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World Neurosurg 2020 Jun 26. Epub 2020 Jun 26.

Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California. 1200 N State Street, Suite 3300 Los Angeles, CA 90033. Electronic address:

Idiopathic spinal cord herniation is a rare cause of progressive myelopathy that can result in severe disability. In the following report, an illustrative case and associated video in the surgical management of ventral thoracic spinal cord herniation is presented and discussed. Spinal cord herniation is most commonly observed in the thoracic spine and is characterized by ventral displacement of the spinal cord through a defect in the dura. Read More

Rev Neurol 2020 Jul;71(1):26-30

Hospital Universitario Donostia, San Sebastián, España.

Introduction: Idiopathic medullary herniation is an infrequent disease, which shows up in clinical form as a progressive mielopathy, most commonly known as the Brown-Sequard syndrome. Its anatomical base is a dural defect where a portion of anterior spinal cord gets progressively incarcerated. The MRI and myelo-CT scan show a bending of the spinal cord in the form of a «bell tent» towards the anterior dural sheath at the mid-dorsal portion mainly. Read More

J Clin Neurosci 2020 Jul 11;77:222-224. Epub 2020 May 11.

Department of Neurology, Rouen University Hospital and University of Rouen, 76031 Rouen Cedex, France. Electronic address:

Fibrocartilaginous embolism (FCE) is a rare and probably under diagnosed cause of spinal cord infarction presumably due to acute embolization of nucleus pulposus fragments into the spinal circulation. Concomitant cerebral involvement is much rarer and often asymptomatic. Although the definitive diagnosis is histologic, certain criteria have been proposed to support the diagnosis in living patients, such as absence of vascular risk factors, acute onset or antecedent of valsalva maneuver before the episode and the exclusion of potential differential diagnoses. Read More

Wien Klin Wochenschr 2020 May 5. Epub 2020 May 5.

Department of Neurology, Municipal Hospital Landshut, Robert-Koch Str. 1, 84034, Landshut, Germany.

Rinsho Shinkeigaku 2020 May 18;60(5):351-357. Epub 2020 Apr 18.

Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University.

The patient was a 40-year-old woman who was previously diagnosed with systemic lupus erythematosus and myasthenia gravis and had received prednisolone and tacrolimus for more than 7 years. In February 2017, she noticed pain in her lower back and weakness of the lower limbs, and was referred to our hospital on day 5. She had shingles in the right lower thoracic dermatomes and Brown-Séquard syndrome with right-sided dominant weakness in her lower limbs and left-sided superficial sensory disturbance below the L1 level. Read More

J Vis Exp 2020 Mar 24(157). Epub 2020 Mar 24.

Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Department of Neurological Surgery and Goodman Campbell Brain and Spine, Indiana University School of Medicine;

Incomplete spinal cord injury (SCI) often leads to impairments of sensorimotor functions and is clinically the most frequent type of SCI. Human Brown-Séquard syndrome is a common type of incomplete SCI caused by a lesion to one half of the spinal cord which results in paralysis and loss of proprioception on the same (or ipsilesional) side as the injury, and loss of pain and temperature sensation on the opposite (or contralesional) side. Adequate methodologies for producing a spinal cord lateral hemisection (HX) and assessing neurological impairments are essential to establish a reliable animal model of Brown-Séquard syndrome. Read More

J Coll Physicians Surg Pak 2020 Mar;30(3):321-323

Department of Rheumatology, Shaikh Zayed Postgraduate Medical Institute, Lahore, Pakistan.

Aquaporin-4 antibodies are hallmark of neuromyelitis optica (NMO) and neuromyelitis optica spectrum disorders (NMOSD) that are distinct disease entities. We report a 24-year male with NMO, who presented with Brown-Sequard syndrome. Clinical and laboratory parameters confirmed the diagnosis of systemic lupus erythematosus (SLE). Read More

BMC Neurol 2019 Dec 12;19(1):321. Epub 2019 Dec 12.

Department of Radiology, the First Hospital of JiLin University, Xinmin St. #71, Changchun, 130021, China.

Background: Spinal cord infarction (SCI) is rarely caused by vertebral artery dissection (VAD), which is an important cause of posterior circulation stroke in young and middle-aged patients. We report the case of a middle-aged patient without obvious risk factors for atherosclerosis who had SCI from right VAD.

