3,304 results match your criteria Buerger Disease Thromboangiitis Obliterans


The IL-33/sST2 Axis in Thromboangiitis Obliterans.

J Inflamm Res 2020 16;13:317-323. Epub 2020 Jul 16.

Immunology Research Center, Inflammation and Inflammatory Diseases Division, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Background: Until recently, it remains unknown whether thromboangiitis obliterans (TAO) is a type of systemic vasculitis. A high level of IL-33 and its soluble decoy receptor sST2 in the acute phase of systemic vasculitis has been demonstrated.

Methods: The serum level of IL-33 and sST2 in 50 TAO patients, 20 age- and smoking habit-matched controls and 19 age-matched non-smoker controls was evaluated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/JIR.S253980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371438PMC

Herbal therapy treatment in thromboangiitis obliterans: a retrospective clinical study.

Ann Palliat Med 2020 Jul 14;9(4):1696-1707. Epub 2020 Jul 14.

Department of Vascular Surgery (4th Surgical Department), Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.

Background: Critical limb ischemia in patients with thromboangiitis obliterans (TAO, Buerger's disease) is associated with refractory rest pain, gangrene, and increased rates of amputation. Tuoju lotion was prepared by the Pharmacy Department of Dongfang Hospital. The focus of the study is to elicit the efficacy of the addition of Herbal therapy treatment to conventional treatment in TAO patients with severe extremity pain and to assess any statistically significant benefits in patient's pain control at rest. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm-19-578DOI Listing

Thromboangiitis obliterans: Aggressive angioplasty provides a potential solution (randomized pilot study).

SAGE Open Med 2020 4;8:2050312120927636. Epub 2020 Jun 4.

Department of Vascular Surgery, Mansoura University, Mansoura, Egypt.

Background: Thromboangiitis obliterans is an inflammatory disease affecting both medium- and small-sized vessels. Vasodilators, antiplatelets were proposed for treatment but the effect was minimal.

Objective: This study was conducted to investigate the effect of balloon angioplasty on patients with Buerger's disease compared to medical treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2050312120927636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278296PMC

The Efficacy of Percutaneous Transluminal Angioplasty on the Limb Salvage and Recovery of Symptoms in Patients With Buerger's Disease With Critical Limb Ischemia.

J Invasive Cardiol 2020 Jun;32(6):E158-E167

Kadikoy Medicana Hospital, Zuhtupasa Recep Peker Caddesi No:11, 34724 Mahallesi, 34724, Kadıkoy/Istanbul - Turkey.

Introduction: Buerger's disease, or thromboangiitis obliterans, is associated with limb-threatening chronic arterial lesions. In this study, we sought to investigate the efficacy of the percutaneous transluminal angioplasty method for the treatment of critical limb ischemia (CLI) in patients with Buerger's disease in our modest cohort.

Methods: Patients diagnosed with CLI secondary to Buerger's disease who underwent percutaneous transluminal angioplasty between May 2014 and June 2017 were retrospectively investigated. Read More

View Article

Download full-text PDF

Source

Pharmacological treatment for Buerger's disease.

Cochrane Database Syst Rev 2020 05 4;5:CD011033. Epub 2020 May 4.

Evidence Based Medicine, Cochrane Brazil, Universidade Federal de São Paulo, São Paulo, Brazil.

Background: Buerger's disease (thromboangiitis obliterans) is a non-atherosclerotic, segmental inflammatory pathology that most commonly affects the small and medium sized arteries, veins, and nerves in the upper and lower extremities. The aetiology is unknown, but involves hereditary susceptibility, tobacco exposure, immune and coagulation responses. In many cases, there is no possibility of revascularisation to improve the condition. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/14651858.CD011033.pub4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197514PMC

Did the Clinical Spectrum of Thromboangiitis Obliterans Change in the Past 40 Years?

Angiology 2020 08 22;71(7):621-625. Epub 2020 Apr 22.

Department of Internal Medicine, Hôpital HURIEZ, CHRU Lille, France.

Thromboangiitis obliterans (TAO) is an inflammatory disease that usually affects small and medium-sized arteries in the upper and lower limbs of young smokers. Previous studies showed that the spectrum TAO has changed in the 80s: the male-to-female ratio decreased, older patients were diagnosed, and upper limb involvement was more common. The aim of our study was to assess the changing clinical spectrum of TAO in France during the past 40 years. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0003319720920163DOI Listing
August 2020
2.370 Impact Factor

[Lower limb ischemia cured by stimulation electrode implantation assisted with microendoscopic discectomy system: A case report].

