14,577 results match your criteria Brucellosis


Brucellosis in food-producing animals in Mosul, Iraq: A systematic review and meta-analysis.

Authors:
Mohammad O Dahl

PLoS One 2020 9;15(7):e0235862. Epub 2020 Jul 9.

Department of Internal and Preventive Medicine, College of Veterinary Medicine, University of Mosul, Mosul, Iraq.

Brucellosis is an endemic disease in food-producing animals in Mosul, Iraq. The objectives of the study reported here were: (i) to identify and assess the evidence and knowledge gaps in published studies that have examined brucellosis in different food-producing animals in Mosul, Iraq; using systematic review approach, and (ii) to quantify the seroprevalence of brucellosis in the city using meta-analysis approach. Google Scholar was used as a search engine to track pertinent peer-reviewed research reports. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235862PLOS

Epidemiological and clinical characteristics of bacteremic brucellosis.

J Int Med Res 2020 Jul;48(7):300060520936829

Department of Infectious Diseases, Tianjin Second People's Hospital, Tianjin, China.

Objective: To retrospectively investigate the epidemiological features, clinical manifestations and laboratory characteristics of bacteremic brucellosis.

Methods: Brucellosis patients admitted to our clinic from January 2015 to December 2017 were included in the study. Patient electronic medical records were reviewed for epidemiological features, clinical manifestations, and laboratory findings. Read More

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http://dx.doi.org/10.1177/0300060520936829DOI Listing

Spinal brucellosis with large circumscribed paraspinal and epidural abscess formation: a case report.

Br J Neurosurg 2020 Jul 9:1-5. Epub 2020 Jul 9.

Shiraz Neuroscience Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Human Brucellosis is a bacterial infection caused by species of Brucella, which can involve multiple organs and tissues. Spinal epidural abscesses are rare and may be complicated by potentially life threatening neurological or vascular compromise. We report a 21-year-old female with spinal brucellosis complicated by lumbar spondylodiscitis, epidural abscess and a large right-sided paraspinal abscess extended from L4 to sacrum. Read More

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http://dx.doi.org/10.1080/02688697.2020.1789557DOI Listing

Brucellosis causing subacute motor polyradiculopathy and the pathological correlation of pseudomyopathic electromyography: A case report.

Clin Neurophysiol Pract 2020 11;5:130-134. Epub 2020 Jun 11.

Neuromuscular Unit, King Fahad Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

Introduction: Brucellosis is a rare cause of polyradiculopathy. We aim to present a case of subacute motor polyradiculopathy (SAMPR), along with the electromyographic pseudomyopathic changes, and their histopathological correlation.

Case Presentation: A 24-year-old man presented with gradually progressive bilateral lower limb weakness for three weeks that progressed to a loss of ambulation in seven weeks. Read More

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http://dx.doi.org/10.1016/j.cnp.2020.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334466PMC

Probable sexual transmission of brucellosis.

IDCases 2020 15;21:e00871. Epub 2020 Jun 15.

The Key Laboratory of Infectious and Parasitic Diseases in Chongqing, Infectious Disease Department, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.

Brucellosis, a bacterial zoonosis, is transmitted directly or indirectly from infected animals (mainly domesticated ruminants and pigs) to humans. People are generally susceptible to brucella, which is mainly transmitted by direct contact, digestive tract and respiratory tract. Since brucella can be discharged from various secretions and feces after human infection, sexual transmission has become a potential mode of transmission. Read More

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http://dx.doi.org/10.1016/j.idcr.2020.e00871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334807PMC

Distribution of Class B and Class A β-Lactamases in Clinical Strains of : Comparison of Phenotypic Methods and High-Resolution Melting Analysis (HRMA) Assay.

Infect Drug Resist 2020 30;13:2037-2052. Epub 2020 Jun 30.

Microbiology Department, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Background: There are various phenotypic methods for identifying class B and class A β-lactamase enzymes in . The purpose of this study was to compare the sensitivity and specificity of different phenotypic methods with HRMA assay to detect β-lactamase-producing strains.

Methods: Eighty-eight of isolates were collected from different specimens. Read More

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http://dx.doi.org/10.2147/IDR.S255292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335274PMC

Genome-wide core proteome analysis of Brucella melitensis Strains for Potential Drug Target Prediction.

Mini Rev Med Chem 2020 Jul 7. Epub 2020 Jul 7.

University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore 54000. Pakistan.

