42,917 results match your criteria Bronchitis

Acupoint herbal patching for bronchitis: A systematic review and meta-analysis.

Medicine (Baltimore) 2022 Jul 1;101(26):e29843. Epub 2022 Jul 1.

Department of Preventive Medicine, College of Korean Medicine, Daejeon University, Daejeon, Republic of Korea.

Background: Acupoint herbal patching (AHP) has long been used to treat patients with bronchitis in East Asia. This review assessed the efficacy and safety of AHP as a treatment for bronchitis.

Methods: We performed a literature search using the 9 databases and included randomized controlled trials (RCTs) or quasi-RCTs that used AHP for bronchitis. Read More

View Article and Full-Text PDF

Increased Expression of lncRNA Regulates the Cigarette Smoke and COPD Associated Airway Inflammation and Mucous Cell Hyperplasia.

Front Immunol 2022 14;13:803362. Epub 2022 Jun 14.

Department of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, United States.

Research Impact: Cigarette smoke (CS) exposure is strongly associated with chronic obstructive pulmonary disease (COPD). In respiratory airways, CS exposure disrupts airway barrier functions, mucous/phlegm production, and basic immune responses of airway epithelial cells. Based on our recent identification of a specific immunomodulatory long noncoding RNA (lncRNA), we investigated its role in CS-induced responses in bronchial airways of cynomolgus macaque model of CS-induced COPD and in former smokers with and without COPD. Read More

View Article and Full-Text PDF

Human Bronchial Epithelial Cell Culture Models for Cigarette Smoke and Vaping Studies.

Methods Mol Biol 2022 ;2506:135-149

Department of Medicine, National Jewish Health, Denver, CO, USA.

Despite the continuing public health efforts to stop or reduce smoking, cigarette smoke use remains popular in the youth and adult population. A recent surge in the use of electronic cigarette and vaping products has created another major health challenge in public health. There is an urgent need to use physiologically relevant models to study the health effect of smoking or vaping in human subjects. Read More

View Article and Full-Text PDF
January 2022

High Expression of MUC5AC, MUC5B, and Layilin Plays an Essential Role in Prediction in the Development of Plastic Bronchitis Caused by MPP.

Front Microbiol 2022 13;13:911228. Epub 2022 Jun 13.

Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, China.

Plastic bronchitis (PB) is a rare respiratory condition which can result in severe respiratory complications such as respiratory failure and death. infection is a main etiology cause of plastic bronchitis. However, the pathogenesis of plastic bronchitis complicated by pneumonia (MPP) has not yet been fully elucidated. Read More

View Article and Full-Text PDF

Symptomatic smokers without COPD have physiological changes heralding the development of COPD.

ERJ Open Res 2022 Apr 27;8(2). Epub 2022 Jun 27.

Dept of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padua, Italy.

Background: COPD is a major health problem, mainly due to cigarette smoking. Most studies in COPD are dedicated to fully developed COPD in older subjects, even though development of COPD may start soon after smoking initiation. Therefore, there is a need to diagnose this "early disease" by detecting the initial events responsible for ultimate development of COPD. Read More

View Article and Full-Text PDF

Risk factors for habitual snoring among children aged 2-14 years in Chengdu, Sichuan.

Sleep Breath 2022 Jun 29. Epub 2022 Jun 29.

Department of Clinical Research Management, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Purpose: Habitual snoring (HS) is a prominent symptom of sleep-disordered breathing; thus, it is also important to consider the associated, multidimensional risk factors for HS in children. This study was aimed to identify risk factors for HS in children.

Methods: A cross-sectional survey was performed in Chengdu. Read More

View Article and Full-Text PDF

Public policy coverage and access to medicines in Brazil.

Rev Saude Publica 2022 24;56:58. Epub 2022 Jun 24.

Universidade Federal do Rio de Janeiro.Instituto Alberto Luiz Coimbra de Pós-Graduação e Pesquisa em Engenharia. Programa de Engenharia Biomédica. Rio de Janeiro, RJ, Brasil.

