13,914 results match your criteria Brucellosis


Brucellar epididymo-orchitis: a retrospective study of 25 cases.

Aging Male 2019 Feb 15:1-4. Epub 2019 Feb 15.

b Department of Infectious Diseases and Clinical Microbiology , Siirt State Hospital , Siirt , Turkey.

Objective: Brucellosis is a multisystemic disease which may affect all organs. Epididymo-orchitis is the most common form of genitourinary involvement. The aim of this study was to present our eight-year experience regarding the management of patients with brucellar epididymo-orchitis (BEO). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/13685538.2019.1573892DOI Listing
February 2019

Emergency response to occupational brucellosis in a pharmaceutical manufacturing enterprise.

Authors:
Go J Yoshida

J Occup Health 2019 Feb 14. Epub 2019 Feb 14.

Department of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/1348-9585.12015DOI Listing
February 2019

Current status and future recommendations for feral swine disease surveillance in the United States.

J Anim Sci 2019 Feb 5. Epub 2019 Feb 5.

Department of Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.

USDA APHIS Wildlife Services (WS) responded to the recognized threat of feral swine as a pathogen reservoir as early as 2004 through opportunistic sampling of animals harvested by its operational component to curtail swine damage to agriculture and property. Initially, pseudorabies and swine brucellosis were of most concern, as both serve as a potential threat to the domestic swine industry and the latter also possesses zoonotic implications. In 2006, classical swine fever, a foreign animal disease (FAD), became the main driver for feral swine pathogen surveillance. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jas/skz054DOI Listing
February 2019

Interferon-γ receptor-1 gene promoter polymorphisms and susceptibility for brucellosis in Makkah region.

Afr Health Sci 2018 Dec;18(4):1157-1165

Department of Medical Microbiology, Faculty of Applied Medical Sciences, Taif University, Turabah, 21995, KSA.

Background: Genetic polymorphisms that affect the production levels of certain cytokines and/or their receptors may determine the risk, severity or protection in some infectious diseases like brucellosis.

Objectives: The aim of this study was to investigate the association of certain known Interferon-γ Receptor-1 (IFN-γ R1) gene promoter polymorphisms and the susceptibility to infection with Brucellosis in Saudi population.

Methods: A cases-control association study was conducted in 69 individuals with human brucellosis and 94 healthy individuals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4314/ahs.v18i4.36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354847PMC
December 2018

The predictive role of haematological parameters in the diagnosis of osteoarticular brucellosis.

Afr Health Sci 2018 Dec;18(4):988-994

Fırat University Medical Faculty Hospital, Department of Infectious Disease, Elazig, 23000, Turkey.

Background: Brucellosis is a zoonosis that affects several systems, especially with the osteoarticular involvement.

Objectives: This study aims to compare the neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), monocyte/lymphocyte ratio (MLR), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), mean platelet volume (MPV) and red blood cell distribution (RDW) in patients with the osteoarticular involvement and those with non-localised brucellosis and evaluate their predictive value for the diagnosis of osteoarticular brucellosis.

Methods: We enrolled 140 patients with brucellosis, 70 with the osteoarticular involvement and 70 without any localised involvement. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4314/ahs.v18i4.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354860PMC
December 2018

In silico design and in vitro development of a highly accurate test to detect Brucella species

Turk J Med Sci 2019 Feb 11;49(1):368-374. Epub 2019 Feb 11.

Background: Conventionalmethods of detecting Brucella spp. suffer from technical and biological complications. Besides, newly characterized species of the genus Brucella could be neglected by previously designed polymerase chain reaction (PCR) tests. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3906/sag-1807-20DOI Listing
February 2019

Sero-diagnosis of brucellosis in sheep and humans in Assiut and El-Minya governorates, Egypt.

Int J Vet Sci Med 2018 9;6(Suppl):S63-S67. Epub 2018 Feb 9.

Department of Theriogenology, Faculty of Veterinary Medicine, Minia University, El Minya, Egypt.

Egypt is an endemic area with brucellosis, so wherever herd problem associated abortion is present, brucellosis should be suspected, and its sero-diagnosis is needed. The present study aimed to estimate the seroprevalence of brucellosis in sheep and their contact humans in Assiut and El-Minya Governorates where a history of abortion in sheep was the chief complaint of the farmers; besides; the appearance of signs of undulant fever among some contact humans. Also, to identify the risk factors for brucellosis seropositivity at human and animal level. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S23144599173010
Publisher Site
http://dx.doi.org/10.1016/j.ijvsm.2018.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161859PMC
February 2018
1 Read

Brucellosis: Evolution and expected comeback.