Brucella melitensis is a facultative intracellular bacterial pathogen that causes abortion in goats and sheep and Malta fever in humans. Human chronic infection is successfully established through contact with infected animals or their dirty product. Subtractive genomic approach is considered as a powerful and useful method for the identification of potential drug and vaccine targets. Read More

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http://dx.doi.org/10.2174/1389557520666200707133347DOI Listing

Roxb. Inhibits Collagen Induced Adhesion and Migration of PC3 and LNCaP Prostate Cancer Cells through the Inhibition of Beta 1 Integrin Expression.

Molecules 2020 Jun 30;25(13). Epub 2020 Jun 30.

Department of Nano-Bioengineering, Incheon National University, 119 Academy-ro, Yeonsu-gu, Incheon 22012, Korea.

Roxb. (SGR) has been used as a traditional medicine for brucellosis and syphilis. In this study, we investigated whether nontoxicological levels of water extract of SGR (WESGR) are effective for suppressing steps in the progression of prostate cancer, such as collagen-mediated migration and adhesion and identified the target molecule responsible for such effects. Read More

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http://dx.doi.org/10.3390/molecules25133006DOI Listing

Hepatic Stellate Cells and Hepatocytes as Liver Antigen-Presenting Cells during Infection.

Pathogens 2020 Jun 30;9(7). Epub 2020 Jun 30.

Instituto de Inmunología, Genética y Metabolismo (INIGEM), Universidad de Buenos Aires, CONICET, Buenos Aires 1120, Argentina.

In Brucellosis, the role of hepatic stellate cells (HSCs) in the induction of liver fibrosis has been elucidated recently. Here, we study how the infection modulates the antigen-presenting capacity of LX-2 cells. infection induces the upregulation of class II transactivator protein (CIITA) with concomitant MHC-I and -II expression in LX-2 cells in a manner that is independent from the expression of the type 4 secretion system (T4SS). Read More

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http://dx.doi.org/10.3390/pathogens9070527DOI Listing

[Two cases of brucellosis concurrent testicularitis and diaphragm fluid].

Authors:
D Wu

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2020 Jun;38(6):460

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http://dx.doi.org/10.3760/cma.j.cn121094-20190819-00342DOI Listing

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): infection with and .

EFSA J 2017 Jul 20;15(7):e04889. Epub 2017 Jul 20.

The infection with , and has been assessed according to the criteria of the Animal Health Law (AHL), in particular criteria of Article 7 on disease profile and impacts, Article 5 on the eligibility of the infection with , and to be listed, Article 9 for the categorisation of the infection with , and according to disease prevention and control rules as in Annex IV and Article 8 on the list of animal species related to the infection with , and . The assessment has been performed following a methodology composed of information collection and compilation, expert judgement on each criterion at individual and, if no consensus was reached before, also at collective level. The output is composed of the categorical answer, and for the questions where no consensus was reached, the different supporting views are reported. Read More

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http://dx.doi.org/10.2903/j.efsa.2017.4889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009888PMC

The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2016.

Authors:

EFSA J 2017 Dec 12;15(12):e05077. Epub 2017 Dec 12.

This report of the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of the zoonoses monitoring activities carried out in 2016 in 37 European countries (28 Member States (MS) and nine non-MS). Campylobacteriosis was the most commonly reported zoonosis and the increasing European Union (EU) trend for confirmed human cases since 2008 stabilised during 2012-2016. In food, the occurrence of remained high in broiler meat. Read More

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http://dx.doi.org/10.2903/j.efsa.2017.5077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009962PMC
December 2017

Association of TNF rs668920841 and INRA111 polymorphisms with caprine brucellosis: A case-control study of candidate genes involved in innate immunity.

Genomics 2020 Jul 3. Epub 2020 Jul 3.

Instituto de Patobiología, CICVyA, INTA, Nicolás Repetto y de Los Reseros s/n, Hurlingham, B1686, Buenos Aires, Argentina. Electronic address:

Caprine brucellosis is an infectious, contagious zoonotic disease caused by Brucella melitensis. Multiple factors, including host genetics, can influence the outcome of the exposure to Brucella; and it is expected that genetic variants that affect the host innate immune response could have a key role in Brucella infection and pathogenesis. In this study, we evaluated if polymorphisms in innate immunity-related genes are associated with results of Brucella infection in goats. Read More

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http://dx.doi.org/10.1016/j.ygeno.2020.06.050DOI Listing

Brucella abortus-infected platelets modulate activation of neutrophils.