Authors:
Y L Qian S Xu H Y Liu

Beijing Da Xue Xue Bao Yi Xue Ban 2020 Apr;52(2):378-381

Department of Spinal Surgery, Peking University People's Hospital, Beijing 100044, China.

A 58-year-old male patient diagnosed with thromboangiitis obliterans (Fontaine stage IV) was recently treated with microendoscope discectomy system-assisted spinal cord stimulation electrode implantation and cured by department of vascular surgery combined with department of spinal surgery at Peking University People's Hospital. The patient suffered from cold injury to the right foot 14 years ago, which was cold, painful, numb, and then the toe was ulcerated and gangrene. Only the right foot small toe was left. Read More

View Article

Download full-text PDF

Source

The Effects of Spinal Cord Stimulators on End Organ Perfusion: A Literature Review.

Cureus 2020 Mar 12;12(3):e7253. Epub 2020 Mar 12.

Neurology, Allegheny Health Network, Pittsburgh, USA.

Spinal cord stimulators (SCS) have been gaining momentum in the last decade as their role in the management of chronic pain has become more apparent. Our intention was to search, analyze and highlight the effects of spinal cord stimulators on end-organ perfusion. We also looked at vascular diseases of atherosclerotic and nonatherosclerotic nature by examining objective evidence of improved circulation, pain control, limb salvage, and quality of life. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.7253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152574PMC

Impact of Therapeutic Angiogenesis Using Autologous Bone Marrow-derived Mononuclear Cell Implantation in Patients with No-option Critical Limb Ischemia.

Ann Vasc Dis 2020 Mar;13(1):13-22

Department of Cardiovascular Medicine, Kyoto Prefectural University of Medicine, Kyoto, Kyoto, Japan.

Recently, the limb salvage rate of patients with critical limb ischemia (CLI) has been improved due to the development of revascularization and wound care treatment. However, many patients with CLI are refractory to standard treatments, including revascularization such as endovascular treatment or surgical bypass. Establishment of a new cell therapy is required to improve the limb salvage rate and prognosis in patients with CLI. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3400/avd.ra.20-00002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140169PMC

The Imbalance among Oxidative Biomarkers and Antioxidant Defense Systems in Thromboangiitis Obliterans (Winiwarter-Buerger Disease).

J Clin Med 2020 Apr 7;9(4). Epub 2020 Apr 7.

Department of Biomolecular Sciences, Section of Biochemistry and Biotechnology, University "Carlo Bo" of Urbino, 61029 Urbino (PU), Italy.

(1) Background: Thromboangiitis obliterans or Winiwarter-Buerger disease (WBD), is an inflammatory, thrombotic occlusive, peripheral vascular disease, usually occurring in young smokers. The pathophysiological mechanisms underlying the disease are not clearly understood. The aim of this study is to investigate the imbalance between oxidants and antioxidants occurring in these patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jcm9041036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231233PMC

A plasma metabonomics study on the therapeutic effects of the Si-miao-yong-an decoction in hyperlipidemic rats.

J Ethnopharmacol 2020 Jun 25;256:112780. Epub 2020 Mar 25.

Department of Pharmacy, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China. Electronic address:

Ethnopharmacological Relevance: The Si-miao-yong-an decoction (SMYAD) is a famous traditional Chinese medicinal formula that has been used for centuries in ancient China for treating thromboangiitis obliterans. Because of its long history of use, it has been used to treat patients in China for thousands of years. In recent years, SMYAD has been widely used for treating cardiovascular and endocrine diseases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jep.2020.112780DOI Listing

Cotinine aggravates inflammatory response in thromboangiitis obliterans through TLR-4/MyD88/NF-κB inflammatory signaling pathway.

Int Angiol 2020 Jun 26;39(3):261-262. Epub 2020 Mar 26.

Department of Vascular Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.23736/S0392-9590.20.04327-8DOI Listing

Humoral and cellular immune response to Buerger's disease.

Vascular 2020 Aug 25;28(4):457-464. Epub 2020 Mar 25.

Vascular and Endovascular Surgery Research Center, Mashhad University of Medical Science, Mashhad, Iran.