Int J Vet Sci Med 2018 21;6(Suppl):S31-S35. Epub 2018 Mar 21.

Faculty of Veterinary Medicine, Department of Medicine and Infectious Diseases, Cairo University, Giza, Egypt.

Brucellosis is a serious infectious disease which causes great direct and indirect economic loses for animal holders worldwide such as the reduction of milk and meat production through abortions/culling of positive reactors, the expense of disease control/eradication and farmers compensation. Although the disease was eradicated from most of the industrial countries, it remains one of the most common zoonotic diseases in developing countries being responsible for more than 500,000 new cases yearly. Brucella is considered to be a bioterrorism organism due to its low infectious doses (10-100 bacteria), capability of persistence in the environment, rapid transmission via different routes including aerosols, and finally due to its difficult treatment by antibiotics. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijvsm.2018.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161863PMC

Characterization of circulating miRNA signature in water buffaloes (Bubalus bubalis) during Brucella abortus infection and evaluation as potential biomarkers for non-invasive diagnosis in vaginal fluid.

Sci Rep 2019 Feb 13;9(1):1945. Epub 2019 Feb 13.

Università degli Studi di Milano, Dipartimento di Medicina Veterinaria, Milano, 20133, Italy.

Brucellosis is an infectious disease caused by bacteria from the Brucella genus that can be transmitted to humans through contact with infected animals or contaminated animal products. Brucellosis also causes financial losses in animal production. Ruminants are highly susceptible to brucellosis, and the causative agent water buffaloes (Bubalus bubalis) is Brucella abortus. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-38365-xDOI Listing
February 2019

A Case of Brucellosis with a Rare Complication: Pericarditis.

Eur J Case Rep Intern Med 2017 27;4(1):000471. Epub 2017 Jan 27.

Department of Gastroenterology, Antalya Training and Research Hospital, Antalya, Turkey.

Objectives: To describe brucellosis and its possible complications according to clinical, laboratory and radiological findings.

Methods: We describe a case of pericarditis visualized at transthoracic echocardiography with clinical manifestations.

Results: Clinical manifestations, imaging and laboratory findings provided the correct diagnosis of pericarditis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12890/2016_000471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346919PMC
January 2017

Successful Management of Prosthetic Valve Endocarditis with Antibiotherapy Alone.

Eur J Case Rep Intern Med 2018 24;5(4):000808. Epub 2018 Apr 24.

Internal Medicine Service, Centro Hospitalar Tondela-Viseu, E.P.E. - Viseu, Portugal.

Objectives: To report a case of mechanical aortic prosthesis endocarditis successfully treated with antibiotics alone.Materials and methods: We describe a clinical case and present a review of the literature.

Results: A 60-year-old female farmer with a mechanical aortic prosthetic valve presented with low back pain and fever. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12890/2018_000808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346756PMC

IFN-γ-dependent nitric oxide suppresses Brucella-induced arthritis by inhibition of inflammasome activation.

J Leukoc Biol 2019 Feb 12. Epub 2019 Feb 12.

Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, USA.

Brucellosis, caused by the intracellular bacterial pathogen Brucella, is a globally important zoonotic disease for which arthritis is the most common focal complication in humans. Wild-type mice infected systemically with Brucella typically do not exhibit arthritis, but mice lacking IFN-γ develop arthritis regardless of the route of Brucella infection. Here, we investigated mechanisms by which IFN-γ suppresses Brucella-induced arthritis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/JLB.4MIA1018-409RDOI Listing
February 2019

Clinical and serological approach to patients with brucellosis: A common diagnostic dilemma and a worldwide perspective.

Microb Pathog 2019 Feb 10;129:125-130. Epub 2019 Feb 10.

