606 results match your criteria Building Services Engineering Research & Technology[Journal]


Analysis of tractable allosteric sites in G protein-coupled receptors.

Sci Rep 2019 Apr 16;9(1):6180. Epub 2019 Apr 16.

Medicinal Chemistry Research Group, Research Center for Natural Sciences, Magyar tudósok krt. 2, H-1117, Budapest, Hungary.

Allosteric modulation of G protein-coupled receptors represent a promising mechanism of pharmacological intervention. Dramatic developments witnessed in the structural biology of membrane proteins continue to reveal that the binding sites of allosteric modulators are widely distributed, including along protein surfaces. Here we restrict consideration to intrahelical and intracellular sites together with allosteric conformational locks, and show that the protein mapping tools FTMap and FTSite identify 83% and 88% of such experimentally confirmed allosteric sites within the three strongest sites found. Read More

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http://dx.doi.org/10.1038/s41598-019-42618-8DOI Listing

Longitudinal assessment of the association between implementation strategy use and the uptake of hepatitis C treatment: Year 2.

Implement Sci 2019 Apr 8;14(1):36. Epub 2019 Apr 8.

Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare System, University Drive, Pittsburgh, PA, USA.

Background: To increase the uptake of evidence-based treatments for hepatitis C (HCV), the Department of Veterans Affairs (VA) established the Hepatitis Innovation Team (HIT) Collaborative. Teams of providers were tasked with choosing implementation strategies to improve HCV care. The aim of the current evaluation was to assess how site-level implementation strategies were associated with HCV treatment initiation and how the use of implementation strategies and their association with HCV treatment changed over time. Read More

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http://dx.doi.org/10.1186/s13012-019-0881-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454775PMC

Try to see it my way: exploring the co-design of visual presentations of wellbeing through a workshop process.

Perspect Public Health 2019 Apr 8:1757913919835231. Epub 2019 Apr 8.

Institute of Health and Wellbeing, Administration Building, Gartnavel Royal Hospital, Glasgow, UK.

Aims:: A 10-month project funded by the NewMind network sought to develop the specification of a visualisation toolbox that could be applied on digital platforms (web- or app-based) to support adults with lived experience of mental health difficulties to present and track their personal wellbeing in a multi-media format.

Methods:: A participant co-design methodology, Double Diamond from the Design Council (Great Britain), was used consisting of four phases: Discover - a set of literature and app searches of wellbeing and health visualisation material; Define - an initial workshop with participants with lived experience of mental health problems to discuss wellbeing and visualisation techniques and to share personal visualisations; Develop - a second workshop to add detail to personal visualisations, for example, forms of media to be employed, degree of control over sharing; and Deliver - to disseminate the learning from the exercise.

Results:: Two design workshops were held in December 2017 and April 2018 with 13 and 12 experts-by-experience involved, respectively, including two peer researchers (co-authors) and two individual-carer dyads in each workshop, with over 50% of those being present in both workshops. Read More

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http://dx.doi.org/10.1177/1757913919835231DOI Listing

Distinct Profiles on Subjective and Objective Adherence Measures in Patients Prescribed Antidepressants.

Drugs 2019 Apr 3. Epub 2019 Apr 3.

Division of Pharmacoepidemiology and Clinical Pharmacology, Faculty of Science, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

Objective: A recurrent observation is that associations between self-reported and objective medication adherence measures are often weak to moderate. Our aim was therefore to identify patients with different profiles on self-reported and objective adherence measures.

Study Design And Setting: This was an observational study of 221 community pharmacy patients who were dispensed antidepressants. Read More

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http://dx.doi.org/10.1007/s40265-019-01107-yDOI Listing

Supporting implementation of Cochrane methods in complex communication reviews: resources developed and lessons learned for editorial practice and policy.

Health Res Policy Syst 2019 Mar 28;17(1):32. Epub 2019 Mar 28.

Cochrane Consumers and Communication Group, Centre for Health Communication and Participation, School of Psychology and Public Health, College of Science, Health and Engineering, La Trobe University, Victoria, 3086, Australia.

Every healthcare encounter involves some form of communication and there is growing recognition that effective health communication is central to the delivery of safe, high-quality healthcare. Conversely, poor communication has a range of adverse consequences for those receiving healthcare and the systems delivering care, including elevated patient safety risks. Increasing understanding and documentation of the key role that good communication plays in healthcare design and delivery has meant there is growing demand from policy-makers and other decision-makers for evidence on the effects of health communication interventions - that is, how best to communicate. Read More

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http://dx.doi.org/10.1186/s12961-019-0435-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437949PMC

Five simultaneous artificial intelligence data challenges on ultrasound, CT, and MRI.

Diagn Interv Imaging 2019 Apr 15;100(4):199-209. Epub 2019 Mar 15.

Lille Regional University Hospital, Musculoskeletal Imaging Department, 59000 Lille, France.

Purpose: The goal of this data challenge was to create a structured dynamic with the following objectives: (1) teach radiologists the new rules of General Data Protection Regulation (GDPR), while building a large multicentric prospective database of ultrasound, computed tomography (CT) and MRI patient images; (2) build a network including radiologists, researchers, start-ups, large companies, and students from engineering schools, and; (3) provide all French stakeholders working together during 5 data challenges with a secured framework, offering a realistic picture of the benefits and concerns in October 2018.

Materials And Methods: Relevant clinical questions were chosen by the Société Francaise de Radiologie. The challenge was designed to respect all French ethical and data protection constraints. Read More

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http://dx.doi.org/10.1016/j.diii.2019.02.001DOI Listing

SEIS: Insight's Seismic Experiment for Internal Structure of Mars.

