doi.org/10.1007/s11886-019-1248-zDOI Listing
November 2019

Exercise and Progressive Supranuclear Palsy: the need for explicit exercise reporting.

BMC Neurol 2019 Nov 29;19(1):305. Epub 2019 Nov 29.

La Trobe Centre for Sport and Exercise Medicine Research, School Allied Health, Human Services and Sport, College Science, Health & Engineering, La Trobe University, Kingsbury Drive, Bundoora, 3086, Australia.

Background: Progressive Supranuclear Palsy (PSP) is the most frequent form of atypical Parkinsonism. Although there is preliminary evidence for the benefits of gait rehabilitation, balance training and oculomotor exercises in PSP, the quality of reporting of exercise therapies appears mixed. The current investigation aims to evaluate the comprehensiveness of reporting of exercise and physical activity interventions in the PSP literature. Read More

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http://dx.doi.org/10.1186/s12883-019-1539-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884751PMC
November 2019

The Scales Project, a cross-national dataset on the interpretation of thermal perception scales.

Authors:
Marcel Schweiker Amar Abdul-Zahra Maíra André Farah Al-Atrash Hanan Al-Khatri Rea Risky Alprianti Hayder Alsaad Rucha Amin Eleni Ampatzi Alpha Yacob Arsano Montazami Azadeh Elie Azar Bannazadeh Bahareh Amina Batagarawa Susanne Becker Carolina Buonocore Bin Cao Joon-Ho Choi Chungyoon Chun Hein Daanen Siti Aisyah Damiati Lyrian Daniel Renata De Vecchi Shivraj Dhaka Samuel Domínguez-Amarillo Edyta Dudkiewicz Lakshmi Prabha Edappilly Jesica Fernández-Agüera Mireille Folkerts Arjan Frijns Gabriel Gaona Vishal Garg Stephanie Gauthier Shahla Ghaffari Jabbari Djamila Harimi Runa T Hellwig Gesche M Huebner Quan Jin Mina Jowkar Renate Kania Jungsoo Kim Nelson King Boris Kingma M Donny Koerniawan Jakub Kolarik Shailendra Kumar Alison Kwok Roberto Lamberts Marta Laska M C Jeffrey Lee Yoonhee Lee Vanessa Lindermayr Mohammadbagher Mahaki Udochukwu Marcel-Okafor Laura Marín-Restrepo Anna Marquardsen Francesco Martellotta Jyotirmay Mathur Gráinne McGill Isabel Mino-Rodriguez Di Mou Bassam Moujalled Mia Nakajima Edward Ng Marcellinus Okafor Mark Olweny Wanlu Ouyang Ana Ligia Papst de Abreu Alexis Pérez-Fargallo Indrika Rajapaksha Greici Ramos Saif Rashid Christoph F Reinhart Ma Isabel Rivera Mazyar Salmanzadeh Karin Schakib-Ekbatan Stefano Schiavon Salman Shooshtarian Masanori Shukuya Veronica Soebarto Suhendri Mohammad Tahsildoost Federico Tartarini Despoina Teli Priyam Tewari Samar Thapa Maureen Trebilcock Jörg Trojan Ruqayyatu B Tukur Conrad Voelker Yeung Yam Liu Yang Gabriela Zapata-Lancaster Yongchao Zhai Yingxin Zhu Zahra Sadat Zomorodian

Sci Data 2019 11 26;6(1):289. Epub 2019 Nov 26.

Department of construction, Shahid Beheshti University, Evin, 1983969411, Tehran, Iran.

Thermal discomfort is one of the main triggers for occupants' interactions with components of the built environment such as adjustments of thermostats and/or opening windows and strongly related to the energy use in buildings. Understanding causes for thermal (dis-)comfort is crucial for design and operation of any type of building. The assessment of human thermal perception through rating scales, for example in post-occupancy studies, has been applied for several decades; however, long-existing assumptions related to these rating scales had been questioned by several researchers. Read More

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http://dx.doi.org/10.1038/s41597-019-0272-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879730PMC
November 2019

Workers' compensation claims for traumatic brain injuries among private employers-Ohio, 2001-2011.

Am J Ind Med 2020 02 19;63(2):156-169. Epub 2019 Nov 19.

Division of Safety and Hygiene, Ohio Bureau of Workers' Compensation, Pickerington, Ohio.

Background: The purpose of this analysis was to identify and prioritize high-risk industry groups for traumatic brain injury (TBI) prevention efforts.