Isfahan Medical Students Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address:

According to the WHO factsheet, although approximately half a million brucellosis cases are reported annually, the true incidence is always 10-25 times higher than the reported number of cases. Therefore, we face a common yet uncommonly recognized entity of brucellosis, which highlights the importance of providing precise and understandable guidelines for physician to recognize and manage the disease. Up to now, there is no distinct and clear guideline for brucellosis diagnosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.micpath.2019.02.011DOI Listing
February 2019
2 Reads

Characterization and evolution of countries affected by bovine brucellosis (1996 - 2014).

Transbound Emerg Dis 2019 Feb 10. Epub 2019 Feb 10.

Departament de Sanitat i Anatomia Animals, Universitat Autònoma de Barcelona (UAB), 08193, Bellaterra, Barcelona, Spain.

This paper describes the global distribution and temporal evolution of bovine brucellosis due to Brucella abortus during a 19-year period (1996 - 2014) using the information officially reported to the World Organisation for Animal Health (OIE) by veterinary services of 156 countries. Variables that can influence the health status of bovine brucellosis (i.e. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/tbed.13144
Publisher Site
http://dx.doi.org/10.1111/tbed.13144DOI Listing
February 2019
3 Reads

Endocrine modulation of Brucella abortus-infected osteocytes function and osteoclastogenesis via modulation of RANKL/OPG.

Microbes Infect 2019 Feb 5. Epub 2019 Feb 5.

Instituto de Inmunología, Genética y Metabolismo (INIGEM). Universidad de Buenos Aires (UBA). Consejo Nacional de Investigaciones Científicas y técnicas (CONICET). Buenos Aires, Argentina. Electronic address:

Osteoarticular brucellosis is the most frequent complication of active disease. A large amount of cells in bone are osteocytes. Since bone remodeling process is regulated by hormones we sought to study the effect of cortisol and DHEA in B. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.micinf.2019.01.004DOI Listing
February 2019

Differential expression of cytokines in PBMC of Bos indicus and Bos taurus × Bos indicus cattle due to Brucella abortus S19 antigen.

Anim Biotechnol 2019 Feb 5:1-7. Epub 2019 Feb 5.

a Animal Genetics Division , ICAR-National Bureau of Animal Genetic Resources , Karnal , Haryana , India.

Brucellosis is the most dreadful disease among bovines, although breed differences have been observed in prevalence of disease, worldwide. In present study, antibody response and relative expression of proinflammatory cytokines was compared in Bos indicus (zebu) and Bos taurus × Bos indicus (crossbred) cattle vaccinated by live attenuated Brucella abortus S19 antigen. Six female calves (4-6 months age) of both groups were vaccinated with B. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/10495398.2018.1
Publisher Site
http://dx.doi.org/10.1080/10495398.2018.1555167DOI Listing
February 2019
8 Reads

Brucella canis induces canine CD4 T cells multi-cytokine Th1/Th17 production via dendritic cell activation.

Comp Immunol Microbiol Infect Dis 2019 Feb 30;62:68-75. Epub 2018 Nov 30.

Periodontal Biology Laboratory, Faculty of Dentistry, Universidad de Chile, Santiago, Chile; Dentistry Unit, Faculty of Health Sciences, Universidad Autónoma de Chile, Santiago, Chile. Electronic address:

Brucella canis is a small intracellular Gram-negative bacterium that frequently leads to chronic infections highly resistant to antibiotic therapy in dogs. Also, it causes mild human brucellosis compared to other zoonotic Brucella spp. Herein we characterize the cellular immune response elicited by B. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01479571183011
Publisher Site
http://dx.doi.org/10.1016/j.cimid.2018.11.017DOI Listing
February 2019
1 Read

Brucellosis in an adult female from Fate Bell Rock Shelter, Lower Pecos, Texas (4000-1300 BP).

Authors:
Christine Jones

Int J Paleopathol 2019 Jan 30;24:252-264. Epub 2019 Jan 30.

Texas A&M University-Central Texas, 1001 Leadership Place, Killeen, TX, 76549, United States. Electronic address:

Objective: This project is a case study discussing the differential diagnosis of multiple osteolytic vertebral lesions typical of brucellosis from an adult female from Fate Bell Rock Shelter in the Lower Pecos, Texas (4000-1300 BP).

Materials: One middle to late adult female with exceptional preservation of the vertebrae.

Methods: All skeletal remains were observed with low power magnification and the vertebrae were examined in greater detail using computed tomography (CT). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpp.2019.01.005DOI Listing
January 2019
1 Read

A comparison between adjuvant and delivering functions of calcium phosphate, aluminum hydroxide and chitosan nanoparticles, using a model protein of Brucella melitensis Omp31.