Authors:
P Lognonné W B Banerdt D Giardini W T Pike U Christensen P Laudet S de Raucourt P Zweifel S Calcutt M Bierwirth K J Hurst F Ijpelaan J W Umland R Llorca-Cejudo S A Larson R F Garcia S Kedar B Knapmeyer-Endrun D Mimoun A Mocquet M P Panning R C Weber A Sylvestre-Baron G Pont N Verdier L Kerjean L J Facto V Gharakanian J E Feldman T L Hoffman D B Klein K Klein N P Onufer J Paredes-Garcia M P Petkov J R Willis S E Smrekar M Drilleau T Gabsi T Nebut O Robert S Tillier C Moreau M Parise G Aveni S Ben Charef Y Bennour T Camus P A Dandonneau C Desfoux B Lecomte O Pot P Revuz D Mance J tenPierick N E Bowles C Charalambous A K Delahunty J Hurley R Irshad Huafeng Liu A G Mukherjee I M Standley A E Stott J Temple T Warren M Eberhardt A Kramer W Kühne E-P Miettinen M Monecke C Aicardi M André J Baroukh A Borrien A Bouisset P Boutte K Brethomé C Brysbaert T Carlier M Deleuze J M Desmarres D Dilhan C Doucet D Faye N Faye-Refalo R Gonzalez C Imbert C Larigauderie E Locatelli L Luno J-R Meyer F Mialhe J M Mouret M Nonon Y Pahn A Paillet P Pasquier G Perez R Perez L Perrin B Pouilloux A Rosak I Savin de Larclause J Sicre M Sodki N Toulemont B Vella C Yana F Alibay O M Avalos M A Balzer P Bhandari E Blanco B D Bone J C Bousman P Bruneau F J Calef R J Calvet S A D'Agostino G de Los Santos R G Deen R W Denise J Ervin N W Ferraro H E Gengl F Grinblat D Hernandez M Hetzel M E Johnson L Khachikyan J Y Lin S M Madzunkov S L Marshall I G Mikellides E A Miller W Raff J E Singer C M Sunday J F Villalvazo M C Wallace D Banfield J A Rodriguez-Manfredi C T Russell A Trebi-Ollennu J N Maki E Beucler M Böse C Bonjour J L Berenguer S Ceylan J Clinton V Conejero I Daubar V Dehant P Delage F Euchner I Estève L Fayon L Ferraioli C L Johnson J Gagnepain-Beyneix M Golombek A Khan T Kawamura B Kenda P Labrot N Murdoch C Pardo C Perrin L Pou A Sauron D Savoie S Stähler E Stutzmann N A Teanby J Tromp M van Driel M Wieczorek R Widmer-Schnidrig J Wookey

Space Sci Rev 2019 28;215(1):12. Epub 2019 Jan 28.

27School of Earth Sciences, University of Bristol, Wills Memorial Building, Queens Road, Bristol, BS8 1RJ UK.

By the end of 2018, 42 years after the landing of the two Viking seismometers on Mars, InSight will deploy onto Mars' surface the SEIS (eismic xperiment for nternal tructure) instrument; a six-axes seismometer equipped with both a long-period three-axes Very Broad Band (VBB) instrument and a three-axes short-period (SP) instrument. These six sensors will cover a broad range of the seismic bandwidth, from 0.01 Hz to 50 Hz, with possible extension to longer periods. Read More

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http://dx.doi.org/10.1007/s11214-018-0574-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394762PMC
January 2019

The Living Environment and Thermal Behaviours of Older South Australians: A Multi-Focus Group Study.

Int J Environ Res Public Health 2019 Mar 15;16(6). Epub 2019 Mar 15.

School of Architecture and Built Environment, The University of Adelaide, North Terrace, Adelaide, SA 5005, Australia.

Ageing brings about physiological changes that affect people's thermal sensitivity and thermoregulation. The majority of older Australians prefer to age in place and modifications to the home environment are often required to accommodate the occupants as they age and possibly become frail. However, modifications to aid thermal comfort are not always considered. Read More

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https://www.mdpi.com/1660-4601/16/6/935
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http://dx.doi.org/10.3390/ijerph16060935DOI Listing
March 2019
2 Reads
2.063 Impact Factor

Evaluating the Risk of Epidemic Thunderstorm Asthma: Lessons from Australia.

Int J Environ Res Public Health 2019 Mar 7;16(5). Epub 2019 Mar 7.

Menzies Institute for Medical Research, University of Tasmania, 1 Liverpool St, Hobart, TAS 7000, Australia.

Epidemic thunderstorm asthma (ETA) is an emerging public health threat in Australia, highlighted by the 2016 event in Melbourne, Victoria, that overwhelmed health services and caused loss of life. However, there is limited understanding of the regional variations in risk. We evaluated the public health risk of ETA in the nearby state of Tasmania by quantifying the frequency of potential ETA episodes and applying a standardized natural disaster risk assessment framework. Read More

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http://dx.doi.org/10.3390/ijerph16050837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427665PMC
March 2019
11 Reads

From Discovery to Practice and Survivorship: Building a National Real-World Data Learning Healthcare Framework for Military and Veteran Cancer Patients.

Clin Pharmacol Ther 2019 Mar 5. Epub 2019 Mar 5.

John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and Walter Reed National Military Medical Center, Bethesda, MD.

The Applied Proteogenomics OrganizationaL Learning and Outcomes (APOLLO) network is implementing a prospective curation and translation of real-world data into real-world evidence within the learning healthcare environment of the Department of Defense and Department of Veterans Affairs. To support basic, translational, clinical, and epidemiological sciences, APOLLO will release data to public repositories for secondary analysis to assist others in assessing whether similar molecular-driven clinical practice guidelines will improve health outcomes for their relevant cancer populations. This article is protected by copyright. Read More

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http://doi.wiley.com/10.1002/cpt.1425
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http://dx.doi.org/10.1002/cpt.1425DOI Listing
March 2019
4 Reads

Urban ecology, stakeholders and the future of ecology.

Sci Total Environ 2019 Jun 27;667:475-484. Epub 2019 Feb 27.

Direction de l'environnement, Conseil Régional Hauts-de-France, 59019 Lille, France.

The world human population is more and more urban and cities have a strong impact on the biosphere. This explains the development of urban ecology. In this context, the goal of our work is fourfold: to describe the diversity of scientific questions in urban ecology, show how these questions are organized, to assess how these questions can be built in close interactions with stakeholders, to better understand the role urban ecology can play within ecological sciences. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.02.410DOI Listing
June 2019
2 Reads

Polar auxin transport is essential to maintain growth and development of etiolated pea and maize seedlings grown under 1 g conditions: Relevance to the international space station experiment.

Life Sci Space Res (Amst) 2019 Feb 15;20:1-11. Epub 2018 Nov 15.

Graduate School of Science, Osaka Prefecture University, 1-1 Gakuen-cho, Naka-ku, Sakai, Osaka 599-8531, Japan. Electronic address:

We conducted "Auxin Transport" space experiments in 2016 and 2017 in the Japanese Experiment Module (JEM) on the International Space Station (ISS), with the principal objective being integrated analyses of the growth and development of etiolated pea (Pisum sativum L. cv Alaska) and maize (Zea mays L. cv Golden Cross Bantam) seedlings under true microgravity conditions in space relative to auxin dynamics. Read More

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http://dx.doi.org/10.1016/j.lssr.2018.11.001DOI Listing
February 2019
1 Read

Physical activity-related health and economic benefits of building walkable neighbourhoods: a modelled comparison between brownfield and greenfield developments.