Methods: Workers with TBI from 2001 to 2011 were identified from the Ohio Bureau of Workers' Compensation data. To prioritize industry groups by claim type (lost-time (≥8 days away from work) and total claims) and injury event categories, we used a prevention index (PI) that averaged TBI counts and rate ranks (PI = (count rank + rate rank)/2). Read More

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http://dx.doi.org/10.1002/ajim.23073DOI Listing
February 2020

Impact of Hurricanes Irma and Maria on Puerto Rico Maternal and Child Health Research Programs.

Matern Child Health J 2020 Jan;24(1):22-29

Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Health Science Campus, 101 Buck Road, Athens, GA, 30602, USA.

Puerto Rico was hit by two major hurricanes in September 2017 causing great devastation, losing over 90% of the power grid, wireless communication and access to potable water, and destroying many homes. Our research programs: Puerto Rico Testsite for Exploring Contamination Threats (PROTECT), Center for Research on Early Childhood Exposure and Development in Puerto Rico (CRECE), Zika in Infants and Pregnancy (ZIP), and Environmental Influences on Child Health Outcomes (ECHO) are ongoing observational cohort studies that have been investigating environmental risk factors for perinatal health outcomes among Puerto Rican mothers and infants. Our projects paused operations for about two weeks, to begin recovery process and become a source of assistance, retaining 95% of study participants across all research programs. Read More

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http://dx.doi.org/10.1007/s10995-019-02824-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059554PMC
January 2020

The :p.Arg658* truncating variant is associated with risk of triple-negative breast cancer.