Immunol Lett 2019 Jan 29;207:28-35. Epub 2019 Jan 29.

Nanomedicine and Nanobiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Medical Physics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Vaccination is the most efficient and economic approach used to hinder infection and intense consequences caused by viruses, bacteria, or other pathogenic organisms. Since the intrinsic immunogenicity of recombinant antigens is usually low, safe and potent vaccine adjuvants are needed to ensure the success of those recombinant vaccines. Nanoparticles (NPs) have attracted much interest as adjuvants and delivery systems. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.imlet.2019.01.010DOI Listing
January 2019

Simultaneous breast and pacemaker infection.

IDCases 2019 9;15:e00485. Epub 2019 Jan 9.

Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

Infection with spp. is endemic to the Middle East and the eastern Mediterranean basin. Brucellosis can mimic infectious and non-infectious febrile illnesses and therefore it can pose a diagnostic challenge. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.idcr.2019.e00485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348196PMC
January 2019
1 Read

Molecular Diagnostic Methods of Brucellosis: a Note on Pitfalls.

Iran J Pathol 2018 17;13(2):294-295. Epub 2018 Jul 17.

Dept, of Molecular Biology, Research Center of Health Reference Laboratory, Ministry of Health and Medical Education, Tehran, Iran.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339499PMC
July 2018
3 Reads

Aetiology of livestock fetal mortality in Mazandaran province, Iran.

PeerJ 2019 18;6:e5920. Epub 2019 Jan 18.

Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Mazandaran, Iran.

In the farming industry, the productivity of livestock herds depends on the fertility efficiency of animals. The accurate diagnosis of a broad range of aetiological agents causing fetal death is often difficult. Our aim was to assess the prevalence rates of , , and spp. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7717/peerj.5920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340351PMC
January 2019
1 Read

Human Brucellosis in Israel - The Saga Continues.

Authors:
Daniel Glikman

Isr Med Assoc J 2019 Jan;21(1):52-53

Infectious Diseases Unit, Padeh Poria Medical Center, Poria, and Azrieli Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel.

View Article

Download full-text PDF

Source
January 2019
1 Read

Reemergence of Human Brucellosis in Israel.

Isr Med Assoc J 2019 Jan;21(1):10-12

Infectious Diseases Institute, Rambam Health Care Campus, Haifa, Israel.

Background: The epidemiology of human brucellosis (HB) continues to evolve.

Objectives: To describe the current epidemiology of HB in Israel in general and in the population at risk.

Methods: We calculated the incidence of HB in Israel for the period 2009-2015, overall and for the Arab population. Read More

View Article

Download full-text PDF

Source
January 2019
1 Read

Seroprevalence in a High-Risk Population in Greece: A Cross-Sectional Study.

Interdiscip Perspect Infect Dis 2018 25;2018:8751921. Epub 2018 Dec 25.

Laboratory of Epidemiology and Prevention of Hemoglobinopathies, Acute and Chronic Diseases, Department of Nursing, University of Peloponnese, Valioti & Plateon, 23100 Sparta, Laconia, Greece.

Introduction: Brucellosis is a zoonosis with high occupational risk. However, seroprevalence of antibodies among occupational groups is not known, since studies in endemic countries are rare.

Methods: A cross-sectional seroprevalence study was conducted among livestock farmers in an endemic region in Greece. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2018/8751921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323493PMC
December 2018
1 Read

Protective efficacy of an inactivated vaccine candidate lysed by GI24 against brucellosis in Korean black goats.

Can J Vet Res 2019 Jan;83(1):68-74

Veterinary Public Health, College of Veterinary Medicine, Chonbuk National University, Gobong-ro 79, Iksan, Jeollabuk-do, Republic of Korea (Kim, Moon, Cho, Ochirkhuyag, Hur); Veterinary Histology, College of Veterinary Medicine, Chonbuk National University, Gobong-ro 79, Iksan, Jeollabuk-do, Republic of Korea (Akanda, Park).