Case Presentation: An otherwise healthy 40-year-old man presented with acute right-sided body weakness. Read More

Surg Neurol Int 2019 25;10:210. Epub 2019 Oct 25.

Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran.

Background: Spontaneous spinal epidural hematomas (SEHs) due to the utilization of factor Xa inhibitors are rare.

Case Description: A 66-year-old female presented with a Brown-Sequard syndrome attributed to a cervical epidural hematoma secondary to the utilization of rivaroxaban, one of the factor Xa inhibitors. Following a cervical laminectomy for the evacuation of the hematoma, the patient completely recovered. Read More

Ann Ib Postgrad Med 2019 Jun;17(1):39-44

Department of Neurological Surgery, University College Hospital, Ibadan, Nigeria.

Spinal cord injury is a global problem. It is a devastating life altering condition that is associated with permanent disability and reduced life expectancy. Road traffic accident has been described in global literature as the commonest aetiology and second to it is falls. Read More

Acta Neurochir (Wien) 2020 04 23;162(4):961-965. Epub 2019 Nov 23.

UConn Health Division of Neurosurgery, 263 Farmington Avenue, Farmington, CT, 06030-8073, USA.

Background: Spinal arteriovenous fistula (AVF) represents the most common type of spinal vascular lesions and is often associated with progressive neurological dysfunction.

Method: Here, we present a unique case of a spinal vascular malformation that does not fit the traditional classification schemes. The patient presented with progressive neurologic deficits resembling partial Brown-Sequard syndrome and was subsequently found to have a lesion resembling type I spinal AVF. Read More

Korean J Neurotrauma 2019 Oct 2;15(2):204-208. Epub 2019 Sep 2.

Department of Neurosurgery, Chungdam Wooridul Spine Hospital, Seoul, Korea.

Brown-Séquard syndrome (BSS) is an incomplete spinal cord injury caused by damage to one-half of the spinal cord. Most cases of BSS result from penetrating trauma or tumors, and acute cervical disc herniation is a relatively rare cause of BSS. In this case, a 34-year-old man with a sudden onset posterior neck pain and left side motor weakness was admitted to the local spine hospital. Read More

Case Rep Neurol Med 2019 25;2019:7987038. Epub 2019 Sep 25.

Department of Radiology and Medical Imaging, AHEPA University Hospital, Panepistimioupoli, 54124 Thessaloniki, Greece.

We report the case of a 45-year-old female who presented with acute left abdominal pain and subsequently developed a left partial Brown-Séquard syndrome. Spinal fluid, inflammatory and prothrombotic tests were unremarkable. Magnetic resonance showed a left intraforaminal disc prolapse at the T9-T10 level and a hyperintense lesion on T2-weighted images in the left postero-lateral cord at the T8-T9 level with restricted diffusion on DWI imaging. Read More

Clin Exp Emerg Med 2019 Sep 30;6(3):268-271. Epub 2019 Sep 30.

Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Late-onset Brown-Séquard syndrome (BSS) is a rare condition resulting from a spinal cord injury that develops weeks to years after a blunt trauma. Acute-onset BSS after a blunt injury has been rarely reported. Here, we report on a case of BSS, in a 58-year-old man, that developed immediately after a motor vehicle accident. Read More

J Orthop Case Rep 2019 ;9(2):30-33

Department of Orthopedic, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

Introduction: Intradural disc herniation is a rare disease and it accounts for 0.26-0.30% of all herniated discs. Read More

J Pain Res 2019 31;12:2403-2410. Epub 2019 Jul 31.

Department of Orthopaedics, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu, People's Republic of China.

Objective: To report a rare case of cervical intradural disc herniation (IDH) with Brown-Séquard syndrome and to review the related literature.

Methods: Pathogenesis, preoperative diagnosis, and the surgical technique are discussed, and previous literature reports are reviewed.

Results: A 44-year-old woman complained of weakness of the left upper and lower extremities and paresthesias in the right limbs after a bicycle ride 3 days earlier. Read More

Surg Neurol Int 2019 24;10:56. Epub 2019 Apr 24.

Pars Advanced and Minimally Invasive Medical Manners Research Center, Iran University of Medical Sciences, Tehran, Iran.