Immunol Cell Biol 2020 Jul 5. Epub 2020 Jul 5.

Instituto de Medicina Experimental (CONICET-Academia Nacional de Medicina), Buenos Aires, Argentina.

Brucellosis is a contagious disease caused by bacteria of the genus Brucella. Platelets have been widely involved in the modulation of the immune response. We have previously reported the modulation of Brucella abortus-mediated infection of monocytes. Read More

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http://dx.doi.org/10.1111/imcb.12373DOI Listing

Methods in isolation and characterization of bovine monocytes and macrophages.

Methods 2020 Jul 2. Epub 2020 Jul 2.

Department of Veterinary Medicine, Università degli Studi di Milano, Milan, Italy.

Monocytes and macrophages belong to the mononuclear phagocyte system and play important roles in both physiological and pathological processes. The cells belonging to the monocyte/macrophage system are structurally and functionally heterogeneous. Several subsets of monocytes have been previously identified in mammalian blood, generating different subpopulations of macrophages in tissues. Read More

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http://dx.doi.org/10.1016/j.ymeth.2020.06.017DOI Listing

Evaluation of the sensitivity and specificity of the lateral flow assay, Rose Bengal test and the complement fixation test for the diagnosis of brucellosis in cattle using Bayesian latent class analysis.

Prev Vet Med 2020 Jun 21;181:105075. Epub 2020 Jun 21.

Department of Paraclinical Veterinary Studies, Faculty of Veterinary Science, University of Zimbabwe, P.O. Box MP 167, Mount Pleasant, Harare, Zimbabwe. Electronic address:

This study was conducted to evaluate the sensitivity (Se) and specificity (Sp) of the Rose Bengal test (RBT), complement fixation test (CFT), the serum lateral flow assay (LFA) and the blood lateral flow assay (LFA) for the detection of antibodies to Brucella spp. using Bayesian latent class models (BLCMs). Sera and whole blood were collected from naturally infected cattle reared in smallholder, small-scale commercial and large-scale commercial farms in Zimbabwe (n = 1022) and Botswana (n = 770). Read More

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http://dx.doi.org/10.1016/j.prevetmed.2020.105075DOI Listing

Zoonotic brucellosis from the long view: Can the past contribute to the present?

Infect Control Hosp Epidemiol 2020 Jun 19:1-2. Epub 2020 Jun 19.

Veterinary Epidemiology, Economics and Public Health group, Department of Pathobiology and Population Sciences, Royal Veterinary College, University of London, Hatfield, England.

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http://dx.doi.org/10.1017/ice.2020.270DOI Listing

An insight into the transmission role of insect vectors based on the examination of gene characteristics of African swine fever virus originated from non-blood sucking flies in pig farm environments.

BMC Vet Res 2020 Jul 2;16(1):227. Epub 2020 Jul 2.

Key Laboratory of Livestock Infectious Diseases in Northeast China, Ministry of Education, College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, No.120, Dongling Road, Shenhe District, Shenyang, 110866, PR China.

Background: Insect vector transmitted pathogens from contaminated environments are a key potential risk for public health. Meanwhile, transmission by non-blood sucking flies needs to be considered. Sequencing and phylogenetic tree analyses were used to study African swine fever virus (ASFV) genes derived from flies collected from pig farms that were infected with ASFV. Read More

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http://dx.doi.org/10.1186/s12917-020-02420-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331130PMC

Psychometric Properties of a Questionnaire on Brucellosis Prevention Behaviors Based on the PRECEDE Model Among Rural Farmers and Their Family Members.

Risk Manag Healthc Policy 2020 9;13:539-548. Epub 2020 Jun 9.

Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Introduction: Brucellosis is one of the most prevalent diseases in Torbate Heidarieh, Iran; it is a common disease between human and animals. The present study aimed to review the psychometric properties of a questionnaire on brucellosis prevention behaviors based on the PRECEDE model among rural farmers and their family members (PRECEDE-QBPB).

Materials And Methods: The study was a combination of qualitative and quantitative stages. Read More

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http://dx.doi.org/10.2147/RMHP.S247356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293397PMC

Epidemiologically characteristics of human brucellosis and antimicrobial susceptibility pattern of Brucella melitensis in Hinggan League of the Inner Mongolia Autonomous Region, China.