The efficacy of GI24-lysed cells as a vaccine candidate against brucellosis in goats was evaluated on 2 groups of Korean black goats. Group A goats were immunized subcutaneously (SC) with sterile phosphate-buffered saline, whereas group B goats were immunized SC with approximately 3 × 10 lysed cells. Subcutaneous immunization with the lysed cells did not cause any negative impact on the overall clinical status, such as behavior and appetite, throughout the study period. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318821PMC
January 2019

Persistent febrile illnesses in Nepal: A systematic review.

Indian J Med Res 2018 Oct;148(4):385-395

Epidemiology and Control of Neglected Tropical Diseases Unit, Institute of Tropical Medicine, Antwerp, Belgium.

Background & Objectives: Although febrile illnesses are a frequent cause of consultation and hospitalization in low- and middle-income countries (LMICs), research has mainly focused on acute febrile illnesses (AFIs). In contrast, there are limited data on the causes of persistent febrile illnesses (PFIs) in LMIC. Lack of clarity on the differential diagnosis of PFIs in the rural tropics leads to the absence of diagnostic guidance tools. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/ijmr.IJMR_505_18DOI Listing
October 2018
1 Read
1.661 Impact Factor

First report of caprine abortions due to Chlamydia abortus in Argentina.

Vet Med Sci 2019 Jan 21. Epub 2019 Jan 21.

Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, CEDIVE, La Plata, Argentina.

Infectious abortions of goats in Argentina are mainly associated with brucellosis and toxoplasmosis. In this paper, we describe an abortion outbreak in goats caused by Chlamydia abortus. Seventy out of 400 goats aborted. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/vms3.145DOI Listing
January 2019
2 Reads

Identification of Hemolysine Genes and their Association with Antimicrobial Resistance Pattern among Clinical Isolates of in West of Iran.

Adv Biomed Res 2018 19;7:153. Epub 2018 Dec 19.

Department of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Background: is expressing a broad range of different hemolysins enhancing its ability to establish and maintain infection in humans. The aim of this study was to identify the types of hemolysins in different clinical isolates of and their association with antibiotic resistance patterns.

Materials And Methods: In this cross-sectional and descriptive study, clinical isolates of were collected from Hamedan's hospitals during an 11-month period from June 2016 to January 2017 and identified by using biochemical tests. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/abr.abr_143_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319038PMC
December 2018
1 Read

Partial protection induced by Salmonella based Brucella vaccine candidate in pregnant guinea pigs.

Vaccine 2019 Feb 17;37(7):899-902. Epub 2019 Jan 17.

College of Veterinary Medicine, Chonbuk National University, Iksan Campus, 570-752 Iksan, Republic of Korea. Electronic address:

Residual virulence is a major drawback in current Brucella vaccines. Live vaccines induce abortions in pregnant animals. Hence, a novel anti-Brucella vaccine was developed utilizing rough Salmonella delivering four Brucella antigens. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vaccine.2019.01.020DOI Listing
February 2019
3 Reads

A systematic review and meta-analysis of the prevalence of osteoarticular brucellosis.

PLoS Negl Trop Dis 2019 01 18;13(1):e0007112. Epub 2019 Jan 18.

Department of Veterinary Pathobiology, Texas A&M University, College Station, Texas, United States of America.

Background: Infection of bones and joints remains one of the most commonly described complications of brucellosis in humans and is predominantly reported in all ages and sexes in high-risk regions, such as the Middle East, Asia, South and Central America, and Africa. We aimed to systematically review the literature and perform a meta-analysis to estimate the global prevalence of osteoarticular brucellosis (OAB).

Methodology: Major bibliographic databases were searched using keywords and suitable combinations. Read More

View Article

Download full-text PDF

Source
http://dx.plos.org/10.1371/journal.pntd.0007112
Publisher Site
http://dx.doi.org/10.1371/journal.pntd.0007112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355028PMC
January 2019
17 Reads

Development of an auxotrophic, live-attenuated Brucella suis vaccine strain capable of expressing multimeric GnRH.

Vaccine 2019 Feb 14;37(7):910-914. Epub 2019 Jan 14.

Center for One Health Research, Virginia Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061, USA. Electronic address:

Feral swine cost around $1.5 billion each year in agricultural, environmental, and personal property damages. They are also the most widespread carriers of the zoonotic disease brucellosis, which threatens both livestock bio-security and public health. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vaccine.2018.12.070DOI Listing
February 2019
2 Reads

Correction: Clinical features of 2041 human brucellosis cases in China.