Background: Symptomatic T1-T2 disc herniations are rare and, in most cases, are located posterolaterally. Posterior approaches may utilize transfacet pedicle-sparing techniques, while the less frequent central/anterolateral discs may warrant anterior surgery.

Case Description: Here, we reviewed four cases of symptomatic T1-T2 disc herniations; two patients were paraparetic due to central discs and underwent anterior surgery utilizing a cage construct. Read More

J Family Med Prim Care 2019 Jun;8(6):2161-2164

Consultant Neurologist University Hospital of Sharja, Sharja, UAE.

Consequences of varicella zoster infection reflect a wide range of minor to serious complications involving the central nervous system. This is a case series with challenging presentations, imaging features and favorable outcome. For example, the cases presented with clinical features that resemble Brown Sequard Syndrome, transverse myelitis manner and multiple sclerosis and cognitive decline. Read More

World Neurosurg 2019 Sep 21;129:295-297. Epub 2019 Jun 21.

Department of Neurosurgery, Albany Medical Center, Albany, New York, USA.

Background: Direct penetrating trauma to the spinal cord as a result of stabbing is rare. The vertebral column is strongly suited to protecting the vital neural structures underneath, especially in the midline.

Case Description: A 25-year-old woman experienced a direct stabbing injury to her spinal cord, through the midline structures, resulting in bilateral dorsal column injury. Read More

World Neurosurg 2019 Sep 31;129:81-84. Epub 2019 May 31.

Department of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address:

Background: Idiopathic spinal cord herniation is a rare condition that involves spinal cord herniation through a defect in the ventral dura.

Case Description: We present a case of a 61-year-old woman who initially presented in 2016 with an approximately 1-year history of burning right lower extremity pain and gait instability. Her neurologic examination was consistent with thoracic Brown-Sequard syndrome, and spinal magnetic resonance imaging showed a focal defect in the ventral dura at the superior aspect of T4 with the left aspect of the cord herniating into the defect. Read More

Global Spine J 2019 May 8;9(1 Suppl):15S-21S. Epub 2019 May 8.

AOSpine Knowledge Forum Deformity, Davos, Switzerland.

Study Design: Retrospective case study on prospectively collected data.

Objectives: The purpose of this explorative study was: 1) to determine if patterns of spinal cord injury could be detected through intra-operative neuromonitoring (IONM) changes in pediatric patients undergoing spinal deformity corrections, 2) to identify if perfusion based or direct trauma causes of IONM changes could be distinguished, 3) to observe the effects of the interventions performed in response to these events, and 4) to attempt to identify different treatment algorithms for the different causes of IONM alerts.

Methods: Prospectively collected neuromonitoring data in pre-established forms on consecutive pediatric patients undergoing coronal spinal deformity surgery at a single center was reviewed. Read More

BMJ Case Rep 2019 May 21;12(5). Epub 2019 May 21.

Department of Surgery, Neurosurgery Section, Hospital Universitario Fundacion Santa Fe de Bogota, Bogota, Colombia.

Idiopathic Spinal Cord Herniation (ISCH) is considered to be a rare cause of Thoracic Myelopathy. It is secondary to the gliding of the Spinal Cord through an anterior dural defect, without a completely defined cause. We present a case of ISCH which, even though was in its usual location, developed in a woman at a younger age than expected. Read More

Rinsho Shinkeigaku 2019 May 26;59(5):282-285. Epub 2019 Apr 26.

Department of Neurology, Kitano Hospital, The Tazuke Kofukai Medical Research Institute.

A 47-year-old man presented with left shoulder pain and muscle weakness in the left limbs on November 2017. On the next day, he experienced dysesthesia of the right limbs and hypohidrosis of the left limbs and developed thermal hypoalgesia in right side of body and muscle weakness of the left upper and lower limbs progressed. He was diagnosed with acute myelitis and Brown-Séquard syndrome, based on cervical MRI scan. Read More

Ann Clin Lab Sci 2019 Mar;49(2):265-270

Department of Neurosurgery, Jinjiang Municipal Hospital, Jinjiang, Fujian, China.

Background: Spinal neurosyphilis manifesting as a solitary syphilitic gumma is exceedingly rare. There are non-specific imaging findings and challenges in the diagnosis of spinal syphilitic gumma, which could be easily misdiagnosed as tumor lesions and require surgical resection or biopsy.