Int J Behav Nutr Phys Act 2019 Feb 20;16(1):11. Epub 2019 Feb 20.

RMIT University, Healthy Liveable Cities Group, Centre for Urban Research, Melbourne, Victoria, Australia.

Background: A consensus is emerging in the literature that urban form can impact health by either facilitating or deterring physical activity (PA). However, there is a lack of evidence measuring population health and the economic benefits relating to alternative urban forms. We examined the issue of housing people within two distinct types of urban development forms: a medium-density brownfield development in an established area with existing amenities (e. Read More

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http://dx.doi.org/10.1186/s12966-019-0775-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381620PMC
February 2019
1 Read

Stomatal Conductance Measurement for Toxicity Assessment in Zero-Effluent Constructed Wetlands: Effects of Landfill Leachate on Hydrophytes.

Int J Environ Res Public Health 2019 02 5;16(3). Epub 2019 Feb 5.

Department of Environmental Engineering, Faculty of Building Services, Hydro and Environmental Engineering, Warsaw University of Technology, 00-653 Warsaw, Poland.

In this research, we explore for the first time the use of leaf stomatal conductance (g) for phytotoxicity assessment. Plants respond to stress by regulating transpiration. Transpiration can be correlated with stomatal conductance when the water vapor pressure gradient for transpiration is constant. Read More

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http://dx.doi.org/10.3390/ijerph16030468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388108PMC
February 2019

Numerical evaluations of urban design technique to reduce vehicular personal intake fraction in deep street canyons.

Sci Total Environ 2019 Feb 28;653:968-994. Epub 2018 Oct 28.

School of Atmospheric Sciences, Guangdong Province Key Laboratory for Climate Change and Natural Disaster Studies, Sun Yat-sen University, Guangzhou, PR China. Electronic address:

High-rise deep street canyons usually experience poor ventilation and large vehicular pollutant exposure to residents in near-road buildings. Investigations are still required to clarify the flow and dispersion mechanisms in deep street canyons and explore techniques to reduce such large pollutant exposure. By conducting computational fluid dynamics (CFD) simulations validated by wind tunnel data and scale-model outdoor field measurements, we investigate the integrated impacts of aspect ratios, first-floor and second-floor elevated building designs, viaduct settings, height variations and wind catchers on the flow, personal intake fraction (P_IF) of CO (carbon dioxide) and its spatial mean value 〈P_IF〉 in two-dimensional (2D) street canyons. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2018.10.333DOI Listing
February 2019

Public health delivery in the information age: the role of informatics and technology.

Perspect Public Health 2019 Feb 13:1757913918802308. Epub 2019 Feb 13.

Department of Health Management and Informatics, School of Medicine, University of Missouri, Columbia, MO, USA.

Aim:: Public health systems have embraced health informatics and information technology as a potential transformational tool to improve real-time surveillance systems, communication, and sharing of information among various agencies. Global pandemic outbreaks like Zika and Ebola were quickly controlled due to electronic surveillance systems enabling efficient information access and exchange. However, there is the need for a more robust technology to enhance adequate epidemic forecasting, data sharing, and effective communication. Read More

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http://dx.doi.org/10.1177/1757913918802308DOI Listing
February 2019

CDDPath: A method for quantifying the loss and recovery of construction and demolition debris in the United States.

Waste Manag 2019 Feb 8;84:302-309. Epub 2018 Dec 8.

Innovative Waste Consulting Services, LLC, 6628 NW 9th Blvd., Suite 3, Gainesville, FL 32605, USA.

National generation estimates for seven material types in the construction and demolition debris stream are regularly published in the United States. However, the quantities of these materials in different end-of-life management pathways are not published or otherwise made available. Quantification of end-of-life management pathways is useful for identifying approaches to decrease disposal and increase material recovery. Read More

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http://dx.doi.org/10.1016/j.wasman.2018.11.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464109PMC
February 2019

Fast and Automatic Reconstruction of Semantically Rich 3D Indoor Maps from Low-quality RGB-D Sequences.

Sensors (Basel) 2019 Jan 27;19(3). Epub 2019 Jan 27.

Research Institute for Smart Cities & Shenzhen Key Laboratory of Spatial Information Smart Sensing and Services, School of Architecture and Urban Planning, Shenzhen University, Shenzhen 518060, China.

Semantically rich indoor models are increasingly used throughout a facility's life cycle for different applications. With the decreasing price of 3D sensors, it is convenient to acquire point cloud data from consumer-level scanners. However, most existing methods in 3D indoor reconstruction from point clouds involve a tedious manual or interactive process due to line-of-sight occlusions and complex space structures. Read More

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http://www.mdpi.com/1424-8220/19/3/533
Publisher Site
http://dx.doi.org/10.3390/s19030533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387083PMC
January 2019
11 Reads

Naturally-Derived Biphasic Calcium Phosphates through Increased Phosphorus-Based Reagent Amounts for Biomedical Applications.

Materials (Basel) 2019 Jan 25;12(3). Epub 2019 Jan 25.

Department of Metallic Materials Science, Physical Metallurgy, University Politehnica of Bucharest, 313 Splaiul Independentei, J Building, District 6, 060042 Bucharest, Romania.

Calcium carbonate from marble and seashells is an eco-friendly, sustainable, and largely available bioresource for producing natural bone-like calcium phosphates (CaPs). Based on three main objectives, this research targeted the: (i) adaptation of an indirect synthesis route by modulating the amount of phosphorus used in the chemical reaction, (ii) comprehensive structural, morphological, and surface characterization, and (iii) biocompatibility assessment of the synthesized powdered samples. The morphological characterization was performed on digitally processed scanning electron microscopy (SEM) images. Read More

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http://dx.doi.org/10.3390/ma12030381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384751PMC
January 2019

Shared heritability and functional enrichment across six solid cancers.