Objective: Thromboangiitis obliterans is a nonatherosclerotic occlusive disease, affecting small to moderate sized arteries of the upper and lower extremities, leading to progressive inflammation and clot formation. However, the role of humoral and cell-mediated immunity in the development of this disease has not been clearly identified. The present study was intended to investigate the humoral and cellular immune response in patients with Buerger's disease with different disease severity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1708538120910055DOI Listing

Therapeutic Angiogenesis Using Bone Marrow Mononuclear Cell Transplantation - A New Standard Treatment for Thromboangiitis Obliterans?

Circ J 2020 Mar 13;84(4):549-550. Epub 2020 Mar 13.

Department of Cardiology, Nagoya University Graduate School of Medicine.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1253/circj.CJ-20-0137DOI Listing

Long-Term Clinical Outcomes of Autologous Bone Marrow Mononuclear Cell Implantation in Patients With Severe Thromboangiitis Obliterans.

Circ J 2020 Mar 3;84(4):650-655. Epub 2020 Mar 3.

Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University.

Background: Patients with severe Buerger disease, also known as thromboangiitis obliterans (TAO), are at risk of major limb amputation. It has been shown that autologous bone marrow mononuclear cell (BM-MNC) implantation improves the condition of critical limb ischemia in TAO patients. This study was conducted to further clarify the long-term (>10 years) results of autologous BM-MNC implantation in patients with TAO. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1253/circj.CJ-19-1041DOI Listing

D-dimer levels in patients with thromboangiitis obliterans.

Natl Med J India 2019 May-Jun;32(3):134-136

Department of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India.

Background: Thromboangiitis obliterans (TAO) or Buerger disease is a recurring progressive segmental vasculopathy that presents with inflammation and thrombosis of small and medium arteries and veins of the hands and feet. The exact cause remains unknown, with tobacco use (primarily smoking but also smokeless tobacco) being highly associated with the disease. The diagnosis is clinical and the lack of a diagnostic gold standard is a deterrent to diagnosing it in patients with atypical presentations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/0970-258X.278685DOI Listing

Detection of Rickettsia Endosymbiont Bemisia Tabaci in the Amputated Limbs of Three Buerger's Disease Patients.

Int Med Case Rep J 2020 18;13:33-40. Epub 2020 Feb 18.

Surgery Department, Farabi Hospital, Mashhad, Iran.

Until recently, the aetiology of Buerger's disease (BD) has been unknown. Although there is a close relationship between BD and smoking, it cannot explain the low prevalence of BD among smokers or the disease's geographical distribution. Infectious pathogens, such as Rickettsial infection, have also been suggested as the trigger of BD development, but this theory has neither been proven nor ruled out. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/IMCRJ.S225839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035904PMC
February 2020

Establishment of optimal exercise therapy using near-infrared spectroscopy monitoring of tissue muscle oxygenation after therapeutic angiogenesis for patients with critical limb ischemia: A multicenter, randomized, controlled trial.

Contemp Clin Trials Commun 2020 Mar 4;17:100542. Epub 2020 Feb 4.

Department of Cardiovascular Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Critical limb ischemia (CLI) is a potentially life-threatening condition that involves severely reduced blood flow to the peripheral arteries due to arteriosclerosis obliterans (ASO) of the limbs or a similar condition. CLI patients must undergo revascularization to avoid amputation of the lower limbs and improve their survival prognosis. However, the outcomes of conventional surgical revascularization or endovascular therapy are inadequate; therefore, establishing further effective treatment methods is an urgent task. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.conctc.2020.100542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015992PMC

[56-year old patient with acroasphyxia].

Dtsch Med Wochenschr 2020 02 4;145(3):187-188. Epub 2020 Feb 4.

Abt. für Rheumatologie und Immunologie, Justus-Liebig-Universität Gießen, Campus Kerckhoff, Bad Nauheim.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/a-1038-9819DOI Listing
February 2020

[Intervention of Vascular Dysplasia Caused by Different Mechanisms - Anlotinib for Right Lung Squamous Cell Carcinoma Combined with Thromboangiitis Obliterans: A Case Report and Literature Review].

Zhongguo Fei Ai Za Zhi 2020 Jan;23(1):60-64

Department of Respiratory and Critical Care Medicine, Shanghai General Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.