Infect Dis Poverty 2020 Jun 29;9(1):79. Epub 2020 Jun 29.

Hinggan League Center for Disease Control and Prevention, Ulanhot, 137400, China.

Background: Hinggan League is located in the Northeast of the Inner Mongolia Autonomous Region, the historically endemic area of animal and human brucellosis. In this study, the epidemiological characteristics of human brucellosis were analyzed, and the genotypic profile and antimicrobial susceptibilities of Brucella melitensis strains isolated from humans in Hinggan League were investigated.

Methods: The epidemic characteristics were described using case number, constituent ratio, and rate. Read More

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http://dx.doi.org/10.1186/s40249-020-00697-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325291PMC

First Case of Brucella Pneumonia in a Lung Transplant Patient: Case Report and Review of the Literature.

Cureus 2020 Jun 21;12(6):e8733. Epub 2020 Jun 21.

Organ Transplant, King Faisal Specialist Hospital and Research Centre, Riyadh, SAU.

Brucella is one of the most common zoonotic diseases worldwide. It is endemic in the Mediterranean basin. Brucella pneumonia is a rare complication of brucellosis that can present with a variety of clinical and radiological manifestations. Read More

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http://dx.doi.org/10.7759/cureus.8733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308817PMC

Neurobrucellosis Presented by Cerebral Salt Wasting.

Cureus 2020 May 25;12(5):e8275. Epub 2020 May 25.

Internal Disease, Batman District State Hospital, Batman, TUR.

This case reported here was a 27-year-old female patient, and she had no chronic disease other than hypothyroidism. She was brought to the ER with complaints of fever, chills, weakness, and hyponatremia. She has been diagnosed with brucellosis using a serum tube agglutination test (STAT). Read More

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http://dx.doi.org/10.7759/cureus.8275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314369PMC

, a latent "travel bacterium", continual spread and expansion from Northern to Southern China and its relationship to worldwide lineages.

Emerg Microbes Infect 2020 Jun 27:1-28. Epub 2020 Jun 27.

Sanya People 's Hospital, Sanya 572000, Hainan, China.

Brucellosis caused by is considered to be one of the most important zoonotic diseases in China, posing a serious public health problem. Conventional bio-typing, MLVA (multiple locus variable-number tandem repeat analysis), and WGS (whole-genome sequencing)-SNP (single nucleotide polymorphism) were used to study the genetic similarity of in northern and southern China and analyze its relationship with worldwide lineages. The distribution of species/biovars of has obviously changed, and has become the dominant species in southern regions of China. Read More

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http://dx.doi.org/10.1080/22221751.2020.1788995DOI Listing

Nanoparticle-Based Vaccines for Brucellosis: Calcium Phosphate Nanoparticles-Adsorbed Antigens Induce Cross Protective Response in Mice.

Int J Nanomedicine 2020 29;15:3877-3886. Epub 2020 May 29.

Department of Molecular Biology, Pasteur Institute of Iran, Tehran, Iran.

Introduction: Vaccine formulation with appropriate adjuvants is an attractive approach to develop protective immunity against pathogens. Calcium phosphate nanoparticles (CaPNs) are considered as ideal adjuvants and delivery systems because of their great potential for enhancing immune responses. In the current study, we have designed nanoparticle-based vaccine candidates to induce immune responses and protection against and . Read More

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http://dx.doi.org/10.2147/IJN.S249942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269176PMC

Brucellosis underreporting in Greece: assessment based on aggregated laborato-ry data of culture-confirmed cases from public hospitals.

Hippokratia 2019 Jul-Sep;23(3):106-110

Zoonoses Unit, Hellenic National Public Health Organization, Athens, Greece.

Background: spp. isolation is one of the mainstays of brucellosis diagnosis. Simultaneously, the true brucellosis disease rate may be underrepresented in notification systems. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307503PMC

MLVA-16 Genotyping of and Isolates from Different Animal Species in Egypt: Geographical Relatedness and the Mediterranean Lineage.

Pathogens 2020 Jun 22;9(6). Epub 2020 Jun 22.

Friedrich-Loeffler-Institut, Institute of Bacterial Infections and Zoonoses, Naumburger Str. 96a, 07743 Jena, Germany.