Authors:
Xia Jiang Hilary K Finucane Fredrick R Schumacher Stephanie L Schmit Jonathan P Tyrer Younghun Han Kyriaki Michailidou Corina Lesseur Karoline B Kuchenbaecker Joe Dennis David V Conti Graham Casey Mia M Gaudet Jeroen R Huyghe Demetrius Albanes Melinda C Aldrich Angeline S Andrew Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Natalia N Antonenkova Susanne M Arnold Kristan J Aronson Banu K Arun Elisa V Bandera Rosa B Barkardottir Daniel R Barnes Jyotsna Batra Matthias W Beckmann Javier Benitez Sara Benlloch Andrew Berchuck Sonja I Berndt Heike Bickeböller Stephanie A Bien Carl Blomqvist Stefania Boccia Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Hiltrud Brauch Hermann Brenner James D Brenton Mark N Brook Joan Brunet Hans Brunnström Daniel D Buchanan Barbara Burwinkel Ralf Butzow Gabriella Cadoni Trinidad Caldés Maria A Caligo Ian Campbell Peter T Campbell Géraldine Cancel-Tassin Lisa Cannon-Albright Daniele Campa Neil Caporaso André L Carvalho Andrew T Chan Jenny Chang-Claude Stephen J Chanock Chu Chen David C Christiani Kathleen B M Claes Frank Claessens Judith Clements J Margriet Collée Marcia Cruz Correa Fergus J Couch Angela Cox Julie M Cunningham Cezary Cybulski Kamila Czene Mary B Daly Anna deFazio Peter Devilee Orland Diez Manuela Gago-Dominguez Jenny L Donovan Thilo Dörk Eric J Duell Alison M Dunning Miriam Dwek Diana M Eccles Christopher K Edlund Digna R Velez Edwards Carolina Ellberg D Gareth Evans Peter A Fasching Robert L Ferris Triantafillos Liloglou Jane C Figueiredo Olivia Fletcher Renée T Fortner Florentia Fostira Silvia Franceschi Eitan Friedman Steven J Gallinger Patricia A Ganz Judy Garber José A García-Sáenz Simon A Gayther Graham G Giles Andrew K Godwin Mark S Goldberg David E Goldgar Ellen L Goode Marc T Goodman Gary Goodman Kjell Grankvist Mark H Greene Henrik Gronberg Jacek Gronwald Pascal Guénel Niclas Håkansson Per Hall Ute Hamann Freddie C Hamdy Robert J Hamilton Jochen Hampe Aage Haugen Florian Heitz Rolando Herrero Peter Hillemanns Michael Hoffmeister Estrid Høgdall Yun-Chul Hong John L Hopper Richard Houlston Peter J Hulick David J Hunter David G Huntsman Gregory Idos Evgeny N Imyanitov Sue Ann Ingles Claudine Isaacs Anna Jakubowska Paul James Mark A Jenkins Mattias Johansson Mikael Johansson Esther M John Amit D Joshi Radka Kaneva Beth Y Karlan Linda E Kelemen Tabea Kühl Kay-Tee Khaw Elza Khusnutdinova Adam S Kibel Lambertus A Kiemeney Jeri Kim Susanne K Kjaer Julia A Knight Manolis Kogevinas Zsofia Kote-Jarai Stella Koutros Vessela N Kristensen Jolanta Kupryjanczyk Martin Lacko Stephan Lam Diether Lambrechts Maria Teresa Landi Philip Lazarus Nhu D Le Eunjung Lee Flavio Lejbkowicz Heinz-Josef Lenz Goska Leslie Davor Lessel Jenny Lester Douglas A Levine Li Li Christopher I Li Annika Lindblom Noralane M Lindor Geoffrey Liu Fotios Loupakis Jan Lubiński Lovise Maehle Christiane Maier Arto Mannermaa Loic Le Marchand Sara Margolin Taymaa May Lesley McGuffog Alfons Meindl Pooja Middha Austin Miller Roger L Milne Robert J MacInnis Francesmary Modugno Marco Montagna Victor Moreno Kirsten B Moysich Lorelei Mucci Kenneth Muir Anna Marie Mulligan Katherine L Nathanson David E Neal Andrew R Ness Susan L Neuhausen Heli Nevanlinna Polly A Newcomb Lisa F Newcomb Finn Cilius Nielsen Liene Nikitina-Zake Børge G Nordestgaard Robert L Nussbaum Kenneth Offit Edith Olah Ali Amin Al Olama Olufunmilayo I Olopade Andrew F Olshan Håkan Olsson Ana Osorio Hardev Pandha Jong Y Park Nora Pashayan Michael T Parsons Tanja Pejovic Kathryn L Penney Wilbert H M Peters Catherine M Phelan Amanda I Phipps Dijana Plaseska-Karanfilska Miranda Pring Darya Prokofyeva Paolo Radice Kari Stefansson Susan J Ramus Leon Raskin Gad Rennert Hedy S Rennert Elizabeth J van Rensburg Marjorie J Riggan Harvey A Risch Angela Risch Monique J Roobol Barry S Rosenstein Mary Anne Rossing Kim De Ruyck Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Matthew B Schabath Johanna Schleutker Marjanka K Schmidt V Wendy Setiawan Hongbing Shen Erin M Siegel Weiva Sieh Christian F Singer Martha L Slattery Karina Dalsgaard Sorensen Melissa C Southey Amanda B Spurdle Janet L Stanford Victoria L Stevens Sebastian Stintzing Jennifer Stone Karin Sundfeldt Rebecca Sutphen Anthony J Swerdlow Eloiza H Tajara Catherine M Tangen Adonina Tardon Jack A Taylor M Dawn Teare Manuel R Teixeira Mary Beth Terry Kathryn L Terry Stephen N Thibodeau Mads Thomassen Line Bjørge Marc Tischkowitz Amanda E Toland Diana Torres Paul A Townsend Ruth C Travis Nadine Tung Shelley S Tworoger Cornelia M Ulrich Nawaid Usmani Celine M Vachon Els Van Nieuwenhuysen Ana Vega Miguel Elías Aguado-Barrera Qin Wang Penelope M Webb Clarice R Weinberg Stephanie Weinstein Mark C Weissler Jeffrey N Weitzel Catharine M L West Emily White Alice S Whittemore H-Erich Wichmann Fredrik Wiklund Robert Winqvist Alicja Wolk Penella Woll Michael Woods Anna H Wu Xifeng Wu Drakoulis Yannoukakos Wei Zheng Shanbeh Zienolddiny Argyrios Ziogas Kristin K Zorn Jacqueline M Lane Richa Saxena Duncan Thomas Rayjean J Hung Brenda Diergaarde James McKay Ulrike Peters Li Hsu Montserrat García-Closas Rosalind A Eeles Georgia Chenevix-Trench Paul J Brennan Christopher A Haiman Jacques Simard Douglas F Easton Stephen B Gruber Paul D P Pharoah Alkes L Price Bogdan Pasaniuc Christopher I Amos Peter Kraft Sara Lindström

Nat Commun 2019 01 25;10(1):431. Epub 2019 Jan 25.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.