Authors:
Gisella Figlioli Massimo Bogliolo Irene Catucci Laura Caleca Sandra Viz Lasheras Roser Pujol Johanna I Kiiski Taru A Muranen Daniel R Barnes Joe Dennis Kyriaki Michailidou Manjeet K Bolla Goska Leslie Cora M Aalfs Muriel A Adank Julian Adlard Simona Agata Karen Cadoo Bjarni A Agnarsson Thomas Ahearn Kristiina Aittomäki Christine B Ambrosone Lesley Andrews Hoda Anton-Culver Natalia N Antonenkova Volker Arndt Norbert Arnold Kristan J Aronson Banu K Arun Ella Asseryanis Bernd Auber Päivi Auvinen Jacopo Azzollini Judith Balmaña Rosa B Barkardottir Daniel Barrowdale Julian Barwell Laura E Beane Freeman Charles Joly Beauparlant Matthias W Beckmann Sabine Behrens Javier Benitez Raanan Berger Marina Bermisheva Amie M Blanco Carl Blomqvist Natalia V Bogdanova Anders Bojesen Stig E Bojesen Bernardo Bonanni Ake Borg Angela F Brady Hiltrud Brauch Hermann Brenner Thomas Brüning Barbara Burwinkel Saundra S Buys Trinidad Caldés Almuth Caliebe Maria A Caligo Daniele Campa Ian G Campbell Federico Canzian Jose E Castelao Jenny Chang-Claude Stephen J Chanock Kathleen B M Claes Christine L Clarke Anita Collavoli Thomas A Conner David G Cox Cezary Cybulski Kamila Czene Mary B Daly Miguel de la Hoya Peter Devilee Orland Diez Yuan Chun Ding Gillian S Dite Nina Ditsch Susan M Domchek Cecilia M Dorfling Isabel Dos-Santos-Silva Katarzyna Durda Miriam Dwek Diana M Eccles Arif B Ekici A Heather Eliassen Carolina Ellberg Mikael Eriksson D Gareth Evans Peter A Fasching Jonine Figueroa Henrik Flyger William D Foulkes Tara M Friebel Eitan Friedman Marike Gabrielson Pragna Gaddam Manuela Gago-Dominguez Chi Gao Susan M Gapstur Judy Garber Montserrat García-Closas José A García-Sáenz Mia M Gaudet Simon A Gayther Graham G Giles Gord Glendon Andrew K Godwin Mark S Goldberg David E Goldgar Pascal Guénel Angelica M Gutierrez-Barrera Lothar Haeberle Christopher A Haiman Niclas Håkansson Per Hall Ute Hamann Patricia A Harrington Alexander Hein Jane Heyworth Peter Hillemanns Antoinette Hollestelle John L Hopper H Dean Hosgood Anthony Howell Chunling Hu Peter J Hulick David J Hunter Evgeny N Imyanitov Claudine Isaacs Milena Jakimovska Anna Jakubowska Paul James Ramunas Janavicius Wolfgang Janni Esther M John Michael E Jones Audrey Jung Rudolf Kaaks Beth Y Karlan Elza Khusnutdinova Cari M Kitahara Irene Konstantopoulou Stella Koutros Peter Kraft Diether Lambrechts Conxi Lazaro Loic Le Marchand Jenny Lester Fabienne Lesueur Jenna Lilyquist Jennifer T Loud Karen H Lu Robert N Luben Jan Lubinski Arto Mannermaa Mehdi Manoochehri Siranoush Manoukian Sara Margolin John W M Martens Tabea Maurer Dimitrios Mavroudis Noura Mebirouk Alfons Meindl Usha Menon Austin Miller Marco Montagna Katherine L Nathanson Susan L Neuhausen William G Newman Tu Nguyen-Dumont Finn Cilius Nielsen Sarah Nielsen Liene Nikitina-Zake Kenneth Offit Edith Olah Olufunmilayo I Olopade Andrew F Olshan Janet E Olson Håkan Olsson Ana Osorio Laura Ottini Bernard Peissel Ana Peixoto Julian Peto Dijana Plaseska-Karanfilska Timea Pocza Nadege Presneau Miquel Angel Pujana Kevin Punie Brigitte Rack Johanna Rantala Muhammad U Rashid Rohini Rau-Murthy Gad Rennert Flavio Lejbkowicz Valerie Rhenius Atocha Romero Matti A Rookus Eric A Ross Maria Rossing Vilius Rudaitis Matthias Ruebner Emmanouil Saloustros Kristin Sanden Marta Santamariña Maren T Scheuner Rita K Schmutzler Michael Schneider Christopher Scott Leigha Senter Mitul Shah Priyanka Sharma Xiao-Ou Shu Jacques Simard Christian F Singer Christof Sohn Penny Soucy Melissa C Southey John J Spinelli Linda Steele Dominique Stoppa-Lyonnet William J Tapper Manuel R Teixeira Mary Beth Terry Mads Thomassen Jennifer Thompson Darcy L Thull Marc Tischkowitz Rob A E M Tollenaar Diana Torres Melissa A Troester Thérèse Truong Nadine Tung Michael Untch Celine M Vachon Elizabeth J van Rensburg Elke M van Veen Ana Vega Alessandra Viel Barbara Wappenschmidt Jeffrey N Weitzel Camilla Wendt Greet Wieme Alicja Wolk Xiaohong R Yang Wei Zheng Argyrios Ziogas Kristin K Zorn Alison M Dunning Michael Lush Qin Wang Lesley McGuffog Michael T Parsons Paul D P Pharoah Florentia Fostira Amanda E Toland Irene L Andrulis Susan J Ramus Anthony J Swerdlow Mark H Greene Wendy K Chung Roger L Milne Georgia Chenevix-Trench Thilo Dörk Marjanka K Schmidt Douglas F Easton Paolo Radice Eric Hahnen Antonis C Antoniou Fergus J Couch Heli Nevanlinna Jordi Surrallés Paolo Peterlongo

NPJ Breast Cancer 2019 1;5:38. Epub 2019 Nov 1.

IFOM - the FIRC Institute for Molecular Oncology, Genome Diagnostics Program, Milan, Italy.

Breast cancer is a common disease partially caused by genetic risk factors. Germline pathogenic variants in DNA repair genes , , , , and are associated with breast cancer risk. , which encodes for a DNA translocase, has been proposed as a breast cancer predisposition gene, with greater effects for the ER-negative and triple-negative breast cancer (TNBC) subtypes. Read More

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http://dx.doi.org/10.1038/s41523-019-0127-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825205PMC
November 2019
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Human Health and Ecosystem Impacts of Deep Decarbonization of the Energy System.

Environ Sci Technol 2019 Dec 15;53(23):14054-14062. Epub 2019 Nov 15.

Interdisciplinary Research Laboratory on Sustainable Engineering and Ecodesign (LIRIDE), Civil and Building Engineering Department , Université de Sherbrooke , 2500 boul. de l'Université , Sherbrooke J1K 2R1 , Québec , Canada.

Global warming mitigation strategies are likely to affect human health and biodiversity through diverse cause-effect mechanisms. To analyze these effects, we implement a methodology to link TIMES energy models with life cycle assessment using open-source software. The proposed method uses a cutoff to identify the most relevant processes. Read More

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http://dx.doi.org/10.1021/acs.est.9b04923DOI Listing
December 2019