Clinical Presentation: We report the case of a 45-year-old female patient who was diagnosed with Spinal syphilitic gumma. Read More

Am J Emerg Med 2019 06 27;37(6):1216.e3-1216.e5. Epub 2019 Mar 27.

Stroke Center and Department of Neurology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taiwan; School of Medicine, Tzu Chi University, Hualien, Taiwan. Electronic address:

The frequency of stroke mimics among stroke patients has been reported to be up to 30%, and that in patients who receive thrombolytic therapy ranges between 1% and 16%. Atlantoaxial dislocation with myelopathy mimicking stroke is extremely rare. An 83-year-old man with a history of old cerebellar infarction presented to the emergency department with acute left hemiplegia after a chiropractic manipulation of the neck and back several hours before symptom onset. Read More

J Spinal Cord Med 2019 Mar 14:1-5. Epub 2019 Mar 14.

a Department of Neurology , SCTIMST , Trivandrum , India.

Context: Idiopathic spinal cord herniation (ISCH) remains an obscure, under recognised but potentially treatable entity among the etiologies of compressive myelopathy.

Findings: Here, we present a retrospective case series of eight patients of ISCH with their clinical features, imaging findings and long-term follow up data along with a relevant review of the literature. Mean age at presentation was 36 years with the duration of symptoms ranging from two months to more than thirty years. Read More

World Neurosurg 2019 Jun 6;126:346-353. Epub 2019 Mar 6.

Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore, India.

Background: Idiopathic spinal cord herniation (ISCH) is a treatable spinal disease. It is rare and often misdiagnosed, causing a delay in management. The etiology is multifactorial, with one of the causes being duplication of the ventral dura. Read More

J Clin Immunol 2019 02 22;39(2):171-181. Epub 2019 Jan 22.

Centre de Référence National des Cytopénies Autoimmunes de l'Enfant (CEREVANCE), University Hospital of Bordeaux, Bordeaux, France.

Purpose: Immune thrombocytopenic purpura (ITP) and autoimmune hemolytic anemia (AIHA) are associated in the definition of Evans syndrome (ES). The occurrence of neurological involvement in this population is poorly described and suggests an underlying primary immunodeficiency (PID). We aimed to describe the clinical manifestations, evolution, and PID profiles of these patients. Read More

Neurosurg Rev 2019 Dec 18;42(4):791-798. Epub 2018 Dec 18.

Department of Neurosurgery, University of Utah School of Medicine, Salt Lake City, UT, USA.

Review of the literature with case illustration. Non-missile penetrating spinal injury (NPSI) represents a small subset of spinal cord injuries at tertiary trauma centers and is comprised mostly of knife violence. Strict guidelines for the management of penetrating spinal cord injury remain elusive given the variability of mechanisms, rarity of clinical experience, and paucity of prospective studies. Read More

Trauma Case Rep 2018 Dec 26;18:28-30. Epub 2018 Nov 26.

Gadjah Mada University, Sardjito Hospital, Yogyakarta, Indonesia.

Introduction: Combination between SCIWORA and Brown-Sequard syndrome in a patient is a rare condition. In SCIWORA, there is usually a delay in neurologic deficits which can potentially lead to misdiagnosis. Therefore, the clinician should have a good understanding of the course of the disease to make a good diagnosis and treatment. Read More

Oper Neurosurg (Hagerstown) 2019 07;17(1):21-31

Department of Neurosurgery, Cleveland Clinic, Cleveland, Ohio.

Background: Idiopathic ventral thoracic spinal cord herniation is a rare condition that usually presents with progressive myelopathy or Brown-Séquard syndrome. More than 100 cases have been reported with significant variance in surgical treatment strategies and likewise, significant variance in patient outcomes. Although laminectomy has often been used, to date, there is no consensus regarding the optimal surgical approach or strategy for ventral dural repair. Read More

Surg Neurol Int 2018 23;9:213. Epub 2018 Oct 23.

Department of Neurosurgery, Riverside University Health System, Riverside, California, USA.

Background: Brown-Sequard syndrome (BSS) is a well-known entity that is most commonly caused by a penetrating injury to the spinal cord (e.g., stab wound or gunshot wound). Read More

Medicine (Baltimore) 2018 Sep;97(37):e12377

The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province. P.R. China.