Authors:

PLoS One 2019 16;14(1):e0211102. Epub 2019 Jan 16.

[This corrects the article DOI: 10.1371/journal.pone. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211102PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334912PMC
January 2019

Complete Genome Sequence of Brucella canis GB1, a Strain Isolated from a Poodle in Beijing, China.

Microbiol Resour Announc 2019 Jan 10;8(2). Epub 2019 Jan 10.

National Reference Laboratory for Animal Brucellosis, China Institute of Veterinary Drug Control, Beijing, China.

Brucella spp. are facultative intracellular pathogens and zoonotic agents which pose a great threat to human health. Twelve different Brucella species have been identified to date. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MRA.01476-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328664PMC
January 2019
2 Reads

Newcastle disease virus-like particles containing the Brucella BCSP31 protein induce dendritic cell activation and protect mice against virulent Brucella challenge.

Vet Microbiol 2019 Feb 11;229:39-47. Epub 2018 Dec 11.

Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences / Key Laboratory for Veterinary Bio-Product Engineering, Ministry of Agriculture, Nanjing 210014, China. Electronic address:

Brucellosis is a widespread zoonosis that poses a substantial threat to human and animal public health due to the absence of a sufficiently safe and efficient vaccine. Virus-like particles (VLPs) have been developed as novel vaccine candidates and suitable carrier platforms for the delivery of exogenous proteins. Herein, we constructed chimeric virus-like particles (cVLPs) assembled by a Newcastle disease virus (NDV) M protein and glycosylphosphatidylinositol-anchored Brucella BCSP31 protein (GPI-BCSP31). Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03781135183100
Publisher Site
http://dx.doi.org/10.1016/j.vetmic.2018.12.007DOI Listing
February 2019
7 Reads

Detection of Brucella abortus by a platform functionalized with protein A and specific antibodies IgG.

Microsc Res Tech 2019 Jan 14. Epub 2019 Jan 14.

Departamento de Inmunología. Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, México City, Mexico.

Oriented immobilization of antibodies on a sensor surface is critical for enhancing both the antigen-binding capacity and the sensitivity of immunosensors. In this study, we describe a strategy to adsorb immunoglobulin G (IgG) anti-Brucella antibodies onto a silicon surface, oriented by protein A obtained from Staphylococcus aureus (SpA). X-ray photoelectron spectroscopy and atomic force microscopy were used to characterize topographically, morphologically, and chemical changes of the sensor functionalization. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jemt.23206DOI Listing
January 2019
2 Reads

Detection of Brucella spp. in dogs at Pantanal wetlands.

Braz J Microbiol 2019 Jan 10;50(1):307-312. Epub 2018 Dec 10.

Universidade Católica Dom Bosco (UCDB), Av. Tamandaré, 6000, Jardim Seminário, Campo Grande, Mato Grosso do Sul, CEP: 79117-900, Brazil.

Canine brucellosis is an infectious disease that produces reproductive disease in both males and females. Although Brucella canis is more common, the infection by Brucella abortus is more frequent in dogs sharing habitats with livestock and wild animals. We decided to investigate the role of dogs in the maintenance of Brucella spp. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s42770-018-0006-5DOI Listing
January 2019
1 Read

Seroprevalence Of Brucellosis Among Patients Presenting With Non - Specific Symptoms At Ayub Teaching Hospital Abbottabad.

J Ayub Med Coll Abbottabad 2018 Oct-Dec;30(4):566-570

Department of Medicine, Ayub Teaching Hospital, Abbottabad, Department of Community Medicine, Ayub Medical College, Abbottabad, Pakistan.

Background: Brucellosis is one of the prevalent zoonotic diseases worldwide. It not only adds to the global burden of disease but also has huge economic impact. Clinical features of human brucellosis are usually vague. Read More

View Article

Download full-text PDF

Source
January 2019
6 Reads

The Pattern of Tpeak-Tend Interval and QTdis, and Pdis in Children with Brucellosis.

J Trop Pediatr 2019 Jan 8. Epub 2019 Jan 8.

Department of Pediatrics, Van Yuzuncu Yil Universitiy, Van 65090, Turkey.

Objective: To investigate the effect of inflammation on the conducting system of the heart in patients diagnosed with brucellosis.