Objective: Describe consumption patterns for monetary and non-monetary acquisition of medicines according to age and income groups, highlighting pharmaceuticals associated with health programs with specific access guarantees.

Methods: Descriptive observational study using microdata from the 2017-2018 Pesquisa de Orçamentos Familiares (Household Budget Survey, POF/IBGE). We initially reviewed programs/policies with specific guarantees of access to medicines in the SUS. Read More

View Article and Full-Text PDF

Attenuated Viral Replication of Avian with a Novel 82-Nucleotide Deletion in the 5a Gene Indicates a Critical Role for 5a in Virus-Host Interactions.

Microbiol Spectr 2022 Jun 29:e0140522. Epub 2022 Jun 29.

Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing, China.

We previously found that a deletion in γ-coronavirus (IBV) accessory gene 5a is critical for decreased viral pathogenicity in chickens. Here, we systematically analyzed IBV virus infection: invasion, genome replication, subgenomic mRNA (sgmRNA) synthesis, protein synthesis, and virion release. The ability of the mutant IBV strain rYN-Δ5a to invade susceptible cells was not significantly different from that of parental rYN. Read More

View Article and Full-Text PDF

Development and validation of a nomogram to predict plastic bronchitis in children with refractory Mycoplasma pneumoniae pneumonia.

BMC Pulm Med 2022 Jun 27;22(1):253. Epub 2022 Jun 27.

Tianjin Pediatric Research Institute, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin Key Laboratory of Birth Defects for Prevention and Treatment, Tianjin, 300134, China.

Background: Early identification of plastic bronchitis (PB) is of great importance and may aid in delivering appropriate treatment. This study aimed to develop and validate a nomogram for predicting PB in patients with refractory Mycoplasma pneumoniae pneumonia (RMPP).

Methods: A total of 547 consecutive children with RMPP who underwent fiberoptic bronchoscopy (FOB) intervention from January 2016 to June 2021 were enrolled in this study. Read More

View Article and Full-Text PDF

Prevalence and comorbidities of bronchiolitis in adults: A population-based study in South Korea.

Medicine (Baltimore) 2022 Jun 24;101(25):e29551. Epub 2022 Jun 24.

Department of Internal Medicine, Research Center for Pulmonary Disorders, Jeonbuk National University Medical School, Jeonju, South Korea.

Abstract: Bronchiolitis generally refers to inflammation and/or fibrosis of the non-cartilaginous small airways located approximately from the 8th airway generation down to the terminal and respiratory bronchioles. In contrast to young children, the frequency of small airway infection in adult bronchiolitis appears less frequent and a number of other pathophysiological conditions have been implicated in adult bronchiolitis. However, little information is available on the exact medical burden of bronchiolitis such as its prevalence and comorbidities in the adult population. Read More

View Article and Full-Text PDF

Lymphatic Disorders in Patients With Single Ventricle Heart Disease.

Front Pediatr 2022 10;10:828107. Epub 2022 Jun 10.

Department of Cardiology, Jill and Mark Fishman Center for Lymphatic Disorders, Children's Hospital of Philadelphia, Philadelphia, PA, United States.

Lymphatic abnormalities in patients with single ventricle physiology can lead to early Fontan failure and severe Fontan complications, such as protein-losing enteropathy (PLE), plastic bronchitis (PB), chylothorax, and edema. Recent developments in lymphatic imaging and interventions have shed new light on the lymphatic dysfunction in this patient population and the role of the lymphatic circulation in PLE, PB, and chylothorax. In this study, we reviewed some of the latest developments in this field and discuss new treatment options for these patients. Read More

View Article and Full-Text PDF

Analysis of Microbiological and Clinical Characteristics of Bacterial Infection in Patients with Pulmonary Infection.

Taimei Duan

Comput Intell Neurosci 2022 16;2022:5607358. Epub 2022 Jun 16.

The First People's Hospital of Chongqing Liangjiang New Area, Chongqing 401121, China.