Quantifying the genetic correlation between cancers can provide important insights into the mechanisms driving cancer etiology. Using genome-wide association study summary statistics across six cancer types based on a total of 296,215 cases and 301,319 controls of European ancestry, here we estimate the pair-wise genetic correlations between breast, colorectal, head/neck, lung, ovary and prostate cancer, and between cancers and 38 other diseases. We observed statistically significant genetic correlations between lung and head/neck cancer (r = 0. Read More

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http://dx.doi.org/10.1038/s41467-018-08054-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347624PMC
January 2019
13 Reads
10.742 Impact Factor

Attitudes to reform: Could a cooperative health insurance scheme work in Russia?

Int J Health Econ Manag 2019 Jan 22. Epub 2019 Jan 22.

Center for Fiscal Policy, Financial Research Institute of Ministry of Finance, Nastasyinsky Pereulok 3, Building 2, Office 101, Moscow, Russia, 127006.

As for all health systems, in Russia, the demand for medical care is greater than its health system is able to guarantee the supply of. In this context, removing services from the state guaranteed package is an option that is receiving serious consideration. In this paper, we examine the attitudes of the Russian population to such a reform. Read More

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http://dx.doi.org/10.1007/s10754-019-09260-3DOI Listing
January 2019
1 Read

Atrial mechanics and their prognostic impact in Takotsubo syndrome: a cardiovascular magnetic resonance imaging study.

Eur Heart J Cardiovasc Imaging 2019 Jan 10. Epub 2019 Jan 10.

Department of Cardiology and Pneumology, Georg-August University, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany.

Aims: The exact pathophysiology of Takotsubo syndrome (TTS) remains not fully understood with most studies focussing on ventricular pathology. Since atrial involvement may have a significant role, we assessed the diagnostic and prognostic potential of atrial cardiovascular magnetic resonance feature tracking (CMR-FT) in TTS.

Methods And Results: This multicentre study recruited 152 TTS patients who underwent CMR on average within 3 days after hospitalization. Read More

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http://dx.doi.org/10.1093/ehjci/jey219DOI Listing
January 2019
12 Reads

Monitoring of odors emitted from stabilized dewatered sludge subjected to aging using proton transfer reaction-mass spectrometry.

Environ Sci Pollut Res Int 2019 Feb 4;26(6):5500-5513. Epub 2019 Jan 4.

Faculty of Chemistry, Department of Analytical Chemistry, Gdańsk University of Technology, Narutowicza 11/12 Street, 80-233, Gdańsk, Poland.

One of the potential emission sources of odorous compounds from wastewater treatment plants is sludge processing. The odorous compounds released from dewatered sludge can result in odor nuisance. This study concerns the use of flux hood chamber combined with proton transfer reaction-time of flight-mass spectrometry (PTR-MS) technique for periodical monitoring of odorous compounds emitted from aged, stabilized dewatered sludge samples from 2 different wastewater treatment plants located in Pomeranian Voivodeship, Poland. Read More

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http://link.springer.com/10.1007/s11356-018-4041-4
Publisher Site
http://dx.doi.org/10.1007/s11356-018-4041-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403207PMC
February 2019
13 Reads

Single-cell redox states analyzed by fluorescence lifetime metrics and tryptophan FRET interaction with NAD(P)H.

Cytometry A 2019 Jan 2;95(1):110-121. Epub 2019 Jan 2.

The W.M. Keck Center for Cellular Imaging, Physical and Life Sciences Building (PLSB), University of Virginia, 90 Geldard Drive, Charlottesville, Virginia, 22904.

Redox changes in live HeLa cervical cancer cells after doxorubicin treatment can either be analyzed by a novel fluorescence lifetime microscopy (FLIM)-based redox ratio NAD(P)H-a2%/FAD-a1%, called fluorescence lifetime redox ratio or one of its components (NAD(P)H-a2%), which is actually driving that ratio and offering a simpler and alternative metric and are both compared. Auto-fluorescent NAD(P)H, FAD lifetime is acquired by 2- photon excitation and Tryptophan by 3-photon, at 4 time points after treatment up to 60 min demonstrating early drug response to doxorubicin. Identical Fields-of-view (FoV) at each interval allows single-cell analysis, showing heterogeneous responses to treatment, largely based on their initial control redox state. Read More

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http://doi.wiley.com/10.1002/cyto.a.23711
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http://dx.doi.org/10.1002/cyto.a.23711DOI Listing
January 2019
8 Reads

Exposing the impact of intensive advice services on health: A realist evaluation.

Health Soc Care Community 2019 May 17;27(3):767-776. Epub 2018 Dec 17.

Department of Social Work, Education and Community Wellbeing, Northumbria University, Benton, Newcastle Upon Tyne, UK.

Attention has turned to welfare advice as a potential health and social care intervention. However, establishing direct evidence of health impact has proven difficult. This is compounded by the need to understand both the facilitative contexts and mechanisms through which this impact occurs. Read More

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http://dx.doi.org/10.1111/hsc.12695DOI Listing

A comparative performance analysis of a renowned public private partnership for health care provision in Spain between 2003 and 2015.

Health Policy 2019 Apr 27;123(4):412-418. Epub 2018 Nov 27.

Health Services and Policy Research Group, Institute for Health Sciences in Aragón, IACS, Aragon, Spain; REDISSEC-Research Network for Health Services on Chronic Patients, Avda. San Juan Bosco 13 (CIBA Building), 50009, Zaragoza, Spain. Electronic address:

Background: Recently, the once archetype of the public private partnership (PPP) in the Spanish National Health System (SNHS), namely the Alzira's Model, has come to an end. Advocates defended the superiority of PPPs over public-tenured provision, in terms of quality and technical efficiency. This paper profiles and compares Alzira's life-cycle performance with similar public-tenured providers. Read More

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http://dx.doi.org/10.1016/j.healthpol.2018.11.009DOI Listing
April 2019
8 Reads

Identity Management Systems for the Internet of Things: A Survey Towards Blockchain Solutions.