Background: To date, there is no effective treatment for thromboangiitis obliterans (TAO). Anlotinib, as a third-line therapy, is recommended for patients with refractory advanced non-small cell lung cancer (NSCLC). We presented a case report of a patient suffering from right lung squamous cell carcinoma combined with thromboangiitis obliterans, and analyzed the treatment dilemma, which provided a new idea for the treatment of these two diseases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3779/j.issn.1009-3419.2020.01.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007391PMC
January 2020

Woman With Finger Pain.

Ann Emerg Med 2020 01;75(1):19-56

Department of Emergency Medicine, Cook County Health, Chicago, IL.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.annemergmed.2019.07.013DOI Listing
January 2020

"Idiopathic Eosinophilic Vasculitis": Another Side of Hypereosinophilic Syndrome? A Comprehensive Analysis of 117 Cases in Asthma-Free Patients.

J Allergy Clin Immunol Pract 2020 Apr 18;8(4):1329-1340.e3. Epub 2019 Dec 18.

Centre de Référence National des Syndromes Hyperéosinophiliques (CEREO), Lille, France; Hôpital Ambroise Paré, Service de Médecine Interne, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.

Background: The absence of asthma may rule out a diagnosis of eosinophilic granulomatosis with polyangiitis in patients with hypereosinophilic syndrome (HES) and features of vasculitis.

Objective: To describe eosinophilic vasculitis (EoV) as a possible manifestation of HES in asthma-free patients.

Methods: We screened our hospital database and the literature for patients with HES who met the following 4 criteria: (1) histopathological or clinical features of EoV (biopsy-proven vasculitis with predominant eosinophilic infiltration of the vessel wall and/or features of vasculitis with tissue and/or blood hypereosinophilia [absolute eosinophil count >1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaip.2019.12.011DOI Listing

How to use clinical signs and symptoms to estimate the probability of limb ischaemia in patients with a diabetic foot ulcer.

Authors:
Edward J Boyko

Diabetes Metab Res Rev 2020 03 16;36 Suppl 1:e3241. Epub 2019 Dec 16.

Epidemiologic Research and Information Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington.

Assessment of ischaemia and interventions to improve perfusion are key elements in the management of the diabetic foot ulcer to achieve wound healing. This article will review, analyse and interpret the value of clinical information in determining the likelihood of limb ischaemia and thereby the need for referral to a vascular specialist. I conducted an historical review of the genesis of several currently recommended clinical signs and their diagnostic properties in the assessment of limb ischaemia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/dmrr.3241DOI Listing

The Association of HLA-A, B and DRB1 with Buerger's Disease.

Rep Biochem Mol Biol 2019 Jul;8(2):153-160

Immunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Background: Thromboangiitis obliterans (TAO), also known as Burger's disease, is a devastating disease affecting the arteries and veins of the upper and lower distal limbs most commonly afflicting young male smokers of low socioeconomic status. The expression of human leukocyte antigen (HLA)-A, B and -DRB1 genes have been implicated in the pathogenesis of TAO. Our study aimed to examine the association of different HLA-A, B and -DRB1 genes in TAO patients in the Iranian population. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844607PMC

Effect of bradykinin on rats with thromboangiitis obliterans through PI3K/Akt signaling pathway.

Eur Rev Med Pharmacol Sci 2019 Nov;23(22):10169-10176

Department of Vascular Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.

Objective: To explore the effect of bradykinin on rats with thromboangiitis obliterans (TAO) through the phosphatidylinositol 3-hydroxy kinase/protein kinase B (PI3K/Akt) signaling pathway.

Materials And Methods: The female Wistar rats were injected with lauric acid via the femoral artery to establish the TAO model, and they were randomly divided into control group (healthy rats), model group (TAO rats) and bradykinin group (TAO rats injected with bradykinin B2 receptor-specific inhibitor). The control was set in each group before the operation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.26355/eurrev_201911_19587DOI Listing
November 2019

Protective effects and potential mechanism of salvianolic acid B on sodium laurate-induced thromboangiitis obliterans in rats.

Phytomedicine 2020 Jan 15;66:153110. Epub 2019 Oct 15.

Department of Natural Products Chemistry, Key Lab of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, P.R. China. Electronic address:

Background: The root of Salvia miltiorrhiza f. alba (RSMA) (Lamiaceae) is used for the treatment of patients with thromboangiitis obliterans (TAO) in traditional Chinese medicine. Previously, a mixture of phenolic acids extracted from RSMA has shown significant protective effects on TAO rats. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phymed.2019.153110DOI Listing
January 2020

Successful Fat Grafting in a Patient With Thromboangiitis Obliterans.