Objective: Using data investigation, the microbiology of bacterial infection in patients with pulmonary infection was discussed, and its clinical characteristics were analyzed.

Methods: The clinical data of 160 patients with pulmonary infection in our hospital from March 2019 to March 2021 were collected and analyzed. Blood samples were collected and cultured, and the pathogens were identified. Read More

View Article and Full-Text PDF

Alarmins and innate lymphoid cells 2 activation: A common pathogenetic link connecting respiratory syncytial virus bronchiolitis and later wheezing/asthma?

Pediatr Allergy Immunol 2022 06;33(6):e13803

Division of Pediatric Pulmonology, Miller School of Medicine, University of Miami, Miami, Florida, USA.

Severe respiratory syncytial virus (RSV) infection in infancy is associated with increased risk of recurrent wheezing in childhood. Both acute and long-term alterations in airway functions are thought to be related to inefficient antiviral immune response. The airway epithelium, the first target of RSV, normally acts as an immunological barrier able to elicit an effective immune reaction but may also be programmed to directly promote a Th2 response, independently from Th2 lymphocyte involvement. Read More

View Article and Full-Text PDF

Rate of Multiple Viral and Bacterial CoInfection(s) in Influenza A/H9N2-Infected Broiler Flocks.

Avian Dis 2022 Mar;66(1):1-8

Institute of Microbiology, Faculty of Veterinary Science, University of Veterinary and Animal Sciences, Lahore 54000, Pakistan,

Repeated cases of low pathogenic influenza A/H9N2 virus (IAV/H9N2) have been reported in commercial chickens since its emergence in 1998 in Pakistan. However, recently increased mortality and severe respiratory complications under field conditions have been noticed, suggesting concomitant influenza infections with respiratory viral and/or bacterial pathogens. Therefore, the present study aimed to investigate the presence of IAV/H9N2 coinfecting with multiple viral and bacterial pathogens in broiler chicken flocks. Read More

View Article and Full-Text PDF

Age-Specific Estimates of Respiratory Syncytial Virus-Associated Hospitalizations in 6 European Countries: A Time Series Analysis.

J Infect Dis 2022 Jun 24. Epub 2022 Jun 24.

Deptartment of Clinical Research, Nordsjællands University Hospital, Hilleroed, Denmark.

Background: Knowledge on age-specific hospitalizations associated with RSV infection is limited due to limited testing, especially in older children and adults in whom RSV infections are not expected to be severe. Burden estimates based on RSV coding of hospital admissions are known to underestimate the burden of RSV. We aimed to provide robust and reliable age-specific burden estimates of RSV-associated hospital admissions based on data on respiratory infections from national health registers and laboratory-confirmed cases of RSV. Read More

View Article and Full-Text PDF

Estimating the Impact of Air Pollution on Healthcare-Seeking Behaviour by Applying a Difference-in-Differences Method to Syndromic Surveillance Data.

Int J Environ Res Public Health 2022 Jun 9;19(12). Epub 2022 Jun 9.

Real-Time Syndromic Surveillance Team, Field Service, UK Health Security Agency, Birmingham B2 4BH, UK.

Syndromic surveillance data were used to estimate the direct impact of air pollution on healthcare-seeking behaviour, between 1 April 2012 and 31 December 2017. A difference-in-differences approach was used to control for spatial and temporal variations that were not due to air pollution and a meta-analysis was conducted to combine estimates from different pollution periods. Significant increases were found in general practitioner (GP) out-of-hours consultations, including a 98% increase (2-386, 95% confidence interval) in acute bronchitis and a 16% (3-30) increase in National Health Service (NHS) 111 calls for eye problems. Read More

View Article and Full-Text PDF

Genetic variation in chicken interferon signalling pathway genes in research lines showing differential viral resistance.

Anim Genet 2022 Jun 23. Epub 2022 Jun 23.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, UK.