Methods: A total of 42 patients diagnosed with brucellosis and 39 age and sex-matched healthy children were enrolled into the study. Pre- and post-treatment electrocardiographic parameters in brucellosis and control group were recorded from an electrocardiogram for each patient. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/tropej/fmy078DOI Listing
January 2019
2 Reads

Persistence of in the Bone Marrow of Infected Mice.

J Immunol Res 2018 3;2018:5370414. Epub 2018 Dec 3.

Programa de Investigación en Enfermedades Tropicales, Escuela de Medicina Veterinaria, Universidad Nacional, Heredia, Costa Rica.

Brucellosis is a zoonotic bacterial infection that may persist for long periods causing relapses in antibiotic-treated patients. The ability of to develop chronic infections is linked to their capacity to invade and replicate within the mononuclear phagocyte system, including the bone marrow (BM). Persistence of in the BM has been associated with hematological complications such as neutropenia, thrombocytopenia, anemia, and pancytopenia in human patients. Read More

View Article

Download full-text PDF

Source
https://www.hindawi.com/journals/jir/2018/5370414/
Publisher Site
http://dx.doi.org/10.1155/2018/5370414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304906PMC
December 2018
4 Reads

Identification of Cross-Protective Potential Antigens against Pathogenic spp. through Combining Pan-Genome Analysis with Reverse Vaccinology.

J Immunol Res 2018 9;2018:1474517. Epub 2018 Dec 9.

Palestine-Korea Biotechnology Center, Palestine Polytechnic University, Hebron, State of Palestine.

Brucellosis is a zoonotic infectious disease caused by bacteria of the genus . , , and are the most pathogenic species of this genus causing the majority of human and domestic animal brucellosis. There is a need to develop a safe and potent subunit vaccine to overcome the serious drawbacks of the live attenuated vaccines. Read More

View Article

Download full-text PDF

Source
https://www.hindawi.com/journals/jir/2018/1474517/
Publisher Site
http://dx.doi.org/10.1155/2018/1474517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304850PMC
December 2018
9 Reads

Correction to: Brucellosis seroprevalence in ovine and caprine flocks in China during 2000-2018: a systematic review and meta-analysis.

BMC Vet Res 2019 01 8;15(1):18. Epub 2019 Jan 8.

College of Animal Science & Veterinary Medicine, Heilongjiang Bayi Agricultural University, No.5, XinFeng Rd., Saertu District, Daqing City, 163319, Heilongjiang Province, China.

The original article [1] contained a minor error whereby Table 1 was typeset incorrectly. Read More

View Article

Download full-text PDF

Source
https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-
Publisher Site
http://dx.doi.org/10.1186/s12917-018-1749-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323784PMC
January 2019
5 Reads

Spontaneous spondylodiscitis: review, incidence, management, and clinical outcome in 44 patients.

Neurosurg Focus 2019 Jan;46(1):E10

2Neurosurgery Department, Cairo University, Cairo, Egypt.

OBJECTIVESpontaneous spondylodiscitis remains uncommon but is a serious complication of the vertebral column. Risk factors include diabetes, hemodialysis, intravenous drug abuse, and chronic steroid use, and pain is the most common presenting symptom. This study aims to review the literature and report on the incidence, management, and clinical outcome of spontaneous spondylodiscitis in 44 patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3171/2018.10.FOCUS18463DOI Listing
January 2019
4 Reads
2.105 Impact Factor

Development of new generation of vaccines for .

Heliyon 2018 Dec 26;4(12):e01079. Epub 2018 Dec 26.

Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

is a Gram-negative facultative and intracellular bacteria, it causes bovine brucellosis, a zoonotic disease that is responsible for considerable economic loss to owners of domesticated animals and can cause problems in otherwise healthy humans. There are a few available live attenuated vaccines for animal immunization against brucellosis; however, these have significant side effects and offer insufficient protective efficacy. Thus, the need for more research into the Molecular pathobiology and immunological properties of that would lead to the development of better and safer vaccines. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.heliyon.2018.e01079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307385PMC
December 2018
1 Read

Intranasally administered anti-Brucella subunit vaccine formulation induces protective immune responses against nasal Brucella challenge.

Vet Microbiol 2019 Jan 23;228:112-118. Epub 2018 Nov 23.