Adv Skin Wound Care 2019 Dec;32(12):1-4

In Milan, Italy, Ilenia D'Alessio, MD, is a trainee, Department of Vascular Surgery, Fondazione IRCCS Policlinico; Alberto M. Settembrini, MD, is a surgeon, Department of Vascular Surgery, Fondazione IRCCS Policlinico; Silvia Romagnoli, MD, is a surgeon, Department of Vascular Surgery, Fondazione IRCCS Policlinico; Gabriele Di Luca, MD, is a surgeon, Section of Vascular Surgery, ASST Gaetano Pini; Maurizio Domanin, MD, is a surgeon, Department of Vascular Surgery, Fondazione IRCCS Policlinico; and Livio Gabrielli, MD, is a professor of vascular surgery, University of Milan. The authors have disclosed no financial relationships related to this article. Submitted April 10, 2019; accepted in revised form July 9, 2019.

Thromboangiitis obliterans, or Buerger disease, is a rare nonatherosclerotic segmental inflammatory vasculitis that generally affects young tobacco smokers. Although no surgical treatment is available, the most effective way to halt the disease's progress is smoking cessation. In this case report, a 29-year-old smoker showed up to emergency department with gangrene of his fifth left toe and extensive plantar ulceration. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.ASW.0000604192.77577.6fDOI Listing
December 2019

Fibrinogen, Neutrophil-to-Lymphocyte Rate and Platelet-to-Neutrophil Rate as Novel Acute Phase Indicators in Patients with Thromboangiitis Obliterans.

Ann Vasc Surg 2020 May 16;65:137-144. Epub 2019 Nov 16.

Department of the Lymphatic and Vascular Surgery, China-Japan Union Hospital of Jilin University, Changchun, China. Electronic address:

Background/objectives: The acute exacerbations and progressive deterioration seen in thromboangiitis obliterans (TAO) have been related to poor clinical outcomes. Here, we have studied the association of laboratory biomarkers with the acute phase of TAO (AP-TAO).

Methods/results: We conducted a retrospective case-control study on 112 patients with TAO and 98 healthy controls; comparing the neutrophil-to-lymphocyte rate (NLR), lymphocyte-to-monocyte rate (LMR), platelet-to-neutrophil rate (PNR), fibrinogen (FIB), and apolipoprotein A-I (ApoA-I). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.avsg.2019.11.020DOI Listing

Visceral bed involvement in thromboangiitis obliterans: a systematic review.

Vasc Health Risk Manag 2019 15;15:317-353. Epub 2019 Aug 15.

Immunology Research Center, Inflammation and Inflammatory Diseases Division, Immunology Department, School of Medicine, Mashhad University of Medical Sciences , Mashhad, Iran.

One of the challenges of thromboangiitis obliterans (TAO) management is in the patients whose other vascular beds are involved and it remains a challenge to know whether to pursue invasive procedures or to continue medical treatment for such TAO patients. The aim of this review was to investigate reports of the involvement of the visceral vessels in TAO and the related clinical manifestations, management approaches and outcomes. According to our systematic review, the frequency of published articles, the organs most commonly involved were the gastrointestinal tract, the heart, the central nervous system, the eye, the kidneys, the urogenital system, the mucocutaneous zones, joints, lymphohematopoietic system and the ear. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/VHRM.S182450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699490PMC
December 2019
1 Read

A Non-smoking Woman with Anti-phospholipid Antibodies Proved to Have Thromboangiitis Obliterans.

Intern Med 2020 Feb 7;59(3):439-443. Epub 2019 Oct 7.

Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Japan.

A 48-year-old woman with severe pain and numbness of her right leg and foot was admitted to our hospital. She had never smoked and had little exposure to passive smoking. Initially, polyarteritis nodosa with anti-phospholipid antibodies was considered. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2169/internalmedicine.3372-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028403PMC
February 2020
2 Reads

Assessment of T helper 17-associated cytokines in thromboangiitis obliterans.

J Inflamm Res 2019 5;12:251-258. Epub 2019 Sep 5.

Immunology Department, Immunology Research Center, Inflammation and Inflammatory Diseases Division, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Background: The management of thromboangiitis obliterans (TAO) remains a medical challenge because of its unknown etiology. It is also not known whether it is a systemic or localized disease or a type of autoimmune vasculitis.