Brucellosis is a common zoonotic disease in Egypt. However, there are limited data available on the genetic diversity of brucellae circulating in Egypt and other Mediterranean areas. One hundred and nine (. Read More

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http://dx.doi.org/10.3390/pathogens9060498DOI Listing

A retrospective sero-epidemiological survey of bovine brucellosis on commercial and communal farming systems in Namibia from 2004 to 2018.

Trop Anim Health Prod 2020 Jun 23. Epub 2020 Jun 23.

Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110, South Africa.

Cattle production is the major livestock production activity and the mainstay of Namibia's economy. Sustained beef exports are contingent on a sound sanitary environment where diseases such as brucellosis are under control. In this retrospective study, 49,718 bovine brucellosis testing results from 2004 to 2018 were analyzed to determine the proportion of sero-positive cattle and herds, and the spatial distribution of positive reactors from commercial and communal areas. Read More

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http://dx.doi.org/10.1007/s11250-020-02332-4DOI Listing

Validation of real-time PCR technique for detection of Mycobacterium bovis and Brucella abortus in bovine raw milk.

Braz J Microbiol 2020 Jun 22. Epub 2020 Jun 22.

Universidade Federal de Viçosa, Departamento de Veterinária, Campus Universitário, Viçosa, MG, 36570900, Brazil.

Brucellosis and tuberculosis are diseases of great economic impact in cattle herds and are controlled by governmental programs in many countries. The validation of a diagnostic technique is fundamental for its application in official control programs of these diseases. The aim of the present study was to validate a polymerase chain reaction in real time (qPCR) for detection of Mycobacterium bovis and Brucella abortus in samples of artificially contaminated raw milk. Read More

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http://dx.doi.org/10.1007/s42770-020-00319-9DOI Listing

Molecular characterization of Brucella species detected in humans and domestic ruminants of pastoral areas in Kagera ecosystem, Tanzania.

Vet Med Sci 2020 Jun 21. Epub 2020 Jun 21.

College of Veterinary Medicine and Biomedical Sciences, Department of Veterinary Medicine and Public Health, Sokoine University of Agriculture, Morogoro, Tanzania.

Brucellosis is a zoonotic disease of importance to both public health and the livestock industry. The disease is likely to be endemic in Tanzania and little is reported on molecular characterization of Brucella species in pastoral settings. This study aimed at characterizing Brucella species (targeting genus Brucella) infecting humans, cattle and goat in Kagera region (Ngara and Karagwe districts) using real-time PCR, PCR amplification of 16S rRNA genes and Sanger sequencing. Read More

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http://dx.doi.org/10.1002/vms3.298DOI Listing

[Spatial-temporal distribution of human brucellosis and its correlation with the number of livestock in Ningxia Hui Autonomous Region, 2012-2018].

Zhonghua Liu Xing Bing Xue Za Zhi 2020 Jun;41(6):872-876

Medical Records Statistics Department of Ningxia Hui Autonomous Region People's Hospital, Yinchuan 750004, China.

To analyze the spatial-temporal distribution characteristics of human brucellosis (HB) in Ningxia Hui Autonomous Region (Ningxia) from 2012 to 2018 and the correlation between HB and the number of livestock stocks, so as to provide reference for the development of preventive measures. Data on the incidence of HB was collected from the Infectious Disease Report Information Management System of Ningxia, 2012 to 2018. Data related to HB incidence in Ningxia from 2012 to 2018 was then analyzed by global spatial autocorrelation and local spatial autocorrelation analysis methods through the geographic information system (GIS). Read More

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http://dx.doi.org/10.3760/cma.j.cn112338-20190925-00701DOI Listing

A safe non-toxic Brucella abortus ghosts induce immune responses and confer protection in BALB/c mice.

Mol Immunol 2020 Jun 16;124:117-124. Epub 2020 Jun 16.

College of Animal Science and Technology, Shihezi University, Shihezi 832003, Xinjiang Province, People's Republic of China. Electronic address:

Brucellosis, which is caused by Brucella spp., is an important zoonotic infectious disease that can cause great hazard to public health and safety. However, the current vaccines have several drawbacks, including residual virulence for animals and humans. Read More

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http://dx.doi.org/10.1016/j.molimm.2020.06.002DOI Listing
June 2020
2.973 Impact Factor

Brucellar reproductive system injury: A retrospective study of 22 cases and review of the literature.

J Int Med Res 2020 Jun;48(6):300060520924548

Department of Infection Disease Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.

Objective: We aimed to describe the clinical characteristics and prognosis of 22 patients with -induced reproductive system injury.