Avian viruses of economic interest are a significant burden on the poultry industry, affecting production traits and resulting in mortality. Furthermore, the zoonosis of avian viruses risks pandemics developing in humans. Vaccination is the most common method of controlling viruses; however current vaccines often lack cross-protection against multiple strains of each virus. Read More

View Article and Full-Text PDF

Scientific Evidence about the Risks of Micro and Nanoplastics (MNPLs) to Human Health and Their Exposure Routes through the Environment.

Toxics 2022 Jun 8;10(6). Epub 2022 Jun 8.

Laboratory of Experimental and Environmental Pathology-LIM05, Department of Pathology, Faculty of Medicine, University of Sao Paulo, Sao Paulo 01246-000, Brazil.

Nowadays, a large amount and variety of plastic is being produced and consumed by human beings on an enormous scale. Microplastics and nanoplastics (MNPLs) have become ubiquitous since they can be found in many ecosystem components. Plastic particles can be found in soil, water, and air. Read More

View Article and Full-Text PDF

Ethnobotanical Uses, Phytochemical Composition, Biosynthesis, and Pharmacological Activities of L. (Asteraceae).

Plants (Basel) 2022 Jun 17;11(12). Epub 2022 Jun 17.

Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.

L. (Asteraceae) is a medicinal plant with immense therapeutic importance and bioactivities. It is commonly encountered in various Asian regions. Read More

View Article and Full-Text PDF

Complete Genome Sequences of Two JP-I (GI-18) Genotype Infectious Bronchitis Virus Strains Isolated from Chickens with Nephritis in Japan.

Microbiol Resour Announc 2022 Jun 23:e0015622. Epub 2022 Jun 23.

National Institute of Animal Health, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan.

We report the complete genome sequences of two strains of JP-1 genotype (GI-18) infectious bronchitis virus (IBV) isolated from the kidneys of dead chickens in Japan in 2000 and 2017. This information will help researchers better understand the evolution and epidemiology of IBV in Japan. Read More

View Article and Full-Text PDF

Evaluation of the multimorbidity network and its relationship with clinical phenotypes in chronic obstructive pulmonary disease: The GALAXIA study.

Clin Respir J 2022 Jun 22. Epub 2022 Jun 22.

Pneumology and Thoracic Surgery Service, University Hospital Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain.

Background: Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous condition, in which taking into consideration clinical phenotypes and multimorbidity is relevant to disease management. Network analysis, a procedure designed to study complex systems, allows to represent connections between the distinct features found in COPD.

Methods: Network analysis was applied to a cohort of patients with COPD in order to explore the degree of connectivity between different diseases, taking into account the presence of two phenotypic traits commonly used to categorize patients in clinical practice: chronic bronchitis (CB /CB ) and the history of previous severe exacerbations (Ex /Ex ). Read More

View Article and Full-Text PDF

[Influence of age of patients with bronchopulmonary pathology on low-molecular DNA concentration in blood plasma.]

Adv Gerontol 2022 ;35(2):281-286

N.N.Petrov National Medical Research Center of Oncology, 68 Leningradskaya str., Pesochnyi, St. Petersburg 197758, Russian Federation, e-mail:

The aim of the work was to determine the concentration of low-molecular-weight plasma DNA (lmDNA) in patients with COPD and chronic non-obstructive bronchitis (CnonB) of two age groups - 34-59 and 60-80 years. The levels of lmDNA in healthy donors, patients with CnonB, healthy relatives of patients with COPD did not differ, while the concentration of lmDNA in patients with COPD was significantly lower. In COPD patients aged 34-59 years, the level of lmDNA was reduced by more than 7 times, and in COPD patients who survived to 60-80 years, it was 3 times lower compared to the value of this biochemical indicator in healthy donors of the same age. Read More

View Article and Full-Text PDF

Modulation of Viral Replication, Apoptosis and Antiviral Response by Induction and Mutual Regulation of EGR and AP-1 Family Genes During Coronavirus Infection.

Emerg Microbes Infect 2022 Jun 21:1-34. Epub 2022 Jun 21.