Methods: In this study, we evaluated the serum level of IL-17 and IL-23 which increase in both systemic inflammation and autoimmunity, in 60 TAO patients and 30 age- and smoking habit-matched controls. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/JIR.S218105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734553PMC
September 2019
1 Read

Demonstration of Corkscrew Collaterals in Buerger's Disease by Superb Microvascular Imaging.

Can J Cardiol 2019 09 8;35(9):1256.e3-1256.e4. Epub 2019 May 8.

Department of Radiology, Uludag University Faculty of Medicine, Bursa, Turkey.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cjca.2019.05.002DOI Listing
September 2019
1 Read

Associations Between Elevated Plasma Total Homocysteine Level and Risk of Thromboangiitis Obliterans in a Chinese Population: A Matched Case-Control Study.

Ann Vasc Surg 2020 Jan 28;62:335-341. Epub 2019 Aug 28.

Department of Vascular and Endovascular Surgery, Chinese PLA General Hospital, Beijing, China. Electronic address:

Background: Elevated plasma total homocysteine level is a risk factor for various vascular diseases; however, an association with risk of thromboangiitis obliterans (TAO) has not been defined. This study aims to assess whether elevated plasma total homocysteine level is associated with risk of TAO.

Methods: We performed a matched case-control study including 64 patients with TAO and 256 controls. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.avsg.2019.06.026DOI Listing
January 2020
3 Reads

Risk of immune-mediated inflammatory diseases in newly diagnosed ankylosing spondylitis patients: a population-based matched cohort study.

Arthritis Res Ther 2019 08 29;21(1):196. Epub 2019 Aug 29.

Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.

Objective: To investigate the risk of immune-mediated inflammatory diseases (IMIDs) in patients with ankylosing spondylitis (AS).

Methods: Using 2003-2012 claims data from the Taiwanese National Health Insurance Research Database, we identified 30,911 newly diagnosed AS patients requiring medical therapy from 2006 to 2012. In addition, we randomly selected 309,110 non-AS individuals matching (1:10) the AS patients with regard to age, sex and the year of the index date. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13075-019-1980-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716905PMC
August 2019
2 Reads
3.753 Impact Factor

Management of Buerger's Disease in Endovascular Era.

Int J Angiol 2019 Sep 19;28(3):173-181. Epub 2019 Apr 19.

Vascular Surgery Department, Faculty of Medicine, Cairo University, Egypt.

This study was aimed to report data on the feasibility, safety, and effectiveness of endovascular procedures in a thromboangiitis obliterans diagnosed patients presenting with critical limb ischemia (CLI). Prospective study conducted on patients affected by Buerger's disease who presented to our center along 2 years. Clinical, radiological, and patient-based outcomes were recorded at 3, 6, and 12 months after the intervention. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0039-1685200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707802PMC
September 2019
2 Reads

Risk Factors, Mechanisms and Treatments of Thromboangiitis Obliterans: An Overview of Recent Research.

Curr Med Chem 2019 Aug 16. Epub 2019 Aug 16.

Department of Physiology, College of Medicine, Nanchang University, Nanchang 330006,. China.

Background: Thromboangiitis obliterans (TAO) is a nonatherosclerotic thrombotic-occlusive vasculitis that affects the vessels of the small and medium sized extremities. No explicit etiology or pathogenesis of TAO has been proven, and more effective treatments are needed.

Objective: To summarize and present an overview of recent advances regarding the risk factors, mechanisms and treatments of TAO and to organize the related information into figures to provide a comparatively complete reference. Read More

View Article

Download full-text PDF

Source
http://www.eurekaselect.com/174274/article
Publisher Site
http://dx.doi.org/10.2174/0929867326666190816233042DOI Listing
August 2019
9 Reads

Botany, traditional uses, phytochemistry, pharmacology and toxicology of Ilex pubescens Hook et Arn.

J Ethnopharmacol 2019 Dec 8;245:112147. Epub 2019 Aug 8.

School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China. Electronic address:

Ethnopharmacological Relevance: Ilex pubescens (I. pubescens), which is well known in Chinese as Mao-Dong-Qing, is widely used in traditional Chinese medicine. This plant is distributed in the wild in southern China, and the roots and stems are used for clearing heat, detoxifying, activating blood circulation and dispelling stasis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jep.2019.112147DOI Listing
December 2019
6 Reads

Angiogenesis induction in Buerger's disease: a disease management double-edged sword?