Methods: We assessed 22 patients with reproductive system injury between 2010 and 2018 at The First Affiliated Hospital of Xinjiang Medical University.

Results: The disease is predominant in men. Read More

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http://dx.doi.org/10.1177/0300060520924548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303501PMC

Brucella Endocarditis of the Native Mitral Valve Treated With Antibiotics.

Cureus 2020 May 17;12(5):e8167. Epub 2020 May 17.

Internal Medicine, The Wright Center for Graduate Medical Education, Scranton, USA.

Brucellosis is a rare zoonotic infection with a low annual incidence in the United States. Infective endocarditis secondary to brucellosis involving native or prosthetic valves is contemplated to be an extremely rare entity. As can present with non-specific sign and symptoms, clinicians need to have a higher degree of suspicion of endocarditis in culture-negative endocarditis patients, particularly those who have a history of exposure to farm animals. Read More

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http://dx.doi.org/10.7759/cureus.8167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296878PMC

Brucellosis: An Elusive Backyard Agent.

Cureus 2020 May 16;12(5):e8154. Epub 2020 May 16.

Medicine, Shifa International Hospital, Islamabad, PAK.

Brucellosis is a form of zoonotic infection caused by various organisms. It most commonly presents as a case of pyrexia of unknown origin, alongside symptoms such as night sweats, malaise, arthralgias, and myalgias. This report describes the case of a man who presented with pyrexia of unknown origin for one month; he was diagnosed to be a case of brucellosis after enteric fever was ruled out. Read More

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http://dx.doi.org/10.7759/cureus.8154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295138PMC

What is beyond testicular torsion and epididymitis? Rare differential diagnoses of acute scrotal pain in adults: A systematic review.

Ann Med Surg (Lond) 2020 Jul 29;55:265-274. Epub 2020 May 29.

Department of Urology, University Hospital Leipzig, Germany.

Background: Acute scrotal pain is a urological emergency. While for testicular torsion and acute epididymitis clinical recommendations are well established, few is known about low incidence causes of acute scrotal pain. Our aim is to identify and characterise rare differential diagnoses of acute scrotal pain in order to give diagnostic and therapeutic recommendations. Read More

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http://dx.doi.org/10.1016/j.amsu.2020.05.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283975PMC

Immunoproteomics of Brucella abortus reveals potential of recombinant antigens for discriminating vaccinated from naturally infected cattle.

Microb Pathog 2020 Jun 13;147:104345. Epub 2020 Jun 13.

Departamento de Medicina Veterinária Preventiva, Escola de Veterinária, Universidade Federal de Minas Gerais, Avenida Antônio Carlos, 6627. Pampulha, CEP 31270-901, Belo Horizonte, Minas Gerais, Brazil. Electronic address:

Brucellosis serodiagnosis is still a challenge and vaccination is the main measure used to control bovine brucellosis, being S19 and RB51 the most currently used vaccines. So, in order to contribute to brucellosis control, a bidimensional (2D) immunoblot-based approach was used to find immunogenic proteins to be used in serodiagnosis, particularly with ability to be employed in DIVA (Differentiating Infected from Vaccinated Animals) strategy. Immunoproteomic profile of Brucella abortus 2308 was analyzed in 2D western blotting using pooled sera from S19 vaccinated animals, RB51 vaccinated animals, B. Read More

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http://dx.doi.org/10.1016/j.micpath.2020.104345DOI Listing

Evaluating the efficiency of TaqMan real-time PCR and serological methods in the detection of Brucella spp. in clinical specimens collected from suspected patients in Ardabil, Iran.

J Microbiol Methods 2020 Jun 13;175:105982. Epub 2020 Jun 13.

Department of Microbiology, School of Medicine, Ardabil University of Medical Science, Ardabil, Iran. Electronic address:

Background: This study aims to evaluate the efficiency of the TaqMan real-time PCR and serological methods in detecting Brucella spp. in clinical specimens that have been collected from suspected patients in Ardabil, Iran.

Methods: In this cross-sectional study, a total of 113 consecutive patients suspected of brucellosis who were referred to the three hospitals in Ardabil province were selected. Read More

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http://dx.doi.org/10.1016/j.mimet.2020.105982DOI Listing
June 2020
2.026 Impact Factor

Combined Nucleic Acid Assays for Diagnosis of A19 Vaccine-Caused Human Brucellosis.