Sensors (Basel) 2018 Dec 1;18(12). Epub 2018 Dec 1.

Big Data Lab, Engineering Division, The Pennsylvania State University, Malvern, PA 19355, USA.

The Internet of Things aims at connecting everything, ranging from individuals, organizations, and companies to things in the physical and virtual world. The digital identity has always been considered as the keystone for all online services and the foundation for building security mechanisms such as authentication and authorization. However, the current literature still lacks a comprehensive study on the digital identity management for the Internet of Things (IoT). Read More

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http://dx.doi.org/10.3390/s18124215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308926PMC
December 2018

The morphology and metabolic potential of the Chloroflexi in full-scale activated sludge wastewater treatment plants.

FEMS Microbiol Ecol 2019 Feb;95(2)

Department of Chemistry and Bioscience, Center for Microbial Communities, Aalborg University, Fredrik Bajers Vej 7H, DK-9220, Aalborg, Denmark.

Filamentous bacteria belonging to the phylum Chloroflexi have received considerable attention in wastewater treatment systems for their suggested role in the operational problem of impaired sludge settleability known as bulking. Their consistently high abundance in full-scale systems, even in the absence of bulking, indicates that they make a substantial contribution to the nutrient transformations during wastewater treatment. In this study, extensive 16S rRNA amplicon surveys of Danish wastewater treatment plants (WWTPs) with nutrient removal were screened to identify numerically important Chloroflexi genera. Read More

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https://academic.oup.com/femsec/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/femsec/fiy228DOI Listing
February 2019
22 Reads

Impact of societal factors and health care delivery systems on gastroschisis outcomes.

Semin Pediatr Surg 2018 Oct 28;27(5):316-320. Epub 2018 Aug 28.

Department of Surgery, Division of Pediatric Surgery, Lucile Packard Children's Hospital, Stanford University School of Medicine, 300 Pasteur Drive, Alway Building M116, Stanford, CA 94305, USA. Electronic address:

Care of infants with gastroschisis is associated with a significant burden on health care delivery systems. Mortality rates in patients with gastroschisis have significantly improved over the past few decades. However, the condition is still associated with significant short-term and potentially long-term morbidity. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10558586183007
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http://dx.doi.org/10.1053/j.sempedsurg.2018.08.010DOI Listing
October 2018
9 Reads

Translational Research Grants Scheme (TRGS): a new approach to strengthening health system research capacity.

Public Health Res Pract 2018 Sep 27;28(3). Epub 2018 Sep 27.

Office for Health and Medical Research, NSW Ministry of Health, Sydney, Australia.

Background: Bridging the 'gap' between research evidence and the complexities of policy and practice is central to health improvement. The Translational Research Grants Scheme (TRGS) in New South Wales (NSW), Australia, is a funding scheme aimed at reducing the time between research generation and translation to policy and practice. The TRGS is also an important part of NSW Health's efforts to harness and strengthen research capacity to improve health service delivery. Read More

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http://www.phrp.com.au/?p=37716
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http://dx.doi.org/10.17061/phrp2831818DOI Listing
September 2018
12 Reads

Setting research priorities to achieve long-term health targets in Iran.

J Glob Health 2018 Dec;8(2):020702

Engineering Seismology Department, International Institute of Earthquake Engineering and Seismology (IIEES), Tehran, Iran.

Background: In 2015, it was estimated that the burden of disease in Iran comprised of 19 million disability-adjusted life years (DALYs), 74% of which were due to non-communicable diseases (NCDs). The observed leading causes of death were cardiovascular diseases (41.9%), neoplasms (14. Read More

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http://jogh.org/documents/issue201802/jogh-08-020702.pdf
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http://dx.doi.org/10.7189/jogh.08.020702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188089PMC
December 2018
41 Reads

Soil and water bioengineering: Practice and research needs for reconciling natural hazard control and ecological restoration.

Sci Total Environ 2019 Jan 18;648:1210-1218. Epub 2018 Aug 18.

INRA, AMAP, CNRS, IRD, University Montpellier, CIRAD, Montpellier, France. Electronic address:

Soil and water bioengineering is a technology that encourages scientists and practitioners to combine their knowledge and skills in the management of ecosystems with a common goal to maximize benefits to both man and the natural environment. It involves techniques that use plants as living building materials, for: (i) natural hazard control (e.g. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00489697183318
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http://dx.doi.org/10.1016/j.scitotenv.2018.08.217DOI Listing
January 2019
3 Reads

A discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy.

Nat Commun 2018 10 18;9(1):4335. Epub 2018 Oct 18.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, 20892, USA.

Photodynamic therapy is an effective alternative to traditional treatments due to its minimally invasive nature, negligible systemic toxicity, fewer side effects, and avoidance of drug resistance. However, it is still challenging to design photosensitizers with high singlet oxygen (O) quantum yields (QY) due to severe aggregation of the hydrophobic photosensitizers. Herein, we developed a discrete organoplatinum(II) metallacage using therapeutic cis-(PEt)Pt(OTf) as the building block to improve the O QY, thus achieving synergistic anticancer efficacy. Read More

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http://www.nature.com/articles/s41467-018-06574-7
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http://dx.doi.org/10.1038/s41467-018-06574-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194061PMC
October 2018
28 Reads

Functional, impulse-based quantification of plantar pressure patterns in typical adult gait.

Gait Posture 2019 01 1;67:122-127. Epub 2018 Oct 1.

Glenrose Rehabilitation Hospital, Alberta Health Services, 10230 - 111 Avenue NW, Edmonton, Alberta, T5G 0B7, Canada; Faculty of Medicine and Dentistry, University of Alberta, W.C. Mackenzie Health Sciences Centre, 8440 - 112 Street NW, Edmonton, Alberta, T6G 2R7, Canada.

Background: Dynamic pedobarography is used to measure the change in plantar pressure distribution during gait. Clinical methods of pedobarographic analysis lack, however, a standardized, functional segmentation or require costly motion capture technology and expertise. Furthermore, while commonly used pedobarographic measures are mostly based on peak pressures, progressive foot deformities also depend on the duration the pressure is applied, which can be quantified via impulse measures. Read More

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http://dx.doi.org/10.1016/j.gaitpost.2018.09.029DOI Listing
January 2019

Benefits of crowd-sourced GPS information for modelling the recreation ecosystem service.

PLoS One 2018 15;13(10):e0202645. Epub 2018 Oct 15.