Orphanet J Rare Dis 2019 08 5;14(1):189. Epub 2019 Aug 5.

Surgery Department, Farabi Hospital, Mashhad, Iran.

Due to unknown aetiology of Thromboangiitis obliterans (TAO), its effectively treating is challenging. However, angiogenesis induction is one of the acceptable treatments for TAO patients. Recently, we have noticed that TAO patients who were under long-term treatment with angiogenesis-inducing medication showed considerable improvement in terms of healing chronic ulcers over the course of one to 2 years of treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13023-019-1166-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683384PMC
August 2019
5 Reads

Case report of two pregnancies and deliveries by a woman with Buerger disease.

J Obstet Gynaecol Res 2019 Oct 31;45(10):2100-2104. Epub 2019 Jul 31.

Department of Anesthesiology and Pain Medicine, Juntendo University Urayasu Hospital, Urayasu-shi, Chiba, Japan.

Buerger disease is a chronic inflammatory disease that involves blood clot formation in the medium and small arteries, resulting in thrombophlebitis. It is usually observed in middle-aged men who smoke and is very rare in young women. Previous reports have indicated that Buerger disease worsens during pregnancy due to hypercoagulability associated with pregnancy, and newborns' birth weights were often lower than normal. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jog.14087DOI Listing
October 2019
1 Read

Antiphospholipid antibodies in Buerger's disease.

Thromb Res 2019 Sep 21;181:64-66. Epub 2019 Jul 21.

Immunology Research Center, Inflammation and Inflammatory Diseases Division, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; Vascular Independent Research and Education, European Foundation, Milan, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.thromres.2019.07.015DOI Listing
September 2019

Unexpected inflammation in the sympathetic ganglia in thromboangiitis obliterans: more likely sterile or infectious induced inflammation?

Clin Mol Allergy 2019 6;17:10. Epub 2019 Jul 6.

1Immunology Research Center, Inflammation and Inflammatory Diseases Division, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Introduction: The aim of this study was to determine if the inflammation of the sympathetic ganglia (SG) in thromboangiitis obliterans (TAO) is induced by an infectious pathogen inside or if it is a reactive sterile inflammation.

Methods: For the purpose of this study, the gene expression of high-mobility group box 1 (HMGB1), toll-like receptor 4 (TLR4), toll-like receptor 9 (TLR9), and the receptor for advanced glycation end-products (RAGE) were evaluated on the complementary DNA (cDNA) of the SG tissues of 24 TAO patients and two controls with hyperhidrosis by real-time polymerase chain reaction (PCR) and analysed by the Pfaffl method.

Results: The gene expression of HMGB1 and TLR9 increased by about 25- and 2-fold changes in the SG of the TAO patients, respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12948-019-0114-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612411PMC
July 2019
13 Reads

Never Underestimate a Concomitant Repairable Inflow Lesion in Buerger's Disease!

Int J Low Extrem Wounds 2019 Sep 14;18(3):342-343. Epub 2019 Jun 14.

Medical School, Democritus University of Thrace, Alexandroupolis, Greece.

A case of Buerger's disease is presented where percutaneous endovascular treatment of a concomitant focal stenosis in the superficial femoral artery led to immediate remission of symptoms and aided wound healing. The existence of such lesions should never be underestimated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1534734619854636DOI Listing
September 2019
8 Reads
1.194 Impact Factor

Molecular mechanisms regulating immune responses in thromboangiitis obliterans: A comprehensive review.

Iran J Basic Med Sci 2019 Mar;22(3):215-224

Immunology Research Group, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Thromboangiitis obliterans (TAO) is a thrombotic-occlusive as well as an inflammatory peripheral vascular disease with unknown etiology. Recent evidence has supported the immunopathogenesis of the disease, however, the factors contributing to the altered immune function and vascular tissue inflammation are still unclear. This review was intended to collate the more current knowledge on the regulatory molecules involved in TAO from an immunoreactive perspective. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.22038/ijbms.2019.31119.7513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528722PMC
March 2019
16 Reads
0.604 Impact Factor

Vaso-nervorumitis: responsible for pain in Buerger's disease?

Int Med Case Rep J 2019 29;12:119-123. Epub 2019 Apr 29.

Surgery Department, Farabi Hospital, Mashhad, Iran.