Integrative Microbiology Research Centre, South China Agricultural University, Guangzhou 510642, Guangdong, People's Republic of China.

Coronaviruses have evolved a variety of strategies to exploit normal cellular processes and signalling pathways for their efficient reproduction in a generally hostile cellular environment. One immediate-early response gene (IEG) family, the AP-1 gene family, was previously shown to be activated by coronavirus infection. In this study, we report that another IEG family, the EGR family, is also activated in cells infected with four different coronaviruses in three genera, i. Read More

View Article and Full-Text PDF

Abandon Noninvasive Ventilation in Bronchiolitis? How Unrecognized Bias Can Lead to Problematic Conclusions.

Crit Care Med 2022 Jul 13;50(7):e653-e654e. Epub 2022 Jun 13.

Department of Anesthesia and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.

View Article and Full-Text PDF

High Frequency Percussive Ventilation in Viral Bronchiolitis: Do We Need a Standardized Approach to HFPV Management?

Respir Care 2022 07;67(7):893-894

Department of Anesthesia and Critical Care The Children's Hospital of Philadelphia University of Pennsylvania Perelman School of Medicinea Philadelphia, Pennsylvania.

View Article and Full-Text PDF

Childhood 'bronchitis' and respiratory outcomes in middle-age: a prospective cohort study from age 7 to 53 years.

BMJ Open Respir Res 2022 06;9(1)

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.

Background: Chronic bronchitis in childhood is associated with a diagnosis of asthma and/or bronchiectasis a few years later, however, consequences into middle-age are unknown.

Objective: To investigate the relationship between childhood bronchitis and respiratory-related health outcomes in middle-age.

Design: Cohort study from age 7 to 53 years. Read More

View Article and Full-Text PDF

The First Occurrence of Hepatitis-Hydropericardium Syndrome in Iran and Effective Applied Control Measures in the Affected Commercial Broiler Flock.

Avian Dis 2022 Jun 15. Epub 2022 Jun 15.

Veterinary Head Office of Khorasan Razavi province, 9185333446, Mashhad, Iran.

Fowl adenoviruses cause three economically important diseases in broiler chicken flocks: hepatitis-hydropericardium syndrome (HHS), inclusion body hepatitis (IBH), and adenoviral gizzard erosion. IBH has not been considered a serious threat in northeast Iran since the last decade, because no major effect on flock performance has been noticed along with a low mortality rate. During this period, all the sporadic IBH outbreaks have also been investigated for HHS without finding any confirmed case. Read More

View Article and Full-Text PDF

Contribution of smoking change to 45-year trend in prevalence of chronic bronchitis in Finland.

Scand J Public Health 2022 Jun 19:14034948221104351. Epub 2022 Jun 19.

Department of Public Health and Welfare, Finnish institute for Health and Welfare, Helsinki, Finland.

Aims: Tobacco smoking has been identified as the most important risk factor of chronic bronchitis. The aim of this study was to assess the contribution of smoking to the trends in prevalence of chronic bronchitis among men and women in Finland.

Methods: For this purpose, we analysed questionnaires included in national FINRISK and FinHealth studies conducted between 1972 and 2017 in 5-year intervals. Read More

View Article and Full-Text PDF

The traditional uses, phytochemistry and pharmacology of Abrus precatorius L.: A comprehensive review.

J Ethnopharmacol 2022 Jun 14;296:115463. Epub 2022 Jun 14.

College of Pharmacy, Sanquan College of Xinxiang Medical University, Xinxiang, 453000, China.

Ethnopharmacological Relevance: Abrus precatorius L. (AP) is a folk medicine with a long-term medicinal history worldwide, which is extensively applied to various ailments, such as bronchitis, jaundice, hepatitis, contraception, tumor, abortion, malaria, etc. Meanwhile, its leaves are also served as tea in China, and its roots are employed as a substitute for Glycyrrhiza uralensis or as a raw material for the extraction of glycyrrhizin in India. Read More

View Article and Full-Text PDF