Transbound Emerg Dis 2020 Jun 16. Epub 2020 Jun 16.

Key Laboratory of Livestock Infectious Diseases in Northeast China, Ministry of Education, Shenyang Agricultural University. Liaoning Province, Shenyang, 110866, P. R. China.

Brucellosis is a common zoonotic disease caused by Brucella and is an epidemic worldwide. Currently, the most effective way to prevent and control the disease in animals is to use live, attenuated vaccines A19 strain. In China, the live attenuated Brucella abortus vaccine is widely used in animal immunization. Read More

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http://dx.doi.org/10.1111/tbed.13685DOI Listing

Seroprevalence of brucellosis and associated risk factors among abattoir workers in Bauchi State, Nigeria.

Pan Afr Med J 2020 7;35:33. Epub 2020 Feb 7.

Nigeria Field Epidemiology and Laboratory Training Programme (NFELTP), Abuja, Nigeria.

Introduction: Brucellosis is a reemerging and neglected zoonotic disease. It is an occupational bio-hazard and a public health problem. The objective of the study was to determine the seroprevalence of brucellosis and its risk factors among abattoir workers in Bauchi state. Read More

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http://dx.doi.org/10.11604/pamj.2020.35.33.18134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247907PMC
February 2020

Molecular docking and in-vitro analysis of Fagonia cretica and Berberis lyceum extract against Brucella melitensis.

Curr Comput Aided Drug Des 2020 Jun 12. Epub 2020 Jun 12.

Department of Zoology Abdul Wali Khan University Mardan. Pakistan.

Background: Brucellosis is an economically important zoonotic disease caused by the gram negative bacteria belonging to the genus Brucella. Medicinal plants are well known for a wide variety of potential antimicrobial agents that can be used as anti-microbial drugs.

Method: In the present study, crude ethanol and methanol extracts of local plants (Berberies lyceum and Fagonia cretica) were tested in vitro against Brucella melitensis via well diffusion method for their antibacterial activity. Read More

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http://dx.doi.org/10.2174/1573409916666200612145712DOI Listing

Minimally Invasive Surgery Oblique Lumbar Interbody Debridement and Fusion for the Treatment of Lumbar Spondylodiscitis.

Orthop Surg 2020 Jun 10. Epub 2020 Jun 10.

Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Objective: To evaluate the efficacy and feasibility of minimally invasive oblique lumbar interbody debridement and fusion for the treatment of conservatively ineffective lumbar spondylodiscitis.

Methods: This is a retrospective study. Between December 2016 and November 2017, a total of 14 consecutive patients (eight males and six females, with an average age of 49. Read More

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http://dx.doi.org/10.1111/os.12711DOI Listing

Shedding of Brucella melitensis happens through milk macrophages in the murine model of infection.

Sci Rep 2020 Jun 10;10(1):9421. Epub 2020 Jun 10.

German Federal Institute for Risk Assessment, Diedersdorfer Weg 1, 12277, Berlin, Germany.

Although shedding of zoonotic brucellae in milk has been demonstrated in natural hosts, these data are still missing for the standard murine infection model. We therefore analysed shedding kinetics and the niche of B. melitensis in murine milk. Read More

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http://dx.doi.org/10.1038/s41598-020-65760-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287137PMC

Use of touch-down polymerase chain reaction to enhance the sensitivity of detection in raw milk.

Anim Biotechnol 2020 Jun 10:1-6. Epub 2020 Jun 10.

Faculty of Veterinary Medicine, Department of Microbiology, Lorestan University, Lorestan, Iran.

Brucellosis is a highly contagious bacterial zoonotic infectious disease severely affecting the public health and economic features of endemic and non-endemic countries. The present study assessed the potentials of using the touch-down polymerase chain reaction (TD-PCR) compared to the conventional PCR and culture methods in order to detect in raw milk samples of 55 sheep and 45 goats through deriving the primers from the element of the genome. In addition, nine isolates of were identified using the culture method. Read More

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http://dx.doi.org/10.1080/10495398.2020.1777149DOI Listing

A case of glomerulonephritis caused by brucellosis.

Authors:
Emine Parlak

Trop Doct 2020 Jun 6:49475520929505. Epub 2020 Jun 6.

Department of Infectious Diseases and Clinical Microbiology, Atatürk University Faculty of Medicine, Erzurum, Turkey.