Buerger's disease (BD) is an episodic, inflammatory, and occlusive peripheral vascular disease with unknown etiology, which can lead to tissue or limb loss. BD patients usually present neurological symptoms from the early stages of the disease including numbness, cold sensation, and allodynia as the disease progresses. Pain in the late stages of BD is very severe, almost resistant to opioid pain killers, and sometimes compels the patient to pursue major amputation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/IMCRJ.S197862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503200PMC
April 2019
23 Reads

[Marijuana-associated peripheral arteriopathy].

Medicina (B Aires) 2019 ;79(2):144-146

Servicio de Clínica Médica, Hospital Británico de Buenos Aires, Argentina.

The marijuana arteriopathy should be considered in young patients with peripheral arterial disease with no risk factors for atherosclerosis. It was described for the first time in 1960 and since then there have been about 100 cases published in the literature. Although it tends to be considered as an independent entity of thromboangiitis obliterans or Leo Buerger's disease, in the light of the last findings it is possible to consider it within the spectrum of the latter. Read More

View Article

Download full-text PDF

Source
June 2019
10 Reads

[Acute carpal tunnel syndrome caused by a thrombosis of a persistent median artery: 2 case reports].

Rev Med Interne 2019 Jul 28;40(7):453-456. Epub 2019 Apr 28.

Service de médecine interne, Normandie université, UNIROUEN, 76031 Rouen, France.

Carpal tunnel syndrome is a common peripheral neuropathy, usually idiopathic or post-traumatic due to the compression of the median nerve. Numbness and paresthesias in the median nerve distribution are the most common symptoms associated with this condition. Persistent median artery is a rare anatomic variation, thrombosis of this additional artery can be responsible for an acute carpal tunnel syndrome, and patients frequently complain about coldness and acute hand swelling. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.revmed.2019.04.002DOI Listing
July 2019
9 Reads

[Comprehensive treatment of a patient with Buerger's disease using genetically engineered complexes VEGF-165].

Angiol Sosud Khir 2019 ;25(1):177-180

First Moscow State Medical University named after I.M. Sechenov under the RF Ministry of Public Health, Moscow, Russia; Scientific Clinical Centre of the Open Joint-Stock Company 'Russian Railways', Moscow, Russia.

Buerger's disease, also known as thromboangiitis obliterans, is a severe invalidating systemic vascular disease. To one of the modern methods, which is distinguished by its radically new principles of action, as well as holding much promise for further study and application in treatment of patients with lower limb chronic ischaemia induced by thromboangiitis obliterans belongs the use of genetically engineered complexes based on vascular endothelial growth factor VEGF-165 ('Neovasculgen'). 'Neovasculgen' is a genetically engineered complex being a circular DNA (native plasmid on the CELO vector and Ad5), carrying the human VEGF-165 gene, encoding VEGF synthesis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.33529/angio2019124DOI Listing
August 2019
31 Reads

Thromboangiitis Obliterans: Changing Demographics for a Preventable Disease.

Authors:
Ryan Stefancik

Cureus 2019 Jan 11;11(1):e3869. Epub 2019 Jan 11.

Osteopathy, University of Pikeville-Kentucky College of Osteopathic Medicine, Pikeville, USA.

Thromboangiitis obliterans (TAO), otherwise known as Buerger's Disease, is a rare, small-vessel vasculitis strongly associated with cigarette smoking, that when left untreated can cause vessel destruction and necrosis of the distal extremities leading to amputation. The patient being presented is a 46-year-old Caucasian female who has been smoking since the age of fifteen and shows characteristics of TAO on angiography. The uniqueness of this case lies in the epidemiology; the typical TAO patient is a 20 to 40-year-old Asian male. Read More

View Article

Download full-text PDF

Source
https://www.cureus.com/articles/16379-thromboangiitis-oblite
Publisher Site
http://dx.doi.org/10.7759/cureus.3869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414186PMC
January 2019
21 Reads

Mycophenolic acid-induced onychomadesis: An easily ignorable adverse effect in patients with rheumatic diseases.

Int J Rheum Dis 2019 Apr 12;22(4):753-755. Epub 2019 Mar 12.

Division of Rheumatology/Immunology and Allergy, Department of Internal Medicine, Tri-Service General Hospital, Taipei, Taiwan.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/1756-185X.13544
Publisher Site
http://dx.doi.org/10.1111/1756-185X.13544DOI Listing
April 2019
4 Reads