Laboratoire d'Ecologie Alpine, CNRS-Université Grenoble Alpes, CS, Grenoble, France.

Modelling cultural ecosystem services is an enduring challenge, raising issues about the integration and spatialization of immaterial values and benefits, and their contingency on local preferences. Building on the Recreation Opportunity Spectrum framework, we present a novel methodology for assessing the recreation service using GPS tracks downloaded from crowd-sourced websites: the Grelou model (Georeferencing REcreation in Local OUtdoors), here applied to the Grenoble living area (French Alps). GPS tracks revealed the complete spatial extent of visitor presence and enabled modelling visitation networks for ten recreation activities with great spatial accuracy, thus providing a spatial estimate of recreational multifunctionality-expressed as the sum of networks. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0202645PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188625PMC
March 2019
1 Read

Synthetic biology approaches and combinatorial biosynthesis towards heterologous lipopeptide production.

Chem Sci 2018 Oct 8;9(38):7510-7519. Epub 2018 Aug 8.

Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) , Helmholtz Centre for Infection Research and Department of Pharmacy at Saarland University , Saarland University Campus , Building E8.1 , 66123 Saarbrücken , Germany . Email:

Synthetic biology techniques coupled with heterologous secondary metabolite production offer opportunities for the discovery and optimisation of natural products. Here we developed a new assembly strategy based on type IIS endonucleases and elaborate synthetic DNA platforms, which could be used to seamlessly assemble and engineer biosynthetic gene clusters (BGCs). By applying this versatile tool, we designed and assembled more than thirty different artificial myxochromide BGCs, each around 30 kb in size, and established heterologous expression platforms using a derivative of DK1622 as a host. Read More

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http://dx.doi.org/10.1039/c8sc02046aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180311PMC
October 2018

A mechanoelectrical mechanism for detection of sound envelopes in the hearing organ.

Nat Commun 2018 10 9;9(1):4175. Epub 2018 Oct 9.

Oregon Hearing Research Center, Oregon Health & Science University, Portland, OR, 97239, USA.

To understand speech, the slowly varying outline, or envelope, of the acoustic stimulus is used to distinguish words. A small amount of information about the envelope is sufficient for speech recognition, but the mechanism used by the auditory system to extract the envelope is not known. Several different theories have been proposed, including envelope detection by auditory nerve dendrites as well as various mechanisms involving the sensory hair cells. Read More

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http://www.nature.com/articles/s41467-018-06725-w
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http://dx.doi.org/10.1038/s41467-018-06725-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177430PMC
October 2018
8 Reads
10.742 Impact Factor

The Accuracy Comparison of Three Simultaneous Localization and Mapping (SLAM)-Based Indoor Mapping Technologies.

Sensors (Basel) 2018 Sep 25;18(10). Epub 2018 Sep 25.

GNSS Research Center, Wuhan University, 129 Luoyu Road, Wuhan 430079, China.

The growing interest and the market for indoor Location Based Service (LBS) have been drivers for a huge demand for building data and reconstructing and updating of indoor maps in recent years. The traditional static surveying and mapping methods can't meet the requirements for accuracy, efficiency and productivity in a complicated indoor environment. Utilizing a Simultaneous Localization and Mapping (SLAM)-based mapping system with ranging and/or camera sensors providing point cloud data for the maps is an auspicious alternative to solve such challenges. Read More

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http://www.mdpi.com/1424-8220/18/10/3228
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http://dx.doi.org/10.3390/s18103228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210241PMC
September 2018
22 Reads

Integration among databases and data sets to support productive nanotechnology: Challenges and recommendations.

NanoImpact 2018 Jan;9:85-101

Center for the Environmental Implications of Nano Technology (CEINT) Duke University, Box 90287, 121 Hudson Hall, Durham, NC 27708-0287, USA.

Many groups within the broad field of nanoinformatics are already developing data repositories and analytical tools driven by their individual organizational goals. Integrating these data resources across disciplines and with non-nanotechnology resources can support multiple objectives by enabling the reuse of the same information. Integration can also serve as the impetus for novel scientific discoveries by providing the framework to support deeper data analyses. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24520748173013
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http://dx.doi.org/10.1016/j.impact.2017.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145474PMC
January 2018
12 Reads

Evaluating the Accessibility of Healthcare Facilities Using an Integrated Catchment Area Approach.

Int J Environ Res Public Health 2018 09 19;15(9). Epub 2018 Sep 19.

Faculty of Information Engineering, China University of Geosciences, 388 Lumo Road, Wuhan 430074, China.

Accessibility is a major method for evaluating the distribution of service facilities and identifying areas in shortage of service. Traditional accessibility methods, however, are largely model-based and do not consider the actual utilization of services, which may lead to results that are different from those obtained when people's actual behaviors are taken into account. Based on taxi GPS trajectory data, this paper proposed a novel integrated catchment area (ICA) that integrates actual human travel behavior to evaluate the accessibility to healthcare facilities in Shenzhen, China, using the enhanced two-step floating catchment area (E2SFCA) method. Read More

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http://www.mdpi.com/1660-4601/15/9/2051
Publisher Site
http://dx.doi.org/10.3390/ijerph15092051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164298PMC
September 2018
14 Reads

Nano based drug delivery systems: recent developments and future prospects.

J Nanobiotechnology 2018 Sep 19;16(1):71. Epub 2018 Sep 19.

Department of Food Science and Biotechnology, Dongguk University, Ilsandong-gu, Goyang, Gyeonggi-do, 10326, Republic of Korea.

Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic agents to specific targeted sites in a controlled manner. Nanotechnology offers multiple benefits in treating chronic human diseases by site-specific, and target-oriented delivery of precise medicines. Recently, there are a number of outstanding applications of the nanomedicine (chemotherapeutic agents, biological agents, immunotherapeutic agents etc. Read More

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https://jnanobiotechnology.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/s12951-018-0392-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145203PMC
September 2018
27 Reads

Future response of global coastal wetlands to sea-level rise.

Nature 2018 09 12;561(7722):231-234. Epub 2018 Sep 12.

Faculty of Engineering and the Environment, University of Southampton, Southampton, UK.