Brucellosis is the most common zoonosis in the world. It can affect several organs or systems, of which the genitourinary is the second most common after the musculoskeletal. Renal involvement in brucellosis takes the form of IgA nephropathy, interstitial nephritis, pyelonephritis, mixed cryoglobulinemia and kidney failure. Read More

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http://dx.doi.org/10.1177/0049475520929505DOI Listing

Effect of student's empowerment program on brucellosis prevention: an application of extended health belief model.

J Prev Med Hyg 2020 Mar 2;61(1):E25-E30. Epub 2020 Apr 2.

Department of Public Health, Maragheh University of Medical Sciences, Maragheh, Iran.

Background: To determine the effect of student's empowerment program using the extended health belief model on the brucellosis prevention in rural high school in Divandarreh, Kurdistan province, Iran.

Materials And Methods: Quasi-experimental study with repeated measure (pre-test, post-test and at 2-month follow-up). In all 220 rural high school students were selected using a cluster sampling method. Read More

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http://dx.doi.org/10.15167/2421-4248/jpmh2020.61.1.1267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225655PMC

Pan-Proteomic Analysis and Elucidation of Protein Abundance among the Closely Related Species, and .

Biomolecules 2020 May 30;10(6). Epub 2020 May 30.

Friedrich-Loeffler-Institute, Institute of Bacterial Infections and Zoonoses, Naumburger Str. 96a, 07743 Jena, Germany.

Brucellosis is a zoonotic infection caused by bacteria of the genus . The species, and , major causative agents of human brucellosis, share remarkably similar genomes, but they differ in their natural hosts, phenotype, antigenic, immunogenic, proteomic and metabolomic properties. In the present study, label-free quantitative proteomic analysis was applied to investigate protein expression level differences. Read More

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http://dx.doi.org/10.3390/biom10060836DOI Listing

Modulatory Effect of Linoleic Acid During 544 Infection in Murine Macrophage RAW264.7 Cells and Murine Model BALB/c Mice.

J Microbiol Biotechnol 2020 May;30(5):642-648

Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.

In this study, we investigated the effects of linoleic acid (LA) treatment on Brucella abortus infection in professional phagocyte RAW264.7 cells, particularly during the pathogens invasion and intracellular growth in these cells, as well as in murine model BALB/c mice focusing on bacterial splenic proliferation and immunoregulatory activities. LA inhibited the growth of in a doseand time-dependent manner. Read More

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http://dx.doi.org/10.4014/jmb.1911.11037DOI Listing

A novel recombinant multiepitope protein candidate for the diagnosis of brucellosis: A pilot study.

J Microbiol Methods 2020 Jul 30;174:105964. Epub 2020 May 30.

School of Public Health, Jilin University, Changchun 130021, China.

Brucellosis is a zoonotic disease transmitted to humans from infected animals. As a systemic disease, it can harm any organ or system of the host body. Human brucellosis presents with various clinical symptoms, which makes diagnosis challenging. Read More

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http://dx.doi.org/10.1016/j.mimet.2020.105964DOI Listing

Potential Risk Factors of Brucellosis in Dairy Farmers of Peri-urban Areas of South West Delhi.

Indian J Community Med 2020 Mar;45(Suppl 1):S12-S15

Department of Academics and Research, International Institute of Health Management Research, New Delhi, India.

Background: Brucellosis is a bacterial disease caused by various species, which mainly infect cattle, swine, goats, sheep, and dogs. Humans generally acquire the disease through direct contact with infected animals, by eating or drinking contaminated animal products, or by inhaling airborne agents. The majority of cases are caused by ingesting unpasteurized milk or cheese from infected goats or sheep. Read More

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http://dx.doi.org/10.4103/ijcm.IJCM_361_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232972PMC

Bilateral serous choroidal detachment in brucellosis and its management and outcome: Literature review and case report.

Indian J Ophthalmol 2020 Jun;68(6):1204-1206

Internal Medicine, Manipal Hospitals, Bengaluru, Karnataka, India.

To report an unusual case of a 71-year-old livestock farmer with systemic brucellosis and ocular involvement. Examination showed vitreous haze with bilateral serous choroidal detachment. He was treated with topical antibiotics and corticosteroids, Tab rifampicin 600 mg and doxycycline 100 mg for 6 weeks with visual recovery and complete resolution of serous choroidal detachment in 2 weeks. Read More

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http://dx.doi.org/10.4103/ijo.IJO_1418_19DOI Listing