Rationale: Brown-Sequard syndrome (BSS) is manifested as ipsilateral motor deficit and contralateral sensory loss. BSS caused by herniated cervical disc is extremely rare and easily be misdiagnosed, and clinical features of this problem were not fully understood.

Patient Concerns: A 57-year-old man presented with a 3-month history of weakness in his right arm, and he experienced progressive right hemiparesis at 2 days before admission, along with contralateral deficit in sensation of pain and temperature below T2. Read More

Radiographics 2018 Jul-Aug;38(4):1201-1222

From the Department of Radiology, SUNY Downstate Medical Center, University Hospital of Brooklyn, 450 Clarkson Ave, Brooklyn, NY 11203 (V.K.K., V.V., Z.A.C., D.L.R.); Department of Radiology, University of California Davis Health System, Sacramento, Calif (M.B.); and Department of Radiology, University of Iowa Hospital and Clinics, Iowa City, Iowa (W.R.K.S.).

The ability to localize the three spinal tracts (corticospinal tract, spinothalamic tract, and dorsal [posterior] columns) involved in incomplete spinal cord syndromes at cross-sectional imaging and knowledge of the classic clinical manifestations of the various syndromes enable optimized imaging evaluation and provide clinicians with information that aids in diagnosis and treatment. The requisite knowledge for localizing these tracts is outlined. The authors review the spinal cord anatomy, blood supply, and course of these tracts and describe the various associated syndromes: specifically, dorsal cord, ventral cord, central cord, Brown-Séquard, conus medullaris, and cauda equina syndromes. Read More

Spinal Cord Ser Cases 2018 21;4:44. Epub 2018 May 21.

1Department of Physical Medicine, Rehabilitation and Sport Medicine, University of Puerto Rico-School of Medicine, San Juan, Puerto Rico.

Introduction: Brown-Séquard Syndrome (BSS) is one of the rarest incomplete spinal cord syndromes. The combination of injuries to peripheral nerves and the central nervous system result in an array of symptoms that can result in overlapping clinical presentations and delayed diagnosis. Early detection of spinal cord injury in patients with peripheral nerve injury has been observed to have a positive effect on outcomes. Read More

Korean J Neurotrauma 2018 Apr 30;14(1):20-23. Epub 2018 Apr 30.

Department of Neurosurgery, College of Medicine, Chosun University, Gwangju, Korea.

Objective: Acute hemiparesis is often an early presentation of acute ischemic stroke, though it can occur in various disorders. This study aimed to investigate the improper use of thrombolytic agents for patients with acute hemiparesis, following the misdiagnosis of acute ischemic stroke.

Methods: We analyzed the clinical and radiological data of nine patients initially misdiagnosed with cerebral stroke in the emergency room from May 2013 to January 2017. Read More

Trauma Surg Acute Care Open 2018 20;3(1):e000169. Epub 2018 Feb 20.

Department of Surgery, Memorial Hospital Colorado Springs, Aurora, Colorado, USA.

Case Rep Orthop 2018 4;2018:7620182. Epub 2018 Mar 4.

Laboratory of Diagnostic Pathology, Kochi Medical School, Kohasu Oko-cho, Nankoku, Kochi 783-8505, Japan.

This study reports on a 67-year-old woman with partial Brown-Séquard syndrome due to a recurrent cervical neurenteric cyst at C3 to C4. The myelopathic symptoms reappeared 22 years after a previous shunting operation performed posteriorly with a silicone tube connecting the intradural cervical cyst cavity to the subarachnoid space. We have now succeeded in removing the cyst nearly completely with the anterior approach. Read More

Neurology 2018 03;90(13):e1177-e1178

From the Division of Medicine (J.M.N.F.), Singapore Health Services; and Department of Neurology (G.J.N. and N.C.K.T.), National Neuroscience Institute, Singapore.

Asian J Neurosurg 2018 Jan-Mar;13(1):130-132

Delaware Orthopaedic Specialists, Wilmington, Delaware, USA.

Brown-Séquard syndrome, while uncommon, is a neurological condition that classically results from the hemisection of the spinal cord as a result of a penetrating injury to the spinal cord. We present a reported case of blunt trauma causing a high-energy cervical burst fracture/dislocation with a significant cord signal change producing Brown-Séquard syndrome. In this case, the burst fracture at the level of C5 obtained from the motor vehicle accident led to the damage of the left-sided lateral spinal thalamic tract, descending lateral cortical spinal tracts, and ascending dorsal column. Read More

J Clin Neurosci 2018 May 19;51:1-5. Epub 2018 Feb 19.