The response of coastal wetlands to sea-level rise during the twenty-first century remains uncertain. Global-scale projections suggest that between 20 and 90 per cent (for low and high sea-level rise scenarios, respectively) of the present-day coastal wetland area will be lost, which will in turn result in the loss of biodiversity and highly valued ecosystem services. These projections do not necessarily take into account all essential geomorphological and socio-economic system feedbacks. Read More

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http://dx.doi.org/10.1038/s41586-018-0476-5DOI Listing
September 2018

The sustainability of Lean in pediatric healthcare: a realist review.

Syst Rev 2018 09 11;7(1):137. Epub 2018 Sep 11.

Faculty of Nursing, Level 3, Edmonton Clinic Health Academy, University of Alberta, 11405 87 Avenue, Edmonton, AB, T6G 1C9, Canada.

Background: Lean is a quality improvement management system from the Toyota manufacturing industry. Since the early 2000's, Lean has been used as an intervention for healthcare improvement. Lean is intended to reduce costs and improve customer value through continuous improvement. Read More

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http://dx.doi.org/10.1186/s13643-018-0800-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134523PMC
September 2018
1 Read

Conceptualizing Health Promotion in Relation to Outpatient Healthcare Building Design: A Scoping Review.

HERD 2019 Jan 11;12(1):69-86. Epub 2018 Sep 11.

1 Division of Building Design, Department of Architecture and Civil Engineering, Chalmers University of Technology, Gothenburg, Sweden.

Objective:: This review explored different conceptualizations of health promotion in the context of, and in relation to, outpatient building design.

Background:: Today's healthcare organizations are implementing holistic healthcare approaches such as health promotion, while simultaneously increasing their outpatient services. These health promotion approaches, focused on empowering people to take control of their health, are expected to have implications for the outpatient healthcare building design. Read More

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http://dx.doi.org/10.1177/1937586718796651DOI Listing
January 2019
1 Read

Perceptions of professional role in community mental health nurses: The interplay of power relations between nurses and mentally ill individuals.

Arch Psychiatr Nurs 2018 10 20;32(5):677-687. Epub 2018 Mar 20.

Faculty of Nursing, University of Alberta, 5-262 Edmonton Clinic Health Academy (ECHA) & 4-130E Clinical Sciences Building, 11405-87th Ave., Edmonton, Alberta T6G 1C9, Canada. Electronic address:

Nurses' professional role perception is related to the quality and safety of care. Limited data exist regarding professional role perception in community mental health nurses (CMHNs). The aim of the present study was to investigate the living experience of Greek-Cypriot CMHNs of their professional role. Read More

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http://dx.doi.org/10.1016/j.apnu.2018.03.007DOI Listing
October 2018

Systematic review of the effects of agricultural interventions on food security in northern Ghana.

PLoS One 2018 7;13(9):e0203605. Epub 2018 Sep 7.

Department of Biological, Environmental & Occupational Health Sciences, School of Public Health, College of Health Sciences, University of Ghana, Accra, Ghana.

Background: Food insecurity and poverty rates in Ghana are highest in the districts from latitude 8° N upwards. These have motivated several interventions aimed at addressing the food insecurity via promoting agricultural growth. An assessment of the overall impact of these interventions on food security is necessary to guide policy design and future interventions. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203605PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128573PMC
February 2019

Flower Strips in Wheat Intercropping System: Effect on Pollinator Abundance and Diversity in Belgium.

Insects 2018 Sep 4;9(3). Epub 2018 Sep 4.

Functional and Evolutionary Entomology, Department of Agronomy, Biology and Chemistry, Gembloux Agro-Bio Tech, University of Liege, Passage des Déportés 2, 5030 Gembloux, Belgium.

The decline of pollinators in agricultural areas has been observed for some decades, this being partly due to landscape simplification in intensive agrosystems. Diversifying agricultural landscapes by sowing flower strips within fields could reduce these adverse effects on biodiversity. In this context, the study presented here aimed at assessing and comparing the abundance and diversity of bees (Hymenoptera: Anthophila) and hoverflies (Diptera: Syrphidae) found and visiting flowers in three types of flower strips in Belgium: (i) a mixture of 11 wild flowers, (ii) a monofloral strip of (Asteraceae) and (iii) a monofloral strip of (Brassicaceae), where the last two are considered to be intercrops since they are valuable on the market, all sown within a field of winter wheat ( L. Read More

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http://dx.doi.org/10.3390/insects9030114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164983PMC
September 2018

Qualitative assessment of facilitators and barriers to HIV programme implementation by community health workers in Mopani district, South Africa.

PLoS One 2018 30;13(8):e0203081. Epub 2018 Aug 30.

Anova Health Institute, Johannesburg, South Africa.

South Africa has implemented a community-based HIV programme (CBHP) in its primary healthcare (PHC) re-engineering strategy that aims to improve public healthcare delivery. This CBHP is delivered by ward-based outreach teams (WBOTs); provision of community HIV services comprises an important component of this programme. We conducted an exploratory study to determine the facilitators and barriers to successful implementation of this CBHP in rural Mopani District, South Africa. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203081PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117027PMC
February 2019
27 Reads

Using Strategic Adaptive Management to Facilitate Implementation of Environmental Flow Programs in Complex Social-Ecological Systems.

Environ Manage 2018 11 25;62(5):955-967. Epub 2018 Aug 25.

Institute for Land, Water and Society, Charles Sturt University, PO BOX 789, Albury, New South Wales, 2640, Australia.

Freshwater resource management is becoming increasingly complex as human pressure increases on available water resources, and as more participatory transparent decision-making frameworks are being advocated within water management. Complexity is further increased when environmental flow programs are integrated into existing water management programs. Adaptive management frameworks present an obvious choice for integration and implementation of environmental flows, but have so far failed to become the dominant framework. Read More

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http://dx.doi.org/10.1007/s00267-018-1091-9DOI Listing
November 2018

The everyday practice of supporting health system development: learning from how an externally-led intervention was implemented in Mozambique.

Health Policy Plan 2018 Sep;33(7):801-810

Health Policy and Systems Division, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.

Health system strengthening (HSS) has often been undertaken by global health actors working through vertical programmes. However, experience has shown the challenges of this approach, and the need to recognize health systems as open complex adaptive systems-which in turn has implications for the design and implementation approach of more 'horizontal' HSS interventions. From 2009 to 2016, the Doris Duke Charitable Foundation supported the African Health Initiative, establishing Population Health Implementation and Training partnerships in five African countries (Ghana, Mozambique, Rwanda, Tanzania and Zambia). Read More

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http://dx.doi.org/10.1093/heapol/czy051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097456PMC
September 2018
8 Reads