College of Veterinary Medicine, Chonbuk National University, Iksan Campus, 570-752, Iksan, Republic of Korea. Electronic address:

The present study was aimed to develop a safe and effective anti-Brucella subunit vaccine for mucosal protection against the respiratory exposure of Brucella infection. A chitosan-based Brucella nasal vaccine (BNV) was formulated using well-known Brucella immunogens, sodC, omp19, BLS and PrpA and tested against nasal Brucella challenge in BALB/c mice. The mice were intra-nasally vaccinated with sterile phosphate buffer saline (PBS), BNV or BNV plus Brucella LPS, and humoral (systemic IgG and mucosal IgA) and cell-mediated immune responses were analyzed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vetmic.2018.11.022DOI Listing
January 2019

3D structure of a Brucella melitensis porin: molecular modelling in lipid membranes.

J Biomol Struct Dyn 2018 Dec 28:1-13. Epub 2018 Dec 28.

a Laboratoire de Chimie Physique des Biomolécules , Unité de Chimie Physique Théorique et Structurale (UCPTS), University of Namur , Namur , Belgium.

Brucella melitensis is a pathogenic bacterium responsible for brucellosis in mammals and humans. Its outer membrane proteins (Omp) control the diffusion of solutes through the membrane, and they consequently have a crucial role in the design of diagnostics and vaccines. Moreover, such proteins have recently revealed their potential for protein-based biomaterials. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/07391102.2018.1
Publisher Site
http://dx.doi.org/10.1080/07391102.2018.1529627DOI Listing
December 2018
9 Reads

Guanylate-binding protein 5 licenses caspase-11 for Gasdermin-D mediated host resistance to Brucella abortus infection.

PLoS Pathog 2018 12 27;14(12):e1007519. Epub 2018 Dec 27.

Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

Innate immune response against Brucella abortus involves activation of Toll-like receptors (TLRs) and NOD-like receptors (NLRs). Among the NLRs involved in the recognition of B. abortus are NLRP3 and AIM2. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1007519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326519PMC
December 2018
2 Reads

Wildlife Management Practices Associated with Pathogen Exposure in Non-Native Wild Pigs in Florida, U.S.

Viruses 2018 Dec 26;11(1). Epub 2018 Dec 26.

Department of Wildlife Ecology and Conservation, University of Florida, Gainesville, FL 32611, USA.

Land use influences disease emergence by changing the ecological dynamics of humans, wildlife, domestic animals, and pathogens. This is a central tenet of One Health, and one that is gaining momentum in wildlife management decision-making in the United States. Using almost 2000 serological samples collected from non-native wild pigs () throughout Florida (U. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/v11010014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356989PMC
December 2018
1 Read

Reasons behind the epidemiological situation of brucellosis in the Republic of Kazakhstan.

Acta Trop 2019 Mar 21;191:98-107. Epub 2018 Dec 21.

Kazakh national agrarian university, Almaty, Kazakhstan.

Brucellosis is endemic in the Republic of Kazakhstan, particularly in agro-pastoral areas. The purpose of this research is to study the epidemiological situation of brucellosis in livestock recorded in the Republic of Kazakhstan, and to identify the reasons why anti-brucellosis measures were not effective. The research was performed on statistical data provided by the Republican Veterinary Laboratory (RVL), the Ministry of Agriculture of the Republic of Kazakhstan. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0001706X183122
Publisher Site
http://dx.doi.org/10.1016/j.actatropica.2018.12.028DOI Listing
March 2019
8 Reads

Human brucellosis caused by raw dairy products: A review on the occurrence, major risk factors and prevention.

Int J Food Microbiol 2019 Mar 12;292:39-47. Epub 2018 Dec 12.

Animal and Plant Health Agency (APHA), Addlestone, Surrey, United Kingdom.

Despite considerable efforts made to address the issue of brucellosis worldwide, its prevalence in dairy products remains difficult to estimate and represents an important public health issue in many areas of the globe today. This is partly explained by the increasing tendency for consumption of raw dairy products, making the prevention and control of this zoonosis even more critical. This review summarizes reports published since the early 2000s on human brucellosis caused by contaminated dairy products and the systems of evaluation and assessment which are used to improve the diagnosis, surveillance, control and prevention of the disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijfoodmicro.2018.12.009DOI Listing
March 2019
3.082 Impact Factor