Department of Neurosurgery, American University of Beirut, Pierre Y. Abou Khater Building, John Kennedy Street, Beirut, Lebanon. Electronic address:

Idiopathic spinal cord herniation represents an uncommon and unique diagnostic entity, most commonly affecting middle-aged individuals, with a nearly twofold female predilection. It most characteristically affects the mid-thoracic spine, with the herniation occurring ventrally or ventrolaterally. Clinical presentation is typically a slowly-progressive myelopathy, with Brown-Séquard syndrome occurring more frequently than spastic paraparesis. Read More

World Neurosurg 2018 Apr 7;112:264-266. Epub 2018 Feb 7.

Department of Anesthesiology and Intensive Care, Military Hospital Sainte Anne, Toulon, France.

Background: While spontaneous spinal epidural hematomas are rare, 1 of the identified risk factors is vitamin K antagonist therapy.

Case Description: We present a case of a spontaneous spinal epidural hematoma occurring in a patient under treatment with dabigatran, a non-vitamin K oral anticoagulant. The initial hemiparesis symptom was misleading and was retrospectively identified as Brown-Séquard syndrome. Read More

J Stroke Cerebrovasc Dis 2018 Jun 13;27(6):e107-e109. Epub 2018 Feb 13.

Neurology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.

Infarction of the spinal cord is a rare entity in clinical practice. Limited literature exists on spinal cord stroke treatment, and the management is often symptomatic. The anterior spinal cord syndrome is the most common phenomenology, but here we present 2 nontraumatic spinal hemicord infarctions in elderly patients and discuss the clinical and radiological characteristics. Read More

J Palliat Med 2018 Mar 29;21(3):399-402. Epub 2018 Jan 29.

1 Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center , Houston, Texas.

Neuropathic pain in cancer patients is often difficult to treat, requiring a combination of several different pharmacological therapies. We describe two patients with complex neuropathic pain syndromes in the form of phantom limb pain and Brown-Sequard syndrome who did not respond to conventional treatments but responded dramatically to the addition of levorphanol. Levorphanol is a synthetic strong opioid that is a potent N-methyl-d-aspartate receptor antagonist, mu, kappa, and delta opioid receptor agonist, and reuptake inhibitor of serotonin and norepinephrine. Read More

BMJ Case Rep 2018 Jan 26;2018. Epub 2018 Jan 26.

Orthopaedic Surgery, National University Hospital, Singapore, Singapore.

Spontaneous spinal epidural haematoma (SSEH) is a rare condition that requires urgent surgical intervention in order to prevent permanent neurological deficit. SSEH commonly presents as a paraparesis or tetraparesis. SSEH presenting as a hemiparesis is less common and in such situations, it can be mistaken for a cerebrovascular accident (CVA). Read More

Eur J Intern Med 2018 08 3;54:e3-e4. Epub 2018 Jan 3.

Department of Neurology, University of Kentucky, 740 South Limestone St., Kentucky Clinic - J464, Lexington, KY 40536-0284, United States. Electronic address:

World Neurosurg 2018 Mar 16;111:94-98. Epub 2017 Dec 16.

Department of Spine Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

Background: Spinal osteochondroma is a rare but recognized cause of myelopathy. Brown-Séquard syndrome is a form of severe myelopathy characterized by a clinical picture of hemisection of the spinal cord. Brown-Séquard syndrome caused by osteochondroma is extremely rare, calling for individualized surgical procedures. Read More

J Clin Neurosci 2018 Mar 14;49:7-15. Epub 2017 Dec 14.

Department of Neurosurgery, Monash Health, Melbourne, Australia; Department of Surgery, Monash University, Melbourne, Australia. Electronic address:

Intramedullary spinal cord metastasis (ISCM) is rare and occurs most commonly in the setting of advanced malignancy. The optimal management pathways are not well defined and treatment outcomes from contemporary therapies remain variable. We report a case of a 49-year-old woman with known primary papillary thyroid carcinoma, who presented with rapidly progressive clinical features of Brown-Sequard syndrome. Read More